| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 24 | Wilyer Abreu | 22 | RF-CF | L | 112 | 82 | 287 | 52 | 77 | 15 | 1 | 16 | 50 | 10 | 11 | 38 | 99 | 5 | 0 | 1 | 0 | 1 | 142 | 331 | 32 | 45 | .268 | .363 | .495 | .858 | .355 | .227 | .353 | 11.48 | 29.91 | 2.61 | 17.94 | 2017- UDFA -HOU | premium | premium | premium | MLB | 2023-2025 | 2017-2025 | 2021 |
| 2 | Enmanuel Valdez | 22 | 2B-3B | L | 111 | 75 | 283 | 52 | 72 | 16 | 1 | 21 | 72 | 5 | 1 | 25 | 67 | 2 | 0 | 6 | 0 | 2 | 153 | 316 | 38 | 34 | .254 | .313 | .541 | .854 | .389 | .287 | .254 | 7.91 | 21.20 | 2.68 | 13.48 | 2015- UDFA -HOU | premium | premium | premium | MLB | 2023-2025 | 2016-2025 | 2021 |
| 7 | Freudis Nova | 21 | SS | R | 89 | 73 | 254 | 33 | 57 | 14 | 1 | 4 | 19 | 9 | 1 | 26 | 91 | 2 | 0 | 0 | 0 | 6 | 85 | 282 | 19 | 38 | .224 | .301 | .335 | .636 | .244 | .111 | .333 | 9.22 | 32.27 | 3.50 | 63.50 | 2016- UDFA -HOU | premium | premium | premium | A+ | 2017-2023 | 2021 | |
| 15 | C.J. Stubbs | 24 | C-1B | R | 99 | 67 | 253 | 40 | 58 | 15 | 3 | 12 | 35 | 6 | 4 | 23 | 104 | 2 | 0 | 2 | 0 | 4 | 115 | 280 | 30 | 28 | .229 | .296 | .455 | .751 | .324 | .226 | .331 | 8.21 | 37.14 | 4.52 | 21.08 | 2019- 10- 316-HOU | premium | premium | premium | MLB | 2025-2025 | 2016-2025 | 2021 |
| 9 | Shay Whitcomb | 22 | SS-3B | R | 127 | 58 | 233 | 49 | 70 | 22 | 0 | 16 | 56 | 16 | 3 | 19 | 81 | 3 | 0 | 2 | 0 | 4 | 140 | 257 | 38 | 32 | .300 | .358 | .601 | .959 | .438 | .301 | .391 | 7.39 | 31.52 | 4.26 | 14.56 | 2020- 5- 160-HOU | premium | premium | premium | MLB | 2024-2025 | 2018-2025 | 2021 |
| 14 | Alex Holderbach | 24 | C-1B | R | 96 | 63 | 220 | 38 | 49 | 7 | 0 | 12 | 36 | 1 | 1 | 24 | 106 | 1 | 0 | 2 | 0 | 5 | 92 | 247 | 19 | 30 | .223 | .300 | .418 | .718 | .305 | .195 | .356 | 9.72 | 42.91 | 4.42 | 18.33 | 2018- 16- 492-HOU | premium | premium | premium | AA | 2016-2022 | 2021 | |
| 12 | Matthew Barefoot | 23 | CF | R | 118 | 49 | 195 | 26 | 56 | 14 | 1 | 12 | 35 | 7 | 2 | 12 | 64 | 4 | 0 | 0 | 0 | 1 | 108 | 211 | 27 | 29 | .287 | .341 | .554 | .895 | .354 | .267 | .370 | 5.69 | 30.33 | 5.33 | 16.25 | 2019- 6- 196-HOU | premium | premium | premium | AA | 2017-2023 | 2021 | |
| 11 | J.C. Correa | 22 | 2B-3B | R | 104 | 45 | 185 | 33 | 58 | 13 | 0 | 4 | 25 | 3 | 2 | 7 | 29 | 0 | 0 | 1 | 0 | 1 | 83 | 193 | 17 | 41 | .314 | .337 | .449 | .786 | .178 | .135 | .353 | 3.63 | 15.03 | 4.14 | 46.25 | 2019- 38-1156-HOU | premium | premium | premium | AA | 2018-2024 | 2021 | |
| 3 | Luis Santana | 21 | 2B-3B | R | 94 | 49 | 170 | 23 | 39 | 10 | 0 | 6 | 24 | 5 | 2 | 13 | 43 | 5 | 0 | 2 | 0 | 2 | 67 | 190 | 16 | 23 | .229 | .300 | .394 | .694 | .259 | .165 | .268 | 6.84 | 22.63 | 3.31 | 28.33 | 2016- UDFA -NYN | premium | premium | premium | AAA | 2016-2024 | 2021 | |
| 23 | Alex McKenna | 23 | CF | R | 132 | 41 | 164 | 41 | 50 | 8 | 2 | 13 | 31 | 7 | 1 | 21 | 62 | 3 | 0 | 2 | 0 | 1 | 101 | 190 | 23 | 27 | .305 | .389 | .616 | 1.005 | .476 | .311 | .407 | 11.05 | 32.63 | 2.95 | 12.62 | 2018- 4- 132-HOU | premium | premium | premium | AAA | 2016-2023 | 2021 | |
| 33 | Scott Schreiber | 25 | 1B | R | 125 | 41 | 160 | 37 | 51 | 7 | 2 | 10 | 29 | 6 | 3 | 15 | 41 | 2 | 0 | 1 | 0 | 0 | 92 | 178 | 19 | 32 | .319 | .382 | .575 | .957 | .369 | .256 | .373 | 8.43 | 23.03 | 2.73 | 16.00 | 2018- 9- 282-HOU | premium | premium | premium | AA | 2015-2023 | 2021 | |
| 1 | Deury Carrasco | 21 | SS | L | 100 | 42 | 146 | 29 | 33 | 11 | 1 | 4 | 18 | 2 | 2 | 25 | 67 | 1 | 0 | 0 | 0 | 3 | 58 | 172 | 16 | 17 | .226 | .343 | .397 | .740 | .342 | .171 | .387 | 14.53 | 38.95 | 2.68 | 36.50 | 2016- UDFA -HOU | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 23 | Zach Daniels | 22 | RF-LF | R | 95 | 40 | 146 | 24 | 32 | 8 | 0 | 3 | 18 | 8 | 3 | 23 | 64 | 4 | 0 | 1 | 0 | 5 | 49 | 174 | 11 | 21 | .219 | .339 | .336 | .675 | .308 | .117 | .363 | 13.22 | 36.78 | 2.78 | 48.67 | 2020- 4- 131-HOU | premium | premium | premium | AA | 2018-2025 | 2021 | |
| 2 | Ramiro Rodriguez | 23 | LF-CF | L | 86 | 40 | 132 | 18 | 27 | 6 | 0 | 3 | 15 | 3 | 0 | 14 | 43 | 2 | 0 | 0 | 0 | 2 | 42 | 148 | 9 | 18 | .205 | .291 | .318 | .609 | .242 | .113 | .279 | 9.46 | 29.05 | 3.07 | 44.00 | 2015- UDFA -HOU | premium | premium | premium | AA | 2016-2021 | 2021 | |
| 5 | Cody Orr | 22 | LF-CF | R | 90* | 31 | 111 | 19 | 27 | 5 | 0 | 2 | 9 | 8 | 1 | 8 | 45 | 1 | 1 | 1 | 0 | 1 | 38 | 122 | 7 | 20 | .243 | .298 | .342 | .640 | .234 | .099 | .385 | 6.56 | 36.89 | 5.63 | 55.50 | 2020- UDFA -HOU | premium | premium | premium | A+ | 2018-2022 | 2021 | |
| 5 | Korey Lee | 22 | C | R | 116* | 29 | 109 | 24 | 36 | 5 | 0 | 3 | 14 | 1 | 0 | 12 | 24 | 0 | 0 | 0 | 0 | 0 | 50 | 121 | 8 | 28 | .330 | .397 | .459 | .856 | .248 | .129 | .402 | 9.92 | 19.83 | 2.00 | 36.33 | 2019- 1- 32-HOU | premium | premium | premium | MLB | 2022-2025 | 2017-2025 | 2021 |
| 8 | Luis Guerrero | 22 | LF-RF | R | 93* | 32 | 107 | 17 | 25 | 3 | 0 | 4 | 12 | 2 | 1 | 12 | 34 | 0 | 0 | 0 | 0 | 1 | 40 | 119 | 7 | 18 | .234 | .311 | .374 | .685 | .262 | .140 | .304 | 10.08 | 28.57 | 2.83 | 26.75 | 2019- 8- 256-HOU | premium | premium | premium | AA | 2018-2023 | 2021 | |
| 8 | Joe Perez | 21 | 3B | R | 144* | 25 | 99 | 24 | 35 | 11 | 0 | 8 | 26 | 1 | 1 | 10 | 21 | 0 | 0 | 0 | 0 | 3 | 70 | 109 | 19 | 16 | .354 | .413 | .707 | 1.120 | .455 | .353 | .386 | 9.17 | 19.27 | 2.10 | 12.38 | 2017- 2- 53-HOU | premium | premium | premium | MLB | 2022-2022 | 2018-2025 | 2021 |
| 16 | Yainer Diaz | 22 | C-1B | R | 158* | 25 | 96 | 28 | 38 | 4 | 0 | 11 | 33 | 2 | 0 | 8 | 17 | 0 | 0 | 1 | 0 | 2 | 75 | 105 | 15 | 23 | .396 | .438 | .781 | 1.219 | .490 | .385 | .391 | 7.62 | 16.19 | 2.13 | 8.73 | 2016- UDFA -CLE | premium | premium | premium | MLB | 2022-2025 | 2017-2025 | 2021 |
| 28 | Luke Berryhill | 23 | C-1B | R | 120* | 29 | 94 | 21 | 26 | 10 | 0 | 5 | 19 | 1 | 1 | 10 | 38 | 5 | 0 | 1 | 0 | 4 | 51 | 110 | 15 | 11 | .277 | .373 | .543 | .916 | .372 | .266 | .404 | 9.09 | 34.55 | 3.80 | 18.80 | 2019- 13- 384-CIN | premium | premium | premium | AAA | 2017-2024 | 2021 | |
| 10 | Justin Dirden | 23 | RF-CF | L | 118* | 25 | 83 | 13 | 24 | 3 | 3 | 4 | 17 | 2 | 3 | 12 | 26 | 3 | 0 | 3 | 0 | 1 | 45 | 101 | 10 | 14 | .289 | .386 | .542 | .928 | .386 | .253 | .357 | 11.88 | 25.74 | 2.17 | 20.75 | 2020- UDFA -HOU | premium | premium | premium | AAA | 2016-2024 | 2021 | |
| 11 | Cesar Salazar | 25 | C-1B | L | 102* | 23 | 80 | 10 | 19 | 4 | 0 | 3 | 12 | 2 | 0 | 9 | 23 | 5 | 0 | 2 | 0 | 0 | 32 | 96 | 7 | 12 | .238 | .344 | .400 | .744 | .300 | .162 | .286 | 9.38 | 23.96 | 2.56 | 26.67 | 2018- 7- 222-HOU | premium | premium | premium | MLB | 2023-2025 | 2016-2025 | 2021 |
| 6 | AJ Lee | 24 | SS | R | 63* | 24 | 74 | 10 | 9 | 2 | 0 | 1 | 4 | 3 | 0 | 7 | 43 | 3 | 0 | 1 | 0 | 3 | 14 | 85 | 3 | 6 | .122 | .224 | .189 | .413 | .203 | .067 | .258 | 8.24 | 50.59 | 6.14 | 74.00 | 2019- 34-1036-HOU | premium | premium | premium | AAA | 2016-2022 | 2021 | |
| 8 | Bryan Arias | 24 | 2B-LF | R | 17 | 59 | 9 | 14 | 3 | 0 | 5 | 13 | 1 | 0 | 4 | 20 | 1 | 0 | 0 | 0 | 1 | 32 | 64 | 8 | 6 | .237 | .297 | .542 | .839 | .390 | .305 | .265 | 6.25 | 31.25 | 5.00 | 11.80 | 2019- 28- 856-HOU | premium | premium | premium | AAA | 2016-2024 | 2021 | ||
| 4 | Carlos Machado | 23 | LF-RF | R | 12 | 43 | 5 | 14 | 1 | 0 | 0 | 2 | 1 | 2 | 4 | 9 | 1 | 0 | 0 | 0 | 0 | 15 | 48 | 1 | 13 | .326 | .396 | .349 | .745 | .093 | .023 | .412 | 8.33 | 18.75 | 2.25 | 0.00 | 2014- UDFA -HOU | premium | premium | premium | AAA | 2015-2025 | 2021 | ||
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 90 | Colin Barber | 20 | RF-LF | L | 16 | 42 | 10 | 9 | 1 | 0 | 3 | 7 | 1 | 1 | 9 | 22 | 1 | 0 | 0 | 0 | 0 | 19 | 52 | 4 | 5 | .214 | .365 | .452 | .817 | .452 | .238 | .353 | 17.31 | 42.31 | 2.44 | 14.00 | 2019- 4- 136-HOU | premium | premium | premium | AAA | 2019-2025 | 2021 | ||
| 15 | Tyler Krabbe | 24 | 1B-P | R | 11 | 31 | 4 | 7 | 3 | 0 | 0 | 5 | 0 | 0 | 2 | 10 | 2 | 0 | 0 | 0 | 0 | 10 | 35 | 3 | 4 | .226 | .314 | .323 | .637 | .161 | .097 | .333 | 5.71 | 28.57 | 5.00 | 0.00 | 2019- 19- 586-HOU | premium | premium | premium | AA | 2016-2022 | 2021 | ||
| - | Zach Biermann | 24 | LF-1B | L | 6 | 20 | 2 | 4 | 1 | 0 | 1 | 1 | 0 | 0 | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 8 | 25 | 2 | 2 | .200 | .360 | .400 | .760 | .450 | .200 | .250 | 20.00 | 28.00 | 1.40 | 20.00 | 2019- 23- 706-HOU | premium | premium | premium | AA | 2016-2023 | 2021 | ||
| 27 | Carlos Hurtado | 20 | C | R | 5 | 17 | 3 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 1 | 5 | 20 | 1 | 3 | .235 | .350 | .294 | .644 | .235 | .059 | .308 | 15.00 | 20.00 | 1.33 | 0.00 | 2017- UDFA -HOU | premium | premium | premium | A+ | 2018-2023 | 2021 | ||
| - | Yorbin Ceuta | 21 | 2B | B | 1 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2016- UDFA -HOU | premium | premium | premium | AA | 2017-2021 | 2021 | ||
| Totals: | 1076 | 3896 | 695 | 1020 | 223 | 15 | 186 | 637 | 113 | 46 | 400 | 1304 | 58 | 1 | 29 | 0 | 54 | 1831 | 4384 | 424 | 596 | .262 | .337 | .470 | .807 | .328 | .208 | .343 | 9.12 | 29.74 | 3.26 | 20.95 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 34 | Kyle Serrano | 25 | R | 0 | 0 | 5.63 | 7 | 0 | 0 | 0 | 7 | 4 | 1 | 8.0 | 6 | 5 | 5 | 0 | 7 | 21 | 0 | 1 | 0 | 1.63 | 6.75 | 0.00 | 7.88 | 23.63 | 5.63 | 3.00 | 2017- 10- 301-HOU | premium | premium | premium | AA | 2014-2023 | 2021 | |
| 22 | Cody Deason | 24 | R | 0 | 0 | 5.14 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 7.0 | 9 | 5 | 4 | 1 | 4 | 10 | 0 | 0 | 1 | 1.86 | 11.57 | 1.29 | 5.14 | 12.86 | 6.43 | 2.50 | 2018- 5- 162-HOU | premium | premium | premium | AA | 2016-2023 | 2021 | |
| 19 | Danny Cody | 24 | R | 1 | 6 | 7.27 | 25 | 12 | 0 | 0 | 13 | 5 | 2 | 69.1 | 86 | 62 | 56 | 17 | 44 | 90 | 12 | 0 | 5 | 1.88 | 11.16 | 2.21 | 5.71 | 11.68 | 8.05 | 2.05 | 2019- 17- 526-HOU | premium | premium | premium | A+ | 2016-2022 | 2021 | |
| 10 | Tyler Brown | 22 | R | 3 | 5 | 7.25 | 15 | 11 | 0 | 0 | 4 | 2 | 0 | 63.1 | 71 | 52 | 51 | 14 | 32 | 68 | 1 | 0 | 4 | 1.63 | 10.09 | 1.99 | 4.55 | 9.66 | 7.39 | 2.13 | 2020- 3- 101-HOU | premium | premium | premium | AAA | 2018-2023 | 2021 | |
| 36 | R.J. Freure | 23 | R | 3 | 5 | 6.31 | 17 | 9 | 0 | 0 | 8 | 1 | 0 | 61.1 | 54 | 46 | 43 | 14 | 38 | 88 | 6 | 0 | 1 | 1.50 | 7.92 | 2.05 | 5.58 | 12.91 | 6.75 | 2.32 | 2018- 6- 192-HOU | premium | premium | premium | AA | 2017-2023 | 2021 | |
| 17 | Matt Ruppenthal | 25 | R | 4 | 2 | 5.34 | 15 | 9 | 0 | 0 | 6 | 3 | 1 | 60.2 | 60 | 37 | 36 | 7 | 28 | 71 | 7 | 3 | 6 | 1.45 | 8.90 | 1.04 | 4.15 | 10.53 | 5.49 | 2.54 | 2017- 17- 511-HOU | premium | premium | premium | AAA | 2015-2023 | 2021 | |
| 40 | Derek West | 24 | R | 0 | 0 | 9.45 | 6 | 0 | 0 | 0 | 6 | 4 | 1 | 6.2 | 7 | 7 | 7 | 3 | 9 | 9 | 1 | 0 | 0 | 2.40 | 9.45 | 4.05 | 12.15 | 12.15 | 9.45 | 1.00 | 2019- 14- 436-HOU | premium | premium | premium | AA | 2018-2025 | 2021 | |
| 13 | Daniel Procopio | 25 | R | 0 | 0 | 17.05 | 8 | 0 | 0 | 0 | 8 | 2 | 0 | 6.1 | 13 | 15 | 12 | 1 | 13 | 7 | 1 | 0 | 1 | 4.11 | 18.47 | 1.42 | 18.47 | 9.95 | 21.32 | 0.54 | 2017- 10- 295-ANA | premium | premium | premium | AA | 2014-2021 | 2021 | |
| 34 | Ray Gaither | 23 | R | 2 | 1 | 6.00 | 5 | 0 | 0 | 0 | 5 | 3 | 1 | 6.0 | 8 | 5 | 4 | 1 | 2 | 3 | 1 | 0 | 0 | 1.67 | 12.00 | 1.50 | 3.00 | 4.50 | 7.50 | 1.50 | 2021- UDFA -HOU | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 16 | Jose Bravo | 24 | R | 2 | 5 | 5.37 | 14 | 6 | 0 | 0 | 8 | 4 | 1 | 57.0 | 65 | 36 | 34 | 14 | 14 | 72 | 1 | 1 | 3 | 1.39 | 10.26 | 2.21 | 2.21 | 11.37 | 5.68 | 5.14 | 2016- UDFA -HOU | premium | premium | premium | AAA | 2016-2025 | 2021 | |
| 18 | Juan Pablo Lopez | 22 | L | 6 | 3 | 6.71 | 16 | 8 | 0 | 0 | 8 | 3 | 1 | 56.1 | 60 | 48 | 42 | 9 | 32 | 65 | 8 | 0 | 4 | 1.63 | 9.59 | 1.44 | 5.11 | 10.38 | 7.67 | 2.03 | 2016- UDFA -HOU | premium | premium | premium | A+ | 2017-2022 | 2021 | |
| 32 | Chandler Casey | 25 | R | 4 | 2 | 5.60 | 27 | 1 | 0 | 0 | 26 | 13 | 3 | 53.0 | 66 | 39 | 33 | 11 | 11 | 35 | 3 | 0 | 4 | 1.45 | 11.21 | 1.87 | 1.87 | 5.94 | 6.62 | 3.18 | 2019- 26- 796-HOU | premium | premium | premium | AA | 2016-2023 | 2021 | |
| 4 | Alfredi Jimenez | 21 | R | 3 | 4 | 4.80 | 9 | 7 | 0 | 0 | 2 | 1 | 0 | 45.0 | 52 | 28 | 24 | 4 | 10 | 41 | 3 | 1 | 6 | 1.38 | 10.40 | 0.80 | 2.00 | 8.20 | 5.60 | 4.10 | 2017- UDFA -HOU | premium | premium | premium | A+ | 2018-2022 | 2021 | |
| 29 | Mark Moclair | 24 | R | 1 | 1 | 5.48 | 22 | 4 | 0 | 0 | 18 | 6 | 4 | 42.2 | 31 | 29 | 26 | 4 | 50 | 55 | 5 | 1 | 8 | 1.90 | 6.54 | 0.84 | 10.55 | 11.60 | 6.12 | 1.10 | 2018- 12- 372-HOU | premium | premium | premium | AA | 2016-2024 | 2021 | |
| 21 | Misael Tamarez | 21 | R | 2 | 1 | 3.48 | 7 | 7 | 0 | 0 | 0 | 0 | 0 | 33.2 | 30 | 15 | 13 | 4 | 10 | 39 | 2 | 0 | 0 | 1.19 | 8.02 | 1.07 | 2.67 | 10.43 | 4.01 | 3.90 | 2019- UDFA -HOU | premium | premium | premium | AAA | 2019-2025 | 2021 | |
| 5 | Julio Robaina | 20 | L | 3 | 2 | 3.90 | 6 | 5 | 0 | 0 | 1 | 1 | 0 | 32.1 | 32 | 17 | 14 | 3 | 7 | 42 | 0 | 0 | 0 | 1.21 | 8.91 | 0.84 | 1.95 | 11.69 | 4.73 | 6.00 | 2017- UDFA -HOU | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 9 | Jaime Melendez | 19 | R | 2 | 3 | 4.78 | 11 | 7 | 0 | 0 | 4 | 0 | 0 | 32.0 | 34 | 19 | 17 | 2 | 24 | 41 | 3 | 0 | 2 | 1.81 | 9.56 | 0.56 | 6.75 | 11.53 | 5.34 | 1.71 | 2019- UDFA -HOU | premium | premium | premium | AA | 2019-2024 | 2021 | |
| 13 | Layne Henderson | 25 | R | 0 | 0 | 0.00 | 3 | 0 | 0 | 0 | 3 | 3 | 0 | 3.1 | 1 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0.30 | 2.70 | 0.00 | 0.00 | 16.20 | 0.00 | 0.00 | 2018- 30- 912-HOU | premium | premium | premium | AAA | 2018-2024 | 2021 | |
| 22 | Jimmy Endersby | 23 | R | 2 | 1 | 4.85 | 8 | 4 | 0 | 0 | 4 | 3 | 1 | 29.2 | 29 | 17 | 16 | 3 | 13 | 43 | 9 | 0 | 0 | 1.42 | 8.80 | 0.91 | 3.94 | 13.04 | 5.16 | 3.31 | 2020- UDFA -HOU | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 22 | Brayan De Paula | 22 | L | 0 | 3 | 6.67 | 10 | 5 | 0 | 0 | 5 | 3 | 0 | 28.1 | 36 | 24 | 21 | 6 | 18 | 34 | 5 | 1 | 8 | 1.91 | 11.44 | 1.91 | 5.72 | 10.80 | 7.62 | 1.89 | 2017- UDFA -MIA | premium | premium | premium | AA | 2017-2024 | 2021 | |
| 27 | Angel Macuare | 21 | R | 0 | 5 | 9.95 | 8 | 5 | 0 | 0 | 3 | 1 | 0 | 25.1 | 34 | 30 | 28 | 6 | 13 | 32 | 1 | 0 | 1 | 1.86 | 12.08 | 2.13 | 4.62 | 11.37 | 10.66 | 2.46 | 2016- UDFA -HOU | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 26 | Michael Horrell | 24 | R | 0 | 0 | 2.16 | 15 | 0 | 0 | 0 | 15 | 5 | 2 | 25.0 | 27 | 16 | 6 | 1 | 12 | 27 | 4 | 0 | 3 | 1.56 | 9.72 | 0.36 | 4.32 | 9.72 | 5.76 | 2.25 | 2019- 30- 916-HOU | premium | premium | premium | AA | 2016-2025 | 2021 | |
| 33 | Tommy DeJuneas | 25 | R | 2 | 1 | 4.76 | 14 | 0 | 0 | 0 | 14 | 10 | 2 | 22.2 | 23 | 15 | 12 | 4 | 14 | 24 | 2 | 0 | 2 | 1.63 | 9.13 | 1.59 | 5.56 | 9.53 | 5.96 | 1.71 | 2017- 26- 792-CLE | premium | premium | premium | AA | 2015-2022 | 2021 | |
| 34 | Jonathan Sprinkle | 22 | R | 1 | 2 | 5.96 | 16 | 0 | 0 | 0 | 16 | 9 | 0 | 22.2 | 13 | 15 | 15 | 3 | 15 | 45 | 12 | 0 | 2 | 1.24 | 5.16 | 1.19 | 5.96 | 17.87 | 5.96 | 3.00 | 2020- UDFA -HOU | premium | premium | premium | AA | 2018-2024 | 2021 | |
| 21 | Yeremi Ceballos | 22 | L | 2 | 2 | 8.74 | 19 | 1 | 0 | 0 | 18 | 5 | 1 | 22.2 | 25 | 35 | 22 | 5 | 31 | 31 | 15 | 0 | 5 | 2.47 | 9.93 | 1.99 | 12.31 | 12.31 | 13.90 | 1.00 | 2016- UDFA -HOU | premium | premium | premium | A+ | 2016-2022 | 2021 | |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 8 | Bryan Arias | 24 | R | 0 | 0 | 7.71 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 2.1 | 4 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 1.71 | 15.43 | 0.00 | 0.00 | 0.00 | 7.71 | 0.00 | 2019- 28- 856-HOU | premium | premium | premium | AAA | 2016-2024 | 2021 | |
| 15 | Tyler Krabbe | 24 | R | 0 | 0 | 3.86 | 3 | 0 | 0 | 0 | 3 | 3 | 0 | 2.1 | 2 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0.86 | 7.71 | 3.86 | 0.00 | 3.86 | 3.86 | 0.00 | 2019- 19- 586-HOU | premium | premium | premium | AA | 2016-2022 | 2021 | |
| 14 | Alex Holderbach | 24 | R | 0 | 0 | 4.50 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 2.0 | 2 | 1 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 1.50 | 9.00 | 0.00 | 4.50 | 9.00 | 4.50 | 2.00 | 2018- 16- 492-HOU | premium | premium | premium | AA | 2016-2022 | 2021 | |
| 12 | Kevin Holcomb | 22 | R | 3 | 0 | 5.68 | 9 | 0 | 0 | 0 | 9 | 1 | 0 | 19.0 | 19 | 14 | 12 | 3 | 9 | 17 | 1 | 0 | 1 | 1.47 | 9.00 | 1.42 | 4.26 | 8.05 | 6.63 | 1.89 | 2019- 13- 406-HOU | premium | premium | premium | A+ | 2018-2022 | 2021 | |
| 1 | Devin Conn | 24 | R | 1 | 1 | 4.91 | 13 | 0 | 0 | 0 | 13 | 6 | 1 | 18.1 | 13 | 11 | 10 | 5 | 7 | 22 | 1 | 0 | 2 | 1.09 | 6.38 | 2.45 | 3.44 | 10.80 | 5.40 | 3.14 | 2018- 19- 582-HOU | premium | premium | premium | AAA | 2017-2023 | 2021 | |
| 38 | Diosmerky Taveras | 21 | R | 3 | 0 | 1.53 | 4 | 2 | 0 | 0 | 2 | 0 | 0 | 17.2 | 9 | 3 | 3 | 2 | 6 | 23 | 2 | 0 | 0 | 0.85 | 4.58 | 1.02 | 3.06 | 11.72 | 1.53 | 3.83 | 2017- UDFA -HOU | premium | premium | premium | AA | 2017-2024 | 2021 | |
| 13 | Cesar Gomez | 22 | R | 1 | 1 | 1.62 | 4 | 2 | 0 | 0 | 2 | 1 | 0 | 16.2 | 22 | 12 | 3 | 0 | 3 | 14 | 0 | 1 | 2 | 1.50 | 11.88 | 0.00 | 1.62 | 7.56 | 6.48 | 4.67 | 2020- UDFA -HOU | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 37 | Blair Henley | 24 | R | 0 | 2 | 7.02 | 5 | 3 | 0 | 0 | 2 | 1 | 0 | 16.2 | 26 | 15 | 13 | 3 | 9 | 23 | 0 | 2 | 3 | 2.10 | 14.04 | 1.62 | 4.86 | 12.42 | 8.10 | 2.56 | 2019- 7- 226-HOU | premium | premium | premium | MLB | 2024-2024 | 2017-2025 | 2021 |
| 17 | Ernesto Jaquez | 22 | R | 1 | 2 | 5.94 | 8 | 0 | 0 | 0 | 8 | 2 | 1 | 16.2 | 20 | 13 | 11 | 4 | 8 | 23 | 0 | 0 | 1 | 1.68 | 10.80 | 2.16 | 4.32 | 12.42 | 7.02 | 2.88 | 2017- UDFA -HOU | premium | premium | premium | A+ | 2017-2024 | 2021 | |
| 26 | Kyle Gruller | 23 | R | 0 | 0 | 6.06 | 6 | 4 | 0 | 0 | 2 | 0 | 0 | 16.1 | 9 | 13 | 11 | 3 | 17 | 16 | 3 | 1 | 2 | 1.59 | 4.96 | 1.65 | 9.37 | 8.82 | 7.16 | 0.94 | 2020- UDFA -HOU | premium | premium | premium | A+ | 2017-2022 | 2021 | |
| 6 | Freylin Garcia | 23 | R | 0 | 1 | 2.35 | 9 | 0 | 0 | 0 | 9 | 4 | 0 | 15.1 | 10 | 5 | 4 | 1 | 9 | 18 | 6 | 3 | 0 | 1.24 | 5.87 | 0.59 | 5.28 | 10.57 | 2.93 | 2.00 | 2016- UDFA -HOU | premium | premium | premium | AA | 2016-2024 | 2021 | |
| 27 | Felipe Tejada | 23 | R | 2 | 0 | 1.23 | 8 | 0 | 0 | 0 | 8 | 2 | 0 | 14.2 | 9 | 2 | 2 | 1 | 6 | 22 | 1 | 1 | 0 | 1.02 | 5.52 | 0.61 | 3.68 | 13.50 | 1.23 | 3.67 | 2014- UDFA -HOU | premium | premium | premium | AA | 2015-2022 | 2021 | |
| 28 | Jose Alberto Rivera | 24 | R | 0 | 1 | 7.94 | 5 | 3 | 0 | 0 | 2 | 0 | 0 | 11.1 | 10 | 12 | 10 | 2 | 9 | 17 | 0 | 0 | 1 | 1.68 | 7.94 | 1.59 | 7.15 | 13.50 | 9.53 | 1.89 | 2016- UDFA -HOU | premium | premium | premium | A+ | 2017-2021 | 2021 | |
| 1 | Deury Carrasco | 21 | R | 0 | 0 | 18.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 1 | 2 | 2 | 0 | 3 | 0 | 0 | 0 | 1 | 4.00 | 9.00 | 0.00 | 27.00 | 0.00 | 18.00 | 0.00 | 2016- UDFA -HOU | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 39 | Cole McDonald | 24 | R | 0 | 0 | 0.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 2.00 | 0.00 | 0.00 | 18.00 | 9.00 | 0.00 | 0.50 | 2019- 15- 466-HOU | premium | premium | premium | AAA | 2016-2024 | 2021 | |
| Totals: | 54 | 62 | 5.68 | 385 | 116 | 0 | 0 | 116 | 269 | 23 | 991.2 | 1028 | 723 | 626 | 162 | 540 | 1198 | 116 | 16 | 80 | 1.58 | 9.33 | 1.47 | 4.90 | 10.87 | 6.56 | 2.22 | premium | premium | premium |