| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 24 | Chris Young | 24 | CF | R | 100 | 160 | 625 | 85 | 155 | 42 | 7 | 22 | 85 | 14 | 5 | 62 | 165 | 1 | 6 | 5 | 2 | 10 | 277 | 699 | 71 | 84 | .248 | .315 | .443 | .758 | .309 | .195 | .300 | 8.87 | 23.61 | 2.66 | 28.41 | 2001- 16- 493-CHA | premium | premium | premium | MLB | 2006-2018 | 2002-2018 | 2008 |
| 6 | Stephen Drew | 25 | SS | L | 108 | 152 | 611 | 91 | 178 | 44 | 11 | 21 | 67 | 3 | 3 | 41 | 109 | 1 | 3 | 7 | 6 | 5 | 307 | 663 | 76 | 102 | .291 | .333 | .502 | .835 | .278 | .211 | .322 | 6.18 | 16.44 | 2.66 | 29.10 | 2004- 1- 15-ARI | premium | premium | premium | MLB | 2006-2017 | 2005-2017 | 2008 |
| 34 | Conor Jackson | 26 | LF-1B | R | 111 | 144 | 540 | 87 | 162 | 31 | 6 | 12 | 75 | 10 | 2 | 59 | 61 | 9 | 1 | 3 | 3 | 14 | 241 | 612 | 49 | 113 | .300 | .376 | .446 | .822 | .270 | .146 | .319 | 9.64 | 9.97 | 1.03 | 45.00 | 2003- 1- 19-ARI | premium | premium | premium | MLB | 2005-2011 | 2001-2013 | 2008 |
| 27 | Mark Reynolds | 24 | 3B | R | 104 | 152 | 539 | 87 | 129 | 28 | 3 | 28 | 97 | 11 | 2 | 64 | 204 | 3 | 1 | 6 | 0 | 10 | 247 | 613 | 59 | 70 | .239 | .320 | .458 | .778 | .354 | .219 | .323 | 10.44 | 33.28 | 3.19 | 19.25 | 2004- 16- 476-ARI | premium | premium | premium | MLB | 2007-2019 | 2002-2019 | 2008 |
| 1 | Orlando Hudson | 30 | 2B | B | 109 | 107 | 407 | 54 | 124 | 29 | 3 | 8 | 41 | 4 | 1 | 40 | 62 | 2 | 3 | 3 | 2 | 18 | 183 | 455 | 40 | 84 | .305 | .367 | .450 | .817 | .251 | .145 | .341 | 8.79 | 13.63 | 1.55 | 50.88 | 1997- 43-1280-TOR | premium | premium | premium | MLB | 2002-2012 | 1998-2012 | 2008 |
| 10 | Justin Upton | 20 | RF | R | 106 | 108 | 356 | 52 | 89 | 19 | 6 | 15 | 42 | 1 | 4 | 54 | 121 | 4 | 0 | 3 | 6 | 3 | 165 | 417 | 40 | 49 | .250 | .353 | .463 | .816 | .357 | .213 | .332 | 12.95 | 29.02 | 2.24 | 23.73 | 2005- 1- 1-ARI | premium | premium | premium | MLB | 2007-2022 | 2006-2022 | 2008 |
| 19 | Chris Snyder | 27 | C | R | 105 | 115 | 334 | 47 | 79 | 22 | 1 | 16 | 64 | 0 | 0 | 56 | 101 | 4 | 5 | 5 | 5 | 7 | 151 | 404 | 39 | 40 | .237 | .348 | .452 | .800 | .383 | .215 | .284 | 13.86 | 25.00 | 1.80 | 20.88 | 2002- 2- 68-ARI | premium | premium | premium | MLB | 2004-2013 | 2000-2014 | 2008 |
| 18 | Chad Tracy | 28 | 1B | L | 95 | 88 | 273 | 25 | 73 | 16 | 0 | 8 | 39 | 0 | 0 | 16 | 49 | 1 | 0 | 2 | 2 | 5 | 113 | 292 | 24 | 49 | .267 | .308 | .414 | .722 | .205 | .147 | .298 | 5.48 | 16.78 | 3.06 | 34.13 | 2001- 7- 218-ARI | premium | premium | premium | MLB | 2004-2013 | 1999-2013 | 2008 |
| 11 | Augie Ojeda | 33 | 2B-3B | B | 90 | 105 | 231 | 27 | 56 | 9 | 2 | 0 | 17 | 0 | 0 | 26 | 24 | 10 | 4 | 1 | 2 | 6 | 69 | 272 | 11 | 45 | .242 | .343 | .299 | .642 | .169 | .057 | .269 | 9.56 | 8.82 | 0.92 | 0.00 | 1996- 13- 381-BAL | premium | premium | premium | MLB | 2000-2010 | 1996-2011 | 2008 |
| 22 | Eric Byrnes | 32 | LF | R | 85 | 52 | 206 | 28 | 43 | 13 | 1 | 6 | 23 | 4 | 4 | 16 | 36 | 2 | 0 | 0 | 0 | 5 | 76 | 224 | 20 | 23 | .209 | .272 | .369 | .641 | .238 | .160 | .226 | 7.14 | 16.07 | 2.25 | 34.33 | 1998- 8- 225-OAK | premium | premium | premium | MLB | 2000-2010 | 1995-2010 | 2008 |
| 26 | Miguel Montero | 24 | C | L | 101 | 70 | 184 | 24 | 47 | 16 | 1 | 5 | 18 | 0 | 0 | 19 | 49 | 2 | 1 | 1 | 3 | 1 | 80 | 207 | 22 | 25 | .255 | .330 | .435 | .765 | .283 | .180 | .321 | 9.18 | 23.67 | 2.58 | 36.80 | 2001- UDFA -ARI | premium | premium | premium | MLB | 2006-2018 | 2002-2018 | 2008 |
| 2 | Chris Burke | 28 | LF-2B | R | 79* | 86 | 165 | 20 | 32 | 5 | 1 | 2 | 12 | 5 | 0 | 27 | 33 | 2 | 2 | 3 | 8 | 2 | 45 | 199 | 8 | 24 | .194 | .310 | .273 | .583 | .273 | .079 | .226 | 13.57 | 16.58 | 1.22 | 82.50 | 2001- 1- 10-HOU | premium | premium | premium | MLB | 2004-2009 | 1999-2010 | 2008 |
| 32 | Adam Dunn | 28 | RF-1B | L | 117 | 44 | 144 | 21 | 35 | 9 | 0 | 8 | 26 | 1 | 0 | 42 | 44 | 1 | 0 | 0 | 7 | 3 | 68 | 187 | 17 | 18 | .243 | .417 | .472 | .889 | .528 | .229 | .293 | 22.46 | 23.53 | 1.05 | 18.00 | 1998- 2- 50-CIN | premium | premium | premium | MLB | 2001-2014 | 1998-2014 | 2008 |
| 28 | Alex Romero | 24 | RF | L | 80* | 78 | 135 | 13 | 31 | 8 | 2 | 1 | 12 | 4 | 0 | 3 | 20 | 1 | 2 | 1 | 0 | 3 | 46 | 142 | 11 | 20 | .230 | .250 | .341 | .591 | .163 | .111 | .261 | 2.11 | 14.08 | 6.67 | 135.00 | 2000- UDFA -MIN | premium | premium | premium | MLB | 2008-2009 | 2002-2018 | 2008 |
| 12 | Jeff Salazar | 27 | LF-RF | L | 91* | 90 | 128 | 17 | 27 | 5 | 3 | 2 | 12 | 0 | 2 | 21 | 41 | 2 | 1 | 0 | 1 | 2 | 44 | 152 | 10 | 17 | .211 | .331 | .344 | .675 | .281 | .133 | .294 | 13.82 | 26.97 | 1.95 | 64.00 | 2002- 8- 231-COL | premium | premium | premium | MLB | 2006-2009 | 2002-2012 | 2008 |
| 15 | Dan Haren | 27 | P | R | 33 | 76 | 8 | 16 | 7 | 0 | 0 | 6 | 0 | 0 | 3 | 15 | 0 | 5 | 1 | 0 | 1 | 23 | 85 | 7 | 9 | .211 | .238 | .303 | .541 | .132 | .092 | .258 | 3.53 | 17.65 | 5.00 | 0.00 | 2001- 2- 72-SLN | premium | premium | premium | MLB | 2003-2015 | 1999-2015 | 2008 | |
| 17 | Brandon Webb | 29 | P | R | 33 | 67 | 2 | 10 | 4 | 0 | 0 | 11 | 0 | 0 | 1 | 30 | 0 | 13 | 0 | 0 | 0 | 14 | 81 | 4 | 6 | .149 | .162 | .209 | .371 | .075 | .060 | .270 | 1.23 | 37.04 | 30.00 | 0.00 | 2000- 8- 249-ARI | premium | premium | premium | MLB | 2003-2009 | 1998-2011 | 2008 | |
| 4 | David Eckstein | 33 | 2B | R | 95 | 18 | 64 | 5 | 14 | 3 | 0 | 1 | 4 | 0 | 0 | 7 | 5 | 1 | 0 | 1 | 0 | 1 | 20 | 73 | 4 | 10 | .219 | .301 | .313 | .614 | .203 | .094 | .220 | 9.59 | 6.85 | 0.71 | 64.00 | 1997- 19- 581-BOS | premium | premium | premium | MLB | 2001-2010 | 1994-2010 | 2008 |
| 13 | Tony Clark | 36 | 1B | B | 95* | 38 | 63 | 7 | 13 | 2 | 0 | 2 | 13 | 0 | 0 | 12 | 23 | 1 | 0 | 1 | 1 | 6 | 21 | 77 | 4 | 9 | .206 | .338 | .333 | .671 | .317 | .127 | .282 | 15.58 | 29.87 | 1.92 | 31.50 | 1990- 1- 2-DET | premium | premium | premium | MLB | 1995-2009 | 1990-2009 | 2008 |
| 44 | Micah Owings | 25 | P | R | 35 | 52 | 7 | 15 | 2 | 0 | 1 | 3 | 0 | 0 | 5 | 21 | 0 | 1 | 0 | 0 | 2 | 20 | 58 | 3 | 12 | .288 | .351 | .385 | .736 | .192 | .097 | .467 | 8.62 | 36.21 | 4.20 | 52.00 | 2005- 3- 83-ARI | premium | premium | premium | MLB | 2007-2012 | 2003-2016 | 2008 | |
| 51 | Randy Johnson | 44 | P | R | 28 | 50 | 2 | 7 | 1 | 0 | 0 | 5 | 0 | 0 | 4 | 26 | 0 | 6 | 0 | 0 | 0 | 8 | 60 | 1 | 6 | .140 | .204 | .160 | .364 | .100 | .020 | .292 | 6.67 | 43.33 | 6.50 | 0.00 | 1985- 2- 36-MON | premium | premium | premium | MLB | 1988-2009 | 1983-2009 | 2008 | |
| 49 | Doug Davis | 32 | P | R | 25 | 42 | 0 | 4 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 13 | 0 | 8 | 0 | 0 | 1 | 4 | 50 | 0 | 4 | .095 | .095 | .095 | .190 | .000 | .000 | .138 | 0.00 | 26.00 | 0.00 | 0.00 | 1996- 10- 293-TEX | premium | premium | premium | MLB | 1999-2011 | 1996-2012 | 2008 | |
| 7 | Robby Hammock | 31 | C | R | 18 | 42 | 4 | 8 | 1 | 0 | 0 | 2 | 0 | 0 | 5 | 9 | 1 | 0 | 0 | 1 | 0 | 9 | 48 | 1 | 7 | .190 | .292 | .214 | .506 | .143 | .024 | .242 | 10.42 | 18.75 | 1.80 | 0.00 | 1998- 23- 703-ARI | premium | premium | premium | MLB | 2003-2011 | 1998-2011 | 2008 | |
| 21 | Jamie D'Antona | 26 | 1B | R | 18 | 17 | 2 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 3 | 19 | 0 | 3 | .176 | .263 | .176 | .439 | .118 | .000 | .231 | 10.53 | 21.05 | 2.00 | 0.00 | 2003- 2- 66-ARI | premium | premium | premium | MLB | 2008-2008 | 2001-2010 | 2008 | |
| 48 | Yusmeiro Petit | 23 | P | R | 19 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | 15 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 46.67 | 0.00 | 0.00 | 2001- UDFA -NYN | premium | premium | premium | MLB | 2006-2021 | 2003-2022 | 2008 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 39 | Max Scherzer | 23 | P | R | 17 | 13 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 15 | 0 | 0 | .000 | .071 | .000 | .071 | .077 | .000 | .000 | 6.67 | 26.67 | 4.00 | 0.00 | 2006- 1- 11-ARI | premium | premium | premium | MLB | 2008-2025 | 2004-2025 | 2008 | |
| 4 | Emilio Bonifacio | 23 | RF-LF | B | 85* | 8 | 12 | 3 | 2 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 3 | 12 | 1 | 1 | .167 | .167 | .250 | .417 | .167 | .083 | .286 | 0.00 | 41.67 | 0.00 | 0.00 | 2001- UDFA -ARI | premium | premium | premium | MLB | 2007-2020 | 2003-2025 | 2008 |
| 31 | Edgar Gonzalez | 25 | P | R | 17 | 10 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 2 | 0 | 0 | 0 | 2 | 12 | 1 | 0 | .100 | .100 | .200 | .300 | .100 | .100 | .143 | 0.00 | 25.00 | 0.00 | 0.00 | 2000- UDFA -ARI | premium | premium | premium | MLB | 2003-2013 | 2002-2023 | 2008 | |
| 29 | Josh Whitesell | 26 | 1B | L | 7 | 7 | 1 | 2 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 5 | 9 | 1 | 1 | .286 | .444 | .714 | 1.158 | .571 | .428 | .250 | 11.11 | 22.22 | 2.00 | 7.00 | 2003- 6- 177-MON | premium | premium | premium | MLB | 2008-2009 | 2001-2014 | 2008 | |
| 50 | Chad Qualls | 29 | P | R | 75 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2000- 2- 67-HOU | premium | premium | premium | MLB | 2004-2017 | 1999-2017 | 2008 | |
| 33 | Billy Buckner | 24 | P | R | 10 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2004- 2- 55-KCA | premium | premium | premium | MLB | 2007-2014 | 2004-2016 | 2008 | |
| 41 | Connor Robertson | 26 | P | R | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2004- 31- 937-OAK | premium | premium | premium | MLB | 2007-2008 | 2003-2010 | 2008 | |
| Totals: | 1956 | 5409 | 720 | 1355 | 318 | 47 | 159 | 683 | 58 | 23 | 587 | 1287 | 49 | 68 | 43 | 49 | 105 | 2244 | 6156 | 524 | 831 | .251 | .327 | .415 | .742 | .279 | .164 | .299 | 9.54 | 20.91 | 2.19 | 34.02 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 36 | Jailen Peguero | 27 | R | 0 | 0 | 4.82 | 7 | 0 | 0 | 0 | 7 | 0 | 0 | 9.1 | 9 | 6 | 5 | 0 | 4 | 5 | 0 | 0 | 1 | 1.39 | 8.68 | 0.00 | 3.86 | 4.82 | 5.79 | 1.25 | 2000- UDFA -HOU | premium | premium | premium | MLB | 2007-2008 | 2002-2021 | 2008 |
| 50 | Chad Qualls | 29 | R | 4 | 8 | 2.81 | 77 | 0 | 0 | 0 | 77 | 21 | 9 | 73.2 | 61 | 29 | 23 | 4 | 18 | 71 | 6 | 0 | 3 | 1.07 | 7.45 | 0.49 | 2.20 | 8.67 | 3.54 | 3.94 | 2000- 2- 67-HOU | premium | premium | premium | MLB | 2004-2017 | 1999-2017 | 2008 |
| 56 | Tony Pena | 26 | R | 3 | 2 | 4.33 | 72 | 0 | 0 | 0 | 72 | 20 | 3 | 72.2 | 80 | 38 | 35 | 5 | 17 | 52 | 4 | 0 | 3 | 1.33 | 9.91 | 0.62 | 2.11 | 6.44 | 4.71 | 3.06 | 2002- UDFA -ARI | premium | premium | premium | MLB | 2006-2011 | 2004-2016 | 2008 |
| 41 | Connor Robertson | 26 | R | 0 | 1 | 5.14 | 6 | 0 | 0 | 0 | 6 | 3 | 0 | 7.0 | 8 | 4 | 4 | 1 | 2 | 2 | 0 | 0 | 1 | 1.43 | 10.29 | 1.29 | 2.57 | 2.57 | 5.14 | 1.00 | 2004- 31- 937-OAK | premium | premium | premium | MLB | 2007-2008 | 2003-2010 | 2008 |
| 38 | Brandon Lyon | 28 | R | 3 | 5 | 4.70 | 61 | 0 | 0 | 0 | 61 | 50 | 26 | 59.1 | 75 | 34 | 31 | 7 | 13 | 44 | 1 | 0 | 0 | 1.48 | 11.38 | 1.06 | 1.97 | 6.67 | 5.16 | 3.38 | 1999- 14- 433-TOR | premium | premium | premium | MLB | 2001-2013 | 2000-2014 | 2008 |
| 48 | Yusmeiro Petit | 23 | R | 3 | 5 | 4.31 | 19 | 8 | 0 | 0 | 11 | 6 | 0 | 56.1 | 45 | 29 | 27 | 12 | 14 | 42 | 3 | 1 | 1 | 1.05 | 7.19 | 1.92 | 2.24 | 6.71 | 4.63 | 3.00 | 2001- UDFA -NYN | premium | premium | premium | MLB | 2006-2021 | 2003-2022 | 2008 |
| 39 | Max Scherzer | 23 | R | 0 | 4 | 3.05 | 16 | 7 | 0 | 0 | 9 | 2 | 0 | 56.0 | 48 | 24 | 19 | 5 | 21 | 66 | 2 | 0 | 5 | 1.23 | 7.71 | 0.80 | 3.38 | 10.61 | 3.86 | 3.14 | 2006- 1- 11-ARI | premium | premium | premium | MLB | 2008-2025 | 2004-2025 | 2008 |
| 37 | Juan Cruz | 29 | R | 4 | 0 | 2.61 | 57 | 0 | 0 | 0 | 57 | 10 | 0 | 51.2 | 34 | 17 | 15 | 5 | 31 | 71 | 1 | 0 | 3 | 1.26 | 5.92 | 0.87 | 5.40 | 12.37 | 2.96 | 2.29 | 1997- UDFA -CHN | premium | premium | premium | MLB | 2001-2012 | 1998-2012 | 2008 |
| 31 | Edgar Gonzalez | 25 | R | 1 | 3 | 6.00 | 17 | 6 | 0 | 0 | 11 | 3 | 0 | 48.0 | 58 | 34 | 32 | 8 | 21 | 32 | 4 | 0 | 3 | 1.65 | 10.88 | 1.50 | 3.94 | 6.00 | 6.38 | 1.52 | 2000- UDFA -ARI | premium | premium | premium | MLB | 2003-2013 | 2002-2023 | 2008 |
| 46 | Wilfredo Ledezma | 27 | L | 0 | 0 | 0.00 | 3 | 0 | 0 | 0 | 3 | 2 | 0 | 4.0 | 2 | 0 | 0 | 0 | 3 | 4 | 0 | 0 | 0 | 1.25 | 4.50 | 0.00 | 6.75 | 9.00 | 0.00 | 1.33 | 1998- UDFA -BOS | premium | premium | premium | MLB | 2003-2011 | 1999-2021 | 2008 |
| 45 | Doug Slaten | 28 | L | 0 | 3 | 4.73 | 45 | 0 | 0 | 0 | 45 | 13 | 0 | 32.1 | 33 | 20 | 17 | 4 | 14 | 20 | 0 | 0 | 4 | 1.45 | 9.19 | 1.11 | 3.90 | 5.57 | 5.57 | 1.43 | 2000- 17- 519-ARI | premium | premium | premium | MLB | 2006-2012 | 2000-2012 | 2008 |
| 47 | Leo Rosales | 27 | R | 1 | 1 | 4.20 | 27 | 0 | 0 | 0 | 27 | 6 | 0 | 30.0 | 32 | 15 | 14 | 2 | 15 | 18 | 2 | 0 | 1 | 1.57 | 9.60 | 0.60 | 4.50 | 5.40 | 4.50 | 1.20 | 2003- 20- 581-SDN | premium | premium | premium | MLB | 2008-2010 | 2002-2017 | 2008 |
| 57 | Jon Rauch | 29 | R | 0 | 6 | 6.56 | 26 | 0 | 0 | 0 | 26 | 10 | 1 | 23.1 | 27 | 18 | 17 | 6 | 9 | 22 | 1 | 0 | 0 | 1.54 | 10.41 | 2.31 | 3.47 | 8.49 | 6.94 | 2.44 | 1999- 3- 99-CHA | premium | premium | premium | MLB | 2002-2013 | 1997-2013 | 2008 |
| 17 | Brandon Webb | 29 | R | 22 | 7 | 3.30 | 34 | 34 | 3 | 1 | 0 | 0 | 0 | 226.2 | 206 | 95 | 83 | 13 | 65 | 183 | 8 | 1 | 12 | 1.20 | 8.18 | 0.52 | 2.58 | 7.27 | 3.77 | 2.82 | 2000- 8- 249-ARI | premium | premium | premium | MLB | 2003-2009 | 1998-2011 | 2008 |
| 15 | Dan Haren | 27 | R | 16 | 8 | 3.33 | 33 | 33 | 1 | 1 | 0 | 0 | 0 | 216.0 | 204 | 86 | 80 | 19 | 40 | 206 | 11 | 0 | 6 | 1.13 | 8.50 | 0.79 | 1.67 | 8.58 | 3.58 | 5.15 | 2001- 2- 72-SLN | premium | premium | premium | MLB | 2003-2015 | 1999-2015 | 2008 |
| 52 | Brandon Medders | 28 | R | 1 | 0 | 4.58 | 18 | 0 | 0 | 0 | 18 | 3 | 0 | 19.2 | 17 | 11 | 10 | 2 | 11 | 8 | 1 | 0 | 2 | 1.42 | 7.78 | 0.92 | 5.03 | 3.66 | 5.03 | 0.73 | 2001- 8- 248-ARI | premium | premium | premium | MLB | 2005-2010 | 2000-2010 | 2008 |
| 51 | Randy Johnson | 44 | L | 11 | 10 | 3.91 | 30 | 30 | 2 | 0 | 0 | 0 | 0 | 184.0 | 184 | 92 | 80 | 24 | 44 | 173 | 2 | 1 | 6 | 1.24 | 9.00 | 1.17 | 2.15 | 8.46 | 4.50 | 3.93 | 1985- 2- 36-MON | premium | premium | premium | MLB | 1988-2009 | 1983-2009 | 2008 |
| 49 | Doug Davis | 32 | L | 6 | 8 | 4.32 | 26 | 26 | 0 | 0 | 0 | 0 | 0 | 146.0 | 160 | 76 | 70 | 13 | 64 | 112 | 7 | 0 | 4 | 1.53 | 9.86 | 0.80 | 3.95 | 6.90 | 4.68 | 1.75 | 1996- 10- 293-TEX | premium | premium | premium | MLB | 1999-2011 | 1996-2012 | 2008 |
| 33 | Billy Buckner | 24 | R | 1 | 0 | 3.21 | 10 | 0 | 0 | 0 | 10 | 5 | 0 | 14.0 | 16 | 5 | 5 | 3 | 4 | 11 | 2 | 0 | 1 | 1.43 | 10.29 | 1.93 | 2.57 | 7.07 | 3.21 | 2.75 | 2004- 2- 55-KCA | premium | premium | premium | MLB | 2007-2014 | 2004-2016 | 2008 |
| 44 | Micah Owings | 25 | R | 6 | 9 | 5.93 | 22 | 18 | 0 | 0 | 4 | 2 | 0 | 104.2 | 104 | 73 | 69 | 14 | 41 | 87 | 4 | 0 | 12 | 1.39 | 8.94 | 1.20 | 3.53 | 7.48 | 6.28 | 2.12 | 2005- 3- 83-ARI | premium | premium | premium | MLB | 2007-2012 | 2003-2016 | 2008 |
| Totals: | 82 | 80 | 3.99 | 606 | 162 | 6 | 2 | 156 | 444 | 39 | 1434.2 | 1403 | 706 | 636 | 147 | 451 | 1229 | 59 | 3 | 68 | 1.29 | 8.80 | 0.92 | 2.83 | 7.71 | 4.43 | 2.73 | premium | premium | premium |