| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 28 | Matt Olson | 27 | 1B | L | 121 | 156 | 565 | 101 | 153 | 35 | 0 | 39 | 111 | 4 | 1 | 88 | 113 | 9 | 0 | 11 | 12 | 17 | 305 | 673 | 74 | 79 | .271 | .371 | .540 | .911 | .430 | .269 | .269 | 13.08 | 16.79 | 1.28 | 14.49 | 2012- 1- 47-OAK | premium | premium | premium | MLB | 2016-2026 | 2012-2026 | 2021 |
| 26 | Matt Chapman | 28 | 3B | R | 99 | 151 | 529 | 75 | 111 | 15 | 3 | 27 | 72 | 3 | 2 | 80 | 202 | 4 | 0 | 9 | 0 | 6 | 213 | 622 | 45 | 66 | .210 | .314 | .403 | .717 | .346 | .193 | .272 | 12.86 | 32.48 | 2.53 | 19.59 | 2014- 1- 25-OAK | premium | premium | premium | MLB | 2017-2026 | 2012-2026 | 2021 |
| 20 | Mark Canha | 32 | LF | R | 106 | 141 | 519 | 93 | 120 | 22 | 4 | 17 | 61 | 12 | 2 | 77 | 128 | 27 | 0 | 2 | 0 | 9 | 201 | 625 | 43 | 77 | .231 | .358 | .387 | .745 | .324 | .156 | .274 | 12.32 | 20.48 | 1.66 | 30.53 | 2010- 7- 227-MIA | premium | premium | premium | MLB | 2015-2025 | 2008-2025 | 2021 |
| 17 | Elvis Andrus | 32 | SS | R | 86 | 146 | 497 | 60 | 121 | 25 | 2 | 3 | 37 | 12 | 2 | 31 | 81 | 6 | 3 | 4 | 2 | 14 | 159 | 541 | 30 | 91 | .243 | .294 | .320 | .614 | .159 | .077 | .283 | 5.73 | 14.97 | 2.61 | 165.67 | 2005- UDFA -ATL | premium | premium | premium | MLB | 2009-2023 | 2005-2023 | 2021 |
| 8 | Jed Lowrie | 37 | 2B-DH | B | 99 | 139 | 457 | 55 | 112 | 28 | 0 | 14 | 69 | 0 | 0 | 49 | 108 | 2 | 0 | 4 | 1 | 8 | 182 | 512 | 42 | 70 | .245 | .318 | .398 | .716 | .260 | .153 | .289 | 9.57 | 21.09 | 2.20 | 32.64 | 2005- 1- 45-BOS | premium | premium | premium | MLB | 2008-2022 | 2003-2022 | 2021 |
| 12 | Sean Murphy | 26 | C | R | 98 | 119 | 393 | 47 | 85 | 23 | 0 | 17 | 59 | 0 | 0 | 40 | 114 | 12 | 0 | 3 | 0 | 7 | 159 | 448 | 40 | 45 | .216 | .306 | .405 | .711 | .290 | .189 | .257 | 8.93 | 25.45 | 2.85 | 23.12 | 2016- 3- 83-OAK | premium | premium | premium | MLB | 2019-2026 | 2014-2026 | 2021 |
| 22 | Ramon Laureano | 26 | CF | R | 104 | 88 | 341 | 43 | 84 | 21 | 2 | 14 | 39 | 12 | 5 | 27 | 98 | 9 | 0 | 1 | 0 | 4 | 151 | 378 | 37 | 47 | .246 | .317 | .443 | .760 | .296 | .197 | .304 | 7.14 | 25.93 | 3.63 | 24.36 | 2014- 16- 466-HOU | premium | premium | premium | MLB | 2018-2026 | 2013-2026 | 2021 |
| 5 | Tony Kemp | 29 | 2B-LF | L | 112 | 131 | 330 | 54 | 92 | 16 | 3 | 8 | 37 | 8 | 2 | 52 | 51 | 6 | 4 | 5 | 0 | 2 | 138 | 397 | 27 | 65 | .279 | .382 | .418 | .800 | .315 | .139 | .304 | 13.10 | 12.85 | 0.98 | 41.25 | 2013- 5- 137-HOU | premium | premium | premium | MLB | 2016-2024 | 2011-2024 | 2021 |
| 15 | Seth Brown | 28 | RF | L | 101 | 111 | 281 | 43 | 60 | 13 | 1 | 20 | 48 | 4 | 1 | 23 | 89 | 1 | 0 | 2 | 2 | 1 | 135 | 307 | 34 | 26 | .214 | .274 | .480 | .754 | .359 | .266 | .230 | 7.49 | 28.99 | 3.87 | 14.05 | 2015- 19- 578-OAK | premium | premium | premium | MLB | 2019-2025 | 2013-2026 | 2021 |
| 6 | Starling Marte | 32 | CF | R | 119 | 56 | 234 | 37 | 73 | 16 | 2 | 5 | 30 | 25 | 2 | 11 | 42 | 5 | 0 | 1 | 0 | 4 | 108 | 251 | 23 | 50 | .312 | .355 | .462 | .817 | .295 | .150 | .362 | 4.38 | 16.73 | 3.82 | 46.80 | 2007- UDFA -PIT | premium | premium | premium | MLB | 2012-2026 | 2009-2026 | 2021 |
| 18 | Mitch Moreland | 35 | DH | L | 95 | 81 | 229 | 28 | 52 | 11 | 1 | 10 | 30 | 0 | 0 | 18 | 58 | 2 | 0 | 3 | 0 | 5 | 95 | 252 | 22 | 30 | .227 | .286 | .415 | .701 | .266 | .188 | .256 | 7.14 | 23.02 | 3.22 | 22.90 | 2007- 17- 530-TEX | premium | premium | premium | MLB | 2010-2021 | 2005-2021 | 2021 |
| 4 | Chad Pinder | 29 | RF | R | 98 | 75 | 214 | 30 | 52 | 16 | 1 | 6 | 27 | 1 | 0 | 16 | 62 | 2 | 0 | 1 | 0 | 6 | 88 | 233 | 23 | 29 | .243 | .300 | .411 | .711 | .248 | .168 | .313 | 6.87 | 26.61 | 3.88 | 35.67 | 2013- 2- 71-OAK | premium | premium | premium | MLB | 2016-2022 | 2011-2023 | 2021 |
| 5 | Josh Harrison | 33 | 2B | R | 102 | 48 | 185 | 19 | 47 | 10 | 0 | 2 | 22 | 4 | 3 | 6 | 25 | 6 | 0 | 2 | 0 | 5 | 63 | 199 | 12 | 35 | .254 | .296 | .341 | .637 | .124 | .087 | .281 | 3.02 | 12.56 | 4.17 | 92.50 | 2008- 6- 191-CHN | premium | premium | premium | MLB | 2011-2023 | 2006-2023 | 2021 |
| 25 | Stephen Piscotty | 30 | RF | R | 89* | 72 | 173 | 14 | 38 | 8 | 0 | 5 | 16 | 1 | 0 | 13 | 48 | 2 | 0 | 0 | 0 | 2 | 61 | 188 | 13 | 25 | .220 | .282 | .353 | .635 | .214 | .133 | .275 | 6.91 | 25.53 | 3.69 | 34.60 | 2012- 1- 36-SLN | premium | premium | premium | MLB | 2015-2022 | 2010-2024 | 2021 |
| 10 | Yan Gomes | 33 | C | R | 98 | 40 | 131 | 19 | 29 | 4 | 0 | 5 | 17 | 0 | 0 | 6 | 31 | 2 | 0 | 1 | 0 | 3 | 48 | 140 | 9 | 20 | .221 | .264 | .366 | .630 | .191 | .145 | .250 | 4.29 | 22.14 | 5.17 | 26.20 | 2009- 10- 310-TOR | premium | premium | premium | MLB | 2012-2024 | 2007-2024 | 2021 |
| 37 | Aramis Garcia | 28 | C | R | 32 | 88 | 8 | 18 | 1 | 0 | 3 | 7 | 0 | 0 | 1 | 28 | 3 | 2 | 0 | 0 | 4 | 28 | 94 | 4 | 14 | .205 | .239 | .318 | .557 | .125 | .113 | .263 | 1.06 | 29.79 | 28.00 | 29.33 | 2014- 2- 52-SFN | premium | premium | premium | MLB | 2018-2026 | 2012-2026 | 2021 | |
| 65 | Skye Bolt | 27 | CF | B | 32 | 56 | 5 | 5 | 1 | 0 | 1 | 4 | 2 | 0 | 1 | 14 | 0 | 2 | 0 | 0 | 0 | 9 | 59 | 2 | 3 | .089 | .105 | .161 | .266 | .125 | .072 | .098 | 1.69 | 23.73 | 14.00 | 56.00 | 2015- 4- 128-OAK | premium | premium | premium | MLB | 2019-2022 | 2013-2024 | 2021 | |
| 4 | Khris Davis | 33 | DH | R | 87* | 20 | 51 | 3 | 13 | 4 | 0 | 1 | 5 | 0 | 0 | 2 | 15 | 0 | 0 | 0 | 0 | 0 | 20 | 53 | 5 | 8 | .255 | .283 | .392 | .675 | .176 | .137 | .343 | 3.77 | 28.30 | 7.50 | 51.00 | 2009- 7- 226-MIL | premium | premium | premium | MLB | 2013-2021 | 2007-2022 | 2021 |
| 31 | Vimael Machin | 27 | SS | L | 15 | 32 | 1 | 4 | 0 | 0 | 0 | 1 | 0 | 0 | 3 | 10 | 0 | 2 | 0 | 0 | 2 | 4 | 37 | 0 | 4 | .125 | .200 | .125 | .325 | .094 | .000 | .182 | 8.11 | 27.03 | 3.33 | 0.00 | 2015- 10- 293-CHN | premium | premium | premium | MLB | 2020-2025 | 2012-2026 | 2021 | |
| 18 | Frank Schwindel | 29 | DH | R | 128 | 8 | 20 | 2 | 3 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 7 | 20 | 2 | 1 | .150 | .150 | .350 | .500 | .200 | .200 | .143 | 0.00 | 25.00 | 0.00 | 20.00 | 2013- 18- 534-KCA | premium | premium | premium | MLB | 2019-2022 | 2011-2025 | 2021 |
| 60 | Ka'ai Tom | 27 | RF-DH | L | 76* | 9 | 16 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 1 | 16 | 0 | 1 | .063 | .063 | .063 | .126 | .000 | .000 | .100 | 0.00 | 37.50 | 0.00 | 0.00 | 2015- 5- 154-CLE | premium | premium | premium | MLB | 2021-2022 | 2013-2022 | 2021 |
| 38 | Pete Kozma | 33 | SS | R | 3 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 12 | 0 | 1 | .091 | .167 | .091 | .258 | .091 | .000 | .143 | 8.33 | 33.33 | 4.00 | 0.00 | 2007- 1- 18-SLN | premium | premium | premium | MLB | 2011-2021 | 2007-2023 | 2021 | |
| 13 | Luis Barrera | 25 | RF-LF | L | 6 | 8 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 8 | 0 | 2 | .250 | .250 | .250 | .500 | .000 | .000 | .333 | 0.00 | 25.00 | 0.00 | 0.00 | 2012- UDFA -OAK | premium | premium | premium | MLB | 2021-2022 | 2013-2025 | 2021 | |
| 30 | Austin Allen | 27 | C-DH | L | 4 | 8 | 2 | 2 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 5 | 8 | 1 | 1 | .250 | .250 | .625 | .875 | .375 | .375 | .250 | 0.00 | 37.50 | 0.00 | 8.00 | 2015- 4- 117-SDN | premium | premium | premium | MLB | 2019-2022 | 2013-2025 | 2021 | |
| 13 | Jacob Wilson | 30 | 2B | R | 6 | 7 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 7 | 0 | 1 | .143 | .143 | .143 | .286 | .000 | .000 | .167 | 0.00 | 14.29 | 0.00 | 0.00 | 2012- 10- 330-SLN | premium | premium | premium | MLB | 2021-2021 | 2009-2021 | 2021 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 19 | Cole Irvin | 27 | P | L | 2 | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 2 | 0 | 0 | 0 | 1 | 7 | 0 | 1 | .200 | .200 | .200 | .400 | .000 | .000 | .333 | 0.00 | 28.57 | 0.00 | 0.00 | 2016- 5- 137-PHI | premium | premium | premium | MLB | 2019-2026 | 2013-2026 | 2021 | |
| 55 | Sean Manaea | 29 | P | R | 2 | 4 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 3 | 5 | 1 | 1 | .500 | .500 | .750 | 1.250 | .250 | .250 | .667 | 0.00 | 20.00 | 0.00 | 0.00 | 2013- 1- 34-KCA | premium | premium | premium | MLB | 2016-2026 | 2011-2026 | 2021 | |
| 47 | Frankie Montas | 28 | P | R | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 75.00 | 0.00 | 0.00 | 2009- UDFA -BOS | premium | premium | premium | MLB | 2015-2025 | 2010-2025 | 2021 | |
| 32 | James Kaprielian | 27 | P | R | 2 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .333 | .333 | .333 | .666 | .000 | .000 | 1.000 | 0.00 | 50.00 | 0.00 | 0.00 | 2015- 1- 16-NYA | premium | premium | premium | MLB | 2020-2023 | 2013-2024 | 2021 | |
| 40 | Chris Bassitt | 32 | P | R | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2011- 16- 501-CHA | premium | premium | premium | MLB | 2014-2026 | 2008-2026 | 2021 | |
| 35 | Jake Diekman | 34 | P | R | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2007- 30- 923-PHI | premium | premium | premium | MLB | 2012-2024 | 2007-2025 | 2021 | |
| 44 | Jesus Luzardo | 23 | P | L | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2016- 3- 94-WAS | premium | premium | premium | MLB | 2019-2026 | 2017-2026 | 2021 | |
| Totals: | 1704 | 5395 | 743 | 1283 | 271 | 19 | 199 | 698 | 88 | 20 | 545 | 1349 | 98 | 17 | 49 | 17 | 99 | 2189 | 6104 | 489 | 794 | .238 | .316 | .406 | .722 | .282 | .168 | .278 | 8.93 | 22.10 | 2.48 | 27.11 | premium | premium | premium |
| # | player | age | th | tbc+ | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 47 | Frankie Montas | 28 | R | 111 | 13 | 9 | 3.37 | 32 | 32 | 0 | 0 | 0 | 0 | 0 | 187.0 | 164 | 79 | 70 | 20 | 57 | 207 | 11 | 0 | 7 | 1.18 | 7.89 | 0.96 | 2.74 | 9.96 | 3.80 | 3.63 | 2009- UDFA -BOS | premium | premium | premium | MLB | 2015-2025 | 2010-2025 | 2021 |
| 55 | Sean Manaea | 29 | L | 106 | 11 | 10 | 3.91 | 32 | 32 | 2 | 2 | 0 | 0 | 0 | 179.1 | 179 | 79 | 78 | 25 | 41 | 194 | 5 | 1 | 9 | 1.23 | 8.98 | 1.25 | 2.06 | 9.74 | 3.96 | 4.73 | 2013- 1- 34-KCA | premium | premium | premium | MLB | 2016-2026 | 2011-2026 | 2021 |
| 19 | Cole Irvin | 27 | L | 90 | 10 | 15 | 4.24 | 32 | 32 | 0 | 0 | 0 | 0 | 0 | 178.1 | 195 | 94 | 84 | 23 | 42 | 125 | 3 | 0 | 9 | 1.33 | 9.84 | 1.16 | 2.12 | 6.31 | 4.74 | 2.98 | 2016- 5- 137-PHI | premium | premium | premium | MLB | 2019-2026 | 2013-2026 | 2021 |
| 40 | Chris Bassitt | 32 | R | 115 | 12 | 4 | 3.15 | 27 | 27 | 1 | 1 | 0 | 0 | 0 | 157.1 | 127 | 55 | 55 | 15 | 39 | 159 | 5 | 1 | 11 | 1.06 | 7.26 | 0.86 | 2.23 | 9.10 | 3.15 | 4.08 | 2011- 16- 501-CHA | premium | premium | premium | MLB | 2014-2026 | 2008-2026 | 2021 |
| 32 | James Kaprielian | 27 | R | 104 | 8 | 5 | 4.07 | 24 | 21 | 0 | 0 | 3 | 0 | 0 | 119.1 | 105 | 55 | 54 | 19 | 41 | 123 | 1 | 0 | 5 | 1.22 | 7.92 | 1.43 | 3.09 | 9.28 | 4.15 | 3.00 | 2015- 1- 16-NYA | premium | premium | premium | MLB | 2020-2023 | 2013-2024 | 2021 |
| 36 | Yusmeiro Petit | 36 | R | 101 | 8 | 3 | 3.92 | 78 | 0 | 0 | 0 | 78 | 10 | 2 | 78.0 | 69 | 35 | 34 | 12 | 12 | 37 | 1 | 0 | 1 | 1.04 | 7.96 | 1.38 | 1.38 | 4.27 | 4.04 | 3.08 | 2001- UDFA -NYN | premium | premium | premium | MLB | 2006-2021 | 2003-2022 | 2021 |
| 62 | Lou Trivino | 29 | R | 104 | 7 | 8 | 3.18 | 71 | 0 | 0 | 0 | 71 | 44 | 22 | 73.2 | 58 | 32 | 26 | 5 | 34 | 67 | 7 | 0 | 4 | 1.25 | 7.09 | 0.61 | 4.15 | 8.19 | 3.91 | 1.97 | 2013- 11- 341-OAK | premium | premium | premium | MLB | 2018-2026 | 2011-2026 | 2021 |
| 65 | Deolis Guerra | 32 | R | 108 | 4 | 1 | 4.11 | 53 | 0 | 0 | 0 | 53 | 14 | 0 | 65.2 | 53 | 34 | 30 | 8 | 20 | 62 | 1 | 0 | 4 | 1.11 | 7.26 | 1.10 | 2.74 | 8.50 | 4.66 | 3.10 | 2005- UDFA -NYN | premium | premium | premium | MLB | 2015-2021 | 2006-2025 | 2021 |
| 54 | Sergio Romo | 38 | R | 102 | 1 | 1 | 4.67 | 66 | 0 | 0 | 0 | 66 | 18 | 3 | 61.2 | 56 | 33 | 32 | 9 | 21 | 60 | 1 | 0 | 2 | 1.25 | 8.17 | 1.31 | 3.06 | 8.76 | 4.82 | 2.86 | 2005- 28- 852-SFN | premium | premium | premium | MLB | 2008-2022 | 2005-2022 | 2021 |
| 35 | Jake Diekman | 34 | L | 108 | 3 | 3 | 3.86 | 67 | 0 | 0 | 0 | 67 | 17 | 7 | 60.2 | 47 | 29 | 26 | 10 | 34 | 83 | 8 | 0 | 4 | 1.34 | 6.97 | 1.48 | 5.04 | 12.31 | 4.30 | 2.44 | 2007- 30- 923-PHI | premium | premium | premium | MLB | 2012-2024 | 2007-2025 | 2021 |
| 46 | Burch Smith | 31 | R | 88 | 1 | 1 | 5.40 | 31 | 0 | 0 | 0 | 31 | 10 | 0 | 43.1 | 49 | 27 | 26 | 5 | 11 | 28 | 2 | 0 | 1 | 1.38 | 10.18 | 1.04 | 2.28 | 5.82 | 5.61 | 2.55 | 2011- 14- 443-SDN | premium | premium | premium | MLB | 2013-2026 | 2011-2026 | 2021 |
| 58 | Paul Blackburn | 27 | R | 77* | 1 | 4 | 5.87 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 38.1 | 52 | 26 | 25 | 8 | 10 | 26 | 1 | 0 | 2 | 1.62 | 12.21 | 1.88 | 2.35 | 6.10 | 6.10 | 2.60 | 2012- 1- 56-CHN | premium | premium | premium | MLB | 2017-2026 | 2012-2026 | 2021 |
| 44 | Jesus Luzardo | 23 | L | 88 | 2 | 4 | 6.87 | 13 | 6 | 0 | 0 | 7 | 1 | 0 | 38.0 | 46 | 32 | 29 | 11 | 16 | 40 | 3 | 0 | 0 | 1.63 | 10.89 | 2.61 | 3.79 | 9.47 | 7.58 | 2.50 | 2016- 3- 94-WAS | premium | premium | premium | MLB | 2019-2026 | 2017-2026 | 2021 |
| 39 | Andrew Chafin | 31 | L | 127 | 2 | 2 | 1.53 | 28 | 0 | 0 | 0 | 28 | 10 | 5 | 29.1 | 24 | 5 | 5 | 3 | 7 | 27 | 1 | 0 | 0 | 1.06 | 7.36 | 0.92 | 2.15 | 8.28 | 1.53 | 3.86 | 2011- 1- 43-ARI | premium | premium | premium | MLB | 2014-2025 | 2009-2026 | 2021 |
| 48 | J.B. Wendelken | 28 | R | 93 | 2 | 1 | 4.32 | 26 | 0 | 0 | 0 | 26 | 6 | 0 | 25.0 | 29 | 15 | 12 | 2 | 13 | 26 | 4 | 0 | 0 | 1.68 | 10.44 | 0.72 | 4.68 | 9.36 | 5.40 | 2.00 | 2012- 13- 421-BOS | premium | premium | premium | MLB | 2016-2022 | 2012-2025 | 2021 |
| 66 | Daulton Jefferies | 25 | R | 1 | 0 | 3.60 | 5 | 1 | 0 | 0 | 4 | 1 | 0 | 15.0 | 11 | 6 | 6 | 1 | 4 | 8 | 1 | 0 | 1 | 1.00 | 6.60 | 0.60 | 2.40 | 4.80 | 3.60 | 2.00 | 2016- 1- 37-OAK | premium | premium | premium | MLB | 2020-2024 | 2014-2024 | 2021 | |
| 61 | Reymin Guduan | 29 | L | 0 | 0 | 6.28 | 11 | 0 | 0 | 0 | 11 | 6 | 0 | 14.1 | 19 | 11 | 10 | 1 | 5 | 5 | 5 | 0 | 0 | 1.67 | 11.93 | 0.63 | 3.14 | 3.14 | 6.91 | 1.00 | 2009- UDFA -HOU | premium | premium | premium | MLB | 2017-2021 | 2010-2025 | 2021 | |
| 33 | A.J. Puk | 26 | L | 0 | 3 | 6.08 | 12 | 0 | 0 | 0 | 12 | 3 | 0 | 13.1 | 18 | 9 | 9 | 1 | 6 | 16 | 2 | 0 | 1 | 1.80 | 12.15 | 0.68 | 4.05 | 10.80 | 6.08 | 2.67 | 2016- 1- 6-OAK | premium | premium | premium | MLB | 2019-2025 | 2014-2026 | 2021 | |
| 68 | Domingo Acevedo | 27 | R | 0 | 0 | 3.27 | 10 | 0 | 0 | 0 | 10 | 7 | 0 | 11.0 | 9 | 4 | 4 | 3 | 4 | 9 | 0 | 0 | 0 | 1.18 | 7.36 | 2.45 | 3.27 | 7.36 | 3.27 | 2.25 | 2012- UDFA -NYA | premium | premium | premium | MLB | 2021-2023 | 2013-2026 | 2021 | |
| 60 | Sam Moll | 29 | L | 0 | 0 | 3.48 | 8 | 0 | 0 | 0 | 8 | 1 | 0 | 10.1 | 8 | 4 | 4 | 1 | 5 | 8 | 0 | 0 | 2 | 1.26 | 6.97 | 0.87 | 4.35 | 6.97 | 3.48 | 1.60 | 2013- 3- 77-COL | premium | premium | premium | MLB | 2017-2026 | 2011-2026 | 2021 | |
| 50 | Mike Fiers | 36 | R | 0 | 2 | 7.71 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 9.1 | 15 | 8 | 8 | 4 | 4 | 5 | 0 | 0 | 0 | 2.04 | 14.46 | 3.86 | 3.86 | 4.82 | 7.71 | 1.25 | 2009- 22- 676-MIL | premium | premium | premium | MLB | 2011-2021 | 2009-2022 | 2021 | |
| 21 | Adam Kolarek | 32 | L | 0 | 0 | 8.00 | 12 | 0 | 0 | 0 | 12 | 2 | 0 | 9.0 | 15 | 10 | 8 | 2 | 5 | 4 | 1 | 0 | 1 | 2.22 | 15.00 | 2.00 | 5.00 | 4.00 | 10.00 | 0.80 | 2010- 11- 332-NYN | premium | premium | premium | MLB | 2017-2023 | 2008-2024 | 2021 | |
| 46 | Cam Bedrosian | 29 | R | 81* | 0 | 0 | 2.00 | 9 | 0 | 0 | 0 | 9 | 4 | 0 | 9.0 | 9 | 2 | 2 | 2 | 4 | 8 | 0 | 0 | 0 | 1.44 | 9.00 | 2.00 | 4.00 | 8.00 | 2.00 | 2.00 | 2010- 1- 29-ANA | premium | premium | premium | MLB | 2014-2021 | 2010-2024 | 2021 |
| 41 | Jordan Weems | 28 | R | 0 | 0 | 6.23 | 5 | 0 | 0 | 0 | 5 | 3 | 0 | 4.1 | 2 | 3 | 3 | 1 | 3 | 4 | 0 | 0 | 0 | 1.15 | 4.15 | 2.08 | 6.23 | 8.31 | 6.23 | 1.33 | 2011- 3- 111-BOS | premium | premium | premium | MLB | 2020-2025 | 2011-2026 | 2021 | |
| 18 | Mitch Moreland | 35 | L | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.00 | 9.00 | 0.00 | 0.00 | 9.00 | 0.00 | 0.00 | 2007- 17- 530-TEX | premium | premium | premium | MLB | 2010-2021 | 2005-2021 | 2021 | |
| # | player | age | th | tbc+ | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 60 | Ka'ai Tom | 27 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 | 9.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2015- 5- 154-CLE | premium | premium | premium | MLB | 2021-2022 | 2013-2022 | 2021 | |
| 48 | Michael Feliz | 28 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0.1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.00 | 27.00 | 0.00 | 27.00 | 0.00 | 0.00 | 0.00 | 2010- UDFA -HOU | premium | premium | premium | MLB | 2015-2022 | 2010-2025 | 2021 | |
| Totals: | 86 | 76 | 4.02 | 666 | 162 | 3 | 3 | 504 | 159 | 39 | 1433.0 | 1362 | 687 | 640 | 191 | 439 | 1332 | 63 | 2 | 64 | 1.26 | 8.55 | 1.20 | 2.76 | 8.37 | 4.31 | 3.03 | premium | premium | premium |