| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 22 | David Fletcher | 27 | 2B | R | 87 | 157 | 626 | 74 | 164 | 27 | 3 | 2 | 47 | 15 | 3 | 31 | 60 | 1 | 6 | 1 | 1 | 10 | 203 | 665 | 32 | 132 | .262 | .297 | .324 | .621 | .131 | .062 | .287 | 4.66 | 9.02 | 1.94 | 313.00 | 2015- 6- 195-ANA | premium | premium | premium | MLB | 2018-2024 | 2014-2025 | 2021 |
| 17 | Shohei Ohtani | 26 | DH | L | 126 | 155 | 537 | 103 | 138 | 26 | 8 | 46 | 100 | 26 | 10 | 96 | 189 | 4 | 0 | 2 | 20 | 7 | 318 | 639 | 80 | 58 | .257 | .372 | .592 | .964 | .544 | .335 | .303 | 15.02 | 29.58 | 1.97 | 11.67 | 2017- UDFA -ANA | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 20 | Jared Walsh | 27 | 1B | L | 114 | 144 | 530 | 70 | 147 | 34 | 1 | 29 | 98 | 2 | 1 | 48 | 152 | 4 | 0 | 3 | 6 | 7 | 270 | 585 | 64 | 83 | .277 | .340 | .509 | .849 | .325 | .232 | .335 | 8.21 | 25.98 | 3.17 | 18.28 | 2015- 39-1185-ANA | premium | premium | premium | MLB | 2019-2024 | 2012-2024 | 2021 |
| 12 | Jose Iglesias | 31 | SS | R | 96 | 114 | 424 | 57 | 110 | 23 | 1 | 8 | 41 | 5 | 2 | 18 | 66 | 4 | 0 | 1 | 0 | 10 | 159 | 447 | 32 | 78 | .259 | .295 | .375 | .670 | .165 | .116 | .291 | 4.03 | 14.77 | 3.67 | 53.00 | 2009- UDFA -BOS | premium | premium | premium | MLB | 2011-2025 | 2010-2025 | 2021 |
| 13 | Phil Gosselin | 32 | LF-3B | R | 94 | 104 | 345 | 40 | 90 | 14 | 0 | 7 | 47 | 4 | 2 | 24 | 81 | 3 | 0 | 1 | 0 | 3 | 125 | 373 | 21 | 69 | .261 | .314 | .362 | .676 | .177 | .101 | .322 | 6.43 | 21.72 | 3.38 | 49.29 | 2010- 5- 164-ATL | premium | premium | premium | MLB | 2013-2022 | 2008-2022 | 2021 |
| 10 | Justin Upton | 33 | LF | R | 97 | 89 | 318 | 47 | 67 | 12 | 0 | 17 | 41 | 4 | 1 | 39 | 107 | 1 | 0 | 3 | 0 | 11 | 130 | 361 | 29 | 38 | .211 | .296 | .409 | .705 | .330 | .198 | .254 | 10.80 | 29.64 | 2.74 | 18.71 | 2005- 1- 1-ARI | premium | premium | premium | MLB | 2007-2022 | 2006-2022 | 2021 |
| 19 | Juan Lagares | 32 | CF-RF | R | 86 | 112 | 309 | 39 | 73 | 20 | 2 | 6 | 38 | 1 | 2 | 12 | 76 | 1 | 4 | 1 | 0 | 8 | 115 | 327 | 28 | 45 | .236 | .266 | .372 | .638 | .172 | .136 | .294 | 3.67 | 23.24 | 6.33 | 51.50 | 2006- UDFA -NYN | premium | premium | premium | MLB | 2013-2022 | 2007-2022 | 2021 |
| 33 | Max Stassi | 30 | C | R | 104 | 87 | 282 | 45 | 68 | 11 | 1 | 13 | 35 | 0 | 0 | 28 | 101 | 8 | 0 | 1 | 0 | 8 | 120 | 319 | 25 | 43 | .241 | .326 | .426 | .752 | .284 | .185 | .325 | 8.78 | 31.66 | 3.61 | 21.69 | 2009- 4- 123-OAK | premium | premium | premium | MLB | 2013-2022 | 2009-2025 | 2021 |
| 16 | Brandon Marsh | 23 | CF | L | 95 | 70 | 236 | 27 | 60 | 12 | 3 | 2 | 19 | 6 | 1 | 20 | 91 | 2 | 1 | 1 | 0 | 3 | 84 | 260 | 17 | 43 | .254 | .317 | .356 | .673 | .208 | .102 | .403 | 7.69 | 35.00 | 4.55 | 118.00 | 2016- 2- 60-ANA | premium | premium | premium | MLB | 2021-2025 | 2017-2025 | 2021 |
| 8 | Jack Mayfield | 30 | 3B | R | 91 | 75 | 232 | 28 | 52 | 14 | 0 | 10 | 36 | 5 | 0 | 16 | 58 | 3 | 3 | 1 | 0 | 4 | 96 | 255 | 24 | 28 | .224 | .282 | .414 | .696 | .280 | .190 | .255 | 6.27 | 22.75 | 3.63 | 23.20 | 2013- UDFA -HOU | premium | premium | premium | MLB | 2019-2022 | 2010-2025 | 2021 |
| 24 | Kurt Suzuki | 37 | C | R | 89 | 72 | 219 | 17 | 49 | 8 | 0 | 6 | 16 | 0 | 0 | 12 | 44 | 11 | 2 | 3 | 0 | 7 | 75 | 247 | 14 | 35 | .224 | .294 | .342 | .636 | .174 | .118 | .250 | 4.86 | 17.81 | 3.67 | 36.50 | 2004- 2- 67-OAK | premium | premium | premium | MLB | 2007-2022 | 2002-2022 | 2021 |
| 6 | Anthony Rendon | 31 | 3B | R | 98 | 58 | 217 | 24 | 52 | 13 | 0 | 6 | 34 | 0 | 0 | 29 | 41 | 1 | 0 | 2 | 2 | 11 | 83 | 249 | 19 | 33 | .240 | .329 | .382 | .711 | .276 | .142 | .267 | 11.65 | 16.47 | 1.41 | 36.17 | 2011- 1- 6-WAS | premium | premium | premium | MLB | 2013-2024 | 2009-2024 | 2021 |
| 61 | Taylor Ward | 27 | RF | R | 105 | 65 | 208 | 33 | 52 | 15 | 0 | 8 | 33 | 1 | 1 | 20 | 55 | 6 | 2 | 1 | 0 | 4 | 91 | 237 | 23 | 29 | .250 | .332 | .438 | .770 | .284 | .188 | .301 | 8.44 | 23.21 | 2.75 | 26.00 | 2015- 1- 26-ANA | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 2 | Luis Rengifo | 24 | SS-RF | B | 78* | 54 | 174 | 22 | 35 | 1 | 0 | 6 | 18 | 1 | 0 | 9 | 38 | 2 | 3 | 2 | 0 | 3 | 54 | 190 | 7 | 28 | .201 | .246 | .310 | .556 | .167 | .109 | .220 | 4.74 | 20.00 | 4.22 | 29.00 | 2014- UDFA -SEA | premium | premium | premium | MLB | 2019-2025 | 2015-2025 | 2021 |
| 18 | Jose Rojas | 28 | RF-2B | L | 93* | 61 | 168 | 26 | 35 | 14 | 0 | 6 | 15 | 2 | 1 | 15 | 50 | 1 | 0 | 0 | 0 | 2 | 67 | 184 | 20 | 15 | .208 | .277 | .399 | .676 | .286 | .191 | .259 | 8.15 | 27.17 | 3.33 | 28.00 | 2016- 36-1086-ANA | premium | premium | premium | MLB | 2021-2022 | 2013-2025 | 2021 |
| 7 | Jo Adell | 22 | LF-RF | R | 96* | 35 | 130 | 17 | 32 | 5 | 2 | 4 | 26 | 2 | 1 | 8 | 32 | 1 | 1 | 0 | 0 | 3 | 53 | 140 | 11 | 21 | .246 | .295 | .408 | .703 | .231 | .162 | .298 | 5.71 | 22.86 | 4.00 | 32.50 | 2017- 1- 10-ANA | premium | premium | premium | MLB | 2020-2025 | 2017-2025 | 2021 |
| 27 | Mike Trout | 29 | CF | R | 144* | 36 | 117 | 23 | 39 | 8 | 1 | 8 | 18 | 2 | 0 | 27 | 41 | 2 | 0 | 0 | 5 | 0 | 73 | 146 | 17 | 22 | .333 | .466 | .624 | 1.090 | .538 | .291 | .456 | 18.49 | 28.08 | 1.52 | 14.63 | 2009- 1- 25-ANA | premium | premium | premium | MLB | 2011-2025 | 2009-2025 | 2021 |
| 55 | Albert Pujols | 41 | 1B | R | 97 | 24 | 86 | 9 | 17 | 0 | 0 | 5 | 12 | 1 | 0 | 3 | 13 | 3 | 0 | 0 | 1 | 4 | 32 | 92 | 5 | 12 | .198 | .250 | .372 | .622 | .221 | .174 | .176 | 3.26 | 14.13 | 4.33 | 17.20 | 1999- 13- 402-SLN | premium | premium | premium | MLB | 2001-2022 | 2000-2022 | 2021 |
| 12 | Adam Eaton | 32 | RF | L | 86 | 25 | 65 | 5 | 13 | 2 | 0 | 1 | 2 | 1 | 0 | 2 | 16 | 1 | 0 | 1 | 0 | 1 | 18 | 69 | 3 | 10 | .200 | .232 | .277 | .509 | .123 | .077 | .245 | 2.90 | 23.19 | 8.00 | 65.00 | 2010- 19- 571-ARI | premium | premium | premium | MLB | 2012-2021 | 2008-2021 | 2021 |
| 8 | Kean Wong | 26 | 2B-3B | L | 32 | 60 | 3 | 10 | 2 | 1 | 0 | 6 | 0 | 1 | 2 | 17 | 0 | 4 | 0 | 0 | 0 | 14 | 66 | 3 | 7 | .167 | .194 | .233 | .427 | .083 | .066 | .233 | 3.03 | 25.76 | 8.50 | 0.00 | 2013- 4- 128-TBA | premium | premium | premium | MLB | 2019-2021 | 2013-2023 | 2021 | |
| 44 | Scott Schebler | 30 | RF-CF | L | 14 | 34 | 3 | 5 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 17 | 0 | 0 | 0 | 0 | 0 | 8 | 34 | 3 | 2 | .147 | .147 | .235 | .382 | .088 | .088 | .294 | 0.00 | 50.00 | 0.00 | 0.00 | 2010- 26- 802-LAN | premium | premium | premium | MLB | 2015-2021 | 2010-2022 | 2021 | |
| 16 | Drew Butera | 37 | C | R | 12 | 32 | 1 | 3 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | 16 | 0 | 3 | 1 | 0 | 0 | 4 | 36 | 1 | 2 | .094 | .091 | .125 | .216 | .031 | .031 | .176 | 0.00 | 44.44 | 0.00 | 0.00 | 2005- 5- 149-NYN | premium | premium | premium | MLB | 2010-2021 | 2003-2021 | 2021 | |
| 12 | Anthony Bemboom | 31 | C | L | 8 | 27 | 2 | 6 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 10 | 0 | 0 | 0 | 0 | 1 | 6 | 28 | 0 | 6 | .222 | .250 | .222 | .472 | .037 | .000 | .353 | 3.57 | 35.71 | 10.00 | 0.00 | 2012- 22- 687-ANA | premium | premium | premium | MLB | 2019-2023 | 2010-2024 | 2021 | |
| 25 | Dexter Fowler | 35 | RF | B | 7 | 20 | 3 | 5 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 5 | 21 | 0 | 5 | .250 | .286 | .250 | .536 | .100 | .000 | .357 | 4.76 | 28.57 | 6.00 | 0.00 | 2004- 14- 410-COL | premium | premium | premium | MLB | 2008-2021 | 2005-2022 | 2021 | |
| 9 | Jon Jay | 36 | LF | L | 5 | 14 | 2 | 5 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5 | 14 | 0 | 5 | .357 | .357 | .357 | .714 | .000 | .000 | .417 | 0.00 | 14.29 | 0.00 | 0.00 | 2006- 2- 74-SLN | premium | premium | premium | MLB | 2010-2021 | 2004-2021 | 2021 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 23 | Matt Thaiss | 26 | 1B | L | 3 | 7 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 8 | 0 | 1 | .143 | .250 | .143 | .393 | .143 | .000 | .167 | 12.50 | 12.50 | 1.00 | 0.00 | 2016- 1- 16-ANA | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 | |
| 43 | Patrick Sandoval | 24 | P | L | 2 | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .250 | .250 | .250 | .500 | .000 | .000 | .500 | 0.00 | 50.00 | 0.00 | 0.00 | 2015- 11- 319-HOU | premium | premium | premium | MLB | 2019-2024 | 2015-2024 | 2021 | |
| 37 | Dylan Bundy | 28 | P | B | 3 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .250 | .250 | .250 | .500 | .000 | .000 | 1.000 | 0.00 | 75.00 | 0.00 | 0.00 | 2011- 1- 4-BAL | premium | premium | premium | MLB | 2012-2022 | 2012-2023 | 2021 | |
| 51 | Jaime Barria | 24 | P | R | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2013- UDFA -ANA | premium | premium | premium | MLB | 2018-2023 | 2013-2025 | 2021 | |
| 28 | Andrew Heaney | 30 | P | L | 1 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 1 | .500 | .667 | .500 | 1.167 | .500 | .000 | 1.000 | 33.33 | 33.33 | 1.00 | 0.00 | 2012- 1- 9-MIA | premium | premium | premium | MLB | 2014-2025 | 2010-2025 | 2021 | |
| 41 | Junior Guerra | 36 | P | R | 5 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2014- UDFA -ATL | premium | premium | premium | MLB | 2015-2021 | 2003-2025 | 2021 | |
| 56 | Tony Watson | 36 | P | L | 9 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2007- 9- 278-PIT | premium | premium | premium | MLB | 2011-2021 | 2004-2021 | 2021 | |
| 54 | Jose Suarez | 23 | P | L | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2014- UDFA -ANA | premium | premium | premium | MLB | 2019-2025 | 2015-2025 | 2021 | |
| 58 | Packy Naughton | 25 | P | R | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2017- 9- 257-CIN | premium | premium | premium | MLB | 2021-2023 | 2015-2024 | 2021 | |
| 38 | Alex Cobb | 33 | P | R | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2006- 4- 109-TBA | premium | premium | premium | MLB | 2011-2024 | 2006-2025 | 2021 | |
| 48 | Reid Detmers | 21 | P | L | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .500 | .000 | .500 | 1.000 | .000 | .000 | 50.00 | 50.00 | 1.00 | 0.00 | 2020- 1- 10-ANA | premium | premium | premium | MLB | 2021-2025 | 2018-2025 | 2021 | |
| 47 | Griffin Canning | 25 | P | R | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2017- 2- 47-ANA | premium | premium | premium | MLB | 2019-2025 | 2015-2025 | 2021 | |
| Totals: | 1646 | 5437 | 723 | 1331 | 265 | 23 | 190 | 691 | 79 | 26 | 464 | 1394 | 59 | 30 | 25 | 35 | 107 | 2212 | 6015 | 478 | 853 | .245 | .310 | .407 | .717 | .257 | .162 | .294 | 7.71 | 23.18 | 3.00 | 28.62 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 54 | Jose Suarez | 23 | L | 8 | 8 | 3.75 | 23 | 14 | 1 | 0 | 9 | 2 | 0 | 98.1 | 85 | 45 | 41 | 11 | 36 | 85 | 4 | 1 | 4 | 1.23 | 7.78 | 1.01 | 3.29 | 7.78 | 4.12 | 2.36 | 2014- UDFA -ANA | premium | premium | premium | MLB | 2019-2025 | 2015-2025 | 2021 |
| 28 | Andrew Heaney | 30 | L | 6 | 7 | 5.27 | 18 | 18 | 0 | 0 | 0 | 0 | 0 | 94.0 | 92 | 56 | 55 | 16 | 31 | 113 | 3 | 0 | 3 | 1.31 | 8.81 | 1.53 | 2.97 | 10.82 | 5.36 | 3.65 | 2012- 1- 9-MIA | premium | premium | premium | MLB | 2014-2025 | 2010-2025 | 2021 |
| 38 | Alex Cobb | 33 | R | 8 | 3 | 3.76 | 18 | 18 | 0 | 0 | 0 | 0 | 0 | 93.1 | 85 | 46 | 39 | 5 | 33 | 98 | 4 | 0 | 3 | 1.26 | 8.20 | 0.48 | 3.18 | 9.45 | 4.44 | 2.97 | 2006- 4- 109-TBA | premium | premium | premium | MLB | 2011-2024 | 2006-2025 | 2021 |
| 37 | Dylan Bundy | 28 | R | 2 | 9 | 6.06 | 23 | 19 | 0 | 0 | 4 | 1 | 0 | 90.2 | 89 | 64 | 61 | 20 | 34 | 84 | 1 | 0 | 6 | 1.36 | 8.83 | 1.99 | 3.37 | 8.34 | 6.35 | 2.47 | 2011- 1- 4-BAL | premium | premium | premium | MLB | 2012-2022 | 2012-2023 | 2021 |
| 62 | Oliver Ortega | 24 | R | 1 | 0 | 4.82 | 8 | 0 | 0 | 0 | 8 | 1 | 0 | 9.1 | 12 | 5 | 5 | 1 | 2 | 4 | 0 | 1 | 1 | 1.50 | 11.57 | 0.96 | 1.93 | 3.86 | 4.82 | 2.00 | 2015- UDFA -ANA | premium | premium | premium | MLB | 2021-2023 | 2015-2025 | 2021 |
| 43 | Patrick Sandoval | 24 | L | 3 | 6 | 3.62 | 17 | 14 | 0 | 0 | 3 | 2 | 1 | 87.0 | 69 | 38 | 35 | 11 | 36 | 94 | 3 | 0 | 4 | 1.21 | 7.14 | 1.14 | 3.72 | 9.72 | 3.93 | 2.61 | 2015- 11- 319-HOU | premium | premium | premium | MLB | 2019-2024 | 2015-2024 | 2021 |
| 49 | James Hoyt | 34 | R | 0 | 0 | 6.75 | 9 | 0 | 0 | 0 | 9 | 3 | 0 | 8.0 | 12 | 10 | 6 | 0 | 7 | 11 | 0 | 0 | 2 | 2.38 | 13.50 | 0.00 | 7.88 | 12.38 | 11.25 | 1.57 | 2012- UDFA -ATL | premium | premium | premium | MLB | 2016-2021 | 2010-2025 | 2021 |
| 21 | Mike Mayers | 29 | R | 5 | 5 | 3.84 | 72 | 2 | 0 | 0 | 70 | 9 | 2 | 75.0 | 71 | 32 | 32 | 11 | 26 | 90 | 0 | 0 | 3 | 1.29 | 8.52 | 1.32 | 3.12 | 10.80 | 3.84 | 3.46 | 2013- 3- 93-SLN | premium | premium | premium | MLB | 2016-2023 | 2011-2024 | 2021 |
| 32 | Raisel Iglesias | 31 | R | 7 | 5 | 2.57 | 65 | 0 | 0 | 0 | 65 | 59 | 34 | 70.0 | 53 | 25 | 20 | 11 | 12 | 103 | 2 | 1 | 1 | 0.93 | 6.81 | 1.41 | 1.54 | 13.24 | 3.21 | 8.58 | 2014- UDFA -CIN | premium | premium | premium | MLB | 2015-2025 | 2015-2025 | 2021 |
| 40 | Steve Cishek | 35 | R | 0 | 2 | 3.42 | 74 | 0 | 0 | 0 | 74 | 9 | 0 | 68.1 | 61 | 32 | 26 | 2 | 41 | 64 | 4 | 2 | 6 | 1.49 | 8.03 | 0.26 | 5.40 | 8.43 | 4.21 | 1.56 | 2007- 5- 166-MIA | premium | premium | premium | MLB | 2010-2022 | 2007-2022 | 2021 |
| 41 | Junior Guerra | 36 | R | 5 | 2 | 6.06 | 41 | 1 | 0 | 0 | 40 | 14 | 0 | 65.1 | 67 | 45 | 44 | 6 | 46 | 61 | 9 | 2 | 3 | 1.73 | 9.23 | 0.83 | 6.34 | 8.40 | 6.20 | 1.33 | 2014- UDFA -ATL | premium | premium | premium | MLB | 2015-2021 | 2003-2025 | 2021 |
| 47 | Griffin Canning | 25 | R | 5 | 4 | 5.60 | 14 | 13 | 0 | 0 | 1 | 0 | 0 | 62.2 | 65 | 41 | 39 | 14 | 28 | 62 | 3 | 0 | 1 | 1.48 | 9.34 | 2.01 | 4.02 | 8.90 | 5.89 | 2.21 | 2017- 2- 47-ANA | premium | premium | premium | MLB | 2019-2025 | 2015-2025 | 2021 |
| 60 | Hunter Strickland | 32 | R | 0 | 0 | 9.95 | 9 | 0 | 0 | 0 | 9 | 2 | 0 | 6.1 | 11 | 9 | 7 | 3 | 4 | 4 | 0 | 0 | 0 | 2.37 | 15.63 | 4.26 | 5.68 | 5.68 | 12.79 | 1.00 | 2007- 18- 564-BOS | premium | premium | premium | MLB | 2014-2025 | 2007-2025 | 2021 |
| 52 | Jake Petricka | 33 | R | 0 | 1 | 15.00 | 7 | 0 | 0 | 0 | 7 | 1 | 0 | 6.0 | 6 | 10 | 10 | 1 | 7 | 8 | 1 | 0 | 1 | 2.17 | 9.00 | 1.50 | 10.50 | 12.00 | 15.00 | 1.14 | 2010- 2- 63-CHA | premium | premium | premium | MLB | 2013-2021 | 2009-2022 | 2021 |
| 51 | Jaime Barria | 24 | R | 2 | 4 | 4.61 | 13 | 11 | 0 | 0 | 2 | 0 | 0 | 56.2 | 70 | 29 | 29 | 8 | 19 | 35 | 0 | 0 | 2 | 1.57 | 11.12 | 1.27 | 3.02 | 5.56 | 4.61 | 1.84 | 2013- UDFA -ANA | premium | premium | premium | MLB | 2018-2023 | 2013-2025 | 2021 |
| 62 | Jose Quintana | 32 | L | 0 | 3 | 6.75 | 24 | 10 | 0 | 0 | 14 | 5 | 0 | 53.1 | 66 | 45 | 40 | 9 | 29 | 73 | 5 | 0 | 1 | 1.78 | 11.14 | 1.52 | 4.89 | 12.32 | 7.59 | 2.52 | 2006- UDFA -NYN | premium | premium | premium | MLB | 2012-2025 | 2010-2025 | 2021 |
| 44 | AJ Ramos | 34 | R | 0 | 0 | 0.00 | 4 | 0 | 0 | 0 | 4 | 3 | 0 | 4.2 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 0.43 | 0.00 | 0.00 | 3.86 | 5.79 | 0.00 | 1.50 | 2009- 21- 638-MIA | premium | premium | premium | MLB | 2012-2021 | 2006-2021 | 2021 |
| 68 | Jose Marte | 25 | R | 0 | 1 | 9.00 | 4 | 0 | 0 | 0 | 4 | 2 | 0 | 4.0 | 4 | 5 | 4 | 1 | 3 | 5 | 0 | 0 | 0 | 1.75 | 9.00 | 2.25 | 6.75 | 11.25 | 11.25 | 1.67 | 2015- UDFA -SFN | premium | premium | premium | MLB | 2021-2024 | 2016-2024 | 2021 |
| 56 | Tony Watson | 36 | L | 3 | 3 | 4.64 | 36 | 0 | 0 | 0 | 36 | 4 | 0 | 33.0 | 25 | 18 | 17 | 3 | 14 | 25 | 0 | 0 | 0 | 1.18 | 6.82 | 0.82 | 3.82 | 6.82 | 4.91 | 1.79 | 2007- 9- 278-PIT | premium | premium | premium | MLB | 2011-2021 | 2004-2021 | 2021 |
| 58 | Alex Claudio | 29 | L | 1 | 2 | 5.51 | 41 | 0 | 0 | 0 | 41 | 11 | 1 | 32.2 | 37 | 22 | 20 | 6 | 15 | 30 | 1 | 0 | 0 | 1.59 | 10.19 | 1.65 | 4.13 | 8.27 | 6.06 | 2.00 | 2010- 27- 826-TEX | premium | premium | premium | MLB | 2014-2023 | 2010-2025 | 2021 |
| 57 | Aaron Slegers | 28 | R | 2 | 2 | 6.97 | 29 | 0 | 0 | 0 | 29 | 5 | 0 | 31.0 | 43 | 24 | 24 | 6 | 15 | 25 | 1 | 0 | 1 | 1.87 | 12.48 | 1.74 | 4.35 | 7.26 | 6.97 | 1.67 | 2013- 5- 140-MIN | premium | premium | premium | MLB | 2017-2021 | 2011-2022 | 2021 |
| 56 | Noe Ramirez | 31 | R | 0 | 0 | 5.40 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 3.1 | 5 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 1.80 | 13.50 | 2.70 | 2.70 | 0.00 | 5.40 | 0.00 | 2011- 4- 142-BOS | premium | premium | premium | MLB | 2015-2022 | 2009-2022 | 2021 |
| 73 | Chris Rodriguez | 22 | R | 2 | 1 | 3.64 | 15 | 2 | 0 | 0 | 13 | 1 | 0 | 29.2 | 28 | 14 | 12 | 0 | 15 | 29 | 1 | 0 | 4 | 1.45 | 8.49 | 0.00 | 4.55 | 8.80 | 4.25 | 1.93 | 2016- 4- 126-ANA | premium | premium | premium | MLB | 2021-2021 | 2016-2025 | 2021 |
| 60 | Andrew Wantz | 25 | R | 1 | 0 | 4.94 | 21 | 0 | 0 | 0 | 21 | 3 | 0 | 27.1 | 23 | 17 | 15 | 5 | 11 | 38 | 1 | 0 | 3 | 1.24 | 7.57 | 1.65 | 3.62 | 12.51 | 5.60 | 3.45 | 2018- 7- 211-ANA | premium | premium | premium | MLB | 2021-2024 | 2015-2025 | 2021 |
| 65 | Jose Quijada | 25 | L | 0 | 2 | 4.56 | 26 | 0 | 0 | 0 | 26 | 2 | 0 | 25.2 | 20 | 14 | 13 | 2 | 15 | 38 | 1 | 1 | 1 | 1.36 | 7.01 | 0.70 | 5.26 | 13.32 | 4.91 | 2.53 | 2013- UDFA -MIA | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 58 | Packy Naughton | 25 | L | 0 | 4 | 6.35 | 7 | 5 | 0 | 0 | 2 | 0 | 0 | 22.2 | 27 | 18 | 16 | 3 | 14 | 12 | 0 | 0 | 1 | 1.81 | 10.72 | 1.19 | 5.56 | 4.76 | 7.15 | 0.86 | 2017- 9- 257-CIN | premium | premium | premium | MLB | 2021-2023 | 2015-2024 | 2021 |
| 48 | Reid Detmers | 21 | L | 1 | 3 | 7.40 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 20.2 | 26 | 17 | 17 | 5 | 11 | 19 | 1 | 0 | 2 | 1.79 | 11.32 | 2.18 | 4.79 | 8.27 | 7.40 | 1.73 | 2020- 1- 10-ANA | premium | premium | premium | MLB | 2021-2025 | 2018-2025 | 2021 |
| 61 | Austin Warren | 25 | R | 3 | 0 | 1.77 | 16 | 0 | 0 | 0 | 16 | 1 | 1 | 20.1 | 16 | 5 | 4 | 0 | 5 | 20 | 0 | 0 | 1 | 1.03 | 7.08 | 0.00 | 2.21 | 8.85 | 2.21 | 4.00 | 2018- 6- 181-ANA | premium | premium | premium | MLB | 2021-2025 | 2017-2025 | 2021 |
| 59 | Elvis Peguero | 24 | R | 0 | 1 | 27.00 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 2.1 | 7 | 7 | 7 | 0 | 3 | 0 | 0 | 0 | 1 | 4.29 | 27.00 | 0.00 | 11.57 | 0.00 | 27.00 | 0.00 | 2015- UDFA -NYA | premium | premium | premium | MLB | 2021-2025 | 2016-2025 | 2021 |
| 67 | Sam Selman | 30 | L | 0 | 1 | 6.35 | 18 | 0 | 0 | 0 | 18 | 7 | 0 | 17.0 | 16 | 13 | 12 | 1 | 8 | 11 | 0 | 0 | 4 | 1.41 | 8.47 | 0.53 | 4.24 | 5.82 | 6.88 | 1.38 | 2012- 2- 66-KCA | premium | premium | premium | MLB | 2019-2022 | 2010-2023 | 2021 |
| 66 | Janson Junk | 25 | R | 0 | 1 | 3.86 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 16.1 | 20 | 11 | 7 | 5 | 2 | 10 | 0 | 0 | 0 | 1.35 | 11.02 | 2.76 | 1.10 | 5.51 | 6.06 | 5.00 | 2017- 22- 662-NYA | premium | premium | premium | MLB | 2021-2025 | 2015-2025 | 2021 |
| 45 | Jimmy Herget | 27 | R | 2 | 2 | 4.30 | 14 | 0 | 0 | 0 | 14 | 2 | 0 | 14.2 | 15 | 7 | 7 | 0 | 4 | 18 | 0 | 1 | 2 | 1.30 | 9.20 | 0.00 | 2.45 | 11.05 | 4.30 | 4.50 | 2015- 6- 175-CIN | premium | premium | premium | MLB | 2019-2025 | 2013-2025 | 2021 |
| 17 | Shohei Ohtani | 26 | R | 9 | 2 | 3.18 | 23 | 23 | 0 | 0 | 0 | 0 | 0 | 130.1 | 98 | 48 | 46 | 15 | 44 | 156 | 10 | 2 | 10 | 1.09 | 6.77 | 1.04 | 3.04 | 10.77 | 3.31 | 3.55 | 2017- UDFA -ANA | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 74 | Jhonathan Diaz | 24 | L | 1 | 0 | 4.15 | 3 | 2 | 0 | 0 | 1 | 1 | 0 | 13.0 | 11 | 6 | 6 | 1 | 7 | 9 | 0 | 0 | 1 | 1.38 | 7.62 | 0.69 | 4.85 | 6.23 | 4.15 | 1.29 | 2013- UDFA -BOS | premium | premium | premium | MLB | 2021-2025 | 2014-2025 | 2021 |
| 63 | Kyle Tyler | 24 | R | 0 | 0 | 2.92 | 5 | 0 | 0 | 0 | 5 | 3 | 0 | 12.1 | 8 | 4 | 4 | 1 | 6 | 6 | 0 | 0 | 2 | 1.14 | 5.84 | 0.73 | 4.38 | 4.38 | 2.92 | 1.00 | 2018- 20- 601-ANA | premium | premium | premium | MLB | 2021-2024 | 2016-2025 | 2021 |
| 71 | Ben Rowen | 32 | R | 0 | 0 | 5.56 | 8 | 0 | 0 | 0 | 8 | 5 | 0 | 11.1 | 12 | 8 | 7 | 3 | 2 | 8 | 0 | 0 | 2 | 1.24 | 9.53 | 2.38 | 1.59 | 6.35 | 6.35 | 4.00 | 2010- 22- 676-TEX | premium | premium | premium | MLB | 2014-2021 | 2009-2021 | 2021 |
| 64 | Felix Pena | 31 | R | 0 | 0 | 37.80 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 1.2 | 7 | 7 | 7 | 0 | 4 | 2 | 1 | 0 | 0 | 6.60 | 37.80 | 0.00 | 21.60 | 10.80 | 37.80 | 0.50 | 2009- UDFA -CHN | premium | premium | premium | MLB | 2016-2021 | 2010-2022 | 2021 |
| 56 | Cooper Criswell | 24 | R | 0 | 1 | 20.25 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1.1 | 6 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 4.50 | 40.50 | 0.00 | 0.00 | 0.00 | 20.25 | 0.00 | 2018- 13- 391-ANA | premium | premium | premium | MLB | 2021-2025 | 2017-2025 | 2021 |
| 12 | Anthony Bemboom | 31 | R | 0 | 0 | 18.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 3 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 3.00 | 27.00 | 9.00 | 0.00 | 0.00 | 18.00 | 0.00 | 2012- 22- 687-ANA | premium | premium | premium | MLB | 2019-2023 | 2010-2024 | 2021 |
| 12 | Adam Eaton | 32 | L | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 | 18.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2010- 19- 571-ARI | premium | premium | premium | MLB | 2012-2021 | 2008-2021 | 2021 |
| Totals: | 77 | 85 | 4.69 | 724 | 162 | 1 | 0 | 161 | 562 | 39 | 1421.2 | 1373 | 804 | 741 | 188 | 592 | 1453 | 56 | 11 | 76 | 1.38 | 8.69 | 1.19 | 3.75 | 9.20 | 5.09 | 2.45 | premium | premium | premium |