| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 19 | Tommy Edman | 26 | 2B | B | 97 | 159 | 641 | 91 | 168 | 41 | 3 | 11 | 56 | 30 | 5 | 38 | 95 | 6 | 2 | 4 | 1 | 4 | 248 | 691 | 55 | 113 | .262 | .308 | .387 | .695 | .223 | .125 | .291 | 5.50 | 13.75 | 2.50 | 58.27 | 2016- 6- 196-SLN | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 46 | Paul Goldschmidt | 33 | 1B | R | 120 | 158 | 603 | 102 | 177 | 36 | 2 | 31 | 99 | 12 | 0 | 67 | 136 | 4 | 0 | 5 | 2 | 13 | 310 | 679 | 69 | 108 | .294 | .365 | .514 | .879 | .352 | .220 | .331 | 9.87 | 20.03 | 2.03 | 19.45 | 2009- 8- 246-ARI | premium | premium | premium | MLB | 2011-2025 | 2007-2025 | 2021 |
| 28 | Nolan Arenado | 30 | 3B | R | 107 | 157 | 593 | 81 | 151 | 34 | 3 | 34 | 105 | 2 | 0 | 50 | 96 | 3 | 0 | 7 | 8 | 20 | 293 | 653 | 71 | 80 | .255 | .312 | .494 | .806 | .327 | .239 | .249 | 7.66 | 14.70 | 1.92 | 17.44 | 2009- 2- 59-COL | premium | premium | premium | MLB | 2013-2025 | 2009-2025 | 2021 |
| 3 | Dylan Carlson | 22 | RF-CF | B | 106 | 149 | 542 | 79 | 144 | 31 | 4 | 18 | 65 | 2 | 1 | 57 | 152 | 11 | 1 | 8 | 2 | 5 | 237 | 619 | 53 | 91 | .266 | .343 | .437 | .780 | .279 | .171 | .332 | 9.21 | 24.56 | 2.67 | 30.11 | 2016- 1- 33-SLN | premium | premium | premium | MLB | 2020-2025 | 2016-2025 | 2021 |
| 27 | Tyler O'Neill | 26 | LF | R | 123 | 138 | 482 | 89 | 138 | 26 | 2 | 34 | 80 | 15 | 4 | 38 | 168 | 13 | 0 | 4 | 0 | 8 | 270 | 537 | 62 | 76 | .286 | .352 | .560 | .912 | .376 | .274 | .366 | 7.08 | 31.28 | 4.42 | 14.18 | 2013- 3- 85-SEA | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 4 | Yadier Molina | 38 | C | R | 92 | 121 | 440 | 45 | 111 | 19 | 0 | 11 | 66 | 3 | 0 | 24 | 79 | 5 | 0 | 3 | 1 | 16 | 163 | 472 | 30 | 81 | .252 | .297 | .370 | .667 | .180 | .118 | .283 | 5.08 | 16.74 | 3.29 | 40.00 | 2000- 4- 113-SLN | premium | premium | premium | MLB | 2004-2022 | 2001-2022 | 2021 |
| 48 | Harrison Bader | 27 | CF | R | 105 | 103 | 367 | 45 | 98 | 21 | 1 | 16 | 50 | 9 | 4 | 27 | 85 | 5 | 0 | 2 | 6 | 4 | 169 | 401 | 38 | 60 | .267 | .324 | .460 | .784 | .281 | .193 | .306 | 6.73 | 21.20 | 3.15 | 22.94 | 2015- 3- 100-SLN | premium | premium | premium | MLB | 2017-2025 | 2013-2025 | 2021 |
| 11 | Paul DeJong | 27 | SS | R | 94 | 113 | 356 | 44 | 70 | 10 | 1 | 19 | 45 | 4 | 1 | 35 | 103 | 9 | 0 | 2 | 0 | 6 | 139 | 402 | 30 | 40 | .197 | .284 | .390 | .674 | .301 | .193 | .216 | 8.71 | 25.62 | 2.94 | 18.74 | 2015- 4- 131-SLN | premium | premium | premium | MLB | 2017-2025 | 2013-2025 | 2021 |
| 63 | Edmundo Sosa | 25 | SS | R | 101 | 113 | 288 | 39 | 78 | 8 | 4 | 6 | 27 | 4 | 4 | 17 | 63 | 17 | 1 | 2 | 2 | 8 | 112 | 325 | 18 | 60 | .271 | .346 | .389 | .735 | .177 | .118 | .326 | 5.23 | 19.38 | 3.71 | 48.00 | 2012- UDFA -SLN | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 13 | Matt Carpenter | 35 | 2B | L | 85 | 130 | 207 | 18 | 35 | 11 | 1 | 3 | 21 | 2 | 0 | 35 | 77 | 6 | 0 | 1 | 1 | 1 | 57 | 249 | 15 | 20 | .169 | .305 | .275 | .580 | .285 | .106 | .250 | 14.06 | 30.92 | 2.20 | 69.00 | 2009- 13- 399-SLN | premium | premium | premium | MLB | 2011-2024 | 2005-2024 | 2021 |
| 7 | Andrew Knizner | 26 | C | R | 75* | 63 | 161 | 18 | 28 | 7 | 0 | 1 | 9 | 0 | 0 | 20 | 39 | 4 | 0 | 0 | 2 | 7 | 38 | 185 | 8 | 20 | .174 | .281 | .236 | .517 | .186 | .062 | .223 | 10.81 | 21.08 | 1.95 | 161.00 | 2016- 7- 226-SLN | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 26 | Justin Williams | 25 | RF-LF | L | 72* | 51 | 119 | 10 | 19 | 0 | 0 | 4 | 11 | 0 | 1 | 17 | 46 | 1 | 0 | 0 | 5 | 2 | 31 | 137 | 4 | 15 | .160 | .270 | .261 | .531 | .235 | .101 | .217 | 12.41 | 33.58 | 2.71 | 29.75 | 2013- 2- 52-ARI | premium | premium | premium | MLB | 2018-2021 | 2013-2025 | 2021 |
| 68 | Lars Nootbaar | 23 | RF | L | 100* | 58 | 109 | 15 | 26 | 3 | 1 | 5 | 15 | 2 | 1 | 13 | 28 | 0 | 1 | 1 | 1 | 0 | 46 | 124 | 9 | 17 | .239 | .317 | .422 | .739 | .312 | .183 | .273 | 10.48 | 22.58 | 2.15 | 21.80 | 2018- 8- 243-SLN | premium | premium | premium | MLB | 2021-2025 | 2016-2025 | 2021 |
| 64 | Jose Rondon | 27 | RF-3B | R | 63 | 80 | 13 | 21 | 3 | 0 | 3 | 9 | 2 | 0 | 8 | 17 | 0 | 0 | 2 | 0 | 1 | 33 | 90 | 6 | 15 | .263 | .322 | .413 | .735 | .275 | .150 | .290 | 8.89 | 18.89 | 2.13 | 26.67 | 2011- UDFA -ANA | premium | premium | premium | MLB | 2016-2021 | 2011-2025 | 2021 | |
| 50 | Adam Wainwright | 39 | P | R | 33 | 57 | 1 | 7 | 2 | 0 | 0 | 4 | 0 | 0 | 3 | 25 | 0 | 14 | 0 | 0 | 2 | 9 | 74 | 2 | 5 | .123 | .167 | .158 | .325 | .088 | .035 | .219 | 4.05 | 33.78 | 8.33 | 0.00 | 2000- 1- 29-ATL | premium | premium | premium | MLB | 2005-2023 | 2000-2023 | 2021 | |
| 35 | Lane Thomas | 25 | RF-LF | R | 104 | 32 | 48 | 2 | 5 | 1 | 0 | 0 | 1 | 2 | 1 | 10 | 17 | 0 | 0 | 0 | 1 | 1 | 6 | 58 | 1 | 4 | .104 | .259 | .125 | .384 | .250 | .021 | .161 | 17.24 | 29.31 | 1.70 | 0.00 | 2014- 5- 144-TOR | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 0 | Austin Dean | 27 | LF-RF | R | 22 | 30 | 5 | 7 | 2 | 0 | 1 | 7 | 0 | 0 | 6 | 11 | 0 | 0 | 2 | 0 | 0 | 12 | 38 | 3 | 4 | .233 | .342 | .400 | .742 | .367 | .167 | .300 | 15.79 | 28.95 | 1.83 | 30.00 | 2012- 4- 137-MIA | premium | premium | premium | MLB | 2018-2022 | 2012-2022 | 2021 | |
| 33 | Kwang Hyun Kim | 32 | P | L | 25 | 26 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 9 | 1 | 2 | 0 | 0 | 0 | 4 | 29 | 1 | 2 | .115 | .148 | .154 | .302 | .038 | .039 | .176 | 0.00 | 31.03 | 0.00 | 0.00 | 2019- UDFA -SLN | premium | premium | premium | MLB | 2020-2021 | 2020-2021 | 2021 | |
| 18 | Carlos Martinez | 29 | P | R | 16 | 24 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 15 | 0 | 1 | 0 | 0 | 0 | 3 | 25 | 1 | 1 | .083 | .083 | .125 | .208 | .042 | .042 | .222 | 0.00 | 60.00 | 0.00 | 0.00 | 2009- UDFA -SLN | premium | premium | premium | MLB | 2013-2021 | 2010-2024 | 2021 | |
| 34 | Jon Lester | 37 | P | L | 11 | 20 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 11 | 0 | 0 | 0 | 0 | 0 | 5 | 22 | 2 | 1 | .150 | .227 | .250 | .477 | .200 | .100 | .333 | 9.09 | 50.00 | 5.50 | 0.00 | 2002- 2- 57-BOS | premium | premium | premium | MLB | 2006-2021 | 2002-2021 | 2021 | |
| 59 | Johan Oviedo | 23 | P | R | 13 | 20 | 3 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 9 | 0 | 0 | 0 | 0 | 0 | 3 | 22 | 0 | 3 | .150 | .227 | .150 | .377 | .100 | .000 | .273 | 9.09 | 40.91 | 4.50 | 0.00 | 2016- UDFA -SLN | premium | premium | premium | MLB | 2020-2025 | 2016-2025 | 2021 | |
| 40 | Jake Woodford | 24 | P | R | 24 | 18 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 0 | 2 | 0 | 0 | 0 | 2 | 20 | 0 | 2 | .111 | .111 | .111 | .222 | .000 | .000 | .222 | 0.00 | 45.00 | 0.00 | 0.00 | 2015- 1- 39-SLN | premium | premium | premium | MLB | 2020-2025 | 2015-2025 | 2021 | |
| 34 | John Nogowski | 28 | 1B | R | 85* | 19 | 18 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 0 | 0 | 0 | 1 | 1 | 20 | 0 | 1 | .056 | .150 | .056 | .206 | .056 | .000 | .063 | 5.00 | 10.00 | 2.00 | 0.00 | 2014- 34-1032-OAK | premium | premium | premium | MLB | 2020-2021 | 2012-2025 | 2021 |
| 22 | Jack Flaherty | 25 | P | R | 15 | 17 | 2 | 2 | 0 | 0 | 1 | 3 | 0 | 0 | 5 | 7 | 0 | 3 | 1 | 0 | 0 | 5 | 26 | 1 | 1 | .118 | .304 | .294 | .598 | .471 | .176 | .100 | 19.23 | 26.92 | 1.40 | 17.00 | 2014- 1- 34-SLN | premium | premium | premium | MLB | 2017-2025 | 2014-2025 | 2021 | |
| 67 | Max Moroff | 28 | 2B | B | 6 | 16 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 16 | 0 | 1 | .063 | .063 | .063 | .126 | .000 | .000 | .167 | 0.00 | 62.50 | 0.00 | 0.00 | 2012- 16- 496-PIT | premium | premium | premium | MLB | 2016-2021 | 2012-2021 | 2021 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 33 | J.A. Happ | 38 | P | L | 10 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 15 | 0 | 0 | .000 | .067 | .000 | .067 | .071 | .000 | .000 | 6.67 | 33.33 | 5.00 | 0.00 | 2004- 3- 92-PHI | premium | premium | premium | MLB | 2007-2021 | 2002-2021 | 2021 | |
| 33 | John Gant | 28 | P | R | 22 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 5 | 0 | 0 | 0 | 0 | 18 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 44.44 | 0.00 | 0.00 | 2011- 21- 642-NYN | premium | premium | premium | MLB | 2016-2021 | 2011-2025 | 2021 | |
| 49 | Wade LeBlanc | 36 | P | L | 11 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 2 | 0 | 0 | 0 | 0 | 13 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 23.08 | 0.00 | 0.00 | 2006- 2- 61-SDN | premium | premium | premium | MLB | 2008-2021 | 2004-2021 | 2021 | |
| 39 | Miles Mikolas | 32 | P | R | 9 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 6 | 0 | 0 | 0 | 0 | 15 | 0 | 0 | .000 | .111 | .000 | .111 | .125 | .000 | .000 | 6.67 | 33.33 | 5.00 | 0.00 | 2009- 7- 204-SDN | premium | premium | premium | MLB | 2012-2025 | 2009-2025 | 2021 | |
| 32 | Daniel Ponce de Leon | 29 | P | R | 22 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2014- 9- 285-SLN | premium | premium | premium | MLB | 2018-2021 | 2011-2024 | 2021 | |
| 36 | Scott Hurst | 25 | CF | L | 7 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 20.00 | 0.00 | 0.00 | 2017- 3- 94-SLN | premium | premium | premium | MLB | 2021-2021 | 2015-2023 | 2021 | |
| 41 | Ali Sanchez | 24 | C | R | 2 | 4 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 4 | 2 | 0 | .500 | .500 | 1.000 | 1.500 | .500 | .500 | .500 | 0.00 | 0.00 | 0.00 | 0.00 | 2013- UDFA -NYN | premium | premium | premium | MLB | 2020-2025 | 2014-2025 | 2021 | |
| 43 | Dakota Hudson | 26 | P | R | 2 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .333 | .500 | .333 | .833 | .333 | .000 | 1.000 | 25.00 | 50.00 | 2.00 | 0.00 | 2016- 1- 34-SLN | premium | premium | premium | MLB | 2018-2024 | 2014-2025 | 2021 | |
| 61 | Seth Elledge | 25 | P | R | 11 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2017- 4- 123-SEA | premium | premium | premium | MLB | 2020-2021 | 2015-2024 | 2021 | |
| 29 | Alex Reyes | 26 | P | R | 67 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2012- UDFA -SLN | premium | premium | premium | MLB | 2016-2021 | 2013-2021 | 2021 | |
| 30 | Tyler Webb | 30 | P | L | 21 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2013- 10- 314-NYA | premium | premium | premium | MLB | 2017-2021 | 2010-2022 | 2021 | |
| 49 | Brandon Waddell | 27 | P | L | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2015- 5- 157-PIT | premium | premium | premium | MLB | 2020-2025 | 2013-2025 | 2021 | |
| 44 | Junior Fernandez | 24 | P | R | 16 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2014- UDFA -SLN | premium | premium | premium | MLB | 2019-2022 | 2014-2025 | 2021 | |
| Totals: | 1996 | 5351 | 706 | 1303 | 261 | 22 | 198 | 678 | 89 | 22 | 478 | 1341 | 86 | 40 | 44 | 32 | 99 | 2202 | 5999 | 481 | 822 | .244 | .313 | .412 | .725 | .270 | .168 | .287 | 7.97 | 22.35 | 2.81 | 27.03 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 18 | Carlos Martinez | 29 | R | 4 | 9 | 6.23 | 16 | 16 | 0 | 0 | 0 | 0 | 0 | 82.1 | 77 | 58 | 57 | 8 | 36 | 57 | 3 | 0 | 11 | 1.37 | 8.42 | 0.87 | 3.94 | 6.23 | 6.34 | 1.58 | 2009- UDFA -SLN | premium | premium | premium | MLB | 2013-2021 | 2010-2024 | 2021 |
| 65 | Giovanny Gallegos | 29 | R | 6 | 5 | 3.02 | 73 | 0 | 0 | 0 | 73 | 20 | 14 | 80.1 | 51 | 28 | 27 | 6 | 20 | 95 | 4 | 0 | 6 | 0.88 | 5.71 | 0.67 | 2.24 | 10.64 | 3.14 | 4.75 | 2011- UDFA -NYA | premium | premium | premium | MLB | 2017-2024 | 2012-2024 | 2021 |
| 43 | Dakota Hudson | 26 | R | 1 | 0 | 2.08 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 8.2 | 7 | 2 | 2 | 0 | 1 | 6 | 1 | 0 | 1 | 0.92 | 7.27 | 0.00 | 1.04 | 6.23 | 2.08 | 6.00 | 2016- 1- 34-SLN | premium | premium | premium | MLB | 2018-2024 | 2014-2025 | 2021 |
| 22 | Jack Flaherty | 25 | R | 9 | 2 | 3.22 | 17 | 15 | 0 | 0 | 2 | 0 | 0 | 78.1 | 57 | 35 | 28 | 12 | 26 | 85 | 4 | 0 | 6 | 1.06 | 6.55 | 1.38 | 2.99 | 9.77 | 4.02 | 3.27 | 2014- 1- 34-SLN | premium | premium | premium | MLB | 2017-2025 | 2014-2025 | 2021 |
| 33 | John Gant | 28 | R | 4 | 6 | 3.42 | 25 | 14 | 0 | 0 | 11 | 4 | 0 | 76.1 | 64 | 32 | 29 | 6 | 56 | 56 | 0 | 0 | 5 | 1.57 | 7.55 | 0.71 | 6.60 | 6.60 | 3.77 | 1.00 | 2011- 21- 642-NYN | premium | premium | premium | MLB | 2016-2021 | 2011-2025 | 2021 |
| 29 | Alex Reyes | 26 | R | 10 | 8 | 3.24 | 69 | 0 | 0 | 0 | 69 | 54 | 29 | 72.1 | 46 | 32 | 26 | 9 | 52 | 95 | 10 | 1 | 2 | 1.35 | 5.72 | 1.12 | 6.47 | 11.82 | 3.98 | 1.83 | 2012- UDFA -SLN | premium | premium | premium | MLB | 2016-2021 | 2013-2021 | 2021 |
| 92 | Genesis Cabrera | 24 | L | 4 | 5 | 3.73 | 71 | 0 | 0 | 0 | 71 | 5 | 0 | 70.0 | 52 | 31 | 29 | 3 | 36 | 77 | 9 | 0 | 5 | 1.26 | 6.69 | 0.39 | 4.63 | 9.90 | 3.99 | 2.14 | 2013- UDFA -TBA | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 40 | Jake Woodford | 24 | R | 3 | 4 | 3.99 | 26 | 8 | 0 | 0 | 18 | 4 | 0 | 67.2 | 66 | 32 | 30 | 7 | 25 | 50 | 2 | 0 | 8 | 1.34 | 8.78 | 0.93 | 3.33 | 6.65 | 4.26 | 2.00 | 2015- 1- 39-SLN | premium | premium | premium | MLB | 2020-2025 | 2015-2025 | 2021 |
| 34 | Jon Lester | 37 | L | 4 | 1 | 4.36 | 12 | 12 | 0 | 0 | 0 | 0 | 0 | 66.0 | 68 | 34 | 32 | 11 | 26 | 40 | 0 | 0 | 2 | 1.42 | 9.27 | 1.50 | 3.55 | 5.45 | 4.64 | 1.54 | 2002- 2- 57-BOS | premium | premium | premium | MLB | 2006-2021 | 2002-2021 | 2021 |
| 59 | Johan Oviedo | 23 | R | 0 | 5 | 4.91 | 14 | 13 | 0 | 0 | 1 | 0 | 0 | 62.1 | 61 | 39 | 34 | 8 | 37 | 51 | 2 | 0 | 6 | 1.57 | 8.81 | 1.16 | 5.34 | 7.36 | 5.63 | 1.38 | 2016- UDFA -SLN | premium | premium | premium | MLB | 2020-2025 | 2016-2025 | 2021 |
| 33 | J.A. Happ | 38 | L | 5 | 2 | 4.00 | 11 | 11 | 0 | 0 | 0 | 0 | 0 | 54.0 | 52 | 24 | 24 | 9 | 17 | 45 | 1 | 0 | 0 | 1.28 | 8.67 | 1.50 | 2.83 | 7.50 | 4.00 | 2.65 | 2004- 3- 92-PHI | premium | premium | premium | MLB | 2007-2021 | 2002-2021 | 2021 |
| 56 | Ryan Helsley | 26 | R | 6 | 4 | 4.56 | 51 | 0 | 0 | 0 | 51 | 7 | 1 | 47.1 | 40 | 24 | 24 | 4 | 27 | 47 | 7 | 0 | 0 | 1.42 | 7.61 | 0.76 | 5.13 | 8.94 | 4.56 | 1.74 | 2015- 5- 161-SLN | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 39 | Miles Mikolas | 32 | R | 2 | 3 | 4.23 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 44.2 | 43 | 24 | 21 | 6 | 11 | 31 | 1 | 0 | 2 | 1.21 | 8.66 | 1.21 | 2.22 | 6.25 | 4.84 | 2.82 | 2009- 7- 204-SDN | premium | premium | premium | MLB | 2012-2025 | 2009-2025 | 2021 |
| 49 | Wade LeBlanc | 36 | L | 0 | 1 | 3.61 | 12 | 8 | 0 | 0 | 4 | 1 | 0 | 42.1 | 45 | 17 | 17 | 7 | 16 | 23 | 0 | 0 | 3 | 1.44 | 9.57 | 1.49 | 3.40 | 4.89 | 3.61 | 1.44 | 2006- 2- 61-SDN | premium | premium | premium | MLB | 2008-2021 | 2004-2021 | 2021 |
| 49 | Brandon Waddell | 27 | L | 0 | 0 | 4.15 | 4 | 0 | 0 | 0 | 4 | 2 | 0 | 4.1 | 4 | 2 | 2 | 0 | 5 | 6 | 1 | 0 | 0 | 2.08 | 8.31 | 0.00 | 10.38 | 12.46 | 4.15 | 1.20 | 2015- 5- 157-PIT | premium | premium | premium | MLB | 2020-2025 | 2013-2025 | 2021 |
| 62 | T.J. McFarland | 32 | L | 4 | 1 | 2.56 | 38 | 0 | 0 | 0 | 38 | 7 | 0 | 38.2 | 32 | 11 | 11 | 3 | 9 | 21 | 0 | 0 | 0 | 1.06 | 7.45 | 0.70 | 2.09 | 4.89 | 2.56 | 2.33 | 2007- 4- 137-CLE | premium | premium | premium | MLB | 2013-2025 | 2008-2025 | 2021 |
| 21 | Andrew Miller | 36 | L | 0 | 0 | 4.75 | 40 | 0 | 0 | 0 | 40 | 6 | 0 | 36.0 | 41 | 19 | 19 | 5 | 16 | 40 | 1 | 0 | 5 | 1.58 | 10.25 | 1.25 | 4.00 | 10.00 | 4.75 | 2.50 | 2006- 1- 6-DET | premium | premium | premium | MLB | 2006-2021 | 2004-2021 | 2021 |
| 66 | Luis Garcia | 34 | R | 1 | 1 | 3.24 | 34 | 0 | 0 | 0 | 34 | 6 | 2 | 33.1 | 25 | 12 | 12 | 2 | 8 | 34 | 3 | 0 | 1 | 0.99 | 6.75 | 0.54 | 2.16 | 9.18 | 3.24 | 4.25 | 2004- UDFA -LAN | premium | premium | premium | MLB | 2013-2025 | 2007-2025 | 2021 |
| 32 | Daniel Ponce de Leon | 29 | R | 1 | 1 | 6.21 | 24 | 2 | 0 | 0 | 22 | 9 | 2 | 33.1 | 32 | 24 | 23 | 5 | 22 | 24 | 2 | 0 | 5 | 1.62 | 8.64 | 1.35 | 5.94 | 6.48 | 6.48 | 1.09 | 2014- 9- 285-SLN | premium | premium | premium | MLB | 2018-2021 | 2011-2024 | 2021 |
| 38 | Kodi Whitley | 26 | R | 0 | 0 | 2.49 | 25 | 0 | 0 | 0 | 25 | 6 | 0 | 25.1 | 15 | 8 | 7 | 1 | 12 | 27 | 1 | 1 | 0 | 1.07 | 5.33 | 0.36 | 4.26 | 9.59 | 2.84 | 2.25 | 2017- 27- 814-SLN | premium | premium | premium | MLB | 2020-2022 | 2014-2025 | 2021 |
| 50 | Adam Wainwright | 39 | R | 17 | 7 | 3.05 | 32 | 32 | 3 | 1 | 0 | 0 | 0 | 206.1 | 168 | 72 | 70 | 21 | 50 | 174 | 4 | 1 | 9 | 1.06 | 7.33 | 0.92 | 2.18 | 7.59 | 3.14 | 3.48 | 2000- 1- 29-ATL | premium | premium | premium | MLB | 2005-2023 | 2000-2023 | 2021 |
| 44 | Junior Fernandez | 24 | R | 1 | 0 | 5.66 | 18 | 0 | 0 | 0 | 18 | 11 | 0 | 20.2 | 25 | 13 | 13 | 2 | 15 | 15 | 1 | 1 | 0 | 1.94 | 10.89 | 0.87 | 6.53 | 6.53 | 5.66 | 1.00 | 2014- UDFA -SLN | premium | premium | premium | MLB | 2019-2022 | 2014-2025 | 2021 |
| 55 | Angel Rondon | 23 | R | 0 | 0 | 0.00 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 2.0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1.00 | 4.50 | 0.00 | 4.50 | 4.50 | 0.00 | 1.00 | 2016- UDFA -SLN | premium | premium | premium | MLB | 2021-2022 | 2016-2022 | 2021 |
| 53 | Brandon Dickson | 36 | R | 0 | 0 | 13.50 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 2.0 | 5 | 3 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | 2.50 | 22.50 | 4.50 | 0.00 | 4.50 | 13.50 | 0.00 | 2006- UDFA - | premium | premium | premium | MLB | 2011-2021 | 2006-2021 | 2021 |
| 30 | Tyler Webb | 30 | L | 0 | 0 | 13.22 | 22 | 0 | 0 | 0 | 22 | 4 | 0 | 16.1 | 22 | 26 | 24 | 1 | 19 | 14 | 1 | 0 | 0 | 2.51 | 12.12 | 0.55 | 10.47 | 7.71 | 14.33 | 0.74 | 2013- 10- 314-NYA | premium | premium | premium | MLB | 2017-2021 | 2010-2022 | 2021 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 60 | Justin Miller | 34 | R | 1 | 0 | 4.50 | 18 | 0 | 0 | 0 | 18 | 5 | 1 | 16.0 | 15 | 8 | 8 | 2 | 5 | 9 | 0 | 0 | 2 | 1.25 | 8.44 | 1.13 | 2.81 | 5.06 | 4.50 | 1.80 | 2008- 16- 483-TEX | premium | premium | premium | MLB | 2014-2021 | 2008-2022 | 2021 |
| 61 | Seth Elledge | 25 | R | 0 | 0 | 4.63 | 11 | 0 | 0 | 0 | 11 | 2 | 0 | 11.2 | 13 | 6 | 6 | 1 | 7 | 11 | 1 | 0 | 1 | 1.71 | 10.03 | 0.77 | 5.40 | 8.49 | 4.63 | 1.57 | 2017- 4- 123-SEA | premium | premium | premium | MLB | 2020-2021 | 2015-2024 | 2021 |
| 33 | Kwang Hyun Kim | 32 | L | 7 | 7 | 3.46 | 27 | 21 | 0 | 0 | 6 | 2 | 1 | 106.2 | 98 | 46 | 41 | 12 | 39 | 80 | 4 | 0 | 4 | 1.28 | 8.27 | 1.01 | 3.29 | 6.75 | 3.88 | 2.05 | 2019- UDFA -SLN | premium | premium | premium | MLB | 2020-2021 | 2020-2021 | 2021 |
| 12 | Jordan Hicks | 24 | R | 0 | 0 | 5.40 | 10 | 0 | 0 | 0 | 10 | 1 | 0 | 10.0 | 5 | 6 | 6 | 0 | 10 | 10 | 3 | 0 | 0 | 1.50 | 4.50 | 0.00 | 9.00 | 9.00 | 5.40 | 1.00 | 2015- 3- 105-SLN | premium | premium | premium | MLB | 2018-2025 | 2016-2025 | 2021 |
| 13 | Matt Carpenter | 35 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.50 | 13.50 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2009- 13- 399-SLN | premium | premium | premium | MLB | 2011-2024 | 2005-2024 | 2021 |
| 77 | Roel Ramirez | 26 | R | 0 | 0 | 81.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0.1 | 1 | 3 | 3 | 0 | 2 | 0 | 0 | 0 | 0 | 9.00 | 27.00 | 0.00 | 54.00 | 0.00 | 81.00 | 0.00 | 2013- 8- 248-TBA | premium | premium | premium | MLB | 2020-2021 | 2013-2025 | 2021 |
| 62 | Bernardo Flores | 25 | L | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0.0 | 1 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2016- 7- 206-CHA | premium | premium | premium | MLB | 2020-2021 | 2014-2025 | 2021 |
| Totals: | 90 | 72 | 4.00 | 718 | 162 | 3 | 1 | 159 | 556 | 50 | 1417.0 | 1234 | 672 | 629 | 152 | 608 | 1225 | 66 | 4 | 85 | 1.30 | 7.84 | 0.97 | 3.86 | 7.78 | 4.27 | 2.01 | premium | premium | premium |