| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 9 | Hunter Pence | 27 | RF | R | 107 | 156 | 614 | 93 | 173 | 29 | 3 | 25 | 91 | 18 | 9 | 41 | 105 | 0 | 0 | 3 | 2 | 11 | 283 | 658 | 57 | 116 | .282 | .325 | .461 | .786 | .261 | .179 | .304 | 6.23 | 15.96 | 2.56 | 24.56 | 2004- 2- 64-HOU | premium | premium | premium | MLB | 2007-2020 | 2003-2020 | 2010 |
| 45 | Carlos Lee | 34 | LF | R | 96 | 157 | 605 | 67 | 149 | 29 | 1 | 24 | 89 | 3 | 3 | 37 | 59 | 3 | 0 | 4 | 1 | 20 | 252 | 649 | 54 | 95 | .246 | .291 | .417 | .708 | .231 | .171 | .238 | 5.70 | 9.09 | 1.59 | 25.21 | 1994- UDFA -CHA | premium | premium | premium | MLB | 1999-2012 | 1994-2012 | 2010 |
| 21 | Michael Bourn | 27 | CF | L | 99 | 141 | 535 | 84 | 142 | 25 | 6 | 2 | 38 | 52 | 12 | 59 | 109 | 3 | 6 | 2 | 5 | 6 | 185 | 605 | 33 | 109 | .265 | .341 | .346 | .687 | .265 | .081 | .329 | 9.75 | 18.02 | 1.85 | 267.50 | 2003- 4- 115-PHI | premium | premium | premium | MLB | 2006-2016 | 2001-2017 | 2010 |
| 8 | Jeff Keppinger | 30 | 2B | R | 103 | 137 | 514 | 62 | 148 | 34 | 1 | 6 | 59 | 4 | 1 | 51 | 36 | 1 | 5 | 4 | 1 | 15 | 202 | 575 | 41 | 107 | .288 | .351 | .393 | .744 | .210 | .105 | .298 | 8.87 | 6.26 | 0.71 | 85.67 | 2001- 4- 114-PIT | premium | premium | premium | MLB | 2004-2013 | 1999-2014 | 2010 |
| 23 | Chris Johnson | 25 | 3B | R | 111 | 94 | 341 | 40 | 105 | 22 | 2 | 11 | 52 | 3 | 0 | 15 | 91 | 2 | 0 | 4 | 2 | 8 | 164 | 362 | 35 | 70 | .308 | .337 | .481 | .818 | .226 | .173 | .387 | 4.14 | 25.14 | 6.07 | 31.00 | 2006- 4- 129-HOU | premium | premium | premium | MLB | 2009-2016 | 2004-2017 | 2010 |
| 17 | Lance Berkman | 34 | 1B | B | 108 | 85 | 298 | 39 | 73 | 16 | 1 | 13 | 49 | 3 | 2 | 60 | 70 | 0 | 0 | 0 | 4 | 12 | 130 | 358 | 30 | 43 | .245 | .372 | .436 | .808 | .396 | .191 | .279 | 16.76 | 19.55 | 1.17 | 22.92 | 1997- 1- 16-HOU | premium | premium | premium | MLB | 1999-2013 | 1995-2013 | 2010 |
| 77 | Pedro Feliz | 35 | 3B | R | 73 | 97 | 289 | 22 | 64 | 12 | 1 | 4 | 31 | 1 | 1 | 9 | 31 | 1 | 0 | 5 | 1 | 9 | 90 | 304 | 17 | 47 | .221 | .243 | .311 | .554 | .121 | .090 | .232 | 2.96 | 10.20 | 3.44 | 72.25 | 1994- UDFA -SFN | premium | premium | premium | MLB | 2000-2010 | 1998-2012 | 2010 |
| 55 | Humberto Quintero | 30 | C | R | 79 | 88 | 265 | 13 | 62 | 10 | 0 | 4 | 20 | 0 | 0 | 8 | 59 | 2 | 1 | 0 | 2 | 5 | 84 | 276 | 14 | 48 | .234 | .262 | .317 | .579 | .113 | .083 | .287 | 2.90 | 21.38 | 7.38 | 66.25 | 1997- UDFA -CHA | premium | premium | premium | MLB | 2003-2014 | 1999-2016 | 2010 |
| 12 | Tommy Manzella | 27 | SS | R | 74 | 83 | 258 | 17 | 58 | 7 | 0 | 1 | 21 | 0 | 1 | 13 | 71 | 3 | 5 | 3 | 1 | 6 | 68 | 282 | 8 | 50 | .225 | .267 | .264 | .531 | .085 | .039 | .302 | 4.61 | 25.18 | 5.46 | 258.00 | 2005- 3- 89-HOU | premium | premium | premium | MLB | 2009-2010 | 2002-2013 | 2010 |
| 36 | Angel Sanchez | 26 | SS | R | 91 | 65 | 250 | 30 | 70 | 9 | 4 | 0 | 25 | 0 | 1 | 11 | 45 | 2 | 6 | 0 | 0 | 8 | 87 | 269 | 13 | 57 | .280 | .316 | .348 | .664 | .108 | .068 | .341 | 4.09 | 16.73 | 4.09 | 0.00 | 2001- 11- 325-KCA | premium | premium | premium | MLB | 2006-2013 | 2001-2016 | 2010 |
| 27 | Geoff Blum | 37 | SS-3B | B | 93 | 93 | 202 | 22 | 54 | 10 | 1 | 2 | 22 | 0 | 0 | 15 | 33 | 1 | 0 | 0 | 2 | 3 | 72 | 218 | 13 | 41 | .267 | .321 | .356 | .677 | .163 | .089 | .311 | 6.88 | 15.14 | 2.20 | 101.00 | 1994- 7- 196-MON | premium | premium | premium | MLB | 1999-2012 | 1992-2012 | 2010 |
| 15 | Jason Castro | 23 | C | L | 81 | 67 | 195 | 26 | 40 | 8 | 1 | 2 | 8 | 0 | 0 | 22 | 41 | 0 | 0 | 0 | 2 | 4 | 56 | 217 | 11 | 29 | .205 | .286 | .287 | .573 | .195 | .082 | .250 | 10.14 | 18.89 | 1.86 | 97.50 | 2008- 1- 10-HOU | premium | premium | premium | MLB | 2010-2022 | 2006-2022 | 2010 |
| 4 | Jason Michaels | 34 | LF | R | 105* | 106 | 186 | 23 | 47 | 14 | 1 | 8 | 26 | 0 | 0 | 12 | 29 | 4 | 0 | 1 | 1 | 3 | 87 | 203 | 23 | 24 | .253 | .310 | .468 | .778 | .280 | .215 | .260 | 5.91 | 14.29 | 2.42 | 23.25 | 1998- 4- 104-PHI | premium | premium | premium | MLB | 2001-2011 | 1997-2012 | 2010 |
| 29 | Brett Wallace | 23 | 1B | L | 85* | 51 | 144 | 14 | 32 | 6 | 1 | 2 | 13 | 0 | 0 | 8 | 50 | 7 | 0 | 0 | 3 | 3 | 46 | 159 | 9 | 23 | .222 | .296 | .319 | .615 | .153 | .097 | .326 | 5.03 | 31.45 | 6.25 | 72.00 | 2008- 1- 13-SLN | premium | premium | premium | MLB | 2010-2016 | 2006-2016 | 2010 |
| 11 | Jason Bourgeois | 28 | LF-CF | R | 83* | 69 | 123 | 16 | 27 | 4 | 1 | 0 | 3 | 12 | 4 | 13 | 16 | 0 | 0 | 0 | 0 | 5 | 33 | 136 | 5 | 22 | .220 | .294 | .268 | .562 | .220 | .048 | .252 | 9.56 | 11.76 | 1.23 | 0.00 | 2000- 2- 56-TEX | premium | premium | premium | MLB | 2008-2015 | 2000-2018 | 2010 |
| 3 | Kazuo Matsui | 34 | 2B | B | 27 | 71 | 4 | 10 | 1 | 0 | 0 | 1 | 1 | 1 | 4 | 10 | 1 | 2 | 0 | 0 | 0 | 11 | 78 | 1 | 9 | .141 | .197 | .155 | .352 | .070 | .014 | .164 | 5.13 | 12.82 | 2.50 | 0.00 | 2003- UDFA -NYN | premium | premium | premium | MLB | 2004-2010 | 1995-2018 | 2010 | |
| 18 | Cory Sullivan | 30 | LF | L | 57 | 64 | 6 | 12 | 1 | 1 | 0 | 4 | 0 | 0 | 6 | 18 | 0 | 1 | 0 | 0 | 2 | 15 | 71 | 2 | 10 | .188 | .257 | .234 | .491 | .141 | .046 | .261 | 8.45 | 25.35 | 3.00 | 0.00 | 2001- 7- 214-COL | premium | premium | premium | MLB | 2005-2010 | 2000-2012 | 2010 | |
| 51 | Wandy Rodriguez | 31 | P | B | 33 | 63 | 4 | 12 | 2 | 0 | 0 | 4 | 0 | 0 | 1 | 23 | 0 | 9 | 1 | 0 | 0 | 14 | 74 | 2 | 10 | .190 | .200 | .222 | .422 | .048 | .032 | .293 | 1.35 | 31.08 | 23.00 | 0.00 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2005-2015 | 2001-2015 | 2010 | |
| 39 | Brett Myers | 29 | P | R | 31 | 62 | 2 | 11 | 1 | 0 | 0 | 2 | 0 | 0 | 2 | 25 | 0 | 11 | 1 | 0 | 0 | 12 | 76 | 1 | 10 | .177 | .200 | .194 | .394 | .048 | .017 | .289 | 2.63 | 32.89 | 12.50 | 0.00 | 1999- 1- 12-PHI | premium | premium | premium | MLB | 2002-2013 | 1999-2013 | 2010 | |
| 36 | Kevin Cash | 32 | C | R | 70* | 20 | 54 | 3 | 11 | 1 | 0 | 2 | 4 | 0 | 0 | 5 | 13 | 0 | 2 | 0 | 0 | 2 | 18 | 61 | 3 | 8 | .204 | .271 | .333 | .604 | .222 | .129 | .231 | 8.20 | 21.31 | 2.60 | 27.00 | 1999- UDFA -TOR | premium | premium | premium | MLB | 2002-2010 | 1997-2011 | 2010 |
| 18 | Anderson Hernandez | 27 | 2B | B | 81* | 32 | 48 | 7 | 9 | 2 | 0 | 0 | 1 | 2 | 0 | 8 | 10 | 0 | 0 | 0 | 0 | 1 | 11 | 56 | 2 | 7 | .188 | .304 | .229 | .533 | .250 | .041 | .237 | 14.29 | 17.86 | 1.25 | 0.00 | 2001- UDFA -DET | premium | premium | premium | MLB | 2005-2010 | 2001-2018 | 2010 |
| 46 | J.R. Towles | 26 | C | R | 17 | 47 | 3 | 9 | 3 | 0 | 1 | 8 | 0 | 0 | 2 | 12 | 1 | 0 | 1 | 0 | 2 | 15 | 51 | 4 | 5 | .191 | .235 | .319 | .554 | .170 | .128 | .229 | 3.92 | 23.53 | 6.00 | 47.00 | 2004- 20- 604-HOU | premium | premium | premium | MLB | 2007-2011 | 2004-2014 | 2010 | |
| 20 | Bud Norris | 25 | P | R | 27 | 44 | 2 | 7 | 2 | 0 | 0 | 2 | 0 | 0 | 2 | 13 | 0 | 10 | 0 | 0 | 1 | 9 | 56 | 2 | 5 | .159 | .196 | .205 | .401 | .091 | .046 | .226 | 3.57 | 23.21 | 6.50 | 0.00 | 2006- 6- 189-HOU | premium | premium | premium | MLB | 2009-2018 | 2004-2021 | 2010 | |
| 19 | Brian Bogusevic | 26 | LF | L | 19 | 28 | 5 | 5 | 3 | 0 | 0 | 3 | 1 | 1 | 3 | 12 | 0 | 0 | 0 | 0 | 2 | 8 | 31 | 3 | 2 | .179 | .258 | .286 | .544 | .214 | .107 | .313 | 9.68 | 38.71 | 4.00 | 0.00 | 2005- 1- 24-HOU | premium | premium | premium | MLB | 2010-2015 | 2003-2017 | 2010 | |
| 44 | Roy Oswalt | 32 | P | R | 18 | 28 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 11 | 0 | 7 | 0 | 0 | 1 | 4 | 36 | 0 | 4 | .143 | .172 | .143 | .315 | .036 | .000 | .235 | 2.78 | 30.56 | 11.00 | 0.00 | 1996- 23- 684-HOU | premium | premium | premium | MLB | 2001-2013 | 1997-2013 | 2010 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 52 | Felipe Paulino | 26 | P | R | 18 | 24 | 1 | 7 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 8 | 1 | 3 | 0 | 0 | 1 | 8 | 29 | 1 | 6 | .292 | .346 | .333 | .679 | .083 | .041 | .438 | 3.45 | 27.59 | 8.00 | 0.00 | 2001- UDFA -HOU | premium | premium | premium | MLB | 2007-2014 | 2003-2019 | 2010 | |
| 30 | J.A. Happ | 27 | P | L | 13 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | 24 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 29.17 | 0.00 | 0.00 | 2004- 3- 92-PHI | premium | premium | premium | MLB | 2007-2021 | 2002-2021 | 2010 | |
| 26 | Oswaldo Navarro | 25 | SS | R | 14 | 20 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 25 | 0 | 1 | .050 | .240 | .050 | .290 | .250 | .000 | .063 | 20.00 | 16.00 | 0.80 | 0.00 | 2001- UDFA -SEA | premium | premium | premium | MLB | 2006-2010 | 2003-2012 | 2010 | |
| 16 | Matt Downs | 26 | SS-3B | R | 86* | 11 | 19 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 2 | 21 | 0 | 2 | .105 | .190 | .105 | .295 | .053 | .000 | .118 | 4.76 | 9.52 | 2.00 | 0.00 | 2006- 36-1076-SFN | premium | premium | premium | MLB | 2009-2012 | 2004-2013 | 2010 |
| 28 | Nelson Figueroa | 36 | P | R | 18 | 13 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5 | 0 | 0 | 0 | 2 | 18 | 0 | 2 | .154 | .154 | .154 | .308 | .000 | .000 | .182 | 0.00 | 11.11 | 0.00 | 0.00 | 1995- 30- 833-NYN | premium | premium | premium | MLB | 2000-2011 | 1995-2022 | 2010 | |
| 38 | Brian Moehler | 38 | P | R | 18 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 10 | 0 | 1 | .100 | .100 | .100 | .200 | .000 | .000 | .143 | 0.00 | 30.00 | 0.00 | 0.00 | 1993- 6- 165-DET | premium | premium | premium | MLB | 1996-2010 | 1993-2010 | 2010 | |
| 53 | Wesley Wright | 25 | P | R | 11 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 37.50 | 0.00 | 0.00 | 2003- 7- 211-LAN | premium | premium | premium | MLB | 2008-2015 | 2003-2017 | 2010 | |
| 41 | Brian Esposito | 31 | C | R | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 2000- 5- 152-BOS | premium | premium | premium | MLB | 2010-2010 | 1998-2012 | 2010 | |
| 48 | Tim Byrdak | 36 | P | L | 59 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 1994- 5- 135-KCA | premium | premium | premium | MLB | 1998-2013 | 1994-2013 | 2010 | |
| 47 | Jeff Fulchino | 30 | P | R | 46 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2001- 8- 242-MIA | premium | premium | premium | MLB | 2006-2011 | 2001-2013 | 2010 | |
| 73 | Gustavo Chacin | 29 | P | L | 40 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 0 | 1.000 | 1.000 | 4.000 | 5.000 | 3.000 | 3.000 | .000 | 0.00 | 0.00 | 0.00 | 1.00 | 1998- UDFA -TOR | premium | premium | premium | MLB | 2004-2010 | 1999-2013 | 2010 | |
| 58 | Fernando Abad | 24 | P | L | 22 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2002- UDFA -HOU | premium | premium | premium | MLB | 2010-2023 | 2007-2025 | 2010 | |
| Totals: | 2042 | 5452 | 611 | 1348 | 252 | 25 | 108 | 577 | 100 | 36 | 415 | 1025 | 33 | 75 | 29 | 27 | 130 | 1974 | 6004 | 385 | 963 | .247 | .303 | .362 | .665 | .203 | .115 | .285 | 6.91 | 17.07 | 2.47 | 50.48 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 52 | Felipe Paulino | 26 | R | 1 | 9 | 5.11 | 19 | 14 | 0 | 0 | 5 | 0 | 0 | 91.2 | 95 | 63 | 52 | 4 | 46 | 83 | 6 | 1 | 3 | 1.54 | 9.33 | 0.39 | 4.52 | 8.15 | 6.19 | 1.80 | 2001- UDFA -HOU | premium | premium | premium | MLB | 2007-2014 | 2003-2019 | 2010 |
| 37 | Brandon Lyon | 30 | R | 6 | 6 | 3.12 | 79 | 0 | 0 | 0 | 79 | 28 | 20 | 78.0 | 68 | 28 | 27 | 2 | 31 | 54 | 3 | 0 | 3 | 1.27 | 7.85 | 0.23 | 3.58 | 6.23 | 3.23 | 1.74 | 1999- 14- 433-TOR | premium | premium | premium | MLB | 2001-2013 | 2000-2014 | 2010 |
| 30 | J.A. Happ | 27 | L | 5 | 4 | 3.75 | 13 | 13 | 1 | 1 | 0 | 0 | 0 | 72.0 | 60 | 33 | 30 | 7 | 35 | 61 | 3 | 0 | 1 | 1.32 | 7.50 | 0.88 | 4.38 | 7.63 | 4.13 | 1.74 | 2004- 3- 92-PHI | premium | premium | premium | MLB | 2007-2021 | 2002-2021 | 2010 |
| 59 | Wilton Lopez | 26 | R | 5 | 2 | 2.96 | 68 | 0 | 0 | 0 | 68 | 14 | 1 | 67.0 | 66 | 23 | 22 | 4 | 5 | 50 | 2 | 2 | 0 | 1.06 | 8.87 | 0.54 | 0.67 | 6.72 | 3.09 | 10.00 | 2002- UDFA -NYA | premium | premium | premium | MLB | 2009-2014 | 2004-2015 | 2010 |
| 28 | Nelson Figueroa | 36 | R | 5 | 3 | 3.22 | 18 | 10 | 0 | 0 | 8 | 1 | 0 | 67.0 | 64 | 28 | 24 | 9 | 25 | 58 | 4 | 0 | 2 | 1.33 | 8.60 | 1.21 | 3.36 | 7.79 | 3.76 | 2.32 | 1995- 30- 833-NYN | premium | premium | premium | MLB | 2000-2011 | 1995-2022 | 2010 |
| 56 | Henry Villar | 23 | R | 0 | 0 | 4.50 | 8 | 0 | 0 | 0 | 8 | 3 | 0 | 6.0 | 5 | 3 | 3 | 0 | 3 | 3 | 0 | 1 | 1 | 1.33 | 7.50 | 0.00 | 4.50 | 4.50 | 4.50 | 1.00 | 2005- UDFA -HOU | premium | premium | premium | MLB | 2010-2010 | 2008-2014 | 2010 |
| 38 | Brian Moehler | 38 | R | 1 | 4 | 4.92 | 20 | 8 | 0 | 0 | 12 | 5 | 0 | 56.2 | 66 | 32 | 31 | 5 | 26 | 28 | 0 | 1 | 1 | 1.62 | 10.48 | 0.79 | 4.13 | 4.45 | 5.08 | 1.08 | 1993- 6- 165-DET | premium | premium | premium | MLB | 1996-2010 | 1993-2010 | 2010 |
| 22 | Matt Lindstrom | 30 | R | 2 | 5 | 4.39 | 58 | 0 | 0 | 0 | 58 | 41 | 23 | 53.1 | 68 | 26 | 26 | 5 | 20 | 43 | 8 | 0 | 0 | 1.65 | 11.48 | 0.84 | 3.38 | 7.26 | 4.39 | 2.15 | 2002- 10- 297-NYN | premium | premium | premium | MLB | 2007-2014 | 2002-2015 | 2010 |
| 47 | Jeff Fulchino | 30 | R | 2 | 1 | 5.51 | 50 | 0 | 0 | 0 | 50 | 16 | 0 | 47.1 | 53 | 30 | 29 | 7 | 22 | 46 | 2 | 0 | 3 | 1.58 | 10.08 | 1.33 | 4.18 | 8.75 | 5.70 | 2.09 | 2001- 8- 242-MIA | premium | premium | premium | MLB | 2006-2011 | 2001-2013 | 2010 |
| 60 | Josh Banks | 27 | R | 0 | 1 | 13.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 4.0 | 8 | 6 | 6 | 1 | 4 | 1 | 0 | 0 | 0 | 3.00 | 18.00 | 2.25 | 9.00 | 2.25 | 13.50 | 0.25 | 2003- 2- 50-TOR | premium | premium | premium | MLB | 2007-2010 | 2001-2011 | 2010 |
| 48 | Tim Byrdak | 36 | L | 2 | 2 | 3.49 | 64 | 0 | 0 | 0 | 64 | 9 | 0 | 38.2 | 40 | 15 | 15 | 4 | 20 | 29 | 2 | 0 | 0 | 1.55 | 9.31 | 0.93 | 4.66 | 6.75 | 3.49 | 1.45 | 1994- 5- 135-KCA | premium | premium | premium | MLB | 1998-2013 | 1994-2013 | 2010 |
| 73 | Gustavo Chacin | 29 | L | 2 | 2 | 4.70 | 44 | 0 | 0 | 0 | 44 | 12 | 1 | 38.1 | 51 | 22 | 20 | 3 | 20 | 31 | 2 | 0 | 0 | 1.85 | 11.97 | 0.70 | 4.70 | 7.28 | 5.17 | 1.55 | 1998- UDFA -TOR | premium | premium | premium | MLB | 2004-2010 | 1999-2013 | 2010 |
| 53 | Wesley Wright | 25 | L | 1 | 2 | 5.73 | 14 | 4 | 0 | 0 | 10 | 3 | 0 | 33.0 | 37 | 27 | 21 | 6 | 13 | 29 | 0 | 0 | 3 | 1.52 | 10.09 | 1.64 | 3.55 | 7.91 | 7.36 | 2.23 | 2003- 7- 211-LAN | premium | premium | premium | MLB | 2008-2015 | 2003-2017 | 2010 |
| 43 | Chris Sampson | 32 | R | 1 | 0 | 5.93 | 35 | 0 | 0 | 0 | 35 | 9 | 0 | 30.1 | 43 | 22 | 20 | 7 | 8 | 16 | 1 | 0 | 1 | 1.68 | 12.76 | 2.08 | 2.37 | 4.75 | 6.53 | 2.00 | 1999- 8- 263-HOU | premium | premium | premium | MLB | 2006-2010 | 1999-2011 | 2010 |
| 63 | Sammy Gervacio | 25 | R | 0 | 1 | 12.27 | 6 | 0 | 0 | 0 | 6 | 1 | 0 | 3.2 | 4 | 6 | 5 | 1 | 5 | 3 | 1 | 1 | 0 | 2.45 | 9.82 | 2.45 | 12.27 | 7.36 | 14.73 | 0.60 | 2002- UDFA -HOU | premium | premium | premium | MLB | 2009-2010 | 2005-2019 | 2010 |
| 39 | Brett Myers | 29 | R | 14 | 8 | 3.14 | 33 | 33 | 2 | 0 | 0 | 0 | 0 | 223.2 | 212 | 88 | 78 | 20 | 66 | 180 | 2 | 0 | 3 | 1.24 | 8.53 | 0.80 | 2.66 | 7.24 | 3.54 | 2.73 | 1999- 1- 12-PHI | premium | premium | premium | MLB | 2002-2013 | 1999-2013 | 2010 |
| 56 | Gary Majewski | 30 | R | 0 | 0 | 22.50 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 2.0 | 5 | 5 | 5 | 1 | 1 | 1 | 0 | 0 | 0 | 3.00 | 22.50 | 4.50 | 4.50 | 4.50 | 22.50 | 1.00 | 1998- 2- 59-CHA | premium | premium | premium | MLB | 2004-2010 | 1999-2015 | 2010 |
| 51 | Wandy Rodriguez | 31 | L | 11 | 12 | 3.60 | 32 | 32 | 0 | 0 | 0 | 0 | 0 | 195.0 | 183 | 95 | 78 | 16 | 68 | 178 | 8 | 0 | 9 | 1.29 | 8.45 | 0.74 | 3.14 | 8.22 | 4.38 | 2.62 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2005-2015 | 2001-2015 | 2010 |
| 58 | Fernando Abad | 24 | L | 0 | 1 | 2.84 | 22 | 0 | 0 | 0 | 22 | 6 | 0 | 19.0 | 14 | 6 | 6 | 3 | 5 | 12 | 0 | 0 | 0 | 1.00 | 6.63 | 1.42 | 2.37 | 5.68 | 2.84 | 2.40 | 2002- UDFA -HOU | premium | premium | premium | MLB | 2010-2023 | 2007-2025 | 2010 |
| 54 | Mark Melancon | 25 | R | 2 | 0 | 3.12 | 20 | 0 | 0 | 0 | 20 | 2 | 0 | 17.1 | 12 | 8 | 6 | 1 | 8 | 19 | 2 | 0 | 1 | 1.15 | 6.23 | 0.52 | 4.15 | 9.87 | 4.15 | 2.38 | 2006- 9- 284-NYA | premium | premium | premium | MLB | 2009-2022 | 2004-2023 | 2010 |
| 20 | Bud Norris | 25 | R | 9 | 10 | 4.92 | 27 | 27 | 0 | 0 | 0 | 0 | 0 | 153.2 | 151 | 94 | 84 | 18 | 77 | 158 | 5 | 2 | 6 | 1.48 | 8.84 | 1.05 | 4.51 | 9.25 | 5.51 | 2.05 | 2006- 6- 189-HOU | premium | premium | premium | MLB | 2009-2018 | 2004-2021 | 2010 |
| 44 | Roy Oswalt | 32 | R | 6 | 12 | 3.42 | 20 | 20 | 1 | 1 | 0 | 0 | 0 | 129.0 | 109 | 52 | 49 | 13 | 34 | 120 | 2 | 1 | 2 | 1.11 | 7.60 | 0.91 | 2.37 | 8.37 | 3.63 | 3.53 | 1996- 23- 684-HOU | premium | premium | premium | MLB | 2001-2013 | 1997-2013 | 2010 |
| 41 | Casey Daigle | 29 | R | 1 | 1 | 11.32 | 13 | 0 | 0 | 0 | 13 | 4 | 0 | 10.1 | 25 | 13 | 13 | 3 | 6 | 6 | 4 | 0 | 0 | 3.00 | 21.77 | 2.61 | 5.23 | 5.23 | 11.32 | 1.00 | 1999- 1- 31-ARI | premium | premium | premium | MLB | 2004-2010 | 2000-2011 | 2010 |
| 66 | Enerio Del Rosario | 24 | R | 0 | 0 | 20.25 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 1.1 | 4 | 3 | 3 | 0 | 0 | 1 | 0 | 0 | 1 | 3.00 | 27.00 | 0.00 | 0.00 | 6.75 | 20.25 | 0.00 | 2005- UDFA -CIN | premium | premium | premium | MLB | 2010-2012 | 2007-2013 | 2010 |
| 36 | Kevin Cash | 32 | R | 0 | 0 | 9.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 | 27.00 | 0.00 | 0.00 | 0.00 | 9.00 | 0.00 | 1999- UDFA -TOR | premium | premium | premium | MLB | 2002-2010 | 1997-2011 | 2010 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| Totals: | 76 | 86 | 4.09 | 669 | 162 | 4 | 2 | 158 | 507 | 45 | 1439.1 | 1446 | 729 | 654 | 140 | 548 | 1210 | 57 | 9 | 40 | 1.39 | 9.04 | 0.88 | 3.43 | 7.57 | 4.56 | 2.21 | premium | premium | premium |