| 2022-04-05 | April | Iowa Cubs | Home | W | 3-2 | boxscore | 10,145 | 2:26 | 1-0 | Sahlen Field | Buffalo,New York |
| 2022-04-06 | April | Iowa Cubs | Home | L | 4-8 | boxscore | 3,921 | 3:34 | 1-1 | Sahlen Field | Buffalo,New York |
| 2022-04-08 | April | Iowa Cubs | Home | W | 7-2 | boxscore | 0 | 2:20 | 2-1 | Sahlen Field | Buffalo,New York |
| 2022-04-08 | April | Iowa Cubs | Home | W | 1-0 | boxscore | 4,027 | 1:53 | 3-1 | Sahlen Field | Buffalo,New York |
| 2022-04-09 | April | Iowa Cubs | Home | L | 3-4 | boxscore | 3,944 | 2:46 | 3-2 | Sahlen Field | Buffalo,New York |
| 2022-04-10 | April | Iowa Cubs | Home | W | 2-1 | boxscore | 3,912 | 2:38 | 4-2 | Sahlen Field | Buffalo,New York |
| 2022-04-12 | April | Rochester Red Wings | Vis | W | 6-4 | boxscore | 8,170 | 3:17 | 5-2 | Frontier Field | Rochester,New York |
| 2022-04-14 | April | Rochester Red Wings | Vis | W | 10-1 | boxscore | 2,902 | 3:10 | 6-2 | Frontier Field | Rochester,New York |
| 2022-04-15 | April | Rochester Red Wings | Vis | L | 2-3 | boxscore | 0 | 1:53 | 6-3 | Frontier Field | Rochester,New York |
| 2022-04-15 | April | Rochester Red Wings | Vis | W | 9-4 | boxscore | 3,709 | 2:27 | 7-3 | Frontier Field | Rochester,New York |
| 2022-04-16 | April | Rochester Red Wings | Vis | L | 10-11 | boxscore | 2,920 | 3:34 | 7-4 | Frontier Field | Rochester,New York |
| 2022-04-17 | April | Rochester Red Wings | Vis | L | 1-8 | boxscore | 2,462 | 2:17 | 7-5 | Frontier Field | Rochester,New York |
| 2022-04-20 | April | Scranton/Wilkes-Barre RailRiders | Home | W | 2-1 | boxscore | 0 | 1:42 | 8-5 | Sahlen Field | Buffalo,New York |
| 2022-04-20 | April | Scranton/Wilkes-Barre RailRiders | Home | W | 6-5 | boxscore | 4,009 | 2:22 | 9-5 | Sahlen Field | Buffalo,New York |
| 2022-04-21 | April | Scranton/Wilkes-Barre RailRiders | Home | W | 7-3 | boxscore | 3,932 | 2:41 | 10-5 | Sahlen Field | Buffalo,New York |
| 2022-04-22 | April | Scranton/Wilkes-Barre RailRiders | Home | L | 3-5 | boxscore | 4,558 | 2:36 | 10-6 | Sahlen Field | Buffalo,New York |
| 2022-04-23 | April | Scranton/Wilkes-Barre RailRiders | Home | L | 4-7 | boxscore | 4,717 | 2:55 | 10-7 | Sahlen Field | Buffalo,New York |
| 2022-04-24 | April | Scranton/Wilkes-Barre RailRiders | Home | W | 4-0 | boxscore | 8,154 | 2:11 | 11-7 | Sahlen Field | Buffalo,New York |
| 2022-04-27 | April | Worcester Red Sox | Vis | L | 2-4 | boxscore | 0 | 1:36 | 11-8 | Polar Park | Worcester,Massachusetts |
| 2022-04-27 | April | Worcester Red Sox | Vis | W | 7-5 | boxscore | 5,892 | 2:21 | 12-8 | Polar Park | Worcester,Massachusetts |
| 2022-04-28 | April | Worcester Red Sox | Vis | W | 5-4 | boxscore | 5,884 | 2:51 | 13-8 | Polar Park | Worcester,Massachusetts |
| 2022-04-29 | April | Worcester Red Sox | Vis | L | 6-8 | boxscore | 8,472 | 2:50 | 13-9 | Polar Park | Worcester,Massachusetts |
| 2022-04-30 | April | Worcester Red Sox | Vis | W | 9-7 | boxscore | 8,867 | 3:02 | 14-9 | Polar Park | Worcester,Massachusetts |
| 2022-05-01 | May | Worcester Red Sox | Vis | L | 6-10 | boxscore | 9,103 | 2:51 | 14-10 | Polar Park | Worcester,Massachusetts |
| 2022-05-04 | May | Durham Bulls | Home | L | 1-5 | boxscore | 0 | 2:05 | 14-11 | Sahlen Field | Buffalo,New York |
| 2022-05-04 | May | Durham Bulls | Home | W | 5-0 | boxscore | 3,998 | 1:36 | 15-11 | Sahlen Field | Buffalo,New York |
| 2022-05-05 | May | Durham Bulls | Home | L | 4-5 | boxscore | 4,065 | 2:40 | 15-12 | Sahlen Field | Buffalo,New York |
| 2022-05-06 | May | Durham Bulls | Home | W | 5-4 | boxscore | 4,857 | 2:44 | 16-12 | Sahlen Field | Buffalo,New York |
| 2022-05-07 | May | Durham Bulls | Home | L | 6-7 | boxscore | 5,223 | 3:00 | 16-13 | Sahlen Field | Buffalo,New York |
| 2022-05-08 | May | Durham Bulls | Home | L | 2-6 | boxscore | 5,758 | 2:30 | 16-14 | Sahlen Field | Buffalo,New York |
| 2022-05-10 | May | Lehigh Valley IronPigs | Vis | W | 14-3 | boxscore | 5,722 | 3:02 | 17-14 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-05-11 | May | Lehigh Valley IronPigs | Vis | W | 4-3 | boxscore | 4,998 | 2:30 | 18-14 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-05-12 | May | Lehigh Valley IronPigs | Vis | L | 2-6 | boxscore | 6,785 | 2:48 | 18-15 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-05-13 | May | Lehigh Valley IronPigs | Vis | W | 3-2 | boxscore | 10,100 | 2:52 | 19-15 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-05-15 | May | Lehigh Valley IronPigs | Vis | W | 10-5 | boxscore | 0 | 2:39 | 20-15 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-05-15 | May | Lehigh Valley IronPigs | Vis | L | 5-7 | boxscore | 8,891 | 2:11 | 20-16 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-05-17 | May | Syracuse Mets | Home | W | 9-3 | boxscore | 4,136 | 2:25 | 21-16 | Sahlen Field | Buffalo,New York |
| 2022-05-19 | May | Syracuse Mets | Home | L | 0-1 | boxscore | 0 | 2:01 | 21-17 | Sahlen Field | Buffalo,New York |
| 2022-05-19 | May | Syracuse Mets | Home | W | 4-1 | boxscore | 4,159 | 1:52 | 22-17 | Sahlen Field | Buffalo,New York |
| 2022-05-20 | May | Syracuse Mets | Home | W | 2-0 | boxscore | 7,545 | 1:53 | 23-17 | Sahlen Field | Buffalo,New York |
| 2022-05-21 | May | Syracuse Mets | Home | W | 12-11 | boxscore | 4,965 | 3:28 | 24-17 | Sahlen Field | Buffalo,New York |
| 2022-05-24 | May | Columbus Clippers | Vis | W | 1-0 | boxscore | 9,142 | 2:12 | 25-17 | Huntington Park | Columbus,Ohio |
| 2022-05-25 | May | Columbus Clippers | Vis | W | 5-4 | boxscore | 5,035 | 2:43 | 26-17 | Huntington Park | Columbus,Ohio |
| 2022-05-27 | May | Columbus Clippers | Vis | W | 5-3 | boxscore | 5,279 | 2:36 | 27-17 | Huntington Park | Columbus,Ohio |
| 2022-05-28 | May | Columbus Clippers | Vis | W | 4-2 | boxscore | 0 | 2:14 | 28-17 | Huntington Park | Columbus,Ohio |
| 2022-05-28 | May | Columbus Clippers | Vis | L | 3-4 | boxscore | 10,100 | 2:06 | 28-18 | Huntington Park | Columbus,Ohio |
| 2022-05-29 | May | Columbus Clippers | Vis | W | 7-5 | boxscore | 7,266 | 2:33 | 29-18 | Huntington Park | Columbus,Ohio |
| 2022-05-30 | May | Rochester Red Wings | Vis | W | 7-5 | boxscore | 8,978 | 2:47 | 30-18 | Frontier Field | Rochester,New York |
| 2022-06-02 | June | Rochester Red Wings | Vis | L | 1-6 | boxscore | 5,249 | 2:28 | 30-19 | Frontier Field | Rochester,New York |
| 2022-06-03 | June | Rochester Red Wings | Vis | L | 1-2 | boxscore | 10,510 | 2:21 | 30-20 | Frontier Field | Rochester,New York |
| 2022-06-04 | June | Rochester Red Wings | Vis | L | 1-5 | boxscore | 0 | 1:47 | 30-21 | Frontier Field | Rochester,New York |
| 2022-06-04 | June | Rochester Red Wings | Vis | W | 13-0 | boxscore | 10,635 | 2:15 | 31-21 | Frontier Field | Rochester,New York |
| 2022-06-05 | June | Rochester Red Wings | Vis | L | 2-11 | boxscore | 8,948 | 2:33 | 31-22 | Frontier Field | Rochester,New York |
| 2022-06-08 | June | Worcester Red Sox | Home | L | 1-3 | boxscore | 0 | 2:10 | 31-23 | Sahlen Field | Buffalo,New York |
| 2022-06-08 | June | Worcester Red Sox | Home | L | 0-9 | boxscore | 5,773 | 1:57 | 31-24 | Sahlen Field | Buffalo,New York |
| 2022-06-09 | June | Worcester Red Sox | Home | L | 0-6 | boxscore | 4,652 | 2:36 | 31-25 | Sahlen Field | Buffalo,New York |
| 2022-06-10 | June | Worcester Red Sox | Home | W | 4-1 | boxscore | 10,228 | 2:22 | 32-25 | Sahlen Field | Buffalo,New York |
| 2022-06-11 | June | Worcester Red Sox | Home | W | 4-1 | boxscore | 15,490 | 2:33 | 33-25 | Sahlen Field | Buffalo,New York |
| 2022-06-12 | June | Worcester Red Sox | Home | L | 3-4 | boxscore | 6,555 | 2:37 | 33-26 | Sahlen Field | Buffalo,New York |
| 2022-06-14 | June | Lehigh Valley IronPigs | Vis | W | 3-2 | boxscore | 6,848 | 2:42 | 34-26 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-06-15 | June | Lehigh Valley IronPigs | Vis | W | 8-4 | boxscore | 5,813 | 2:42 | 35-26 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-06-16 | June | Lehigh Valley IronPigs | Vis | W | 3-2 | boxscore | 6,324 | 2:30 | 36-26 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-06-17 | June | Lehigh Valley IronPigs | Vis | L | 4-5 | boxscore | 8,644 | 2:44 | 36-27 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-06-18 | June | Lehigh Valley IronPigs | Vis | W | 3-2 | boxscore | 10,100 | 3:03 | 37-27 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-06-19 | June | Lehigh Valley IronPigs | Vis | L | 2-5 | boxscore | 10,100 | 2:39 | 37-28 | Coca-Cola Park | Allentown,Pennsylvania |
| 2022-06-21 | June | St. Paul Saints | Home | W | 8-7 | boxscore | 6,061 | 2:53 | 38-28 | Sahlen Field | Buffalo,New York |
| 2022-06-22 | June | St. Paul Saints | Home | W | 3-2 | boxscore | 5,124 | 2:21 | 39-28 | Sahlen Field | Buffalo,New York |
| 2022-06-23 | June | St. Paul Saints | Home | L | 1-7 | boxscore | 6,687 | 2:37 | 39-29 | Sahlen Field | Buffalo,New York |
| 2022-06-24 | June | St. Paul Saints | Home | W | 5-4 | boxscore | 9,246 | 2:38 | 40-29 | Sahlen Field | Buffalo,New York |
| 2022-06-25 | June | St. Paul Saints | Home | L | 4-7 | boxscore | 6,344 | 3:11 | 40-30 | Sahlen Field | Buffalo,New York |
| 2022-06-26 | June | St. Paul Saints | Home | W | 2-1 | boxscore | 6,453 | 2:12 | 41-30 | Sahlen Field | Buffalo,New York |
| 2022-06-28 | June | Scranton/Wilkes-Barre RailRiders | Vis | L | 4-5 | boxscore | 4,274 | 2:54 | 41-31 | PNC Field | Moosic,Pennsylvania |
| 2022-06-29 | June | Scranton/Wilkes-Barre RailRiders | Vis | L | 3-5 | boxscore | 4,811 | 2:31 | 41-32 | PNC Field | Moosic,Pennsylvania |
| 2022-06-30 | June | Scranton/Wilkes-Barre RailRiders | Vis | L | 1-8 | boxscore | 4,403 | 2:43 | 41-33 | PNC Field | Moosic,Pennsylvania |
| 2022-07-01 | July | Scranton/Wilkes-Barre RailRiders | Vis | L | 1-8 | boxscore | 5,267 | 2:22 | 41-34 | PNC Field | Moosic,Pennsylvania |
| 2022-07-02 | July | Scranton/Wilkes-Barre RailRiders | Vis | L | 3-4 | boxscore | 8,021 | 2:36 | 41-35 | PNC Field | Moosic,Pennsylvania |
| 2022-07-03 | July | Scranton/Wilkes-Barre RailRiders | Vis | L | 1-5 | boxscore | 3,952 | 2:44 | 41-36 | PNC Field | Moosic,Pennsylvania |
| 2022-07-04 | July | Syracuse Mets | Home | L | 3-4 | boxscore | 14,836 | 2:37 | 41-37 | Sahlen Field | Buffalo,New York |
| 2022-07-06 | July | Syracuse Mets | Home | L | 4-9 | boxscore | 0 | 2:13 | 41-38 | Sahlen Field | Buffalo,New York |
| 2022-07-06 | July | Syracuse Mets | Home | W | 6-4 | boxscore | 6,912 | 2:12 | 42-38 | Sahlen Field | Buffalo,New York |
| 2022-07-07 | July | Syracuse Mets | Home | L | 2-3 | boxscore | 5,860 | 2:28 | 42-39 | Sahlen Field | Buffalo,New York |
| 2022-07-08 | July | Syracuse Mets | Home | W | 6-1 | boxscore | 10,758 | 2:33 | 43-39 | Sahlen Field | Buffalo,New York |
| 2022-07-09 | July | Syracuse Mets | Home | L | 2-4 | boxscore | 7,179 | 2:50 | 43-40 | Sahlen Field | Buffalo,New York |
| 2022-07-10 | July | Syracuse Mets | Home | L | 2-4 | boxscore | 8,422 | 2:32 | 43-41 | Sahlen Field | Buffalo,New York |
| 2022-07-12 | July | Iowa Cubs | Vis | L | 2-8 | boxscore | 5,941 | 2:21 | 43-42 | Principal Park | Des Moines,Iowa |
| 2022-07-13 | July | Iowa Cubs | Vis | W | 8-4 | boxscore | 5,027 | 2:55 | 44-42 | Principal Park | Des Moines,Iowa |
| 2022-07-14 | July | Iowa Cubs | Vis | W | 5-4 | boxscore | 5,830 | 3:30 | 45-42 | Principal Park | Des Moines,Iowa |
| 2022-07-15 | July | Iowa Cubs | Vis | L | 1-3 | boxscore | 10,558 | 2:17 | 45-43 | Principal Park | Des Moines,Iowa |
| 2022-07-16 | July | Iowa Cubs | Vis | W | 6-5 | boxscore | 8,950 | 2:55 | 46-43 | Principal Park | Des Moines,Iowa |
| 2022-07-17 | July | Iowa Cubs | Vis | L | 4-6 | boxscore | 6,570 | 2:42 | 46-44 | Principal Park | Des Moines,Iowa |
| 2022-07-22 | July | Rochester Red Wings | Home | W | 3-0 | boxscore | 13,741 | 2:33 | 47-44 | Sahlen Field | Buffalo,New York |
| 2022-07-23 | July | Rochester Red Wings | Home | W | 10-9 | boxscore | 8,821 | 3:30 | 48-44 | Sahlen Field | Buffalo,New York |
| 2022-07-24 | July | Rochester Red Wings | Home | W | 1-0 | boxscore | 5,947 | 2:11 | 49-44 | Sahlen Field | Buffalo,New York |
| 2022-07-26 | July | Worcester Red Sox | Home | L | 1-2 | boxscore | 7,425 | 2:30 | 49-45 | Sahlen Field | Buffalo,New York |
| 2022-07-27 | July | Worcester Red Sox | Home | W | 7-2 | boxscore | 6,683 | 2:43 | 50-45 | Sahlen Field | Buffalo,New York |
| 2022-07-28 | July | Worcester Red Sox | Home | L | 1-3 | boxscore | 7,752 | 2:31 | 50-46 | Sahlen Field | Buffalo,New York |
| 2022-07-29 | July | Worcester Red Sox | Home | W | 7-6 | boxscore | 11,249 | 2:36 | 51-46 | Sahlen Field | Buffalo,New York |
| 2022-07-30 | July | Worcester Red Sox | Home | W | 5-3 | boxscore | 7,196 | 2:40 | 52-46 | Sahlen Field | Buffalo,New York |
| 2022-07-31 | July | Worcester Red Sox | Home | L | 1-4 | boxscore | 7,344 | 2:35 | 52-47 | Sahlen Field | Buffalo,New York |
| 2022-08-02 | August | Scranton/Wilkes-Barre RailRiders | Vis | W | 4-0 | boxscore | 4,054 | 2:53 | 53-47 | PNC Field | Moosic,Pennsylvania |
| 2022-08-03 | August | Scranton/Wilkes-Barre RailRiders | Vis | L | 2-5 | boxscore | 3,815 | 2:46 | 53-48 | PNC Field | Moosic,Pennsylvania |
| 2022-08-04 | August | Scranton/Wilkes-Barre RailRiders | Vis | W | 7-4 | boxscore | 4,122 | 2:34 | 54-48 | PNC Field | Moosic,Pennsylvania |
| 2022-08-05 | August | Scranton/Wilkes-Barre RailRiders | Vis | L | 0-5 | boxscore | 5,273 | 2:34 | 54-49 | PNC Field | Moosic,Pennsylvania |
| 2022-08-06 | August | Scranton/Wilkes-Barre RailRiders | Vis | L | 1-5 | boxscore | 6,887 | 2:15 | 54-50 | PNC Field | Moosic,Pennsylvania |
| 2022-08-09 | August | Syracuse Mets | Vis | W | 4-3 | boxscore | 3,425 | 2:30 | 56-50 | NBT Bank Stadium | Syracuse,New York |
| 2022-08-10 | August | Syracuse Mets | Vis | W | 10-3 | boxscore | 3,281 | 2:33 | 57-50 | NBT Bank Stadium | Syracuse,New York |
| 2022-08-11 | August | Syracuse Mets | Vis | L | 5-6 | boxscore | 6,117 | 2:50 | 57-51 | NBT Bank Stadium | Syracuse,New York |
| 2022-08-12 | August | Syracuse Mets | Vis | W | 3-1 | boxscore | 6,175 | 2:45 | 58-51 | NBT Bank Stadium | Syracuse,New York |
| 2022-08-13 | August | Syracuse Mets | Vis | W | 8-1 | boxscore | 5,022 | 2:57 | 59-51 | NBT Bank Stadium | Syracuse,New York |
| 2022-08-14 | August | Syracuse Mets | Vis | W | 2-0 | boxscore | 3,302 | 2:38 | 60-51 | NBT Bank Stadium | Syracuse,New York |
| 2022-08-16 | August | Lehigh Valley IronPigs | Home | W | 5-2 | boxscore | 7,055 | 2:26 | 61-51 | Sahlen Field | Buffalo,New York |
| 2022-08-17 | August | Lehigh Valley IronPigs | Home | L | 4-15 | boxscore | 6,471 | 3:19 | 61-52 | Sahlen Field | Buffalo,New York |
| 2022-08-18 | August | Lehigh Valley IronPigs | Home | W | 5-4 | boxscore | 7,122 | 2:24 | 62-52 | Sahlen Field | Buffalo,New York |
| 2022-08-19 | August | Lehigh Valley IronPigs | Home | L | 7-8 | boxscore | 9,452 | 2:49 | 62-53 | Sahlen Field | Buffalo,New York |
| 2022-08-20 | August | Lehigh Valley IronPigs | Home | W | 10-1 | boxscore | 8,957 | 2:53 | 63-53 | Sahlen Field | Buffalo,New York |
| 2022-08-21 | August | Lehigh Valley IronPigs | Home | L | 3-5 | boxscore | 6,743 | 3:05 | 63-54 | Sahlen Field | Buffalo,New York |
| 2022-08-23 | August | Columbus Clippers | Home | L | 10-11 | boxscore | 6,536 | 3:34 | 63-55 | Sahlen Field | Buffalo,New York |
| 2022-08-24 | August | Columbus Clippers | Home | W | 6-2 | boxscore | 7,099 | 2:16 | 64-55 | Sahlen Field | Buffalo,New York |
| 2022-08-25 | August | Columbus Clippers | Home | L | 6-9 | boxscore | 6,218 | 2:48 | 64-56 | Sahlen Field | Buffalo,New York |
| 2022-08-26 | August | Columbus Clippers | Home | W | 6-0 | boxscore | 9,332 | 2:44 | 65-56 | Sahlen Field | Buffalo,New York |
| 2022-08-27 | August | Columbus Clippers | Home | L | 2-8 | boxscore | 11,311 | 3:03 | 65-57 | Sahlen Field | Buffalo,New York |
| 2022-08-28 | August | Columbus Clippers | Home | L | 3-14 | boxscore | 7,145 | 3:02 | 65-58 | Sahlen Field | Buffalo,New York |
| 2022-08-30 | August | Worcester Red Sox | Vis | W | 14-3 | boxscore | 5,144 | 3:25 | 66-58 | Polar Park | Worcester,Massachusetts |
| 2022-08-31 | August | Worcester Red Sox | Vis | L | 1-9 | boxscore | 6,275 | 2:39 | 66-59 | Polar Park | Worcester,Massachusetts |
| 2022-09-01 | September | Worcester Red Sox | Vis | L | 3-4 | boxscore | 5,896 | 2:21 | 66-60 | Polar Park | Worcester,Massachusetts |
| 2022-09-02 | September | Worcester Red Sox | Vis | W | 10-8 | boxscore | 7,330 | 3:14 | 67-60 | Polar Park | Worcester,Massachusetts |
| 2022-09-03 | September | Worcester Red Sox | Vis | L | 0-9 | boxscore | 7,293 | 2:49 | 67-61 | Polar Park | Worcester,Massachusetts |
| 2022-09-04 | September | Worcester Red Sox | Vis | L | 2-5 | boxscore | 7,075 | 2:21 | 67-62 | Polar Park | Worcester,Massachusetts |
| 2022-09-07 | September | Gwinnett Stripers | Home | W | 10-7 | boxscore | 4,153 | 2:25 | 68-62 | Sahlen Field | Buffalo,New York |
| 2022-09-08 | September | Gwinnett Stripers | Home | W | 6-2 | boxscore | 4,917 | 2:11 | 69-62 | Sahlen Field | Buffalo,New York |
| 2022-09-09 | September | Gwinnett Stripers | Home | W | 3-1 | boxscore | 0 | 1:46 | 70-62 | Sahlen Field | Buffalo,New York |
| 2022-09-09 | September | Gwinnett Stripers | Home | L | 3-4 | boxscore | 7,998 | 1:56 | 70-63 | Sahlen Field | Buffalo,New York |
| 2022-09-10 | September | Gwinnett Stripers | Home | L | 1-4 | boxscore | 6,347 | 2:54 | 70-64 | Sahlen Field | Buffalo,New York |
| 2022-09-13 | September | Syracuse Mets | Vis | W | 15-8 | boxscore | 2,308 | 3:28 | 71-64 | NBT Bank Stadium | Syracuse,New York |
| 2022-09-14 | September | Syracuse Mets | Vis | W | 2-1 | boxscore | 5,307 | 2:56 | 72-64 | NBT Bank Stadium | Syracuse,New York |
| 2022-09-15 | September | Syracuse Mets | Vis | W | 12-7 | boxscore | 5,369 | 3:19 | 73-64 | NBT Bank Stadium | Syracuse,New York |
| 2022-09-16 | September | Syracuse Mets | Vis | L | 3-5 | boxscore | 4,010 | 2:50 | 73-65 | NBT Bank Stadium | Syracuse,New York |
| 2022-09-17 | September | Syracuse Mets | Vis | L | 3-8 | boxscore | 5,044 | 2:50 | 73-66 | NBT Bank Stadium | Syracuse,New York |
| 2022-09-18 | September | Syracuse Mets | Vis | L | 8-9 | boxscore | 3,036 | 2:29 | 73-67 | NBT Bank Stadium | Syracuse,New York |
| 2022-09-20 | September | Rochester Red Wings | Home | W | 3-2 | boxscore | 5,266 | 2:47 | 74-67 | Sahlen Field | Buffalo,New York |
| 2022-09-21 | September | Rochester Red Wings | Home | L | 3-7 | boxscore | 4,112 | 2:41 | 74-68 | Sahlen Field | Buffalo,New York |
| 2022-09-22 | September | Rochester Red Wings | Home | W | 10-2 | boxscore | 4,285 | 2:57 | 75-68 | Sahlen Field | Buffalo,New York |
| 2022-09-23 | September | Rochester Red Wings | Home | L | 2-5 | boxscore | 9,668 | 2:45 | 75-69 | Sahlen Field | Buffalo,New York |
| 2022-09-24 | September | Rochester Red Wings | Home | L | 4-7 | boxscore | 7,194 | 2:44 | 75-70 | Sahlen Field | Buffalo,New York |
| 2022-09-26 | September | Scranton/Wilkes-Barre RailRiders | Vis | W | 5-4 | boxscore | 5,255 | 2:45 | 75-71 | PNC Field | Moosic,Pennsylvania |
| 2022-09-26 | September | Scranton/Wilkes-Barre RailRiders | Vis | L | 7-8 | boxscore | 2,608 | 3:39 | 75-71 | PNC Field | Moosic,Pennsylvania |
| 2022-09-27 | September | Scranton/Wilkes-Barre RailRiders | Vis | W | 8-1 | boxscore | 2,842 | 2:37 | 76-71 | PNC Field | Moosic,Pennsylvania |
| 2022-09-28 | September | Scranton/Wilkes-Barre RailRiders | Vis | L | 0-3 | boxscore | 3,149 | 2:33 | 76-72 | PNC Field | Moosic,Pennsylvania |
| 148 record(s) |