| 1981 | ATL | Atlanta Braves | MLB-NL | MLB | team page | 106 | 50 | 56 | -- | 395 | 416 | -21 | 0 | 8 | Bobby Cox | Atlanta-Fulton County Stadium | dnq |
| 1981 | ATL | Richmond Braves | IL | AAA | team page | 139 | 83 | 56 | 5.0 | 605 | 546 | 59 | 2 | 2 | Eddie Haas | Parker Field | Lost in Finals |
| 1981 | ATL | Savannah Braves | Sou | AA | team page | 140 | 70 | 70 | 8.0 | 616 | 622 | -6 | 3 | 6 | Andy Gilbert | Grayson Stadium | Lost in Semi-Finals |
| 1981 | ATL | Durham Bulls | Caro | A+ | team page | 138 | 70 | 68 | 1.0 | 652 | 655 | -3 | 4 | 5 | Al Gallagher | Durham Athletic Park | dnq |
| 1981 | ATL | Anderson Braves | SAL | A | team page | 143 | 57 | 86 | 21.5 | 615 | 776 | -161 | 5 | 10 | Sonny Jackson | Anderson Memorial Stadium | dnq |
| 1981 | ATL | Gulf Coast Braves | GCL | Rk | team page | 62 | 28 | 34 | 15.0 | 227 | 258 | -31 | 8 | 8 | Pedro Gonzalez | West Palm Beach Municipal Stadium | dnq |
| 1981 | BAL | Baltimore Orioles | MLB-AL | MLB | team page | 105 | 59 | 46 | -- | 429 | 437 | -8 | 0 | 3 | Earl Weaver | Memorial Stadium | dnq |
| 1981 | BAL | Rochester Red Wings | IL | AAA | team page | 139 | 69 | 70 | 19.0 | 628 | 571 | 57 | 4 | 4 | Doc Edwards | Silver Stadium | Lost in Semi-Finals |
| 1981 | BAL | Charlotte O's | Sou | AA | team page | 143 | 74 | 69 | 5.5 | 703 | 668 | 35 | 2 | 4 | Mark Wiley | Crockett Park | dnq |
| 1981 | BAL | Miami Orioles | FSL | A+ | team page | 136 | 44 | 92 | 38.0 | 471 | 729 | -258 | 5 | 10 | Minnie Mendoza | Miami Stadium | dnq |
| 1981 | BAL | Bluefield Orioles | App | Rk | team page | 70 | 36 | 34 | 10.0 | 384 | 365 | 19 | 3 | 4 | Lance Nichols | Bowen Field at Peters Park | dnq |
| 1981 | BOS | Boston Red Sox | MLB-AL | MLB | team page | 108 | 59 | 49 | -- | 519 | 481 | 38 | 0 | 6 | Ralph Houk | Fenway Park | dnq |
| 1981 | BOS | Pawtucket Red Sox | IL | AAA | team page | 140 | 67 | 73 | 21.5 | 535 | 551 | -16 | 6 | 6 | Joe Morgan | McCoy Stadium | dnq |
| 1981 | BOS | Bristol Red Sox | East | AA | team page | 137 | 79 | 58 | -- | 621 | 504 | 117 | 1 | 2 | Tony Torchia | Muzzy Field | League Champions |
| 1981 | BOS | Winston-Salem Red Sox | Caro | A+ | team page | 139 | 72 | 67 | 0.5 | 708 | 762 | -54 | 2 | 2 | Buddy Hunter | Ernie Shore Field | dnq |
| 1981 | BOS | Winter Haven Red Sox | FSL | A+ | team page | 139 | 62 | 77 | 20.0 | 585 | 636 | -51 | 5 | 9 | Rac Slider | Chain of Lakes Park | dnq |
| 1981 | BOS | Elmira Pioneers | NYPL | A- | team page | 73 | 25 | 48 | 23.0 | 338 | 459 | -121 | 4 | 7 | Dick Berardino | Dunn Field | dnq |
| 1981 | CAL | California Angels | MLB-AL | MLB | team page | 110 | 51 | 59 | -- | 476 | 453 | 23 | 0 | 11 | Gene Mauch, Jim Fregosi | Anaheim Stadium | dnq |
| 1981 | CAL | Salt Lake Gulls | PCL | AAA | team page | 134 | 63 | 71 | 32.0 | 770 | 852 | -82 | 3 | 6 | Moose Stubing | Derks Field | dnq |
| 1981 | CAL | Holyoke Millers | East | AA | team page | 138 | 68 | 70 | 16.5 | 626 | 611 | 15 | 2 | 5 | Jim Saul | Mackenzie Stadium | dnq |
| 1981 | CAL | Redwood Pioneers | Calif | A+ | team page | 140 | 66 | 74 | 21.0 | 656 | 693 | -37 | 6 | 6 | Chris Cannizzaro | Rohnert Park Stadium | dnq |
| 1981 | CAL | Salem Senators | Nwst | A- | team page | 70 | 36 | 34 | 6.0 | 370 | 361 | 9 | 2 | 3 | Rick Ingalls | Chemeketa Community College Field | dnq |
| 1981 | CAL | Idaho Falls Angels | Pio | Rk | team page | 70 | 27 | 43 | 12.0 | 378 | 446 | -68 | 3 | 7 | Joe Maddon | McDermott Field | dnq |
| 1981 | CHN | Chicago Cubs | MLB-NL | MLB | team page | 103 | 38 | 65 | -- | 370 | 483 | -113 | 0 | 12 | Joey Amalfitano | Wrigley Field | dnq |
| 1981 | CHN | Iowa Oaks | Amer | AAA | team page | 135 | 53 | 82 | 19.5 | 567 | 703 | -136 | 4 | 8 | Roy Hartsfield, Randy Hundley | Sec Taylor Stadium | dnq |
| 1981 | CHN | Midland Cubs | Tex | AA | team page | 67 | 36 | 31 | -- | 755 | 770 | -15 | 0 | 4 | George Enright, Roy Hartsfield | Cubs Stadium | dnq |
| 1981 | CHN | Quad Cities Cubs | Midw | A | team page | 135 | 77 | 58 | -- | 544 | 547 | -3 | 1 | 3 | Rich Morales | John O'Donnell Stadium | Lost in Finals |
| 1981 | CHN | Geneva Cubs | NYPL | A- | team page | 75 | 41 | 34 | 7.5 | 414 | 376 | 38 | 3 | 5 | Bob Hartsfield | McDonough Park | dnq |
| 1981 | CHN | Gulf Coast Cubs | GCL | Rk | team page | 63 | 25 | 38 | 18.5 | 216 | 302 | -86 | 10 | 11 | Hugh Yancy | Sarasota | dnq |
| 1981 | CHA | Chicago White Sox | MLB-AL | MLB | team page | 106 | 54 | 52 | -- | 476 | 423 | 53 | 0 | 8 | Tony La Russa | Comiskey Park | dnq |
| 1981 | CHA | Edmonton Trappers | PCL | AAA | team page | 136 | 62 | 74 | 14.5 | 667 | 733 | -66 | 4 | 7 | Gordy Lund | John Ducey Park | dnq |
| 1981 | CHA | Glens Falls White Sox | East | AA | team page | 135 | 83 | 52 | -- | 756 | 641 | 115 | 1 | 1 | Jim Mahoney | East Field Stadium | Lost in Finals |
| 1981 | CHA | Appleton Foxes | Midw | A | team page | 134 | 54 | 80 | 31.0 | 492 | 584 | -92 | 4 | 6 | Sam Ewing | Goodland Field | dnq |
| 1981 | CHA | Gulf Coast White Sox | GCL | Rk | team page | 64 | 41 | 23 | 3.0 | 316 | 235 | 81 | 2 | 2 | John Boles | Payne Park | dnq |
| 1981 | CIN | Cincinnati Reds | MLB-NL | MLB | team page | 108 | 66 | 42 | -- | 464 | 440 | 24 | 0 | 1 | John McNamara | Riverfront Stadium | dnq |
| 1981 | CIN | Indianapolis Indians | Amer | AAA | team page | 136 | 62 | 74 | 11.0 | 575 | 520 | 55 | 3 | 7 | Jim Beauchamp | Bush Stadium | dnq |
| 1981 | CIN | Waterbury Reds | East | AA | team page | 138 | 55 | 83 | 24.5 | 524 | 690 | -166 | 4 | 8 | George Scherger | Municipal Stadium | dnq |
| 1981 | CIN | Tampa Tarpons | FSL | A+ | team page | 133 | 79 | 54 | -- | 576 | 522 | 54 | 1 | 2 | Jim Lett | Al Lopez Field | Lost in Semi-Finals |
| 1981 | CIN | Cedar Rapids Reds | Midw | A | team page | 133 | 65 | 68 | 11.0 | 484 | 540 | -56 | 2 | 5 | Randy Davidson | Veterans Field | Lost in Semi-Finals |
| 1981 | CIN | Eugene Emeralds | Nwst | A- | team page | 70 | 33 | 37 | 9.0 | 395 | 370 | 25 | 3 | 4 | Bill Bryk | Civic Stadium | dnq |
| 1981 | CIN | Billings Mustangs | Pio | Rk | team page | 70 | 30 | 40 | 9.0 | 377 | 411 | -34 | 2 | 6 | Jim Hoff | Cobb Field | dnq |
| 1981 | CLE | Cleveland Indians | MLB-AL | MLB | team page | 103 | 52 | 51 | -- | 431 | 442 | -11 | 0 | 9 | Dave Garcia | Cleveland Stadium | dnq |
| 1981 | CLE | Charleston Charlies | IL | AAA | team page | 139 | 67 | 72 | 21.0 | 651 | 631 | 20 | 5 | 5 | Cal Emery, Frank Lucchesi | Walt Powell Park | dnq |
| 1981 | CLE | Chattanooga Lookouts | Sou | AA | team page | 142 | 67 | 75 | 13.5 | 661 | 734 | -73 | 4 | 7 | Woody Smith | Engel Stadium | dnq |
| 1981 | CLE | Waterloo Indians | Midw | A | team page | 136 | 81 | 55 | 5.0 | 695 | 600 | 95 | 2 | 2 | Gomer Hodge | Municipal Stadium | Lost in Semi-Finals |
| 1981 | CLE | Batavia Trojans | NYPL | A- | team page | 75 | 16 | 59 | 32.5 | 282 | 539 | -257 | 4 | 8 | Dave Oliver | Dwyer Stadium | dnq |
| 1981 | DET | Detroit Tigers | MLB-AL | MLB | team page | 109 | 60 | 49 | -- | 427 | 404 | 23 | 0 | 5 | Sparky Anderson | Tiger Stadium | dnq |
| 1981 | DET | Evansville Triplets | Amer | AAA | team page | 136 | 73 | 63 | -- | 624 | 585 | 39 | 1 | 3 | Jim Leyland | Bosse Field | dnq |
| 1981 | DET | Birmingham Barons | Sou | AA | team page | 141 | 71 | 70 | 9.0 | 691 | 648 | 43 | 3 | 5 | Roy Majtyka | Hoover Metropolitan Stadium | dnq |
| 1981 | DET | Lakeland Tigers | FSL | A+ | team page | 133 | 69 | 64 | 10.0 | 584 | 530 | 54 | 2 | 5 | Ted Brazell | Joker Marchant Stadium | dnq |
| 1981 | DET | Macon Peaches | SAL | A | team page | 141 | 62 | 79 | 15.5 | 647 | 670 | -23 | 4 | 8 | Tom Kotchman | Luther Williams Field | dnq |
| 1981 | DET | Bristol Tigers | App | Rk | team page | 70 | 29 | 41 | 17.0 | 326 | 396 | -70 | 5 | 5 | Joe Lewis | Devault Memorial Stadium | dnq |
| 1981 | HOU | Houston Astros | MLB-NL | MLB | team page | 110 | 61 | 49 | -- | 394 | 331 | 63 | 0 | 5 | Bill Virdon | Astrodome | Lost in 1st Round (Dodgers) |
| 1981 | HOU | Tucson Toros | PCL | AAA | team page | 139 | 57 | 82 | 40.5 | 746 | 777 | -31 | 4 | 9 | Jimmy Johnson | Hi Corbett Field | dnq |
| 1981 | HOU | Columbus Astros | Sou | AA | team page | 141 | 63 | 78 | 15.5 | 660 | 750 | -90 | 5 | 9 | Matt Galante | Golden Park | dnq |
| 1981 | HOU | Daytona Astros | FSL | A+ | team page | 135 | 68 | 67 | 12.0 | 644 | 570 | 74 | 4 | 6 | Carlos Alfonso | Jackie Robinson Ballpark | League Champions |
| 1981 | HOU | Gulf Coast Astros Blue | GCL | Rk | team page | 60 | 22 | 38 | 20.0 | 210 | 325 | -115 | 12 | 12 | Eric Swanson | Saraosta | dnq |
| 1981 | HOU | Gulf Coast Astros Orange | GCL | Rk | team page | 61 | 33 | 28 | 9.5 | 306 | 246 | 60 | 4 | 4 | Lyle Olsen | Saraosta | dnq |
| 1981 | KCA | Kansas City Royals | MLB-AL | MLB | team page | 103 | 50 | 53 | -- | 397 | 405 | -8 | 0 | 10 | Jim Frey, Dick Howser | Royals Stadium | Lost in 1st Round (Athletics) |
| 1981 | KCA | Omaha Royals | Amer | AAA | team page | 136 | 79 | 57 | -- | 617 | 552 | 65 | 1 | 1 | Joe Sparks | Johnny Rosenblatt Stadium | Lost in Finals |
| 1981 | KCA | Jacksonville Suns | Sou | AA | team page | 142 | 65 | 77 | 14.0 | 566 | 652 | -86 | 4 | 8 | Gene Lamont | Sam W. Wolfson Baseball Park | dnq |
| 1981 | KCA | Fort Myers Royals | FSL | A+ | team page | 130 | 72 | 58 | 7.0 | 578 | 465 | 113 | 2 | 3 | Brian Murphy | Terry Park Ballfield | Lost in Finals |
| 1981 | KCA | Charleston (sc) Royals | SAL | A | team page | 142 | 75 | 67 | 3.0 | 632 | 612 | 20 | 2 | 3 | Rick Mathews | College Park | dnq |
| 1981 | KCA | Gulf Coast Royals Blue | GCL | Rk | team page | 63 | 35 | 28 | 8.5 | 333 | 237 | 96 | 3 | 3 | Joe Jones | Baseball City Stadium | dnq |
| 1981 | KCA | Gulf Coast Royals Gold | GCL | Rk | team page | 64 | 44 | 20 | -- | 297 | 224 | 73 | 1 | 1 | Roy Tanner | Baseball City Stadium | League Champions |
| 1981 | LAN | Los Angeles Dodgers | MLB-NL | MLB | team page | 110 | 63 | 47 | -- | 450 | 356 | 94 | 0 | 3 | Tommy Lasorda | Dodger Stadium | Won World Series (Yankees) |
| 1981 | LAN | Albuquerque Dukes | PCL | AAA | team page | 132 | 94 | 38 | -- | 877 | 604 | 273 | 1 | 1 | Del Crandall | Albuquerque Sports Stadium | League Champions |
| 1981 | LAN | San Antonio Dodgers | Tex | AA | team page | 68 | 40 | 28 | -- | 775 | 682 | 93 | 0 | 2 | Don LeJohn | V.J. Keefe Memorial Stadium | Lost in Finals |
| 1981 | LAN | Lodi Dodgers | Calif | A+ | team page | 140 | 73 | 67 | 14.0 | 798 | 772 | 26 | 3 | 3 | Terry Collins | Lawrence Park | League Champions |
| 1981 | LAN | Vero Beach Dodgers | FSL | A+ | team page | 136 | 63 | 73 | 19.0 | 597 | 695 | -98 | 4 | 8 | Paul Popovich, John Shoemaker, Stan Wasiak | Holman Stadium | dnq |
| 1981 | LAN | Lethbridge Dodgers | Pio | Rk | team page | 70 | 43 | 27 | 3.0 | 403 | 340 | 63 | 2 | 2 | Gary LaRocque | Henderson Stadium | dnq |
| 1981 | MIL | Milwaukee Brewers | MLB-AL | MLB | team page | 109 | 62 | 47 | -- | 493 | 459 | 34 | 0 | 2 | Buck Rodgers | County Stadium | Lost ALCS (Yankees) |
| 1981 | MIL | Vancouver Canadians | PCL | AAA | team page | 132 | 56 | 76 | 18.5 | 470 | 611 | -141 | 6 | 8 | Lee Sigman | Nat Bailey Stadium | dnq |
| 1981 | MIL | El Paso Diablos | Tex | AA | team page | 66 | 28 | 38 | -- | 712 | 736 | -24 | 0 | 7 | Tony Muser | Dudley Field | dnq |
| 1981 | MIL | Stockton Ports | Calif | A+ | team page | 139 | 68 | 71 | 18.5 | 644 | 641 | 3 | 4 | 4 | Duane Espy | Billy Hebert Field | Lost in Semi-Finals |
| 1981 | MIL | Burlington Bees | Midw | A | team page | 135 | 54 | 81 | 23.0 | 553 | 707 | -154 | 3 | 7 | Terry Bevington | Community Field | dnq |
| 1981 | MIL | Butte Copper Kings | Pio | Rk | team page | 70 | 39 | 31 | -- | 460 | 405 | 55 | 1 | 3 | Ken Richardson | Alumni Coliseum | League Champions |
| 1981 | MIN | Minnesota Twins | MLB-AL | MLB | team page | 109 | 41 | 68 | -- | 378 | 486 | -108 | 0 | 13 | Billy Gardner, Johnny Goryl | Metropolitan Stadium | dnq |
| 1981 | MIN | Toledo Mud Hens | IL | AAA | team page | 140 | 53 | 87 | 35.5 | 504 | 678 | -174 | 8 | 8 | Cal Ermer | Lucas County Stadium | dnq |
| 1981 | MIN | Orlando Twins | Sou | AA | team page | 142 | 79 | 63 | -- | 750 | 671 | 79 | 1 | 2 | Tom Kelly | Tinker Field | League Champions |
| 1981 | MIN | Visalia Oaks | Calif | A+ | team page | 140 | 87 | 53 | -- | 888 | 681 | 207 | 1 | 1 | Dick Phillips | Recreation Park | Lost in Finals |
| 1981 | MIN | Wisconsin Rapids Twins | Midw | A | team page | 133 | 68 | 65 | 16.5 | 696 | 628 | 68 | 3 | 4 | Ken Staples | Witter Field | dnq |
| 1981 | MIN | Elizabethton Twins | App | Rk | team page | 70 | 42 | 28 | 4.0 | 402 | 331 | 71 | 2 | 2 | Fred Waters | Joe O'Brien Field | dnq |
| 1981 | MON | Montreal Expos | MLB-NL | MLB | team page | 108 | 60 | 48 | -- | 443 | 394 | 49 | 0 | 4 | Dick Williams, Jim Fanning | Olympic Stadium | Lost NLCS (Dodgers) |
| 1981 | MON | Denver Bears | Amer | AAA | team page | 136 | 76 | 60 | 3.0 | 733 | 744 | -11 | 2 | 2 | Felipe Alou | Mile High Stadium | League Champions |
| 1981 | MON | Memphis Chicks | Sou | AA | team page | 143 | 77 | 66 | 4.0 | 746 | 714 | 32 | 2 | 3 | Larry Bearnarth | Tim McCarver Stadium | Lost in Semi-Finals |
| 1981 | MON | West Palm Beach Expos | FSL | A+ | team page | 136 | 65 | 71 | 17.0 | 549 | 614 | -65 | 3 | 7 | Bob Bailey | West Palm Beach Municipal Stadium | dnq |
| 1981 | MON | Jamestown Expos | NYPL | A- | team page | 74 | 48 | 26 | -- | 418 | 333 | 85 | 1 | 2 | Pat Daugherty | College Stadium | Lost in Finals |
| 1981 | MON | Calgary Expos | Pio | Rk | team page | 70 | 46 | 24 | -- | 413 | 358 | 55 | 1 | 1 | J.R. Miner | Burns Stadium | Lost in Finals |
| 1981 | NYN | New York Mets | MLB-NL | MLB | team page | 103 | 41 | 62 | -- | 348 | 432 | -84 | 0 | 10 | Joe Torre | Shea Stadium | dnq |
| 1981 | NYN | Tidewater Tides | IL | AAA | team page | 138 | 70 | 68 | 17.5 | 520 | 558 | -38 | 3 | 3 | Jack Aker | Met Park | Lost in Semi-Finals |
| 1981 | NYN | Jackson Mets | Tex | AA | team page | 68 | 29 | 39 | -- | 532 | 528 | 4 | 0 | 6 | Davey Johnson | Smith-Wills Stadium | League Champions |
| 1981 | NYN | Lynchburg Mets | Caro | A+ | team page | 140 | 71 | 69 | -- | 704 | 680 | 24 | 1 | 6 | Gene Dusan | Lynchburg City Stadium | dnq |
| 1981 | NYN | Shelby Mets | SAL | A | team page | 142 | 59 | 83 | 39.5 | 634 | 763 | -129 | 5 | 9 | Dan Monzon | Veterans Field | dnq |
| 1981 | NYN | Little Falls Mets | NYPL | A- | team page | 70 | 31 | 39 | 15.5 | 355 | 420 | -65 | 3 | 6 | Richard Miller | Little Falls Veterans Memorial Park | dnq |
| 1981 | NYN | Kingsport Mets | App | Rk | team page | 70 | 21 | 49 | 25.0 | 318 | 431 | -113 | 6 | 6 | Al Jackson | Dobyns-Bennett | dnq |
| 1981 | NYA | New York Yankees | MLB-AL | MLB | team page | 107 | 59 | 48 | -- | 421 | 343 | 78 | 0 | 4 | Gene Michael, Bob Lemon | Yankee Stadium I | Lost World Series (Dodgers) |
| 1981 | NYA | Columbus Clippers | IL | AAA | team page | 139 | 88 | 51 | -- | 738 | 604 | 134 | 1 | 1 | Frank Verdi | Cooper Stadium | League Champions |
| 1981 | NYA | Nashville Sounds | Sou | AA | team page | 143 | 81 | 62 | -- | 744 | 574 | 170 | 1 | 1 | Stump Merrill | Herschel Greer Stadium | Lost in Finals |
| 1981 | NYA | Fort Lauderdale Yankees | FSL | A+ | team page | 134 | 81 | 53 | -- | 579 | 421 | 158 | 1 | 1 | Doug Holmquist | Fort Lauderdale Stadium | Lost in Semi-Finals |
| 1981 | NYA | Greensboro Hornets | SAL | A | team page | 141 | 98 | 43 | -- | 788 | 550 | 238 | 1 | 1 | Bob Schaefer | World War Memorial Stadium | League Champions |
| 1981 | NYA | Oneonta Yankees | NYPL | A- | team page | 73 | 48 | 25 | -- | 409 | 326 | 83 | 1 | 1 | Art Mazmanian | Damaschke Field | League Champions |
| 1981 | NYA | Gulf Coast Yankees | GCL | Rk | team page | 59 | 30 | 29 | 11.5 | 260 | 254 | 6 | 7 | 7 | Carlos Tosca | Yankee Complex | dnq |
| 1981 | NYA | Paintsville Yankees | App | Rk | team page | 70 | 46 | 24 | -- | 426 | 317 | 109 | 1 | 1 | Mike Easom | Paul G. Fyffe Field | dnq |
| 1981 | OAK | Oakland Athletics | MLB-AL | MLB | team page | 109 | 64 | 45 | -- | 458 | 403 | 55 | 0 | 1 | Billy Martin | Oakland-Alameda County Coliseum | Lost ALCS (Yankees) |
| 1981 | OAK | Tacoma Tigers | PCL | AAA | team page | 139 | 78 | 61 | -- | 706 | 584 | 122 | 1 | 2 | Edward Nottle | Cheney Stadium | Lost in Finals |
| 1981 | OAK | West Haven A's | East | AA | team page | 138 | 71 | 67 | 8.5 | 588 | 603 | -15 | 3 | 4 | Bob Didier | Quigley Stadium | dnq |
| 1981 | OAK | Modesto A's | Calif | A+ | team page | 138 | 67 | 71 | 19.0 | 671 | 873 | -202 | 5 | 5 | Keith Lieppman | Del Webb Field | dnq |
| 1981 | OAK | Medford A's | Nwst | A- | team page | 70 | 42 | 28 | -- | 404 | 338 | 66 | 1 | 1 | Bradley Fischer | Miles Field | League Champions |
| 1981 | PHI | Philadelphia Phillies | MLB-NL | MLB | team page | 107 | 59 | 48 | -- | 491 | 472 | 19 | 0 | 6 | Dallas Green | Veterans Stadium | Lost in 1st Round (Expos) |
| 1981 | PHI | Oklahoma City 89ers | Amer | AAA | team page | 136 | 69 | 67 | 10.0 | 682 | 647 | 35 | 3 | 4 | Jim Snyder | All Sports Stadium | dnq |
| 1981 | PHI | Reading Phillies | East | AA | team page | 139 | 76 | 63 | 4.0 | 675 | 696 | -21 | 2 | 3 | Ron Clark | Reading Municipal Memorial Stadium | Lost in Semi-Finals |
| 1981 | PHI | Peninsula Pilots | Caro | A+ | team page | 136 | 71 | 65 | 2.0 | 608 | 538 | 70 | 3 | 1 | Bill Dancy | War Memorial Stadium | Lost in Finals |
| 1981 | PHI | Spartanburg Phillies | SAL | A | team page | 141 | 71 | 70 | 27.0 | 641 | 633 | 8 | 3 | 5 | Tom Harmon | Duncan Park | dnq |
| 1981 | PHI | Bend Phillies | Nwst | A- | team page | 170 | 31 | 139 | 58.0 | 371 | 421 | -50 | 2 | 6 | P.J. Carey | Vince Genna Stadium | dnq |
| 1981 | PHI | Helena Phillies | Pio | Rk | team page | 70 | 26 | 44 | 13.0 | 363 | 463 | -100 | 4 | 8 | Roly De Armas | Kindrick Field | dnq |
| 1981 | PIT | Pittsburgh Pirates | MLB-NL | MLB | team page | 102 | 46 | 56 | -- | 407 | 425 | -18 | 0 | 9 | Chuck Tanner | Three Rivers Stadium | dnq |
| 1981 | PIT | Portland Beavers | PCL | AAA | team page | 137 | 72 | 65 | 5.0 | 654 | 631 | 23 | 3 | 3 | Pete Ward | Civic Stadium | dnq |
| 1981 | PIT | Buffalo Bisons | East | AA | team page | 137 | 56 | 81 | 28.0 | 616 | 709 | -93 | 4 | 7 | Johnny Lipon | War Memorial Stadium | dnq |
| 1981 | PIT | Alexandria Dukes | Caro | A+ | team page | 137 | 62 | 75 | 7.5 | 632 | 648 | -16 | 4 | 8 | Michael Toomey | Municipal Stadium | dnq |
| 1981 | PIT | Greenwood Pirates | SAL | A | team page | 144 | 79 | 65 | -- | 681 | 705 | -24 | 1 | 2 | Joe Frisina | Legion Stadium | Lost in Finals |
| 1981 | PIT | Gulf Coast Pirates | GCL | Rk | team page | 60 | 32 | 28 | 10.0 | 259 | 284 | -25 | 5 | 5 | Woody Huyke | Pirate City Stadium | dnq |
| 1981 | SDN | San Diego Padres | MLB-NL | MLB | team page | 110 | 41 | 69 | -- | 382 | 455 | -73 | 0 | 11 | Frank Howard | Jack Murphy Stadium | dnq |
| 1981 | SDN | Hawaii Islanders | PCL | AAA | team page | 137 | 72 | 65 | 5.0 | 627 | 617 | 10 | 2 | 4 | Doug Rader | Aloha Stadium | Lost in Semi-Finals |
| 1981 | SDN | Amarillo Gold Sox | Tex | AA | team page | 68 | 42 | 26 | -- | 667 | 574 | 93 | 0 | 1 | Eddie Watt | Potter County Memorial Stadium | Lost in Semi-Finals |
| 1981 | SDN | Reno Silver Sox | Calif | A+ | team page | 139 | 81 | 58 | 5.5 | 986 | 838 | 148 | 2 | 2 | Jack Maloof | Moana Stadium | Lost in Semi-Finals |
| 1981 | SDN | Salem Redbirds | Caro | A+ | team page | 140 | 66 | 74 | 5.0 | 699 | 794 | -95 | 3 | 7 | Glenn Ezell | Salem Municipal Stadium | Lost in Semi-Finals |
| 1981 | SDN | Walla Walla Padres | Nwst | A- | team page | 70 | 29 | 41 | 10.0 | 377 | 438 | -61 | 3 | 5 | Greg Riddoch | Borleske Stadium | dnq |
| 1981 | SDN | Gulf Coast Padres | GCL | Rk | team page | 63 | 25 | 38 | 18.5 | 235 | 268 | -33 | 11 | 10 | Jim Zerilla | McKechnie Field | dnq |
| 1981 | SFN | San Francisco Giants | MLB-NL | MLB | team page | 111 | 56 | 55 | -- | 427 | 414 | 13 | 0 | 7 | Frank Robinson | Candlestick Park | dnq |
| 1981 | SFN | Phoenix Giants | PCL | AAA | team page | 132 | 69 | 63 | 25.0 | 686 | 710 | -24 | 2 | 5 | Rocky Bridges | Phoenix Municipal Stadium | dnq |
| 1981 | SFN | Shreveport Captains | Tex | AA | team page | 69 | 32 | 37 | -- | 547 | 563 | -16 | 0 | 5 | Jack Mull | SPAR Stadium | dnq |
| 1981 | SFN | Fresno Giants | Calif | A+ | team page | 140 | 63 | 77 | 24.0 | 687 | 26 | 661 | 7 | 7 | Wayne Cato | Euless Ballpark | dnq |
| 1981 | SFN | Clinton Giants | Midw | A | team page | 132 | 52 | 80 | 23.5 | 537 | 617 | -80 | 4 | 8 | Wendell Kim | Riverview Stadium | dnq |
| 1981 | SFN | Great Falls Giants | Pio | Rk | team page | 70 | 32 | 38 | 14.0 | 379 | 339 | 40 | 4 | 5 | Ernie Rodriguez | Legion Field | dnq |
| 1981 | SEA | Seattle Mariners | MLB-AL | MLB | team page | 109 | 44 | 65 | -- | 426 | 521 | -95 | 0 | 12 | Rene Lachemann, Maury Wills | The Kingdome | dnq |
| 1981 | SEA | Spokane Indians | PCL | AAA | team page | 140 | 56 | 84 | 22.5 | 627 | 705 | -78 | 5 | 10 | Rene Lachemann, Ken Pape | Avista Stadium | dnq |
| 1981 | SEA | Lynn Sailors | East | AA | team page | 138 | 62 | 76 | 22.5 | 530 | 562 | -32 | 3 | 6 | Bobby Floyd | Fraser Field | dnq |
| 1981 | SEA | Wausau Timbers | Midw | A | team page | 132 | 84 | 48 | -- | 767 | 552 | 215 | 1 | 1 | Bill Plummer | Athletic Park | League Champions |
| 1981 | SEA | Bellingham Mariners | Nwst | A- | team page | 70 | 39 | 31 | -- | 364 | 353 | 11 | 1 | 2 | Jeff Scott | Joe Martin Field | Lost in Finals |
| 1981 | SLN | St. Louis Cardinals | MLB-NL | MLB | team page | 102 | 59 | 43 | -- | 464 | 417 | 47 | 0 | 2 | Whitey Herzog | Busch Stadium II | dnq |
| 1981 | SLN | Springfield Redbirds | Amer | AAA | team page | 136 | 66 | 70 | 7.0 | 659 | 602 | 57 | 2 | 5 | Tommy Thompson | Lanphier Park | dnq |
| 1981 | SLN | Arkansas Travelers | Tex | AA | team page | 68 | 27 | 41 | -- | 504 | 606 | -102 | 0 | 8 | Gaylen Pitts | Ray Winder Field | dnq |
| 1981 | SLN | St. Petersburg Cardinals | FSL | A+ | team page | 132 | 69 | 63 | 9.5 | 554 | 537 | 17 | 3 | 4 | Nick Leyva | Al Lang Field | dnq |
| 1981 | SLN | Gastonia Cardinals | SAL | A | team page | 144 | 68 | 76 | 31.5 | 541 | 557 | -16 | 4 | 7 | Joseph Rigoli | Sims Legion Park | dnq |
| 1981 | SLN | Erie Cardinals | NYPL | A- | team page | 74 | 44 | 30 | 4.0 | 467 | 363 | 104 | 2 | 3 | Sonny Roberts | Ainsworth Field | dnq |
| 1981 | SLN | Johnson City Cardinals | App | Rk | team page | 70 | 36 | 34 | 10.0 | 341 | 321 | 20 | 4 | 3 | Johnny Lewis | Howard Johnson Field | dnq |
| 1981 | TEX | Texas Rangers | MLB-AL | MLB | team page | 105 | 57 | 48 | -- | 452 | 389 | 63 | 0 | 7 | Don Zimmer | Arlington Stadium | dnq |
| 1981 | TEX | Wichita Aeros | Amer | AAA | team page | 135 | 65 | 70 | 13.5 | 615 | 718 | -103 | 4 | 6 | Rich Donnelly | Lawrence-Dumont Stadium | dnq |
| 1981 | TEX | Tulsa Drillers | Tex | AA | team page | 66 | 36 | 30 | -- | 592 | 544 | 48 | 0 | 3 | Tom Burgess | Robert B. Sutton | Lost in Semi-Finals |
| 1981 | TEX | Asheville Tourists | SAL | A | team page | 142 | 74 | 68 | 24.5 | 774 | 676 | 98 | 2 | 4 | Tom Robson | McCormick Field | dnq |
| 1981 | TEX | Gulf Coast Rangers | GCL | Rk | team page | 62 | 32 | 30 | 11.0 | 263 | 227 | 36 | 6 | 6 | Andy Hancock | Payne Park | dnq |
| 1981 | TOR | Toronto Blue Jays | MLB-AL | MLB | team page | 106 | 37 | 69 | -- | 329 | 466 | -137 | 0 | 14 | Bobby Mattick | Exhibition Stadium | dnq |
| 1981 | TOR | Syracuse Chiefs | IL | AAA | team page | 140 | 60 | 80 | 28.5 | 616 | 673 | -57 | 7 | 7 | Bob Humphreys | MacArthur Stadium | dnq |
| 1981 | TOR | Knoxville Blue Jays | Sou | AA | team page | 143 | 63 | 80 | 18.0 | 600 | 708 | -108 | 5 | 10 | Larry Hardy, Duane Larson | Bill Meyer Stadium | dnq |
| 1981 | TOR | Kinston Eagles | Caro | A+ | team page | 140 | 72 | 68 | -- | 588 | 635 | -47 | 1 | 3 | John McLaren | Grainger Stadium | Lost in Semi-Finals |
| 1981 | TOR | Florence Blue Jays | SAL | A | team page | 138 | 66 | 72 | 10.0 | 628 | 638 | -10 | 3 | 6 | Dennis Holmberg | Red Wolfe Stadium | dnq |
| 1981 | TOR | Gulf Coast Blue Jays | GCL | Rk | team page | 65 | 26 | 39 | 18.5 | 247 | 312 | -65 | 9 | 9 | Rich Hacker | Bobby Mattick Training Center | dnq |
| 1981 | TOR | Medicine Hat Blue Jays | Pio | Rk | team page | 70 | 37 | 33 | 9.0 | 388 | 402 | -14 | 3 | 4 | Wayne Graham | Athletic Park | dnq |