| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 17 | Shin-Soo Choo | 27 | RF | L | 121 | 144 | 550 | 81 | 165 | 31 | 2 | 22 | 90 | 22 | 7 | 83 | 118 | 11 | 0 | 2 | 11 | 11 | 266 | 646 | 55 | 110 | .300 | .401 | .484 | .885 | .362 | .184 | .347 | 12.85 | 18.27 | 1.42 | 25.00 | 2000- UDFA -CLE | premium | premium | premium | MLB | 2005-2020 | 2001-2020 | 2010 |
| 4 | Trevor Crowe | 26 | CF-LF | B | 89 | 122 | 442 | 48 | 111 | 24 | 3 | 2 | 36 | 20 | 7 | 29 | 73 | 3 | 5 | 0 | 1 | 13 | 147 | 479 | 29 | 82 | .251 | .302 | .333 | .635 | .176 | .082 | .297 | 6.05 | 15.24 | 2.52 | 221.00 | 2005- 1- 14-CLE | premium | premium | premium | MLB | 2009-2013 | 2003-2014 | 2010 |
| 48 | Travis Hafner | 33 | DH | L | 111 | 118 | 396 | 46 | 110 | 29 | 0 | 13 | 50 | 2 | 1 | 51 | 94 | 12 | 0 | 3 | 10 | 2 | 178 | 462 | 42 | 68 | .278 | .374 | .449 | .823 | .303 | .171 | .332 | 11.04 | 20.35 | 1.84 | 30.46 | 1996- 31- 923-TEX | premium | premium | premium | MLB | 2002-2013 | 1997-2018 | 2010 |
| 13 | Asdrubal Cabrera | 24 | SS | B | 94 | 97 | 381 | 39 | 105 | 16 | 1 | 3 | 29 | 6 | 4 | 25 | 60 | 5 | 11 | 3 | 0 | 10 | 132 | 425 | 20 | 85 | .276 | .326 | .346 | .672 | .142 | .070 | .318 | 5.88 | 14.12 | 2.40 | 127.00 | 2002- UDFA -SEA | premium | premium | premium | MLB | 2007-2021 | 2004-2021 | 2010 |
| 7 | Matt LaPorta | 25 | 1B | R | 93 | 110 | 376 | 41 | 83 | 15 | 1 | 12 | 41 | 0 | 0 | 46 | 82 | 1 | 0 | 2 | 1 | 12 | 136 | 425 | 28 | 55 | .221 | .306 | .362 | .668 | .263 | .141 | .250 | 10.82 | 19.29 | 1.78 | 31.33 | 2007- 1- 7-MIL | premium | premium | premium | MLB | 2009-2012 | 2004-2014 | 2010 |
| 2 | Jhonny Peralta | 28 | 3B | R | 96 | 91 | 334 | 37 | 82 | 23 | 2 | 7 | 43 | 1 | 0 | 32 | 69 | 1 | 0 | 6 | 1 | 7 | 130 | 373 | 32 | 50 | .246 | .308 | .389 | .697 | .243 | .143 | .284 | 8.58 | 18.50 | 2.16 | 47.71 | 1999- UDFA -CLE | premium | premium | premium | MLB | 2003-2017 | 2000-2017 | 2010 |
| 26 | Austin Kearns | 30 | LF | R | 104 | 84 | 301 | 42 | 82 | 18 | 1 | 8 | 42 | 4 | 1 | 34 | 78 | 5 | 0 | 2 | 2 | 12 | 126 | 342 | 27 | 55 | .272 | .354 | .419 | .773 | .269 | .147 | .341 | 9.94 | 22.81 | 2.29 | 37.63 | 1998- 1- 7-CIN | premium | premium | premium | MLB | 2002-2013 | 1998-2013 | 2010 |
| 23 | Michael Brantley | 23 | CF | L | 88 | 72 | 297 | 38 | 73 | 9 | 3 | 3 | 22 | 10 | 2 | 22 | 38 | 0 | 4 | 2 | 0 | 6 | 97 | 325 | 15 | 58 | .246 | .296 | .327 | .623 | .182 | .081 | .271 | 6.77 | 11.69 | 1.73 | 99.00 | 2005- 7- 205-MIL | premium | premium | premium | MLB | 2009-2023 | 2005-2023 | 2010 |
| 16 | Jason Donald | 25 | SS-2B | R | 95 | 88 | 296 | 39 | 75 | 19 | 3 | 4 | 24 | 5 | 1 | 22 | 70 | 3 | 4 | 0 | 2 | 3 | 112 | 325 | 26 | 49 | .253 | .312 | .378 | .690 | .213 | .125 | .320 | 6.77 | 21.54 | 3.18 | 74.00 | 2006- 3- 97-PHI | premium | premium | premium | MLB | 2010-2012 | 2004-2014 | 2010 |
| 12 | Jayson Nix | 27 | 3B-2B | R | 92 | 78 | 282 | 29 | 66 | 14 | 0 | 13 | 29 | 1 | 2 | 13 | 75 | 7 | 2 | 2 | 0 | 5 | 119 | 306 | 27 | 39 | .234 | .283 | .422 | .705 | .230 | .188 | .270 | 4.25 | 24.51 | 5.77 | 21.69 | 2001- 1- 44-COL | premium | premium | premium | MLB | 2008-2014 | 2001-2015 | 2010 |
| 1 | Luis Valbuena | 24 | 2B | L | 76 | 91 | 275 | 22 | 53 | 12 | 0 | 2 | 24 | 1 | 2 | 28 | 61 | 3 | 2 | 2 | 1 | 5 | 71 | 310 | 14 | 39 | .193 | .273 | .258 | .531 | .164 | .065 | .238 | 9.03 | 19.68 | 2.18 | 137.50 | 2002- UDFA -SEA | premium | premium | premium | MLB | 2008-2018 | 2005-2018 | 2010 |
| 30 | Lou Marson | 24 | C | R | 81 | 87 | 262 | 29 | 51 | 15 | 0 | 3 | 22 | 8 | 1 | 26 | 55 | 3 | 2 | 1 | 0 | 7 | 75 | 294 | 18 | 33 | .195 | .274 | .286 | .560 | .218 | .091 | .234 | 8.84 | 18.71 | 2.12 | 87.33 | 2004- 4- 122-PHI | premium | premium | premium | MLB | 2008-2013 | 2004-2015 | 2010 |
| 47 | Shelley Duncan | 30 | LF | R | 101 | 85 | 229 | 29 | 53 | 10 | 0 | 11 | 36 | 1 | 0 | 26 | 76 | 3 | 0 | 1 | 2 | 4 | 96 | 259 | 21 | 32 | .231 | .317 | .419 | .736 | .306 | .188 | .294 | 10.04 | 29.34 | 2.92 | 20.82 | 2001- 2- 62-NYA | premium | premium | premium | MLB | 2007-2013 | 1999-2014 | 2010 |
| 33 | Russell Branyan | 34 | 1B | L | 109 | 52 | 171 | 24 | 45 | 9 | 0 | 10 | 24 | 0 | 0 | 16 | 49 | 1 | 1 | 1 | 1 | 2 | 84 | 190 | 19 | 26 | .263 | .328 | .491 | .819 | .322 | .228 | .310 | 8.42 | 25.79 | 3.06 | 17.10 | 1994- 7- 185-CLE | premium | premium | premium | MLB | 1998-2011 | 1994-2014 | 2010 |
| 25 | Andy Marte | 26 | 3B-1B | R | 92* | 80 | 170 | 18 | 39 | 7 | 2 | 5 | 19 | 0 | 3 | 17 | 35 | 0 | 0 | 1 | 0 | 2 | 65 | 188 | 14 | 25 | .229 | .298 | .382 | .680 | .235 | .153 | .260 | 9.04 | 18.62 | 2.06 | 34.00 | 2000- UDFA -ATL | premium | premium | premium | MLB | 2005-2014 | 2001-2014 | 2010 |
| 41 | Carlos Santana | 24 | C | B | 119* | 46 | 150 | 23 | 39 | 13 | 0 | 6 | 22 | 3 | 0 | 37 | 29 | 1 | 0 | 4 | 2 | 3 | 70 | 192 | 19 | 20 | .260 | .401 | .467 | .868 | .473 | .207 | .277 | 19.27 | 15.10 | 0.78 | 25.00 | 2004- UDFA -LAN | premium | premium | premium | MLB | 2010-2025 | 2005-2025 | 2010 |
| 24 | Grady Sizemore | 27 | CF | L | 79* | 33 | 128 | 15 | 27 | 6 | 2 | 0 | 13 | 4 | 2 | 9 | 35 | 2 | 0 | 1 | 0 | 1 | 37 | 140 | 8 | 19 | .211 | .271 | .289 | .560 | .164 | .078 | .287 | 6.43 | 25.00 | 3.89 | 0.00 | 2000- 3- 75-MON | premium | premium | premium | MLB | 2004-2015 | 2000-2015 | 2010 |
| 12 | Mark Grudzielanek | 40 | 2B | R | 87* | 30 | 110 | 10 | 30 | 0 | 0 | 0 | 11 | 2 | 0 | 8 | 10 | 1 | 0 | 0 | 0 | 4 | 30 | 119 | 0 | 30 | .273 | .328 | .273 | .601 | .091 | .000 | .300 | 6.72 | 8.40 | 1.25 | 0.00 | 1991- 11- 295-MON | premium | premium | premium | MLB | 1995-2010 | 1991-2010 | 2010 |
| 35 | Jordan Brown | 26 | 1B-LF | L | 26 | 87 | 9 | 20 | 7 | 0 | 0 | 2 | 0 | 0 | 4 | 10 | 1 | 0 | 0 | 0 | 3 | 27 | 92 | 7 | 13 | .230 | .272 | .310 | .582 | .126 | .080 | .260 | 4.35 | 10.87 | 2.50 | 0.00 | 2005- 4- 124-CLE | premium | premium | premium | MLB | 2010-2013 | 2003-2014 | 2010 | |
| 52 | Mike Redmond | 39 | C | R | 22 | 63 | 7 | 13 | 4 | 0 | 0 | 5 | 0 | 0 | 2 | 10 | 1 | 2 | 0 | 0 | 2 | 17 | 68 | 4 | 9 | .206 | .242 | .270 | .512 | .095 | .064 | .245 | 2.94 | 14.71 | 5.00 | 0.00 | 1992- UDFA -MIA | premium | premium | premium | MLB | 1998-2010 | 1990-2010 | 2010 | |
| 20 | Anderson Hernandez | 27 | SS | B | 81* | 22 | 61 | 6 | 15 | 3 | 0 | 0 | 2 | 1 | 0 | 2 | 9 | 0 | 0 | 0 | 0 | 2 | 18 | 63 | 3 | 12 | .246 | .270 | .295 | .565 | .098 | .049 | .288 | 3.17 | 14.29 | 4.50 | 0.00 | 2001- UDFA -DET | premium | premium | premium | MLB | 2005-2010 | 2001-2018 | 2010 |
| 8 | Chris Gimenez | 27 | C | R | 28 | 58 | 6 | 11 | 5 | 0 | 1 | 8 | 0 | 0 | 8 | 22 | 0 | 1 | 0 | 0 | 1 | 19 | 67 | 6 | 5 | .190 | .288 | .328 | .616 | .276 | .138 | .286 | 11.94 | 32.84 | 2.75 | 58.00 | 2004- 19- 557-CLE | premium | premium | premium | MLB | 2009-2018 | 2002-2018 | 2010 | |
| 33 | Drew Sutton | 27 | SS-2B | B | 11 | 36 | 4 | 8 | 1 | 0 | 1 | 4 | 0 | 0 | 3 | 12 | 0 | 0 | 0 | 0 | 1 | 12 | 39 | 2 | 6 | .222 | .282 | .333 | .615 | .194 | .111 | .304 | 7.69 | 30.77 | 4.00 | 36.00 | 2004- 15- 454-HOU | premium | premium | premium | MLB | 2009-2012 | 2004-2013 | 2010 | |
| 26 | Luke Carlin | 29 | C | B | 6 | 14 | 4 | 5 | 0 | 0 | 2 | 3 | 0 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 11 | 16 | 2 | 3 | .357 | .438 | .786 | 1.224 | .571 | .429 | .429 | 12.50 | 31.25 | 2.50 | 7.00 | 2002- 10- 290-DET | premium | premium | premium | MLB | 2008-2012 | 2000-2015 | 2010 | |
| 51 | Mitch Talbot | 26 | P | R | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 80.00 | 0.00 | 0.00 | 2002- 2- 70-HOU | premium | premium | premium | MLB | 2008-2011 | 2003-2019 | 2010 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 55 | Roberto Hernandez | 29 | P | R | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 40.00 | 0.00 | 0.00 | 2000- UDFA -CLE | premium | premium | premium | MLB | 2006-2016 | 2002-2016 | 2010 | |
| 63 | Justin Masterson | 25 | P | R | 2 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 5 | 0 | 1 | .250 | .250 | .250 | .500 | .000 | .000 | .333 | 0.00 | 20.00 | 0.00 | 0.00 | 2006- 2- 71-BOS | premium | premium | premium | MLB | 2008-2015 | 2006-2017 | 2010 | |
| 28 | David Huff | 25 | P | B | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2006- 1- 39-CLE | premium | premium | premium | MLB | 2009-2016 | 2004-2024 | 2010 | |
| 37 | Jake Westbrook | 32 | P | R | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 1996- 1- 21-COL | premium | premium | premium | MLB | 2000-2013 | 1996-2013 | 2010 | |
| 32 | Aaron Laffey | 25 | P | L | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2003- 16- 468-CLE | premium | premium | premium | MLB | 2007-2015 | 2003-2018 | 2010 | |
| Totals: | 1632 | 5487 | 646 | 1362 | 290 | 20 | 128 | 601 | 91 | 33 | 545 | 1184 | 64 | 36 | 33 | 34 | 118 | 2076 | 6165 | 438 | 924 | .248 | .322 | .378 | .700 | .240 | .130 | .293 | 8.84 | 19.21 | 2.17 | 42.87 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 28 | David Huff | 25 | L | 2 | 11 | 6.21 | 15 | 15 | 1 | 0 | 0 | 0 | 0 | 79.2 | 101 | 61 | 55 | 14 | 34 | 37 | 2 | 0 | 3 | 1.69 | 11.41 | 1.58 | 3.84 | 4.18 | 6.89 | 1.09 | 2006- 1- 39-CLE | premium | premium | premium | MLB | 2009-2016 | 2004-2024 | 2010 |
| 43 | Josh Tomlin | 25 | R | 6 | 4 | 4.56 | 12 | 12 | 1 | 0 | 0 | 0 | 0 | 73.0 | 72 | 38 | 37 | 10 | 19 | 43 | 1 | 0 | 3 | 1.25 | 8.88 | 1.23 | 2.34 | 5.30 | 4.68 | 2.26 | 2006- 19- 581-CLE | premium | premium | premium | MLB | 2010-2021 | 2006-2021 | 2010 |
| 46 | Tony Sipp | 26 | L | 2 | 2 | 4.14 | 70 | 0 | 0 | 0 | 70 | 16 | 1 | 63.0 | 48 | 30 | 29 | 12 | 39 | 69 | 4 | 0 | 2 | 1.38 | 6.86 | 1.71 | 5.57 | 9.86 | 4.29 | 1.77 | 2004- 45-1333-CLE | premium | premium | premium | MLB | 2009-2019 | 2004-2019 | 2010 |
| 54 | Chris Perez | 24 | R | 2 | 2 | 1.71 | 63 | 0 | 0 | 0 | 63 | 37 | 23 | 63.0 | 40 | 15 | 12 | 4 | 28 | 61 | 4 | 0 | 5 | 1.08 | 5.71 | 0.57 | 4.00 | 8.71 | 2.14 | 2.18 | 2006- 1- 42-SLN | premium | premium | premium | MLB | 2008-2014 | 2004-2015 | 2010 |
| 53 | Rafael Perez | 28 | L | 6 | 1 | 3.25 | 70 | 0 | 0 | 0 | 70 | 13 | 0 | 61.0 | 72 | 23 | 22 | 3 | 25 | 36 | 6 | 0 | 0 | 1.59 | 10.62 | 0.44 | 3.69 | 5.31 | 3.39 | 1.44 | 2002- UDFA -CLE | premium | premium | premium | MLB | 2006-2012 | 2003-2017 | 2010 |
| 40 | Jess Todd | 24 | R | 0 | 0 | 7.50 | 5 | 0 | 0 | 0 | 5 | 2 | 0 | 6.0 | 9 | 5 | 5 | 0 | 3 | 9 | 1 | 0 | 0 | 2.00 | 13.50 | 0.00 | 4.50 | 13.50 | 7.50 | 3.00 | 2007- 2- 82-SLN | premium | premium | premium | MLB | 2009-2010 | 2007-2015 | 2010 |
| 58 | Jeanmar Gomez | 22 | R | 4 | 5 | 4.68 | 11 | 11 | 0 | 0 | 0 | 0 | 0 | 57.2 | 73 | 36 | 30 | 7 | 22 | 34 | 1 | 0 | 2 | 1.65 | 11.39 | 1.09 | 3.43 | 5.31 | 5.62 | 1.55 | 2005- UDFA -CLE | premium | premium | premium | MLB | 2010-2019 | 2006-2019 | 2010 |
| 32 | Aaron Laffey | 25 | L | 2 | 3 | 4.53 | 29 | 5 | 0 | 0 | 24 | 1 | 0 | 55.2 | 62 | 30 | 28 | 1 | 28 | 28 | 1 | 0 | 2 | 1.62 | 10.02 | 0.16 | 4.53 | 4.53 | 4.85 | 1.00 | 2003- 16- 468-CLE | premium | premium | premium | MLB | 2007-2015 | 2003-2018 | 2010 |
| 52 | Vinnie Pestano | 25 | R | 0 | 0 | 3.60 | 5 | 0 | 0 | 0 | 5 | 5 | 1 | 5.0 | 4 | 2 | 2 | 0 | 5 | 8 | 0 | 0 | 0 | 1.80 | 7.20 | 0.00 | 9.00 | 14.40 | 3.60 | 1.60 | 2006- 20- 611-CLE | premium | premium | premium | MLB | 2010-2015 | 2004-2018 | 2010 |
| 57 | Hector Ambriz | 26 | R | 0 | 2 | 5.59 | 34 | 0 | 0 | 0 | 34 | 20 | 0 | 48.1 | 68 | 31 | 30 | 10 | 17 | 37 | 4 | 0 | 1 | 1.76 | 12.66 | 1.86 | 3.17 | 6.89 | 5.77 | 2.18 | 2006- 5- 147-ARI | premium | premium | premium | MLB | 2010-2014 | 2003-2019 | 2010 |
| 59 | Carlos Carrasco | 23 | R | 2 | 2 | 3.83 | 7 | 7 | 1 | 0 | 0 | 0 | 0 | 44.2 | 47 | 20 | 19 | 6 | 14 | 38 | 1 | 0 | 1 | 1.37 | 9.47 | 1.21 | 2.82 | 7.66 | 4.03 | 2.71 | 2003- UDFA -PHI | premium | premium | premium | MLB | 2009-2025 | 2004-2025 | 2010 |
| 56 | Frank Herrmann | 26 | R | 0 | 1 | 4.03 | 40 | 0 | 0 | 0 | 40 | 8 | 1 | 44.2 | 48 | 22 | 20 | 6 | 9 | 24 | 2 | 0 | 2 | 1.28 | 9.67 | 1.21 | 1.81 | 4.84 | 4.43 | 2.67 | 2005- UDFA -CLE | premium | premium | premium | MLB | 2010-2016 | 2003-2021 | 2010 |
| 38 | Joe Smith | 26 | R | 2 | 2 | 3.83 | 53 | 0 | 0 | 0 | 53 | 7 | 0 | 40.0 | 30 | 18 | 17 | 4 | 24 | 32 | 0 | 1 | 1 | 1.35 | 6.75 | 0.90 | 5.40 | 7.20 | 4.05 | 1.33 | 2006- 3- 94-NYN | premium | premium | premium | MLB | 2007-2022 | 2004-2022 | 2010 |
| 50 | Jensen Lewis | 26 | R | 4 | 2 | 2.97 | 37 | 0 | 0 | 0 | 37 | 11 | 0 | 36.1 | 28 | 12 | 12 | 1 | 19 | 29 | 0 | 0 | 0 | 1.29 | 6.94 | 0.25 | 4.71 | 7.18 | 2.97 | 1.53 | 2005- 3- 102-CLE | premium | premium | premium | MLB | 2007-2010 | 2003-2013 | 2010 |
| 39 | Justin Germano | 27 | R | 0 | 3 | 3.31 | 23 | 1 | 0 | 0 | 22 | 4 | 0 | 35.1 | 27 | 15 | 13 | 6 | 8 | 29 | 0 | 0 | 6 | 0.99 | 6.88 | 1.53 | 2.04 | 7.39 | 3.82 | 3.63 | 2000- 13- 379-SDN | premium | premium | premium | MLB | 2004-2014 | 2000-2015 | 2010 |
| 55 | Roberto Hernandez | 29 | R | 13 | 14 | 3.77 | 33 | 33 | 4 | 1 | 0 | 0 | 0 | 210.1 | 203 | 98 | 88 | 17 | 72 | 124 | 3 | 0 | 9 | 1.31 | 8.69 | 0.73 | 3.08 | 5.31 | 4.19 | 1.72 | 2000- UDFA -CLE | premium | premium | premium | MLB | 2006-2016 | 2002-2016 | 2010 |
| 31 | Jamey Wright | 35 | R | 1 | 2 | 5.48 | 18 | 0 | 0 | 0 | 18 | 9 | 0 | 21.1 | 25 | 18 | 13 | 1 | 9 | 9 | 1 | 0 | 2 | 1.59 | 10.55 | 0.42 | 3.80 | 3.80 | 7.59 | 1.00 | 1993- 1- 28-COL | premium | premium | premium | MLB | 1996-2014 | 1993-2014 | 2010 |
| 34 | Kerry Wood | 33 | R | 1 | 4 | 6.30 | 23 | 0 | 0 | 0 | 23 | 18 | 8 | 20.0 | 21 | 15 | 14 | 3 | 11 | 18 | 2 | 1 | 2 | 1.60 | 9.45 | 1.35 | 4.95 | 8.10 | 6.75 | 1.64 | 1995- 1- 4-CHN | premium | premium | premium | MLB | 1998-2012 | 1995-2012 | 2010 |
| 63 | Justin Masterson | 25 | R | 6 | 13 | 4.70 | 34 | 29 | 1 | 1 | 5 | 0 | 0 | 180.0 | 197 | 107 | 94 | 14 | 73 | 140 | 12 | 0 | 11 | 1.50 | 9.85 | 0.70 | 3.65 | 7.00 | 5.35 | 1.92 | 2006- 2- 71-BOS | premium | premium | premium | MLB | 2008-2015 | 2006-2017 | 2010 |
| 51 | Mitch Talbot | 26 | R | 10 | 13 | 4.41 | 28 | 28 | 1 | 0 | 0 | 0 | 0 | 159.1 | 169 | 88 | 78 | 13 | 69 | 88 | 3 | 1 | 8 | 1.49 | 9.55 | 0.73 | 3.90 | 4.97 | 4.97 | 1.28 | 2002- 2- 70-HOU | premium | premium | premium | MLB | 2008-2011 | 2003-2019 | 2010 |
| 37 | Jake Westbrook | 32 | R | 6 | 7 | 4.65 | 21 | 21 | 1 | 0 | 0 | 0 | 0 | 127.2 | 133 | 68 | 66 | 15 | 44 | 73 | 6 | 0 | 6 | 1.39 | 9.38 | 1.06 | 3.10 | 5.15 | 4.79 | 1.66 | 1996- 1- 21-COL | premium | premium | premium | MLB | 2000-2013 | 1996-2013 | 2010 |
| 25 | Andy Marte | 26 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 9.00 | 0.00 | 0.00 | 2000- UDFA -ATL | premium | premium | premium | MLB | 2005-2014 | 2001-2014 | 2010 |
| Totals: | 69 | 93 | 4.30 | 632 | 162 | 10 | 2 | 152 | 470 | 34 | 1433.0 | 1477 | 752 | 684 | 147 | 572 | 967 | 54 | 3 | 66 | 1.43 | 9.28 | 0.92 | 3.59 | 6.07 | 4.72 | 1.69 | premium | premium | premium |