| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 10 | Miguel Tejada | 34 | SS | R | 96 | 158 | 632 | 92 | 179 | 38 | 3 | 13 | 66 | 7 | 7 | 24 | 72 | 6 | 1 | 3 | 4 | 32 | 262 | 666 | 54 | 125 | .283 | .314 | .415 | .729 | .169 | .132 | .302 | 3.60 | 10.81 | 3.00 | 48.62 | 1993- UDFA -OAK | premium | premium | premium | MLB | 1997-2013 | 1995-2015 | 2008 |
| 9 | Hunter Pence | 25 | RF | R | 102 | 157 | 595 | 78 | 160 | 34 | 4 | 25 | 83 | 11 | 10 | 40 | 124 | 4 | 0 | 3 | 2 | 14 | 277 | 642 | 63 | 97 | .269 | .318 | .466 | .784 | .266 | .197 | .301 | 6.23 | 19.31 | 3.10 | 23.80 | 2004- 2- 64-HOU | premium | premium | premium | MLB | 2007-2020 | 2003-2020 | 2008 |
| 17 | Lance Berkman | 32 | 1B | B | 128 | 159 | 554 | 114 | 173 | 46 | 4 | 29 | 106 | 18 | 4 | 99 | 108 | 7 | 0 | 5 | 18 | 13 | 314 | 665 | 79 | 94 | .312 | .420 | .567 | .987 | .458 | .255 | .341 | 14.89 | 16.24 | 1.09 | 19.10 | 1997- 1- 16-HOU | premium | premium | premium | MLB | 1999-2013 | 1995-2013 | 2008 |
| 14 | Michael Bourn | 25 | CF | L | 83 | 138 | 467 | 57 | 107 | 10 | 4 | 5 | 29 | 41 | 10 | 37 | 111 | 2 | 7 | 1 | 0 | 3 | 140 | 514 | 19 | 88 | .229 | .288 | .300 | .588 | .216 | .071 | .290 | 7.20 | 21.60 | 3.00 | 93.40 | 2003- 4- 115-PHI | premium | premium | premium | MLB | 2006-2016 | 2001-2017 | 2008 |
| 45 | Carlos Lee | 32 | LF | R | 121 | 115 | 436 | 61 | 137 | 27 | 0 | 28 | 100 | 4 | 1 | 37 | 49 | 3 | 0 | 5 | 7 | 8 | 248 | 481 | 55 | 82 | .314 | .368 | .569 | .937 | .346 | .255 | .299 | 7.69 | 10.19 | 1.32 | 15.57 | 1994- UDFA -CHA | premium | premium | premium | MLB | 1999-2012 | 1994-2012 | 2008 |
| 21 | Ty Wigginton | 30 | 3B | R | 114 | 111 | 386 | 50 | 110 | 22 | 1 | 23 | 58 | 4 | 6 | 32 | 69 | 8 | 0 | 3 | 1 | 9 | 203 | 429 | 46 | 64 | .285 | .350 | .526 | .876 | .319 | .241 | .293 | 7.46 | 16.08 | 2.16 | 16.78 | 1998- 17- 514-NYN | premium | premium | premium | MLB | 2002-2013 | 1996-2013 | 2008 |
| 3 | Kazuo Matsui | 32 | 2B | B | 106 | 96 | 375 | 58 | 110 | 26 | 3 | 6 | 33 | 20 | 5 | 37 | 53 | 0 | 7 | 3 | 0 | 3 | 160 | 422 | 35 | 75 | .293 | .354 | .427 | .781 | .272 | .134 | .326 | 8.77 | 12.56 | 1.43 | 62.50 | 2003- UDFA -NYN | premium | premium | premium | MLB | 2004-2010 | 1995-2018 | 2008 |
| 27 | Geoff Blum | 35 | 3B | B | 92 | 114 | 325 | 36 | 78 | 14 | 1 | 14 | 53 | 1 | 2 | 21 | 54 | 3 | 0 | 7 | 2 | 5 | 136 | 356 | 29 | 49 | .240 | .287 | .418 | .705 | .240 | .178 | .242 | 5.90 | 15.17 | 2.57 | 23.21 | 1994- 7- 196-MON | premium | premium | premium | MLB | 1999-2012 | 1992-2012 | 2008 |
| 2 | Darin Erstad | 34 | LF-CF | L | 89 | 140 | 322 | 49 | 89 | 16 | 0 | 4 | 31 | 2 | 3 | 14 | 68 | 2 | 2 | 2 | 3 | 3 | 117 | 342 | 20 | 69 | .276 | .309 | .363 | .672 | .127 | .087 | .337 | 4.09 | 19.88 | 4.86 | 80.50 | 1995- 1- 1-CAL | premium | premium | premium | MLB | 1996-2009 | 1995-2009 | 2008 |
| 8 | Mark Loretta | 36 | 2B | R | 99 | 101 | 261 | 27 | 73 | 15 | 0 | 4 | 38 | 0 | 0 | 29 | 30 | 2 | 0 | 5 | 1 | 9 | 100 | 297 | 19 | 54 | .280 | .350 | .383 | .733 | .215 | .103 | .297 | 9.76 | 10.10 | 1.03 | 65.25 | 1993- 7- 207-MIL | premium | premium | premium | MLB | 1995-2009 | 1993-2009 | 2008 |
| 11 | Brad Ausmus | 39 | C | R | 81 | 81 | 216 | 15 | 47 | 8 | 0 | 3 | 24 | 0 | 2 | 25 | 41 | 2 | 6 | 1 | 3 | 4 | 64 | 250 | 11 | 36 | .218 | .303 | .296 | .599 | .185 | .078 | .254 | 10.00 | 16.40 | 1.64 | 72.00 | 1987- 48-1152-NYA | premium | premium | premium | MLB | 1993-2010 | 1988-2010 | 2008 |
| 55 | Humberto Quintero | 28 | C | R | 78* | 59 | 168 | 16 | 38 | 6 | 0 | 2 | 12 | 0 | 0 | 6 | 34 | 4 | 5 | 0 | 0 | 5 | 50 | 183 | 8 | 30 | .226 | .270 | .298 | .568 | .107 | .072 | .273 | 3.28 | 18.58 | 5.67 | 84.00 | 1997- UDFA -CHA | premium | premium | premium | MLB | 2003-2014 | 1999-2016 | 2008 |
| 46 | J.R. Towles | 24 | C | R | 71* | 54 | 146 | 10 | 20 | 5 | 0 | 4 | 16 | 0 | 0 | 16 | 40 | 6 | 3 | 0 | 1 | 3 | 37 | 171 | 9 | 11 | .137 | .250 | .253 | .503 | .226 | .116 | .157 | 9.36 | 23.39 | 2.50 | 36.50 | 2004- 20- 604-HOU | premium | premium | premium | MLB | 2007-2011 | 2004-2014 | 2008 |
| 31 | David Newhan | 34 | 2B | L | 93* | 64 | 104 | 11 | 27 | 5 | 2 | 2 | 12 | 1 | 0 | 6 | 28 | 0 | 0 | 1 | 0 | 3 | 42 | 111 | 9 | 18 | .260 | .297 | .404 | .701 | .212 | .144 | .333 | 5.41 | 25.23 | 4.67 | 52.00 | 1995- 17- 456-OAK | premium | premium | premium | MLB | 1999-2008 | 1995-2009 | 2008 |
| 44 | Roy Oswalt | 30 | P | R | 30 | 70 | 3 | 15 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 18 | 0 | 5 | 0 | 0 | 0 | 15 | 75 | 0 | 15 | .214 | .214 | .214 | .428 | .000 | .000 | .288 | 0.00 | 24.00 | 0.00 | 0.00 | 1996- 23- 684-HOU | premium | premium | premium | MLB | 2001-2013 | 1997-2013 | 2008 | |
| 50 | Reggie Abercrombie | 26 | LF-CF | R | 34 | 55 | 10 | 17 | 5 | 0 | 2 | 5 | 5 | 2 | 1 | 23 | 2 | 1 | 1 | 0 | 0 | 28 | 60 | 7 | 10 | .309 | .339 | .509 | .848 | .273 | .200 | .484 | 1.67 | 38.33 | 23.00 | 27.50 | 1999- 23- 704-LAN | premium | premium | premium | MLB | 2006-2008 | 2000-2019 | 2008 | |
| 22 | Jose Cruz | 34 | LF-CF | B | 38 | 49 | 6 | 6 | 1 | 0 | 0 | 1 | 0 | 0 | 11 | 9 | 0 | 0 | 0 | 0 | 0 | 7 | 60 | 1 | 5 | .122 | .283 | .143 | .426 | .245 | .021 | .150 | 18.33 | 15.00 | 0.82 | 0.00 | 1995- 1- 3-SEA | premium | premium | premium | MLB | 1997-2008 | 1993-2008 | 2008 | |
| 41 | Brandon Backe | 30 | P | R | 29 | 47 | 8 | 13 | 2 | 0 | 2 | 3 | 0 | 0 | 3 | 18 | 1 | 5 | 0 | 0 | 0 | 21 | 56 | 4 | 9 | .277 | .333 | .447 | .780 | .234 | .170 | .407 | 5.36 | 32.14 | 6.00 | 23.50 | 1998- 18- 552-TBA | premium | premium | premium | MLB | 2002-2009 | 1998-2009 | 2008 | |
| 38 | Brian Moehler | 36 | P | R | 30 | 44 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 4 | 27 | 0 | 2 | 0 | 0 | 0 | 2 | 50 | 1 | 0 | .023 | .104 | .045 | .149 | .114 | .022 | .059 | 8.00 | 54.00 | 6.75 | 0.00 | 1993- 6- 165-DET | premium | premium | premium | MLB | 1996-2010 | 1993-2010 | 2008 | |
| 51 | Wandy Rodriguez | 29 | P | B | 24 | 41 | 3 | 5 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 11 | 0 | 4 | 0 | 0 | 1 | 6 | 45 | 1 | 4 | .122 | .122 | .146 | .268 | .024 | .024 | .167 | 0.00 | 24.44 | 0.00 | 0.00 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2005-2015 | 2001-2015 | 2008 | |
| 13 | Jose Castillo | 27 | 3B | R | 89 | 15 | 32 | 4 | 9 | 1 | 0 | 0 | 2 | 0 | 0 | 2 | 10 | 0 | 0 | 1 | 0 | 0 | 10 | 35 | 1 | 8 | .281 | .314 | .313 | .627 | .094 | .032 | .391 | 5.71 | 28.57 | 5.00 | 0.00 | 1997- UDFA -PIT | premium | premium | premium | MLB | 2004-2008 | 1999-2016 | 2008 |
| 30 | Shawn Chacon | 30 | P | R | 13 | 24 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 10 | 0 | 2 | 0 | 0 | 0 | 3 | 28 | 0 | 3 | .125 | .192 | .125 | .317 | .083 | .000 | .214 | 7.14 | 35.71 | 5.00 | 0.00 | 1996- 3- 86-COL | premium | premium | premium | MLB | 2001-2008 | 1996-2009 | 2008 | |
| 39 | Randy Wolf | 31 | P | L | 12 | 23 | 1 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 13 | 0 | 2 | 0 | 0 | 0 | 3 | 26 | 0 | 3 | .130 | .167 | .130 | .297 | .043 | .000 | .300 | 3.85 | 50.00 | 13.00 | 0.00 | 1997- 2- 54-PHI | premium | premium | premium | MLB | 1999-2015 | 1997-2015 | 2008 | |
| 43 | Chris Sampson | 30 | P | R | 52 | 22 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 9 | 0 | 3 | 0 | 0 | 0 | 3 | 26 | 0 | 3 | .136 | .174 | .136 | .310 | .045 | .000 | .231 | 3.85 | 34.62 | 9.00 | 0.00 | 1999- 8- 263-HOU | premium | premium | premium | MLB | 2006-2010 | 1999-2011 | 2008 | |
| 19 | Mark Saccomanno | 28 | 1B | R | 10 | 10 | 1 | 2 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 6 | 10 | 2 | 0 | .200 | .200 | .600 | .800 | .400 | .400 | .167 | 0.00 | 30.00 | 0.00 | 10.00 | 2003- 23- 689-HOU | premium | premium | premium | MLB | 2008-2008 | 1999-2010 | 2008 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 13 | Tomas Perez | 34 | 2B | B | 8 | 10 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 10 | 0 | 2 | .200 | .200 | .200 | .400 | .000 | .000 | .250 | 0.00 | 20.00 | 0.00 | 0.00 | 1998- 45-1333-MON | premium | premium | premium | MLB | 1995-2008 | 1993-2008 | 2008 | |
| 20 | Jack Cassel | 27 | P | R | 9 | 9 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 2 | 9 | 0 | 2 | .222 | .222 | .222 | .444 | .000 | .000 | .400 | 0.00 | 44.44 | 0.00 | 0.00 | 2000- 25- 739-SDN | premium | premium | premium | MLB | 2007-2008 | 1999-2009 | 2008 | |
| 23 | Edwin Maysonet | 26 | SS-2B | R | 7 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 7 | 0 | 1 | .143 | .143 | .143 | .286 | .000 | .000 | .200 | 0.00 | 28.57 | 0.00 | 0.00 | 2003- 19- 569-HOU | premium | premium | premium | MLB | 2008-2012 | 2003-2014 | 2008 | |
| 48 | Tim Byrdak | 34 | P | L | 56 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 6 | 0 | 1 | .167 | .167 | .167 | .334 | .000 | .000 | .250 | 0.00 | 33.33 | 0.00 | 0.00 | 1994- 5- 135-KCA | premium | premium | premium | MLB | 1998-2013 | 1994-2013 | 2008 | |
| 50 | Runelvys Hernandez | 30 | P | R | 4 | 4 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 6 | 0 | 1 | .250 | .400 | .250 | .650 | .250 | .000 | .500 | 16.67 | 33.33 | 2.00 | 0.00 | 1998- UDFA -KCA | premium | premium | premium | MLB | 2002-2008 | 2001-2010 | 2008 | |
| 59 | J.R. House | 28 | C | R | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 1999- 5- 152-PIT | premium | premium | premium | MLB | 2003-2008 | 1999-2011 | 2008 | |
| 54 | Chad Paronto | 32 | P | R | 6 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1996- 8- 231-BAL | premium | premium | premium | MLB | 2001-2009 | 1994-2011 | 2008 | |
| 1 | Alberto Arias | 24 | P | R | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2000- UDFA -COL | premium | premium | premium | MLB | 2007-2009 | 2003-2009 | 2008 | |
| 29 | Geoff Geary | 31 | P | R | 53 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1998- 15- 434-PHI | premium | premium | premium | MLB | 2003-2009 | 1997-2011 | 2008 | |
| 56 | Oscar Villarreal | 26 | P | L | 33 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1998- UDFA -ARI | premium | premium | premium | MLB | 2003-2008 | 1999-2017 | 2008 | |
| 64 | Fernando Nieve | 25 | P | R | 10 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2006-2010 | 2001-2018 | 2008 | |
| 47 | Jose Valverde | 30 | P | R | 69 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1997- UDFA -ARI | premium | premium | premium | MLB | 2003-2014 | 1999-2019 | 2008 | |
| 26 | Doug Brocail | 41 | P | L | 65 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1986- 1- 12-SDN | premium | premium | premium | MLB | 1992-2009 | 1986-2009 | 2008 | |
| Totals: | 2160 | 5451 | 712 | 1432 | 284 | 22 | 167 | 684 | 114 | 52 | 449 | 1051 | 52 | 57 | 41 | 42 | 116 | 2261 | 6050 | 473 | 959 | .263 | .323 | .415 | .737 | .246 | .152 | .296 | 7.42 | 17.37 | 2.34 | 32.64 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 30 | Shawn Chacon | 30 | R | 2 | 3 | 5.04 | 15 | 15 | 0 | 0 | 0 | 0 | 0 | 85.2 | 88 | 52 | 48 | 16 | 41 | 53 | 2 | 0 | 2 | 1.51 | 9.25 | 1.68 | 4.31 | 5.57 | 5.46 | 1.29 | 1996- 3- 86-COL | premium | premium | premium | MLB | 2001-2008 | 1996-2009 | 2008 |
| 1 | Alberto Arias | 24 | R | 1 | 1 | 6.75 | 3 | 2 | 0 | 0 | 1 | 0 | 0 | 8.0 | 11 | 6 | 6 | 0 | 6 | 8 | 0 | 0 | 1 | 2.13 | 12.38 | 0.00 | 6.75 | 9.00 | 6.75 | 1.33 | 2000- UDFA -COL | premium | premium | premium | MLB | 2007-2009 | 2003-2009 | 2008 |
| 47 | Jose Valverde | 30 | R | 6 | 3 | 3.38 | 74 | 0 | 0 | 0 | 74 | 71 | 44 | 72.0 | 62 | 28 | 27 | 10 | 23 | 83 | 3 | 2 | 2 | 1.18 | 7.75 | 1.25 | 2.88 | 10.38 | 3.50 | 3.61 | 1997- UDFA -ARI | premium | premium | premium | MLB | 2003-2014 | 1999-2019 | 2008 |
| 39 | Randy Wolf | 31 | L | 6 | 2 | 3.57 | 12 | 12 | 1 | 1 | 0 | 0 | 0 | 70.2 | 68 | 31 | 28 | 7 | 24 | 57 | 1 | 0 | 4 | 1.30 | 8.66 | 0.89 | 3.06 | 7.26 | 3.95 | 2.38 | 1997- 2- 54-PHI | premium | premium | premium | MLB | 1999-2015 | 1997-2015 | 2008 |
| 26 | Doug Brocail | 41 | R | 7 | 5 | 3.93 | 72 | 0 | 0 | 0 | 72 | 21 | 2 | 68.2 | 63 | 30 | 30 | 8 | 21 | 64 | 1 | 1 | 3 | 1.22 | 8.26 | 1.05 | 2.75 | 8.39 | 3.93 | 3.05 | 1986- 1- 12-SDN | premium | premium | premium | MLB | 1992-2009 | 1986-2009 | 2008 |
| 29 | Geoff Geary | 31 | R | 2 | 3 | 2.53 | 55 | 0 | 0 | 0 | 55 | 8 | 0 | 64.0 | 45 | 18 | 18 | 3 | 28 | 45 | 0 | 1 | 2 | 1.14 | 6.33 | 0.42 | 3.94 | 6.33 | 2.53 | 1.61 | 1998- 15- 434-PHI | premium | premium | premium | MLB | 2003-2009 | 1997-2011 | 2008 |
| 53 | Wesley Wright | 23 | L | 4 | 3 | 5.01 | 71 | 0 | 0 | 0 | 71 | 15 | 1 | 55.2 | 45 | 34 | 31 | 8 | 34 | 57 | 2 | 1 | 4 | 1.42 | 7.28 | 1.29 | 5.50 | 9.22 | 5.50 | 1.68 | 2003- 7- 211-LAN | premium | premium | premium | MLB | 2008-2015 | 2003-2017 | 2008 |
| 48 | Tim Byrdak | 34 | L | 2 | 1 | 3.90 | 59 | 0 | 0 | 0 | 59 | 9 | 0 | 55.1 | 45 | 24 | 24 | 10 | 29 | 47 | 0 | 0 | 2 | 1.34 | 7.32 | 1.63 | 4.72 | 7.64 | 3.90 | 1.62 | 1994- 5- 135-KCA | premium | premium | premium | MLB | 1998-2013 | 1994-2013 | 2008 |
| 56 | Oscar Villarreal | 26 | R | 1 | 3 | 5.02 | 35 | 0 | 0 | 0 | 35 | 13 | 0 | 37.2 | 42 | 25 | 21 | 12 | 17 | 21 | 2 | 0 | 2 | 1.57 | 10.04 | 2.87 | 4.06 | 5.02 | 5.97 | 1.24 | 1998- UDFA -ARI | premium | premium | premium | MLB | 2003-2008 | 1999-2017 | 2008 |
| 58 | Dave Borkowski | 31 | R | 0 | 2 | 7.50 | 26 | 0 | 0 | 0 | 26 | 5 | 0 | 36.0 | 54 | 30 | 30 | 9 | 14 | 24 | 0 | 0 | 1 | 1.89 | 13.50 | 2.25 | 3.50 | 6.00 | 7.50 | 1.71 | 1995- 11- 294-DET | premium | premium | premium | MLB | 1999-2008 | 1995-2009 | 2008 |
| 20 | Jack Cassel | 27 | R | 1 | 1 | 5.64 | 9 | 3 | 0 | 0 | 6 | 1 | 0 | 30.1 | 38 | 21 | 19 | 5 | 8 | 14 | 2 | 1 | 1 | 1.52 | 11.27 | 1.48 | 2.37 | 4.15 | 6.23 | 1.75 | 2000- 25- 739-SDN | premium | premium | premium | MLB | 2007-2008 | 1999-2009 | 2008 |
| 22 | LaTroy Hawkins | 35 | R | 2 | 0 | 0.43 | 24 | 0 | 0 | 0 | 24 | 4 | 1 | 21.0 | 11 | 3 | 1 | 0 | 5 | 25 | 1 | 0 | 0 | 0.76 | 4.71 | 0.00 | 2.14 | 10.71 | 1.29 | 5.00 | 1991- 7- 180-MIN | premium | premium | premium | MLB | 1995-2015 | 1991-2015 | 2008 |
| 44 | Roy Oswalt | 30 | R | 17 | 10 | 3.54 | 32 | 32 | 3 | 2 | 0 | 0 | 0 | 208.2 | 199 | 89 | 82 | 23 | 47 | 165 | 1 | 0 | 10 | 1.18 | 8.58 | 0.99 | 2.03 | 7.12 | 3.84 | 3.51 | 1996- 23- 684-HOU | premium | premium | premium | MLB | 2001-2013 | 1997-2013 | 2008 |
| 50 | Runelvys Hernandez | 30 | R | 0 | 3 | 8.38 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 19.1 | 32 | 19 | 18 | 4 | 11 | 15 | 0 | 0 | 0 | 2.22 | 14.90 | 1.86 | 5.12 | 6.98 | 8.84 | 1.36 | 1998- UDFA -KCA | premium | premium | premium | MLB | 2002-2008 | 2001-2010 | 2008 |
| 41 | Brandon Backe | 30 | R | 9 | 14 | 6.05 | 31 | 31 | 0 | 0 | 0 | 0 | 0 | 166.2 | 202 | 114 | 112 | 36 | 77 | 127 | 2 | 0 | 4 | 1.67 | 10.91 | 1.94 | 4.16 | 6.86 | 6.16 | 1.65 | 1998- 18- 552-TBA | premium | premium | premium | MLB | 2002-2009 | 1998-2009 | 2008 |
| 38 | Brian Moehler | 36 | R | 11 | 8 | 4.56 | 31 | 26 | 0 | 0 | 5 | 0 | 0 | 150.0 | 166 | 79 | 76 | 20 | 36 | 82 | 3 | 0 | 4 | 1.35 | 9.96 | 1.20 | 2.16 | 4.92 | 4.74 | 2.28 | 1993- 6- 165-DET | premium | premium | premium | MLB | 1996-2010 | 1993-2010 | 2008 |
| 51 | Wandy Rodriguez | 29 | L | 9 | 7 | 3.54 | 25 | 25 | 0 | 0 | 0 | 0 | 0 | 137.1 | 136 | 65 | 54 | 14 | 44 | 131 | 2 | 3 | 5 | 1.31 | 8.91 | 0.92 | 2.88 | 8.58 | 4.26 | 2.98 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2005-2015 | 2001-2015 | 2008 |
| 43 | Chris Sampson | 30 | R | 6 | 4 | 4.22 | 54 | 11 | 0 | 0 | 43 | 6 | 0 | 117.1 | 118 | 60 | 55 | 8 | 23 | 61 | 0 | 0 | 3 | 1.20 | 9.05 | 0.61 | 1.76 | 4.68 | 4.60 | 2.65 | 1999- 8- 263-HOU | premium | premium | premium | MLB | 2006-2010 | 1999-2011 | 2008 |
| 64 | Fernando Nieve | 25 | R | 0 | 1 | 8.44 | 11 | 0 | 0 | 0 | 11 | 1 | 0 | 10.2 | 17 | 10 | 10 | 2 | 2 | 12 | 0 | 0 | 0 | 1.78 | 14.34 | 1.69 | 1.69 | 10.12 | 8.44 | 6.00 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2006-2010 | 2001-2018 | 2008 |
| 54 | Chad Paronto | 32 | R | 0 | 1 | 4.35 | 6 | 0 | 0 | 0 | 6 | 3 | 0 | 10.1 | 11 | 5 | 5 | 2 | 2 | 4 | 0 | 0 | 0 | 1.26 | 9.58 | 1.74 | 1.74 | 3.48 | 4.35 | 2.00 | 1996- 8- 231-BAL | premium | premium | premium | MLB | 2001-2009 | 1994-2011 | 2008 |
| Totals: | 86 | 75 | 4.39 | 649 | 161 | 4 | 3 | 157 | 488 | 48 | 1425.1 | 1453 | 743 | 695 | 197 | 492 | 1095 | 22 | 9 | 50 | 1.36 | 9.17 | 1.24 | 3.11 | 6.91 | 4.69 | 2.23 | premium | premium | premium |