| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 51 | Wes Hodges | 25 | 1B | R | 99 | 125 | 493 | 65 | 133 | 28 | 3 | 15 | 60 | 2 | 0 | 30 | 96 | 0 | 2 | 6 | 0 | 19 | 212 | 531 | 46 | 87 | .270 | .308 | .430 | .738 | .225 | .160 | .304 | 5.65 | 18.08 | 3.20 | 32.87 | 2006- 2- 69-CLE | premium | premium | premium | AAA | 2004-2012 | 2010 | |
| 12 | Jose Constanza | 26 | RF-CF | L | 107 | 113 | 404 | 69 | 129 | 11 | 8 | 1 | 32 | 34 | 6 | 35 | 54 | 0 | 8 | 1 | 1 | 7 | 159 | 448 | 20 | 109 | .319 | .373 | .394 | .767 | .230 | .075 | .366 | 7.81 | 12.05 | 1.54 | 404.00 | 2003- UDFA -CLE | premium | premium | premium | MLB | 2011-2014 | 2005-2017 | 2010 |
| 9 | Jordan Brown | 26 | LF-RF | L | 107 | 83 | 326 | 31 | 97 | 28 | 1 | 8 | 67 | 2 | 0 | 21 | 48 | 3 | 0 | 5 | 1 | 9 | 151 | 355 | 37 | 60 | .298 | .341 | .463 | .804 | .236 | .165 | .324 | 5.92 | 13.52 | 2.29 | 40.75 | 2005- 4- 124-CLE | premium | premium | premium | MLB | 2010-2013 | 2003-2014 | 2010 |
| 25 | Jared Goedert | 25 | 3B | R | 116 | 81 | 318 | 54 | 83 | 23 | 1 | 20 | 51 | 2 | 0 | 37 | 77 | 5 | 0 | 2 | 0 | 15 | 168 | 362 | 44 | 39 | .261 | .345 | .528 | .873 | .390 | .267 | .283 | 10.22 | 21.27 | 2.08 | 15.90 | 2006- 9- 281-CLE | premium | premium | premium | AAA | 2005-2014 | 2010 | |
| 7 | Joshua Rodriguez | 25 | SS | R | 115 | 86 | 317 | 49 | 93 | 23 | 1 | 12 | 46 | 6 | 2 | 40 | 75 | 1 | 4 | 2 | 1 | 16 | 154 | 364 | 36 | 57 | .293 | .372 | .486 | .858 | .331 | .193 | .349 | 10.99 | 20.60 | 1.88 | 26.42 | 2006- 2- 57-CLE | premium | premium | premium | MLB | 2011-2011 | 2004-2024 | 2010 |
| 23 | Michael Brantley | 23 | CF-LF | L | 112 | 67 | 273 | 54 | 87 | 13 | 2 | 4 | 29 | 13 | 5 | 34 | 28 | 2 | 5 | 2 | 1 | 7 | 116 | 316 | 19 | 68 | .319 | .395 | .425 | .820 | .260 | .106 | .342 | 10.76 | 8.86 | 0.82 | 68.25 | 2005- 7- 205-MIL | premium | premium | premium | MLB | 2009-2023 | 2005-2023 | 2010 |
| 26 | Cord Phelps | 23 | 2B | B | 118 | 66 | 243 | 41 | 77 | 20 | 4 | 6 | 31 | 3 | 2 | 24 | 39 | 4 | 1 | 1 | 1 | 3 | 123 | 273 | 30 | 47 | .317 | .386 | .506 | .892 | .292 | .189 | .357 | 8.79 | 14.29 | 1.63 | 40.50 | 2008- 3- 107-CLE | premium | premium | premium | MLB | 2011-2014 | 2006-2015 | 2010 |
| 15 | Brian Bixler | 27 | SS-3B | R | 100 | 64 | 230 | 32 | 64 | 13 | 1 | 3 | 27 | 9 | 4 | 20 | 46 | 5 | 1 | 3 | 1 | 8 | 88 | 259 | 17 | 47 | .278 | .345 | .383 | .728 | .213 | .105 | .332 | 7.72 | 17.76 | 2.30 | 76.67 | 2004- 2- 52-PIT | premium | premium | premium | MLB | 2008-2012 | 2002-2014 | 2010 |
| 41 | Carlos Santana | 24 | C | B | 137 | 57 | 196 | 39 | 62 | 14 | 1 | 13 | 51 | 6 | 0 | 45 | 39 | 3 | 0 | 2 | 4 | 5 | 117 | 246 | 28 | 34 | .316 | .447 | .597 | 1.044 | .541 | .281 | .336 | 18.29 | 15.85 | 0.87 | 15.08 | 2004- UDFA -LAN | premium | premium | premium | MLB | 2010-2025 | 2005-2025 | 2010 |
| 8 | Chris Gimenez | 27 | RF-C | R | 108 | 55 | 196 | 32 | 54 | 10 | 0 | 9 | 32 | 1 | 1 | 20 | 38 | 0 | 2 | 1 | 0 | 5 | 91 | 219 | 19 | 35 | .276 | .341 | .464 | .805 | .291 | .188 | .300 | 9.13 | 17.35 | 1.90 | 21.78 | 2004- 19- 557-CLE | premium | premium | premium | MLB | 2009-2018 | 2002-2018 | 2010 |
| 34 | Nick Weglarz | 22 | LF | L | 117 | 50 | 175 | 30 | 50 | 17 | 1 | 6 | 20 | 2 | 2 | 28 | 43 | 4 | 0 | 2 | 3 | 3 | 87 | 209 | 24 | 26 | .286 | .392 | .497 | .889 | .371 | .211 | .344 | 13.40 | 20.57 | 1.54 | 29.17 | 2005- 3- 94-CLE | premium | premium | premium | AAA | 2005-2013 | 2010 | |
| 43 | Anderson Hernandez | 27 | SS | B | 75 | 47 | 171 | 13 | 40 | 4 | 0 | 1 | 17 | 2 | 4 | 12 | 23 | 0 | 1 | 3 | 0 | 3 | 47 | 187 | 5 | 35 | .234 | .280 | .275 | .555 | .099 | .041 | .260 | 6.42 | 12.30 | 1.92 | 171.00 | 2001- UDFA -DET | premium | premium | premium | MLB | 2005-2010 | 2001-2018 | 2010 |
| 29 | Brian Buscher | 29 | 3B | L | 99 | 47 | 162 | 19 | 43 | 9 | 2 | 4 | 26 | 0 | 0 | 17 | 10 | 1 | 2 | 5 | 1 | 7 | 68 | 187 | 15 | 28 | .265 | .330 | .420 | .750 | .259 | .155 | .255 | 9.09 | 5.35 | 0.59 | 40.50 | 2003- 3- 93-SFN | premium | premium | premium | MLB | 2007-2009 | 2002-2010 | 2010 |
| 8 | Ezequiel Carrera | 23 | CF | L | 100 | 41 | 161 | 19 | 46 | 7 | 3 | 1 | 16 | 11 | 3 | 12 | 34 | 1 | 8 | 1 | 0 | 5 | 62 | 183 | 11 | 35 | .286 | .337 | .385 | .722 | .224 | .099 | .354 | 6.56 | 18.58 | 2.83 | 161.00 | 2005- UDFA -NYN | premium | premium | premium | MLB | 2011-2017 | 2007-2019 | 2010 |
| 17 | Shelley Duncan | 30 | RF | R | 117 | 38 | 146 | 21 | 44 | 11 | 0 | 6 | 34 | 0 | 0 | 17 | 28 | 2 | 0 | 1 | 0 | 5 | 73 | 166 | 17 | 27 | .301 | .380 | .500 | .880 | .315 | .199 | .336 | 10.24 | 16.87 | 1.65 | 24.33 | 2001- 2- 62-NYA | premium | premium | premium | MLB | 2007-2013 | 1999-2014 | 2010 |
| 2 | Jason Donald | 25 | 2B | R | 115 | 37 | 137 | 27 | 38 | 10 | 2 | 2 | 17 | 10 | 2 | 21 | 33 | 6 | 1 | 0 | 0 | 3 | 58 | 165 | 14 | 24 | .277 | .396 | .423 | .819 | .358 | .146 | .353 | 12.73 | 20.00 | 1.57 | 68.50 | 2006- 3- 97-PHI | premium | premium | premium | MLB | 2010-2012 | 2004-2014 | 2010 |
| 2 | Lou Marson | 24 | C | R | 99* | 37 | 124 | 19 | 25 | 7 | 1 | 4 | 14 | 5 | 0 | 22 | 24 | 1 | 0 | 0 | 0 | 1 | 46 | 147 | 12 | 13 | .202 | .327 | .371 | .698 | .387 | .169 | .219 | 14.97 | 16.33 | 1.09 | 31.00 | 2004- 4- 122-PHI | premium | premium | premium | MLB | 2008-2013 | 2004-2015 | 2010 |
| 44 | Matt McBride | 25 | LF-1B | R | 96* | 31 | 119 | 16 | 32 | 6 | 0 | 4 | 11 | 0 | 0 | 5 | 17 | 0 | 2 | 1 | 0 | 4 | 50 | 127 | 10 | 22 | .269 | .296 | .420 | .716 | .193 | .151 | .283 | 3.94 | 13.39 | 3.40 | 29.75 | 2006- 2- 75-CLE | premium | premium | premium | MLB | 2012-2016 | 2004-2019 | 2010 |
| 10 | Trevor Crowe | 26 | RF-LF | B | 82* | 29 | 119 | 21 | 29 | 4 | 1 | 1 | 13 | 6 | 1 | 7 | 19 | 0 | 0 | 2 | 1 | 2 | 38 | 128 | 6 | 23 | .244 | .281 | .319 | .600 | .176 | .075 | .277 | 5.47 | 14.84 | 2.71 | 119.00 | 2005- 1- 14-CLE | premium | premium | premium | MLB | 2009-2013 | 2003-2014 | 2010 |
| 45 | Drew Sutton | 27 | LF-2B | B | 105 | 29 | 96 | 10 | 29 | 8 | 0 | 2 | 15 | 4 | 0 | 18 | 21 | 1 | 3 | 1 | 0 | 2 | 43 | 119 | 10 | 19 | .302 | .414 | .448 | .862 | .375 | .146 | .365 | 15.13 | 17.65 | 1.17 | 48.00 | 2004- 15- 454-HOU | premium | premium | premium | MLB | 2009-2012 | 2004-2013 | 2010 |
| 6 | Luis Valbuena | 24 | SS-3B | L | 136* | 25 | 96 | 23 | 30 | 8 | 1 | 6 | 20 | 2 | 0 | 19 | 21 | 1 | 2 | 1 | 0 | 2 | 58 | 119 | 15 | 15 | .313 | .427 | .604 | 1.031 | .510 | .291 | .343 | 15.97 | 17.65 | 1.11 | 16.00 | 2002- UDFA -SEA | premium | premium | premium | MLB | 2008-2018 | 2005-2018 | 2010 |
| 2 | Damaso Espino | 27 | C | R | 85* | 26 | 80 | 7 | 20 | 2 | 0 | 0 | 11 | 0 | 0 | 10 | 10 | 0 | 1 | 2 | 0 | 5 | 22 | 93 | 2 | 18 | .250 | .326 | .275 | .601 | .150 | .025 | .278 | 10.75 | 10.75 | 1.00 | 0.00 | 1999- UDFA -CIN | premium | premium | premium | AAA | 2000-2014 | 2010 | |
| 9 | Jerad Head | 27 | LF | R | 21 | 74 | 12 | 19 | 9 | 0 | 2 | 15 | 0 | 0 | 5 | 20 | 3 | 0 | 1 | 0 | 4 | 34 | 83 | 11 | 8 | .257 | .325 | .459 | .784 | .270 | .202 | .321 | 6.02 | 24.10 | 4.00 | 37.00 | 2005- UDFA -CLE | premium | premium | premium | MLB | 2011-2011 | 2002-2013 | 2010 | |
| 7 | Matt LaPorta | 25 | LF-1B | R | 18 | 69 | 7 | 25 | 4 | 0 | 5 | 16 | 0 | 1 | 12 | 10 | 0 | 0 | 0 | 0 | 2 | 44 | 81 | 9 | 16 | .362 | .457 | .638 | 1.095 | .435 | .276 | .370 | 14.81 | 12.35 | 0.83 | 13.80 | 2007- 1- 7-MIL | premium | premium | premium | MLB | 2009-2012 | 2004-2014 | 2010 | |
| 11 | Argenis Reyes | 27 | 3B-2B | B | 94* | 16 | 53 | 5 | 18 | 2 | 0 | 0 | 4 | 0 | 0 | 1 | 5 | 1 | 0 | 0 | 0 | 1 | 20 | 55 | 2 | 16 | .340 | .364 | .377 | .741 | .057 | .037 | .375 | 1.82 | 9.09 | 5.00 | 0.00 | 2001- UDFA -CLE | premium | premium | premium | MLB | 2008-2009 | 2003-2011 | 2010 |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 43 | Wyatt Toregas | 27 | C | R | 14 | 50 | 3 | 10 | 1 | 0 | 2 | 6 | 0 | 0 | 1 | 9 | 1 | 0 | 1 | 0 | 3 | 17 | 53 | 3 | 7 | .200 | .226 | .340 | .566 | .160 | .140 | .200 | 1.89 | 16.98 | 9.00 | 25.00 | 2004- 24- 707-CLE | premium | premium | premium | MLB | 2009-2011 | 2002-2011 | 2010 | |
| 6 | Luke Carlin | 29 | C | B | 93 | 13 | 39 | 9 | 9 | 2 | 0 | 2 | 6 | 0 | 0 | 7 | 11 | 0 | 1 | 1 | 0 | 0 | 17 | 48 | 4 | 5 | .231 | .340 | .436 | .776 | .385 | .205 | .259 | 14.58 | 22.92 | 1.57 | 19.50 | 2002- 10- 290-DET | premium | premium | premium | MLB | 2008-2012 | 2000-2015 | 2010 |
| 25 | Josh Phelps | 32 | RF-1B | R | 6 | 21 | 1 | 4 | 3 | 0 | 0 | 2 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 7 | 21 | 3 | 1 | .190 | .190 | .333 | .523 | .143 | .143 | .286 | 0.00 | 33.33 | 0.00 | 0.00 | 1996- 10- 279-TOR | premium | premium | premium | MLB | 2000-2008 | 1996-2010 | 2010 | |
| 43 | Richard Martinez | 23 | C | R | 5 | 17 | 1 | 6 | 3 | 0 | 0 | 6 | 0 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 9 | 20 | 3 | 3 | .353 | .450 | .529 | .979 | .353 | .176 | .462 | 15.00 | 20.00 | 1.33 | 0.00 | premium | premium | premium | AAA | 2006-2010 | 2010 | |||
| 9 | Brian Horwitz | 27 | RF-LF | R | 6 | 15 | 1 | 4 | 2 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 2 | 6 | 18 | 2 | 2 | .267 | .333 | .400 | .733 | .200 | .133 | .250 | 5.56 | 0.00 | 0.00 | 0.00 | 2003- 26- 782-OAK | premium | premium | premium | MLB | 2008-2008 | 2001-2010 | 2010 | |
| - | Russell Branyan | 34 | 1B | L | 4 | 14 | 1 | 4 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 1 | 6 | 15 | 2 | 2 | .286 | .333 | .429 | .762 | .214 | .143 | .333 | 6.67 | 13.33 | 2.00 | 0.00 | 1994- 7- 185-CLE | premium | premium | premium | MLB | 1998-2011 | 1994-2014 | 2010 | |
| - | Kyle Smith | 22 | SS | R | 4 | 10 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 2 | 0 | 0 | 0 | 0 | 3 | 13 | 0 | 3 | .300 | .462 | .300 | .762 | .100 | .000 | .429 | 7.69 | 23.08 | 3.00 | 0.00 | 2009- 14- 425-CLE | premium | premium | premium | AAA | 2007-2011 | 2010 | ||
| - | Justin Toole | 23 | 3B-2B | R | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2009- UDFA -CLE | premium | premium | premium | AAA | 2006-2015 | 2010 | ||
| Totals: | 1342 | 4945 | 731 | 1407 | 304 | 33 | 139 | 699 | 120 | 33 | 526 | 895 | 48 | 44 | 48 | 15 | 149 | 2194 | 5611 | 476 | 931 | .285 | .356 | .444 | .800 | .283 | .159 | .320 | 9.37 | 15.95 | 1.70 | 35.58 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| - | Hector Ambriz | 26 | R | 0 | 0 | 1.13 | 7 | 0 | 0 | 0 | 7 | 0 | 0 | 8.0 | 9 | 1 | 1 | 0 | 1 | 15 | 1 | 0 | 0 | 1.25 | 10.13 | 0.00 | 1.13 | 16.88 | 1.13 | 15.00 | 2006- 5- 147-ARI | premium | premium | premium | MLB | 2010-2014 | 2003-2019 | 2010 |
| 24 | David Huff | 25 | L | 8 | 2 | 4.36 | 12 | 12 | 0 | 0 | 0 | 0 | 0 | 74.1 | 84 | 37 | 36 | 8 | 21 | 52 | 3 | 0 | 2 | 1.41 | 10.17 | 0.97 | 2.54 | 6.30 | 4.48 | 2.48 | 2006- 1- 39-CLE | premium | premium | premium | MLB | 2009-2016 | 2004-2024 | 2010 |
| 17 | Justin Germano | 27 | R | 3 | 2 | 3.38 | 17 | 6 | 1 | 1 | 11 | 5 | 1 | 53.1 | 49 | 23 | 20 | 8 | 10 | 37 | 2 | 0 | 1 | 1.11 | 8.27 | 1.35 | 1.69 | 6.24 | 3.88 | 3.70 | 2000- 13- 379-SDN | premium | premium | premium | MLB | 2004-2014 | 2000-2015 | 2010 |
| 13 | Jeremy Sowers | 27 | L | 2 | 6 | 5.85 | 27 | 4 | 0 | 0 | 23 | 6 | 0 | 52.1 | 55 | 38 | 34 | 2 | 18 | 29 | 3 | 0 | 1 | 1.39 | 9.46 | 0.34 | 3.10 | 4.99 | 6.54 | 1.61 | 2004- 1- 6-CLE | premium | premium | premium | MLB | 2006-2009 | 2002-2013 | 2010 |
| 35 | Jess Todd | 24 | R | 4 | 2 | 3.31 | 44 | 0 | 0 | 0 | 44 | 18 | 4 | 49.0 | 46 | 20 | 18 | 6 | 18 | 53 | 1 | 0 | 3 | 1.31 | 8.45 | 1.10 | 3.31 | 9.73 | 3.67 | 2.94 | 2007- 2- 82-SLN | premium | premium | premium | MLB | 2009-2010 | 2007-2015 | 2010 |
| 36 | Carlton Smith | 24 | R | 1 | 5 | 6.38 | 37 | 0 | 0 | 0 | 37 | 11 | 1 | 48.0 | 66 | 36 | 34 | 7 | 20 | 30 | 5 | 1 | 4 | 1.79 | 12.38 | 1.31 | 3.75 | 5.63 | 6.75 | 1.50 | 2004- 21- 617-CLE | premium | premium | premium | AAA | 2005-2013 | 2010 | |
| 10 | Josh Judy | 24 | R | 3 | 0 | 2.68 | 38 | 0 | 0 | 0 | 38 | 14 | 2 | 47.0 | 48 | 18 | 14 | 5 | 14 | 55 | 1 | 0 | 0 | 1.32 | 9.19 | 0.96 | 2.68 | 10.53 | 3.45 | 3.93 | 2007- 34-1034-CLE | premium | premium | premium | MLB | 2011-2011 | 2007-2019 | 2010 |
| 27 | Vinnie Pestano | 25 | R | 1 | 2 | 1.55 | 43 | 0 | 0 | 0 | 43 | 30 | 14 | 46.1 | 35 | 10 | 8 | 1 | 14 | 59 | 1 | 0 | 1 | 1.06 | 6.80 | 0.19 | 2.72 | 11.46 | 1.94 | 4.21 | 2006- 20- 611-CLE | premium | premium | premium | MLB | 2010-2015 | 2004-2018 | 2010 |
| 17 | Paolo Espino | 23 | R | 3 | 3 | 5.62 | 7 | 7 | 0 | 0 | 0 | 0 | 0 | 41.2 | 43 | 26 | 26 | 7 | 12 | 32 | 2 | 0 | 2 | 1.32 | 9.29 | 1.51 | 2.59 | 6.91 | 5.62 | 2.67 | 2006- 10- 311-CLE | premium | premium | premium | MLB | 2017-2024 | 2007-2025 | 2010 |
| - | Marty Popham | 22 | R | 0 | 1 | 13.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 4.0 | 9 | 6 | 6 | 1 | 3 | 2 | 0 | 0 | 1 | 3.00 | 20.25 | 2.25 | 6.75 | 4.50 | 13.50 | 0.67 | 2009- 17- 531-ANA | premium | premium | premium | AAA | 2008-2013 | 2010 | |
| 40 | Hector Rondon | 22 | R | 1 | 3 | 8.53 | 7 | 7 | 0 | 0 | 0 | 0 | 0 | 31.2 | 48 | 32 | 30 | 12 | 10 | 33 | 0 | 0 | 2 | 1.83 | 13.64 | 3.41 | 2.84 | 9.38 | 9.09 | 3.30 | 2004- UDFA -CLE | premium | premium | premium | MLB | 2013-2020 | 2006-2020 | 2010 |
| 41 | Jensen Lewis | 26 | R | 2 | 1 | 2.67 | 24 | 0 | 0 | 0 | 24 | 8 | 2 | 30.1 | 29 | 9 | 9 | 2 | 8 | 30 | 0 | 0 | 1 | 1.22 | 8.60 | 0.59 | 2.37 | 8.90 | 2.67 | 3.75 | 2005- 3- 102-CLE | premium | premium | premium | MLB | 2007-2010 | 2003-2013 | 2010 |
| 45 | Frank Herrmann | 26 | R | 3 | 0 | 0.31 | 19 | 0 | 0 | 0 | 19 | 4 | 2 | 28.2 | 15 | 1 | 1 | 0 | 8 | 22 | 1 | 0 | 0 | 0.80 | 4.71 | 0.00 | 2.51 | 6.91 | 0.31 | 2.75 | 2005- UDFA -CLE | premium | premium | premium | MLB | 2010-2016 | 2003-2021 | 2010 |
| 34 | Mike Gosling | 29 | L | 3 | 0 | 2.96 | 13 | 2 | 0 | 0 | 11 | 4 | 0 | 27.1 | 22 | 10 | 9 | 2 | 9 | 24 | 2 | 0 | 1 | 1.13 | 7.24 | 0.66 | 2.96 | 7.90 | 3.29 | 2.67 | 2001- 2- 66-ARI | premium | premium | premium | MLB | 2004-2009 | 1999-2010 | 2010 |
| 29 | Aaron Laffey | 25 | L | 0 | 1 | 3.67 | 10 | 4 | 0 | 0 | 6 | 1 | 0 | 27.0 | 29 | 11 | 11 | 1 | 16 | 12 | 1 | 0 | 0 | 1.67 | 9.67 | 0.33 | 5.33 | 4.00 | 3.67 | 0.75 | 2003- 16- 468-CLE | premium | premium | premium | MLB | 2007-2015 | 2003-2018 | 2010 |
| 29 | Eric Berger | 24 | L | 0 | 1 | 5.84 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 24.2 | 31 | 18 | 16 | 2 | 20 | 17 | 1 | 0 | 1 | 2.07 | 11.31 | 0.73 | 7.30 | 6.20 | 6.57 | 0.85 | 2008- 8- 261-CLE | premium | premium | premium | AAA | 2005-2015 | 2010 | |
| 28 | Zach Putnam | 22 | R | 0 | 1 | 3.33 | 17 | 0 | 0 | 0 | 17 | 5 | 0 | 24.1 | 20 | 10 | 9 | 2 | 7 | 24 | 1 | 0 | 0 | 1.11 | 7.40 | 0.74 | 2.59 | 8.88 | 3.70 | 3.43 | 2008- 5- 171-CLE | premium | premium | premium | MLB | 2011-2017 | 2006-2017 | 2010 |
| 52 | Saul Rivera | 32 | R | 2 | 1 | 1.50 | 21 | 0 | 0 | 0 | 21 | 20 | 5 | 24.0 | 13 | 5 | 4 | 0 | 12 | 14 | 3 | 0 | 0 | 1.04 | 4.88 | 0.00 | 4.50 | 5.25 | 1.88 | 1.17 | 1998- 9- 259-MIN | premium | premium | premium | MLB | 2006-2010 | 1997-2012 | 2010 |
| 38 | Joe Smith | 26 | R | 2 | 1 | 1.96 | 20 | 0 | 0 | 0 | 20 | 4 | 2 | 23.0 | 17 | 8 | 5 | 0 | 10 | 19 | 2 | 0 | 0 | 1.17 | 6.65 | 0.00 | 3.91 | 7.43 | 3.13 | 1.90 | 2006- 3- 94-NYN | premium | premium | premium | MLB | 2007-2022 | 2004-2022 | 2010 |
| 23 | Bryce Stowell | 23 | R | 1 | 1 | 5.49 | 17 | 0 | 0 | 0 | 17 | 3 | 0 | 19.2 | 11 | 12 | 12 | 2 | 17 | 28 | 2 | 1 | 1 | 1.42 | 5.03 | 0.92 | 7.78 | 12.81 | 5.49 | 1.65 | 2008- 22- 681-CLE | premium | premium | premium | AAA | 2006-2015 | 2010 | |
| 34 | Zach McAllister | 22 | R | 1 | 2 | 6.88 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 17.0 | 20 | 13 | 13 | 1 | 7 | 11 | 0 | 0 | 1 | 1.59 | 10.59 | 0.53 | 3.71 | 5.82 | 6.88 | 1.57 | 2006- 3- 104-NYA | premium | premium | premium | MLB | 2011-2023 | 2006-2023 | 2010 |
| 27 | Scott Lewis | 26 | L | 2 | 0 | 2.12 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 17.0 | 12 | 6 | 4 | 1 | 4 | 18 | 1 | 0 | 1 | 0.94 | 6.35 | 0.53 | 2.12 | 9.53 | 3.18 | 4.50 | 2004- 3- 77-CLE | premium | premium | premium | MLB | 2008-2009 | 2002-2010 | 2010 |
| 47 | Carlos Carrasco | 23 | R | 10 | 6 | 3.65 | 25 | 25 | 0 | 0 | 0 | 0 | 0 | 150.1 | 139 | 69 | 61 | 16 | 46 | 133 | 1 | 0 | 7 | 1.23 | 8.32 | 0.96 | 2.75 | 7.96 | 4.13 | 2.89 | 2003- UDFA -PHI | premium | premium | premium | MLB | 2009-2025 | 2004-2025 | 2010 |
| 39 | Yohan Pino | 26 | R | 10 | 9 | 5.75 | 26 | 26 | 1 | 0 | 0 | 0 | 0 | 145.2 | 175 | 101 | 93 | 25 | 47 | 114 | 3 | 0 | 9 | 1.52 | 10.81 | 1.54 | 2.90 | 7.04 | 6.24 | 2.43 | 2004- UDFA -MIN | premium | premium | premium | MLB | 2014-2015 | 2005-2017 | 2010 |
| 44 | Jeanmar Gomez | 22 | R | 8 | 8 | 5.20 | 20 | 20 | 1 | 0 | 0 | 0 | 0 | 116.0 | 129 | 74 | 67 | 16 | 42 | 78 | 8 | 1 | 1 | 1.47 | 10.01 | 1.24 | 3.26 | 6.05 | 5.74 | 1.86 | 2005- UDFA -CLE | premium | premium | premium | MLB | 2010-2019 | 2006-2019 | 2010 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 38 | Shane Lindsay | 25 | R | 0 | 1 | 8.18 | 7 | 0 | 0 | 0 | 7 | 2 | 0 | 11.0 | 13 | 11 | 10 | 1 | 16 | 12 | 4 | 0 | 2 | 2.64 | 10.64 | 0.82 | 13.09 | 9.82 | 9.00 | 0.75 | 2003- UDFA -COL | premium | premium | premium | MLB | 2011-2011 | 2004-2012 | 2010 |
| - | Corey Kluber | 24 | R | 1 | 1 | 3.27 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 11.0 | 10 | 4 | 4 | 1 | 6 | 8 | 0 | 0 | 2 | 1.45 | 8.18 | 0.82 | 4.91 | 6.55 | 3.27 | 1.33 | 2007- 4- 134-SDN | premium | premium | premium | MLB | 2011-2023 | 2005-2023 | 2010 |
| 24 | Josh Tomlin | 25 | R | 8 | 4 | 2.68 | 20 | 17 | 1 | 0 | 3 | 0 | 0 | 107.1 | 83 | 34 | 32 | 11 | 33 | 80 | 4 | 0 | 2 | 1.08 | 6.96 | 0.92 | 2.77 | 6.71 | 2.85 | 2.42 | 2006- 19- 581-CLE | premium | premium | premium | MLB | 2010-2021 | 2006-2021 | 2010 |
| 25 | Steven Wright | 25 | R | 0 | 1 | 7.59 | 9 | 0 | 0 | 0 | 9 | 4 | 0 | 10.2 | 13 | 9 | 9 | 2 | 5 | 10 | 0 | 0 | 0 | 1.69 | 10.97 | 1.69 | 4.22 | 8.44 | 7.59 | 2.00 | 2006- 2- 56-CLE | premium | premium | premium | MLB | 2013-2019 | 2004-2021 | 2010 |
| - | Francisco Jimenez | 21 | L | 0 | 0 | 27.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.2 | 8 | 6 | 5 | 0 | 1 | 0 | 1 | 0 | 0 | 5.40 | 43.20 | 0.00 | 5.40 | 0.00 | 32.40 | 0.00 | 2007- UDFA -CLE | premium | premium | premium | AAA | 2009-2013 | 2010 | |
| - | Brian Buscher | 29 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2003- 3- 93-SFN | premium | premium | premium | MLB | 2007-2009 | 2002-2010 | 2010 |
| Totals: | 79 | 65 | 4.25 | 503 | 144 | 4 | 1 | 140 | 359 | 33 | 1273.1 | 1281 | 658 | 601 | 142 | 455 | 1051 | 54 | 3 | 46 | 1.36 | 9.05 | 1.00 | 3.22 | 7.43 | 4.65 | 2.31 | premium | premium | premium |