| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 35 | Brandon Crawford | 34 | SS | L | 120 | 138 | 483 | 79 | 144 | 30 | 3 | 24 | 90 | 11 | 3 | 56 | 105 | 5 | 0 | 5 | 6 | 8 | 252 | 549 | 57 | 87 | .298 | .373 | .522 | .895 | .356 | .224 | .334 | 10.20 | 19.13 | 1.88 | 20.13 | 2008- 4- 117-SFN | premium | premium | premium | MLB | 2011-2024 | 2006-2024 | 2021 |
| 5 | Mike Yastrzemski | 30 | RF | L | 104 | 139 | 468 | 75 | 105 | 28 | 3 | 25 | 71 | 4 | 0 | 51 | 131 | 9 | 1 | 3 | 4 | 3 | 214 | 532 | 56 | 49 | .224 | .311 | .457 | .768 | .350 | .233 | .254 | 9.59 | 24.62 | 2.57 | 18.72 | 2013- 14- 429-BAL | premium | premium | premium | MLB | 2019-2025 | 2010-2025 | 2021 |
| 28 | Buster Posey | 34 | C | R | 120 | 113 | 395 | 68 | 120 | 23 | 0 | 18 | 56 | 0 | 0 | 56 | 87 | 1 | 0 | 2 | 5 | 15 | 197 | 454 | 41 | 79 | .304 | .390 | .499 | .889 | .337 | .195 | .349 | 12.33 | 19.16 | 1.55 | 21.94 | 2008- 1- 5-SFN | premium | premium | premium | MLB | 2009-2021 | 2006-2021 | 2021 |
| 41 | Wilmer Flores | 29 | 3B-1B | R | 107 | 139 | 389 | 57 | 102 | 16 | 1 | 18 | 53 | 1 | 0 | 41 | 56 | 3 | 0 | 3 | 0 | 11 | 174 | 436 | 35 | 67 | .262 | .335 | .447 | .782 | .293 | .185 | .264 | 9.40 | 12.84 | 1.37 | 21.61 | 2007- UDFA -NYN | premium | premium | premium | MLB | 2013-2025 | 2008-2025 | 2021 |
| 31 | LaMonte Wade | 27 | RF-LF | L | 110 | 109 | 336 | 52 | 85 | 17 | 3 | 18 | 56 | 6 | 1 | 33 | 89 | 5 | 4 | 3 | 1 | 3 | 162 | 381 | 38 | 47 | .253 | .326 | .482 | .808 | .342 | .229 | .289 | 8.66 | 23.36 | 2.70 | 18.67 | 2015- 9- 260-MIN | premium | premium | premium | MLB | 2019-2025 | 2013-2025 | 2021 |
| 9 | Brandon Belt | 33 | 1B | L | 129 | 97 | 325 | 65 | 89 | 14 | 2 | 29 | 59 | 3 | 2 | 48 | 103 | 7 | 0 | 1 | 3 | 9 | 194 | 381 | 45 | 44 | .274 | .378 | .597 | .975 | .474 | .323 | .309 | 12.60 | 27.03 | 2.15 | 11.21 | 2009- 5- 147-SFN | premium | premium | premium | MLB | 2011-2023 | 2008-2023 | 2021 |
| 7 | Donovan Solano | 33 | 2B | R | 103 | 101 | 307 | 35 | 86 | 17 | 0 | 7 | 31 | 2 | 0 | 25 | 58 | 7 | 1 | 4 | 2 | 8 | 124 | 344 | 24 | 62 | .280 | .344 | .404 | .748 | .212 | .124 | .321 | 7.27 | 16.86 | 2.32 | 43.86 | 2005- UDFA -SLN | premium | premium | premium | MLB | 2012-2025 | 2005-2025 | 2021 |
| 12 | Alex Dickerson | 31 | LF | L | 100 | 111 | 283 | 37 | 66 | 10 | 2 | 13 | 38 | 1 | 0 | 23 | 76 | 6 | 0 | 0 | 1 | 7 | 119 | 312 | 25 | 41 | .233 | .304 | .420 | .724 | .272 | .187 | .273 | 7.37 | 24.36 | 3.30 | 21.77 | 2011- 3- 91-PIT | premium | premium | premium | MLB | 2015-2022 | 2009-2025 | 2021 |
| 13 | Austin Slater | 28 | CF | R | 104 | 129 | 274 | 39 | 66 | 12 | 1 | 12 | 32 | 15 | 2 | 28 | 84 | 4 | 0 | 0 | 2 | 7 | 116 | 306 | 25 | 41 | .241 | .320 | .423 | .743 | .332 | .182 | .303 | 9.15 | 27.45 | 3.00 | 22.83 | 2014- 8- 238-SFN | premium | premium | premium | MLB | 2017-2025 | 2012-2025 | 2021 |
| 6 | Steven Duggar | 27 | CF | L | 105 | 107 | 268 | 45 | 69 | 14 | 5 | 8 | 35 | 7 | 0 | 27 | 88 | 2 | 0 | 0 | 3 | 4 | 117 | 297 | 27 | 42 | .257 | .330 | .437 | .767 | .306 | .180 | .355 | 9.09 | 29.63 | 3.26 | 33.50 | 2015- 6- 186-SFN | premium | premium | premium | MLB | 2018-2022 | 2013-2023 | 2021 |
| 33 | Darin Ruf | 34 | 1B-LF | R | 122 | 117 | 262 | 41 | 71 | 13 | 2 | 16 | 43 | 2 | 0 | 46 | 87 | 3 | 0 | 1 | 2 | 8 | 136 | 312 | 31 | 40 | .271 | .385 | .519 | .904 | .431 | .248 | .344 | 14.74 | 27.88 | 1.89 | 16.38 | 2009- 20- 617-PHI | premium | premium | premium | MLB | 2012-2023 | 2006-2023 | 2021 |
| 10 | Evan Longoria | 35 | 3B | R | 112 | 81 | 253 | 45 | 66 | 17 | 0 | 13 | 46 | 1 | 1 | 35 | 68 | 1 | 0 | 2 | 4 | 9 | 122 | 291 | 30 | 36 | .261 | .351 | .482 | .833 | .360 | .221 | .305 | 12.03 | 23.37 | 1.94 | 19.46 | 2006- 1- 3-TBA | premium | premium | premium | MLB | 2008-2023 | 2005-2023 | 2021 |
| 18 | Tommy La Stella | 32 | 2B | L | 97 | 76 | 220 | 26 | 55 | 11 | 1 | 7 | 27 | 0 | 0 | 18 | 26 | 1 | 0 | 1 | 1 | 4 | 89 | 240 | 19 | 36 | .250 | .308 | .405 | .713 | .236 | .155 | .255 | 7.50 | 10.83 | 1.44 | 31.43 | 2011- 8- 266-ATL | premium | premium | premium | MLB | 2014-2023 | 2008-2023 | 2021 |
| 2 | Curt Casali | 32 | C | R | 91 | 77 | 200 | 20 | 42 | 11 | 1 | 5 | 26 | 0 | 0 | 26 | 66 | 4 | 1 | 0 | 4 | 3 | 70 | 231 | 17 | 25 | .210 | .313 | .350 | .663 | .270 | .140 | .287 | 11.26 | 28.57 | 2.54 | 40.00 | 2011- 10- 317-DET | premium | premium | premium | MLB | 2014-2024 | 2008-2024 | 2021 |
| 17 | Kris Bryant | 29 | 3B-LF | R | 114 | 51 | 187 | 28 | 49 | 13 | 0 | 7 | 22 | 6 | 0 | 23 | 46 | 1 | 0 | 1 | 3 | 3 | 83 | 212 | 20 | 29 | .262 | .344 | .444 | .788 | .337 | .182 | .311 | 10.85 | 21.70 | 2.00 | 26.71 | 2013- 1- 2-CHN | premium | premium | premium | MLB | 2015-2025 | 2011-2025 | 2021 |
| 1 | Mauricio Dubon | 26 | CF-SS | R | 88* | 74 | 175 | 20 | 42 | 9 | 0 | 5 | 22 | 2 | 1 | 9 | 41 | 1 | 0 | 2 | 2 | 5 | 66 | 187 | 14 | 28 | .240 | .278 | .377 | .655 | .194 | .137 | .282 | 4.81 | 21.93 | 4.56 | 35.00 | 2013- 26- 773-BOS | premium | premium | premium | MLB | 2019-2025 | 2013-2025 | 2021 |
| 39 | Mike Tauchman | 30 | LF | L | 81* | 64 | 152 | 21 | 27 | 4 | 0 | 4 | 15 | 1 | 3 | 22 | 52 | 1 | 0 | 0 | 0 | 0 | 43 | 175 | 8 | 19 | .178 | .286 | .283 | .569 | .237 | .105 | .240 | 12.57 | 29.71 | 2.36 | 38.00 | 2013- 10- 289-COL | premium | premium | premium | MLB | 2017-2025 | 2010-2025 | 2021 |
| 39 | Thairo Estrada | 25 | SS-2B | R | 111* | 52 | 121 | 19 | 33 | 4 | 0 | 7 | 22 | 1 | 0 | 9 | 23 | 2 | 0 | 0 | 1 | 2 | 58 | 132 | 11 | 22 | .273 | .333 | .479 | .812 | .289 | .206 | .286 | 6.82 | 17.42 | 2.56 | 17.29 | 2012- UDFA -NYA | premium | premium | premium | MLB | 2019-2025 | 2013-2025 | 2021 |
| 32 | Jason Vosler | 27 | 3B | L | 41 | 73 | 12 | 13 | 4 | 0 | 3 | 9 | 2 | 0 | 7 | 21 | 1 | 0 | 1 | 1 | 5 | 26 | 82 | 7 | 6 | .178 | .256 | .356 | .612 | .301 | .178 | .200 | 8.54 | 25.61 | 3.00 | 24.33 | 2014- 16- 469-CHN | premium | premium | premium | MLB | 2021-2024 | 2012-2025 | 2021 | |
| 34 | Kevin Gausman | 30 | P | L | 31 | 54 | 6 | 10 | 0 | 0 | 0 | 4 | 0 | 0 | 2 | 31 | 0 | 5 | 1 | 0 | 0 | 10 | 62 | 0 | 10 | .185 | .211 | .185 | .396 | .037 | .000 | .417 | 3.23 | 50.00 | 15.50 | 0.00 | 2012- 1- 4-BAL | premium | premium | premium | MLB | 2013-2025 | 2011-2025 | 2021 | |
| 26 | Anthony DeSclafani | 31 | P | R | 33 | 51 | 2 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 4 | 33 | 0 | 7 | 0 | 0 | 0 | 3 | 62 | 1 | 1 | .039 | .109 | .059 | .168 | .098 | .020 | .111 | 6.45 | 53.23 | 8.25 | 0.00 | 2011- 6- 199-TOR | premium | premium | premium | MLB | 2014-2025 | 2009-2025 | 2021 | |
| 62 | Logan Webb | 24 | P | R | 26 | 46 | 7 | 6 | 2 | 1 | 1 | 7 | 0 | 0 | 2 | 21 | 0 | 5 | 0 | 0 | 1 | 13 | 53 | 4 | 2 | .130 | .167 | .283 | .450 | .196 | .153 | .208 | 3.77 | 39.62 | 10.50 | 46.00 | 2014- 4- 118-SFN | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 | |
| 57 | Alex Wood | 30 | P | R | 24 | 38 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 26 | 0 | 4 | 0 | 0 | 0 | 0 | 47 | 0 | 0 | .000 | .116 | .000 | .116 | .105 | .000 | .000 | 10.64 | 55.32 | 5.20 | 0.00 | 2012- 2- 85-ATL | premium | premium | premium | MLB | 2013-2024 | 2010-2024 | 2021 | |
| 47 | Johnny Cueto | 35 | P | R | 21 | 29 | 1 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 9 | 0 | 5 | 0 | 0 | 0 | 2 | 37 | 0 | 2 | .069 | .156 | .069 | .225 | .138 | .000 | .100 | 8.11 | 24.32 | 3.00 | 0.00 | 2004- UDFA -CIN | premium | premium | premium | MLB | 2008-2024 | 2005-2024 | 2021 | |
| 14 | Chadwick Tromp | 26 | C | R | 9 | 18 | 1 | 4 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 7 | 18 | 1 | 3 | .222 | .222 | .389 | .611 | .167 | .167 | .231 | 0.00 | 22.22 | 0.00 | 18.00 | 2013- UDFA -CIN | premium | premium | premium | MLB | 2020-2025 | 2013-2025 | 2021 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 73 | Sam Long | 25 | P | L | 11 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 0 | 0 | 0 | 1 | 11 | 0 | 1 | .100 | .100 | .100 | .200 | .000 | .000 | .167 | 0.00 | 36.36 | 0.00 | 0.00 | 2016- 18- 540-TBA | premium | premium | premium | MLB | 2021-2025 | 2014-2025 | 2021 | |
| 21 | Aaron Sanchez | 28 | P | R | 9 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 70.00 | 0.00 | 0.00 | 2010- 1- 34-TOR | premium | premium | premium | MLB | 2014-2022 | 2010-2024 | 2021 | |
| 49 | Jaylin Davis | 26 | LF-RF | R | 5 | 9 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2 | 9 | 1 | 0 | .111 | .111 | .222 | .333 | .111 | .111 | .125 | 0.00 | 11.11 | 0.00 | 0.00 | 2015- 24- 710-MIN | premium | premium | premium | MLB | 2019-2022 | 2013-2025 | 2021 | |
| 60 | Joey Bart | 24 | C | R | 2 | 6 | 1 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 6 | 0 | 2 | .333 | .333 | .333 | .666 | .000 | .000 | .500 | 0.00 | 33.33 | 0.00 | 0.00 | 2018- 1- 2-SFN | premium | premium | premium | MLB | 2020-2025 | 2016-2025 | 2021 | |
| 46 | Zack Littell | 25 | P | R | 60 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .250 | .250 | .250 | .500 | .000 | .000 | 1.000 | 0.00 | 75.00 | 0.00 | 0.00 | 2013- 11- 327-SEA | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 | |
| 16 | Scott Kazmir | 37 | P | L | 5 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2002- 1- 15-NYN | premium | premium | premium | MLB | 2004-2021 | 2002-2021 | 2021 | |
| 66 | Jarlin Garcia | 28 | P | L | 54 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2010- UDFA -MIA | premium | premium | premium | MLB | 2017-2022 | 2011-2022 | 2021 | |
| 48 | Jose Alvarez | 32 | P | L | 63 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .500 | .000 | .500 | 1.000 | .000 | .000 | 40.00 | 40.00 | 1.00 | 0.00 | 2005- UDFA -BOS | premium | premium | premium | MLB | 2013-2022 | 2007-2025 | 2021 | |
| 45 | Caleb Baragar | 27 | P | R | 24 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2016- 9- 275-SFN | premium | premium | premium | MLB | 2020-2021 | 2015-2025 | 2021 | |
| 67 | Sam Selman | 30 | P | R | 7 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2012- 2- 66-KCA | premium | premium | premium | MLB | 2019-2022 | 2010-2023 | 2021 | |
| 34 | Tyler Chatwood | 31 | P | R | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2008- 2- 74-ANA | premium | premium | premium | MLB | 2011-2021 | 2008-2024 | 2021 | |
| 37 | Matt Wisler | 28 | P | R | 18 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2011- 7- 233-SDN | premium | premium | premium | MLB | 2015-2022 | 2011-2023 | 2021 | |
| 59 | John Brebbia | 31 | P | L | 17 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2011- 30- 929-NYA | premium | premium | premium | MLB | 2017-2025 | 2009-2025 | 2021 | |
| 62 | Jose Quintana | 32 | P | R | 5 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | 1.000 | 1.000 | 1.000 | 2.000 | 1.000 | .000 | 1.000 | 50.00 | 0.00 | 0.00 | 0.00 | 2006- UDFA -NYN | premium | premium | premium | MLB | 2012-2025 | 2010-2025 | 2021 | |
| 65 | Skye Bolt | 27 | LF | B | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2015- 4- 128-OAK | premium | premium | premium | MLB | 2019-2022 | 2013-2024 | 2021 | |
| 65 | Jay Jackson | 33 | P | R | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2008- 9- 281-CHN | premium | premium | premium | MLB | 2015-2024 | 2006-2024 | 2021 | |
| Totals: | 2267 | 5462 | 804 | 1360 | 271 | 25 | 241 | 768 | 66 | 14 | 602 | 1461 | 64 | 36 | 30 | 45 | 117 | 2404 | 6194 | 537 | 823 | .249 | .329 | .440 | .769 | .311 | .191 | .295 | 9.72 | 23.59 | 2.43 | 22.66 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 62 | Jose Quintana | 32 | L | 0 | 0 | 4.66 | 5 | 0 | 0 | 0 | 5 | 0 | 0 | 9.2 | 8 | 5 | 5 | 3 | 6 | 12 | 2 | 1 | 0 | 1.45 | 7.45 | 2.79 | 5.59 | 11.17 | 4.66 | 2.00 | 2006- UDFA -NYN | premium | premium | premium | MLB | 2012-2025 | 2010-2025 | 2021 |
| 71 | Tyler Rogers | 30 | R | 7 | 1 | 2.22 | 80 | 0 | 0 | 0 | 80 | 18 | 13 | 81.0 | 74 | 23 | 20 | 5 | 13 | 55 | 0 | 0 | 5 | 1.07 | 8.22 | 0.56 | 1.44 | 6.11 | 2.56 | 4.23 | 2013- 10- 312-SFN | premium | premium | premium | MLB | 2019-2025 | 2012-2025 | 2021 |
| 60 | Wandy Peralta | 29 | L | 2 | 1 | 5.40 | 10 | 0 | 0 | 0 | 10 | 6 | 2 | 8.1 | 11 | 5 | 5 | 1 | 3 | 8 | 1 | 1 | 0 | 1.68 | 11.88 | 1.08 | 3.24 | 8.64 | 5.40 | 2.67 | 2009- UDFA -CIN | premium | premium | premium | MLB | 2016-2025 | 2010-2025 | 2021 |
| 67 | Sam Selman | 30 | L | 0 | 0 | 4.50 | 7 | 0 | 0 | 0 | 7 | 2 | 0 | 8.0 | 4 | 4 | 4 | 2 | 4 | 8 | 0 | 0 | 1 | 1.00 | 4.50 | 2.25 | 4.50 | 9.00 | 4.50 | 2.00 | 2012- 2- 66-KCA | premium | premium | premium | MLB | 2019-2022 | 2010-2023 | 2021 |
| 66 | Jarlin Garcia | 28 | L | 6 | 3 | 2.62 | 58 | 0 | 0 | 0 | 58 | 13 | 1 | 68.2 | 48 | 26 | 20 | 9 | 18 | 68 | 2 | 2 | 2 | 0.96 | 6.29 | 1.18 | 2.36 | 8.91 | 3.41 | 3.78 | 2010- UDFA -MIA | premium | premium | premium | MLB | 2017-2022 | 2011-2022 | 2021 |
| 48 | Jose Alvarez | 32 | L | 5 | 2 | 2.37 | 67 | 1 | 0 | 0 | 66 | 12 | 0 | 64.2 | 53 | 23 | 17 | 2 | 19 | 42 | 1 | 0 | 0 | 1.11 | 7.38 | 0.28 | 2.64 | 5.85 | 3.20 | 2.21 | 2005- UDFA -BOS | premium | premium | premium | MLB | 2013-2022 | 2007-2025 | 2021 |
| 46 | Zack Littell | 25 | R | 4 | 0 | 2.92 | 63 | 2 | 0 | 0 | 61 | 10 | 2 | 61.2 | 46 | 24 | 20 | 7 | 24 | 63 | 3 | 2 | 2 | 1.14 | 6.71 | 1.02 | 3.50 | 9.19 | 3.50 | 2.63 | 2013- 11- 327-SEA | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 63 | Nick Tropeano | 30 | R | 1 | 0 | 1.50 | 4 | 0 | 0 | 0 | 4 | 1 | 0 | 6.0 | 4 | 2 | 1 | 0 | 2 | 2 | 1 | 0 | 0 | 1.00 | 6.00 | 0.00 | 3.00 | 3.00 | 3.00 | 1.00 | 2011- 5- 160-HOU | premium | premium | premium | MLB | 2014-2021 | 2009-2025 | 2021 |
| 17 | Jake McGee | 34 | L | 3 | 2 | 2.72 | 62 | 0 | 0 | 0 | 62 | 42 | 31 | 59.2 | 44 | 25 | 18 | 7 | 10 | 58 | 0 | 0 | 2 | 0.91 | 6.64 | 1.06 | 1.51 | 8.75 | 3.77 | 5.80 | 2004- 5- 135-TBA | premium | premium | premium | MLB | 2010-2022 | 2004-2022 | 2021 |
| 52 | Dominic Leone | 29 | R | 4 | 5 | 1.51 | 57 | 4 | 0 | 0 | 53 | 11 | 2 | 53.2 | 37 | 15 | 9 | 2 | 22 | 50 | 2 | 0 | 1 | 1.10 | 6.20 | 0.34 | 3.69 | 8.39 | 2.52 | 2.27 | 2012- 16- 491-SEA | premium | premium | premium | MLB | 2014-2024 | 2010-2024 | 2021 |
| 73 | Sam Long | 25 | L | 2 | 1 | 5.53 | 12 | 5 | 0 | 0 | 7 | 2 | 0 | 40.2 | 37 | 27 | 25 | 5 | 15 | 38 | 5 | 0 | 3 | 1.28 | 8.19 | 1.11 | 3.32 | 8.41 | 5.98 | 2.53 | 2016- 18- 540-TBA | premium | premium | premium | MLB | 2021-2025 | 2014-2025 | 2021 |
| 34 | Tyler Chatwood | 31 | R | 0 | 1 | 6.75 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 4.0 | 6 | 5 | 3 | 1 | 1 | 6 | 0 | 0 | 1 | 1.75 | 13.50 | 2.25 | 2.25 | 13.50 | 11.25 | 6.00 | 2008- 2- 74-ANA | premium | premium | premium | MLB | 2011-2021 | 2008-2024 | 2021 |
| 54 | Reyes Moronta | 28 | R | 0 | 0 | 2.25 | 4 | 0 | 0 | 0 | 4 | 0 | 0 | 4.0 | 1 | 1 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 0.25 | 2.25 | 2.25 | 0.00 | 4.50 | 2.25 | 0.00 | 2010- UDFA -SFN | premium | premium | premium | MLB | 2017-2023 | 2011-2024 | 2021 |
| 21 | Aaron Sanchez | 28 | R | 1 | 1 | 3.06 | 9 | 7 | 0 | 0 | 2 | 1 | 0 | 35.1 | 32 | 12 | 12 | 2 | 15 | 26 | 0 | 1 | 4 | 1.33 | 8.15 | 0.51 | 3.82 | 6.62 | 3.06 | 1.73 | 2010- 1- 34-TOR | premium | premium | premium | MLB | 2014-2022 | 2010-2024 | 2021 |
| 75 | Camilo Doval | 23 | R | 5 | 1 | 3.00 | 29 | 0 | 0 | 0 | 29 | 9 | 3 | 27.0 | 19 | 10 | 9 | 4 | 9 | 37 | 2 | 0 | 1 | 1.04 | 6.33 | 1.33 | 3.00 | 12.33 | 3.33 | 4.11 | 2015- UDFA -SFN | premium | premium | premium | MLB | 2021-2025 | 2016-2025 | 2021 |
| 56 | Tony Watson | 36 | L | 4 | 1 | 2.96 | 26 | 0 | 0 | 0 | 26 | 0 | 0 | 24.1 | 15 | 8 | 8 | 1 | 4 | 19 | 0 | 0 | 0 | 0.78 | 5.55 | 0.37 | 1.48 | 7.03 | 2.96 | 4.75 | 2007- 9- 278-PIT | premium | premium | premium | MLB | 2011-2021 | 2004-2021 | 2021 |
| 45 | Caleb Baragar | 27 | L | 2 | 1 | 1.57 | 25 | 0 | 0 | 0 | 25 | 5 | 2 | 23.0 | 19 | 7 | 4 | 1 | 12 | 16 | 0 | 0 | 3 | 1.35 | 7.43 | 0.39 | 4.70 | 6.26 | 2.74 | 1.33 | 2016- 9- 275-SFN | premium | premium | premium | MLB | 2020-2021 | 2015-2025 | 2021 |
| 65 | Jay Jackson | 33 | R | 2 | 1 | 3.74 | 23 | 1 | 0 | 0 | 22 | 4 | 0 | 21.2 | 15 | 9 | 9 | 3 | 12 | 28 | 0 | 0 | 0 | 1.25 | 6.23 | 1.25 | 4.98 | 11.63 | 3.74 | 2.33 | 2008- 9- 281-CHN | premium | premium | premium | MLB | 2015-2024 | 2006-2024 | 2021 |
| 78 | Gregory Santos | 21 | R | 0 | 2 | 22.50 | 3 | 0 | 0 | 0 | 3 | 1 | 0 | 2.0 | 5 | 6 | 5 | 3 | 2 | 3 | 0 | 0 | 0 | 3.50 | 22.50 | 13.50 | 9.00 | 13.50 | 27.00 | 1.50 | 2015- UDFA -BOS | premium | premium | premium | MLB | 2021-2025 | 2016-2025 | 2021 |
| 34 | Kevin Gausman | 30 | R | 14 | 6 | 2.81 | 33 | 33 | 0 | 0 | 0 | 0 | 0 | 192.0 | 150 | 66 | 60 | 20 | 50 | 227 | 7 | 0 | 4 | 1.04 | 7.03 | 0.94 | 2.34 | 10.64 | 3.09 | 4.54 | 2012- 1- 4-BAL | premium | premium | premium | MLB | 2013-2025 | 2011-2025 | 2021 |
| 37 | Matt Wisler | 28 | R | 1 | 2 | 6.05 | 21 | 0 | 0 | 0 | 21 | 4 | 0 | 19.1 | 19 | 13 | 13 | 4 | 6 | 26 | 0 | 0 | 0 | 1.29 | 8.84 | 1.86 | 2.79 | 12.10 | 6.05 | 4.33 | 2011- 7- 233-SDN | premium | premium | premium | MLB | 2015-2022 | 2011-2023 | 2021 |
| 59 | John Brebbia | 31 | R | 0 | 1 | 5.89 | 18 | 0 | 0 | 0 | 18 | 6 | 0 | 18.1 | 25 | 13 | 12 | 4 | 4 | 22 | 0 | 0 | 2 | 1.58 | 12.27 | 1.96 | 1.96 | 10.80 | 6.38 | 5.50 | 2011- 30- 929-NYA | premium | premium | premium | MLB | 2017-2025 | 2009-2025 | 2021 |
| 26 | Anthony DeSclafani | 31 | R | 13 | 7 | 3.17 | 31 | 31 | 2 | 2 | 0 | 0 | 0 | 167.2 | 141 | 61 | 59 | 19 | 42 | 152 | 7 | 0 | 2 | 1.09 | 7.57 | 1.02 | 2.25 | 8.16 | 3.27 | 3.62 | 2011- 6- 199-TOR | premium | premium | premium | MLB | 2014-2025 | 2009-2025 | 2021 |
| 62 | Logan Webb | 24 | R | 11 | 3 | 3.03 | 27 | 26 | 0 | 0 | 1 | 0 | 0 | 148.1 | 128 | 53 | 50 | 9 | 36 | 158 | 2 | 0 | 8 | 1.11 | 7.77 | 0.55 | 2.18 | 9.59 | 3.22 | 4.39 | 2014- 4- 118-SFN | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 51 | Conner Menez | 26 | L | 1 | 0 | 3.86 | 8 | 1 | 0 | 0 | 7 | 0 | 0 | 14.0 | 16 | 10 | 6 | 2 | 3 | 15 | 0 | 0 | 0 | 1.36 | 10.29 | 1.29 | 1.93 | 9.64 | 6.43 | 5.00 | 2016- 14- 425-SFN | premium | premium | premium | MLB | 2019-2022 | 2016-2025 | 2021 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 57 | Alex Wood | 30 | L | 10 | 4 | 3.83 | 26 | 26 | 0 | 0 | 0 | 0 | 0 | 138.2 | 125 | 63 | 59 | 14 | 39 | 152 | 7 | 0 | 16 | 1.18 | 8.11 | 0.91 | 2.53 | 9.87 | 4.09 | 3.90 | 2012- 2- 85-ATL | premium | premium | premium | MLB | 2013-2024 | 2010-2024 | 2021 |
| 76 | Kervin Castro | 22 | R | 1 | 1 | 0.00 | 10 | 0 | 0 | 0 | 10 | 4 | 0 | 13.1 | 13 | 1 | 0 | 0 | 4 | 13 | 0 | 0 | 0 | 1.28 | 8.78 | 0.00 | 2.70 | 8.78 | 0.68 | 3.25 | 2015- UDFA -SFN | premium | premium | premium | MLB | 2021-2022 | 2016-2025 | 2021 |
| 47 | Johnny Cueto | 35 | R | 7 | 7 | 4.08 | 22 | 21 | 0 | 0 | 1 | 0 | 0 | 114.2 | 127 | 57 | 52 | 15 | 30 | 98 | 0 | 0 | 4 | 1.37 | 9.97 | 1.18 | 2.35 | 7.69 | 4.47 | 3.27 | 2004- UDFA -CIN | premium | premium | premium | MLB | 2008-2024 | 2005-2024 | 2021 |
| 16 | Scott Kazmir | 37 | L | 0 | 1 | 6.35 | 5 | 4 | 0 | 0 | 1 | 0 | 0 | 11.1 | 15 | 9 | 8 | 3 | 6 | 10 | 0 | 0 | 0 | 1.85 | 11.91 | 2.38 | 4.76 | 7.94 | 7.15 | 1.67 | 2002- 1- 15-NYN | premium | premium | premium | MLB | 2004-2021 | 2002-2021 | 2021 |
| 64 | James Sherfy | 29 | R | 1 | 0 | 4.22 | 10 | 0 | 0 | 0 | 10 | 4 | 0 | 10.2 | 9 | 5 | 5 | 2 | 4 | 9 | 1 | 0 | 1 | 1.22 | 7.59 | 1.69 | 3.37 | 7.59 | 4.22 | 2.25 | 2013- 10- 300-ARI | premium | premium | premium | MLB | 2017-2021 | 2011-2025 | 2021 |
| 33 | Darin Ruf | 34 | R | 0 | 0 | 18.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 3 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 | 27.00 | 0.00 | 0.00 | 0.00 | 18.00 | 0.00 | 2009- 20- 617-PHI | premium | premium | premium | MLB | 2012-2023 | 2006-2023 | 2021 |
| 39 | Mike Tauchman | 30 | L | 0 | 0 | 9.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 | 27.00 | 0.00 | 0.00 | 0.00 | 9.00 | 0.00 | 2013- 10- 289-COL | premium | premium | premium | MLB | 2017-2025 | 2010-2025 | 2021 |
| 38 | Tyler Beede | 28 | R | 0 | 0 | 27.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.0 | 2 | 3 | 3 | 0 | 0 | 2 | 1 | 0 | 1 | 2.00 | 18.00 | 0.00 | 0.00 | 18.00 | 27.00 | 0.00 | 2014- 1- 14-SFN | premium | premium | premium | MLB | 2018-2024 | 2012-2025 | 2021 |
| 13 | Austin Slater | 28 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0.1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.00 | 0.00 | 0.00 | 27.00 | 0.00 | 0.00 | 0.00 | 2014- 8- 238-SFN | premium | premium | premium | MLB | 2017-2025 | 2012-2025 | 2021 |
| Totals: | 107 | 55 | 3.25 | 761 | 162 | 2 | 2 | 160 | 599 | 56 | 1455.0 | 1254 | 594 | 525 | 151 | 416 | 1425 | 44 | 7 | 63 | 1.15 | 7.76 | 0.93 | 2.57 | 8.81 | 3.67 | 3.43 | premium | premium | premium |