| 2000-01-06 | Terry Jones | New York Yankees | Traded by Los Angeles Dodgers to New York Yankees for future considerations | MLB |
| 2000-01-07 | Ken Ray | San Francisco Giants | Traded from Kansas City Royals to San Francisco Giants for Jerry Spradlin (12/13/1999) | MLB |
| 2000-01-12 | Cal Eldred | Chicago White Sox | Traded from Milwaukee Brewers with Jose Valentin to Chicago White Sox for Jaime Navarro and John Snyder | MLB |
| 2000-01-12 | Jose Valentin | Chicago White Sox | Traded from Milwaukee Brewers with Cal Eldred to Chicago White Sox for Jaime Navarro and John Snyder | MLB |
| 2000-01-12 | Jaime Navarro | Milwaukee Brewers | Traded from Chicago White Sox with John Snyder to Milwaukee Brewers for Cal Eldred and Jose Valentin | MLB |
| 2000-01-12 | John Snyder | Milwaukee Brewers | Traded from Chicago White Sox with Jaime Navarro to Milwaukee Brewers for Cal Eldred and Jose Valentin | MLB |
| 2000-01-14 | Alex Ochoa | Cincinnati Reds | Traded from Milwaukee Brewers to Cincinnati Reds for Mark Sweeney and Gene Altman (5/15/2000) | MLB |
| 2000-01-14 | Mark Sweeney | Milwaukee Brewers | Traded from Cincinnati Reds with Gene Altman to Milwaukee Brewers for Alex Ochoa | MLB |
| 2000-01-14 | Masato Yoshii | Colorado Rockies | Traded from New York Mets to Colorado Rockies for Lariel Gonzalez and Bobby Jones | MLB |
| 2000-01-14 | Lariel Gonzalez | New York Mets | Traded from Colorado Rockies with Bobby Jones to New York Mets for Masato Yoshii | MLB |
| 2000-01-14 | Bobby Jones | New York Mets | Traded from Colorado Rockies with Lariel Gonzalez to New York Mets for Masato Yoshii | MLB |
| 2000-01-21 | Luis Lopez | Milwaukee Brewers | Traded from New York Mets to Milwaukee Brewers for Bill Pulsipher | MLB |
| 2000-01-21 | Bill Pulsipher | New York Mets | Traded from Milwaukee Brewers to New York Mets for Luis Lopez | MLB |
| 2000-02-10 | Ken Griffey | Cincinnati Reds | Traded from Seattle Mariners to Cincinnati Reds for Mike Cameron, Brett Tomko, Jake Meyer and Antonio Perez | MLB |
| 2000-02-10 | Mike Cameron | Seattle Mariners | Traded from Cincinnati Reds with Brett Tomko, Jake Meyer and Antonio Perez to Seattle Mariners for Ken Griffey | MLB |
| 2000-02-10 | Brett Tomko | Seattle Mariners | Traded from Cincinnati Reds with Mike Cameron, Jake Meyer and Antonio Perez to Seattle Mariners for Ken Griffey | MLB |
| 2000-02-10 | Antonio Perez | Seattle Mariners | Traded from Cincinnati Reds with Mike Cameron, Brett Tomko and Jake Meyer to Seattle Mariners for Ken Griffey | MLB |
| 2000-02-18 | Brett Laxton | Kansas City Royals | Traded from Oakland Athletics to Kansas City Royals for Jeremy Giambi | MLB |
| 2000-02-18 | Jeremy Giambi | Oakland Athletics | Traded from Kansas City Royals to Oakland Athletics for Brett Laxton | MLB |
| 2000-02-23 | John Vander Wal | Pittsburgh Pirates | Traded from San Diego Padres with Geraldo Padua and Jim Sak to Pittsburgh Pirates for Al Martin | MLB |
| 2000-02-23 | Al Martin | San Diego Padres | Traded from Pittsburgh Pirates to San Diego Padres for John Vander Wal, Geraldo Padua and Jim Sak | MLB |
| 2000-03-07 | Gregg Zaun | Kansas City Royals | Traded by Detroit Tigers to Kansas City Royals for future considerations | MLB |
| 2000-03-10 | Wendell Magee | Detroit Tigers | Traded from Philadelphia Phillies to Detroit Tigers for Bobby Sismondo | MLB |
| 2000-03-13 | Freddy Garcia | Cincinnati Reds | Traded from Atlanta Braves to Cincinnati Reds for Dennis Russo | MLB |
| 2000-03-16 | Lee Stevens | Montreal Expos | Traded from Texas Rangers to Montreal Expos for David Segui | MLB |
| 2000-03-16 | David Segui | Texas Rangers | Traded from Toronto Blue Jays to Texas Rangers for Brad Fullmer | MLB |
| 2000-03-16 | Brad Fullmer | Toronto Blue Jays | Traded from Montreal Expos to Toronto Blue Jays for Lee Stevens | MLB |
| 2000-03-17 | Ted Lilly | New York Yankees | Traded from Montreal Expos with Jake Westbrook and Christian Parker to New York Yankees for Hideki Irabu (12/22/1999) | MLB |
| 2000-03-18 | Joe McEwing | New York Mets | Traded from St. Louis Cardinals to New York Mets for Jesse Orosco | MLB |
| 2000-03-18 | Jesse Orosco | St. Louis Cardinals | Traded from New York Mets to St. Louis Cardinals for Joe McEwing | MLB |
| 2000-03-21 | Carlos Maldonado | Houston Astros | Traded from Mariners to Astros for Carlos Hernandez | MLB |
| 2000-03-21 | Carlos Hernandez | Seattle Mariners | Traded from Houston Astros to Seattle Mariners for Carlos Maldonado | MLB |
| 2000-03-22 | Christian Parker | New York Yankees | Traded from Montreal Expos with Jake Westbrook and Ted Lilly to New York Yankees for Hideki Irabu (12/22/1999) | MLB |
| 2000-03-23 | Jim Mann | New York Mets | Traded from Toronto Blue Jays to New York Mets for Jerson Perez | MLB |
| 2000-03-23 | Kent Bottenfield | Anaheim Angels | Traded from St. Louis Cardinals with Adam Kennedy to Anaheim Angels for Jim Edmonds | MLB |
| 2000-03-23 | Adam Kennedy | Anaheim Angels | Traded from St. Louis Cardinals with Kent Bottenfield to Anaheim Angels for Jim Edmonds | MLB |
| 2000-03-23 | Jim Edmonds | St. Louis Cardinals | Traded from Anaheim Angels to St. Louis Cardinals for Kent Bottenfield and Adam Kennedy | MLB |
| 2000-03-23 | Gary Matthews | Chicago Cubs | Traded from San Diego Padres to Chicago Cubs for Rodney Myers | MLB |
| 2000-03-23 | Rodney Myers | San Diego Padres | Traded from Chicago Cubs to San Diego Padres for Gary Matthews | MLB |
| 2000-03-23 | Wilson Delgado | New York Yankees | Traded from San Francisco Giants to New York Yankees for Juan Melo | MLB |
| 2000-03-23 | Juan Melo | San Francisco Giants | Traded from New York Yankees to San Francisco Giants for Wilson Delgado | MLB |
| 2000-03-27 | Steve Falteisek | Florida Marlins | Traded from Cleveland Indians to Florida Marlins for Victor Rodriguez | MLB |
| 2000-03-29 | Edgard Clemente | Anaheim Angels | Traded from Colorado Rockies to Anaheim Angels for Jason Dewey and Norm Hutchins | MLB |
| 2000-03-29 | Yorkis Perez | Houston Astros | Traded from Philadelphia Phillies to Houston Astros for Trever Miller | MLB |
| 2000-03-29 | Trever Miller | Philadelphia Phillies | Traded from Houston Astros to Philadelphia Phillies for Yorkis Perez | MLB |
| 2000-03-31 | Carlos Mendoza | Colorado Rockies | Traded by New York Mets to Colorado Rockies for future considerations | MLB |
| 2000-04-01 | Juan Castro | Cincinnati Reds | Traded from Los Angeles Dodgers to Cincinnati Reds for Kenny Lutz | MLB |
| 2000-04-07 | Manny Aybar | Cincinnati Reds | Traded from Colorado Rockies to Cincinnati Reds for Gabe White | MLB |
| 2000-04-07 | Gabe White | Colorado Rockies | Traded from Cincinnati Reds to Colorado Rockies for Manny Aybar | MLB |
| 2000-04-14 | Ray King | Milwaukee Brewers | Traded from Chicago Cubs to Milwaukee Brewers for Doug Johns | MLB |
| 2000-04-20 | Brian Dallimore | Arizona Diamondbacks | Traded from Houston Astros to Arizona Diamondbacks for Josh McAffee | MLB |
| 2000-04-25 | Brad Rigby | Montreal Expos | Traded from Kansas City Royals to Montreal Expos for Miguel Batista | MLB |
| 2000-04-25 | Miguel Batista | Kansas City Royals | Traded from Montreal Expos to Kansas City Royals for Brad Rigby | MLB |
| 2000-04-26 | Curtis Pride | Boston Red Sox | Traded by New York Mets to Boston Red Sox for future considerations | MLB |
| 2000-05-01 | Simon Pond | Cleveland Indians | Traded by Montreal Expos to Cleveland Indians for future considerations | MLB |
| 2000-05-12 | Dave Martinez | Chicago Cubs | Traded from Tampa Bay Devil Rays to Chicago Cubs for Mark Guthrie | MLB |
| 2000-05-12 | Mark Guthrie | Tampa Bay Devil Rays | Traded from Chicago Cubs to Tampa Bay Devil Rays for Dave Martinez | MLB |
| 2000-05-27 | Marc Valdes | Houston Astros | Traded from Tampa Bay Devil Rays to Houston Astros for Russ Johnson | MLB |
| 2000-05-27 | Russ Johnson | Tampa Bay Devil Rays | Traded from Houston Astros to Tampa Bay Devil Rays for Marc Valdes | MLB |
| 2000-05-31 | Tony Graffanino | Chicago White Sox | Traded from Tampa Bay Devil Rays to Chicago White Sox for Tanyon Sturtze | MLB |
| 2000-05-31 | Tanyon Sturtze | Tampa Bay Devil Rays | Traded from Chicago White Sox to Tampa Bay Devil Rays for Tony Graffanino | MLB |
| 2000-06-02 | Bill Pulsipher | Arizona Diamondbacks | Traded from New York Mets to Arizona Diamondbacks for Lenny Harris | MLB |
| 2000-06-02 | Lenny Harris | New York Mets | Traded from Arizona Diamondbacks to New York Mets for Bill Pulsipher | MLB |
| 2000-06-09 | Brant Brown | Texas Rangers | Traded from Florida Marlins to Texas Rangers for Chuck Smith | MLB |
| 2000-06-09 | Chuck Smith | Florida Marlins | Traded from Texas Rangers to Florida Marlins for Brant Brown | MLB |
| 2000-06-09 | Dave Martinez | Texas Rangers | Traded from Chicago Cubs to Texas Rangers for Brant Brown | MLB |
| 2000-06-09 | Danny Bautista | Arizona Diamondbacks | Traded from Florida Marlins to Arizona Diamondbacks for Andy Fox | MLB |
| 2000-06-09 | Andy Fox | Florida Marlins | Traded from Arizona Diamondbacks to Florida Marlins for Danny Bautista | MLB |
| 2000-06-10 | Brant Brown | Chicago Cubs | Traded from Texas Rangers to Chicago Cubs for Dave Martinez | MLB |
| 2000-06-12 | Karim Garcia | Baltimore Orioles | Traded by Detroit Tigers to Baltimore Orioles for future considerations | MLB |
| 2000-06-12 | Mike Romano | Minnesota Twins | Traded from Toronto Blue Jays to Minnesota Twins for Francisco Alvarez | MLB |
| 2000-06-13 | Eliezer Alfonzo | Milwaukee Brewers | Traded from St. Louis Cardinals with Juan Acevedo and Matt Parker to Milwaukee Brewers for Fernando Vina (12/20/1999) | MLB |
| 2000-06-13 | Al Reyes | Los Angeles Dodgers | Traded from Baltimore Orioles to Los Angeles Dodgers for Alan Mills | MLB |
| 2000-06-13 | Alan Mills | Baltimore Orioles | Traded from Los Angeles Dodgers to Baltimore Orioles for Al Reyes | MLB |
| 2000-06-17 | Adam Melhuse | Colorado Rockies | Traded by Los Angeles Dodgers to Colorado Rockies for future considerations | MLB |
| 2000-06-20 | Jim Leyritz | Los Angeles Dodgers | Traded from New York Yankees to Los Angeles Dodgers for Jose Vizcaino | MLB |
| 2000-06-20 | Jose Vizcaino | New York Yankees | Traded from Los Angeles Dodgers to New York Yankees for Jim Leyritz | MLB |
| 2000-06-28 | Darren Holmes | Baltimore Orioles | Traded by St. Louis Cardinals to Baltimore Orioles for future considerations | MLB |
| 2000-06-28 | Ed Vosberg | Philadelphia Phillies | Traded by Colorado Rockies to Philadelphia Phillies for future considerations | MLB |
| 2000-06-28 | Dan Serafini | Pittsburgh Pirates | Traded from San Diego Padres to Pittsburgh Pirates for Andy Bausher (8/8/2000) | MLB |
| 2000-06-29 | Ricky Ledee | Cleveland Indians | Traded from New York Yankees with Jake Westbrook and Zach Day to Cleveland Indians for David Justice | MLB |
| 2000-06-29 | Jake Westbrook | Cleveland Indians | Traded from New York Yankees with Ricky Ledee and Zach Day to Cleveland Indians for David Justice | MLB |
| 2000-06-29 | Zach Day | Cleveland Indians | Traded from New York Yankees with Ricky Ledee and Jake Westbrook to Cleveland Indians for David Justice | MLB |
| 2000-06-29 | David Justice | New York Yankees | Traded from Cleveland Indians to New York Yankees for Ricky Ledee, Jake Westbrook and Zach Day | MLB |
| 2000-06-30 | Ed Sprague | Boston Red Sox | Traded from San Diego Padres to Boston Red Sox for Cesar Saba and Dennis Tankersley | MLB |
| 2000-06-30 | Dennis Tankersley | San Diego Padres | Traded from Boston Red Sox with Cesar Saba to San Diego Padres for Ed Sprague | MLB |
| 2000-07-12 | Ed Yarnall | Cincinnati Reds | Traded from New York Yankees with Drew Henson, Jackson Melian and Brian Reith to Cincinnati Reds for Mike Frank and Denny Neagle | MLB |
| 2000-07-12 | Drew Henson | Cincinnati Reds | Traded from New York Yankees with Ed Yarnall, Jackson Melian and Brian Reith to Cincinnati Reds for Mike Frank and Denny Neagle | MLB |
| 2000-07-12 | Brian Reith | Cincinnati Reds | Traded from New York Yankees with Ed Yarnall, Drew Henson and Jackson Melian to Cincinnati Reds for Mike Frank and Denny Neagle | MLB |
| 2000-07-12 | Mike Frank | New York Yankees | Traded from Cincinnati Reds with Denny Neagle to New York Yankees for Ed Yarnall, Drew Henson, Jackson Melian and Brian Reith | MLB |
| 2000-07-12 | Denny Neagle | New York Yankees | Traded from Cincinnati Reds with Mike Frank to New York Yankees for Ed Yarnall, Drew Henson, Jackson Melian and Brian Reith | MLB |
| 2000-07-12 | Bruce Chen | Philadelphia Phillies | Traded from Atlanta Braves with Jimmy Osting to Philadelphia Phillies for Andy Ashby | MLB |
| 2000-07-12 | Jimmy Osting | Philadelphia Phillies | Traded from Atlanta Braves with Bruce Chen to Philadelphia Phillies for Andy Ashby | MLB |
| 2000-07-12 | Andy Ashby | Atlanta Braves | Traded from Philadelphia Phillies to Atlanta Braves for Bruce Chen and Jimmy Osting | MLB |
| 2000-07-15 | Butch Huskey | Colorado Rockies | Traded from Minnesota Twins with Todd Walker to Colorado Rockies for Todd Sears | MLB |
| 2000-07-15 | Todd Walker | Colorado Rockies | Traded from Minnesota Twins with Butch Huskey to Colorado Rockies for Todd Sears | MLB |
| 2000-07-15 | Todd Sears | Minnesota Twins | Traded from Colorado Rockies to Minnesota Twins for Butch Huskey and Todd Walker | MLB |
| 2000-07-17 | Gabe Alvarez | San Diego Padres | Traded from Detroit Tigers to San Diego Padres for Dusty Allen | MLB |
| 2000-07-17 | Dusty Allen | Detroit Tigers | Traded from San Diego Padres to Detroit Tigers for Gabe Alvarez | MLB |
| 2000-07-19 | Darwin Cubillan | Texas Rangers | Traded from Toronto Blue Jays with Michael Young to Texas Rangers for Esteban Loaiza | MLB |
| 2000-07-19 | Michael Young | Texas Rangers | Traded from Toronto Blue Jays with Darwin Cubillan to Texas Rangers for Esteban Loaiza | MLB |
| 2000-07-19 | Esteban Loaiza | Toronto Blue Jays | Traded from Texas Rangers to Toronto Blue Jays for Darwin Cubillan and Michael Young | MLB |
| 2000-07-21 | Ben Ford | Chicago Cubs | Traded from New York Yankees with Oswaldo Mairena to Chicago Cubs for Glenallen Hill | MLB |
| 2000-07-21 | Oswaldo Mairena | Chicago Cubs | Traded from New York Yankees with Ben Ford to Chicago Cubs for Glenallen Hill | MLB |
| 2000-07-21 | Glenallen Hill | New York Yankees | Traded from Chicago Cubs to New York Yankees for Ben Ford and Oswaldo Mairena | MLB |
| 2000-07-25 | Kevin Brown | Milwaukee Brewers | Traded from Toronto Blue Jays to Milwaukee Brewers for Alvin Morrow | MLB |
| 2000-07-26 | Eric Gunderson | San Francisco Giants | Traded by Toronto Blue Jays to San Francisco Giants for future considerations | MLB |
| 2000-07-26 | Curt Schilling | Arizona Diamondbacks | Traded from Philadelphia Phillies to Arizona Diamondbacks for Omar Daal, Nelson Figueroa, Travis Lee and Vicente Padilla | MLB |
| 2000-07-26 | Omar Daal | Philadelphia Phillies | Traded from Arizona Diamondbacks with Nelson Figueroa, Travis Lee and Vicente Padilla to Philadelphia Phillies for Curt Schilling | MLB |
| 2000-07-26 | Nelson Figueroa | Philadelphia Phillies | Traded from Arizona Diamondbacks with Omar Daal, Travis Lee and Vicente Padilla to Philadelphia Phillies for Curt Schilling | MLB |
| 2000-07-26 | Travis Lee | Philadelphia Phillies | Traded from Arizona Diamondbacks with Omar Daal, Nelson Figueroa and Vicente Padilla to Philadelphia Phillies for Curt Schilling | MLB |
| 2000-07-26 | Vicente Padilla | Philadelphia Phillies | Traded from Arizona Diamondbacks with Omar Daal, Nelson Figueroa and Travis Lee to Philadelphia Phillies for Curt Schilling | MLB |
| 2000-07-26 | Manny Aybar | Florida Marlins | Traded from Cincinnati Reds to Florida Marlins for Jorge Cordova | MLB |
| 2000-07-26 | Jamie Arnold | Chicago Cubs | Traded from Los Angeles Dodgers with Jorge Piedra to Chicago Cubs for Ismael Valdez | MLB |
| 2000-07-26 | Jorge Piedra | Chicago Cubs | Traded from Los Angeles Dodgers with Jamie Arnold to Chicago Cubs for Ismael Valdez | MLB |
| 2000-07-26 | Ismael Valdez | Los Angeles Dodgers | Traded from Chicago Cubs to Los Angeles Dodgers for Jamie Arnold and Jorge Piedra | MLB |
| 2000-07-26 | Rob Ducey | Toronto Blue Jays | Traded from Philadelphia Phillies to Toronto Blue Jays for John Sneed (7/31/2000) | MLB |
| 2000-07-27 | Jeff Frye | Colorado Rockies | Traded from Boston Red Sox with Brian Rose, John Wasdin and Jeff Taglienti to Colorado Rockies for Rolando Arrojo, Rich Croushore and Mike Lansing | MLB |
| 2000-07-27 | Brian Rose | Colorado Rockies | Traded from Boston Red Sox with Jeff Frye, John Wasdin and Jeff Taglienti to Colorado Rockies for Rolando Arrojo, Rich Croushore and Mike Lansing | MLB |
| 2000-07-27 | John Wasdin | Colorado Rockies | Traded from Boston Red Sox with Jeff Frye, Brian Rose and Jeff Taglienti to Colorado Rockies for Rolando Arrojo, Rich Croushore and Mike Lansing | MLB |
| 2000-07-27 | Rolando Arrojo | Boston Red Sox | Traded from Colorado Rockies with Rich Croushore and Mike Lansing to Boston Red Sox for Jeff Frye, Brian Rose, John Wasdin and Jeff Taglienti | MLB |
| 2000-07-27 | Rick Croushore | Boston Red Sox | Traded from Colorado Rockies with Rolando Arrojo and Mike Lansing to Boston Red Sox for Jeff Frye, Brian Rose, John Wasdin and Jeff Taglienti | MLB |
| 2000-07-27 | Mike Lansing | Boston Red Sox | Traded from Colorado Rockies with Rolando Arrojo and Rich Croushore to Boston Red Sox for Jeff Frye, Brian Rose, John Wasdin and Jeff Taglienti | MLB |
| 2000-07-28 | Brett Hinchliffe | Chicago Cubs | Traded from Anaheim Angels with Keith Luuloa to Chicago Cubs for Chris Hatcher, Mike Heathcott and Brett King | MLB |
| 2000-07-28 | Keith Luuloa | Chicago Cubs | Traded from Anaheim Angels with Brett Hinchcliffe to Chicago Cubs for Chris Hatcher, Mike Heathcott and Brett King | MLB |
| 2000-07-28 | Chris Hatcher | Anaheim Angels | Traded from Chicago Cubs with Mike Heathcott and Brett King to Anaheim Angels for Brett Hinchcliffe and Keith Luuloa | MLB |
| 2000-07-28 | Mike Heathcott | Anaheim Angels | Traded from Chicago Cubs with Chris Hatcher and Brett King to Anaheim Angels for Brett Hinchcliffe and Keith Luuloa | MLB |
| 2000-07-28 | Paul Rigdon | Milwaukee Brewers | Traded from Cleveland Indians with Richie Sexson, Kane Davis and Marco Scutaro to Milwaukee Brewers for Bob Wickman, Steve Woodard and Jason Bere | MLB |
| 2000-07-28 | Richie Sexson | Milwaukee Brewers | Traded from Cleveland Indians with Paul Rigdon, Kane Davis and Marco Scutaro to Milwaukee Brewers for Bob Wickman, Steve Woodard and Jason Bere | MLB |
| 2000-07-28 | Kane Davis | Milwaukee Brewers | Traded from Cleveland Indians with Paul Rigdon, Richie Sexson and Marco Scutaro to Milwaukee Brewers for Bob Wickman, Steve Woodard and Jason Bere | MLB |
| 2000-07-28 | Bob Wickman | Cleveland Indians | Traded from Milwaukee Brewers with Steve Woodard and Jason Bere to Cleveland Indians for Paul Rigdon, Richie Sexson, Kane Davis and Marco Scutaro (8/30/2000) | MLB |
| 2000-07-28 | Steve Woodard | Cleveland Indians | Traded from Milwaukee Brewers with Bob Wickman and Jason Bere to Cleveland Indians for Paul Rigdon, Richie Sexson, Kane Davis and Marco Scutaro (8/30/2000) | MLB |
| 2000-07-28 | Jason Bere | Cleveland Indians | Traded from Milwaukee Brewers with Bob Wickman and Steve Woodard to Cleveland Indians for Paul Rigdon, Richie Sexson, Kane Davis and Marco Scutaro (8/30/2000) | MLB |
| 2000-07-28 | Alex Ramirez | Pittsburgh Pirates | Traded from Cleveland Indians with Enrique Wilson to Pittsburgh Pirates for Wil Cordero | MLB |
| 2000-07-28 | Enrique Wilson | Pittsburgh Pirates | Traded from Cleveland Indians with Alex Ramirez to Pittsburgh Pirates for Wil Cordero | MLB |
| 2000-07-28 | Wil Cordero | Cleveland Indians | Traded from Pittsburgh Pirates to Cleveland Indians for Alex Ramirez and Enrique Wilson | MLB |
| 2000-07-28 | Todd Belitz | Oakland Athletics | Traded from Tampa Bay Devil Rays with Jim Mecir to Oakland Athletics for Jesus Colome | MLB |
| 2000-07-28 | Jim Mecir | Oakland Athletics | Traded from Tampa Bay Devil Rays with Todd Belitz to Oakland Athletics for Jesus Colome | MLB |
| 2000-07-28 | Jesus Colome | Tampa Bay Devil Rays | Traded from Oakland Athletics to Tampa Bay Devil Rays for Todd Belitz and Jim Mecir | MLB |
| 2000-07-28 | Ricky Ledee | Texas Rangers | Traded from Cleveland Indians to Texas Rangers for David Segui | MLB |
| 2000-07-28 | David Segui | Cleveland Indians | Traded from Texas Rangers to Cleveland Indians for Ricky Ledee | MLB |
| 2000-07-28 | Mike Bordick | New York Mets | Traded from Baltimore Orioles to New York Mets for Leslie Brea, Pat Gorman, Mike Kinkade and Melvin Mora | MLB |
| 2000-07-28 | Lesli Brea | Baltimore Orioles | Traded from New York Mets with Pat Gorman, Mike Kinkade and Melvin Mora to Baltimore Orioles for Mike Bordick | MLB |
| 2000-07-28 | Mike Kinkade | Baltimore Orioles | Traded from New York Mets with Leslie Brea, Pat Gorman and Melvin Mora to Baltimore Orioles for Mike Bordick | MLB |
| 2000-07-28 | Melvin Mora | Baltimore Orioles | Traded from New York Mets with Leslie Brea, Pat Gorman and Mike Kinkade to Baltimore Orioles for Mike Bordick | MLB |
| 2000-07-28 | Bubba Trammell | New York Mets | Traded from Tampa Bay Devil Rays with Rick White to New York Mets for Jason Tyner and Paul Wilson | MLB |
| 2000-07-28 | Rick White | New York Mets | Traded from Tampa Bay Devil Rays with Bubba Trammell to New York Mets for Jason Tyner and Paul Wilson | MLB |
| 2000-07-28 | Jason Tyner | Tampa Bay Devil Rays | Traded from New York Mets with Paul Wilson to Tampa Bay Devil Rays for Bubba Trammell and Rick White | MLB |
| 2000-07-28 | Paul Wilson | Tampa Bay Devil Rays | Traded from New York Mets with Jason Tyner to Tampa Bay Devil Rays for Bubba Trammell and Rick White | MLB |
| 2000-07-29 | Brook Fordyce | Baltimore Orioles | Traded from Chicago White Sox with Miguel Felix, Juan Figueroa and Jason Lakman to Baltimore Orioles for Harold Baines and Charles Johnson | MLB |
| 2000-07-29 | Harold Baines | Chicago White Sox | Traded from Baltimore Orioles with Charles Johnson to Chicago White Sox for Miguel Felix, Juan Figueroa, Brook Fordyce and Jason Lakman | MLB |
| 2000-07-29 | Charles Johnson | Chicago White Sox | Traded from Baltimore Orioles with Harold Baines to Chicago White Sox for Miguel Felix, Juan Figueroa, Brook Fordyce and Jason Lakman | MLB |
| 2000-07-29 | Mike Timlin | St. Louis Cardinals | Traded from Baltimore Orioles to St. Louis Cardinals for Chris Richard and Mark Nussbeck | MLB |
| 2000-07-29 | Chris Richard | Baltimore Orioles | Traded from St. Louis Cardinals with Mark Nussbeck to Baltimore Orioles for Mike Timlin | MLB |
| 2000-07-29 | Kent Bottenfield | Philadelphia Phillies | Traded from Anaheim Angels to Philadelphia Phillies for Ron Gant | MLB |
| 2000-07-29 | Ron Gant | Anaheim Angels | Traded from Philadelphia Phillies to Anaheim Angels for Kent Bottenfield | MLB |
| 2000-07-29 | Jason Christiansen | St. Louis Cardinals | Traded from Pittsburgh Pirates to St. Louis Cardinals for Jack Wilson | MLB |
| 2000-07-29 | Jack Wilson | Pittsburgh Pirates | Traded from St. Louis Cardinals to Pittsburgh Pirates for Jason Christiansen | MLB |
| 2000-07-30 | Scott Linebrink | Houston Astros | Traded from Giants to Astros for Doug Henry | MLB |
| 2000-07-30 | Doug Henry | San Francisco Giants | Traded from Houston Astros to San Francisco Giants for Scott Linebrink | MLB |
| 2000-07-31 | Gabe Molina | Atlanta Braves | Traded from Baltimore Orioles with B.J. Surhoff to Atlanta Braves for Trenidad Hubbard, Fernando Lunar and Luis Rivera | MLB |
| 2000-07-31 | B.J. Surhoff | Atlanta Braves | Traded from Baltimore Orioles with Gabe Molina to Atlanta Braves for Trenidad Hubbard, Fernando Lunar and Luis Rivera | MLB |
| 2000-07-31 | Trenidad Hubbard | Baltimore Orioles | Traded from Atlanta Braves with Fernando Lunar and Luis Rivera to Baltimore Orioles for Gabe Molina and B.J. Surhoff | MLB |
| 2000-07-31 | Fernando Lunar | Baltimore Orioles | Traded from Atlanta Braves with Trenidad Hubbard and Luis Rivera to Baltimore Orioles for Gabe Molina and B.J. Surhoff | MLB |
| 2000-07-31 | Luis Rivera | Baltimore Orioles | Traded from Atlanta Braves with Trenidad Hubbard and Fernando Lunar to Baltimore Orioles for Gabe Molina and B.J. Surhoff | MLB |
| 2000-07-31 | Will Clark | St. Louis Cardinals | Traded from Baltimore Orioles to St. Louis Cardinals for Jose Leon | MLB |
| 2000-07-31 | Jose Leon | Baltimore Orioles | Traded from St. Louis Cardinals to Baltimore Orioles for Will Clark | MLB |
| 2000-07-31 | Jay Witasick | San Diego Padres | Traded from Kansas City Royals to San Diego Padres for Brian Meadows | MLB |
| 2000-07-31 | Brian Meadows | Kansas City Royals | Traded from San Diego Padres to Kansas City Royals for Jay Witasick | MLB |
| 2000-07-31 | Danny Ardoin | Minnesota Twins | Traded from Oakland Athletics to Minnesota Twins for Mario Valdez | MLB |
| 2000-07-31 | Mario Valdez | Oakland Athletics | Traded from Minnesota Twins to Oakland Athletics for Danny Ardoin | MLB |
| 2000-07-31 | Tom Davey | San Diego Padres | Traded from Seattle Mariners with John Mabry to San Diego Padres for Al Martin | MLB |
| 2000-07-31 | John Mabry | San Diego Padres | Traded from Seattle Mariners with Tom Davey to San Diego Padres for Al Martin | MLB |
| 2000-07-31 | Al Martin | Seattle Mariners | Traded from San Diego Padres to Seattle Mariners for Tom Davey and John Mabry | MLB |
| 2000-07-31 | Mark Guthrie | Toronto Blue Jays | Traded from Tampa Bay Devil Rays with Steve Trachsel to Toronto Blue Jays for Brent Abernathy | MLB |
| 2000-07-31 | Steve Trachsel | Toronto Blue Jays | Traded from Tampa Bay Devil Rays with Mark Guthrie to Toronto Blue Jays for Brent Abernathy | MLB |
| 2000-07-31 | Brent Abernathy | Tampa Bay Devil Rays | Traded from Toronto Blue Jays to Tampa Bay Devil Rays for Mark Guthrie and Steve Trachsel | MLB |
| 2000-07-31 | Ross Gload | Chicago Cubs | Traded from Florida Marlins with Dave Noyce to Chicago Cubs for Henry Rodriguez | MLB |
| 2000-07-31 | Henry Rodriguez | Florida Marlins | Traded from Chicago Cubs to Florida Marlins for Ross Gload and Dave Noyce | MLB |
| 2000-07-31 | Rondell White | Chicago Cubs | Traded from Montreal Expos to Chicago Cubs for Scott Downs | MLB |
| 2000-07-31 | Scott Downs | Montreal Expos | Traded from Chicago Cubs to Montreal Expos for Rondell White | MLB |
| 2000-07-31 | Todd Hollandsworth | Colorado Rockies | Traded from Los Angeles Dodgers with Kevin Gibbs and Randey Dorame to Colorado Rockies for Tom Goodwin | MLB |
| 2000-07-31 | Tom Goodwin | Los Angeles Dodgers | Traded from Colorado Rockies to Los Angeles Dodgers for Todd Hollandsworth, Kevin Gibbs and Randey Dorame | MLB |
| 2000-07-31 | Anthony Shumaker | Baltimore Orioles | Traded from New York Mets to Baltimore Orioles for Juan Aracena | MLB |
| 2000-07-31 | Carlos Hernandez | St. Louis Cardinals | Traded from San Diego Padres with Nate Tebbs to St. Louis Cardinals for Heathcliff Slocumb and Ben Johnson | MLB |
| 2000-07-31 | Heathcliff Slocumb | San Diego Padres | Traded from St. Louis Cardinals with Ben Johnson to San Diego Padres for Carlos Hernandez and Nate Tebbs | MLB |
| 2000-07-31 | Ben Johnson | San Diego Padres | Traded from St. Louis Cardinals with Heathcliff Slocumb to San Diego Padres for Carlos Hernandez and Nate Tebbs | MLB |
| 2000-08-02 | Aaron Holbert | Florida Marlins | Traded from Boston Red Sox to Florida Marlins for Nelson Lara (3/30/2001) | MLB |
| 2000-08-04 | Dave Martinez | Toronto Blue Jays | Traded from Texas Rangers to Toronto Blue Jays for Pete Munro (8/8/2000) | MLB |
| 2000-08-04 | Desi Relaford | San Diego Padres | Traded from Philadelphia Phillies to San Diego Padres for David Newhan (8/7/2000) | MLB |
| 2000-08-05 | Mickey Morandini | Toronto Blue Jays | Traded from Philadelphia Phillies to Toronto Blue Jays for Rob Ducey (8/7/2000) | MLB |
| 2000-08-06 | Bruce Aven | Los Angeles Dodgers | Traded by Pittsburgh Pirates to Los Angeles Dodgers for future considerations | MLB |
| 2000-08-06 | Brian L. Hunter | Cincinnati Reds | Traded from Colorado Rockies to Cincinnati Reds for Robert Averette | MLB |
| 2000-08-07 | David Newhan | Philadelphia Phillies | Traded from San Diego Padres to Philadelphia Phillies for Desi Relaford (8/4/2000) | MLB |
| 2000-08-07 | Rob Ducey | Philadelphia Phillies | Traded from Toronto Blue Jays to Philadelphia Phillies for Mickey Morandini (8/5/2000) | MLB |
| 2000-08-07 | Chris Spurling | Pittsburgh Pirates | Traded from New York Yankees to Pittsburgh Pirates for Luis Sojo | MLB |
| 2000-08-07 | Luis Sojo | New York Yankees | Traded from Pittsburgh Pirates to New York Yankees for Chris Spurling | MLB |
| 2000-08-08 | Pete Munro | Texas Rangers | Traded from Toronto Blue Jays to Texas Rangers for Dave Martinez (8/4/2000) | MLB |
| 2000-08-08 | Chris Widger | Seattle Mariners | Traded from Montreal Expos to Seattle Mariners for Sean Spencer (8/10/2000) and Terrmel Sledge (9/28/2000) | MLB |
| 2000-08-10 | Sean Spencer | Montreal Expos | Traded from Seattle Mariners with Terrmel Sledge to Montreal Expos for Chris Widger (8/8/2000) | MLB |
| 2000-08-11 | Wilson Delgado | Kansas City Royals | Traded from New York Yankees to Kansas City Royals for Nick Ortiz | MLB |
| 2000-08-12 | Jarrod Patterson | Montreal Expos | Traded from Pittsburgh Pirates to Montreal Expos for Matt Skrmetta | MLB |
| 2000-08-12 | Matt Skrmetta | Pittsburgh Pirates | Traded from Montreal Expos to Pittsburgh Pirates for Jarrod Patterson | MLB |
| 2000-08-22 | Scott Karl | Anaheim Angels | Traded by Colorado Rockies to Anaheim Angels for future considerations | MLB |
| 2000-08-23 | Alan Zinter | Arizona Diamondbacks | Traded by Chicago Cubs to Arizona Diamondbacks for future considerations | MLB |
| 2000-08-23 | Eddie Zosky | Houston Astros | Traded by Pittsburgh Pirates to Houston Astros for future considerations | MLB |
| 2000-08-30 | Marco Scutaro | Milwaukee Brewers | Traded from Cleveland Indians with Paul Rigdon, Richie Sexson and Kane Davis to Milwaukee Brewers for Bob Wickman (7/28/2000), Steve Woodard (7/28/2000) and Jason Bere (7/28/2000) | MLB |
| 2000-08-30 | Nelson Cruz | Oakland Athletics | Traded from New York Mets to Oakland Athletics for Jorge Velandia | MLB |
| 2000-08-30 | Jorge Velandia | New York Mets | Traded from Oakland Athletics to New York Mets for Nelson Cruz | MLB |
| 2000-08-31 | Midre Cummings | Boston Red Sox | Traded from Minnesota Twins to Boston Red Sox for Hector De Los Santos | MLB |
| 2000-08-31 | Chris Reitsma | Cincinnati Reds | Traded from Boston Red Sox with John Curtice to Cincinnati Reds for Dante Bichette | MLB |
| 2000-08-31 | Dante Bichette | Boston Red Sox | Traded from Cincinnati Reds to Boston Red Sox for Chris Reitsma and John Curtice | MLB |
| 2000-09-09 | Lew Ford | Minnesota Twins | Traded from Boston Red Sox to Minnesota Twins for Hector Carrasco | MLB |
| 2000-09-09 | Hector Carrasco | Boston Red Sox | Traded from Minnesota Twins to Boston Red Sox for Lew Ford | MLB |
| 2000-09-20 | Jesus Pena | Boston Red Sox | Traded from Chicago White Sox to Boston Red Sox for Mike Rupp (3/19/2001) | MLB |
| 2000-09-28 | Terrmel Sledge | Montreal Expos | Traded from Seattle Mariners with Sean Spencer to Montreal Expos for Chris Widger (8/8/2000) | MLB |
| 2000-11-07 | Gary Glover | Chicago White Sox | Traded from Toronto Blue Jays to Chicago White Sox for Scott Eyre | MLB |
| 2000-11-07 | Scott Eyre | Toronto Blue Jays | Traded from Chicago White Sox to Toronto Blue Jays for Gary Glover | MLB |
| 2000-11-08 | Ron Villone | Colorado Rockies | Traded from Cincinnati Reds to Colorado Rockies for Justin Carter (12/20/2000) and Jeff Taglienti (12/20/2000) | MLB |
| 2000-11-16 | Jim Brower | Cincinnati Reds | Traded from Cleveland Indians with Rob Pugmire to Cincinnati Reds for Eddie Taubensee | MLB |
| 2000-11-16 | Eddie Taubensee | Cleveland Indians | Traded from Cincinnati Reds to Cleveland Indians for Jim Brower and Rob Pugmire | MLB |
| 2000-11-16 | Michael Coleman | Cincinnati Reds | Traded from Boston Red Sox with Donnie Sadler to Cincinnati Reds for Chris Stynes | MLB |
| 2000-11-16 | Donnie Sadler | Cincinnati Reds | Traded from Boston Red Sox with Michael Coleman to Cincinnati Reds for Chris Stynes | MLB |
| 2000-11-16 | Chris Stynes | Boston Red Sox | Traded from Cincinnati Reds to Boston Red Sox for Michael Coleman and Donnie Sadler | MLB |
| 2000-11-17 | Aaron Harang | Oakland Athletics | Traded from Texas Rangers with Ryan Cullen to Oakland Athletics for Randy Velarde | MLB |
| 2000-11-17 | Randy Velarde | Texas Rangers | Traded from Oakland Athletics to Texas Rangers for Ryan Cullen and Aaron Harang | MLB |
| 2000-11-18 | Bill Mueller | Chicago Cubs | Traded from San Francisco Giants to Chicago Cubs for Tim Worrell | MLB |
| 2000-11-18 | Tim Worrell | San Francisco Giants | Traded from Chicago Cubs to San Francisco Giants for Bill Mueller | MLB |
| 2000-11-20 | Matt Stairs | Chicago Cubs | Traded from Oakland Athletics to Chicago Cubs for Eric Ireland | MLB |
| 2000-11-22 | Clayton Andrews | Cincinnati Reds | Traded from Toronto Blue Jays with Leo Estrella to Cincinnati Reds for Steve Parris | MLB |
| 2000-11-22 | Leo Estrella | Cincinnati Reds | Traded from Toronto Blue Jays with Clayton Andrews to Cincinnati Reds for Steve Parris | MLB |
| 2000-11-22 | Steve Parris | Toronto Blue Jays | Traded from Cincinnati Reds to Toronto Blue Jays for Clayton Andrews and Leo Estrella | MLB |
| 2000-11-27 | Amaury Garcia | Chicago White Sox | Traded from Florida Marlins to Chicago White Sox for Mark Roberts (12/11/2000) | MLB |
| 2000-12-01 | Santiago Perez | San Diego Padres | Traded from Milwaukee Brewers with Chad Green to San Diego Padres for Brandon Kolb and Will Cunnane (12/20/2000) | MLB |
| 2000-12-01 | Brandon Kolb | Milwaukee Brewers | Traded from San Diego Padres with Will Cunnane to Milwaukee Brewers for Santiago Perez and Chad Green (12/20/2000) | MLB |
| 2000-12-07 | Chad Bradford | Oakland Athletics | Traded from Chicago White Sox to Oakland Athletics for Miguel Olivo (12/13/2000) | MLB |
| 2000-12-09 | Seth Etherton | Cincinnati Reds | Traded from Anaheim Angels to Cincinnati Reds for Wilmy Caceres | MLB |
| 2000-12-09 | Jeff Abbott | Florida Marlins | Traded from Chicago White Sox to Florida Marlins for Julio Ramirez | MLB |
| 2000-12-09 | Julio Ramirez | Chicago White Sox | Traded from Florida Marlins to Chicago White Sox for Jeff Abbott | MLB |
| 2000-12-11 | John Bale | Baltimore Orioles | Traded from Toronto Blue Jays to Baltimore Orioles for Jayson Werth | MLB |
| 2000-12-11 | Jayson Werth | Toronto Blue Jays | Traded from Baltimore Orioles to Toronto Blue Jays for John Bale | MLB |
| 2000-12-11 | Brad Ausmus | Houston Astros | Traded from Detroit Tigers with Doug Brocail and Nelson Cruz to Houston Astros for Roger Cedeno, Chris Holt and Mitch Meluskey | MLB |
| 2000-12-11 | Doug Brocail | Houston Astros | Traded from Detroit Tigers with Brad Ausmus and Nelson Cruz to Houston Astros for Roger Cedeno, Chris Holt and Mitch Meluskey | MLB |
| 2000-12-11 | Nelson Cruz | Houston Astros | Traded from Detroit Tigers with Brad Ausmus and Doug Brocail to Houston Astros for Roger Cedeno, Chris Holt and Mitch Meluskey | MLB |
| 2000-12-11 | Roger Cedeno | Detroit Tigers | Traded from Houston Astros with Chris Holt and Mitch Meluskey to Detroit Tigers for Brad Ausmus, Doug Brocail and Nelson Cruz | MLB |
| 2000-12-11 | Chris Holt | Detroit Tigers | Traded from Houston Astros with Roger Cedeno and Mitch Meluskey to Detroit Tigers for Brad Ausmus, Doug Brocail and Nelson Cruz | MLB |
| 2000-12-11 | Mitch Meluskey | Detroit Tigers | Traded from Houston Astros with Roger Cedeno and Chris Holt to Detroit Tigers for Brad Ausmus, Doug Brocail and Nelson Cruz | MLB |
| 2000-12-11 | Bubba Trammell | San Diego Padres | Traded from New York Mets to San Diego Padres for Donne Wall | MLB |
| 2000-12-11 | Donne Wall | New York Mets | Traded from San Diego Padres to New York Mets for Bubba Trammell | MLB |
| 2000-12-13 | Miguel Olivo | Chicago White Sox | Traded from Oakland Athletics to Chicago White Sox for Chad Bradford (12/7/2000) | MLB |
| 2000-12-14 | Aaron Myette | Texas Rangers | Traded from Chicago White Sox with Brian Schmack to Texas Rangers for Royce Clayton | MLB |
| 2000-12-14 | Brian Schmack | Texas Rangers | Traded from Chicago White Sox with Aaron Myette to Texas Rangers for Royce Clayton | MLB |
| 2000-12-14 | Royce Clayton | Chicago White Sox | Traded from Texas Rangers to Chicago White Sox for Aaron Myette and Brian Schmack | MLB |
| 2000-12-14 | Britt Reames | Montreal Expos | Traded from St. Louis Cardinals with Fernando Tatis to Montreal Expos for Dustin Hermanson and Steve Kline | MLB |
| 2000-12-14 | Fernando Tatis | Montreal Expos | Traded from St. Louis Cardinals with Britt Reames to Montreal Expos for Dustin Hermanson and Steve Kline | MLB |
| 2000-12-14 | Dustin Hermanson | St. Louis Cardinals | Traded from Montreal Expos with Steve Kline to St. Louis Cardinals for Britt Reames and Fernando Tatis | MLB |
| 2000-12-14 | Steve Kline | St. Louis Cardinals | Traded from Montreal Expos with Dustin Hermanson to St. Louis Cardinals for Britt Reames and Fernando Tatis | MLB |
| 2000-12-15 | Brandon Villafuerte | Texas Rangers | Traded from Detroit Tigers with Kevin Mobley to Texas Rangers for Matt Perisho | MLB |
| 2000-12-15 | Matt Perisho | Detroit Tigers | Traded from Texas Rangers to Detroit Tigers for Brandon Villafuerte and Kevin Mobley | MLB |
| 2000-12-18 | Jesse Garcia | Atlanta Braves | Traded from Baltimore Orioles to Atlanta Braves for Steve Sisco | MLB |
| 2000-12-18 | Steve Sisco | Baltimore Orioles | Traded from Atlanta Braves to Baltimore Orioles for Jesse Garcia | MLB |
| 2000-12-20 | Will Cunnane | Milwaukee Brewers | Traded from San Diego Padres with Brandon Kolb to Milwaukee Brewers for Santiago Perez (12/1/2000) and Chad Green | MLB |
| 2000-12-22 | Ryan Minor | Montreal Expos | Traded from Baltimore Orioles to Montreal Expos for Jorge Julio | MLB |
| 2000-12-22 | Jorge Julio | Baltimore Orioles | Traded from Montreal Expos to Baltimore Orioles for Ryan Minor | MLB |
| 264 record(s) |