| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 2 | Jeter Downs | 22 | SS | R | 84 | 99 | 357 | 39 | 68 | 9 | 0 | 14 | 39 | 18 | 3 | 38 | 131 | 4 | 1 | 5 | 0 | 7 | 119 | 405 | 23 | 45 | .190 | .272 | .333 | .605 | .291 | .143 | .249 | 9.38 | 32.35 | 3.45 | 25.50 | 2017- 1- 32-CIN | premium | premium | premium | MLB | 2022-2023 | 2017-2025 | 2021 |
| 60 | Yairo Munoz | 26 | 3B | R | 105 | 88 | 351 | 45 | 108 | 16 | 4 | 8 | 36 | 18 | 5 | 17 | 53 | 2 | 1 | 3 | 0 | 6 | 156 | 374 | 28 | 80 | .308 | .340 | .444 | .784 | .222 | .136 | .341 | 4.55 | 14.17 | 3.12 | 43.88 | 2012- UDFA -OAK | premium | premium | premium | MLB | 2018-2022 | 2012-2025 | 2021 |
| 30 | Josh Ockimey | 25 | 1B | L | 105 | 98 | 293 | 35 | 66 | 11 | 0 | 15 | 45 | 0 | 0 | 62 | 117 | 1 | 0 | 4 | 0 | 3 | 122 | 360 | 26 | 40 | .225 | .358 | .416 | .774 | .403 | .191 | .309 | 17.22 | 32.50 | 1.89 | 19.53 | 2014- 5- 164-BOS | premium | premium | premium | AAA | 2014-2022 | 2021 | |
| 37 | Franchy Cordero | 26 | LF | L | 124 | 78 | 287 | 53 | 86 | 24 | 2 | 13 | 56 | 12 | 1 | 42 | 94 | 5 | 0 | 0 | 2 | 3 | 153 | 334 | 39 | 47 | .300 | .398 | .533 | .931 | .418 | .233 | .406 | 12.57 | 28.14 | 2.24 | 22.08 | 2011- UDFA -SDN | premium | premium | premium | MLB | 2017-2023 | 2012-2025 | 2021 |
| 24 | Jarren Duran | 24 | CF | L | 117 | 60 | 244 | 46 | 63 | 11 | 2 | 16 | 36 | 16 | 3 | 30 | 66 | 8 | 0 | 1 | 0 | 1 | 126 | 283 | 29 | 34 | .258 | .357 | .516 | .873 | .434 | .258 | .288 | 10.60 | 23.32 | 2.20 | 15.25 | 2018- 7- 220-BOS | premium | premium | premium | MLB | 2021-2025 | 2016-2025 | 2021 |
| 3 | Jonathan Arauz | 22 | 2B | B | 94 | 68 | 233 | 32 | 57 | 8 | 1 | 6 | 30 | 2 | 0 | 30 | 45 | 0 | 0 | 4 | 0 | 7 | 85 | 267 | 15 | 42 | .245 | .326 | .365 | .691 | .258 | .120 | .274 | 11.24 | 16.85 | 1.50 | 38.83 | 2014- UDFA -PHI | premium | premium | premium | MLB | 2020-2023 | 2015-2025 | 2021 |
| 61 | Jack Lopez | 28 | 2B-SS | R | 101 | 68 | 223 | 29 | 61 | 14 | 1 | 3 | 33 | 15 | 2 | 19 | 54 | 7 | 0 | 3 | 0 | 6 | 86 | 252 | 18 | 43 | .274 | .345 | .386 | .731 | .256 | .112 | .343 | 7.54 | 21.43 | 2.84 | 74.33 | 2011- 16- 486-KCA | premium | premium | premium | MLB | 2021-2024 | 2012-2025 | 2021 |
| 12 | Marcus Wilson | 24 | RF | R | 112 | 64 | 219 | 34 | 53 | 10 | 3 | 10 | 30 | 10 | 1 | 41 | 88 | 4 | 0 | 1 | 0 | 3 | 99 | 265 | 23 | 30 | .242 | .370 | .452 | .822 | .438 | .210 | .352 | 15.47 | 33.21 | 2.15 | 21.90 | 2014- 2- 69-ARI | premium | premium | premium | MLB | 2022-2022 | 2014-2023 | 2021 |
| 39 | Johan Mieses | 25 | RF-LF | R | 93 | 59 | 199 | 28 | 42 | 9 | 1 | 8 | 26 | 3 | 1 | 22 | 64 | 6 | 0 | 3 | 0 | 3 | 77 | 230 | 18 | 24 | .211 | .304 | .387 | .691 | .296 | .176 | .262 | 9.57 | 27.83 | 2.91 | 24.88 | 2013- UDFA -LAN | premium | premium | premium | AAA | 2013-2024 | 2021 | |
| 7 | Connor Wong | 25 | C | R | 98 | 50 | 199 | 22 | 51 | 13 | 0 | 8 | 26 | 7 | 1 | 9 | 58 | 0 | 0 | 0 | 0 | 2 | 88 | 208 | 21 | 30 | .256 | .288 | .442 | .730 | .261 | .186 | .323 | 4.33 | 27.88 | 6.44 | 24.88 | 2017- 3- 100-LAN | premium | premium | premium | MLB | 2021-2025 | 2015-2025 | 2021 |
| 35 | Tate Matheny | 27 | CF | R | 95 | 62 | 182 | 27 | 41 | 15 | 1 | 5 | 28 | 4 | 1 | 20 | 74 | 0 | 0 | 0 | 0 | 2 | 73 | 202 | 21 | 20 | .225 | .302 | .401 | .703 | .302 | .176 | .350 | 9.90 | 36.63 | 3.70 | 36.40 | 2015- 4- 111-BOS | premium | premium | premium | AAA | 2013-2021 | 2021 | |
| 18 | Chris Herrmann | 33 | C | L | 101 | 48 | 153 | 26 | 34 | 9 | 1 | 7 | 20 | 0 | 0 | 22 | 56 | 3 | 0 | 2 | 1 | 1 | 66 | 180 | 17 | 17 | .222 | .328 | .431 | .759 | .353 | .209 | .293 | 12.22 | 31.11 | 2.55 | 21.86 | 2009- 6- 192-MIN | premium | premium | premium | MLB | 2012-2019 | 2009-2023 | 2021 |
| 13 | Chad De La Guerra | 28 | 3B | L | 92 | 49 | 152 | 22 | 30 | 11 | 1 | 3 | 13 | 6 | 0 | 23 | 57 | 2 | 0 | 0 | 0 | 1 | 52 | 177 | 15 | 15 | .197 | .311 | .342 | .653 | .336 | .145 | .293 | 12.99 | 32.20 | 2.48 | 50.67 | 2015- 17- 501-BOS | premium | premium | premium | AAA | 2012-2022 | 2021 | |
| 88 | Michael Gettys | 25 | RF-CF | R | 85 | 46 | 149 | 24 | 30 | 7 | 0 | 5 | 14 | 7 | 1 | 12 | 60 | 3 | 0 | 2 | 0 | 1 | 52 | 166 | 12 | 18 | .201 | .271 | .349 | .620 | .268 | .148 | .291 | 7.23 | 36.14 | 5.00 | 29.80 | 2014- 2- 51-SDN | premium | premium | premium | AAA | 2014-2022 | 2021 | |
| 65 | Joey Meneses | 29 | RF | R | 100 | 38 | 146 | 14 | 38 | 9 | 2 | 5 | 27 | 0 | 0 | 13 | 39 | 0 | 0 | 3 | 0 | 3 | 66 | 162 | 16 | 22 | .260 | .315 | .452 | .767 | .281 | .192 | .314 | 8.02 | 24.07 | 3.00 | 29.20 | 2011- UDFA -ATL | premium | premium | premium | MLB | 2022-2024 | 2011-2025 | 2021 |
| 53 | Jeremy Rivera | 26 | LF-2B | B | 99 | 45 | 137 | 23 | 37 | 7 | 0 | 2 | 12 | 3 | 0 | 15 | 28 | 2 | 2 | 0 | 0 | 1 | 50 | 156 | 9 | 28 | .270 | .351 | .365 | .716 | .226 | .095 | .327 | 9.62 | 17.95 | 1.87 | 68.50 | 2014- 17- 524-BOS | premium | premium | premium | AAA | 2014-2024 | 2021 | |
| 47 | Jett Bandy | 31 | C | R | 86* | 34 | 101 | 16 | 21 | 3 | 0 | 3 | 16 | 0 | 0 | 11 | 34 | 4 | 0 | 2 | 1 | 2 | 33 | 118 | 6 | 15 | .208 | .305 | .327 | .632 | .228 | .119 | .273 | 9.32 | 28.81 | 3.09 | 33.67 | 2011- 31- 945-ANA | premium | premium | premium | MLB | 2015-2018 | 2009-2021 | 2021 |
| 17 | Michael Chavis | 25 | 1B | R | 115 | 24 | 95 | 19 | 25 | 2 | 0 | 6 | 17 | 1 | 0 | 8 | 30 | 2 | 0 | 2 | 0 | 1 | 45 | 107 | 8 | 17 | .263 | .327 | .474 | .801 | .305 | .211 | .311 | 7.48 | 28.04 | 3.75 | 15.83 | 2014- 1- 26-BOS | premium | premium | premium | MLB | 2019-2023 | 2014-2025 | 2021 |
| 28 | Jhonny Pereda | 25 | C | R | 83* | 25 | 77 | 8 | 19 | 2 | 0 | 0 | 11 | 1 | 0 | 9 | 10 | 0 | 0 | 2 | 0 | 6 | 21 | 88 | 2 | 17 | .247 | .318 | .273 | .591 | .156 | .026 | .275 | 10.23 | 11.36 | 1.11 | 0.00 | 2013- UDFA -CHN | premium | premium | premium | MLB | 2024-2025 | 2015-2025 | 2021 |
| 12 | Delino DeShields | 28 | CF-LF | R | 101* | 18 | 62 | 10 | 13 | 4 | 1 | 1 | 4 | 5 | 1 | 13 | 24 | 1 | 0 | 0 | 0 | 1 | 22 | 76 | 6 | 7 | .210 | .355 | .355 | .710 | .419 | .145 | .324 | 17.11 | 31.58 | 1.85 | 62.00 | 2010- 1- 8-HOU | premium | premium | premium | MLB | 2015-2021 | 2010-2025 | 2021 |
| 32 | Taylor Motter | 31 | 3B | R | 14 | 45 | 5 | 10 | 2 | 0 | 0 | 6 | 0 | 0 | 7 | 13 | 0 | 0 | 0 | 0 | 0 | 12 | 52 | 2 | 8 | .222 | .327 | .267 | .594 | .200 | .045 | .313 | 13.46 | 25.00 | 1.86 | 0.00 | 2011- 17- 540-TBA | premium | premium | premium | MLB | 2016-2023 | 2009-2024 | 2021 | |
| 15 | Ryan Fitzgerald | 27 | 3B-2B | L | 13 | 42 | 9 | 11 | 2 | 1 | 3 | 9 | 0 | 1 | 4 | 13 | 1 | 0 | 0 | 0 | 0 | 24 | 47 | 6 | 5 | .262 | .340 | .571 | .911 | .381 | .309 | .308 | 8.51 | 27.66 | 3.25 | 14.00 | 2018- UDFA -BOS | premium | premium | premium | MLB | 2025-2025 | 2013-2025 | 2021 | |
| 22 | Danny Santana | 30 | 1B-LF | B | 12 | 40 | 8 | 12 | 5 | 0 | 2 | 4 | 2 | 0 | 7 | 9 | 0 | 0 | 0 | 1 | 0 | 23 | 47 | 7 | 5 | .300 | .404 | .575 | .979 | .500 | .275 | .345 | 14.89 | 19.15 | 1.29 | 20.00 | 2007- UDFA -MIN | premium | premium | premium | MLB | 2014-2021 | 2009-2025 | 2021 | |
| 25 | Cesar Puello | 30 | RF | R | 91 | 15 | 38 | 6 | 6 | 1 | 0 | 0 | 7 | 6 | 1 | 8 | 8 | 6 | 0 | 2 | 0 | 1 | 7 | 54 | 1 | 5 | .158 | .370 | .184 | .554 | .368 | .026 | .188 | 14.81 | 14.81 | 1.00 | 0.00 | 2007- UDFA -NYN | premium | premium | premium | MLB | 2017-2020 | 2008-2021 | 2021 |
| 5 | Grant Williams | 25 | 2B | L | 11 | 34 | 5 | 9 | 0 | 1 | 0 | 4 | 2 | 1 | 3 | 7 | 0 | 2 | 0 | 0 | 0 | 11 | 39 | 1 | 8 | .265 | .324 | .324 | .648 | .176 | .059 | .333 | 7.69 | 17.95 | 2.33 | 0.00 | 2018- 10- 310-BOS | premium | premium | premium | AAA | 2015-2022 | 2021 | ||
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 36 | Triston Casas | 21 | 1B | L | 9 | 33 | 6 | 8 | 3 | 1 | 1 | 7 | 1 | 0 | 8 | 8 | 0 | 0 | 1 | 0 | 1 | 16 | 42 | 5 | 3 | .242 | .381 | .485 | .866 | .515 | .243 | .280 | 19.05 | 19.05 | 1.00 | 33.00 | 2018- 1- 26-BOS | premium | premium | premium | MLB | 2022-2025 | 2018-2025 | 2021 | |
| - | Christian Arroyo | 26 | 2B | R | 11 | 33 | 4 | 3 | 1 | 0 | 0 | 2 | 1 | 0 | 2 | 12 | 2 | 0 | 1 | 0 | 0 | 4 | 38 | 1 | 2 | .091 | .184 | .121 | .305 | .121 | .030 | .136 | 5.26 | 31.58 | 6.00 | 0.00 | 2013- 1- 25-SFN | premium | premium | premium | MLB | 2017-2023 | 2013-2025 | 2021 | |
| 59 | Ronaldo Hernandez | 23 | C | R | 7 | 27 | 1 | 9 | 3 | 0 | 0 | 5 | 0 | 0 | 1 | 7 | 2 | 0 | 0 | 0 | 0 | 12 | 30 | 3 | 6 | .333 | .400 | .444 | .844 | .148 | .111 | .450 | 3.33 | 23.33 | 7.00 | 0.00 | 2014- UDFA -TBA | premium | premium | premium | AAA | 2015-2025 | 2021 | ||
| - | Marwin Gonzalez | 32 | 2B-1B | B | 2 | 6 | 1 | 2 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 5 | 7 | 1 | 1 | .333 | .429 | .833 | 1.262 | .667 | .500 | .250 | 14.29 | 14.29 | 1.00 | 6.00 | 2005- UDFA -CHN | premium | premium | premium | MLB | 2012-2022 | 2006-2024 | 2021 | |
| 5 | Enrique Hernandez | 29 | CF | R | 2 | 6 | 3 | 2 | 0 | 0 | 2 | 5 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 8 | 7 | 2 | 0 | .333 | .429 | 1.333 | 1.762 | 1.000 | 1.000 | .000 | 0.00 | 28.57 | 0.00 | 3.00 | 2009- 6- 191-HOU | premium | premium | premium | MLB | 2014-2025 | 2009-2025 | 2021 | |
| - | Ricardo Cubillan | 23 | LF | B | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2014- UDFA -BOS | premium | premium | premium | AAA | 2016-2022 | 2021 | ||
| Totals: | 1218 | 4164 | 600 | 1015 | 211 | 23 | 147 | 569 | 140 | 23 | 497 | 1263 | 66 | 6 | 41 | 5 | 62 | 1713 | 4774 | 381 | 634 | .244 | .331 | .411 | .742 | .315 | .168 | .311 | 10.41 | 26.46 | 2.54 | 28.33 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 19 | Daniel Gossett | 28 | R | 7 | 5 | 4.22 | 20 | 18 | 0 | 0 | 2 | 0 | 0 | 98.0 | 94 | 54 | 46 | 14 | 46 | 81 | 4 | 0 | 0 | 1.43 | 8.63 | 1.29 | 4.22 | 7.44 | 4.96 | 1.76 | 2014- 2- 65-OAK | premium | premium | premium | MLB | 2017-2018 | 2012-2022 | 2021 |
| - | Chris Sale | 32 | L | 1 | 0 | 0.93 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 9.2 | 7 | 1 | 1 | 0 | 4 | 15 | 0 | 0 | 0 | 1.14 | 6.52 | 0.00 | 3.72 | 13.97 | 0.93 | 3.75 | 2010- 1- 13-CHA | premium | premium | premium | MLB | 2010-2025 | 2008-2025 | 2021 |
| 32 | Stephen Gonsalves | 26 | L | 5 | 4 | 4.68 | 22 | 10 | 0 | 0 | 12 | 2 | 1 | 73.0 | 65 | 41 | 38 | 13 | 52 | 103 | 3 | 1 | 6 | 1.60 | 8.01 | 1.60 | 6.41 | 12.70 | 5.05 | 1.98 | 2013- 4- 110-MIN | premium | premium | premium | MLB | 2018-2021 | 2013-2025 | 2021 |
| 44 | Brandon Workman | 32 | R | 0 | 0 | 1.29 | 7 | 0 | 0 | 0 | 7 | 2 | 1 | 7.0 | 3 | 1 | 1 | 0 | 4 | 10 | 0 | 0 | 0 | 1.00 | 3.86 | 0.00 | 5.14 | 12.86 | 1.29 | 2.50 | 2010- 2- 57-BOS | premium | premium | premium | MLB | 2013-2021 | 2008-2021 | 2021 |
| 20 | John Schreiber | 27 | R | 3 | 3 | 2.71 | 33 | 8 | 0 | 0 | 25 | 6 | 1 | 66.1 | 61 | 23 | 20 | 3 | 26 | 65 | 2 | 0 | 1 | 1.31 | 8.28 | 0.41 | 3.53 | 8.82 | 3.12 | 2.50 | 2016- 15- 445-DET | premium | premium | premium | MLB | 2019-2025 | 2015-2025 | 2021 |
| 75 | Yacksel Rios | 28 | R | 0 | 0 | 7.50 | 5 | 0 | 0 | 0 | 5 | 2 | 1 | 6.0 | 10 | 5 | 5 | 0 | 3 | 8 | 3 | 0 | 0 | 2.17 | 15.00 | 0.00 | 4.50 | 12.00 | 7.50 | 2.67 | 2011- 12- 391-PHI | premium | premium | premium | MLB | 2017-2023 | 2011-2025 | 2021 |
| 23 | Connor Seabold | 25 | R | 4 | 3 | 3.50 | 11 | 11 | 0 | 0 | 0 | 0 | 0 | 54.0 | 43 | 24 | 21 | 6 | 19 | 52 | 2 | 0 | 6 | 1.15 | 7.17 | 1.00 | 3.17 | 8.67 | 4.00 | 2.74 | 2017- 3- 83-PHI | premium | premium | premium | MLB | 2021-2025 | 2015-2025 | 2021 |
| 37 | Enmanuel De Jesus | 24 | L | 0 | 1 | 3.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 5.0 | 4 | 2 | 2 | 2 | 1 | 3 | 0 | 0 | 0 | 1.00 | 7.20 | 3.60 | 1.80 | 5.40 | 3.60 | 3.00 | 2013- UDFA -BOS | premium | premium | premium | MLB | 2023-2023 | 2014-2023 | 2021 |
| 31 | Kutter Crawford | 25 | R | 3 | 4 | 5.21 | 10 | 9 | 0 | 0 | 1 | 0 | 0 | 48.1 | 49 | 29 | 28 | 5 | 15 | 67 | 1 | 2 | 3 | 1.32 | 9.12 | 0.93 | 2.79 | 12.48 | 5.40 | 4.47 | 2017- 16- 491-BOS | premium | premium | premium | MLB | 2021-2024 | 2015-2024 | 2021 |
| 85 | Kaleb Ort | 29 | R | 1 | 3 | 2.98 | 42 | 0 | 0 | 0 | 42 | 35 | 19 | 45.1 | 40 | 19 | 15 | 4 | 20 | 62 | 1 | 0 | 5 | 1.32 | 7.94 | 0.79 | 3.97 | 12.31 | 3.77 | 3.10 | 2016- UDFA -ARI | premium | premium | premium | MLB | 2021-2025 | 2016-2025 | 2021 |
| 21 | Marcus Walden | 32 | R | 5 | 3 | 4.01 | 27 | 3 | 0 | 0 | 24 | 5 | 0 | 42.2 | 46 | 23 | 19 | 5 | 19 | 40 | 1 | 0 | 2 | 1.52 | 9.70 | 1.05 | 4.01 | 8.44 | 4.85 | 2.11 | 2007- 9- 295-TOR | premium | premium | premium | MLB | 2018-2020 | 2007-2023 | 2021 |
| 65 | Ryan Brasier | 33 | R | 1 | 0 | 19.29 | 5 | 0 | 0 | 0 | 5 | 0 | 0 | 4.2 | 9 | 10 | 10 | 1 | 3 | 3 | 0 | 0 | 0 | 2.57 | 17.36 | 1.93 | 5.79 | 5.79 | 19.29 | 1.00 | 2007- 6- 208-ANA | premium | premium | premium | MLB | 2013-2025 | 2007-2025 | 2021 |
| 35 | Matt Andriese | 31 | R | 0 | 0 | 0.00 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 4.0 | 3 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0.75 | 6.75 | 0.00 | 0.00 | 9.00 | 0.00 | 0.00 | 2011- 3- 112-SDN | premium | premium | premium | MLB | 2015-2024 | 2009-2024 | 2021 |
| 39 | Brandon Brennan | 29 | R | 1 | 2 | 5.97 | 32 | 0 | 0 | 0 | 32 | 6 | 1 | 37.2 | 44 | 28 | 25 | 3 | 15 | 37 | 0 | 0 | 5 | 1.57 | 10.51 | 0.72 | 3.58 | 8.84 | 6.69 | 2.47 | 2012- 4- 141-CHA | premium | premium | premium | MLB | 2019-2021 | 2011-2025 | 2021 |
| 22 | Matt Hall | 27 | L | 2 | 2 | 7.36 | 28 | 0 | 0 | 0 | 28 | 10 | 1 | 36.2 | 50 | 34 | 30 | 4 | 26 | 37 | 6 | 0 | 2 | 2.07 | 12.27 | 0.98 | 6.38 | 9.08 | 8.35 | 1.42 | 2015- 6- 190-DET | premium | premium | premium | MLB | 2018-2020 | 2013-2024 | 2021 |
| 40 | Kevin McCarthy | 29 | R | 1 | 2 | 7.13 | 28 | 2 | 0 | 0 | 26 | 7 | 1 | 35.1 | 54 | 31 | 28 | 5 | 6 | 35 | 1 | 0 | 4 | 1.70 | 13.75 | 1.27 | 1.53 | 8.92 | 7.90 | 5.83 | 2013- 16- 474-KCA | premium | premium | premium | MLB | 2016-2020 | 2011-2024 | 2021 |
| 5 | Ryan Weber | 30 | R | 2 | 2 | 4.63 | 7 | 6 | 0 | 0 | 1 | 0 | 0 | 35.0 | 35 | 22 | 18 | 5 | 10 | 33 | 1 | 0 | 3 | 1.29 | 9.00 | 1.29 | 2.57 | 8.49 | 5.66 | 3.30 | 2009- 22- 658-ATL | premium | premium | premium | MLB | 2015-2023 | 2009-2023 | 2021 |
| 25 | Austin Brice | 29 | R | 3 | 0 | 3.27 | 26 | 2 | 0 | 0 | 24 | 10 | 2 | 33.0 | 25 | 12 | 12 | 4 | 14 | 34 | 1 | 0 | 9 | 1.18 | 6.82 | 1.09 | 3.82 | 9.27 | 3.27 | 2.43 | 2010- 9- 287-MIA | premium | premium | premium | MLB | 2016-2022 | 2010-2024 | 2021 |
| 31 | Geoff Hartlieb | 27 | R | 1 | 0 | 0.00 | 4 | 0 | 0 | 0 | 4 | 1 | 0 | 3.2 | 0 | 1 | 0 | 0 | 4 | 2 | 0 | 0 | 2 | 1.09 | 0.00 | 0.00 | 9.82 | 4.91 | 2.45 | 0.50 | 2016- 29- 885-PIT | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 15 | Durbin Feltman | 24 | R | 2 | 1 | 2.59 | 17 | 0 | 0 | 0 | 17 | 7 | 1 | 24.1 | 18 | 7 | 7 | 3 | 4 | 25 | 1 | 0 | 0 | 0.90 | 6.66 | 1.11 | 1.48 | 9.25 | 2.59 | 6.25 | 2018- 3- 100-BOS | premium | premium | premium | AAA | 2016-2025 | 2021 | |
| 36 | Seth Blair | 32 | R | 3 | 1 | 3.80 | 17 | 1 | 0 | 0 | 16 | 7 | 0 | 23.2 | 17 | 11 | 10 | 1 | 11 | 30 | 3 | 1 | 12 | 1.18 | 6.46 | 0.38 | 4.18 | 11.41 | 4.18 | 2.73 | 2010- 1- 46-SLN | premium | premium | premium | AAA | 2008-2023 | 2021 | |
| 89 | Tanner Houck | 25 | R | 0 | 2 | 5.14 | 6 | 6 | 0 | 0 | 0 | 0 | 0 | 21.0 | 19 | 13 | 12 | 1 | 7 | 26 | 0 | 0 | 3 | 1.24 | 8.14 | 0.43 | 3.00 | 11.14 | 5.57 | 3.71 | 2017- 1- 24-BOS | premium | premium | premium | MLB | 2020-2025 | 2015-2025 | 2021 |
| 60 | Michael Feliz | 28 | R | 1 | 0 | 0.00 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 2.0 | 1 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0.50 | 4.50 | 0.00 | 0.00 | 18.00 | 0.00 | 0.00 | 2010- UDFA -HOU | premium | premium | premium | MLB | 2015-2022 | 2010-2025 | 2021 |
| 61 | Brad Peacock | 33 | R | 0 | 0 | 13.50 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 2.0 | 4 | 3 | 3 | 2 | 2 | 3 | 0 | 0 | 0 | 3.00 | 18.00 | 9.00 | 9.00 | 13.50 | 13.50 | 1.50 | 2006- 41-1231-WAS | premium | premium | premium | MLB | 2011-2021 | 2007-2022 | 2021 |
| 17 | Zack Kelly | 26 | R | 1 | 0 | 2.89 | 15 | 0 | 0 | 0 | 15 | 2 | 1 | 18.2 | 13 | 6 | 6 | 1 | 5 | 29 | 3 | 1 | 1 | 0.96 | 6.27 | 0.48 | 2.41 | 13.98 | 2.89 | 5.80 | 2017- UDFA -OAK | premium | premium | premium | MLB | 2022-2025 | 2016-2025 | 2021 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 62 | Colten Brewer | 28 | R | 1 | 1 | 4.00 | 11 | 0 | 0 | 0 | 11 | 2 | 1 | 18.0 | 15 | 8 | 8 | 2 | 9 | 18 | 2 | 0 | 0 | 1.33 | 7.50 | 1.00 | 4.50 | 9.00 | 4.00 | 2.00 | 2011- 4- 122-PIT | premium | premium | premium | MLB | 2018-2024 | 2012-2025 | 2021 |
| 5 | Phillips Valdez | 29 | R | 1 | 0 | 3.94 | 17 | 0 | 0 | 0 | 17 | 5 | 1 | 16.0 | 13 | 7 | 7 | 2 | 14 | 20 | 1 | 0 | 0 | 1.69 | 7.31 | 1.13 | 7.88 | 11.25 | 3.94 | 1.43 | 2008- UDFA -CLE | premium | premium | premium | MLB | 2019-2022 | 2010-2025 | 2021 |
| 52 | Jose Adames | 28 | R | 2 | 0 | 6.32 | 16 | 0 | 0 | 0 | 16 | 5 | 0 | 15.2 | 19 | 15 | 11 | 2 | 12 | 19 | 2 | 1 | 3 | 1.98 | 10.91 | 1.15 | 6.89 | 10.91 | 8.62 | 1.58 | 2010- UDFA -MIA | premium | premium | premium | AAA | 2011-2025 | 2021 | |
| 68 | Caleb Simpson | 29 | R | 1 | 0 | 3.86 | 13 | 0 | 0 | 0 | 13 | 3 | 0 | 14.0 | 9 | 6 | 6 | 2 | 8 | 21 | 3 | 0 | 3 | 1.21 | 5.79 | 1.29 | 5.14 | 13.50 | 3.86 | 2.63 | 2013- 21- 642-SFN | premium | premium | premium | AAA | 2013-2023 | 2021 | |
| 36 | Bobby Poyner | 28 | L | 0 | 0 | 9.69 | 8 | 0 | 0 | 0 | 8 | 2 | 0 | 13.0 | 22 | 15 | 14 | 6 | 2 | 12 | 0 | 0 | 3 | 1.85 | 15.23 | 4.15 | 1.38 | 8.31 | 10.38 | 6.00 | 2015- 14- 411-BOS | premium | premium | premium | MLB | 2018-2019 | 2012-2021 | 2021 |
| 21 | Josh Winckowski | 23 | R | 1 | 1 | 2.25 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 12.0 | 5 | 3 | 3 | 1 | 3 | 13 | 0 | 0 | 1 | 0.67 | 3.75 | 0.75 | 2.25 | 9.75 | 2.25 | 4.33 | 2016- 15- 462-TOR | premium | premium | premium | MLB | 2022-2025 | 2016-2025 | 2021 |
| 55 | Raynel Espinal | 29 | R | 11 | 4 | 3.44 | 23 | 21 | 0 | 0 | 2 | 0 | 0 | 117.2 | 86 | 50 | 45 | 12 | 43 | 115 | 6 | 2 | 10 | 1.10 | 6.58 | 0.92 | 3.29 | 8.80 | 3.82 | 2.67 | 2012- UDFA -NYA | premium | premium | premium | MLB | 2021-2022 | 2013-2025 | 2021 |
| 21 | Alex Claudio | 29 | L | 0 | 0 | 6.17 | 8 | 2 | 0 | 0 | 6 | 1 | 1 | 11.2 | 15 | 9 | 8 | 0 | 3 | 13 | 0 | 1 | 0 | 1.54 | 11.57 | 0.00 | 2.31 | 10.03 | 6.94 | 4.33 | 2010- 27- 826-TEX | premium | premium | premium | MLB | 2014-2023 | 2010-2025 | 2021 |
| 31 | Matthew Kent | 28 | L | 1 | 0 | 5.40 | 3 | 2 | 0 | 0 | 1 | 0 | 0 | 11.2 | 9 | 7 | 7 | 1 | 4 | 9 | 1 | 0 | 2 | 1.11 | 6.94 | 0.77 | 3.09 | 6.94 | 5.40 | 2.25 | 2015- 13- 381-BOS | premium | premium | premium | AAA | 2013-2022 | 2021 | |
| 24 | Eduard Bazardo | 25 | R | 1 | 1 | 8.74 | 11 | 0 | 0 | 0 | 11 | 4 | 3 | 11.1 | 16 | 11 | 11 | 3 | 5 | 12 | 1 | 0 | 2 | 1.85 | 12.71 | 2.38 | 3.97 | 9.53 | 8.74 | 2.40 | 2014- UDFA -BOS | premium | premium | premium | MLB | 2021-2025 | 2015-2025 | 2021 |
| 38 | Kyle Hart | 28 | L | 6 | 9 | 4.22 | 23 | 20 | 1 | 0 | 3 | 0 | 0 | 106.2 | 100 | 58 | 50 | 19 | 47 | 90 | 2 | 3 | 8 | 1.38 | 8.44 | 1.60 | 3.97 | 7.59 | 4.89 | 1.91 | 2016- 19- 568-BOS | premium | premium | premium | MLB | 2020-2025 | 2012-2025 | 2021 |
| 53 | Zac Grotz | 28 | R | 1 | 0 | 9.58 | 8 | 1 | 0 | 0 | 7 | 1 | 0 | 10.1 | 17 | 11 | 11 | 3 | 4 | 7 | 0 | 0 | 2 | 2.03 | 14.81 | 2.61 | 3.48 | 6.10 | 9.58 | 1.75 | 2015- 28- 829-HOU | premium | premium | premium | MLB | 2019-2020 | 2013-2025 | 2021 |
| 54 | Martin Perez | 30 | L | 1 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.00 | 9.00 | 0.00 | 0.00 | 9.00 | 0.00 | 0.00 | 2007- UDFA -TEX | premium | premium | premium | MLB | 2012-2025 | 2008-2025 | 2021 |
| 39 | Hirokazu Sawamura | 33 | R | 0 | 0 | 0.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 9.00 | 0.00 | 0.00 | 2021- UDFA -BOS | premium | premium | premium | MLB | 2021-2022 | 2011-2025 | 2021 |
| - | Matt Barnes | 31 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0.00 | 0.00 | 0.00 | 0.00 | 9.00 | 0.00 | 0.00 | 2011- 1- 19-BOS | premium | premium | premium | MLB | 2014-2024 | 2009-2024 | 2021 |
| 35 | Tate Matheny | 27 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 | 9.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2015- 4- 111-BOS | premium | premium | premium | AAA | 2013-2021 | 2021 | |
| 53 | Darwinzon Hernandez | 24 | L | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1.00 | 0.00 | 0.00 | 9.00 | 9.00 | 0.00 | 1.00 | 2013- UDFA -BOS | premium | premium | premium | MLB | 2019-2022 | 2014-2025 | 2021 |
| Totals: | 74 | 54 | 4.40 | 520 | 128 | 1 | 0 | 127 | 392 | 36 | 1100.0 | 1042 | 600 | 538 | 135 | 471 | 1161 | 51 | 12 | 99 | 1.38 | 8.53 | 1.10 | 3.85 | 9.50 | 4.91 | 2.46 | premium | premium | premium |