| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 9 | Juan Pierre | 28 | CF | L | 96 | 162 | 699 | 87 | 204 | 32 | 13 | 3 | 40 | 58 | 20 | 32 | 38 | 8 | 10 | 1 | 0 | 6 | 271 | 750 | 48 | 156 | .292 | .330 | .388 | .718 | .196 | .096 | .305 | 4.27 | 5.07 | 1.19 | 233.00 | 1998- 13- 390-COL | premium | premium | premium | MLB | 2000-2013 | 1998-2013 | 2006 |
| 16 | Aramis Ramirez | 28 | 3B | R | 116 | 157 | 594 | 93 | 173 | 38 | 4 | 38 | 119 | 2 | 1 | 50 | 63 | 9 | 0 | 7 | 4 | 15 | 333 | 660 | 80 | 93 | .291 | .352 | .561 | .913 | .355 | .270 | .270 | 7.58 | 9.55 | 1.26 | 15.63 | 1994- UDFA -PIT | premium | premium | premium | MLB | 1998-2015 | 1996-2015 | 2006 |
| 5 | Ronny Cedeno | 23 | SS | R | 78 | 151 | 534 | 51 | 131 | 18 | 7 | 6 | 41 | 8 | 8 | 17 | 109 | 3 | 15 | 3 | 4 | 10 | 181 | 572 | 31 | 100 | .245 | .271 | .339 | .610 | .125 | .094 | .296 | 2.97 | 19.06 | 6.41 | 89.00 | 1999- UDFA -CHN | premium | premium | premium | MLB | 2005-2014 | 2001-2015 | 2006 |
| 11 | Jacque Jones | 31 | RF | L | 107 | 149 | 533 | 73 | 152 | 31 | 1 | 27 | 81 | 9 | 1 | 35 | 116 | 5 | 2 | 2 | 6 | 17 | 266 | 577 | 59 | 93 | .285 | .334 | .499 | .833 | .295 | .214 | .319 | 6.07 | 20.10 | 3.31 | 19.74 | 1996- 2- 37-MIN | premium | premium | premium | MLB | 1999-2008 | 1994-2010 | 2006 |
| 19 | Matt Murton | 24 | LF | R | 106 | 144 | 455 | 70 | 135 | 22 | 3 | 13 | 62 | 5 | 2 | 45 | 62 | 5 | 1 | 2 | 1 | 16 | 202 | 508 | 38 | 97 | .297 | .365 | .444 | .809 | .253 | .147 | .319 | 8.86 | 12.20 | 1.38 | 35.00 | 2003- 1- 32-BOS | premium | premium | premium | MLB | 2005-2009 | 2001-2017 | 2006 |
| 8 | Michael Barrett | 29 | C | R | 114 | 107 | 375 | 54 | 115 | 25 | 3 | 16 | 53 | 0 | 1 | 33 | 41 | 5 | 2 | 3 | 2 | 12 | 194 | 418 | 44 | 71 | .307 | .368 | .517 | .885 | .296 | .210 | .308 | 7.89 | 9.81 | 1.24 | 23.44 | 1995- 1- 28-MON | premium | premium | premium | MLB | 1998-2009 | 1995-2010 | 2006 |
| 7 | Todd Walker | 33 | 2B-1B | L | 99 | 94 | 318 | 38 | 88 | 16 | 1 | 6 | 40 | 0 | 1 | 38 | 27 | 1 | 1 | 4 | 1 | 7 | 124 | 362 | 23 | 65 | .277 | .352 | .390 | .742 | .230 | .113 | .284 | 10.50 | 7.46 | 0.71 | 53.00 | 1994- 1- 8-MIN | premium | premium | premium | MLB | 1996-2007 | 1992-2007 | 2006 |
| 24 | Henry Blanco | 34 | C | R | 93 | 74 | 241 | 23 | 64 | 15 | 2 | 6 | 37 | 0 | 0 | 14 | 38 | 0 | 4 | 2 | 1 | 8 | 101 | 261 | 23 | 41 | .266 | .304 | .419 | .723 | .212 | .153 | .291 | 5.36 | 14.56 | 2.71 | 40.17 | 1989- UDFA -LAN | premium | premium | premium | MLB | 1997-2013 | 1990-2013 | 2006 |
| 13 | Neifi Perez | 33 | 2B | B | 74 | 87 | 236 | 27 | 60 | 13 | 1 | 2 | 24 | 0 | 1 | 5 | 21 | 0 | 2 | 3 | 2 | 3 | 81 | 246 | 16 | 44 | .254 | .266 | .343 | .609 | .106 | .089 | .269 | 2.03 | 8.54 | 4.20 | 118.00 | 1992- UDFA -COL | premium | premium | premium | MLB | 1996-2007 | 1993-2007 | 2006 |
| 17 | John Mabry | 35 | 1B | L | 81 | 107 | 210 | 16 | 43 | 8 | 1 | 5 | 25 | 0 | 0 | 23 | 57 | 1 | 0 | 3 | 0 | 5 | 68 | 237 | 14 | 29 | .205 | .283 | .324 | .607 | .229 | .119 | .252 | 9.70 | 24.05 | 2.48 | 42.00 | 1991- 6- 155-SLN | premium | premium | premium | MLB | 1994-2007 | 1991-2007 | 2006 |
| 40 | Phil Nevin | 35 | 1B | R | 100 | 67 | 179 | 26 | 49 | 4 | 0 | 12 | 33 | 0 | 0 | 17 | 52 | 0 | 0 | 0 | 0 | 4 | 89 | 196 | 16 | 33 | .274 | .337 | .497 | .834 | .318 | .223 | .322 | 8.67 | 26.53 | 3.06 | 14.92 | 1992- 1- 1-HOU | premium | premium | premium | MLB | 1995-2006 | 1990-2006 | 2006 |
| 25 | Derrek Lee | 30 | 1B | R | 109* | 50 | 175 | 30 | 50 | 9 | 0 | 8 | 30 | 8 | 4 | 25 | 41 | 0 | 0 | 4 | 1 | 11 | 83 | 204 | 17 | 33 | .286 | .368 | .474 | .842 | .354 | .188 | .323 | 12.25 | 20.10 | 1.64 | 21.88 | 1993- 1- 14-SDN | premium | premium | premium | MLB | 1997-2011 | 1993-2011 | 2006 |
| 29 | Angel Pagan | 24 | LF-RF | B | 92* | 77 | 170 | 28 | 42 | 6 | 2 | 5 | 18 | 4 | 2 | 15 | 28 | 0 | 1 | 1 | 0 | 3 | 67 | 187 | 13 | 29 | .247 | .306 | .394 | .700 | .247 | .147 | .268 | 8.02 | 14.97 | 1.87 | 34.00 | 1999- 4- 136-NYN | premium | premium | premium | MLB | 2006-2016 | 2000-2016 | 2006 |
| 4 | Freddie Bynum | 26 | 2B-LF | L | 99* | 71 | 136 | 20 | 35 | 5 | 5 | 4 | 12 | 8 | 4 | 9 | 44 | 1 | 2 | 0 | 0 | 2 | 62 | 148 | 14 | 21 | .257 | .308 | .456 | .764 | .294 | .199 | .352 | 6.08 | 29.73 | 4.89 | 34.00 | 2000- 2- 60-OAK | premium | premium | premium | MLB | 2005-2008 | 2000-2012 | 2006 |
| 7 | Ryan Theriot | 26 | 2B | R | 125* | 53 | 134 | 34 | 44 | 11 | 3 | 3 | 16 | 13 | 2 | 17 | 18 | 2 | 6 | 0 | 0 | 5 | 70 | 159 | 17 | 27 | .328 | .412 | .522 | .934 | .403 | .194 | .363 | 10.69 | 11.32 | 1.06 | 44.67 | 2001- 3- 78-CHN | premium | premium | premium | MLB | 2005-2012 | 1999-2012 | 2006 |
| 15 | Jerry Hairston | 30 | 2B | R | 71* | 38 | 82 | 8 | 17 | 3 | 0 | 0 | 4 | 3 | 0 | 4 | 14 | 1 | 5 | 0 | 2 | 1 | 20 | 92 | 3 | 14 | .207 | .253 | .244 | .497 | .122 | .037 | .250 | 4.35 | 15.22 | 3.50 | 0.00 | 1997- 11- 345-BAL | premium | premium | premium | MLB | 1998-2013 | 1996-2013 | 2006 |
| 38 | Carlos Zambrano | 25 | P | B | 35 | 73 | 9 | 11 | 0 | 0 | 6 | 11 | 1 | 0 | 1 | 27 | 0 | 5 | 1 | 0 | 2 | 29 | 80 | 6 | 5 | .151 | .160 | .397 | .557 | .274 | .246 | .122 | 1.25 | 33.75 | 27.00 | 12.17 | 1997- UDFA -CHN | premium | premium | premium | MLB | 2001-2012 | 1998-2019 | 2006 | |
| 3 | Cesar Izturis | 26 | SS | B | 78* | 22 | 73 | 4 | 17 | 2 | 0 | 0 | 6 | 0 | 1 | 5 | 8 | 0 | 1 | 0 | 0 | 3 | 19 | 79 | 2 | 15 | .233 | .282 | .260 | .542 | .082 | .027 | .262 | 6.33 | 10.13 | 1.60 | 0.00 | 1996- UDFA -TOR | premium | premium | premium | MLB | 2001-2013 | 1997-2013 | 2006 |
| 1 | Tony Womack | 36 | 2B | L | 19 | 50 | 6 | 14 | 1 | 0 | 1 | 2 | 1 | 1 | 4 | 4 | 0 | 3 | 0 | 1 | 0 | 18 | 57 | 2 | 12 | .280 | .333 | .360 | .693 | .160 | .080 | .289 | 7.02 | 7.02 | 1.00 | 50.00 | 1991- 7- 201-PIT | premium | premium | premium | MLB | 1993-2006 | 1991-2006 | 2006 | |
| 31 | Greg Maddux | 40 | P | R | 20 | 43 | 2 | 4 | 1 | 0 | 0 | 4 | 1 | 0 | 2 | 17 | 0 | 3 | 0 | 0 | 0 | 5 | 48 | 1 | 3 | .093 | .133 | .116 | .249 | .093 | .023 | .154 | 4.17 | 35.42 | 8.50 | 0.00 | 1984- 2- 31-CHN | premium | premium | premium | MLB | 1986-2008 | 1984-2008 | 2006 | |
| 45 | Sean Marshall | 23 | P | L | 22 | 40 | 3 | 5 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 19 | 0 | 3 | 0 | 0 | 0 | 8 | 43 | 1 | 4 | .125 | .125 | .200 | .325 | .075 | .075 | .200 | 0.00 | 44.19 | 0.00 | 40.00 | 2003- 6- 163-CHN | premium | premium | premium | MLB | 2006-2014 | 2001-2014 | 2006 | |
| 15 | Scott Moore | 22 | 1B-3B | L | 16 | 38 | 6 | 10 | 2 | 0 | 2 | 5 | 0 | 0 | 2 | 10 | 1 | 1 | 0 | 0 | 1 | 18 | 42 | 4 | 6 | .263 | .317 | .474 | .791 | .263 | .211 | .308 | 4.76 | 23.81 | 5.00 | 19.00 | 2002- 1- 8-DET | premium | premium | premium | MLB | 2006-2012 | 2002-2015 | 2006 | |
| 53 | Rich Hill | 26 | P | L | 16 | 30 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 11 | 0 | 3 | 0 | 0 | 0 | 4 | 34 | 1 | 2 | .100 | .129 | .133 | .262 | .067 | .033 | .158 | 2.94 | 32.35 | 11.00 | 0.00 | 2002- 4- 112-CHN | premium | premium | premium | MLB | 2005-2025 | 2000-2025 | 2006 | |
| 58 | Geovany Soto | 23 | C | R | 11 | 25 | 1 | 5 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 6 | 26 | 1 | 4 | .200 | .231 | .240 | .471 | .040 | .040 | .250 | 0.00 | 19.23 | 0.00 | 0.00 | 2001- 11- 318-CHN | premium | premium | premium | MLB | 2005-2017 | 2001-2017 | 2006 | |
| 49 | Carlos Marmol | 23 | P | R | 20 | 23 | 3 | 6 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 7 | 0 | 1 | 0 | 0 | 1 | 10 | 24 | 2 | 4 | .261 | .261 | .435 | .696 | .174 | .174 | .333 | 0.00 | 29.17 | 0.00 | 23.00 | 1999- UDFA -CHN | premium | premium | premium | MLB | 2006-2014 | 2001-2015 | 2006 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 30 | Buck Coats | 24 | CF | L | 18 | 18 | 2 | 3 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 1 | 7 | 18 | 2 | 1 | .167 | .167 | .389 | .556 | .222 | .222 | .182 | 0.00 | 33.33 | 0.00 | 18.00 | 2000- 18- 523-CHN | premium | premium | premium | MLB | 2006-2008 | 2000-2011 | 2006 | |
| 33 | Glendon Rusch | 31 | P | L | 24 | 15 | 1 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 3 | 0 | 0 | 0 | 4 | 18 | 1 | 2 | .200 | .200 | .267 | .467 | .067 | .067 | .273 | 0.00 | 22.22 | 0.00 | 0.00 | 1993- 17- 469-KCA | premium | premium | premium | MLB | 1997-2009 | 1993-2009 | 2006 | |
| 22 | Mark Prior | 25 | P | R | 8 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 14 | 0 | 1 | .077 | .077 | .077 | .154 | .000 | .000 | .125 | 0.00 | 35.71 | 0.00 | 0.00 | 2001- 1- 2-CHN | premium | premium | premium | MLB | 2002-2006 | 1999-2013 | 2006 | |
| 51 | Juan Mateo | 23 | P | R | 12 | 12 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 0 | 2 | 0 | 0 | 0 | 0 | 14 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 64.29 | 0.00 | 0.00 | 2001- UDFA -CHN | premium | premium | premium | MLB | 2006-2006 | 2003-2011 | 2006 | |
| 37 | Angel Guzman | 24 | P | R | 15 | 12 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 4 | 0 | 4 | 0 | 0 | 1 | 3 | 16 | 1 | 1 | .167 | .167 | .250 | .417 | .083 | .083 | .250 | 0.00 | 25.00 | 0.00 | 0.00 | 1999- UDFA -CHN | premium | premium | premium | MLB | 2006-2009 | 2001-2012 | 2006 | |
| 28 | Michael Restovich | 27 | RF-LF | R | 10 | 12 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 3 | 13 | 1 | 1 | .167 | .231 | .250 | .481 | .167 | .083 | .286 | 7.69 | 38.46 | 5.00 | 0.00 | 1997- 2- 61-MIN | premium | premium | premium | MLB | 2002-2007 | 1998-2011 | 2006 | |
| 52 | Wade Miller | 29 | P | R | 5 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 7 | 0 | 1 | .143 | .143 | .143 | .286 | .000 | .000 | .500 | 0.00 | 71.43 | 0.00 | 0.00 | 1996- 20- 594-HOU | premium | premium | premium | MLB | 1999-2007 | 1996-2009 | 2006 | |
| 34 | Kerry Wood | 29 | P | R | 4 | 6 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 6 | 1 | 2 | .500 | .500 | .667 | 1.167 | .167 | .167 | .500 | 0.00 | 0.00 | 0.00 | 0.00 | 1995- 1- 4-CHN | premium | premium | premium | MLB | 1998-2012 | 1995-2012 | 2006 | |
| 44 | Roberto Novoa | 26 | P | R | 64 | 5 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 2 | 5 | 1 | 0 | .200 | .200 | .400 | .600 | .200 | .200 | .333 | 0.00 | 40.00 | 0.00 | 0.00 | 1999- UDFA -PIT | premium | premium | premium | MLB | 2004-2006 | 2001-2014 | 2006 | |
| 61 | Jose Reyes | 22 | C | B | 4 | 5 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 2 | 0 | 0 | 0 | 1 | 7 | 0 | 1 | .200 | .200 | .200 | .400 | .000 | .000 | .500 | 0.00 | 42.86 | 0.00 | 0.00 | 1999- UDFA -CHN | premium | premium | premium | MLB | 2006-2006 | 2002-2007 | 2006 | |
| 48 | Ryan O'Malley | 26 | P | R | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 75.00 | 0.00 | 0.00 | 2002- UDFA -CHN | premium | premium | premium | MLB | 2006-2006 | 2001-2008 | 2006 | |
| 54 | David Aardsma | 24 | P | R | 43 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2003- 1- 22-SFN | premium | premium | premium | MLB | 2004-2015 | 2001-2017 | 2006 | |
| 32,57 | Jerome Williams | 24 | P | R | 5 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 1999- 1- 39-SFN | premium | premium | premium | MLB | 2003-2016 | 1999-2018 | 2006 | |
| 55 | Les Walrond | 29 | P | L | 10 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 1998- 13- 378-SLN | premium | premium | premium | MLB | 2003-2008 | 1996-2012 | 2006 | |
| 46 | Ryan Dempster | 29 | P | R | 70 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1995- 3- 66-TEX | premium | premium | premium | MLB | 1998-2013 | 1995-2013 | 2006 | |
| 62 | Bob Howry | 32 | P | L | 81 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1.000 | 1.000 | 1.000 | 2.000 | .000 | .000 | 1.000 | 0.00 | 0.00 | 0.00 | 0.00 | 1994- 5- 144-SFN | premium | premium | premium | MLB | 1998-2010 | 1994-2010 | 2006 | |
| 47 | Scott Eyre | 34 | P | L | 70 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1991- 9- 248-TEX | premium | premium | premium | MLB | 1997-2009 | 1992-2009 | 2006 | |
| 20 | Jae Kuk Ryu | 23 | P | R | 10 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2001- UDFA -CHN | premium | premium | premium | MLB | 2006-2008 | 2001-2008 | 2006 | |
| 50,13 | Will Ohman | 28 | P | L | 74 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1.000 | 1.000 | 1.000 | 2.000 | .000 | .000 | 1.000 | 0.00 | 0.00 | 0.00 | 0.00 | 1998- 8- 226-CHN | premium | premium | premium | MLB | 2000-2012 | 1998-2012 | 2006 | |
| 43 | Michael Wuertz | 27 | P | R | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1997- 11- 334-CHN | premium | premium | premium | MLB | 2004-2011 | 1998-2014 | 2006 | |
| Totals: | 2299 | 5587 | 716 | 1496 | 271 | 46 | 166 | 677 | 121 | 49 | 395 | 928 | 43 | 86 | 36 | 25 | 135 | 2357 | 6147 | 483 | 1013 | .268 | .319 | .422 | .741 | .238 | .154 | .294 | 6.43 | 15.10 | 2.35 | 33.66 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 53 | Rich Hill | 26 | L | 6 | 7 | 4.17 | 17 | 16 | 2 | 1 | 1 | 0 | 0 | 99.1 | 83 | 51 | 46 | 16 | 39 | 90 | 3 | 0 | 2 | 1.23 | 7.52 | 1.45 | 3.53 | 8.15 | 4.62 | 2.31 | 2002- 4- 112-CHN | premium | premium | premium | MLB | 2005-2025 | 2000-2025 | 2006 |
| 49 | Carlos Marmol | 23 | R | 5 | 7 | 6.08 | 19 | 13 | 0 | 0 | 6 | 1 | 0 | 77.0 | 71 | 54 | 52 | 14 | 59 | 59 | 3 | 1 | 0 | 1.69 | 8.30 | 1.64 | 6.90 | 6.90 | 6.31 | 1.00 | 1999- UDFA -CHN | premium | premium | premium | MLB | 2006-2014 | 2001-2015 | 2006 |
| 62 | Bob Howry | 32 | R | 4 | 5 | 3.17 | 84 | 0 | 0 | 0 | 84 | 26 | 5 | 76.2 | 70 | 28 | 27 | 8 | 17 | 71 | 1 | 0 | 3 | 1.13 | 8.22 | 0.94 | 2.00 | 8.33 | 3.29 | 4.18 | 1994- 5- 144-SFN | premium | premium | premium | MLB | 1998-2010 | 1994-2010 | 2006 |
| 44 | Roberto Novoa | 26 | R | 2 | 1 | 4.26 | 66 | 0 | 0 | 0 | 66 | 10 | 0 | 76.0 | 77 | 47 | 36 | 15 | 32 | 53 | 4 | 0 | 0 | 1.43 | 9.12 | 1.78 | 3.79 | 6.28 | 5.57 | 1.66 | 1999- UDFA -PIT | premium | premium | premium | MLB | 2004-2006 | 2001-2014 | 2006 |
| 46 | Ryan Dempster | 29 | R | 1 | 9 | 4.80 | 74 | 0 | 0 | 0 | 74 | 64 | 24 | 75.0 | 77 | 47 | 40 | 5 | 36 | 67 | 6 | 0 | 3 | 1.51 | 9.24 | 0.60 | 4.32 | 8.04 | 5.64 | 1.86 | 1995- 3- 66-TEX | premium | premium | premium | MLB | 1998-2013 | 1995-2013 | 2006 |
| 33 | Glendon Rusch | 31 | L | 3 | 8 | 7.46 | 25 | 9 | 0 | 0 | 16 | 5 | 0 | 66.1 | 86 | 57 | 55 | 21 | 33 | 59 | 0 | 0 | 0 | 1.79 | 11.67 | 2.85 | 4.48 | 8.01 | 7.73 | 1.79 | 1993- 17- 469-KCA | premium | premium | premium | MLB | 1997-2009 | 1993-2009 | 2006 |
| 50,13 | Will Ohman | 28 | L | 1 | 1 | 4.13 | 78 | 0 | 0 | 0 | 78 | 14 | 0 | 65.1 | 51 | 30 | 30 | 6 | 34 | 74 | 4 | 0 | 0 | 1.30 | 7.03 | 0.83 | 4.68 | 10.19 | 4.13 | 2.18 | 1998- 8- 226-CHN | premium | premium | premium | MLB | 2000-2012 | 1998-2012 | 2006 |
| 47 | Scott Eyre | 34 | L | 1 | 3 | 3.38 | 74 | 0 | 0 | 0 | 74 | 15 | 0 | 61.1 | 61 | 25 | 23 | 11 | 30 | 73 | 6 | 0 | 0 | 1.48 | 8.95 | 1.61 | 4.40 | 10.71 | 3.67 | 2.43 | 1991- 9- 248-TEX | premium | premium | premium | MLB | 1997-2009 | 1992-2009 | 2006 |
| 37 | Angel Guzman | 24 | R | 0 | 6 | 7.39 | 15 | 10 | 0 | 0 | 5 | 1 | 0 | 56.0 | 68 | 48 | 46 | 9 | 37 | 60 | 8 | 1 | 6 | 1.88 | 10.93 | 1.45 | 5.95 | 9.64 | 7.71 | 1.62 | 1999- UDFA -CHN | premium | premium | premium | MLB | 2006-2009 | 2001-2012 | 2006 |
| 54 | David Aardsma | 24 | R | 3 | 0 | 4.08 | 45 | 0 | 0 | 0 | 45 | 9 | 0 | 53.0 | 41 | 25 | 24 | 9 | 28 | 49 | 1 | 0 | 1 | 1.30 | 6.96 | 1.53 | 4.75 | 8.32 | 4.25 | 1.75 | 2003- 1- 22-SFN | premium | premium | premium | MLB | 2004-2015 | 2001-2017 | 2006 |
| 51 | Juan Mateo | 23 | R | 1 | 3 | 5.32 | 11 | 10 | 0 | 0 | 1 | 0 | 0 | 45.2 | 51 | 31 | 27 | 6 | 23 | 35 | 1 | 0 | 0 | 1.62 | 10.05 | 1.18 | 4.53 | 6.90 | 6.11 | 1.52 | 2001- UDFA -CHN | premium | premium | premium | MLB | 2006-2006 | 2003-2011 | 2006 |
| 22 | Mark Prior | 25 | R | 1 | 6 | 7.21 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 43.2 | 46 | 39 | 35 | 9 | 28 | 38 | 4 | 0 | 0 | 1.69 | 9.48 | 1.85 | 5.77 | 7.83 | 8.04 | 1.36 | 2001- 1- 2-CHN | premium | premium | premium | MLB | 2002-2006 | 1999-2013 | 2006 |
| 43 | Michael Wuertz | 27 | R | 3 | 1 | 2.66 | 41 | 0 | 0 | 0 | 41 | 4 | 0 | 40.2 | 35 | 14 | 12 | 5 | 16 | 42 | 1 | 0 | 0 | 1.25 | 7.75 | 1.11 | 3.54 | 9.30 | 3.10 | 2.63 | 1997- 11- 334-CHN | premium | premium | premium | MLB | 2004-2011 | 1998-2014 | 2006 |
| 48 | Scott Williamson | 30 | R | 2 | 3 | 5.08 | 31 | 0 | 0 | 0 | 31 | 5 | 0 | 28.1 | 27 | 17 | 16 | 2 | 16 | 32 | 7 | 1 | 0 | 1.52 | 8.58 | 0.64 | 5.08 | 10.16 | 5.40 | 2.00 | 1997- 9- 278-CIN | premium | premium | premium | MLB | 1999-2007 | 1995-2011 | 2006 |
| 38 | Carlos Zambrano | 25 | R | 16 | 7 | 3.41 | 33 | 33 | 0 | 0 | 0 | 0 | 0 | 214.0 | 162 | 91 | 81 | 20 | 115 | 210 | 9 | 1 | 0 | 1.29 | 6.81 | 0.84 | 4.84 | 8.83 | 3.83 | 1.83 | 1997- UDFA -CHN | premium | premium | premium | MLB | 2001-2012 | 1998-2019 | 2006 |
| 52 | Wade Miller | 29 | R | 0 | 2 | 4.57 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 21.2 | 19 | 12 | 11 | 4 | 18 | 20 | 1 | 0 | 0 | 1.71 | 7.89 | 1.66 | 7.48 | 8.31 | 4.98 | 1.11 | 1996- 20- 594-HOU | premium | premium | premium | MLB | 1999-2007 | 1996-2009 | 2006 |
| 34 | Kerry Wood | 29 | R | 1 | 2 | 4.12 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 19.2 | 19 | 13 | 9 | 5 | 8 | 13 | 1 | 0 | 0 | 1.37 | 8.69 | 2.29 | 3.66 | 5.95 | 5.95 | 1.63 | 1995- 1- 4-CHN | premium | premium | premium | MLB | 1998-2012 | 1995-2012 | 2006 |
| 55 | Les Walrond | 29 | L | 0 | 1 | 6.23 | 10 | 2 | 0 | 0 | 8 | 0 | 0 | 17.1 | 19 | 13 | 12 | 2 | 12 | 21 | 0 | 0 | 0 | 1.79 | 9.87 | 1.04 | 6.23 | 10.90 | 6.75 | 1.75 | 1998- 13- 378-SLN | premium | premium | premium | MLB | 2003-2008 | 1996-2012 | 2006 |
| 20 | Jae Kuk Ryu | 23 | R | 0 | 1 | 8.40 | 10 | 1 | 0 | 0 | 9 | 4 | 0 | 15.0 | 23 | 14 | 14 | 7 | 6 | 17 | 1 | 0 | 0 | 1.93 | 13.80 | 4.20 | 3.60 | 10.20 | 8.40 | 2.83 | 2001- UDFA -CHN | premium | premium | premium | MLB | 2006-2008 | 2001-2008 | 2006 |
| 31 | Greg Maddux | 40 | R | 9 | 11 | 4.69 | 22 | 22 | 0 | 0 | 0 | 0 | 0 | 136.1 | 153 | 78 | 71 | 14 | 23 | 81 | 0 | 0 | 0 | 1.29 | 10.10 | 0.92 | 1.52 | 5.35 | 5.15 | 3.52 | 1984- 2- 31-CHN | premium | premium | premium | MLB | 1986-2008 | 1984-2008 | 2006 |
| 45 | Sean Marshall | 23 | L | 6 | 9 | 5.59 | 24 | 24 | 0 | 0 | 0 | 0 | 0 | 125.2 | 132 | 85 | 78 | 20 | 59 | 77 | 6 | 0 | 0 | 1.52 | 9.45 | 1.43 | 4.23 | 5.51 | 6.09 | 1.31 | 2003- 6- 163-CHN | premium | premium | premium | MLB | 2006-2014 | 2001-2014 | 2006 |
| 48 | Ryan O'Malley | 26 | L | 1 | 1 | 2.13 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 12.2 | 10 | 3 | 3 | 0 | 7 | 4 | 0 | 0 | 0 | 1.34 | 7.11 | 0.00 | 4.97 | 2.84 | 2.13 | 0.57 | 2002- UDFA -CHN | premium | premium | premium | MLB | 2006-2006 | 2001-2008 | 2006 |
| 32,57 | Jerome Williams | 24 | R | 0 | 2 | 7.30 | 5 | 2 | 0 | 0 | 3 | 1 | 0 | 12.1 | 15 | 12 | 10 | 2 | 11 | 5 | 0 | 0 | 0 | 2.11 | 10.95 | 1.46 | 8.03 | 3.65 | 8.76 | 0.45 | 1999- 1- 39-SFN | premium | premium | premium | MLB | 2003-2016 | 1999-2018 | 2006 |
| Totals: | 66 | 96 | 4.74 | 704 | 162 | 2 | 1 | 159 | 542 | 29 | 1439.0 | 1396 | 834 | 758 | 210 | 687 | 1250 | 67 | 4 | 15 | 1.45 | 8.73 | 1.31 | 4.30 | 7.82 | 5.22 | 1.82 | premium | premium | premium |