| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 7 | Jose Tena | 20 | SS | L | 107 | 107 | 413 | 58 | 116 | 25 | 2 | 16 | 58 | 10 | 5 | 27 | 117 | 5 | 0 | 2 | 2 | 4 | 193 | 447 | 43 | 73 | .281 | .331 | .467 | .798 | .264 | .186 | .355 | 6.04 | 26.17 | 4.33 | 25.81 | 2017- UDFA -CLE | premium | premium | premium | MLB | 2023-2025 | 2018-2025 | 2021 |
| 6 | Joe Naranjo | 20 | 1B | L | 92 | 109 | 374 | 44 | 88 | 13 | 1 | 6 | 50 | 7 | 1 | 44 | 115 | 6 | 0 | 2 | 1 | 9 | 121 | 426 | 20 | 68 | .235 | .324 | .324 | .648 | .222 | .089 | .322 | 10.33 | 27.00 | 2.61 | 62.33 | 2019- 3- 101-CLE | premium | premium | premium | AA | 2019-2025 | 2021 | |
| 15 | Raynel Delgado | 21 | 2B-3B | L | 85 | 100 | 336 | 33 | 70 | 13 | 1 | 8 | 35 | 14 | 7 | 31 | 108 | 6 | 1 | 3 | 1 | 5 | 109 | 377 | 22 | 48 | .208 | .285 | .324 | .609 | .229 | .116 | .278 | 8.22 | 28.65 | 3.48 | 42.00 | 2018- 6- 193-CLE | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 4 | Brayan Rocchio | 20 | SS | B | 105 | 64 | 257 | 45 | 68 | 13 | 1 | 9 | 33 | 14 | 6 | 20 | 65 | 9 | 0 | 2 | 0 | 0 | 110 | 288 | 23 | 45 | .265 | .337 | .428 | .765 | .272 | .163 | .319 | 6.94 | 22.57 | 3.25 | 28.56 | 2017- UDFA -CLE | premium | premium | premium | MLB | 2023-2025 | 2018-2025 | 2021 |
| 17 | Aaron Bracho | 20 | 2B | L | 79 | 70 | 241 | 27 | 42 | 9 | 0 | 7 | 27 | 1 | 2 | 32 | 89 | 1 | 0 | 5 | 1 | 1 | 72 | 279 | 16 | 26 | .174 | .269 | .299 | .568 | .253 | .125 | .233 | 11.47 | 31.90 | 2.78 | 34.43 | 2017- UDFA -CLE | premium | premium | premium | AA | 2019-2025 | 2021 | |
| 31 | Victor Nova | 21 | 3B-LF | L | 92 | 75 | 241 | 38 | 50 | 9 | 3 | 5 | 32 | 10 | 4 | 37 | 77 | 3 | 0 | 2 | 0 | 4 | 80 | 283 | 17 | 33 | .207 | .318 | .332 | .650 | .303 | .125 | .280 | 13.07 | 27.21 | 2.08 | 48.20 | 2017- UDFA -SDN | premium | premium | premium | AAA | 2018-2024 | 2021 | |
| 16 | Will Brennan | 23 | CF | L | 112 | 62 | 238 | 42 | 69 | 22 | 1 | 4 | 30 | 13 | 4 | 25 | 43 | 5 | 0 | 1 | 0 | 3 | 105 | 269 | 27 | 42 | .290 | .368 | .441 | .809 | .294 | .151 | .339 | 9.29 | 15.99 | 1.72 | 59.50 | 2019- 8- 250-CLE | premium | premium | premium | MLB | 2022-2025 | 2017-2025 | 2021 |
| 37 | Quentin Holmes | 21 | CF-RF | R | 83 | 64 | 199 | 20 | 45 | 5 | 2 | 2 | 19 | 17 | 6 | 16 | 79 | 1 | 1 | 2 | 0 | 0 | 60 | 219 | 9 | 36 | .226 | .284 | .302 | .586 | .211 | .076 | .358 | 7.31 | 36.07 | 4.94 | 99.50 | 2017- 2- 64-CLE | premium | premium | premium | AA | 2017-2023 | 2021 | |
| 13 | George Valera | 20 | RF | L | 131 | 63 | 199 | 45 | 51 | 2 | 4 | 16 | 43 | 10 | 5 | 55 | 58 | 7 | 0 | 2 | 1 | 2 | 109 | 263 | 22 | 29 | .256 | .430 | .548 | .978 | .593 | .292 | .276 | 20.91 | 22.05 | 1.05 | 12.44 | 2017- UDFA -CLE | premium | premium | premium | MLB | 2025-2025 | 2018-2025 | 2021 |
| 11 | Bryan Lavastida | 22 | C | R | 118 | 48 | 165 | 32 | 50 | 12 | 0 | 5 | 31 | 14 | 5 | 26 | 30 | 3 | 0 | 4 | 2 | 1 | 77 | 198 | 17 | 33 | .303 | .399 | .467 | .866 | .376 | .164 | .336 | 13.13 | 15.15 | 1.15 | 33.00 | 2018- 15- 463-CLE | premium | premium | premium | MLB | 2022-2022 | 2018-2025 | 2021 |
| 27 | Micah Pries | 23 | LF | L | 110 | 45 | 161 | 19 | 43 | 6 | 1 | 7 | 21 | 8 | 1 | 12 | 55 | 6 | 0 | 0 | 0 | 1 | 72 | 179 | 14 | 29 | .267 | .341 | .447 | .788 | .298 | .180 | .364 | 6.70 | 30.73 | 4.58 | 23.00 | 2019- 13- 400-CLE | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 8 | Julian Escobedo | 23 | CF | L | 81 | 38 | 136 | 21 | 28 | 7 | 2 | 1 | 12 | 5 | 6 | 13 | 51 | 3 | 0 | 0 | 0 | 0 | 42 | 152 | 10 | 18 | .206 | .289 | .309 | .598 | .191 | .103 | .321 | 8.55 | 33.55 | 3.92 | 136.00 | 2019- 17- 520-CLE | premium | premium | premium | AA | 2017-2025 | 2021 | |
| 28 | Joe Donovan | 22 | C | R | 88* | 43 | 115 | 15 | 19 | 3 | 1 | 4 | 7 | 3 | 0 | 13 | 46 | 7 | 0 | 0 | 0 | 3 | 36 | 135 | 8 | 11 | .165 | .289 | .313 | .602 | .287 | .148 | .231 | 9.63 | 34.07 | 3.54 | 28.75 | 2017- 33-1005-CHN | premium | premium | premium | AAA | 2018-2024 | 2021 | |
| 26 | Michael Amditis | 23 | C | R | 94* | 34 | 104 | 15 | 20 | 7 | 0 | 4 | 14 | 1 | 0 | 14 | 28 | 2 | 1 | 0 | 0 | 3 | 39 | 121 | 11 | 9 | .192 | .300 | .375 | .675 | .327 | .183 | .222 | 11.57 | 23.14 | 2.00 | 26.00 | 2019- 21- 640-CLE | premium | premium | premium | AA | 2017-2023 | 2021 | |
| 43 | Jhonkensy Noel | 19 | 3B | R | 119* | 26 | 100 | 13 | 28 | 3 | 0 | 8 | 25 | 3 | 1 | 9 | 31 | 2 | 0 | 0 | 3 | 1 | 55 | 111 | 11 | 17 | .280 | .351 | .550 | .901 | .380 | .270 | .328 | 8.11 | 27.93 | 3.44 | 12.50 | 2017- UDFA -CLE | premium | premium | premium | MLB | 2024-2025 | 2018-2025 | 2021 |
| 10 | Austen Wade | 25 | RF | L | 86* | 34 | 94 | 19 | 17 | 2 | 0 | 2 | 9 | 1 | 1 | 20 | 23 | 0 | 0 | 1 | 0 | 1 | 25 | 115 | 4 | 13 | .181 | .322 | .266 | .588 | .298 | .085 | .214 | 17.39 | 20.00 | 1.15 | 47.00 | 2017- 5- 162-CLE | premium | premium | premium | AA | 2015-2021 | 2021 | |
| 8 | Daniel Schneemann | 24 | LF | L | 96* | 26 | 85 | 9 | 20 | 3 | 1 | 3 | 13 | 6 | 0 | 6 | 24 | 0 | 0 | 1 | 0 | 0 | 34 | 92 | 7 | 13 | .235 | .283 | .400 | .683 | .306 | .165 | .288 | 6.52 | 26.09 | 4.00 | 28.33 | 2018- 33-1003-CLE | premium | premium | premium | MLB | 2024-2025 | 2016-2025 | 2021 |
| 31 | Johnathan Rodriguez | 21 | RF | R | 92* | 24 | 79 | 9 | 17 | 4 | 0 | 2 | 11 | 2 | 1 | 9 | 22 | 2 | 0 | 0 | 0 | 3 | 27 | 90 | 6 | 11 | .215 | .311 | .342 | .653 | .253 | .127 | .273 | 10.00 | 24.44 | 2.44 | 39.50 | 2017- 3- 102-CLE | premium | premium | premium | MLB | 2024-2025 | 2017-2025 | 2021 |
| 4 | Christian Cairo | 20 | 2B-3B | R | 118* | 21 | 71 | 16 | 19 | 5 | 0 | 3 | 7 | 4 | 1 | 12 | 21 | 2 | 1 | 0 | 0 | 0 | 33 | 86 | 8 | 11 | .268 | .388 | .465 | .853 | .408 | .197 | .340 | 13.95 | 24.42 | 1.75 | 23.67 | 2019- 4- 130-CLE | premium | premium | premium | AAA | 2019-2025 | 2021 | |
| 43 | Jonathan Engelmann | 24 | RF | R | 84* | 22 | 67 | 9 | 12 | 5 | 0 | 0 | 7 | 3 | 0 | 12 | 20 | 1 | 0 | 2 | 0 | 0 | 17 | 82 | 5 | 7 | .179 | .305 | .254 | .559 | .299 | .075 | .245 | 14.63 | 24.39 | 1.67 | 0.00 | 2018- 31- 943-CLE | premium | premium | premium | AAA | 2016-2022 | 2021 | |
| 11 | Gianpaul Gonzalez | 25 | C | R | 15 | 46 | 3 | 11 | 3 | 0 | 0 | 5 | 1 | 0 | 5 | 18 | 0 | 0 | 0 | 0 | 2 | 14 | 51 | 3 | 8 | .239 | .314 | .304 | .618 | .196 | .065 | .393 | 9.80 | 35.29 | 3.60 | 0.00 | 2014- 20- 608-CLE | premium | premium | premium | AAA | 2014-2021 | 2021 | ||
| 16 | Wilfri Peralta | 20 | 2B | B | 14 | 29 | 5 | 6 | 1 | 0 | 0 | 7 | 3 | 1 | 7 | 14 | 3 | 0 | 0 | 0 | 0 | 7 | 39 | 1 | 5 | .207 | .410 | .241 | .651 | .345 | .034 | .400 | 17.95 | 35.90 | 2.00 | 0.00 | 2017- UDFA -CLE | premium | premium | premium | A+ | 2018-2022 | 2021 | ||
| 56 | Cody Farhat | 24 | LF | R | 8 | 28 | 7 | 8 | 2 | 0 | 2 | 3 | 1 | 1 | 1 | 5 | 2 | 0 | 0 | 0 | 1 | 16 | 31 | 4 | 4 | .286 | .355 | .571 | .926 | .321 | .285 | .286 | 3.23 | 16.13 | 5.00 | 14.00 | 2018- 23- 703-CLE | premium | premium | premium | A+ | 2016-2021 | 2021 | ||
| 8 | Clark Scolamiero | 25 | LF | L | 8 | 21 | 6 | 4 | 1 | 0 | 2 | 3 | 0 | 0 | 6 | 7 | 2 | 0 | 0 | 0 | 0 | 11 | 29 | 3 | 1 | .190 | .414 | .524 | .938 | .619 | .334 | .167 | 20.69 | 24.14 | 1.17 | 10.50 | 2017- 22- 672-CLE | premium | premium | premium | AA | 2015-2021 | 2021 | ||
| 11 | Angel Lopez | 24 | C | R | 5 | 16 | 2 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 1 | 6 | 17 | 2 | 1 | .188 | .235 | .375 | .610 | .250 | .187 | .273 | 5.88 | 29.41 | 5.00 | 0.00 | 2017- 13- 402-CLE | premium | premium | premium | AAA | 2017-2022 | 2021 | ||
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 31 | Harold Ramirez | 26 | LF | R | 4 | 13 | 1 | 4 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 7 | 13 | 1 | 3 | .308 | .308 | .538 | .846 | .231 | .230 | .273 | 0.00 | 7.69 | 0.00 | 13.00 | 2011- UDFA -PIT | premium | premium | premium | MLB | 2019-2024 | 2012-2025 | 2021 | |
| - | Bobby Bradley | 25 | 1B | L | 3 | 7 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | .000 | .222 | .000 | .222 | .286 | .000 | .000 | 22.22 | 44.44 | 2.00 | 0.00 | 2014- 3- 97-CLE | premium | premium | premium | MLB | 2019-2022 | 2014-2025 | 2021 | |
| 4 | Joab Gonzalez | 21 | 2B | R | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | .000 | .167 | .000 | .167 | .200 | .000 | .000 | 16.67 | 66.67 | 4.00 | 0.00 | 2019- 24- 730-CLE | premium | premium | premium | A+ | 2018-2021 | 2021 | ||
| 26 | Jonathan Lopez | 21 | P | L | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | 1.000 | .000 | 1.000 | .000 | .000 | .000 | 100.00 | 0.00 | 0.00 | 0.00 | 2016- UDFA -CLE | premium | premium | premium | AA | 2016-2021 | 2021 | ||
| Totals: | 1137 | 3840 | 554 | 908 | 176 | 21 | 117 | 503 | 151 | 58 | 457 | 1160 | 78 | 4 | 29 | 11 | 46 | 1477 | 4408 | 314 | 594 | .236 | .328 | .385 | .712 | .291 | .148 | .305 | 10.37 | 26.32 | 2.54 | 32.82 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 41 | Mason Hickman | 22 | R | 8 | 8 | 4.88 | 20 | 20 | 0 | 0 | 0 | 0 | 0 | 97.2 | 89 | 59 | 53 | 15 | 37 | 110 | 8 | 1 | 4 | 1.29 | 8.20 | 1.38 | 3.41 | 10.14 | 5.44 | 2.97 | 2020- 5- 154-CLE | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 44 | Hunter Gaddis | 23 | R | 4 | 11 | 4.16 | 20 | 19 | 1 | 0 | 1 | 1 | 0 | 97.1 | 83 | 65 | 45 | 20 | 28 | 127 | 6 | 1 | 11 | 1.14 | 7.67 | 1.85 | 2.59 | 11.74 | 6.01 | 4.54 | 2019- 5- 160-CLE | premium | premium | premium | MLB | 2022-2025 | 2017-2025 | 2021 |
| 46 | Raymond Burgos | 22 | L | 0 | 2 | 5.59 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 9.2 | 16 | 8 | 6 | 1 | 2 | 8 | 0 | 1 | 0 | 1.86 | 14.90 | 0.93 | 1.86 | 7.45 | 7.45 | 4.00 | 2016- 18- 542-CLE | premium | premium | premium | MLB | 2024-2024 | 2018-2025 | 2021 |
| 63 | Alex Royalty | 24 | R | 1 | 0 | 0.00 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 9.0 | 5 | 2 | 0 | 0 | 5 | 5 | 0 | 0 | 0 | 1.11 | 5.00 | 0.00 | 5.00 | 5.00 | 2.00 | 1.00 | 2018- 8- 253-CLE | premium | premium | premium | AA | 2016-2022 | 2021 | |
| 45 | Kevin Coulter | 24 | R | 9 | 4 | 5.10 | 23 | 13 | 0 | 0 | 10 | 2 | 0 | 77.2 | 86 | 47 | 44 | 9 | 26 | 73 | 4 | 2 | 3 | 1.44 | 9.97 | 1.04 | 3.01 | 8.46 | 5.45 | 2.81 | 2019- 33-1000-CLE | premium | premium | premium | AAA | 2016-2022 | 2021 | |
| 32 | Tanner Burns | 22 | R | 2 | 5 | 3.57 | 18 | 18 | 0 | 0 | 0 | 0 | 0 | 75.2 | 64 | 36 | 30 | 10 | 29 | 91 | 8 | 0 | 3 | 1.23 | 7.61 | 1.19 | 3.45 | 10.82 | 4.28 | 3.14 | 2020- 1- 36-CLE | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 22 | Nathan Ocker | 24 | R | 6 | 0 | 3.03 | 34 | 1 | 0 | 0 | 33 | 7 | 3 | 74.1 | 65 | 27 | 25 | 10 | 23 | 88 | 2 | 0 | 3 | 1.18 | 7.87 | 1.21 | 2.78 | 10.65 | 3.27 | 3.83 | 2019- 29- 880-CLE | premium | premium | premium | AAA | 2016-2022 | 2021 | |
| 30 | Tim Herrin | 24 | L | 4 | 3 | 2.57 | 36 | 0 | 0 | 0 | 36 | 9 | 2 | 73.2 | 60 | 30 | 21 | 3 | 32 | 85 | 11 | 1 | 2 | 1.25 | 7.33 | 0.37 | 3.91 | 10.38 | 3.67 | 2.66 | 2018- 29- 883-CLE | premium | premium | premium | MLB | 2023-2025 | 2016-2025 | 2021 |
| 10 | Xzavion Curry | 22 | R | 5 | 1 | 2.66 | 13 | 13 | 0 | 0 | 0 | 0 | 0 | 67.2 | 53 | 22 | 20 | 10 | 12 | 80 | 2 | 3 | 3 | 0.96 | 7.05 | 1.33 | 1.60 | 10.64 | 2.93 | 6.67 | 2019- 7- 220-CLE | premium | premium | premium | MLB | 2022-2025 | 2017-2025 | 2021 |
| 35 | Kevin Kelly | 23 | R | 5 | 5 | 4.66 | 40 | 0 | 0 | 0 | 40 | 26 | 7 | 56.0 | 56 | 33 | 29 | 7 | 8 | 81 | 1 | 0 | 1 | 1.14 | 9.00 | 1.13 | 1.29 | 13.02 | 5.30 | 10.13 | 2019- 19- 580-CLE | premium | premium | premium | MLB | 2023-2025 | 2017-2025 | 2021 |
| 24 | Jared Janczak | 26 | R | 5 | 0 | 4.72 | 35 | 0 | 0 | 0 | 35 | 11 | 1 | 55.1 | 46 | 35 | 29 | 8 | 38 | 65 | 7 | 1 | 7 | 1.52 | 7.48 | 1.30 | 6.18 | 10.57 | 5.69 | 1.71 | 2019- 31- 940-CLE | premium | premium | premium | AA | 2016-2022 | 2021 | |
| 9 | Nick Gallagher | 25 | R | 1 | 3 | 4.61 | 36 | 0 | 0 | 0 | 36 | 13 | 3 | 54.2 | 43 | 31 | 28 | 7 | 28 | 70 | 5 | 1 | 7 | 1.30 | 7.08 | 1.15 | 4.61 | 11.52 | 5.10 | 2.50 | 2017- 16- 492-CLE | premium | premium | premium | AAA | 2015-2023 | 2021 | |
| 29 | Logan Allen | 22 | L | 5 | 0 | 1.58 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 51.1 | 37 | 13 | 9 | 3 | 13 | 67 | 0 | 0 | 2 | 0.97 | 6.49 | 0.53 | 2.28 | 11.75 | 2.28 | 5.15 | 2020- 2- 56-CLE | premium | premium | premium | MLB | 2023-2025 | 2018-2025 | 2021 |
| - | Juan Zapata | 22 | R | 0 | 0 | 0.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 5.2 | 1 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 0.71 | 1.59 | 0.00 | 4.76 | 4.76 | 0.00 | 1.00 | 2018- UDFA -CLE | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 34 | Daniel Espino | 20 | R | 2 | 6 | 4.04 | 10 | 10 | 0 | 0 | 0 | 0 | 0 | 49.0 | 30 | 23 | 22 | 7 | 16 | 88 | 3 | 1 | 1 | 0.94 | 5.51 | 1.29 | 2.94 | 16.16 | 4.22 | 5.50 | 2019- 1- 24-CLE | premium | premium | premium | AAA | 2019-2025 | 2021 | |
| 36 | Zach Draper | 26 | L | 2 | 2 | 4.47 | 12 | 4 | 0 | 0 | 8 | 4 | 2 | 44.1 | 45 | 24 | 22 | 10 | 11 | 34 | 2 | 0 | 3 | 1.26 | 9.14 | 2.03 | 2.23 | 6.90 | 4.87 | 3.09 | 2017- 30- 912-CLE | premium | premium | premium | AAA | 2014-2022 | 2021 | |
| 13 | Aaron Civale | 26 | R | 0 | 0 | 0.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 4.1 | 1 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0.23 | 2.08 | 0.00 | 0.00 | 8.31 | 0.00 | 0.00 | 2016- 3- 92-CLE | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 17 | Thomas Ponticelli | 24 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 4.0 | 2 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0.50 | 4.50 | 0.00 | 0.00 | 11.25 | 0.00 | 0.00 | 2018- 12- 373-CLE | premium | premium | premium | AAA | 2016-2025 | 2021 | |
| 46 | Cade Smith | 22 | R | 0 | 0 | 0.00 | 3 | 0 | 0 | 0 | 3 | 3 | 1 | 3.0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0.33 | 0.00 | 0.00 | 3.00 | 12.00 | 0.00 | 4.00 | 2017- 16- 466-MIN | premium | premium | premium | MLB | 2024-2025 | 2018-2025 | 2021 |
| 29 | Jerson Ramirez | 22 | R | 3 | 0 | 3.21 | 20 | 0 | 0 | 0 | 20 | 17 | 11 | 28.0 | 21 | 14 | 10 | 1 | 10 | 38 | 4 | 0 | 2 | 1.11 | 6.75 | 0.32 | 3.21 | 12.21 | 4.50 | 3.80 | 2017- UDFA -CLE | premium | premium | premium | AA | 2018-2022 | 2021 | |
| 11 | Gianpaul Gonzalez | 25 | R | 0 | 0 | 13.50 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 2.0 | 3 | 3 | 3 | 1 | 1 | 0 | 1 | 0 | 0 | 2.00 | 13.50 | 4.50 | 4.50 | 0.00 | 13.50 | 0.00 | 2014- 20- 608-CLE | premium | premium | premium | AAA | 2014-2021 | 2021 | |
| 36 | Nic Enright | 24 | R | 1 | 0 | 1.47 | 11 | 0 | 0 | 0 | 11 | 4 | 3 | 18.1 | 12 | 3 | 3 | 0 | 3 | 32 | 1 | 1 | 0 | 0.82 | 5.89 | 0.00 | 1.47 | 15.71 | 1.47 | 10.67 | 2019- 20- 610-CLE | premium | premium | premium | MLB | 2025-2025 | 2016-2025 | 2021 |
| 40 | Kellen Rholl | 25 | L | 0 | 1 | 17.50 | 23 | 0 | 0 | 0 | 23 | 11 | 2 | 18.0 | 33 | 40 | 35 | 3 | 34 | 17 | 8 | 3 | 14 | 3.72 | 16.50 | 1.50 | 17.00 | 8.50 | 20.00 | 0.50 | 2018- 25- 763-CLE | premium | premium | premium | A+ | 2015-2021 | 2021 | |
| 34 | Matt Turner | 21 | L | 0 | 2 | 3.94 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 16.0 | 18 | 14 | 7 | 4 | 7 | 12 | 1 | 0 | 1 | 1.56 | 10.13 | 2.25 | 3.94 | 6.75 | 7.88 | 1.71 | 2017- 11- 342-CLE | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 47 | Eric Mock | 24 | R | 0 | 2 | 10.20 | 8 | 2 | 0 | 0 | 6 | 3 | 1 | 15.0 | 17 | 17 | 17 | 3 | 11 | 17 | 1 | 1 | 2 | 1.87 | 10.20 | 1.80 | 6.60 | 10.20 | 10.20 | 1.55 | 2019- 25- 760-CLE | premium | premium | premium | AAA | 2017-2022 | 2021 | |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 47 | Alec Wisely | 23 | R | 1 | 0 | 5.40 | 7 | 0 | 0 | 0 | 7 | 4 | 1 | 11.2 | 14 | 8 | 7 | 2 | 5 | 11 | 3 | 0 | 0 | 1.63 | 10.80 | 1.54 | 3.86 | 8.49 | 6.17 | 2.20 | 2019- 34-1030-CLE | premium | premium | premium | AA | 2016-2021 | 2021 | |
| 38 | Andrew Misiaszek | 23 | L | 1 | 0 | 5.91 | 7 | 0 | 0 | 0 | 7 | 0 | 0 | 10.2 | 11 | 11 | 7 | 2 | 6 | 18 | 1 | 0 | 1 | 1.59 | 9.28 | 1.69 | 5.06 | 15.19 | 9.28 | 3.00 | 2019- 32- 970-CLE | premium | premium | premium | AAA | 2016-2025 | 2021 | |
| 26 | Jonathan Lopez | 21 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 9.00 | 0.00 | 0.00 | 2016- UDFA -CLE | premium | premium | premium | AA | 2016-2021 | 2021 | |
| Totals: | 65 | 55 | 4.12 | 400 | 120 | 2 | 1 | 118 | 280 | 37 | 1031.0 | 911 | 565 | 472 | 136 | 389 | 1234 | 79 | 17 | 70 | 1.26 | 7.95 | 1.19 | 3.40 | 10.77 | 4.93 | 3.17 | premium | premium | premium |