| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 22 | Andrew McCutchen | 29 | CF | R | 103 | 153 | 598 | 81 | 153 | 26 | 3 | 24 | 79 | 6 | 7 | 69 | 143 | 5 | 3 | 0 | 7 | 15 | 257 | 675 | 53 | 100 | .256 | .338 | .430 | .768 | .288 | .174 | .299 | 10.22 | 21.19 | 2.07 | 24.92 | 2005- 1- 11-PIT | premium | premium | premium | MLB | 2009-2025 | 2005-2025 | 2016 |
| 25 | Gregory Polanco | 24 | RF | L | 105 | 144 | 527 | 79 | 136 | 34 | 4 | 22 | 86 | 17 | 6 | 53 | 119 | 0 | 6 | 1 | 6 | 13 | 244 | 587 | 60 | 76 | .258 | .325 | .463 | .788 | .326 | .205 | .295 | 9.03 | 20.27 | 2.25 | 23.95 | 2009- UDFA -PIT | premium | premium | premium | MLB | 2014-2021 | 2010-2025 | 2016 |
| 10 | Jordy Mercer | 29 | SS | R | 94 | 149 | 519 | 66 | 133 | 22 | 3 | 11 | 59 | 1 | 1 | 51 | 83 | 5 | 2 | 7 | 8 | 11 | 194 | 584 | 36 | 97 | .256 | .325 | .374 | .699 | .216 | .118 | .282 | 8.73 | 14.21 | 1.63 | 47.18 | 2008- 3- 79-PIT | premium | premium | premium | MLB | 2012-2021 | 2006-2021 | 2016 |
| 6 | Starling Marte | 27 | LF | R | 112 | 129 | 489 | 71 | 152 | 34 | 5 | 9 | 46 | 47 | 12 | 23 | 104 | 16 | 0 | 1 | 5 | 8 | 223 | 529 | 48 | 104 | .311 | .361 | .456 | .817 | .264 | .145 | .379 | 4.35 | 19.66 | 4.52 | 54.33 | 2007- UDFA -PIT | premium | premium | premium | MLB | 2012-2025 | 2009-2025 | 2016 |
| 5 | Josh Harrison | 28 | 2B | R | 96 | 131 | 487 | 57 | 138 | 25 | 7 | 4 | 59 | 19 | 4 | 18 | 76 | 5 | 8 | 4 | 0 | 10 | 189 | 522 | 36 | 102 | .283 | .313 | .388 | .701 | .172 | .105 | .326 | 3.45 | 14.56 | 4.22 | 121.75 | 2008- 6- 191-CHN | premium | premium | premium | MLB | 2011-2023 | 2006-2023 | 2016 |
| 23 | David Freese | 33 | 3B-1B | R | 105 | 141 | 437 | 63 | 118 | 23 | 0 | 13 | 55 | 0 | 0 | 45 | 142 | 10 | 0 | 0 | 2 | 15 | 180 | 492 | 36 | 82 | .270 | .352 | .412 | .764 | .245 | .142 | .372 | 9.15 | 28.86 | 3.16 | 33.62 | 2006- 9- 273-SDN | premium | premium | premium | MLB | 2009-2019 | 2005-2019 | 2016 |
| 28 | John Jaso | 32 | 1B | L | 104 | 132 | 380 | 45 | 102 | 25 | 3 | 8 | 42 | 0 | 4 | 45 | 74 | 5 | 1 | 1 | 0 | 8 | 157 | 432 | 36 | 66 | .268 | .353 | .413 | .766 | .253 | .145 | .314 | 10.42 | 17.13 | 1.64 | 47.50 | 2003- 12- 338-TBA | premium | premium | premium | MLB | 2008-2017 | 2003-2017 | 2016 |
| 29 | Francisco Cervelli | 30 | C | R | 101 | 101 | 326 | 42 | 86 | 14 | 1 | 1 | 33 | 6 | 2 | 56 | 72 | 6 | 5 | 0 | 1 | 14 | 105 | 393 | 16 | 70 | .264 | .381 | .322 | .703 | .242 | .058 | .336 | 14.25 | 18.32 | 1.29 | 326.00 | 2003- UDFA -NYA | premium | premium | premium | MLB | 2008-2020 | 2005-2020 | 2016 |
| 27 | Jung Ho Kang | 29 | 3B | R | 117 | 103 | 318 | 45 | 81 | 19 | 0 | 21 | 62 | 3 | 1 | 36 | 79 | 14 | 2 | 0 | 1 | 11 | 163 | 370 | 40 | 41 | .255 | .356 | .513 | .869 | .377 | .258 | .275 | 9.73 | 21.35 | 2.19 | 15.14 | 2015- UDFA -PIT | premium | premium | premium | MLB | 2015-2019 | 2015-2019 | 2016 |
| 3 | Sean Rodriguez | 31 | 1B-2B | R | 115 | 140 | 300 | 49 | 81 | 16 | 1 | 18 | 56 | 2 | 1 | 33 | 102 | 5 | 3 | 1 | 2 | 6 | 153 | 342 | 35 | 46 | .270 | .351 | .510 | .861 | .353 | .240 | .348 | 9.65 | 29.82 | 3.09 | 16.67 | 2003- 3- 90-ANA | premium | premium | premium | MLB | 2008-2020 | 2003-2020 | 2016 |
| 17 | Matt Joyce | 31 | RF-LF | L | 117 | 140 | 231 | 45 | 56 | 10 | 1 | 13 | 42 | 1 | 1 | 59 | 67 | 3 | 0 | 0 | 4 | 9 | 107 | 293 | 24 | 32 | .242 | .403 | .463 | .866 | .476 | .221 | .285 | 20.14 | 22.87 | 1.14 | 17.77 | 2005- 12- 360-DET | premium | premium | premium | MLB | 2008-2021 | 2003-2021 | 2016 |
| 26 | Adam Frazier | 24 | LF-2B | L | 106* | 66 | 146 | 21 | 44 | 8 | 1 | 2 | 11 | 4 | 1 | 12 | 26 | 1 | 1 | 0 | 0 | 0 | 60 | 160 | 11 | 33 | .301 | .358 | .411 | .769 | .212 | .110 | .356 | 7.50 | 16.25 | 2.17 | 73.00 | 2013- 6- 179-PIT | premium | premium | premium | MLB | 2016-2025 | 2011-2025 | 2016 |
| 55 | Josh Bell | 23 | 1B-RF | B | 107* | 45 | 128 | 18 | 35 | 8 | 0 | 3 | 19 | 0 | 1 | 21 | 19 | 0 | 3 | 0 | 0 | 4 | 52 | 152 | 11 | 24 | .273 | .376 | .406 | .782 | .289 | .133 | .302 | 13.82 | 12.50 | 0.90 | 42.67 | 2011- 2- 61-PIT | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2016 |
| 19 | Chris Stewart | 34 | C | R | 85* | 34 | 98 | 10 | 21 | 4 | 0 | 1 | 7 | 0 | 0 | 12 | 15 | 3 | 0 | 0 | 2 | 2 | 28 | 113 | 5 | 16 | .214 | .319 | .286 | .605 | .194 | .072 | .244 | 10.62 | 13.27 | 1.25 | 98.00 | 2001- 12- 373-CHA | premium | premium | premium | MLB | 2006-2018 | 2001-2019 | 2016 |
| 24 | Eric Fryer | 30 | C | R | 88* | 36 | 78 | 12 | 17 | 2 | 1 | 0 | 8 | 0 | 2 | 10 | 18 | 0 | 2 | 2 | 0 | 1 | 21 | 92 | 3 | 14 | .218 | .300 | .269 | .569 | .154 | .051 | .274 | 10.87 | 19.57 | 1.80 | 0.00 | 2007- 10- 311-MIL | premium | premium | premium | MLB | 2011-2017 | 2005-2017 | 2016 |
| 38 | Erik Kratz | 36 | C | R | 18 | 56 | 3 | 6 | 1 | 0 | 1 | 4 | 0 | 0 | 0 | 18 | 0 | 0 | 1 | 0 | 2 | 10 | 57 | 2 | 4 | .107 | .105 | .179 | .284 | .071 | .072 | .132 | 0.00 | 31.58 | 0.00 | 56.00 | 2002- 29- 866-TOR | premium | premium | premium | MLB | 2010-2020 | 2002-2020 | 2016 | |
| 47 | Francisco Liriano | 32 | P | L | 21 | 42 | 2 | 12 | 1 | 0 | 1 | 5 | 0 | 0 | 0 | 16 | 0 | 0 | 0 | 0 | 0 | 16 | 42 | 2 | 10 | .286 | .286 | .381 | .667 | .095 | .095 | .440 | 0.00 | 38.10 | 0.00 | 42.00 | 2000- UDFA -SFN | premium | premium | premium | MLB | 2005-2019 | 2001-2019 | 2016 | |
| 45 | Gerrit Cole | 25 | P | R | 21 | 40 | 3 | 8 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 19 | 1 | 0 | 2 | 0 | 0 | 12 | 43 | 2 | 6 | .200 | .209 | .300 | .509 | .100 | .100 | .318 | 0.00 | 44.19 | 0.00 | 40.00 | 2011- 1- 1-PIT | premium | premium | premium | MLB | 2013-2024 | 2009-2024 | 2016 | |
| 49 | Jeff Locke | 28 | P | L | 30 | 32 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 17 | 0 | 0 | 6 | 0 | 0 | 4 | 39 | 0 | 4 | .125 | .128 | .125 | .253 | .031 | .000 | .190 | 2.56 | 43.59 | 17.00 | 0.00 | 2006- 2- 51-ATL | premium | premium | premium | MLB | 2011-2017 | 2006-2017 | 2016 | |
| 50 | Jameson Taillon | 24 | P | R | 17 | 32 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 17 | 0 | 0 | 4 | 0 | 2 | 3 | 36 | 0 | 3 | .094 | .083 | .094 | .177 | .000 | .000 | .158 | 0.00 | 47.22 | 0.00 | 0.00 | 2010- 1- 2-PIT | premium | premium | premium | MLB | 2016-2025 | 2011-2025 | 2016 | |
| 37 | Alen Hanson | 23 | 2B | B | 27 | 31 | 5 | 7 | 1 | 0 | 0 | 1 | 2 | 1 | 2 | 5 | 0 | 0 | 0 | 1 | 0 | 8 | 33 | 1 | 6 | .226 | .273 | .258 | .531 | .129 | .032 | .269 | 6.06 | 15.15 | 2.50 | 0.00 | 2009- UDFA -PIT | premium | premium | premium | MLB | 2016-2019 | 2010-2025 | 2016 | |
| 18 | Jonathon Niese | 29 | P | L | 21 | 30 | 1 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 2 | 14 | 0 | 0 | 1 | 0 | 1 | 4 | 33 | 1 | 2 | .100 | .152 | .133 | .285 | .100 | .033 | .176 | 6.06 | 42.42 | 7.00 | 0.00 | 2005- 7- 209-NYN | premium | premium | premium | MLB | 2008-2016 | 2005-2019 | 2016 | |
| 24 | Cole Figueroa | 29 | 2B | L | 23 | 26 | 0 | 4 | 0 | 0 | 0 | 3 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 4 | 27 | 0 | 4 | .154 | .185 | .154 | .339 | .077 | .000 | .167 | 3.70 | 7.41 | 2.00 | 0.00 | 2008- 6- 195-SDN | premium | premium | premium | MLB | 2014-2016 | 2007-2016 | 2016 | |
| 15 | Jason Rogers | 28 | 1B-3B | R | 23 | 25 | 2 | 2 | 0 | 1 | 0 | 2 | 0 | 0 | 7 | 9 | 1 | 0 | 0 | 0 | 1 | 4 | 33 | 1 | 1 | .080 | .303 | .160 | .463 | .360 | .080 | .125 | 21.21 | 27.27 | 1.29 | 0.00 | 2010- 32- 969-MIL | premium | premium | premium | MLB | 2014-2016 | 2010-2023 | 2016 | |
| 18 | Pedro Florimon | 29 | 2B-SS | B | 18 | 24 | 4 | 5 | 1 | 1 | 0 | 4 | 0 | 1 | 1 | 12 | 0 | 0 | 0 | 0 | 0 | 8 | 25 | 2 | 3 | .208 | .240 | .333 | .573 | .125 | .125 | .417 | 4.00 | 48.00 | 12.00 | 0.00 | 2004- UDFA -BAL | premium | premium | premium | MLB | 2011-2018 | 2006-2022 | 2016 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 39 | Chad Kuhl | 23 | P | R | 14 | 23 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 9 | 0 | 0 | 2 | 0 | 0 | 2 | 26 | 0 | 2 | .087 | .115 | .087 | .202 | .043 | .000 | .125 | 3.85 | 34.62 | 9.00 | 0.00 | 2013- 9- 269-PIT | premium | premium | premium | MLB | 2016-2024 | 2011-2025 | 2016 | |
| 46 | Ivan Nova | 29 | P | R | 11 | 22 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15 | 0 | 0 | 2 | 0 | 0 | 3 | 24 | 0 | 3 | .136 | .125 | .136 | .261 | .000 | .000 | .333 | 0.00 | 62.50 | 0.00 | 0.00 | 2004- UDFA -NYA | premium | premium | premium | MLB | 2010-2020 | 2006-2020 | 2016 | |
| 12 | Juan Nicasio | 29 | P | R | 49 | 19 | 1 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 7 | 0 | 0 | 1 | 0 | 0 | 3 | 20 | 0 | 3 | .158 | .150 | .158 | .308 | .000 | .000 | .231 | 0.00 | 35.00 | 0.00 | 0.00 | 2006- UDFA -COL | premium | premium | premium | MLB | 2011-2020 | 2007-2020 | 2016 | |
| 14 | Ryan Vogelsong | 38 | P | R | 24 | 19 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 13 | 1 | 0 | 2 | 0 | 0 | 1 | 23 | 0 | 1 | .053 | .130 | .053 | .183 | .053 | .000 | .125 | 4.35 | 56.52 | 13.00 | 0.00 | 1998- 5- 158-SFN | premium | premium | premium | MLB | 2000-2016 | 1998-2016 | 2016 | |
| 58 | Jacob Stallings | 26 | C | R | 5 | 15 | 0 | 6 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 7 | 15 | 1 | 5 | .400 | .400 | .467 | .867 | .133 | .067 | .545 | 0.00 | 26.67 | 0.00 | 0.00 | 2012- 7- 226-PIT | premium | premium | premium | MLB | 2016-2025 | 2009-2025 | 2016 | |
| 43 | Steven Brault | 24 | P | L | 8 | 8 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 9 | 0 | 2 | .250 | .222 | .250 | .472 | .000 | .000 | .222 | 0.00 | 0.00 | 0.00 | 0.00 | 2013- 11- 339-BAL | premium | premium | premium | MLB | 2016-2022 | 2013-2023 | 2016 | |
| 38 | Michael Morse | 34 | DH-1B | R | 6 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 25.00 | 0.00 | 0.00 | 2000- 3- 82-CHA | premium | premium | premium | MLB | 2005-2017 | 2000-2017 | 2016 | |
| 51 | Tyler Glasnow | 22 | P | L | 7 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 7 | 0 | 1 | .143 | .143 | .143 | .286 | .000 | .000 | .333 | 0.00 | 57.14 | 0.00 | 0.00 | 2011- 5- 152-PIT | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2016 | |
| 0 | Elias Diaz | 25 | C | R | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 25.00 | 0.00 | 0.00 | 2008- UDFA -PIT | premium | premium | premium | MLB | 2015-2025 | 2010-2025 | 2016 | |
| 69 | Wilfredo Boscan | 26 | P | R | 5 | 3 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 1 | .333 | .333 | .333 | .666 | .000 | .000 | .500 | 0.00 | 33.33 | 0.00 | 0.00 | 2006- UDFA -TEX | premium | premium | premium | MLB | 2016-2016 | 2008-2025 | 2016 | |
| 52 | Rob Scahill | 29 | P | L | 13 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2009- 8- 241-COL | premium | premium | premium | MLB | 2012-2018 | 2006-2018 | 2016 | |
| 31 | A.J. Schugel | 27 | P | R | 32 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 2010- 25- 774-ANA | premium | premium | premium | MLB | 2015-2017 | 2008-2024 | 2016 | |
| 37 | Arquimedes Caminero | 29 | P | R | 37 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2005- UDFA -MIA | premium | premium | premium | MLB | 2013-2016 | 2008-2021 | 2016 | |
| 38 | Max Moroff | 23 | 2B-3B | B | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2012- 16- 496-PIT | premium | premium | premium | MLB | 2016-2021 | 2012-2021 | 2016 | |
| 53 | Kyle Lobstein | 26 | P | L | 13 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2008- 2- 47-TBA | premium | premium | premium | MLB | 2014-2021 | 2009-2025 | 2016 | |
| 38 | Wade LeBlanc | 31 | P | L | 8 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2006- 2- 61-SDN | premium | premium | premium | MLB | 2008-2021 | 2004-2021 | 2016 | |
| 48 | Jared Hughes | 30 | P | R | 65 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2006- 4- 110-PIT | premium | premium | premium | MLB | 2011-2020 | 2004-2020 | 2016 | |
| 57 | Trevor Williams | 24 | P | R | 7 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .667 | .000 | .667 | 2.000 | .000 | .000 | 66.67 | 33.33 | 0.50 | 0.00 | 2013- 2- 44-MIA | premium | premium | premium | MLB | 2016-2025 | 2011-2025 | 2016 | |
| 34 | Drew Hutchison | 25 | P | L | 6 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2009- 15- 460-TOR | premium | premium | premium | MLB | 2012-2022 | 2010-2024 | 2016 | |
| 44 | Tony Watson | 31 | P | L | 65 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2007- 9- 278-PIT | premium | premium | premium | MLB | 2011-2021 | 2004-2021 | 2016 | |
| Totals: | 2417 | 5542 | 729 | 1426 | 277 | 32 | 153 | 696 | 110 | 45 | 561 | 1334 | 81 | 36 | 41 | 39 | 133 | 2226 | 6261 | 462 | 964 | .257 | .332 | .402 | .734 | .257 | .144 | .311 | 8.96 | 21.31 | 2.38 | 36.22 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 14 | Ryan Vogelsong | 38 | R | 3 | 7 | 4.81 | 24 | 14 | 0 | 0 | 10 | 2 | 0 | 82.1 | 81 | 51 | 44 | 11 | 40 | 61 | 4 | 0 | 4 | 1.47 | 8.85 | 1.20 | 4.37 | 6.67 | 5.57 | 1.53 | 1998- 5- 158-SFN | premium | premium | premium | MLB | 2000-2016 | 1998-2016 | 2016 |
| 26 | Cory Luebke | 31 | L | 0 | 1 | 9.35 | 9 | 0 | 0 | 0 | 9 | 5 | 0 | 8.2 | 15 | 9 | 9 | 2 | 11 | 9 | 0 | 0 | 1 | 3.00 | 15.58 | 2.08 | 11.42 | 9.35 | 9.35 | 0.82 | 2007- 1- 63-SDN | premium | premium | premium | MLB | 2010-2016 | 2005-2017 | 2016 |
| 39 | Chad Kuhl | 23 | R | 5 | 4 | 4.20 | 14 | 14 | 0 | 0 | 0 | 0 | 0 | 70.2 | 73 | 34 | 33 | 7 | 20 | 53 | 2 | 0 | 4 | 1.32 | 9.30 | 0.89 | 2.55 | 6.75 | 4.33 | 2.65 | 2013- 9- 269-PIT | premium | premium | premium | MLB | 2016-2024 | 2011-2025 | 2016 |
| 44 | Tony Watson | 31 | L | 2 | 5 | 3.06 | 70 | 0 | 0 | 0 | 70 | 27 | 15 | 67.2 | 52 | 26 | 23 | 10 | 20 | 58 | 0 | 0 | 3 | 1.06 | 6.92 | 1.33 | 2.66 | 7.71 | 3.46 | 2.90 | 2007- 9- 278-PIT | premium | premium | premium | MLB | 2011-2021 | 2004-2021 | 2016 |
| 46 | Ivan Nova | 29 | R | 5 | 2 | 3.06 | 11 | 11 | 3 | 0 | 0 | 0 | 0 | 64.2 | 68 | 27 | 22 | 4 | 3 | 52 | 3 | 0 | 3 | 1.10 | 9.46 | 0.56 | 0.42 | 7.24 | 3.76 | 17.33 | 2004- UDFA -NYA | premium | premium | premium | MLB | 2010-2020 | 2006-2020 | 2016 |
| 53 | Zach Phillips | 29 | L | 0 | 0 | 2.70 | 8 | 0 | 0 | 0 | 8 | 0 | 0 | 6.2 | 8 | 2 | 2 | 1 | 1 | 6 | 1 | 0 | 0 | 1.35 | 10.80 | 1.35 | 1.35 | 8.10 | 2.70 | 6.00 | 2004- 23- 681-TEX | premium | premium | premium | MLB | 2011-2016 | 2005-2025 | 2016 |
| 48 | Jared Hughes | 30 | R | 1 | 1 | 3.03 | 67 | 0 | 0 | 0 | 67 | 18 | 1 | 59.1 | 62 | 24 | 20 | 6 | 22 | 34 | 5 | 0 | 5 | 1.42 | 9.40 | 0.91 | 3.34 | 5.16 | 3.64 | 1.55 | 2006- 4- 110-PIT | premium | premium | premium | MLB | 2011-2020 | 2004-2020 | 2016 |
| 30 | Neftali Feliz | 28 | R | 4 | 2 | 3.52 | 62 | 0 | 0 | 0 | 62 | 6 | 2 | 53.2 | 40 | 21 | 21 | 10 | 21 | 61 | 3 | 0 | 1 | 1.14 | 6.71 | 1.68 | 3.52 | 10.23 | 3.52 | 2.90 | 2005- UDFA -ATL | premium | premium | premium | MLB | 2009-2021 | 2006-2025 | 2016 |
| 31 | A.J. Schugel | 27 | R | 2 | 2 | 3.63 | 36 | 0 | 0 | 0 | 36 | 11 | 1 | 52.0 | 41 | 22 | 21 | 4 | 13 | 46 | 2 | 0 | 1 | 1.04 | 7.10 | 0.69 | 2.25 | 7.96 | 3.81 | 3.54 | 2010- 25- 774-ANA | premium | premium | premium | MLB | 2015-2017 | 2008-2024 | 2016 |
| 35 | Mark Melancon | 31 | R | 1 | 1 | 1.51 | 45 | 0 | 0 | 0 | 45 | 39 | 30 | 41.2 | 31 | 10 | 7 | 2 | 9 | 38 | 1 | 0 | 1 | 0.96 | 6.70 | 0.43 | 1.94 | 8.21 | 2.16 | 4.22 | 2006- 9- 284-NYA | premium | premium | premium | MLB | 2009-2022 | 2004-2023 | 2016 |
| 37 | Arquimedes Caminero | 29 | R | 1 | 2 | 3.51 | 39 | 0 | 0 | 0 | 39 | 9 | 1 | 41.0 | 46 | 17 | 16 | 4 | 22 | 32 | 1 | 0 | 4 | 1.66 | 10.10 | 0.88 | 4.83 | 7.02 | 3.73 | 1.45 | 2005- UDFA -MIA | premium | premium | premium | MLB | 2013-2016 | 2008-2021 | 2016 |
| 52 | Phil Coke | 33 | L | 0 | 0 | 0.00 | 3 | 0 | 0 | 0 | 3 | 1 | 0 | 4.0 | 3 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 1.50 | 6.75 | 0.00 | 6.75 | 6.75 | 0.00 | 1.00 | 2002- 26- 786-NYA | premium | premium | premium | MLB | 2008-2016 | 2003-2018 | 2016 |
| 43 | Steven Brault | 24 | L | 0 | 3 | 4.86 | 8 | 7 | 0 | 0 | 1 | 0 | 0 | 33.1 | 45 | 26 | 18 | 5 | 17 | 29 | 1 | 0 | 2 | 1.86 | 12.15 | 1.35 | 4.59 | 7.83 | 7.02 | 1.71 | 2013- 11- 339-BAL | premium | premium | premium | MLB | 2016-2022 | 2013-2023 | 2016 |
| 57 | Jorge Rondon | 28 | R | 0 | 0 | 17.18 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 3.2 | 9 | 7 | 7 | 1 | 1 | 4 | 1 | 0 | 0 | 2.73 | 22.09 | 2.45 | 2.45 | 9.82 | 17.18 | 4.00 | 2006- UDFA -SLN | premium | premium | premium | MLB | 2014-2016 | 2008-2025 | 2016 |
| 58 | Kelvin Marte | 28 | L | 0 | 0 | 0.00 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 3.1 | 5 | 5 | 0 | 2 | 2 | 1 | 0 | 0 | 0 | 2.10 | 13.50 | 5.40 | 5.40 | 2.70 | 13.50 | 0.50 | 2007- UDFA -SFN | premium | premium | premium | MLB | 2016-2016 | 2008-2019 | 2016 |
| 73 | Felipe Vazquez | 24 | L | 1 | 3 | 3.29 | 28 | 0 | 0 | 0 | 28 | 3 | 0 | 27.1 | 23 | 13 | 10 | 3 | 18 | 39 | 2 | 0 | 1 | 1.50 | 7.57 | 0.99 | 5.93 | 12.84 | 4.28 | 2.17 | 2008- UDFA -TBA | premium | premium | premium | MLB | 2015-2019 | 2011-2019 | 2016 |
| 53 | Kyle Lobstein | 26 | L | 2 | 0 | 3.96 | 14 | 0 | 0 | 0 | 14 | 3 | 0 | 25.0 | 25 | 11 | 11 | 2 | 12 | 15 | 2 | 0 | 2 | 1.48 | 9.00 | 0.72 | 4.32 | 5.40 | 3.96 | 1.25 | 2008- 2- 47-TBA | premium | premium | premium | MLB | 2014-2021 | 2009-2025 | 2016 |
| 59 | Antonio Bastardo | 30 | L | 3 | 0 | 4.13 | 28 | 0 | 0 | 0 | 28 | 0 | 0 | 24.0 | 19 | 13 | 11 | 3 | 11 | 28 | 5 | 2 | 1 | 1.25 | 7.13 | 1.13 | 4.13 | 10.50 | 4.88 | 2.55 | 2005- UDFA -PHI | premium | premium | premium | MLB | 2009-2017 | 2006-2017 | 2016 |
| 51 | Tyler Glasnow | 22 | R | 0 | 2 | 4.24 | 7 | 4 | 0 | 0 | 3 | 0 | 0 | 23.1 | 22 | 13 | 11 | 2 | 13 | 24 | 2 | 1 | 3 | 1.50 | 8.49 | 0.77 | 5.01 | 9.26 | 5.01 | 1.85 | 2011- 5- 152-PIT | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2016 |
| 52 | Rob Scahill | 29 | R | 0 | 0 | 4.41 | 15 | 0 | 0 | 0 | 15 | 5 | 0 | 16.1 | 18 | 9 | 8 | 1 | 6 | 13 | 1 | 0 | 2 | 1.47 | 9.92 | 0.55 | 3.31 | 7.16 | 4.96 | 2.17 | 2009- 8- 241-COL | premium | premium | premium | MLB | 2012-2018 | 2006-2018 | 2016 |
| 69 | Wilfredo Boscan | 26 | R | 1 | 1 | 6.46 | 6 | 1 | 0 | 0 | 5 | 2 | 0 | 15.1 | 15 | 11 | 11 | 2 | 7 | 8 | 1 | 1 | 0 | 1.43 | 8.80 | 1.17 | 4.11 | 4.70 | 6.46 | 1.14 | 2006- UDFA -TEX | premium | premium | premium | MLB | 2016-2016 | 2008-2025 | 2016 |
| 49 | Jeff Locke | 28 | L | 9 | 8 | 5.44 | 30 | 19 | 1 | 1 | 11 | 4 | 0 | 127.1 | 151 | 81 | 77 | 17 | 44 | 73 | 7 | 0 | 3 | 1.53 | 10.67 | 1.20 | 3.11 | 5.16 | 5.73 | 1.66 | 2006- 2- 51-ATL | premium | premium | premium | MLB | 2011-2017 | 2006-2017 | 2016 |
| 57 | Trevor Williams | 24 | R | 1 | 1 | 7.82 | 7 | 1 | 0 | 0 | 6 | 1 | 0 | 12.2 | 19 | 13 | 11 | 4 | 5 | 11 | 0 | 0 | 0 | 1.89 | 13.50 | 2.84 | 3.55 | 7.82 | 9.24 | 2.20 | 2013- 2- 44-MIA | premium | premium | premium | MLB | 2016-2025 | 2011-2025 | 2016 |
| 38 | Wade LeBlanc | 31 | L | 1 | 0 | 0.75 | 8 | 0 | 0 | 0 | 8 | 4 | 1 | 12.0 | 7 | 3 | 1 | 0 | 2 | 10 | 0 | 0 | 0 | 0.75 | 5.25 | 0.00 | 1.50 | 7.50 | 2.25 | 5.00 | 2006- 2- 61-SDN | premium | premium | premium | MLB | 2008-2021 | 2004-2021 | 2016 |
| 12 | Juan Nicasio | 29 | R | 10 | 7 | 4.50 | 52 | 12 | 0 | 0 | 40 | 9 | 0 | 118.0 | 117 | 64 | 59 | 15 | 45 | 138 | 3 | 0 | 7 | 1.37 | 8.92 | 1.14 | 3.43 | 10.53 | 4.88 | 3.07 | 2006- UDFA -COL | premium | premium | premium | MLB | 2011-2020 | 2007-2020 | 2016 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 45 | Gerrit Cole | 25 | R | 7 | 10 | 3.88 | 21 | 21 | 1 | 0 | 0 | 0 | 0 | 116.0 | 131 | 57 | 50 | 7 | 36 | 98 | 5 | 1 | 6 | 1.44 | 10.16 | 0.54 | 2.79 | 7.60 | 4.42 | 2.72 | 2011- 1- 1-PIT | premium | premium | premium | MLB | 2013-2024 | 2009-2024 | 2016 |
| 47 | Francisco Liriano | 32 | L | 6 | 11 | 5.46 | 21 | 21 | 0 | 0 | 0 | 0 | 0 | 113.2 | 115 | 76 | 69 | 19 | 69 | 116 | 8 | 0 | 7 | 1.62 | 9.11 | 1.50 | 5.46 | 9.18 | 6.02 | 1.68 | 2000- UDFA -SFN | premium | premium | premium | MLB | 2005-2019 | 2001-2019 | 2016 |
| 18 | Jonathon Niese | 29 | L | 8 | 6 | 4.91 | 23 | 18 | 0 | 0 | 5 | 2 | 0 | 110.0 | 132 | 63 | 60 | 21 | 38 | 76 | 9 | 0 | 3 | 1.55 | 10.80 | 1.72 | 3.11 | 6.22 | 5.15 | 2.00 | 2005- 7- 209-NYN | premium | premium | premium | MLB | 2008-2016 | 2005-2019 | 2016 |
| 34 | Drew Hutchison | 25 | R | 0 | 0 | 5.56 | 6 | 1 | 0 | 0 | 5 | 3 | 0 | 11.1 | 15 | 7 | 7 | 2 | 3 | 10 | 0 | 0 | 1 | 1.59 | 11.91 | 1.59 | 2.38 | 7.94 | 5.56 | 3.33 | 2009- 15- 460-TOR | premium | premium | premium | MLB | 2012-2022 | 2010-2024 | 2016 |
| 50 | Jameson Taillon | 24 | R | 5 | 4 | 3.38 | 18 | 18 | 0 | 0 | 0 | 0 | 0 | 104.0 | 99 | 40 | 39 | 13 | 17 | 85 | 1 | 2 | 3 | 1.12 | 8.57 | 1.13 | 1.47 | 7.36 | 3.46 | 5.00 | 2010- 1- 2-PIT | premium | premium | premium | MLB | 2016-2025 | 2011-2025 | 2016 |
| 38 | Erik Kratz | 36 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.00 | 18.00 | 0.00 | 0.00 | 9.00 | 0.00 | 0.00 | 2002- 29- 866-TOR | premium | premium | premium | MLB | 2010-2020 | 2002-2020 | 2016 |
| 52 | Curtis Partch | 29 | R | 0 | 0 | 40.50 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0.2 | 2 | 3 | 3 | 0 | 2 | 0 | 1 | 0 | 0 | 6.00 | 27.00 | 0.00 | 27.00 | 0.00 | 40.50 | 0.00 | 2007- 26- 799-CIN | premium | premium | premium | MLB | 2013-2016 | 2007-2017 | 2016 |
| Totals: | 78 | 83 | 4.22 | 687 | 162 | 5 | 1 | 157 | 525 | 51 | 1450.2 | 1491 | 758 | 681 | 180 | 533 | 1232 | 71 | 7 | 68 | 1.40 | 9.25 | 1.12 | 3.31 | 7.64 | 4.70 | 2.31 | premium | premium | premium |