| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 12 | Jon Gaston | 23 | RF | L | 100 | 132 | 461 | 64 | 113 | 16 | 8 | 13 | 51 | 13 | 5 | 47 | 105 | 6 | 2 | 4 | 1 | 2 | 184 | 520 | 37 | 76 | .245 | .320 | .399 | .719 | .273 | .154 | .288 | 9.04 | 20.19 | 2.23 | 35.46 | 2008- 7- 212-HOU | premium | premium | premium | AA | 2006-2015 | 2010 | |
| 21 | Koby Clemens | 23 | 1B | R | 113 | 127 | 452 | 75 | 109 | 22 | 3 | 26 | 85 | 9 | 3 | 69 | 143 | 9 | 0 | 5 | 3 | 8 | 215 | 535 | 51 | 58 | .241 | .350 | .476 | .826 | .400 | .235 | .288 | 12.90 | 26.73 | 2.07 | 17.38 | 2005- 8- 254-HOU | premium | premium | premium | AAA | 2005-2014 | 2010 | |
| 7 | JB Shuck | 23 | LF-CF | L | 102 | 101 | 389 | 52 | 116 | 14 | 2 | 2 | 28 | 9 | 9 | 46 | 56 | 0 | 0 | 0 | 1 | 2 | 140 | 435 | 18 | 98 | .298 | .372 | .360 | .732 | .180 | .062 | .344 | 10.57 | 12.87 | 1.22 | 194.50 | 2008- 6- 182-HOU | premium | premium | premium | MLB | 2011-2019 | 2006-2019 | 2010 |
| 5 | Jhon Florentino | 26 | 3B | R | 94 | 95 | 316 | 30 | 81 | 17 | 3 | 4 | 36 | 2 | 2 | 27 | 55 | 0 | 4 | 1 | 1 | 13 | 116 | 348 | 24 | 57 | .256 | .314 | .367 | .681 | .196 | .111 | .298 | 7.76 | 15.80 | 2.04 | 79.00 | premium | premium | premium | AA | 2005-2010 | 2010 | ||
| 6 | Jimmy Van Ostrand | 25 | 1B | R | 84 | 105 | 312 | 22 | 76 | 17 | 0 | 3 | 44 | 1 | 3 | 18 | 62 | 1 | 1 | 3 | 0 | 14 | 102 | 335 | 20 | 56 | .244 | .284 | .327 | .611 | .135 | .083 | .292 | 5.37 | 18.51 | 3.44 | 104.00 | 2006- 8- 249-HOU | premium | premium | premium | AAA | 2005-2013 | 2010 | |
| 25 | David Cook | 28 | LF | R | 104 | 109 | 310 | 50 | 76 | 13 | 2 | 11 | 36 | 7 | 2 | 40 | 84 | 4 | 1 | 2 | 0 | 5 | 126 | 357 | 26 | 50 | .245 | .337 | .406 | .743 | .306 | .161 | .300 | 11.20 | 23.53 | 2.10 | 28.18 | 2003- 9- 262-CHA | premium | premium | premium | AAA | 2000-2011 | 2010 | |
| 7 | Wladimir Sutil | 25 | SS | R | 90 | 74 | 264 | 29 | 73 | 7 | 0 | 0 | 17 | 15 | 4 | 19 | 23 | 1 | 5 | 3 | 1 | 9 | 80 | 292 | 7 | 66 | .277 | .324 | .303 | .627 | .140 | .026 | .299 | 6.51 | 7.88 | 1.21 | 0.00 | 2003- UDFA -HOU | premium | premium | premium | AAA | 2004-2013 | 2010 | |
| 8 | Lou Santangelo | 27 | C | R | 95 | 84 | 252 | 22 | 59 | 11 | 0 | 6 | 20 | 0 | 1 | 35 | 64 | 0 | 4 | 0 | 1 | 8 | 88 | 291 | 17 | 42 | .234 | .328 | .349 | .677 | .250 | .115 | .291 | 12.03 | 21.99 | 1.83 | 42.00 | 2004- 4- 124-HOU | premium | premium | premium | AAA | 2002-2012 | 2010 | |
| 28 | T.J. Steele | 23 | CF | R | 80 | 67 | 241 | 25 | 55 | 9 | 3 | 2 | 18 | 9 | 4 | 10 | 67 | 0 | 1 | 0 | 0 | 3 | 76 | 252 | 14 | 41 | .228 | .259 | .315 | .574 | .149 | .087 | .308 | 3.97 | 26.59 | 6.70 | 120.50 | 2008- 4- 122-HOU | premium | premium | premium | AA | 2006-2012 | 2010 | |
| 4 | German Duran | 25 | 2B | R | 99 | 64 | 222 | 24 | 63 | 10 | 0 | 4 | 28 | 1 | 2 | 20 | 29 | 0 | 0 | 5 | 0 | 3 | 85 | 247 | 14 | 49 | .284 | .336 | .383 | .719 | .185 | .099 | .304 | 8.10 | 11.74 | 1.45 | 55.50 | 2005- 6- 189-TEX | premium | premium | premium | MLB | 2008-2008 | 2004-2014 | 2010 |
| 18 | Michael Affronti | 26 | SS-3B | R | 93 | 62 | 219 | 22 | 61 | 5 | 3 | 3 | 29 | 5 | 5 | 13 | 40 | 2 | 1 | 2 | 0 | 4 | 81 | 237 | 11 | 50 | .279 | .322 | .370 | .692 | .151 | .091 | .326 | 5.49 | 16.88 | 3.08 | 73.00 | 2006- 17- 518-OAK | premium | premium | premium | AAA | 2003-2010 | 2010 | |
| 45 | J.D. Martinez | 22 | RF-LF | R | 106 | 50 | 189 | 24 | 57 | 9 | 1 | 3 | 25 | 2 | 2 | 15 | 42 | 2 | 0 | 1 | 0 | 9 | 77 | 207 | 13 | 44 | .302 | .357 | .407 | .764 | .185 | .105 | .372 | 7.25 | 20.29 | 2.80 | 63.00 | 2009- 20- 611-HOU | premium | premium | premium | MLB | 2011-2024 | 2009-2024 | 2010 |
| 3 | Marcos Cabral | 26 | SS | R | 95 | 52 | 185 | 19 | 49 | 8 | 0 | 4 | 20 | 2 | 3 | 15 | 22 | 0 | 1 | 0 | 0 | 3 | 69 | 201 | 12 | 37 | .265 | .320 | .373 | .693 | .184 | .108 | .283 | 7.46 | 10.95 | 1.47 | 46.25 | 2002- 31- 927-NYN | premium | premium | premium | AAA | 2003-2012 | 2010 | |
| 13 | Freddy Parejo | 25 | LF | R | 99 | 48 | 170 | 15 | 51 | 7 | 1 | 0 | 17 | 7 | 1 | 7 | 31 | 4 | 0 | 0 | 1 | 4 | 60 | 181 | 8 | 43 | .300 | .343 | .353 | .696 | .129 | .053 | .367 | 3.87 | 17.13 | 4.43 | 0.00 | premium | premium | premium | AAA | 2004-2011 | 2010 | ||
| 4 | Albert Cartwright | 22 | 2B | R | 80* | 35 | 140 | 15 | 32 | 4 | 1 | 0 | 7 | 7 | 4 | 11 | 39 | 1 | 2 | 0 | 0 | 5 | 38 | 154 | 5 | 27 | .229 | .289 | .271 | .560 | .143 | .042 | .317 | 7.14 | 25.32 | 3.55 | 0.00 | 2007- 36-1096-HOU | premium | premium | premium | AA | 2007-2016 | 2010 | |
| 9 | Jose Vallejo | 23 | 2B | B | 43* | 34 | 99 | 6 | 11 | 0 | 0 | 0 | 2 | 1 | 1 | 7 | 37 | 0 | 1 | 0 | 0 | 2 | 11 | 107 | 0 | 11 | .111 | .170 | .111 | .281 | .071 | .000 | .177 | 6.54 | 34.58 | 5.29 | 0.00 | premium | premium | premium | AAA | 2005-2011 | 2010 | ||
| 30 | Jonathon Fixler | 24 | C | R | 115* | 33 | 98 | 12 | 26 | 4 | 2 | 5 | 14 | 1 | 2 | 13 | 33 | 2 | 2 | 0 | 1 | 1 | 49 | 115 | 11 | 15 | .265 | .363 | .500 | .863 | .357 | .235 | .350 | 11.30 | 28.70 | 2.54 | 19.60 | 2007- 19- 591-HOU | premium | premium | premium | AAA | 2005-2011 | 2010 | |
| 32 | Kody Kirkland | 27 | 3B | R | 19 | 56 | 12 | 16 | 6 | 0 | 2 | 8 | 3 | 0 | 7 | 16 | 1 | 1 | 0 | 0 | 0 | 28 | 65 | 8 | 8 | .286 | .375 | .500 | .875 | .393 | .214 | .368 | 10.77 | 24.62 | 2.29 | 28.00 | 2001- 30- 894-PIT | premium | premium | premium | AAA | 2002-2013 | 2010 | ||
| 19 | Federico Hernandez | 22 | C | B | 19 | 56 | 8 | 17 | 5 | 0 | 1 | 5 | 0 | 0 | 4 | 11 | 0 | 0 | 0 | 0 | 1 | 25 | 60 | 6 | 11 | .304 | .350 | .446 | .796 | .214 | .142 | .364 | 6.67 | 18.33 | 2.75 | 56.00 | premium | premium | premium | AA | 2008-2011 | 2010 | |||
| 43 | Barry Butera | 23 | 2B | L | 22 | 51 | 3 | 9 | 0 | 1 | 0 | 1 | 0 | 0 | 2 | 11 | 0 | 1 | 0 | 0 | 6 | 11 | 54 | 1 | 8 | .176 | .208 | .216 | .424 | .078 | .040 | .225 | 3.70 | 20.37 | 5.50 | 0.00 | 2009- 21- 641-HOU | premium | premium | premium | AA | 2007-2010 | 2010 | ||
| 9 | Brian Esposito | 31 | C | R | 14 | 46 | 2 | 6 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 9 | 0 | 2 | 0 | 0 | 2 | 10 | 48 | 3 | 3 | .130 | .130 | .217 | .347 | .087 | .087 | .162 | 0.00 | 18.75 | 0.00 | 0.00 | 2000- 5- 152-BOS | premium | premium | premium | MLB | 2010-2010 | 1998-2012 | 2010 | |
| 51 | Michael Garciaparra | 27 | 2B-SS | R | 11 | 30 | 3 | 7 | 1 | 0 | 0 | 2 | 0 | 0 | 4 | 5 | 0 | 0 | 1 | 1 | 0 | 8 | 35 | 1 | 6 | .233 | .314 | .267 | .581 | .167 | .034 | .269 | 11.43 | 14.29 | 1.25 | 0.00 | 2001- 1- 36-SEA | premium | premium | premium | AAA | 2002-2010 | 2010 | ||
| - | Tommy Manzella | 27 | SS | R | 5 | 14 | 4 | 6 | 1 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 7 | 14 | 1 | 5 | .429 | .429 | .500 | .929 | -0.071 | .071 | .429 | 0.00 | 0.00 | 0.00 | 0.00 | 2005- 3- 89-HOU | premium | premium | premium | MLB | 2009-2010 | 2002-2013 | 2010 | |
| - | J.R. Towles | 26 | C | R | 5 | 14 | 3 | 2 | 1 | 0 | 0 | 3 | 2 | 0 | 4 | 4 | 2 | 0 | 0 | 0 | 0 | 3 | 20 | 1 | 1 | .143 | .400 | .214 | .614 | .500 | .071 | .200 | 20.00 | 20.00 | 1.00 | 0.00 | 2004- 20- 604-HOU | premium | premium | premium | MLB | 2007-2011 | 2004-2014 | 2010 | |
| 35 | Douglas Arguello | 25 | P | L | 8 | 13 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 7 | 0 | 4 | 0 | 0 | 0 | 2 | 19 | 0 | 2 | .154 | .267 | .154 | .421 | .154 | .000 | .333 | 10.53 | 36.84 | 3.50 | 0.00 | premium | premium | premium | AAA | 2003-2014 | 2010 | |||
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 55 | Ben Heath | 21 | C | R | 4 | 12 | 0 | 6 | 1 | 0 | 0 | 4 | 0 | 0 | 1 | 3 | 0 | 1 | 0 | 0 | 0 | 7 | 14 | 1 | 5 | .500 | .538 | .583 | 1.121 | .167 | .083 | .667 | 7.14 | 21.43 | 3.00 | 0.00 | 2010- 5- 153-HOU | premium | premium | premium | AA | 2008-2012 | 2010 | ||
| 29 | Tyler Lumsden | 27 | P | L | 10 | 12 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 8 | 1 | 3 | 0 | 0 | 0 | 2 | 16 | 0 | 2 | .167 | .231 | .167 | .398 | .000 | .000 | .500 | 0.00 | 50.00 | 0.00 | 0.00 | 2004- 1- 34-CHA | premium | premium | premium | AAA | 2002-2010 | 2010 | ||
| 23 | Jordan Lyles | 19 | P | R | 5 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 11 | 0 | 1 | .091 | .091 | .091 | .182 | .000 | .000 | .143 | 0.00 | 36.36 | 0.00 | 0.00 | 2008- 1- 38-HOU | premium | premium | premium | MLB | 2011-2024 | 2008-2024 | 2010 | |
| 44 | Jeremy Johnson | 27 | P | R | 9 | 9 | 3 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 3 | 0 | 1 | 0 | 0 | 0 | 3 | 12 | 0 | 3 | .333 | .455 | .333 | .788 | .222 | .000 | .500 | 16.67 | 25.00 | 1.50 | 0.00 | 2000- 11- 318-DET | premium | premium | premium | AAA | 2000-2010 | 2010 | ||
| - | Geoff Blum | 37 | SS | B | 3 | 9 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 10 | 2 | 0 | .222 | .300 | .444 | .744 | .333 | .222 | .222 | 10.00 | 0.00 | 0.00 | 0.00 | 1994- 7- 196-MON | premium | premium | premium | MLB | 1999-2012 | 1992-2012 | 2010 | |
| 26 | Dallas Keuchel | 22 | P | L | 5 | 8 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 6 | 0 | 1 | 0 | 0 | 0 | 2 | 9 | 1 | 0 | .125 | .125 | .250 | .375 | .125 | .125 | .500 | 0.00 | 66.67 | 0.00 | 0.00 | 2009- 7- 221-HOU | premium | premium | premium | MLB | 2012-2024 | 2007-2025 | 2010 | |
| 17 | Erick Abreu | 26 | P | R | 10 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 6 | 0 | 1 | .167 | .167 | .167 | .334 | .000 | .000 | .200 | 0.00 | 16.67 | 0.00 | 0.00 | 2002- UDFA -NYA | premium | premium | premium | AAA | 2003-2013 | 2010 | ||
| 31 | Henry Villar | 23 | P | R | 14 | 6 | 2 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3 | 0 | 0 | 1 | 4 | 10 | 1 | 2 | .500 | .571 | .667 | 1.238 | .333 | .167 | .500 | 10.00 | 0.00 | 0.00 | 0.00 | 2005- UDFA -HOU | premium | premium | premium | MLB | 2010-2010 | 2008-2014 | 2010 | |
| 20 | Jared Wells | 28 | P | R | 6 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 42.86 | 0.00 | 0.00 | 2002- 31- 925-SDN | premium | premium | premium | MLB | 2008-2008 | 2003-2017 | 2010 | |
| - | Jeff Keppinger | 30 | 2B | R | 2 | 5 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6 | 0 | 2 | .400 | .500 | .400 | .900 | .200 | .000 | .400 | 16.67 | 0.00 | 0.00 | 0.00 | 2001- 4- 114-PIT | premium | premium | premium | MLB | 2004-2013 | 1999-2014 | 2010 | |
| 25 | Sergio Perez | 25 | P | R | 2 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .250 | .250 | .250 | .500 | .000 | .000 | .500 | 0.00 | 50.00 | 0.00 | 0.00 | 2006- 2- 67-HOU | premium | premium | premium | AAA | 2004-2014 | 2010 | ||
| 43 | Bubbie Buzachero | 29 | P | R | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 25.00 | 0.00 | 0.00 | 2002- 23- 686-TOR | premium | premium | premium | AAA | 2000-2012 | 2010 | ||
| 16 | Chia-Jen Lo | 24 | P | R | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2008- UDFA -HOU | premium | premium | premium | MLB | 2013-2013 | 2009-2014 | 2010 | |
| 51 | Jailen Peguero | 29 | P | R | 11 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 2000- UDFA -HOU | premium | premium | premium | MLB | 2007-2008 | 2002-2021 | 2010 | |
| 25 | Polin Trinidad | 25 | P | L | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | premium | premium | premium | AAA | 2005-2011 | 2010 | |||
| - | John Curtis | 25 | C | L | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2007- 14- 449-CHA | premium | premium | premium | AAA | 2004-2010 | 2010 | ||
| 36 | Fernando Abad | 24 | P | L | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2002- UDFA -HOU | premium | premium | premium | MLB | 2010-2023 | 2007-2025 | 2010 | |
| 13 | Brian Wabick | 22 | P | R | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2007- 34-1038-HOU | premium | premium | premium | AA | 2007-2010 | 2010 | ||
| 38 | Matt Nevarez | 23 | P | R | 12 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2005- 10- 309-TEX | premium | premium | premium | AAA | 2005-2017 | 2010 | ||
| 26 | Edwin Walker | 26 | P | R | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2002- 9- 259-MIL | premium | premium | premium | AA | 2002-2013 | 2010 | ||
| Totals: | 1495 | 4700 | 548 | 1195 | 194 | 31 | 89 | 508 | 96 | 55 | 441 | 1030 | 36 | 46 | 27 | 11 | 107 | 1718 | 5250 | 314 | 881 | .254 | .321 | .366 | .687 | .214 | .111 | .307 | 8.40 | 19.62 | 2.34 | 52.81 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 29 | Tyler Lumsden | 27 | L | 4 | 8 | 4.04 | 20 | 16 | 1 | 0 | 4 | 1 | 0 | 91.1 | 92 | 47 | 41 | 4 | 34 | 33 | 7 | 1 | 2 | 1.38 | 9.07 | 0.39 | 3.35 | 3.25 | 4.63 | 0.97 | 2004- 1- 34-CHA | premium | premium | premium | AAA | 2002-2010 | 2010 | |
| 10 | T.J. Burton | 26 | R | 3 | 0 | 10.00 | 7 | 0 | 0 | 0 | 7 | 5 | 0 | 9.0 | 17 | 12 | 10 | 2 | 3 | 3 | 1 | 0 | 0 | 2.22 | 17.00 | 2.00 | 3.00 | 3.00 | 12.00 | 1.00 | 2001- 18- 547-CLE | premium | premium | premium | AAA | 2002-2010 | 2010 | |
| 17 | Erick Abreu | 26 | R | 4 | 5 | 3.34 | 31 | 9 | 0 | 0 | 22 | 14 | 0 | 86.1 | 80 | 35 | 32 | 11 | 21 | 77 | 1 | 0 | 3 | 1.17 | 8.34 | 1.15 | 2.19 | 8.03 | 3.65 | 3.67 | 2002- UDFA -NYA | premium | premium | premium | AAA | 2003-2013 | 2010 | |
| 20 | Jared Wells | 28 | R | 5 | 4 | 3.81 | 31 | 8 | 0 | 0 | 23 | 10 | 3 | 78.0 | 73 | 39 | 33 | 8 | 46 | 60 | 5 | 0 | 2 | 1.53 | 8.42 | 0.92 | 5.31 | 6.92 | 4.50 | 1.30 | 2002- 31- 925-SDN | premium | premium | premium | MLB | 2008-2008 | 2003-2017 | 2010 |
| 26 | Dallas Keuchel | 22 | L | 2 | 6 | 4.70 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 53.2 | 59 | 32 | 28 | 2 | 11 | 36 | 0 | 0 | 1 | 1.30 | 9.89 | 0.34 | 1.84 | 6.04 | 5.37 | 3.27 | 2009- 7- 221-HOU | premium | premium | premium | MLB | 2012-2024 | 2007-2025 | 2010 |
| 51 | Jailen Peguero | 29 | R | 3 | 4 | 1.70 | 32 | 0 | 0 | 0 | 32 | 13 | 3 | 53.0 | 38 | 11 | 10 | 1 | 22 | 56 | 8 | 2 | 3 | 1.13 | 6.45 | 0.17 | 3.74 | 9.51 | 1.87 | 2.55 | 2000- UDFA -HOU | premium | premium | premium | MLB | 2007-2008 | 2002-2021 | 2010 |
| 36 | Shane Wolf | 23 | L | 0 | 0 | 3.18 | 4 | 0 | 0 | 0 | 4 | 1 | 0 | 5.2 | 5 | 3 | 2 | 0 | 1 | 5 | 0 | 0 | 0 | 1.06 | 7.94 | 0.00 | 1.59 | 7.94 | 4.76 | 5.00 | 2008- 26- 782-HOU | premium | premium | premium | AA | 2005-2011 | 2010 | |
| 30 | Pat Urckfitz | 21 | L | 0 | 0 | 3.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 5.0 | 8 | 2 | 2 | 0 | 1 | 4 | 0 | 0 | 0 | 1.80 | 14.40 | 0.00 | 1.80 | 7.20 | 3.60 | 4.00 | 2008- UDFA -HOU | premium | premium | premium | AAA | 2008-2015 | 2010 | |
| 25 | Sergio Perez | 25 | R | 2 | 3 | 3.09 | 8 | 8 | 0 | 0 | 0 | 0 | 0 | 43.2 | 49 | 22 | 15 | 0 | 19 | 20 | 2 | 0 | 2 | 1.56 | 10.10 | 0.00 | 3.92 | 4.12 | 4.53 | 1.05 | 2006- 2- 67-HOU | premium | premium | premium | AAA | 2004-2014 | 2010 | |
| - | Felipe Paulino | 26 | R | 0 | 0 | 0.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 4.0 | 2 | 0 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 0.75 | 4.50 | 0.00 | 2.25 | 6.75 | 0.00 | 3.00 | 2001- UDFA -HOU | premium | premium | premium | MLB | 2007-2014 | 2003-2019 | 2010 |
| 36 | Fernando Abad | 24 | L | 4 | 3 | 2.50 | 14 | 4 | 0 | 0 | 10 | 0 | 0 | 39.2 | 48 | 16 | 11 | 3 | 6 | 33 | 2 | 1 | 0 | 1.36 | 10.89 | 0.68 | 1.36 | 7.49 | 3.63 | 5.50 | 2002- UDFA -HOU | premium | premium | premium | MLB | 2010-2023 | 2007-2025 | 2010 |
| 38 | Matt Nevarez | 23 | R | 2 | 1 | 3.76 | 36 | 0 | 0 | 0 | 36 | 9 | 1 | 38.1 | 30 | 17 | 16 | 1 | 46 | 41 | 2 | 0 | 0 | 1.98 | 7.04 | 0.23 | 10.80 | 9.63 | 3.99 | 0.89 | 2005- 10- 309-TEX | premium | premium | premium | AAA | 2005-2017 | 2010 | |
| 19 | Danny Meszaros | 24 | R | 3 | 1 | 3.09 | 26 | 0 | 0 | 0 | 26 | 23 | 10 | 32.0 | 28 | 13 | 11 | 1 | 16 | 42 | 2 | 1 | 1 | 1.38 | 7.88 | 0.28 | 4.50 | 11.81 | 3.66 | 2.63 | 2008- 48-1433-HOU | premium | premium | premium | AAA | 2005-2013 | 2010 | |
| 25 | Polin Trinidad | 25 | L | 1 | 3 | 4.02 | 5 | 4 | 0 | 0 | 1 | 1 | 0 | 31.1 | 42 | 19 | 14 | 2 | 8 | 19 | 2 | 0 | 0 | 1.60 | 12.06 | 0.57 | 2.30 | 5.46 | 5.46 | 2.38 | premium | premium | premium | AAA | 2005-2011 | 2010 | ||
| 18 | Nelson Payano | 27 | L | 1 | 1 | 5.83 | 26 | 0 | 0 | 0 | 26 | 10 | 1 | 29.1 | 31 | 19 | 19 | 2 | 23 | 36 | 2 | 1 | 1 | 1.84 | 9.51 | 0.61 | 7.06 | 11.05 | 5.83 | 1.57 | premium | premium | premium | AAA | 2003-2014 | 2010 | ||
| 43 | Bubbie Buzachero | 29 | R | 1 | 1 | 4.23 | 8 | 3 | 0 | 0 | 5 | 0 | 0 | 27.2 | 25 | 13 | 13 | 0 | 7 | 15 | 0 | 2 | 2 | 1.16 | 8.13 | 0.00 | 2.28 | 4.88 | 4.23 | 2.14 | 2002- 23- 686-TOR | premium | premium | premium | AAA | 2000-2012 | 2010 | |
| 33 | Evan Englebrook | 28 | R | 0 | 2 | 2.96 | 23 | 0 | 0 | 0 | 23 | 17 | 4 | 27.1 | 25 | 10 | 9 | 3 | 7 | 22 | 1 | 0 | 0 | 1.17 | 8.23 | 0.99 | 2.30 | 7.24 | 3.29 | 3.14 | 2004- 8- 244-HOU | premium | premium | premium | AAA | 2001-2015 | 2010 | |
| 26 | Edwin Walker | 26 | L | 4 | 1 | 2.84 | 19 | 0 | 0 | 0 | 19 | 5 | 0 | 25.1 | 23 | 9 | 8 | 0 | 14 | 21 | 2 | 1 | 2 | 1.46 | 8.17 | 0.00 | 4.97 | 7.46 | 3.20 | 1.50 | 2002- 9- 259-MIL | premium | premium | premium | AA | 2002-2013 | 2010 | |
| 32 | Erik Stiller | 25 | R | 0 | 0 | 4.81 | 15 | 0 | 0 | 0 | 15 | 5 | 0 | 24.1 | 24 | 13 | 13 | 7 | 5 | 17 | 1 | 0 | 0 | 1.19 | 8.88 | 2.59 | 1.85 | 6.29 | 4.81 | 3.40 | premium | premium | premium | AA | 2003-2010 | 2010 | ||
| - | Arcenio Leon | 23 | R | 0 | 2 | 7.83 | 18 | 0 | 0 | 0 | 18 | 5 | 0 | 23.0 | 29 | 20 | 20 | 3 | 22 | 23 | 6 | 0 | 3 | 2.22 | 11.35 | 1.17 | 8.61 | 9.00 | 7.83 | 1.05 | 2005- UDFA -HOU | premium | premium | premium | MLB | 2017-2017 | 2007-2021 | 2010 |
| 16 | Chia-Jen Lo | 24 | R | 0 | 1 | 1.80 | 7 | 0 | 0 | 0 | 7 | 0 | 0 | 15.0 | 9 | 3 | 3 | 0 | 10 | 13 | 4 | 0 | 1 | 1.27 | 5.40 | 0.00 | 6.00 | 7.80 | 1.80 | 1.30 | 2008- UDFA -HOU | premium | premium | premium | MLB | 2013-2013 | 2009-2014 | 2010 |
| 35 | Douglas Arguello | 25 | L | 7 | 5 | 2.55 | 22 | 22 | 2 | 0 | 0 | 0 | 0 | 127.0 | 120 | 50 | 36 | 4 | 47 | 100 | 9 | 1 | 9 | 1.31 | 8.50 | 0.28 | 3.33 | 7.09 | 3.54 | 2.13 | premium | premium | premium | AAA | 2003-2014 | 2010 | ||
| 23 | Jordan Lyles | 19 | R | 7 | 9 | 3.12 | 21 | 20 | 1 | 0 | 1 | 0 | 0 | 127.0 | 133 | 54 | 44 | 10 | 35 | 115 | 3 | 1 | 5 | 1.32 | 9.43 | 0.71 | 2.48 | 8.15 | 3.83 | 3.29 | 2008- 1- 38-HOU | premium | premium | premium | MLB | 2011-2024 | 2008-2024 | 2010 |
| 37 | Jose G. Valdez | 27 | R | 0 | 0 | 1.46 | 9 | 0 | 0 | 0 | 9 | 6 | 0 | 12.1 | 5 | 2 | 2 | 0 | 4 | 11 | 0 | 0 | 2 | 0.73 | 3.65 | 0.00 | 2.92 | 8.03 | 1.46 | 2.75 | 2014- UDFA -NYA | premium | premium | premium | MLB | 2011-2012 | 2002-2015 | 2010 |
| 44 | Jeremy Johnson | 27 | R | 5 | 10 | 4.30 | 22 | 22 | 1 | 0 | 0 | 0 | 0 | 111.0 | 128 | 61 | 53 | 13 | 42 | 72 | 6 | 0 | 1 | 1.53 | 10.38 | 1.05 | 3.41 | 5.84 | 4.95 | 1.71 | 2000- 11- 318-DET | premium | premium | premium | AAA | 2000-2010 | 2010 | |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 31 | Henry Villar | 23 | R | 4 | 7 | 4.15 | 36 | 11 | 0 | 0 | 25 | 9 | 5 | 102.0 | 95 | 49 | 47 | 11 | 42 | 68 | 2 | 1 | 2 | 1.34 | 8.38 | 0.97 | 3.71 | 6.00 | 4.32 | 1.62 | 2005- UDFA -HOU | premium | premium | premium | MLB | 2010-2010 | 2008-2014 | 2010 |
| 13 | Brian Wabick | 22 | R | 1 | 0 | 7.84 | 6 | 0 | 0 | 0 | 6 | 1 | 0 | 10.1 | 20 | 10 | 9 | 1 | 4 | 2 | 0 | 0 | 0 | 2.32 | 17.42 | 0.87 | 3.48 | 1.74 | 8.71 | 0.50 | 2007- 34-1038-HOU | premium | premium | premium | AA | 2007-2010 | 2010 | |
| - | Matt Lindstrom | 30 | R | 0 | 0 | 0.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0.00 | 0.00 | 0.00 | 0.00 | 9.00 | 0.00 | 0.00 | 2002- 10- 297-NYN | premium | premium | premium | MLB | 2007-2014 | 2002-2015 | 2010 |
| - | Chris Sampson | 32 | R | 0 | 0 | 0.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1.00 | 0.00 | 0.00 | 9.00 | 9.00 | 0.00 | 1.00 | 1999- 8- 263-HOU | premium | premium | premium | MLB | 2006-2010 | 1999-2011 | 2010 |
| Totals: | 63 | 77 | 3.65 | 459 | 140 | 5 | 0 | 135 | 319 | 27 | 1234.2 | 1238 | 581 | 501 | 89 | 498 | 949 | 69 | 12 | 43 | 1.41 | 9.02 | 0.65 | 3.63 | 6.92 | 4.24 | 1.91 | premium | premium | premium |