| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 55 | Stephen Piscotty | 25 | RF | R | 108 | 153 | 582 | 86 | 159 | 35 | 3 | 22 | 85 | 7 | 5 | 51 | 133 | 12 | 2 | 1 | 0 | 14 | 266 | 648 | 60 | 99 | .273 | .344 | .457 | .801 | .275 | .184 | .320 | 7.87 | 20.52 | 2.61 | 26.45 | 2012- 1- 36-SLN | premium | premium | premium | MLB | 2015-2022 | 2010-2024 | 2016 |
| 4 | Yadier Molina | 33 | C | R | 107 | 147 | 534 | 56 | 164 | 38 | 1 | 8 | 58 | 3 | 2 | 39 | 63 | 6 | 2 | 0 | 1 | 22 | 228 | 581 | 47 | 117 | .307 | .361 | .427 | .788 | .195 | .120 | .337 | 6.71 | 10.84 | 1.62 | 66.75 | 2000- 4- 113-SLN | premium | premium | premium | MLB | 2004-2022 | 2001-2022 | 2016 |
| 13 | Matt Carpenter | 30 | 3B-1B | L | 117 | 129 | 473 | 81 | 128 | 36 | 6 | 21 | 68 | 0 | 4 | 81 | 108 | 5 | 4 | 3 | 6 | 4 | 239 | 566 | 63 | 65 | .271 | .381 | .505 | .886 | .397 | .234 | .308 | 14.31 | 19.08 | 1.33 | 22.52 | 2009- 13- 399-SLN | premium | premium | premium | MLB | 2011-2024 | 2005-2024 | 2016 |
| 15 | Randal Grichuk | 24 | CF | R | 102 | 132 | 446 | 66 | 107 | 29 | 3 | 24 | 68 | 5 | 4 | 28 | 141 | 3 | 1 | 0 | 0 | 9 | 214 | 478 | 56 | 51 | .240 | .289 | .480 | .769 | .305 | .240 | .295 | 5.86 | 29.50 | 5.04 | 18.58 | 2009- 1- 24-ANA | premium | premium | premium | MLB | 2014-2025 | 2009-2025 | 2016 |
| 37 | Brandon Moss | 32 | 1B-LF | L | 105 | 128 | 413 | 66 | 93 | 19 | 2 | 28 | 67 | 1 | 0 | 39 | 141 | 7 | 5 | 0 | 3 | 8 | 200 | 464 | 49 | 44 | .225 | .303 | .484 | .787 | .356 | .259 | .266 | 8.41 | 30.39 | 3.62 | 14.75 | 2002- 8- 238-BOS | premium | premium | premium | MLB | 2007-2017 | 2002-2017 | 2016 |
| 36 | Aledmys Diaz | 25 | SS | R | 116 | 111 | 404 | 71 | 121 | 28 | 3 | 17 | 65 | 4 | 4 | 41 | 60 | 7 | 6 | 2 | 6 | 10 | 206 | 460 | 48 | 73 | .300 | .372 | .510 | .882 | .312 | .210 | .316 | 8.91 | 13.04 | 1.46 | 23.76 | 2014- UDFA -SLN | premium | premium | premium | MLB | 2016-2024 | 2014-2025 | 2016 |
| 3 | Jedd Gyorko | 27 | 2B-3B | R | 107 | 128 | 400 | 58 | 97 | 9 | 1 | 30 | 59 | 0 | 0 | 37 | 96 | 0 | 1 | 0 | 1 | 11 | 198 | 438 | 40 | 57 | .243 | .307 | .495 | .802 | .345 | .252 | .245 | 8.45 | 21.92 | 2.59 | 13.33 | 2010- 2- 59-SDN | premium | premium | premium | MLB | 2013-2020 | 2008-2020 | 2016 |
| 7 | Matt Holliday | 36 | LF | R | 106 | 110 | 382 | 48 | 94 | 20 | 1 | 20 | 62 | 0 | 0 | 35 | 71 | 8 | 1 | 0 | 1 | 9 | 176 | 426 | 41 | 53 | .246 | .322 | .461 | .783 | .306 | .215 | .254 | 8.22 | 16.67 | 2.03 | 19.10 | 1998- 7- 210-COL | premium | premium | premium | MLB | 2004-2018 | 1998-2018 | 2016 |
| 16 | Kolten Wong | 25 | 2B | L | 96 | 121 | 313 | 39 | 75 | 7 | 7 | 5 | 23 | 7 | 0 | 34 | 52 | 9 | 5 | 0 | 2 | 3 | 111 | 361 | 19 | 56 | .240 | .331 | .355 | .686 | .246 | .115 | .273 | 9.42 | 14.40 | 1.53 | 62.60 | 2011- 1- 22-SLN | premium | premium | premium | MLB | 2013-2023 | 2009-2024 | 2016 |
| 32 | Matt Adams | 27 | 1B | L | 105 | 118 | 297 | 37 | 74 | 18 | 0 | 16 | 54 | 0 | 1 | 25 | 81 | 2 | 3 | 0 | 1 | 5 | 140 | 327 | 34 | 40 | .249 | .312 | .471 | .783 | .303 | .222 | .290 | 7.65 | 24.77 | 3.24 | 18.56 | 2009- 23- 699-SLN | premium | premium | premium | MLB | 2012-2021 | 2007-2024 | 2016 |
| 27 | Jhonny Peralta | 34 | 3B | R | 97 | 82 | 289 | 37 | 75 | 17 | 1 | 8 | 29 | 0 | 0 | 20 | 56 | 1 | 3 | 0 | 0 | 5 | 118 | 313 | 26 | 49 | .260 | .310 | .408 | .718 | .218 | .148 | .298 | 6.39 | 17.89 | 2.80 | 36.13 | 1999- UDFA -CLE | premium | premium | premium | MLB | 2003-2017 | 2000-2017 | 2016 |
| 35 | Greg Garcia | 26 | 3B-SS | L | 106 | 99 | 214 | 33 | 59 | 11 | 0 | 3 | 17 | 1 | 1 | 38 | 50 | 4 | 1 | 0 | 4 | 3 | 79 | 257 | 14 | 45 | .276 | .395 | .369 | .764 | .271 | .093 | .348 | 14.79 | 19.46 | 1.32 | 71.33 | 2010- 7- 229-SLN | premium | premium | premium | MLB | 2014-2020 | 2008-2020 | 2016 |
| 41 | Jeremy Hazelbaker | 28 | LF | L | 101 | 114 | 200 | 35 | 47 | 7 | 3 | 12 | 28 | 5 | 2 | 18 | 64 | 0 | 2 | 4 | 2 | 1 | 96 | 224 | 22 | 25 | .235 | .293 | .480 | .773 | .350 | .245 | .273 | 8.04 | 28.57 | 3.56 | 16.67 | 2009- 4- 138-BOS | premium | premium | premium | MLB | 2016-2017 | 2007-2019 | 2016 |
| 28 | Tommy Pham | 28 | CF-LF | R | 102* | 78 | 159 | 26 | 36 | 7 | 0 | 9 | 17 | 2 | 2 | 20 | 71 | 3 | 0 | 1 | 1 | 3 | 70 | 183 | 16 | 20 | .226 | .322 | .440 | .762 | .340 | .214 | .338 | 10.93 | 38.80 | 3.55 | 17.67 | 2006- 16- 496-SLN | premium | premium | premium | MLB | 2014-2025 | 2006-2025 | 2016 |
| 50 | Adam Wainwright | 34 | P | R | 32 | 62 | 6 | 14 | 8 | 1 | 2 | 18 | 0 | 0 | 2 | 17 | 0 | 0 | 5 | 0 | 1 | 30 | 69 | 11 | 3 | .226 | .232 | .484 | .716 | .290 | .258 | .250 | 2.90 | 24.64 | 8.50 | 31.00 | 2000- 1- 29-ATL | premium | premium | premium | MLB | 2005-2023 | 2000-2023 | 2016 | |
| 18 | Carlos Martinez | 24 | P | R | 31 | 59 | 5 | 14 | 1 | 0 | 0 | 6 | 0 | 0 | 0 | 13 | 1 | 1 | 4 | 0 | 1 | 15 | 65 | 1 | 13 | .237 | .234 | .254 | .488 | .017 | .017 | .280 | 0.00 | 20.00 | 0.00 | 0.00 | 2009- UDFA -SLN | premium | premium | premium | MLB | 2013-2021 | 2010-2024 | 2016 | |
| 8 | Mike Leake | 28 | P | R | 32 | 49 | 3 | 7 | 1 | 0 | 0 | 4 | 0 | 0 | 3 | 19 | 0 | 0 | 3 | 0 | 3 | 8 | 55 | 1 | 6 | .143 | .182 | .163 | .345 | .082 | .020 | .212 | 5.45 | 34.55 | 6.33 | 0.00 | 2009- 1- 8-CIN | premium | premium | premium | MLB | 2010-2019 | 2007-2019 | 2016 | |
| 54 | Jaime Garcia | 29 | P | L | 29 | 41 | 3 | 7 | 0 | 0 | 0 | 4 | 0 | 0 | 2 | 17 | 0 | 1 | 7 | 0 | 0 | 7 | 51 | 0 | 7 | .171 | .180 | .171 | .351 | .049 | .000 | .226 | 3.92 | 33.33 | 8.50 | 0.00 | 2005- 22- 680-SLN | premium | premium | premium | MLB | 2008-2018 | 2006-2018 | 2016 | |
| 52 | Michael Wacha | 24 | P | R | 26 | 39 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 22 | 0 | 0 | 3 | 0 | 1 | 1 | 45 | 0 | 1 | .026 | .089 | .026 | .115 | .077 | .000 | .050 | 6.67 | 48.89 | 7.33 | 0.00 | 2012- 1- 19-SLN | premium | premium | premium | MLB | 2013-2025 | 2010-2025 | 2016 | |
| 59 | Eric Fryer | 30 | C | R | 88* | 24 | 38 | 7 | 14 | 2 | 0 | 0 | 5 | 0 | 1 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 16 | 41 | 2 | 12 | .368 | .415 | .421 | .836 | .105 | .053 | .452 | 7.32 | 17.07 | 2.33 | 0.00 | 2007- 10- 311-MIL | premium | premium | premium | MLB | 2011-2017 | 2005-2017 | 2016 |
| 68 | Alberto Rosario | 29 | C | R | 20 | 38 | 3 | 7 | 2 | 0 | 0 | 2 | 0 | 0 | 2 | 5 | 0 | 0 | 1 | 0 | 2 | 9 | 41 | 2 | 5 | .184 | .220 | .237 | .457 | .105 | .053 | .206 | 4.88 | 12.20 | 2.50 | 0.00 | 2005- UDFA -ANA | premium | premium | premium | MLB | 2016-2017 | 2007-2019 | 2016 | |
| 19 | Ruben Tejada | 26 | 3B-SS | R | 23 | 34 | 6 | 6 | 2 | 0 | 0 | 3 | 0 | 0 | 2 | 8 | 1 | 3 | 0 | 0 | 1 | 8 | 40 | 2 | 4 | .176 | .243 | .235 | .478 | .118 | .059 | .231 | 5.00 | 20.00 | 4.00 | 0.00 | 2006- UDFA -NYN | premium | premium | premium | MLB | 2010-2019 | 2007-2025 | 2016 | |
| 58 | Jose A. Martinez | 27 | LF | R | 12 | 16 | 4 | 7 | 1 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 8 | 18 | 1 | 6 | .438 | .500 | .500 | 1.000 | .188 | .062 | .467 | 11.11 | 5.56 | 0.50 | 0.00 | 2006- UDFA -CHA | premium | premium | premium | MLB | 2016-2020 | 2007-2024 | 2016 | |
| 61 | Alex Reyes | 21 | P | R | 11 | 14 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 5 | 0 | 0 | 1 | 0 | 1 | 1 | 15 | 0 | 1 | .071 | .067 | .071 | .138 | .000 | .000 | .100 | 0.00 | 33.33 | 0.00 | 0.00 | 2012- UDFA -SLN | premium | premium | premium | MLB | 2016-2021 | 2013-2021 | 2016 | |
| 71 | Carson Kelly | 21 | C | R | 10 | 13 | 1 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3 | 14 | 1 | 1 | .154 | .214 | .231 | .445 | .077 | .077 | .182 | 0.00 | 14.29 | 0.00 | 0.00 | 2012- 2- 86-SLN | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2016 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 62 | Luke Weaver | 22 | P | R | 9 | 13 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 5 | 13 | 0 | 5 | .385 | .385 | .385 | .770 | .000 | .000 | .556 | 0.00 | 30.77 | 0.00 | 0.00 | 2014- 1- 27-SLN | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2016 | |
| 33 | Brayan Pena | 34 | C | B | 9 | 13 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 3 | 14 | 1 | 1 | .154 | .214 | .231 | .445 | .154 | .077 | .182 | 7.14 | 14.29 | 2.00 | 0.00 | 2000- UDFA -ATL | premium | premium | premium | MLB | 2005-2016 | 2001-2017 | 2016 | |
| 70 | Tyler Lyons | 28 | P | L | 28 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2010- 9- 289-SLN | premium | premium | premium | MLB | 2013-2020 | 2007-2020 | 2016 | |
| 26 | Seunghwan Oh | 33 | P | R | 72 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2016- UDFA -SLN | premium | premium | premium | MLB | 2016-2019 | 2014-2019 | 2016 | |
| 38 | Jerome Williams | 34 | P | R | 11 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 1999- 1- 39-SFN | premium | premium | premium | MLB | 2003-2016 | 1999-2018 | 2016 | |
| 60 | Dean Kiekhefer | 27 | P | L | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2010- 36-1099-SLN | premium | premium | premium | MLB | 2016-2018 | 2008-2019 | 2016 | |
| 67 | Matt Bowman | 25 | P | R | 57 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2012- 13- 410-NYN | premium | premium | premium | MLB | 2016-2025 | 2010-2025 | 2016 | |
| 43 | Seth Maness | 27 | P | R | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2011- 11- 350-SLN | premium | premium | premium | MLB | 2013-2017 | 2008-2019 | 2016 | |
| 44 | Trevor Rosenthal | 26 | P | R | 41 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2009- 21- 639-SLN | premium | premium | premium | MLB | 2012-2020 | 2009-2023 | 2016 | |
| 19 | Michael McKenry | 31 | C | R | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2006- 7- 198-COL | premium | premium | premium | MLB | 2010-2016 | 2004-2017 | 2016 | |
| Totals: | 2365 | 5548 | 779 | 1416 | 300 | 32 | 225 | 745 | 35 | 26 | 526 | 1318 | 70 | 41 | 37 | 28 | 117 | 2455 | 6222 | 557 | 859 | .255 | .326 | .443 | .768 | .284 | .187 | .295 | 8.45 | 21.18 | 2.51 | 24.66 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 64 | Sam Tuivailala | 23 | R | 0 | 0 | 6.00 | 12 | 0 | 0 | 0 | 12 | 4 | 0 | 9.0 | 12 | 6 | 6 | 0 | 6 | 7 | 1 | 0 | 2 | 2.00 | 12.00 | 0.00 | 6.00 | 7.00 | 6.00 | 1.17 | 2010- 3- 106-SLN | premium | premium | premium | MLB | 2014-2019 | 2010-2023 | 2016 |
| 26 | Seunghwan Oh | 33 | R | 6 | 3 | 1.92 | 76 | 0 | 0 | 0 | 76 | 35 | 19 | 79.2 | 55 | 20 | 17 | 5 | 18 | 103 | 3 | 0 | 2 | 0.92 | 6.21 | 0.56 | 2.03 | 11.64 | 2.26 | 5.72 | 2016- UDFA -SLN | premium | premium | premium | MLB | 2016-2019 | 2014-2019 | 2016 |
| 67 | Matt Bowman | 25 | R | 2 | 5 | 3.46 | 59 | 0 | 0 | 0 | 59 | 12 | 0 | 67.2 | 59 | 31 | 26 | 4 | 20 | 52 | 0 | 0 | 1 | 1.17 | 7.85 | 0.53 | 2.66 | 6.92 | 4.12 | 2.60 | 2012- 13- 410-NYN | premium | premium | premium | MLB | 2016-2025 | 2010-2025 | 2016 |
| 46 | Kevin Siegrist | 26 | L | 6 | 3 | 2.77 | 67 | 0 | 0 | 0 | 67 | 11 | 3 | 61.2 | 42 | 20 | 19 | 10 | 26 | 66 | 5 | 0 | 1 | 1.10 | 6.13 | 1.46 | 3.79 | 9.63 | 2.92 | 2.54 | 2008- 41-1235-SLN | premium | premium | premium | MLB | 2013-2017 | 2008-2022 | 2016 |
| 30 | Jonathan Broxton | 32 | R | 4 | 2 | 4.30 | 66 | 0 | 0 | 0 | 66 | 14 | 0 | 60.2 | 52 | 32 | 29 | 7 | 24 | 57 | 1 | 0 | 3 | 1.25 | 7.71 | 1.04 | 3.56 | 8.46 | 4.75 | 2.38 | 2002- 2- 60-LAN | premium | premium | premium | MLB | 2005-2017 | 2002-2017 | 2016 |
| 59 | Mike Mayers | 24 | R | 1 | 1 | 27.00 | 4 | 1 | 0 | 0 | 3 | 0 | 0 | 5.1 | 16 | 16 | 16 | 3 | 3 | 2 | 0 | 0 | 1 | 3.56 | 27.00 | 5.06 | 5.06 | 3.38 | 27.00 | 0.67 | 2013- 3- 93-SLN | premium | premium | premium | MLB | 2016-2023 | 2011-2024 | 2016 |
| 70 | Tyler Lyons | 28 | L | 2 | 0 | 3.38 | 30 | 0 | 0 | 0 | 30 | 10 | 0 | 48.0 | 35 | 18 | 18 | 9 | 14 | 46 | 2 | 0 | 0 | 1.02 | 6.56 | 1.69 | 2.63 | 8.63 | 3.38 | 3.29 | 2010- 9- 289-SLN | premium | premium | premium | MLB | 2013-2020 | 2007-2020 | 2016 |
| 61 | Alex Reyes | 21 | R | 4 | 1 | 1.57 | 12 | 5 | 0 | 0 | 7 | 3 | 1 | 46.0 | 33 | 8 | 8 | 1 | 23 | 52 | 3 | 1 | 0 | 1.22 | 6.46 | 0.20 | 4.50 | 10.17 | 1.57 | 2.26 | 2012- UDFA -SLN | premium | premium | premium | MLB | 2016-2021 | 2013-2021 | 2016 |
| 44 | Trevor Rosenthal | 26 | R | 2 | 4 | 4.46 | 45 | 0 | 0 | 0 | 45 | 27 | 14 | 40.1 | 48 | 22 | 20 | 3 | 29 | 56 | 0 | 0 | 3 | 1.91 | 10.71 | 0.67 | 6.47 | 12.50 | 4.91 | 1.93 | 2009- 21- 639-SLN | premium | premium | premium | MLB | 2012-2020 | 2009-2023 | 2016 |
| 62 | Luke Weaver | 22 | R | 1 | 4 | 5.70 | 9 | 8 | 0 | 0 | 1 | 0 | 0 | 36.1 | 46 | 29 | 23 | 7 | 12 | 45 | 1 | 0 | 2 | 1.60 | 11.39 | 1.73 | 2.97 | 11.15 | 7.18 | 3.75 | 2014- 1- 27-SLN | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2016 |
| 43 | Seth Maness | 27 | R | 2 | 2 | 3.41 | 29 | 0 | 0 | 0 | 29 | 13 | 0 | 31.2 | 34 | 14 | 12 | 2 | 8 | 16 | 2 | 0 | 0 | 1.33 | 9.66 | 0.57 | 2.27 | 4.55 | 3.98 | 2.00 | 2011- 11- 350-SLN | premium | premium | premium | MLB | 2013-2017 | 2008-2019 | 2016 |
| 29 | Zach Duke | 33 | L | 0 | 1 | 1.93 | 28 | 0 | 0 | 0 | 28 | 4 | 1 | 23.1 | 17 | 5 | 5 | 0 | 13 | 26 | 2 | 0 | 2 | 1.29 | 6.56 | 0.00 | 5.01 | 10.03 | 1.93 | 2.00 | 2001- 20- 594-PIT | premium | premium | premium | MLB | 2005-2019 | 2002-2019 | 2016 |
| 60 | Dean Kiekhefer | 27 | L | 0 | 0 | 5.32 | 26 | 0 | 0 | 0 | 26 | 10 | 0 | 22.0 | 24 | 13 | 13 | 2 | 7 | 14 | 0 | 0 | 2 | 1.41 | 9.82 | 0.82 | 2.86 | 5.73 | 5.32 | 2.00 | 2010- 36-1099-SLN | premium | premium | premium | MLB | 2016-2018 | 2008-2019 | 2016 |
| 50 | Adam Wainwright | 34 | R | 13 | 9 | 4.62 | 33 | 33 | 1 | 1 | 0 | 0 | 0 | 198.2 | 220 | 108 | 102 | 22 | 59 | 161 | 1 | 0 | 5 | 1.40 | 9.97 | 1.00 | 2.67 | 7.29 | 4.89 | 2.73 | 2000- 1- 29-ATL | premium | premium | premium | MLB | 2005-2023 | 2000-2023 | 2016 |
| 18 | Carlos Martinez | 24 | R | 16 | 9 | 3.04 | 31 | 31 | 0 | 0 | 0 | 0 | 0 | 195.1 | 169 | 68 | 66 | 15 | 70 | 174 | 8 | 0 | 11 | 1.22 | 7.79 | 0.69 | 3.23 | 8.02 | 3.13 | 2.49 | 2009- UDFA -SLN | premium | premium | premium | MLB | 2013-2021 | 2010-2024 | 2016 |
| 63 | Miguel Socolovich | 29 | R | 1 | 0 | 2.00 | 15 | 0 | 0 | 0 | 15 | 6 | 0 | 18.0 | 5 | 4 | 4 | 2 | 5 | 16 | 0 | 0 | 0 | 0.56 | 2.50 | 1.00 | 2.50 | 8.00 | 2.00 | 3.20 | 2004- UDFA -BOS | premium | premium | premium | MLB | 2012-2018 | 2006-2019 | 2016 |
| 8 | Mike Leake | 28 | R | 9 | 12 | 4.69 | 30 | 30 | 0 | 0 | 0 | 0 | 0 | 176.2 | 203 | 101 | 92 | 20 | 30 | 125 | 7 | 0 | 7 | 1.32 | 10.34 | 1.02 | 1.53 | 6.37 | 5.15 | 4.17 | 2009- 1- 8-CIN | premium | premium | premium | MLB | 2010-2019 | 2007-2019 | 2016 |
| 54 | Jaime Garcia | 29 | L | 10 | 13 | 4.67 | 32 | 30 | 1 | 1 | 2 | 0 | 0 | 171.2 | 179 | 94 | 89 | 26 | 57 | 150 | 8 | 0 | 7 | 1.37 | 9.38 | 1.36 | 2.99 | 7.86 | 4.93 | 2.63 | 2005- 22- 680-SLN | premium | premium | premium | MLB | 2008-2018 | 2006-2018 | 2016 |
| 38 | Jerome Williams | 34 | R | 0 | 0 | 5.71 | 11 | 0 | 0 | 0 | 11 | 9 | 0 | 17.1 | 22 | 15 | 11 | 4 | 6 | 8 | 0 | 0 | 2 | 1.62 | 11.42 | 2.08 | 3.12 | 4.15 | 7.79 | 1.33 | 1999- 1- 39-SFN | premium | premium | premium | MLB | 2003-2016 | 1999-2018 | 2016 |
| 52 | Michael Wacha | 24 | R | 7 | 7 | 5.09 | 27 | 24 | 0 | 0 | 3 | 1 | 0 | 138.0 | 159 | 86 | 78 | 15 | 45 | 114 | 6 | 0 | 1 | 1.48 | 10.37 | 0.98 | 2.93 | 7.43 | 5.61 | 2.53 | 2012- 1- 19-SLN | premium | premium | premium | MLB | 2013-2025 | 2010-2025 | 2016 |
| 19 | Ruben Tejada | 26 | R | 0 | 0 | 18.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 2 | 2 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 2.00 | 18.00 | 18.00 | 0.00 | 0.00 | 18.00 | 0.00 | 2006- UDFA -NYN | premium | premium | premium | MLB | 2010-2019 | 2007-2025 | 2016 |
| Totals: | 86 | 76 | 4.08 | 643 | 162 | 2 | 2 | 160 | 481 | 38 | 1448.1 | 1432 | 712 | 656 | 159 | 475 | 1290 | 50 | 1 | 52 | 1.32 | 8.90 | 0.99 | 2.95 | 8.02 | 4.42 | 2.72 | premium | premium | premium |