| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 5 | Endy Rodriguez | 21 | C | B | 120 | 98 | 377 | 73 | 111 | 25 | 6 | 15 | 73 | 2 | 0 | 50 | 77 | 4 | 0 | 3 | 0 | 8 | 193 | 434 | 46 | 65 | .294 | .380 | .512 | .892 | .355 | .218 | .333 | 11.52 | 17.74 | 1.54 | 25.13 | 2018- UDFA -NYN | premium | premium | premium | MLB | 2023-2025 | 2018-2025 | 2021 |
| 52 | Dariel Lopez | 19 | 3B-SS | R | 100 | 98 | 361 | 52 | 93 | 17 | 1 | 10 | 64 | 1 | 2 | 41 | 103 | 8 | 0 | 6 | 0 | 10 | 142 | 416 | 28 | 65 | .258 | .341 | .393 | .734 | .247 | .135 | .327 | 9.86 | 24.76 | 2.51 | 36.10 | 2018- UDFA -PIT | premium | premium | premium | A+ | 2019-2022 | 2021 | |
| 2 | Jase Bowen | 20 | 2B-CF | R | 97 | 103 | 354 | 51 | 78 | 12 | 2 | 14 | 60 | 16 | 1 | 32 | 111 | 15 | 0 | 4 | 0 | 6 | 136 | 405 | 28 | 50 | .220 | .309 | .384 | .693 | .297 | .164 | .275 | 7.90 | 27.41 | 3.47 | 25.29 | 2019- 11- 334-PIT | premium | premium | premium | AAA | 2019-2025 | 2021 | |
| 17 | Hudson Head | 20 | RF-CF | L | 106 | 101 | 348 | 67 | 74 | 16 | 1 | 15 | 50 | 3 | 1 | 68 | 137 | 15 | 0 | 3 | 0 | 2 | 137 | 434 | 32 | 42 | .213 | .362 | .394 | .756 | .382 | .181 | .296 | 15.67 | 31.57 | 2.01 | 23.20 | 2019- 3- 84-SDN | premium | premium | premium | AA | 2019-2025 | 2021 | |
| 33 | Maikol Escotto | 19 | SS | R | 101 | 89 | 320 | 61 | 75 | 13 | 1 | 7 | 38 | 22 | 5 | 54 | 116 | 6 | 0 | 1 | 0 | 2 | 111 | 381 | 21 | 54 | .234 | .354 | .347 | .701 | .334 | .113 | .343 | 14.17 | 30.45 | 2.15 | 45.71 | 2018- UDFA -NYA | premium | premium | premium | AA | 2019-2025 | 2021 | |
| 28 | Alexander Mojica | 18 | 3B | R | 93 | 87 | 287 | 38 | 60 | 11 | 0 | 9 | 43 | 1 | 0 | 41 | 90 | 8 | 0 | 3 | 0 | 6 | 98 | 339 | 20 | 40 | .209 | .322 | .341 | .663 | .279 | .132 | .267 | 12.09 | 26.55 | 2.20 | 31.89 | 2018- UDFA -PIT | premium | premium | premium | A | 2019-2023 | 2021 | |
| 14 | Ernny Ordonez | 22 | 1B | R | 100 | 75 | 258 | 37 | 65 | 14 | 3 | 7 | 45 | 1 | 0 | 24 | 64 | 3 | 0 | 2 | 0 | 5 | 106 | 287 | 24 | 41 | .252 | .321 | .411 | .732 | .256 | .159 | .307 | 8.36 | 22.30 | 2.67 | 36.86 | 2019- 33- 994-PIT | premium | premium | premium | A+ | 2018-2025 | 2021 | |
| 13 | Jack Herman | 21 | LF | R | 109 | 54 | 217 | 39 | 55 | 11 | 1 | 13 | 49 | 2 | 1 | 23 | 70 | 1 | 0 | 2 | 1 | 6 | 107 | 243 | 25 | 30 | .253 | .325 | .493 | .818 | .350 | .240 | .309 | 9.47 | 28.81 | 3.04 | 16.69 | 2018- 30- 894-PIT | premium | premium | premium | A+ | 2018-2024 | 2021 | |
| 25 | Sammy Siani | 20 | LF-RF | L | 108 | 62 | 200 | 48 | 43 | 7 | 2 | 8 | 35 | 9 | 2 | 52 | 63 | 2 | 0 | 4 | 0 | 4 | 78 | 258 | 17 | 26 | .215 | .376 | .390 | .766 | .470 | .175 | .263 | 20.16 | 24.42 | 1.21 | 25.00 | 2019- 1- 37-PIT | premium | premium | premium | AAA | 2019-2025 | 2021 | |
| 13 | Sergio Campana | 19 | CF-RF | R | 79 | 51 | 160 | 27 | 27 | 5 | 3 | 0 | 9 | 13 | 1 | 24 | 67 | 2 | 0 | 2 | 0 | 2 | 38 | 188 | 8 | 19 | .169 | .282 | .238 | .520 | .294 | .069 | .284 | 12.77 | 35.64 | 2.79 | 0.00 | 2018- UDFA -PIT | premium | premium | premium | A+ | 2019-2024 | 2021 | |
| 3 | Norkis Marcos | 20 | SS-1B | R | 82 | 40 | 119 | 18 | 23 | 4 | 1 | 0 | 14 | 7 | 3 | 21 | 50 | 1 | 0 | 2 | 0 | 1 | 29 | 143 | 5 | 18 | .193 | .315 | .244 | .559 | .261 | .051 | .324 | 14.69 | 34.97 | 2.38 | 0.00 | 2017- UDFA -PIT | premium | premium | premium | AA | 2018-2023 | 2021 | |
| 12 | Eli Wilson | 22 | C | R | 131 | 39 | 116 | 23 | 38 | 8 | 0 | 3 | 22 | 0 | 0 | 31 | 38 | 4 | 0 | 1 | 0 | 1 | 55 | 152 | 11 | 27 | .328 | .480 | .474 | .954 | .414 | .146 | .461 | 20.39 | 25.00 | 1.23 | 38.67 | 2019- 16- 484-PIT | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 23 | Daniel Rivero | 20 | RF | R | 99 | 40 | 108 | 17 | 26 | 3 | 2 | 1 | 14 | 1 | 2 | 25 | 20 | 0 | 0 | 1 | 1 | 2 | 36 | 134 | 6 | 20 | .241 | .381 | .333 | .714 | .315 | .092 | .284 | 18.66 | 14.93 | 0.80 | 108.00 | 2017- UDFA -PIT | premium | premium | premium | A | 2018-2022 | 2021 | |
| 3 | Francisco Acuna | 21 | 2B-3B | R | 100 | 39 | 101 | 22 | 21 | 7 | 0 | 1 | 9 | 0 | 1 | 20 | 27 | 9 | 0 | 1 | 0 | 3 | 31 | 131 | 8 | 13 | .208 | .382 | .307 | .689 | .287 | .099 | .270 | 15.27 | 20.61 | 1.35 | 101.00 | 2016- UDFA -PIT | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 10 | Jackson Glenn | 23 | 2B | R | 126* | 28 | 101 | 22 | 34 | 12 | 1 | 0 | 14 | 1 | 1 | 22 | 21 | 0 | 0 | 1 | 0 | 1 | 48 | 124 | 13 | 21 | .337 | .452 | .475 | .927 | .356 | .138 | .420 | 17.74 | 16.94 | 0.95 | 0.00 | 2021- 5- 133-PIT | premium | premium | premium | AAA | 2017-2024 | 2021 | |
| 32 | Jasiah Dixon | 19 | LF-RF | R | 82* | 27 | 97 | 14 | 17 | 2 | 0 | 0 | 4 | 13 | 0 | 13 | 34 | 4 | 1 | 0 | 0 | 1 | 19 | 115 | 2 | 15 | .175 | .298 | .196 | .494 | .289 | .021 | .270 | 11.30 | 29.57 | 2.62 | 0.00 | 2019- 23- 694-PIT | premium | premium | premium | A | 2019-2022 | 2021 | |
| 27 | Abrahan Gutierrez | 21 | C | R | 120 | 22 | 68 | 16 | 20 | 8 | 2 | 0 | 4 | 0 | 0 | 16 | 13 | 3 | 0 | 0 | 0 | 3 | 32 | 87 | 10 | 10 | .294 | .448 | .471 | .919 | .412 | .177 | .364 | 18.39 | 14.94 | 0.81 | 0.00 | 2016- UDFA -ATL | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 10 | Yoyner Fajardo | 22 | 2B | L | 124* | 31 | 68 | 9 | 21 | 4 | 2 | 1 | 12 | 8 | 0 | 8 | 15 | 2 | 0 | 0 | 0 | 1 | 32 | 78 | 7 | 14 | .309 | .397 | .471 | .868 | .397 | .162 | .385 | 10.26 | 19.23 | 1.88 | 68.00 | 2018- UDFA -PIT | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 54 | Kyle Wilkie | 23 | C | R | 17 | 48 | 7 | 13 | 4 | 0 | 1 | 6 | 0 | 0 | 5 | 10 | 0 | 0 | 0 | 0 | 1 | 20 | 53 | 5 | 8 | .271 | .340 | .417 | .757 | .250 | .146 | .324 | 9.43 | 18.87 | 2.00 | 48.00 | 2019- 12- 364-PIT | premium | premium | premium | A+ | 2017-2021 | 2021 | ||
| 51 | Blake Sabol | 23 | LF-C | L | 14 | 46 | 11 | 17 | 2 | 0 | 2 | 12 | 0 | 2 | 12 | 12 | 1 | 0 | 0 | 0 | 0 | 25 | 59 | 4 | 13 | .370 | .508 | .543 | 1.051 | .391 | .173 | .469 | 20.34 | 20.34 | 1.00 | 23.00 | 2019- 7- 214-PIT | premium | premium | premium | MLB | 2023-2025 | 2017-2025 | 2021 | |
| 10 | William Matthiessen | 23 | 1B | R | 12 | 39 | 6 | 10 | 3 | 1 | 2 | 11 | 0 | 0 | 12 | 21 | 0 | 0 | 0 | 0 | 1 | 21 | 51 | 6 | 4 | .256 | .431 | .538 | .969 | .590 | .282 | .500 | 23.53 | 41.18 | 1.75 | 19.50 | 2019- 6- 184-PIT | premium | premium | premium | AA | 2017-2023 | 2021 | ||
| 29 | Dylan Shockley | 24 | C | R | 8 | 26 | 7 | 8 | 2 | 0 | 0 | 6 | 0 | 0 | 5 | 9 | 2 | 0 | 0 | 0 | 0 | 10 | 33 | 2 | 6 | .308 | .455 | .385 | .840 | .269 | .077 | .471 | 15.15 | 27.27 | 1.80 | 0.00 | 2019- 34-1024-PIT | premium | premium | premium | AAA | 2017-2025 | 2021 | ||
| 18 | Claudio Finol | 21 | 3B-2B | R | 6 | 17 | 2 | 3 | 0 | 0 | 0 | 1 | 1 | 1 | 2 | 2 | 1 | 0 | 0 | 0 | 1 | 3 | 20 | 0 | 3 | .176 | .300 | .176 | .476 | .118 | .000 | .200 | 10.00 | 10.00 | 1.00 | 0.00 | 2016- UDFA -CIN | premium | premium | premium | AA | 2017-2025 | 2021 | ||
| 18 | Jake Snider | 23 | LF | L | 7 | 13 | 7 | 6 | 1 | 0 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 0 | 7 | 18 | 1 | 5 | .462 | .611 | .538 | 1.149 | .462 | .076 | .545 | 27.78 | 11.11 | 0.40 | 0.00 | 2019- 20- 604-PIT | premium | premium | premium | AA | 2017-2025 | 2021 | ||
| 27 | Ethan Goforth | 24 | C-1B | R | 4 | 7 | 1 | 2 | 0 | 0 | 0 | 1 | 3 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 2 | 8 | 0 | 2 | .286 | .375 | .286 | .661 | .571 | .000 | .500 | 12.50 | 37.50 | 3.00 | 0.00 | 2019- 25- 754-PIT | premium | premium | premium | A | 2017-2021 | 2021 | ||
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| Totals: | 1152 | 3856 | 675 | 940 | 191 | 29 | 109 | 596 | 104 | 23 | 607 | 1175 | 91 | 1 | 36 | 2 | 67 | 1516 | 4591 | 329 | 611 | .244 | .357 | .393 | .750 | .328 | .149 | .319 | 13.22 | 25.59 | 1.94 | 35.38 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 45 | Adrian Florencio | 22 | R | 6 | 4 | 2.46 | 20 | 19 | 0 | 0 | 1 | 0 | 0 | 95.0 | 70 | 35 | 26 | 5 | 30 | 117 | 3 | 2 | 9 | 1.05 | 6.63 | 0.47 | 2.84 | 11.08 | 3.32 | 3.90 | 2019- UDFA -PIT | premium | premium | premium | A+ | 2019-2022 | 2021 | |
| 41 | Luis Ortiz | 22 | R | 5 | 3 | 3.09 | 22 | 19 | 0 | 0 | 3 | 1 | 0 | 87.1 | 82 | 46 | 30 | 5 | 28 | 113 | 8 | 2 | 5 | 1.26 | 8.45 | 0.52 | 2.89 | 11.65 | 4.74 | 4.04 | 2018- UDFA -PIT | premium | premium | premium | MLB | 2022-2025 | 2019-2025 | 2021 |
| 26 | Logan Hofmann | 21 | R | 6 | 4 | 3.59 | 22 | 13 | 0 | 0 | 9 | 3 | 0 | 82.2 | 59 | 40 | 33 | 12 | 33 | 103 | 4 | 0 | 8 | 1.11 | 6.42 | 1.31 | 3.59 | 11.21 | 4.35 | 3.12 | 2020- 5- 138-PIT | premium | premium | premium | A+ | 2019-2024 | 2021 | |
| 34 | Nick Garcia | 22 | R | 5 | 4 | 4.22 | 21 | 13 | 0 | 0 | 8 | 3 | 1 | 74.2 | 66 | 48 | 35 | 9 | 35 | 83 | 9 | 0 | 11 | 1.35 | 7.96 | 1.08 | 4.22 | 10.00 | 5.79 | 2.37 | 2020- 3- 79-PIT | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 36 | Tyler Samaniego | 22 | L | 1 | 0 | 1.29 | 5 | 0 | 0 | 0 | 5 | 2 | 0 | 7.0 | 4 | 2 | 1 | 1 | 2 | 15 | 1 | 0 | 0 | 0.86 | 5.14 | 1.29 | 2.57 | 19.29 | 2.57 | 7.50 | 2021- 15- 433-PIT | premium | premium | premium | AA | 2020-2025 | 2021 | |
| 30 | Eddy Yean | 20 | R | 5 | 2 | 5.26 | 22 | 8 | 0 | 0 | 14 | 3 | 1 | 66.2 | 56 | 45 | 39 | 8 | 39 | 69 | 5 | 2 | 5 | 1.42 | 7.56 | 1.08 | 5.26 | 9.31 | 6.07 | 1.77 | 2017- UDFA -WAS | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 37 | Jared Jones | 19 | R | 3 | 6 | 4.64 | 18 | 15 | 0 | 0 | 3 | 0 | 0 | 66.0 | 63 | 44 | 34 | 6 | 34 | 103 | 4 | 0 | 11 | 1.47 | 8.59 | 0.82 | 4.64 | 14.05 | 6.00 | 3.03 | 2020- 2- 44-PIT | premium | premium | premium | MLB | 2024-2024 | 2021-2024 | 2021 |
| 50 | Santiago Florez | 21 | R | 5 | 2 | 1.37 | 10 | 9 | 2 | 1 | 1 | 1 | 1 | 52.2 | 31 | 10 | 8 | 0 | 14 | 71 | 3 | 1 | 3 | 0.85 | 5.30 | 0.00 | 2.39 | 12.13 | 1.71 | 5.07 | 2016- UDFA -PIT | premium | premium | premium | A+ | 2017-2025 | 2021 | |
| 36 | Jose Maldonado | 22 | R | 0 | 0 | 1.59 | 3 | 2 | 0 | 0 | 1 | 0 | 0 | 5.2 | 1 | 1 | 1 | 0 | 4 | 11 | 0 | 0 | 0 | 0.88 | 1.59 | 0.00 | 6.35 | 17.47 | 1.59 | 2.75 | 2017- UDFA -PIT | premium | premium | premium | A | 2018-2021 | 2021 | |
| 48 | Alex Aquino | 24 | R | 0 | 0 | 0.00 | 4 | 0 | 0 | 0 | 4 | 2 | 2 | 5.0 | 0 | 0 | 0 | 0 | 2 | 8 | 0 | 1 | 0 | 0.40 | 0.00 | 0.00 | 3.60 | 14.40 | 0.00 | 4.00 | 2014- UDFA -ATL | premium | premium | premium | A | 2015-2021 | 2021 | |
| 31 | Domingo Gonzalez | 21 | R | 3 | 3 | 3.72 | 12 | 8 | 0 | 0 | 4 | 2 | 0 | 48.1 | 38 | 27 | 20 | 8 | 20 | 69 | 1 | 3 | 6 | 1.20 | 7.08 | 1.49 | 3.72 | 12.85 | 5.03 | 3.45 | 2018- UDFA -PIT | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 15 | Sergio Umana | 21 | R | 0 | 4 | 6.21 | 23 | 0 | 0 | 0 | 23 | 9 | 3 | 42.0 | 59 | 35 | 29 | 5 | 5 | 27 | 5 | 1 | 4 | 1.52 | 12.64 | 1.07 | 1.07 | 5.79 | 7.50 | 5.40 | 2018- UDFA -PIT | premium | premium | premium | A+ | 2019-2023 | 2021 | |
| - | Miguel Yajure | 23 | R | 0 | 1 | 6.75 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 4.0 | 6 | 5 | 3 | 1 | 1 | 5 | 0 | 0 | 0 | 1.75 | 13.50 | 2.25 | 2.25 | 11.25 | 11.25 | 5.00 | 2015- UDFA -NYA | premium | premium | premium | MLB | 2020-2022 | 2015-2025 | 2021 |
| 24 | Wandi Montout | 24 | R | 6 | 0 | 4.66 | 24 | 0 | 0 | 0 | 24 | 6 | 1 | 38.2 | 29 | 22 | 20 | 1 | 30 | 52 | 8 | 1 | 8 | 1.53 | 6.75 | 0.23 | 6.98 | 12.10 | 5.12 | 1.73 | 2019- UDFA -PIT | premium | premium | premium | A+ | 2019-2022 | 2021 | |
| 43 | Oliver Mateo | 23 | R | 5 | 2 | 4.78 | 33 | 0 | 0 | 0 | 33 | 20 | 7 | 37.2 | 17 | 21 | 20 | 2 | 40 | 82 | 22 | 0 | 7 | 1.51 | 4.06 | 0.48 | 9.56 | 19.59 | 5.02 | 2.05 | 2018- UDFA -PIT | premium | premium | premium | A+ | 2018-2024 | 2021 | |
| 55 | Cameron Junker | 23 | R | 2 | 0 | 3.00 | 14 | 0 | 0 | 0 | 14 | 3 | 1 | 30.0 | 14 | 12 | 10 | 2 | 20 | 47 | 2 | 0 | 2 | 1.13 | 4.20 | 0.60 | 6.00 | 14.10 | 3.60 | 2.35 | 2019- 10- 304-PIT | premium | premium | premium | AAA | 2017-2024 | 2021 | |
| 18 | Jose Soriano | 22 | R | 0 | 0 | 14.73 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 3.2 | 6 | 7 | 6 | 0 | 3 | 6 | 0 | 0 | 0 | 2.45 | 14.73 | 0.00 | 7.36 | 14.73 | 17.18 | 2.00 | 2016- UDFA -ANA | premium | premium | premium | MLB | 2023-2025 | 2016-2025 | 2021 |
| 22 | Brennan Malone | 20 | R | 0 | 0 | 0.00 | 3 | 0 | 0 | 0 | 3 | 1 | 0 | 3.2 | 4 | 4 | 0 | 0 | 5 | 2 | 1 | 0 | 1 | 2.45 | 9.82 | 0.00 | 12.27 | 4.91 | 9.82 | 0.40 | 2019- 1- 33-ARI | premium | premium | premium | A | 2019-2025 | 2021 | |
| 54 | Kyle Wilkie | 23 | R | 0 | 0 | 7.36 | 3 | 0 | 0 | 0 | 3 | 2 | 0 | 3.2 | 4 | 3 | 3 | 1 | 3 | 2 | 0 | 0 | 0 | 1.91 | 9.82 | 2.45 | 7.36 | 4.91 | 7.36 | 0.67 | 2019- 12- 364-PIT | premium | premium | premium | A+ | 2017-2021 | 2021 | |
| 51 | Drake Fellows | 23 | R | 1 | 0 | 9.82 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 3.2 | 5 | 4 | 4 | 1 | 6 | 4 | 1 | 0 | 0 | 3.00 | 12.27 | 2.45 | 14.73 | 9.82 | 9.82 | 0.67 | 2019- 6- 173-SDN | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 54 | Xavier Concepcion | 23 | R | 0 | 0 | 7.36 | 3 | 0 | 0 | 0 | 3 | 2 | 1 | 3.2 | 4 | 5 | 3 | 0 | 4 | 2 | 0 | 0 | 1 | 2.18 | 9.82 | 0.00 | 9.82 | 4.91 | 12.27 | 0.50 | 2018- UDFA -PIT | premium | premium | premium | A | 2018-2022 | 2021 | |
| - | Austin Davis | 28 | L | 0 | 0 | 3.00 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 3.0 | 2 | 1 | 1 | 0 | 1 | 6 | 1 | 0 | 0 | 1.00 | 6.00 | 0.00 | 3.00 | 18.00 | 3.00 | 6.00 | 2014- 12- 352-PHI | premium | premium | premium | MLB | 2018-2024 | 2012-2025 | 2021 |
| - | Enmanuel Mejia | 22 | R | 4 | 1 | 0.00 | 21 | 0 | 0 | 0 | 21 | 18 | 8 | 26.1 | 15 | 4 | 0 | 0 | 17 | 35 | 8 | 0 | 0 | 1.22 | 5.13 | 0.00 | 5.81 | 11.96 | 1.37 | 2.06 | 2019- UDFA -PIT | premium | premium | premium | AAA | 2019-2025 | 2021 | |
| 23 | Parker Brahms | 23 | R | 1 | 2 | 9.24 | 18 | 0 | 0 | 0 | 18 | 7 | 0 | 25.1 | 29 | 28 | 26 | 4 | 29 | 36 | 4 | 1 | 8 | 2.29 | 10.30 | 1.42 | 10.30 | 12.79 | 9.95 | 1.24 | 2020- UDFA -PIT | premium | premium | premium | A | 2017-2025 | 2021 | |
| 32 | Alex Roth | 23 | R | 1 | 0 | 4.13 | 17 | 1 | 0 | 0 | 16 | 8 | 0 | 24.0 | 21 | 12 | 11 | 6 | 18 | 29 | 0 | 0 | 1 | 1.63 | 7.88 | 2.25 | 6.75 | 10.88 | 4.50 | 1.61 | 2019- 21- 634-PIT | premium | premium | premium | A | 2017-2021 | 2021 | |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 26 | Ryan Troutman | 24 | R | 2 | 1 | 9.00 | 16 | 0 | 0 | 0 | 16 | 1 | 0 | 23.0 | 24 | 25 | 23 | 2 | 31 | 22 | 4 | 0 | 1 | 2.39 | 9.39 | 0.78 | 12.13 | 8.61 | 9.78 | 0.71 | 2019- 26- 784-PIT | premium | premium | premium | A | 2016-2021 | 2021 | |
| 31 | Carlos Campos | 20 | R | 2 | 2 | 4.84 | 13 | 1 | 0 | 0 | 12 | 5 | 0 | 22.1 | 25 | 15 | 12 | 6 | 10 | 25 | 4 | 0 | 2 | 1.57 | 10.07 | 2.42 | 4.03 | 10.07 | 6.04 | 2.50 | 2018- UDFA -PIT | premium | premium | premium | A+ | 2018-2022 | 2021 | |
| 34 | Denny Roman | 22 | L | 3 | 2 | 6.33 | 11 | 0 | 0 | 0 | 11 | 1 | 1 | 21.1 | 27 | 15 | 15 | 3 | 14 | 21 | 2 | 0 | 0 | 1.92 | 11.39 | 1.27 | 5.91 | 8.86 | 6.33 | 1.50 | 2018- UDFA -PIT | premium | premium | premium | A+ | 2018-2025 | 2021 | |
| 12 | Nick Dombkowski | 22 | L | 1 | 0 | 3.86 | 11 | 0 | 0 | 0 | 11 | 8 | 2 | 18.2 | 13 | 8 | 8 | 3 | 6 | 23 | 0 | 0 | 1 | 1.02 | 6.27 | 1.45 | 2.89 | 11.09 | 3.86 | 3.83 | 2021- UDFA -PIT | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 39 | Justin Meis | 21 | R | 1 | 1 | 2.04 | 10 | 0 | 0 | 0 | 10 | 2 | 0 | 17.2 | 14 | 9 | 4 | 2 | 9 | 27 | 1 | 0 | 0 | 1.30 | 7.13 | 1.02 | 4.58 | 13.75 | 4.58 | 3.00 | 2021- 10- 283-PIT | premium | premium | premium | AA | 2019-2025 | 2021 | |
| 15 | J.C. Flowers | 23 | R | 0 | 1 | 2.12 | 6 | 2 | 0 | 0 | 4 | 3 | 0 | 17.0 | 11 | 4 | 4 | 1 | 3 | 23 | 1 | 0 | 0 | 0.82 | 5.82 | 0.53 | 1.59 | 12.18 | 2.12 | 7.67 | 2019- 4- 124-PIT | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 29 | Steven Jennings | 22 | R | 2 | 0 | 2.76 | 6 | 0 | 0 | 0 | 6 | 1 | 1 | 16.1 | 14 | 5 | 5 | 1 | 5 | 19 | 2 | 0 | 0 | 1.16 | 7.71 | 0.55 | 2.76 | 10.47 | 2.76 | 3.80 | 2017- 2- 42-PIT | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 18 | Po-Yu Chen | 19 | R | 1 | 1 | 5.63 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 16.0 | 15 | 12 | 10 | 2 | 12 | 15 | 1 | 2 | 3 | 1.69 | 8.44 | 1.13 | 6.75 | 8.44 | 6.75 | 1.25 | 2020- UDFA -PIT | premium | premium | premium | AAA | 2021-2025 | 2021 | |
| 22 | Cristian Charle | 21 | R | 0 | 2 | 6.55 | 5 | 0 | 0 | 0 | 5 | 1 | 0 | 11.0 | 14 | 11 | 8 | 1 | 3 | 10 | 2 | 0 | 0 | 1.55 | 11.45 | 0.82 | 2.45 | 8.18 | 9.00 | 3.33 | 2018- UDFA -PIT | premium | premium | premium | AAA | 2018-2023 | 2021 | |
| - | Steven Brault | 29 | L | 0 | 0 | 0.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1.2 | 1 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 1.80 | 5.40 | 0.00 | 10.80 | 16.20 | 0.00 | 1.50 | 2013- 11- 339-BAL | premium | premium | premium | MLB | 2016-2022 | 2013-2023 | 2021 |
| 54 | Estalin Ortiz | 22 | L | 0 | 0 | 67.50 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 1.1 | 5 | 10 | 10 | 2 | 5 | 2 | 0 | 0 | 2 | 7.50 | 33.75 | 13.50 | 33.75 | 13.50 | 67.50 | 0.40 | 2018- UDFA -PIT | premium | premium | premium | A | 2018-2025 | 2021 | |
| 3 | Francisco Acuna | 21 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 2 | 3 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 4.00 | 18.00 | 0.00 | 18.00 | 9.00 | 27.00 | 0.50 | 2016- UDFA -PIT | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 5 | Endy Rodriguez | 21 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0.2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.50 | 13.50 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2018- UDFA -NYN | premium | premium | premium | MLB | 2023-2025 | 2018-2025 | 2021 |
| 3 | Norkis Marcos | 20 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0.0 | 2 | 5 | 5 | 0 | 3 | 0 | 0 | 0 | 1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2017- UDFA -PIT | premium | premium | premium | AA | 2018-2023 | 2021 | |
| Totals: | 71 | 48 | 4.17 | 414 | 119 | 2 | 1 | 117 | 295 | 30 | 1008.1 | 853 | 583 | 467 | 100 | 528 | 1288 | 107 | 16 | 100 | 1.37 | 7.61 | 0.89 | 4.71 | 11.50 | 5.20 | 2.44 | premium | premium | premium |