| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 7 | Matt Holliday | 30 | LF | R | 124 | 158 | 596 | 95 | 186 | 45 | 1 | 28 | 103 | 9 | 5 | 69 | 93 | 8 | 0 | 2 | 10 | 13 | 317 | 675 | 74 | 112 | .312 | .390 | .532 | .922 | .342 | .220 | .331 | 10.22 | 13.78 | 1.35 | 21.29 | 1998- 7- 210-COL | premium | premium | premium | MLB | 2004-2018 | 1998-2018 | 2010 |
| 5 | Albert Pujols | 30 | 1B | R | 131 | 159 | 587 | 115 | 183 | 39 | 1 | 42 | 118 | 14 | 4 | 103 | 76 | 4 | 0 | 6 | 38 | 23 | 350 | 700 | 82 | 101 | .312 | .414 | .596 | 1.010 | .477 | .284 | .297 | 14.71 | 10.86 | 0.74 | 13.98 | 1999- 13- 402-SLN | premium | premium | premium | MLB | 2001-2022 | 2000-2022 | 2010 |
| 55 | Skip Schumaker | 30 | 2B | L | 93 | 137 | 476 | 66 | 126 | 18 | 1 | 5 | 42 | 5 | 3 | 43 | 64 | 4 | 2 | 4 | 2 | 7 | 161 | 529 | 24 | 102 | .265 | .328 | .338 | .666 | .168 | .073 | .294 | 8.13 | 12.10 | 1.49 | 95.20 | 2001- 5- 164-SLN | premium | premium | premium | MLB | 2005-2015 | 1999-2015 | 2010 |
| 4 | Yadier Molina | 27 | C | R | 93 | 136 | 465 | 34 | 122 | 19 | 0 | 6 | 62 | 8 | 4 | 42 | 51 | 7 | 2 | 5 | 6 | 19 | 159 | 521 | 25 | 97 | .262 | .329 | .342 | .671 | .178 | .080 | .281 | 8.06 | 9.79 | 1.21 | 77.50 | 2000- 4- 113-SLN | premium | premium | premium | MLB | 2004-2022 | 2001-2022 | 2010 |
| 28 | Colby Rasmus | 23 | CF | L | 114 | 144 | 464 | 85 | 128 | 28 | 3 | 23 | 66 | 12 | 8 | 63 | 148 | 1 | 2 | 4 | 9 | 5 | 231 | 534 | 54 | 74 | .276 | .361 | .498 | .859 | .366 | .222 | .354 | 11.80 | 27.72 | 2.35 | 20.17 | 2005- 1- 28-SLN | premium | premium | premium | MLB | 2009-2018 | 2005-2018 | 2010 |
| 13 | Brendan Ryan | 28 | SS | R | 80 | 139 | 439 | 50 | 98 | 19 | 3 | 2 | 36 | 11 | 4 | 33 | 60 | 2 | 9 | 3 | 5 | 6 | 129 | 486 | 24 | 74 | .223 | .279 | .294 | .573 | .162 | .071 | .253 | 6.79 | 12.35 | 1.82 | 219.50 | 2003- 7- 215-SLN | premium | premium | premium | MLB | 2007-2016 | 2003-2017 | 2010 |
| 3 | Felipe Lopez | 30 | 3B | B | 92 | 109 | 376 | 50 | 87 | 18 | 1 | 7 | 36 | 8 | 2 | 43 | 77 | 1 | 3 | 2 | 1 | 7 | 128 | 425 | 26 | 61 | .231 | .310 | .340 | .650 | .239 | .109 | .272 | 10.12 | 18.12 | 1.79 | 53.71 | 1998- 1- 8-TOR | premium | premium | premium | MLB | 2001-2011 | 1998-2011 | 2010 |
| 15 | Jon Jay | 25 | RF | L | 106 | 105 | 287 | 47 | 86 | 19 | 2 | 4 | 27 | 2 | 4 | 24 | 50 | 3 | 8 | 1 | 0 | 5 | 121 | 323 | 25 | 61 | .300 | .359 | .422 | .781 | .199 | .122 | .350 | 7.43 | 15.48 | 2.08 | 71.75 | 2006- 2- 74-SLN | premium | premium | premium | MLB | 2010-2021 | 2004-2021 | 2010 |
| 47 | Ryan Ludwick | 31 | RF | R | 101 | 77 | 281 | 44 | 79 | 20 | 2 | 11 | 43 | 0 | 3 | 24 | 64 | 4 | 0 | 3 | 0 | 4 | 136 | 312 | 33 | 46 | .281 | .343 | .484 | .827 | .278 | .203 | .325 | 7.69 | 20.51 | 2.67 | 25.55 | 1999- 2- 60-OAK | premium | premium | premium | MLB | 2002-2014 | 1997-2014 | 2010 |
| 23 | David Freese | 27 | 3B | R | 106 | 70 | 240 | 28 | 71 | 12 | 1 | 4 | 36 | 1 | 1 | 21 | 59 | 4 | 4 | 1 | 0 | 7 | 97 | 270 | 17 | 54 | .296 | .361 | .404 | .765 | .196 | .108 | .376 | 7.78 | 21.85 | 2.81 | 60.00 | 2006- 9- 273-SDN | premium | premium | premium | MLB | 2009-2019 | 2005-2019 | 2010 |
| 44 | Randy Winn | 36 | RF | B | 93 | 87 | 144 | 16 | 36 | 8 | 1 | 3 | 17 | 5 | 0 | 13 | 22 | 1 | 1 | 3 | 1 | 4 | 55 | 162 | 12 | 24 | .250 | .311 | .382 | .693 | .257 | .132 | .270 | 8.02 | 13.58 | 1.69 | 48.00 | 1995- 3- 65-MIA | premium | premium | premium | MLB | 1998-2010 | 1994-2010 | 2010 |
| 12 | Aaron Miles | 33 | 2B | B | 86* | 79 | 139 | 14 | 39 | 5 | 0 | 0 | 9 | 0 | 1 | 6 | 14 | 1 | 3 | 2 | 1 | 1 | 44 | 151 | 5 | 34 | .281 | .311 | .317 | .628 | .072 | .036 | .307 | 3.97 | 9.27 | 2.33 | 0.00 | 1995- 19- 529-HOU | premium | premium | premium | MLB | 2003-2011 | 1995-2016 | 2010 |
| 34 | Nick Stavinoha | 28 | RF | R | 87* | 79 | 121 | 11 | 31 | 4 | 0 | 2 | 9 | 0 | 0 | 4 | 28 | 1 | 0 | 0 | 0 | 5 | 41 | 126 | 6 | 25 | .256 | .286 | .339 | .625 | .116 | .083 | .319 | 3.17 | 22.22 | 7.00 | 60.50 | 2005- 7- 230-SLN | premium | premium | premium | MLB | 2008-2010 | 2004-2014 | 2010 |
| 77 | Pedro Feliz | 35 | 3B | R | 73 | 40 | 120 | 14 | 25 | 0 | 1 | 1 | 9 | 0 | 0 | 4 | 10 | 0 | 0 | 1 | 0 | 4 | 30 | 125 | 2 | 23 | .208 | .232 | .250 | .482 | .075 | .042 | .218 | 3.20 | 8.00 | 2.50 | 120.00 | 1994- UDFA -SFN | premium | premium | premium | MLB | 2000-2010 | 1998-2012 | 2010 |
| 8 | Allen Craig | 25 | RF | R | 95* | 44 | 114 | 12 | 28 | 7 | 0 | 4 | 18 | 0 | 1 | 9 | 26 | 0 | 0 | 1 | 1 | 1 | 47 | 124 | 11 | 17 | .246 | .298 | .412 | .710 | .237 | .166 | .282 | 7.26 | 20.97 | 2.89 | 28.50 | 2006- 8- 256-SLN | premium | premium | premium | MLB | 2010-2015 | 2003-2018 | 2010 |
| 27 | Tyler Greene | 26 | SS-2B | R | 91* | 44 | 104 | 14 | 23 | 3 | 1 | 2 | 10 | 2 | 0 | 13 | 24 | 4 | 0 | 1 | 4 | 1 | 34 | 122 | 6 | 17 | .221 | .328 | .327 | .655 | .250 | .106 | .266 | 10.66 | 19.67 | 1.85 | 52.00 | 2005- 1- 30-SLN | premium | premium | premium | MLB | 2009-2013 | 2003-2014 | 2010 |
| 50 | Adam Wainwright | 28 | P | R | 36 | 84 | 4 | 14 | 5 | 0 | 0 | 6 | 0 | 0 | 7 | 23 | 0 | 5 | 0 | 0 | 2 | 19 | 96 | 5 | 9 | .167 | .231 | .226 | .457 | .143 | .059 | .230 | 7.29 | 23.96 | 3.29 | 0.00 | 2000- 1- 29-ATL | premium | premium | premium | MLB | 2005-2023 | 2000-2023 | 2010 | |
| 29 | Chris Carpenter | 35 | P | R | 34 | 72 | 2 | 8 | 0 | 0 | 1 | 4 | 0 | 0 | 1 | 25 | 1 | 10 | 0 | 0 | 2 | 11 | 84 | 1 | 7 | .111 | .135 | .153 | .288 | .056 | .042 | .152 | 1.19 | 29.76 | 25.00 | 72.00 | 1993- 1- 15-TOR | premium | premium | premium | MLB | 1997-2012 | 1994-2013 | 2010 | |
| 22 | Joe Mather | 27 | CF-RF | R | 36 | 60 | 7 | 13 | 4 | 0 | 0 | 3 | 1 | 1 | 2 | 11 | 0 | 2 | 0 | 0 | 2 | 17 | 64 | 4 | 9 | .217 | .242 | .283 | .525 | .100 | .066 | .265 | 3.13 | 17.19 | 5.50 | 0.00 | 2001- 3- 104-SLN | premium | premium | premium | MLB | 2008-2012 | 2001-2014 | 2010 | |
| 21 | Jason LaRue | 36 | C | R | 29 | 56 | 3 | 11 | 1 | 0 | 2 | 5 | 0 | 0 | 5 | 7 | 1 | 1 | 0 | 0 | 3 | 18 | 63 | 3 | 8 | .196 | .274 | .321 | .595 | .214 | .125 | .191 | 7.94 | 11.11 | 1.40 | 28.00 | 1995- 5- 139-CIN | premium | premium | premium | MLB | 1999-2010 | 1995-2010 | 2010 | |
| 54 | Jaime Garcia | 23 | P | L | 29 | 54 | 8 | 10 | 1 | 0 | 0 | 2 | 0 | 0 | 2 | 13 | 0 | 4 | 0 | 0 | 1 | 11 | 60 | 1 | 9 | .185 | .214 | .204 | .418 | .056 | .019 | .244 | 3.33 | 21.67 | 6.50 | 0.00 | 2005- 22- 680-SLN | premium | premium | premium | MLB | 2008-2018 | 2006-2018 | 2010 | |
| 19 | Matt Pagnozzi | 27 | C | R | 15 | 39 | 4 | 14 | 2 | 0 | 1 | 10 | 0 | 0 | 2 | 8 | 1 | 2 | 0 | 0 | 1 | 19 | 44 | 3 | 11 | .359 | .405 | .487 | .892 | .179 | .128 | .433 | 4.55 | 18.18 | 4.00 | 39.00 | 2003- 8- 245-SLN | premium | premium | premium | MLB | 2009-2014 | 2003-2015 | 2010 | |
| 26 | Kyle Lohse | 31 | P | R | 21 | 35 | 2 | 6 | 2 | 0 | 0 | 3 | 0 | 0 | 0 | 8 | 0 | 2 | 0 | 0 | 0 | 8 | 37 | 2 | 4 | .171 | .171 | .229 | .400 | .057 | .058 | .222 | 0.00 | 21.62 | 0.00 | 0.00 | 1996- 29- 862-CHN | premium | premium | premium | MLB | 2001-2016 | 1997-2018 | 2010 | |
| 63 | Daniel Descalso | 23 | 3B | L | 11 | 34 | 6 | 9 | 2 | 0 | 0 | 4 | 1 | 0 | 2 | 6 | 1 | 0 | 0 | 0 | 0 | 11 | 37 | 2 | 7 | .265 | .324 | .324 | .648 | .147 | .059 | .321 | 5.41 | 16.22 | 3.00 | 0.00 | 2007- 3- 112-SLN | premium | premium | premium | MLB | 2010-2019 | 2005-2021 | 2010 | |
| 16 | Bryan Anderson | 23 | C | L | 15 | 32 | 1 | 9 | 2 | 0 | 0 | 4 | 0 | 0 | 1 | 7 | 1 | 0 | 1 | 0 | 0 | 11 | 35 | 2 | 7 | .281 | .314 | .344 | .658 | .094 | .063 | .346 | 2.86 | 20.00 | 7.00 | 0.00 | 2005- 4- 140-SLN | premium | premium | premium | MLB | 2010-2015 | 2005-2016 | 2010 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 35 | Jake Westbrook | 32 | P | R | 12 | 25 | 1 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 11 | 0 | 1 | 0 | 0 | 0 | 4 | 27 | 1 | 2 | .120 | .154 | .160 | .314 | .080 | .040 | .214 | 3.70 | 40.74 | 11.00 | 0.00 | 1996- 1- 21-COL | premium | premium | premium | MLB | 2000-2013 | 1996-2013 | 2010 | |
| 37 | Jeff Suppan | 35 | P | R | 14 | 21 | 1 | 4 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 5 | 0 | 1 | 0 | 0 | 0 | 5 | 23 | 1 | 3 | .190 | .227 | .238 | .465 | .095 | .048 | .250 | 4.35 | 21.74 | 5.00 | 0.00 | 1993- 2- 49-BOS | premium | premium | premium | MLB | 1995-2012 | 1993-2012 | 2010 | |
| 33 | Brad Penny | 32 | P | R | 9 | 19 | 1 | 3 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 6 | 0 | 1 | 0 | 0 | 1 | 6 | 20 | 1 | 2 | .158 | .158 | .316 | .474 | .158 | .158 | .167 | 0.00 | 30.00 | 0.00 | 19.00 | 1996- 5- 155-ARI | premium | premium | premium | MLB | 2000-2014 | 1996-2015 | 2010 | |
| 53 | Blake Hawksworth | 27 | P | R | 44 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 0 | 2 | 0 | 0 | 0 | 0 | 18 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2001- 28- 854-SLN | premium | premium | premium | MLB | 2009-2011 | 2002-2012 | 2010 | |
| 64 | Mark Hamilton | 25 | 1B | L | 9 | 14 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 2 | 15 | 0 | 2 | .143 | .200 | .143 | .343 | .071 | .000 | .222 | 6.67 | 33.33 | 5.00 | 0.00 | 2006- 2- 76-SLN | premium | premium | premium | MLB | 2010-2011 | 2004-2014 | 2010 | |
| 40 | P.J. Walters | 25 | P | R | 7 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | .000 | .125 | .000 | .125 | .143 | .000 | .000 | 11.11 | 55.56 | 5.00 | 0.00 | 2006- 11- 346-SLN | premium | premium | premium | MLB | 2009-2013 | 2004-2015 | 2010 | |
| 35 | Adam Ottavino | 24 | P | B | 5 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | .000 | .143 | .000 | .143 | .167 | .000 | .000 | 14.29 | 71.43 | 5.00 | 0.00 | 2006- 1- 30-SLN | premium | premium | premium | MLB | 2010-2025 | 2004-2025 | 2010 | |
| 31 | Ryan Franklin | 37 | P | R | 57 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1992- 23- 642-SEA | premium | premium | premium | MLB | 1999-2011 | 1993-2011 | 2010 | |
| 41 | Mitchell Boggs | 26 | P | R | 58 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 2005- 5- 170-SLN | premium | premium | premium | MLB | 2008-2013 | 2003-2015 | 2010 | |
| 60 | Steven Hill | 25 | C | R | 1 | 3 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 0 | .333 | .333 | 1.333 | 1.666 | 1.000 | 1.000 | .000 | 0.00 | 33.33 | 0.00 | 3.00 | 2007- 13- 412-SLN | premium | premium | premium | MLB | 2010-2012 | 2006-2012 | 2010 | |
| 36 | Dennys Reyes | 33 | P | R | 56 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1993- UDFA -LAN | premium | premium | premium | MLB | 1997-2011 | 1994-2015 | 2010 | |
| 46 | Kyle McClellan | 26 | P | R | 67 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | .500 | .500 | .500 | 1.000 | .000 | .000 | .500 | 0.00 | 0.00 | 0.00 | 0.00 | 2002- 25- 762-SLN | premium | premium | premium | MLB | 2008-2013 | 2002-2013 | 2010 | |
| 30 | Jason Motte | 28 | P | R | 55 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2003- 19- 575-SLN | premium | premium | premium | MLB | 2008-2017 | 2002-2017 | 2010 | |
| Totals: | 2227 | 5542 | 736 | 1456 | 285 | 18 | 150 | 689 | 79 | 41 | 541 | 1027 | 50 | 66 | 40 | 78 | 124 | 2227 | 6239 | 453 | 1003 | .263 | .332 | .402 | .733 | .244 | .139 | .296 | 8.67 | 16.46 | 1.90 | 36.95 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 26 | Kyle Lohse | 31 | R | 4 | 8 | 6.55 | 18 | 18 | 0 | 0 | 0 | 0 | 0 | 92.0 | 129 | 75 | 67 | 9 | 35 | 54 | 1 | 0 | 3 | 1.78 | 12.62 | 0.88 | 3.42 | 5.28 | 7.34 | 1.54 | 1996- 29- 862-CHN | premium | premium | premium | MLB | 2001-2016 | 1997-2018 | 2010 |
| 53 | Blake Hawksworth | 27 | R | 4 | 8 | 4.98 | 45 | 8 | 0 | 0 | 37 | 9 | 0 | 90.1 | 113 | 56 | 50 | 15 | 35 | 61 | 1 | 3 | 2 | 1.64 | 11.26 | 1.49 | 3.49 | 6.08 | 5.58 | 1.74 | 2001- 28- 854-SLN | premium | premium | premium | MLB | 2009-2011 | 2002-2012 | 2010 |
| 46 | Kyle McClellan | 26 | R | 1 | 4 | 2.27 | 68 | 0 | 0 | 0 | 68 | 18 | 2 | 75.1 | 58 | 20 | 19 | 9 | 23 | 60 | 2 | 0 | 3 | 1.08 | 6.93 | 1.08 | 2.75 | 7.17 | 2.39 | 2.61 | 2002- 25- 762-SLN | premium | premium | premium | MLB | 2008-2013 | 2002-2013 | 2010 |
| 35 | Jake Westbrook | 32 | R | 4 | 4 | 3.48 | 12 | 12 | 0 | 0 | 0 | 0 | 0 | 75.0 | 70 | 31 | 29 | 5 | 24 | 55 | 2 | 0 | 2 | 1.25 | 8.40 | 0.60 | 2.88 | 6.60 | 3.72 | 2.29 | 1996- 1- 21-COL | premium | premium | premium | MLB | 2000-2013 | 1996-2013 | 2010 |
| 37 | Jeff Suppan | 35 | R | 3 | 6 | 3.84 | 15 | 13 | 0 | 0 | 2 | 1 | 0 | 70.1 | 80 | 32 | 30 | 9 | 25 | 33 | 3 | 0 | 1 | 1.49 | 10.24 | 1.15 | 3.20 | 4.22 | 4.09 | 1.32 | 1993- 2- 49-BOS | premium | premium | premium | MLB | 1995-2012 | 1993-2012 | 2010 |
| 41 | Mitchell Boggs | 26 | R | 2 | 3 | 3.61 | 61 | 0 | 0 | 0 | 61 | 22 | 0 | 67.1 | 60 | 29 | 27 | 5 | 27 | 52 | 5 | 0 | 4 | 1.29 | 8.02 | 0.67 | 3.61 | 6.95 | 3.88 | 1.93 | 2005- 5- 170-SLN | premium | premium | premium | MLB | 2008-2013 | 2003-2015 | 2010 |
| 31 | Ryan Franklin | 37 | R | 6 | 2 | 3.46 | 59 | 0 | 0 | 0 | 59 | 51 | 27 | 65.0 | 57 | 25 | 25 | 7 | 10 | 42 | 5 | 0 | 4 | 1.03 | 7.89 | 0.97 | 1.38 | 5.82 | 3.46 | 4.20 | 1992- 23- 642-SEA | premium | premium | premium | MLB | 1999-2011 | 1993-2011 | 2010 |
| 33 | Brad Penny | 32 | R | 3 | 4 | 3.23 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 55.2 | 63 | 25 | 20 | 4 | 9 | 35 | 1 | 0 | 3 | 1.29 | 10.19 | 0.65 | 1.46 | 5.66 | 4.04 | 3.89 | 1996- 5- 155-ARI | premium | premium | premium | MLB | 2000-2014 | 1996-2015 | 2010 |
| 30 | Jason Motte | 28 | R | 4 | 2 | 2.24 | 56 | 0 | 0 | 0 | 56 | 13 | 2 | 52.1 | 41 | 13 | 13 | 5 | 18 | 54 | 1 | 0 | 0 | 1.13 | 7.05 | 0.86 | 3.10 | 9.29 | 2.24 | 3.00 | 2003- 19- 575-SLN | premium | premium | premium | MLB | 2008-2017 | 2002-2017 | 2010 |
| 36 | Dennys Reyes | 33 | L | 3 | 1 | 3.55 | 59 | 0 | 0 | 0 | 59 | 13 | 1 | 38.0 | 34 | 15 | 15 | 2 | 21 | 25 | 4 | 0 | 2 | 1.45 | 8.05 | 0.47 | 4.97 | 5.92 | 3.55 | 1.19 | 1993- UDFA -LAN | premium | premium | premium | MLB | 1997-2011 | 1994-2015 | 2010 |
| 43 | Trever Miller | 37 | L | 0 | 1 | 4.00 | 57 | 0 | 0 | 0 | 57 | 3 | 0 | 36.0 | 30 | 17 | 16 | 2 | 16 | 22 | 4 | 0 | 2 | 1.28 | 7.50 | 0.50 | 4.00 | 5.50 | 4.25 | 1.38 | 1991- 1- 41-DET | premium | premium | premium | MLB | 1996-2011 | 1991-2011 | 2010 |
| 59 | Fernando Salas | 25 | R | 0 | 0 | 3.52 | 27 | 0 | 0 | 0 | 27 | 11 | 0 | 30.2 | 28 | 13 | 12 | 4 | 15 | 29 | 2 | 0 | 0 | 1.40 | 8.22 | 1.17 | 4.40 | 8.51 | 3.82 | 1.93 | 2007- UDFA -SLN | premium | premium | premium | MLB | 2010-2019 | 2007-2025 | 2010 |
| 40 | P.J. Walters | 25 | R | 2 | 0 | 6.00 | 7 | 3 | 0 | 0 | 4 | 3 | 0 | 30.0 | 32 | 20 | 20 | 5 | 10 | 22 | 0 | 0 | 0 | 1.40 | 9.60 | 1.50 | 3.00 | 6.60 | 6.00 | 2.20 | 2006- 11- 346-SLN | premium | premium | premium | MLB | 2009-2013 | 2004-2015 | 2010 |
| 29 | Chris Carpenter | 35 | R | 16 | 9 | 3.22 | 35 | 35 | 1 | 0 | 0 | 0 | 0 | 235.0 | 214 | 99 | 84 | 21 | 63 | 179 | 3 | 0 | 13 | 1.18 | 8.20 | 0.80 | 2.41 | 6.86 | 3.79 | 2.84 | 1993- 1- 15-TOR | premium | premium | premium | MLB | 1997-2012 | 1994-2013 | 2010 |
| 50 | Adam Wainwright | 28 | R | 20 | 11 | 2.42 | 33 | 33 | 5 | 2 | 0 | 0 | 0 | 230.1 | 186 | 68 | 62 | 15 | 56 | 213 | 2 | 0 | 4 | 1.05 | 7.27 | 0.59 | 2.19 | 8.32 | 2.66 | 3.80 | 2000- 1- 29-ATL | premium | premium | premium | MLB | 2005-2023 | 2000-2023 | 2010 |
| 35 | Adam Ottavino | 24 | R | 0 | 2 | 8.46 | 5 | 3 | 0 | 0 | 2 | 0 | 0 | 22.1 | 37 | 21 | 21 | 5 | 9 | 12 | 1 | 0 | 0 | 2.06 | 14.91 | 2.01 | 3.63 | 4.84 | 8.46 | 1.33 | 2006- 1- 30-SLN | premium | premium | premium | MLB | 2010-2025 | 2004-2025 | 2010 |
| 22 | Joe Mather | 27 | R | 0 | 1 | 9.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 2.0 | 2 | 2 | 2 | 0 | 3 | 0 | 0 | 0 | 1 | 2.50 | 9.00 | 0.00 | 13.50 | 0.00 | 9.00 | 0.00 | 2001- 3- 104-SLN | premium | premium | premium | MLB | 2008-2012 | 2001-2014 | 2010 |
| 12 | Aaron Miles | 33 | R | 0 | 0 | 0.00 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 2.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 | 9.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1995- 19- 529-HOU | premium | premium | premium | MLB | 2003-2011 | 1995-2016 | 2010 |
| 48 | Mike MacDougal | 33 | R | 1 | 1 | 7.23 | 17 | 0 | 0 | 0 | 17 | 7 | 0 | 18.2 | 23 | 15 | 15 | 1 | 12 | 14 | 1 | 0 | 1 | 1.87 | 11.09 | 0.48 | 5.79 | 6.75 | 7.23 | 1.17 | 1999- 1- 25-KCA | premium | premium | premium | MLB | 2001-2012 | 1997-2014 | 2010 |
| 54 | Jaime Garcia | 23 | L | 13 | 8 | 2.70 | 28 | 28 | 1 | 1 | 0 | 0 | 0 | 163.1 | 151 | 64 | 49 | 9 | 64 | 132 | 4 | 1 | 3 | 1.32 | 8.32 | 0.50 | 3.53 | 7.27 | 3.53 | 2.06 | 2005- 22- 680-SLN | premium | premium | premium | MLB | 2008-2018 | 2006-2018 | 2010 |
| 3 | Felipe Lopez | 30 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.00 | 9.00 | 0.00 | 9.00 | 0.00 | 0.00 | 0.00 | 1998- 1- 8-TOR | premium | premium | premium | MLB | 2001-2011 | 1998-2011 | 2010 |
| 62 | Evan MacLane | 27 | L | 0 | 1 | 9.00 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 1.0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 2.00 | 9.00 | 9.00 | 9.00 | 0.00 | 9.00 | 0.00 | 2003- 25- 739-NYN | premium | premium | premium | MLB | 2010-2010 | 2003-2018 | 2010 |
| Totals: | 86 | 76 | 3.57 | 617 | 162 | 7 | 3 | 155 | 455 | 32 | 1453.2 | 1412 | 641 | 577 | 133 | 477 | 1094 | 42 | 4 | 48 | 1.30 | 8.74 | 0.82 | 2.95 | 6.77 | 3.97 | 2.29 | premium | premium | premium |