| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 12 | Freddy Sanchez | 28 | 3B | R | 109 | 157 | 582 | 85 | 200 | 53 | 2 | 6 | 85 | 3 | 2 | 31 | 52 | 7 | 3 | 9 | 6 | 12 | 275 | 632 | 61 | 139 | .344 | .378 | .473 | .851 | .184 | .129 | .364 | 4.91 | 8.23 | 1.68 | 97.00 | 2000- 11- 332-BOS | premium | premium | premium | MLB | 2002-2011 | 2000-2012 | 2006 |
| 38 | Jason Bay | 27 | LF | R | 119 | 159 | 570 | 101 | 163 | 29 | 3 | 35 | 109 | 11 | 2 | 102 | 156 | 8 | 0 | 9 | 9 | 15 | 303 | 689 | 67 | 96 | .286 | .396 | .532 | .928 | .440 | .246 | .330 | 14.80 | 22.64 | 1.53 | 16.29 | 2000- 22- 645-MON | premium | premium | premium | MLB | 2003-2013 | 1999-2013 | 2006 |
| 2 | Jack Wilson | 28 | SS | R | 90 | 142 | 543 | 70 | 148 | 27 | 1 | 8 | 35 | 4 | 3 | 33 | 65 | 4 | 9 | 5 | 0 | 15 | 201 | 594 | 36 | 112 | .273 | .316 | .370 | .686 | .160 | .097 | .295 | 5.56 | 10.94 | 1.97 | 67.88 | 1998- 9- 258-SLN | premium | premium | premium | MLB | 2001-2012 | 1998-2012 | 2006 |
| 14 | Jose Castillo | 25 | 2B | R | 88 | 148 | 518 | 54 | 131 | 25 | 0 | 14 | 65 | 6 | 4 | 32 | 98 | 5 | 1 | 6 | 8 | 22 | 198 | 562 | 39 | 92 | .253 | .299 | .382 | .681 | .195 | .129 | .284 | 5.69 | 17.44 | 3.06 | 37.00 | 1997- UDFA -PIT | premium | premium | premium | MLB | 2004-2008 | 1999-2016 | 2006 |
| 26 | Ronny Paulino | 25 | C | R | 99 | 129 | 442 | 37 | 137 | 19 | 0 | 6 | 55 | 0 | 0 | 34 | 79 | 2 | 1 | 2 | 5 | 17 | 174 | 481 | 25 | 112 | .310 | .360 | .394 | .754 | .161 | .084 | .365 | 7.07 | 16.42 | 2.32 | 73.67 | 1997- UDFA -PIT | premium | premium | premium | MLB | 2005-2012 | 1999-2016 | 2006 |
| 19 | Jose Bautista | 25 | CF-3B | R | 98 | 117 | 400 | 58 | 94 | 20 | 3 | 16 | 51 | 2 | 4 | 46 | 110 | 16 | 3 | 4 | 2 | 12 | 168 | 469 | 39 | 55 | .235 | .335 | .420 | .755 | .295 | .185 | .281 | 9.81 | 23.45 | 2.39 | 25.00 | 2000- 20- 599-PIT | premium | premium | premium | MLB | 2004-2018 | 2001-2018 | 2006 |
| 6 | Chris Duffy | 26 | CF | L | 92 | 84 | 314 | 46 | 80 | 14 | 3 | 2 | 18 | 26 | 1 | 19 | 71 | 10 | 4 | 1 | 1 | 1 | 106 | 348 | 19 | 61 | .255 | .317 | .338 | .655 | .223 | .083 | .322 | 5.46 | 20.40 | 3.74 | 157.00 | 2001- 8- 234-PIT | premium | premium | premium | MLB | 2005-2009 | 2001-2010 | 2006 |
| 3 | Jeromy Burnitz | 37 | RF | L | 91 | 111 | 313 | 35 | 72 | 12 | 0 | 16 | 49 | 1 | 1 | 22 | 74 | 5 | 0 | 2 | 4 | 8 | 132 | 342 | 28 | 44 | .230 | .289 | .422 | .711 | .262 | .192 | .249 | 6.43 | 21.64 | 3.36 | 19.56 | 1990- 1- 17-NYN | premium | premium | premium | MLB | 1993-2006 | 1988-2006 | 2006 |
| 49 | Nate McLouth | 24 | CF-RF | L | 91 | 106 | 270 | 50 | 63 | 16 | 2 | 7 | 16 | 10 | 1 | 18 | 59 | 5 | 3 | 1 | 0 | 7 | 104 | 297 | 25 | 38 | .233 | .293 | .385 | .678 | .252 | .152 | .273 | 6.06 | 19.87 | 3.28 | 38.57 | 2000- 25- 749-PIT | premium | premium | premium | MLB | 2005-2014 | 2001-2014 | 2006 |
| 36 | Craig Wilson | 29 | 1B-RF | R | 99 | 85 | 255 | 38 | 68 | 11 | 2 | 13 | 41 | 1 | 0 | 24 | 88 | 5 | 0 | 2 | 2 | 6 | 122 | 286 | 26 | 42 | .267 | .339 | .478 | .817 | .310 | .211 | .353 | 8.39 | 30.77 | 3.67 | 19.62 | 1995- 2- 47-TOR | premium | premium | premium | MLB | 2001-2007 | 1995-2008 | 2006 |
| 25 | Sean Casey | 31 | 1B | L | 93 | 59 | 213 | 30 | 63 | 15 | 0 | 3 | 29 | 0 | 0 | 23 | 22 | 6 | 0 | 2 | 5 | 7 | 87 | 244 | 18 | 45 | .296 | .377 | .408 | .785 | .221 | .112 | .316 | 9.43 | 9.02 | 0.96 | 71.00 | 1995- 2- 53-CLE | premium | premium | premium | MLB | 1997-2008 | 1993-2008 | 2006 |
| 5 | Joe Randa | 36 | 3B | R | 91 | 89 | 206 | 23 | 55 | 13 | 0 | 4 | 28 | 0 | 0 | 16 | 26 | 0 | 2 | 3 | 2 | 12 | 80 | 227 | 17 | 38 | .267 | .316 | .388 | .704 | .199 | .121 | .285 | 7.05 | 11.45 | 1.63 | 51.50 | 1991- 11- 288-KCA | premium | premium | premium | MLB | 1995-2006 | 1991-2006 | 2006 |
| 22 | Xavier Nady | 27 | 1B-RF | R | 102 | 55 | 203 | 20 | 61 | 13 | 0 | 3 | 23 | 1 | 2 | 11 | 34 | 5 | 1 | 0 | 3 | 5 | 83 | 220 | 16 | 45 | .300 | .352 | .409 | .761 | .158 | .109 | .349 | 5.00 | 15.45 | 3.09 | 67.67 | 2000- 2- 49-SDN | premium | premium | premium | MLB | 2000-2014 | 1998-2014 | 2006 |
| 41 | Ryan Doumit | 25 | 1B | B | 94* | 61 | 149 | 15 | 31 | 9 | 0 | 6 | 17 | 0 | 0 | 15 | 42 | 11 | 1 | 2 | 1 | 3 | 58 | 178 | 15 | 16 | .208 | .322 | .389 | .711 | .282 | .181 | .243 | 8.43 | 23.60 | 2.80 | 24.83 | 1999- 2- 59-PIT | premium | premium | premium | MLB | 2005-2014 | 1999-2014 | 2006 |
| 26 | Jose Hernandez | 36 | SS-3B | R | 90* | 67 | 120 | 8 | 32 | 2 | 1 | 2 | 12 | 0 | 0 | 11 | 29 | 0 | 1 | 0 | 0 | 3 | 42 | 132 | 5 | 27 | .267 | .328 | .350 | .678 | .175 | .083 | .337 | 8.33 | 21.97 | 2.64 | 60.00 | 1987- UDFA -TEX | premium | premium | premium | MLB | 1991-2006 | 1987-2009 | 2006 |
| 11 | Humberto Cota | 27 | C | R | 62* | 38 | 100 | 5 | 19 | 1 | 0 | 0 | 5 | 0 | 0 | 8 | 26 | 0 | 1 | 1 | 0 | 3 | 20 | 110 | 1 | 18 | .190 | .248 | .200 | .448 | .090 | .010 | .253 | 7.27 | 23.64 | 3.25 | 0.00 | 1995- UDFA -ATL | premium | premium | premium | MLB | 2001-2007 | 1997-2016 | 2006 |
| 57 | Zach Duke | 23 | P | L | 33 | 68 | 2 | 13 | 3 | 0 | 0 | 7 | 0 | 0 | 1 | 32 | 0 | 9 | 0 | 0 | 0 | 16 | 78 | 3 | 10 | .191 | .203 | .235 | .438 | .059 | .044 | .361 | 1.28 | 41.03 | 32.00 | 0.00 | 2001- 20- 594-PIT | premium | premium | premium | MLB | 2005-2019 | 2002-2019 | 2006 | |
| 43 | Paul Maholm | 24 | P | L | 28 | 55 | 3 | 6 | 0 | 0 | 0 | 2 | 0 | 0 | 3 | 31 | 0 | 1 | 0 | 0 | 2 | 6 | 59 | 0 | 6 | .109 | .155 | .109 | .264 | .055 | .000 | .250 | 5.08 | 52.54 | 10.33 | 0.00 | 2003- 1- 8-PIT | premium | premium | premium | MLB | 2005-2014 | 2001-2014 | 2006 | |
| 53,45 | Ian Snell | 24 | P | R | 35 | 54 | 2 | 3 | 1 | 0 | 0 | 2 | 0 | 0 | 2 | 28 | 0 | 9 | 0 | 0 | 1 | 4 | 65 | 1 | 2 | .056 | .089 | .074 | .163 | .056 | .018 | .115 | 3.08 | 43.08 | 14.00 | 0.00 | 2000- 26- 779-PIT | premium | premium | premium | MLB | 2004-2010 | 2000-2013 | 2006 | |
| 52 | Victor Santos | 29 | P | R | 25 | 38 | 4 | 6 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 13 | 0 | 6 | 0 | 0 | 1 | 7 | 44 | 1 | 5 | .158 | .158 | .184 | .342 | .026 | .026 | .240 | 0.00 | 29.55 | 0.00 | 0.00 | 1995- UDFA -DET | premium | premium | premium | MLB | 2001-2007 | 1996-2010 | 2006 | |
| 48 | Oliver Perez | 24 | P | L | 16 | 25 | 0 | 3 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 8 | 0 | 1 | 0 | 0 | 0 | 3 | 26 | 0 | 3 | .120 | .120 | .120 | .240 | .040 | .000 | .176 | 0.00 | 30.77 | 0.00 | 0.00 | 1999- UDFA -SDN | premium | premium | premium | MLB | 2002-2022 | 1999-2023 | 2006 | |
| 28 | Carlos Maldonado | 27 | C | R | 8 | 19 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 10 | 0 | 0 | 0 | 1 | 0 | 2 | 20 | 0 | 2 | .105 | .150 | .105 | .255 | .105 | .000 | .222 | 5.00 | 50.00 | 10.00 | 0.00 | 1995- UDFA -SEA | premium | premium | premium | MLB | 2006-2012 | 1996-2013 | 2006 | |
| 50 | Tom Gorzelanny | 23 | P | R | 11 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 21 | 0 | 0 | .000 | .050 | .000 | .050 | .053 | .000 | .000 | 4.76 | 52.38 | 11.00 | 0.00 | 2003- 2- 45-PIT | premium | premium | premium | MLB | 2005-2016 | 2002-2017 | 2006 | |
| 53 | Mike Edwards | 29 | 3B | R | 14 | 16 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 1 | 0 | 0 | 1 | 3 | 18 | 0 | 3 | .188 | .235 | .188 | .423 | .063 | .000 | .273 | 5.56 | 27.78 | 5.00 | 0.00 | 1995- 9- 250-CLE | premium | premium | premium | MLB | 2003-2006 | 1995-2007 | 2006 | |
| 10 | Rajai Davis | 25 | RF | R | 20 | 14 | 1 | 2 | 1 | 0 | 0 | 0 | 1 | 3 | 2 | 3 | 0 | 1 | 0 | 0 | 0 | 3 | 17 | 1 | 1 | .143 | .250 | .214 | .464 | .071 | .071 | .182 | 11.76 | 17.65 | 1.50 | 0.00 | 2001- 38-1134-PIT | premium | premium | premium | MLB | 2006-2019 | 2001-2019 | 2006 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 32 | Shawn Chacon | 28 | P | R | 9 | 13 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 5 | 0 | 2 | 0 | 0 | 0 | 2 | 15 | 1 | 0 | .077 | .077 | .154 | .231 | .077 | .077 | .125 | 0.00 | 33.33 | 0.00 | 0.00 | 1996- 3- 86-COL | premium | premium | premium | MLB | 2001-2008 | 1996-2009 | 2006 | |
| 32 | Kip Wells | 29 | P | R | 6 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 1 | 0 | 0 | 0 | 1 | 12 | 0 | 1 | .091 | .091 | .091 | .182 | .000 | .000 | .333 | 0.00 | 66.67 | 0.00 | 0.00 | 1998- 1- 16-CHA | premium | premium | premium | MLB | 1999-2012 | 1997-2013 | 2006 | |
| 27 | Shane Youman | 26 | P | L | 5 | 7 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3 | 7 | 0 | 3 | .429 | .429 | .429 | .858 | .000 | .000 | .750 | 0.00 | 42.86 | 0.00 | 0.00 | 2001- 43-1280-PIT | premium | premium | premium | MLB | 2006-2007 | 1999-2016 | 2006 | |
| 49 | Marty McLeary | 31 | P | R | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 60.00 | 0.00 | 0.00 | 1997- 10- 311-BOS | premium | premium | premium | MLB | 2004-2007 | 1997-2010 | 2006 | |
| 16 | Salomon Torres | 34 | P | R | 91 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 1 | .200 | .200 | .200 | .400 | .000 | .000 | .500 | 0.00 | 60.00 | 0.00 | 0.00 | 1989- UDFA -SFN | premium | premium | premium | MLB | 1993-2008 | 1991-2008 | 2006 | |
| 22 | Ryan Vogelsong | 28 | P | R | 18 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 1 | .333 | .600 | .333 | .933 | .667 | .000 | 1.000 | 40.00 | 40.00 | 1.00 | 0.00 | 1998- 5- 158-SFN | premium | premium | premium | MLB | 2000-2016 | 1998-2016 | 2006 | |
| 25 | Damaso Marte | 31 | P | L | 72 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1992- UDFA -SEA | premium | premium | premium | MLB | 1999-2010 | 1995-2011 | 2006 | |
| 37 | Yurendell Decaster | 26 | DH | R | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1996- UDFA -TBA | premium | premium | premium | MLB | 2006-2006 | 1998-2015 | 2006 | |
| 55 | Matt Capps | 22 | P | R | 82 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .333 | .000 | .333 | .500 | .000 | .000 | 33.33 | 33.33 | 1.00 | 0.00 | 2002- 7- 193-PIT | premium | premium | premium | MLB | 2005-2012 | 2002-2016 | 2006 | |
| 39,34 | John Grabow | 27 | P | L | 68 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1997- 3- 92-PIT | premium | premium | premium | MLB | 2003-2011 | 1997-2011 | 2006 | |
| 51 | Michael Gonzalez | 28 | P | R | 51 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1997- 30- 902-PIT | premium | premium | premium | MLB | 2003-2013 | 1997-2016 | 2006 | |
| Totals: | 2207 | 5558 | 691 | 1462 | 286 | 17 | 141 | 656 | 68 | 23 | 459 | 1200 | 89 | 62 | 49 | 49 | 153 | 2205 | 6217 | 444 | 1018 | .263 | .327 | .397 | .723 | .224 | .134 | .310 | 7.38 | 19.30 | 2.61 | 39.42 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 16 | Salomon Torres | 34 | R | 3 | 6 | 3.28 | 94 | 0 | 0 | 0 | 94 | 24 | 12 | 93.1 | 98 | 42 | 34 | 6 | 38 | 72 | 3 | 0 | 0 | 1.46 | 9.45 | 0.58 | 3.66 | 6.94 | 4.05 | 1.89 | 1989- UDFA -SFN | premium | premium | premium | MLB | 1993-2008 | 1991-2008 | 2006 |
| 55 | Matt Capps | 22 | R | 9 | 1 | 3.79 | 85 | 0 | 0 | 0 | 85 | 15 | 1 | 80.2 | 81 | 37 | 34 | 12 | 12 | 56 | 4 | 0 | 3 | 1.15 | 9.04 | 1.34 | 1.34 | 6.25 | 4.13 | 4.67 | 2002- 7- 193-PIT | premium | premium | premium | MLB | 2005-2012 | 2002-2016 | 2006 |
| 59 | Brian Rogers | 23 | R | 0 | 0 | 8.31 | 10 | 0 | 0 | 0 | 10 | 4 | 0 | 8.2 | 11 | 8 | 8 | 2 | 2 | 7 | 1 | 0 | 0 | 1.50 | 11.42 | 2.08 | 2.08 | 7.27 | 8.31 | 3.50 | 2003- 11- 310-DET | premium | premium | premium | MLB | 2006-2007 | 2001-2008 | 2006 |
| 48 | Oliver Perez | 24 | L | 2 | 10 | 6.63 | 15 | 15 | 0 | 0 | 0 | 0 | 0 | 76.0 | 88 | 64 | 56 | 13 | 51 | 61 | 4 | 1 | 0 | 1.83 | 10.42 | 1.54 | 6.04 | 7.22 | 7.58 | 1.20 | 1999- UDFA -SDN | premium | premium | premium | MLB | 2002-2022 | 1999-2023 | 2006 |
| 56 | Britt Reames | 32 | R | 0 | 0 | 9.82 | 6 | 0 | 0 | 0 | 6 | 5 | 0 | 7.1 | 11 | 8 | 8 | 2 | 5 | 6 | 1 | 0 | 0 | 2.18 | 13.50 | 2.45 | 6.14 | 7.36 | 9.82 | 1.20 | 1995- 17- 463-SLN | premium | premium | premium | MLB | 2000-2006 | 1992-2006 | 2006 |
| 39,34 | John Grabow | 27 | L | 4 | 2 | 4.13 | 72 | 0 | 0 | 0 | 72 | 17 | 0 | 69.2 | 68 | 34 | 32 | 7 | 30 | 66 | 0 | 0 | 3 | 1.41 | 8.78 | 0.90 | 3.88 | 8.53 | 4.39 | 2.20 | 1997- 3- 92-PIT | premium | premium | premium | MLB | 2003-2011 | 1997-2011 | 2006 |
| 50 | Tom Gorzelanny | 23 | L | 2 | 5 | 3.79 | 11 | 11 | 0 | 0 | 0 | 0 | 0 | 61.2 | 50 | 29 | 26 | 3 | 31 | 40 | 3 | 0 | 4 | 1.31 | 7.30 | 0.44 | 4.52 | 5.84 | 4.23 | 1.29 | 2003- 2- 45-PIT | premium | premium | premium | MLB | 2005-2016 | 2002-2017 | 2006 |
| 25 | Damaso Marte | 31 | L | 1 | 7 | 3.70 | 75 | 0 | 0 | 0 | 75 | 15 | 0 | 58.1 | 51 | 30 | 24 | 5 | 31 | 63 | 3 | 1 | 0 | 1.41 | 7.87 | 0.77 | 4.78 | 9.72 | 4.63 | 2.03 | 1992- UDFA -SEA | premium | premium | premium | MLB | 1999-2010 | 1995-2011 | 2006 |
| 51 | Michael Gonzalez | 28 | L | 3 | 4 | 2.17 | 54 | 0 | 0 | 0 | 54 | 47 | 24 | 54.0 | 42 | 13 | 13 | 1 | 31 | 64 | 0 | 0 | 2 | 1.35 | 7.00 | 0.17 | 5.17 | 10.67 | 2.17 | 2.06 | 1997- 30- 902-PIT | premium | premium | premium | MLB | 2003-2013 | 1997-2016 | 2006 |
| 32 | Shawn Chacon | 28 | R | 2 | 3 | 5.48 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 46.0 | 47 | 32 | 28 | 12 | 27 | 27 | 1 | 1 | 4 | 1.61 | 9.20 | 2.35 | 5.28 | 5.28 | 6.26 | 1.00 | 1996- 3- 86-COL | premium | premium | premium | MLB | 2001-2008 | 1996-2009 | 2006 |
| 34 | Roberto Hernandez | 41 | R | 0 | 3 | 2.93 | 46 | 0 | 0 | 0 | 46 | 14 | 2 | 43.0 | 46 | 24 | 14 | 3 | 24 | 33 | 3 | 0 | 1 | 1.63 | 9.63 | 0.63 | 5.02 | 6.91 | 5.02 | 1.38 | 1986- 1- 16-CAL | premium | premium | premium | MLB | 1991-2007 | 1986-2007 | 2006 |
| 22 | Ryan Vogelsong | 28 | R | 0 | 0 | 6.39 | 20 | 0 | 0 | 0 | 20 | 7 | 0 | 38.0 | 44 | 27 | 27 | 2 | 16 | 27 | 4 | 1 | 0 | 1.58 | 10.42 | 0.47 | 3.79 | 6.39 | 6.39 | 1.69 | 1998- 5- 158-SFN | premium | premium | premium | MLB | 2000-2016 | 1998-2016 | 2006 |
| 32 | Kip Wells | 29 | R | 1 | 5 | 6.69 | 7 | 7 | 0 | 0 | 0 | 0 | 0 | 36.1 | 46 | 27 | 27 | 3 | 18 | 16 | 5 | 0 | 0 | 1.76 | 11.39 | 0.74 | 4.46 | 3.96 | 6.69 | 0.89 | 1998- 1- 16-CHA | premium | premium | premium | MLB | 1999-2012 | 1997-2013 | 2006 |
| 36 | Juan Pablo Perez | 27 | L | 0 | 1 | 8.10 | 7 | 0 | 0 | 0 | 7 | 0 | 0 | 3.1 | 5 | 3 | 3 | 1 | 1 | 3 | 0 | 0 | 0 | 1.80 | 13.50 | 2.70 | 2.70 | 8.10 | 8.10 | 3.00 | 1998- UDFA -BOS | premium | premium | premium | MLB | 2006-2013 | 2002-2016 | 2006 |
| 57 | Zach Duke | 23 | L | 10 | 15 | 4.47 | 34 | 34 | 2 | 1 | 0 | 0 | 0 | 215.1 | 255 | 116 | 107 | 17 | 68 | 117 | 8 | 1 | 7 | 1.50 | 10.66 | 0.71 | 2.84 | 4.89 | 4.85 | 1.72 | 2001- 20- 594-PIT | premium | premium | premium | MLB | 2005-2019 | 2002-2019 | 2006 |
| 27 | Shane Youman | 26 | L | 0 | 2 | 2.91 | 5 | 3 | 0 | 0 | 2 | 0 | 0 | 21.2 | 15 | 7 | 7 | 1 | 10 | 5 | 0 | 0 | 0 | 1.15 | 6.23 | 0.42 | 4.15 | 2.08 | 2.91 | 0.50 | 2001- 43-1280-PIT | premium | premium | premium | MLB | 2006-2007 | 1999-2016 | 2006 |
| 53,45 | Ian Snell | 24 | R | 14 | 11 | 4.74 | 32 | 32 | 0 | 0 | 0 | 0 | 0 | 186.0 | 198 | 104 | 98 | 29 | 74 | 169 | 8 | 0 | 0 | 1.46 | 9.58 | 1.40 | 3.58 | 8.18 | 5.03 | 2.28 | 2000- 26- 779-PIT | premium | premium | premium | MLB | 2004-2010 | 2000-2013 | 2006 |
| 43 | Paul Maholm | 24 | L | 8 | 10 | 4.76 | 30 | 30 | 0 | 0 | 0 | 0 | 0 | 176.0 | 202 | 98 | 93 | 19 | 81 | 117 | 3 | 1 | 0 | 1.61 | 10.33 | 0.97 | 4.14 | 5.98 | 5.01 | 1.44 | 2003- 1- 8-PIT | premium | premium | premium | MLB | 2005-2014 | 2001-2014 | 2006 |
| 49 | Marty McLeary | 31 | R | 2 | 0 | 2.04 | 5 | 2 | 0 | 0 | 3 | 1 | 0 | 17.2 | 17 | 5 | 4 | 1 | 6 | 8 | 1 | 0 | 0 | 1.30 | 8.66 | 0.51 | 3.06 | 4.08 | 2.55 | 1.33 | 1997- 10- 311-BOS | premium | premium | premium | MLB | 2004-2007 | 1997-2010 | 2006 |
| 54 | Jonah Bayliss | 25 | R | 1 | 1 | 4.30 | 11 | 0 | 0 | 0 | 11 | 5 | 0 | 14.2 | 13 | 7 | 7 | 1 | 11 | 15 | 2 | 0 | 1 | 1.64 | 7.98 | 0.61 | 6.75 | 9.20 | 4.30 | 1.36 | 2002- 7- 198-KCA | premium | premium | premium | MLB | 2005-2007 | 2002-2012 | 2006 |
| 44 | Josh Sharpless | 25 | R | 0 | 0 | 1.50 | 14 | 0 | 0 | 0 | 14 | 3 | 0 | 12.0 | 7 | 2 | 2 | 0 | 11 | 7 | 2 | 0 | 0 | 1.50 | 5.25 | 0.00 | 8.25 | 5.25 | 1.50 | 0.64 | 2003- 24- 705-PIT | premium | premium | premium | MLB | 2006-2007 | 2003-2009 | 2006 |
| 52 | Victor Santos | 29 | R | 5 | 9 | 5.70 | 25 | 19 | 0 | 0 | 6 | 3 | 0 | 115.1 | 150 | 80 | 73 | 16 | 42 | 81 | 5 | 0 | 0 | 1.66 | 11.71 | 1.25 | 3.28 | 6.32 | 6.24 | 1.93 | 1995- UDFA -DET | premium | premium | premium | MLB | 2001-2007 | 1996-2010 | 2006 |
| Totals: | 67 | 95 | 4.55 | 667 | 162 | 2 | 1 | 160 | 505 | 39 | 1435.0 | 1545 | 797 | 725 | 156 | 620 | 1060 | 61 | 6 | 25 | 1.51 | 9.69 | 0.98 | 3.89 | 6.65 | 5.00 | 1.71 | premium | premium | premium |