| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 5 | Carlos Gonzalez | 24 | LF-CF | L | 130 | 145 | 587 | 111 | 197 | 34 | 9 | 34 | 117 | 26 | 8 | 40 | 135 | 2 | 0 | 7 | 8 | 9 | 351 | 636 | 77 | 120 | .336 | .376 | .598 | .974 | .361 | .262 | .384 | 6.29 | 21.23 | 3.38 | 17.26 | 2002- UDFA -ARI | premium | premium | premium | MLB | 2008-2019 | 2003-2019 | 2010 |
| 2 | Troy Tulowitzki | 25 | SS | R | 127 | 122 | 470 | 89 | 148 | 32 | 3 | 27 | 95 | 11 | 2 | 48 | 78 | 5 | 1 | 5 | 4 | 17 | 267 | 529 | 62 | 86 | .315 | .381 | .568 | .949 | .374 | .253 | .327 | 9.07 | 14.74 | 1.63 | 17.41 | 2005- 1- 7-COL | premium | premium | premium | MLB | 2006-2019 | 2003-2019 | 2010 |
| 24 | Dexter Fowler | 24 | CF | B | 105 | 132 | 439 | 73 | 114 | 20 | 14 | 6 | 36 | 13 | 7 | 57 | 104 | 2 | 7 | 0 | 0 | 5 | 180 | 505 | 40 | 74 | .260 | .347 | .410 | .757 | .294 | .150 | .328 | 11.29 | 20.59 | 1.82 | 73.17 | 2004- 14- 410-COL | premium | premium | premium | MLB | 2008-2021 | 2005-2022 | 2010 |
| 17 | Todd Helton | 36 | 1B | L | 102 | 118 | 398 | 48 | 102 | 18 | 1 | 8 | 37 | 0 | 0 | 67 | 90 | 2 | 0 | 6 | 3 | 10 | 146 | 473 | 27 | 75 | .256 | .362 | .367 | .729 | .279 | .111 | .307 | 14.16 | 19.03 | 1.34 | 49.75 | 1995- 1- 8-COL | premium | premium | premium | MLB | 1997-2013 | 1993-2013 | 2010 |
| 21 | Miguel Olivo | 31 | C | R | 102 | 112 | 394 | 55 | 106 | 17 | 6 | 14 | 58 | 7 | 4 | 27 | 117 | 1 | 2 | 3 | 5 | 6 | 177 | 427 | 37 | 69 | .269 | .315 | .449 | .764 | .256 | .180 | .346 | 6.32 | 27.40 | 4.33 | 28.14 | 1996- UDFA -OAK | premium | premium | premium | MLB | 2002-2014 | 1998-2017 | 2010 |
| 12 | Clint Barmes | 31 | 2B-SS | R | 89 | 133 | 387 | 43 | 91 | 21 | 0 | 8 | 50 | 3 | 2 | 35 | 66 | 5 | 2 | 3 | 10 | 5 | 136 | 432 | 29 | 62 | .235 | .305 | .351 | .656 | .209 | .116 | .263 | 8.10 | 15.28 | 1.89 | 48.38 | 2000- 10- 287-COL | premium | premium | premium | MLB | 2003-2015 | 2000-2016 | 2010 |
| 9 | Ian Stewart | 25 | 3B | L | 105 | 121 | 386 | 54 | 99 | 14 | 2 | 18 | 61 | 5 | 2 | 45 | 110 | 5 | 0 | 5 | 8 | 8 | 171 | 441 | 34 | 65 | .256 | .338 | .443 | .781 | .311 | .187 | .308 | 10.20 | 24.94 | 2.44 | 21.44 | 2003- 1- 10-COL | premium | premium | premium | MLB | 2007-2014 | 2003-2015 | 2010 |
| 7 | Seth Smith | 27 | LF | L | 106 | 133 | 358 | 55 | 88 | 19 | 5 | 17 | 52 | 2 | 1 | 35 | 67 | 2 | 0 | 3 | 1 | 5 | 168 | 398 | 41 | 47 | .246 | .314 | .469 | .783 | .324 | .223 | .256 | 8.79 | 16.83 | 1.91 | 21.06 | 2004- 2- 50-COL | premium | premium | premium | MLB | 2007-2017 | 2002-2017 | 2010 |
| 19 | Ryan Spilborghs | 30 | RF-LF | R | 109 | 134 | 341 | 41 | 95 | 20 | 2 | 10 | 39 | 4 | 5 | 39 | 83 | 5 | 2 | 1 | 0 | 7 | 149 | 388 | 32 | 63 | .279 | .360 | .437 | .797 | .270 | .158 | .341 | 10.05 | 21.39 | 2.13 | 34.10 | 2002- 7- 201-COL | premium | premium | premium | MLB | 2005-2011 | 2000-2013 | 2010 |
| 6 | Melvin Mora | 38 | 3B | R | 107 | 113 | 316 | 39 | 90 | 12 | 5 | 7 | 45 | 2 | 1 | 31 | 53 | 5 | 2 | 0 | 2 | 9 | 133 | 354 | 24 | 66 | .285 | .358 | .421 | .779 | .237 | .136 | .324 | 8.76 | 14.97 | 1.71 | 45.14 | 1991- UDFA -HOU | premium | premium | premium | MLB | 1999-2011 | 1992-2011 | 2010 |
| 11 | Brad Hawpe | 31 | RF | L | 103 | 88 | 259 | 24 | 66 | 21 | 2 | 7 | 37 | 2 | 1 | 36 | 68 | 1 | 0 | 4 | 4 | 4 | 112 | 300 | 30 | 36 | .255 | .343 | .432 | .775 | .320 | .177 | .314 | 12.00 | 22.67 | 1.89 | 37.00 | 2000- 11- 317-COL | premium | premium | premium | MLB | 2004-2013 | 1999-2013 | 2010 |
| 18 | Jonathan Herrera | 25 | 2B | B | 97 | 76 | 222 | 34 | 63 | 6 | 2 | 1 | 21 | 2 | 2 | 25 | 36 | 0 | 7 | 3 | 1 | 2 | 76 | 257 | 9 | 54 | .284 | .352 | .342 | .694 | .171 | .058 | .330 | 9.73 | 14.01 | 1.44 | 222.00 | 2002- UDFA -COL | premium | premium | premium | MLB | 2008-2015 | 2003-2017 | 2010 |
| 20 | Chris Iannetta | 27 | C | R | 98 | 61 | 188 | 20 | 37 | 6 | 1 | 9 | 27 | 1 | 0 | 30 | 48 | 4 | 0 | 1 | 2 | 4 | 72 | 223 | 16 | 21 | .197 | .318 | .383 | .701 | .351 | .186 | .212 | 13.45 | 21.52 | 1.60 | 20.89 | 2004- 4- 110-COL | premium | premium | premium | MLB | 2006-2019 | 2002-2019 | 2010 |
| 23 | Jason Giambi | 39 | 1B | L | 107 | 87 | 176 | 17 | 43 | 9 | 0 | 6 | 35 | 2 | 0 | 35 | 47 | 6 | 0 | 5 | 5 | 5 | 70 | 222 | 15 | 28 | .244 | .378 | .398 | .776 | .364 | .154 | .289 | 15.77 | 21.17 | 1.34 | 29.33 | 1992- 2- 58-OAK | premium | premium | premium | MLB | 1995-2014 | 1992-2014 | 2010 |
| 3 | Eric Young | 25 | 2B | B | 87* | 51 | 172 | 26 | 42 | 5 | 1 | 0 | 8 | 17 | 6 | 17 | 32 | 0 | 0 | 0 | 0 | 2 | 49 | 189 | 6 | 36 | .244 | .312 | .285 | .597 | .203 | .041 | .300 | 8.99 | 16.93 | 1.88 | 0.00 | 2003- 30- 887-COL | premium | premium | premium | MLB | 2009-2018 | 2004-2019 | 2010 |
| 38 | Ubaldo Jimenez | 26 | P | R | 32 | 77 | 5 | 8 | 0 | 0 | 0 | 4 | 0 | 0 | 2 | 18 | 0 | 4 | 0 | 0 | 0 | 8 | 83 | 0 | 8 | .104 | .127 | .104 | .231 | .026 | .000 | .136 | 2.41 | 21.69 | 9.00 | 0.00 | 2001- UDFA -COL | premium | premium | premium | MLB | 2006-2017 | 2002-2017 | 2010 | |
| 46 | Jason Hammel | 27 | P | R | 29 | 57 | 3 | 6 | 1 | 0 | 0 | 2 | 0 | 0 | 1 | 29 | 0 | 5 | 0 | 0 | 0 | 7 | 63 | 1 | 5 | .105 | .121 | .123 | .244 | .035 | .018 | .214 | 1.59 | 46.03 | 29.00 | 0.00 | 2002- 10- 284-TBA | premium | premium | premium | MLB | 2006-2018 | 2002-2018 | 2010 | |
| 29 | Jorge De La Rosa | 29 | P | L | 20 | 41 | 3 | 7 | 2 | 0 | 0 | 4 | 0 | 0 | 0 | 15 | 0 | 3 | 0 | 0 | 1 | 9 | 44 | 2 | 5 | .171 | .171 | .220 | .391 | .049 | .049 | .269 | 0.00 | 34.09 | 0.00 | 0.00 | 1998- UDFA -ARI | premium | premium | premium | MLB | 2004-2018 | 1999-2018 | 2010 | |
| 45 | Jhoulys Chacin | 22 | P | R | 26 | 40 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 9 | 0 | 4 | 0 | 0 | 0 | 3 | 45 | 0 | 3 | .075 | .098 | .075 | .173 | .025 | .000 | .097 | 2.22 | 20.00 | 9.00 | 0.00 | 2004- UDFA -COL | premium | premium | premium | MLB | 2009-2022 | 2007-2024 | 2010 | |
| 28 | Aaron Cook | 31 | P | R | 25 | 40 | 5 | 6 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 17 | 0 | 5 | 0 | 0 | 0 | 8 | 45 | 2 | 4 | .150 | .150 | .200 | .350 | .050 | .050 | .261 | 0.00 | 37.78 | 0.00 | 0.00 | 1997- 2- 70-COL | premium | premium | premium | MLB | 2002-2012 | 1997-2013 | 2010 | |
| 15 | Jay Payton | 37 | LF | R | 20 | 35 | 3 | 12 | 4 | 1 | 0 | 1 | 1 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 2 | 18 | 36 | 5 | 7 | .343 | .361 | .514 | .875 | .229 | .171 | .387 | 2.78 | 11.11 | 4.00 | 0.00 | 1994- 1- 29-NYN | premium | premium | premium | MLB | 1998-2010 | 1992-2010 | 2010 | |
| 10 | Chris Nelson | 24 | 3B-2B | R | 17 | 25 | 7 | 7 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 4 | 0 | 1 | 0 | 0 | 1 | 8 | 27 | 1 | 6 | .280 | .308 | .320 | .628 | .120 | .040 | .333 | 3.70 | 14.81 | 4.00 | 0.00 | 2004- 1- 9-COL | premium | premium | premium | MLB | 2010-2014 | 2004-2017 | 2010 | |
| 40 | Brad Eldred | 29 | 1B | R | 11 | 24 | 4 | 6 | 1 | 0 | 1 | 3 | 0 | 0 | 2 | 10 | 1 | 0 | 0 | 0 | 0 | 10 | 27 | 2 | 4 | .250 | .333 | .417 | .750 | .250 | .167 | .385 | 7.41 | 37.04 | 5.00 | 24.00 | 2002- 6- 163-PIT | premium | premium | premium | MLB | 2005-2012 | 1999-2018 | 2010 | |
| 39 | Paul Phillips | 33 | C | R | 12 | 23 | 4 | 5 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 7 | 0 | 0 | 0 | 0 | 0 | 5 | 25 | 0 | 5 | .217 | .280 | .217 | .497 | .087 | .000 | .313 | 8.00 | 28.00 | 3.50 | 0.00 | 1998- 9- 257-KCA | premium | premium | premium | MLB | 2004-2010 | 1998-2012 | 2010 | |
| 26 | Jeff Francis | 29 | P | L | 18 | 22 | 2 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 4 | 6 | 0 | 3 | 1 | 0 | 1 | 2 | 30 | 0 | 2 | .091 | .222 | .091 | .313 | .182 | .000 | .118 | 13.33 | 20.00 | 1.50 | 0.00 | 2002- 1- 9-COL | premium | premium | premium | MLB | 2004-2015 | 2002-2015 | 2010 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 48 | Esmil Rogers | 24 | P | R | 31 | 18 | 2 | 3 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 7 | 0 | 3 | 0 | 0 | 0 | 5 | 21 | 2 | 1 | .167 | .167 | .278 | .445 | .111 | .111 | .273 | 0.00 | 33.33 | 0.00 | 0.00 | 2003- UDFA -COL | premium | premium | premium | MLB | 2009-2015 | 2006-2025 | 2010 | |
| 27 | Greg Smith | 26 | P | L | 10 | 13 | 2 | 4 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 6 | 16 | 2 | 2 | .308 | .308 | .462 | .770 | .154 | .154 | .333 | 0.00 | 6.25 | 0.00 | 0.00 | 2005- 6- 171-ARI | premium | premium | premium | MLB | 2008-2010 | 2003-2016 | 2010 | |
| 8 | Michael McKenry | 25 | C | R | 6 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | .000 | .111 | .000 | .111 | .125 | .000 | .000 | 11.11 | 55.56 | 5.00 | 0.00 | 2006- 7- 198-COL | premium | premium | premium | MLB | 2010-2016 | 2004-2017 | 2010 | |
| 60 | Manny Corpas | 27 | P | R | 51 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | .000 | .286 | .000 | .286 | .400 | .000 | .000 | 28.57 | 42.86 | 1.50 | 0.00 | 1999- UDFA -COL | premium | premium | premium | MLB | 2006-2013 | 2002-2025 | 2010 | |
| 34 | Matt Belisle | 30 | P | R | 73 | 4 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 2 | 0 | 0 | 0 | 2 | 7 | 1 | 0 | .250 | .400 | .500 | .900 | .250 | .250 | .500 | 0.00 | 28.57 | 0.00 | 0.00 | 1998- 2- 52-ATL | premium | premium | premium | MLB | 2003-2018 | 1999-2018 | 2010 | |
| 16 | Huston Street | 26 | P | R | 44 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2004- 1- 40-OAK | premium | premium | premium | MLB | 2005-2017 | 2002-2017 | 2010 | |
| 97 | Joe Beimel | 33 | P | L | 69 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1998- 18- 538-PIT | premium | premium | premium | MLB | 2001-2015 | 1998-2021 | 2010 | |
| 53 | Manny Delcarmen | 28 | P | R | 9 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2000- 2- 62-BOS | premium | premium | premium | MLB | 2005-2010 | 2001-2018 | 2010 | |
| 35 | Taylor Buchholz | 28 | P | R | 7 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1.000 | 1.000 | 1.000 | 2.000 | .000 | .000 | 1.000 | 0.00 | 0.00 | 0.00 | 0.00 | 2000- 6- 175-PHI | premium | premium | premium | MLB | 2006-2011 | 2000-2011 | 2010 | |
| 58 | Juan Rincon | 31 | P | R | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1996- UDFA -MIN | premium | premium | premium | MLB | 2001-2010 | 1997-2014 | 2010 | |
| 51 | Matt Reynolds | 25 | P | L | 21 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | 1.000 | .000 | 1.000 | .000 | .000 | .000 | 100.00 | 0.00 | 0.00 | 0.00 | 2007- 20- 612-COL | premium | premium | premium | MLB | 2010-2016 | 2006-2018 | 2010 | |
| Totals: | 2159 | 5530 | 770 | 1452 | 270 | 54 | 173 | 741 | 99 | 41 | 585 | 1274 | 47 | 56 | 47 | 53 | 103 | 2349 | 6265 | 497 | 955 | .263 | .336 | .425 | .760 | .278 | .162 | .310 | 9.34 | 20.34 | 2.18 | 31.97 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 34 | Matt Belisle | 30 | R | 7 | 5 | 2.93 | 76 | 0 | 0 | 0 | 76 | 11 | 1 | 92.0 | 84 | 34 | 30 | 7 | 16 | 91 | 3 | 1 | 2 | 1.09 | 8.22 | 0.68 | 1.57 | 8.90 | 3.33 | 5.69 | 1998- 2- 52-ATL | premium | premium | premium | MLB | 2003-2018 | 1999-2018 | 2010 |
| 53 | Manny Delcarmen | 28 | R | 0 | 2 | 6.48 | 9 | 0 | 0 | 0 | 9 | 3 | 0 | 8.1 | 12 | 6 | 6 | 1 | 4 | 6 | 1 | 0 | 0 | 1.92 | 12.96 | 1.08 | 4.32 | 6.48 | 6.48 | 1.50 | 2000- 2- 62-BOS | premium | premium | premium | MLB | 2005-2010 | 2001-2018 | 2010 |
| 48 | Esmil Rogers | 24 | R | 2 | 3 | 6.13 | 28 | 8 | 0 | 0 | 20 | 5 | 0 | 72.0 | 94 | 59 | 49 | 5 | 26 | 66 | 5 | 2 | 5 | 1.67 | 11.75 | 0.63 | 3.25 | 8.25 | 7.38 | 2.54 | 2003- UDFA -COL | premium | premium | premium | MLB | 2009-2015 | 2006-2025 | 2010 |
| 60 | Manny Corpas | 27 | R | 3 | 5 | 4.62 | 56 | 0 | 0 | 0 | 56 | 27 | 10 | 62.1 | 66 | 33 | 32 | 7 | 22 | 47 | 1 | 0 | 2 | 1.41 | 9.53 | 1.01 | 3.18 | 6.79 | 4.76 | 2.14 | 1999- UDFA -COL | premium | premium | premium | MLB | 2006-2013 | 2002-2025 | 2010 |
| 63 | Rafael Betancourt | 35 | R | 5 | 1 | 3.61 | 72 | 0 | 0 | 0 | 72 | 18 | 1 | 62.1 | 52 | 25 | 25 | 9 | 8 | 89 | 7 | 0 | 0 | 0.96 | 7.51 | 1.30 | 1.16 | 12.85 | 3.61 | 11.13 | 1993- UDFA -BOS | premium | premium | premium | MLB | 2003-2015 | 1994-2015 | 2010 |
| 44 | Edgmer Escalona | 23 | R | 0 | 0 | 1.50 | 5 | 0 | 0 | 0 | 5 | 2 | 0 | 6.0 | 4 | 1 | 1 | 0 | 4 | 2 | 1 | 0 | 0 | 1.33 | 6.00 | 0.00 | 6.00 | 3.00 | 1.50 | 0.50 | 2004- UDFA -COL | premium | premium | premium | MLB | 2010-2013 | 2007-2022 | 2010 |
| 35 | Octavio Dotel | 36 | R | 0 | 1 | 5.06 | 8 | 0 | 0 | 0 | 8 | 1 | 0 | 5.1 | 6 | 4 | 3 | 1 | 4 | 6 | 3 | 0 | 0 | 1.88 | 10.13 | 1.69 | 6.75 | 10.13 | 6.75 | 1.50 | 1993- UDFA -NYN | premium | premium | premium | MLB | 1999-2013 | 1995-2013 | 2010 |
| 16 | Huston Street | 26 | R | 4 | 4 | 3.61 | 44 | 0 | 0 | 0 | 44 | 39 | 20 | 47.1 | 39 | 21 | 19 | 5 | 11 | 45 | 2 | 1 | 2 | 1.06 | 7.42 | 0.95 | 2.09 | 8.56 | 3.99 | 4.09 | 2004- 1- 40-OAK | premium | premium | premium | MLB | 2005-2017 | 2002-2017 | 2010 |
| 97 | Joe Beimel | 33 | L | 1 | 2 | 3.40 | 71 | 0 | 0 | 0 | 71 | 11 | 0 | 45.0 | 46 | 18 | 17 | 5 | 15 | 21 | 2 | 1 | 0 | 1.36 | 9.20 | 1.00 | 3.00 | 4.20 | 3.60 | 1.40 | 1998- 18- 538-PIT | premium | premium | premium | MLB | 2001-2015 | 1998-2021 | 2010 |
| 27 | Greg Smith | 26 | L | 1 | 2 | 6.23 | 8 | 8 | 0 | 0 | 0 | 0 | 0 | 39.0 | 49 | 28 | 27 | 8 | 24 | 31 | 1 | 0 | 1 | 1.87 | 11.31 | 1.85 | 5.54 | 7.15 | 6.46 | 1.29 | 2005- 6- 171-ARI | premium | premium | premium | MLB | 2008-2010 | 2003-2016 | 2010 |
| 56 | Franklin Morales | 24 | L | 0 | 4 | 6.28 | 35 | 0 | 0 | 0 | 35 | 15 | 3 | 28.2 | 28 | 22 | 20 | 5 | 24 | 27 | 3 | 2 | 3 | 1.81 | 8.79 | 1.57 | 7.53 | 8.48 | 6.91 | 1.13 | 2002- UDFA -COL | premium | premium | premium | MLB | 2007-2016 | 2004-2017 | 2010 |
| 53 | Randy Flores | 34 | L | 2 | 0 | 2.96 | 47 | 0 | 0 | 0 | 47 | 10 | 0 | 27.1 | 22 | 10 | 9 | 4 | 13 | 18 | 0 | 0 | 1 | 1.28 | 7.24 | 1.32 | 4.28 | 5.93 | 3.29 | 1.38 | 1997- 9- 289-NYA | premium | premium | premium | MLB | 2002-2010 | 1994-2011 | 2010 |
| 31 | Matt Daley | 28 | R | 0 | 1 | 4.24 | 28 | 0 | 0 | 0 | 28 | 4 | 0 | 23.1 | 27 | 11 | 11 | 2 | 10 | 18 | 1 | 0 | 3 | 1.59 | 10.41 | 0.77 | 3.86 | 6.94 | 4.24 | 1.80 | 2004- UDFA -COL | premium | premium | premium | MLB | 2009-2014 | 2001-2014 | 2010 |
| 38 | Ubaldo Jimenez | 26 | R | 19 | 8 | 2.88 | 33 | 33 | 4 | 2 | 0 | 0 | 0 | 221.2 | 164 | 73 | 71 | 10 | 92 | 214 | 16 | 1 | 9 | 1.15 | 6.66 | 0.41 | 3.74 | 8.69 | 2.96 | 2.33 | 2001- UDFA -COL | premium | premium | premium | MLB | 2006-2017 | 2002-2017 | 2010 |
| 47 | Samuel Deduno | 26 | R | 0 | 0 | 3.37 | 4 | 0 | 0 | 0 | 4 | 3 | 0 | 2.2 | 3 | 1 | 1 | 1 | 1 | 3 | 0 | 0 | 0 | 1.50 | 10.12 | 3.37 | 3.37 | 10.12 | 3.37 | 3.00 | 2003- UDFA -COL | premium | premium | premium | MLB | 2010-2015 | 2004-2016 | 2010 |
| 58 | Juan Rincon | 31 | R | 0 | 0 | 4.50 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 2.0 | 3 | 1 | 1 | 0 | 2 | 3 | 0 | 0 | 0 | 2.50 | 13.50 | 0.00 | 9.00 | 13.50 | 4.50 | 1.50 | 1996- UDFA -MIN | premium | premium | premium | MLB | 2001-2010 | 1997-2014 | 2010 |
| 51 | Matt Reynolds | 25 | L | 1 | 0 | 2.00 | 21 | 0 | 0 | 0 | 21 | 2 | 0 | 18.0 | 10 | 4 | 4 | 2 | 5 | 17 | 1 | 0 | 2 | 0.83 | 5.00 | 1.00 | 2.50 | 8.50 | 2.00 | 3.40 | 2007- 20- 612-COL | premium | premium | premium | MLB | 2010-2016 | 2006-2018 | 2010 |
| 46 | Jason Hammel | 27 | R | 10 | 9 | 4.81 | 30 | 30 | 0 | 0 | 0 | 0 | 0 | 177.2 | 201 | 97 | 95 | 18 | 47 | 141 | 13 | 2 | 6 | 1.40 | 10.18 | 0.91 | 2.38 | 7.14 | 4.91 | 3.00 | 2002- 10- 284-TBA | premium | premium | premium | MLB | 2006-2018 | 2002-2018 | 2010 |
| 45 | Jhoulys Chacin | 22 | R | 9 | 11 | 3.28 | 28 | 21 | 0 | 0 | 7 | 2 | 0 | 137.1 | 114 | 64 | 50 | 10 | 61 | 138 | 4 | 0 | 9 | 1.27 | 7.47 | 0.66 | 4.00 | 9.04 | 4.19 | 2.26 | 2004- UDFA -COL | premium | premium | premium | MLB | 2009-2022 | 2007-2024 | 2010 |
| 28 | Aaron Cook | 31 | R | 6 | 8 | 5.08 | 23 | 23 | 2 | 0 | 0 | 0 | 0 | 127.2 | 147 | 77 | 72 | 11 | 52 | 62 | 3 | 1 | 4 | 1.56 | 10.36 | 0.78 | 3.67 | 4.37 | 5.43 | 1.19 | 1997- 2- 70-COL | premium | premium | premium | MLB | 2002-2012 | 1997-2013 | 2010 |
| 29 | Jorge De La Rosa | 29 | L | 8 | 7 | 4.22 | 20 | 20 | 0 | 0 | 0 | 0 | 0 | 121.2 | 105 | 62 | 57 | 15 | 55 | 113 | 9 | 1 | 5 | 1.32 | 7.77 | 1.11 | 4.07 | 8.36 | 4.59 | 2.05 | 1998- UDFA -ARI | premium | premium | premium | MLB | 2004-2018 | 1999-2018 | 2010 |
| 26 | Jeff Francis | 29 | L | 4 | 6 | 5.00 | 20 | 19 | 0 | 0 | 1 | 0 | 0 | 104.1 | 119 | 61 | 58 | 11 | 23 | 67 | 1 | 0 | 2 | 1.36 | 10.27 | 0.95 | 1.98 | 5.78 | 5.26 | 2.91 | 2002- 1- 9-COL | premium | premium | premium | MLB | 2004-2015 | 2002-2015 | 2010 |
| 35 | Taylor Buchholz | 28 | R | 1 | 0 | 4.50 | 7 | 0 | 0 | 0 | 7 | 2 | 0 | 10.0 | 10 | 5 | 5 | 2 | 6 | 9 | 0 | 0 | 0 | 1.60 | 9.00 | 1.80 | 5.40 | 8.10 | 4.50 | 1.50 | 2000- 6- 175-PHI | premium | premium | premium | MLB | 2006-2011 | 2000-2011 | 2010 |
| Totals: | 83 | 79 | 4.14 | 675 | 162 | 6 | 2 | 156 | 513 | 35 | 1442.0 | 1405 | 717 | 663 | 139 | 525 | 1234 | 77 | 12 | 56 | 1.34 | 8.77 | 0.87 | 3.28 | 7.70 | 4.48 | 2.35 | premium | premium | premium |