| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 15 | Brooks Conrad | 26 | 2B | B | 111 | 138 | 532 | 100 | 142 | 40 | 15 | 24 | 94 | 15 | 6 | 54 | 135 | 4 | 1 | 8 | 2 | 5 | 284 | 599 | 79 | 63 | .267 | .334 | .534 | .868 | .385 | .267 | .310 | 9.02 | 22.54 | 2.50 | 22.17 | 2001- 8- 236-HOU | premium | premium | premium | MLB | 2008-2014 | 1999-2016 | 2006 |
| 35 | Charlton Jimerson | 26 | OF | R | 96 | 123 | 470 | 56 | 116 | 27 | 6 | 18 | 45 | 28 | 8 | 23 | 183 | 4 | 3 | 1 | 3 | 2 | 209 | 501 | 51 | 65 | .247 | .287 | .445 | .732 | .289 | .198 | .363 | 4.59 | 36.53 | 7.96 | 26.11 | 2001- 5- 146-HOU | premium | premium | premium | MLB | 2006-2008 | 1998-2010 | 2006 |
| 3 | Mike Rodriguez | 25 | OF | L | 100 | 113 | 439 | 70 | 121 | 16 | 7 | 6 | 38 | 28 | 6 | 51 | 55 | 2 | 7 | 2 | 2 | 7 | 169 | 501 | 29 | 92 | .276 | .352 | .385 | .737 | .276 | .109 | .303 | 10.18 | 10.98 | 1.08 | 73.17 | 2001- 2- 54-HOU | premium | premium | premium | AAA | 1999-2009 | 2006 | |
| 18 | Joe McEwing | 33 | 3B-2B | R | 104 | 112 | 422 | 64 | 133 | 21 | 1 | 10 | 46 | 16 | 7 | 23 | 65 | 3 | 7 | 5 | 1 | 5 | 186 | 460 | 32 | 101 | .315 | .351 | .441 | .792 | .201 | .126 | .349 | 5.00 | 14.13 | 2.83 | 42.20 | 1992- 28- 783-SLN | premium | premium | premium | MLB | 1998-2006 | 1992-2007 | 2006 |
| 19 | Cody Ransom | 30 | SS-3B | R | 107 | 122 | 380 | 64 | 94 | 23 | 1 | 21 | 62 | 2 | 1 | 54 | 103 | 4 | 2 | 2 | 6 | 8 | 182 | 442 | 45 | 49 | .247 | .345 | .479 | .824 | .376 | .232 | .283 | 12.22 | 23.30 | 1.91 | 18.10 | 1998- 9- 278-SFN | premium | premium | premium | MLB | 2001-2013 | 1998-2015 | 2006 |
| 7 | Royce Huffman | 29 | 1B | R | 114 | 98 | 351 | 62 | 105 | 25 | 2 | 10 | 59 | 3 | 2 | 50 | 73 | 8 | 0 | 3 | 0 | 9 | 164 | 412 | 37 | 68 | .299 | .396 | .467 | .863 | .313 | .168 | .351 | 12.14 | 17.72 | 1.46 | 35.10 | 1999- 12- 383-HOU | premium | premium | premium | AAA | 1996-2009 | 2006 | |
| 30 | Luke Scott | 28 | OF | L | 121 | 87 | 318 | 63 | 95 | 15 | 1 | 20 | 63 | 6 | 1 | 52 | 66 | 5 | 1 | 5 | 6 | 3 | 172 | 381 | 36 | 59 | .299 | .400 | .541 | .941 | .421 | .242 | .316 | 13.65 | 17.32 | 1.27 | 15.90 | 2001- 9- 277-CLE | premium | premium | premium | MLB | 2005-2013 | 2000-2015 | 2006 |
| 9 | Brian Gordon | 27 | OF | L | 102 | 102 | 303 | 48 | 73 | 21 | 3 | 16 | 59 | 1 | 3 | 28 | 110 | 3 | 4 | 2 | 2 | 2 | 148 | 340 | 40 | 33 | .241 | .310 | .488 | .798 | .333 | .247 | .318 | 8.24 | 32.35 | 3.93 | 18.94 | 1997- 7- 233-ARI | premium | premium | premium | MLB | 2008-2011 | 1997-2014 | 2006 |
| 16 | Humberto Quintero | 26 | C | R | 103 | 82 | 292 | 39 | 87 | 21 | 2 | 4 | 37 | 4 | 0 | 19 | 48 | 7 | 1 | 3 | 0 | 16 | 124 | 322 | 27 | 60 | .298 | .352 | .425 | .777 | .205 | .127 | .342 | 5.90 | 14.91 | 2.53 | 73.00 | 1997- UDFA -CHA | premium | premium | premium | MLB | 2003-2014 | 1999-2016 | 2006 |
| 23 | Hector Gimenez | 23 | C | B | 94 | 76 | 275 | 31 | 75 | 8 | 0 | 8 | 37 | 2 | 3 | 24 | 42 | 1 | 0 | 2 | 3 | 3 | 107 | 302 | 16 | 59 | .273 | .331 | .389 | .720 | .200 | .116 | .295 | 7.95 | 13.91 | 1.75 | 34.38 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2006-2013 | 2002-2016 | 2006 |
| 5 | Jesse Garcia | 32 | SS | R | 88 | 73 | 255 | 33 | 66 | 14 | 1 | 6 | 26 | 5 | 1 | 7 | 48 | 2 | 7 | 2 | 1 | 8 | 100 | 273 | 21 | 45 | .259 | .282 | .392 | .674 | .176 | .133 | .296 | 2.56 | 17.58 | 6.86 | 42.50 | 1993- 26- 735-BAL | premium | premium | premium | MLB | 1999-2005 | 1993-2008 | 2006 |
| 33 | Alan Zinter | 38 | 1B | B | 112 | 99 | 212 | 41 | 55 | 11 | 2 | 12 | 44 | 1 | 0 | 35 | 63 | 0 | 0 | 1 | 2 | 5 | 106 | 248 | 25 | 30 | .259 | .363 | .500 | .863 | .410 | .241 | .312 | 14.11 | 25.40 | 1.80 | 17.67 | 1989- 1- 24-NYN | premium | premium | premium | MLB | 2002-2004 | 1987-2007 | 2006 |
| - | J.R. House | 26 | 1B | R | 141* | 31 | 114 | 25 | 47 | 15 | 0 | 5 | 36 | 0 | 0 | 9 | 15 | 1 | 0 | 4 | 1 | 4 | 77 | 128 | 20 | 27 | .412 | .445 | .675 | 1.120 | .342 | .263 | .429 | 7.03 | 11.72 | 1.67 | 22.80 | 1999- 5- 152-PIT | premium | premium | premium | MLB | 2003-2008 | 1999-2011 | 2006 |
| 6 | Wade Robinson | 25 | SS-2B | L | 27 | 79 | 5 | 26 | 1 | 0 | 0 | 10 | 0 | 2 | 5 | 15 | 0 | 2 | 1 | 0 | 0 | 27 | 87 | 1 | 25 | .329 | .365 | .342 | .707 | .051 | .013 | .400 | 5.75 | 17.24 | 3.00 | 0.00 | 2003- 12- 359-HOU | premium | premium | premium | AAA | 2000-2008 | 2006 | ||
| 1 | Eric Bruntlett | 28 | OF | R | 99* | 22 | 73 | 11 | 16 | 3 | 1 | 1 | 7 | 3 | 2 | 17 | 13 | 2 | 1 | 0 | 0 | 0 | 24 | 93 | 5 | 11 | .219 | .380 | .329 | .709 | .356 | .110 | .254 | 18.28 | 13.98 | 0.76 | 73.00 | 2000- 9- 277-HOU | premium | premium | premium | MLB | 2003-2009 | 1997-2010 | 2006 |
| - | Jason Lane | 29 | OF | R | 12 | 46 | 7 | 12 | 2 | 0 | 1 | 11 | 1 | 0 | 5 | 16 | 1 | 0 | 3 | 0 | 4 | 17 | 55 | 3 | 9 | .261 | .327 | .370 | .697 | .239 | .109 | .344 | 9.09 | 29.09 | 3.20 | 46.00 | 1999- 6- 203-HOU | premium | premium | premium | MLB | 2002-2014 | 1998-2015 | 2006 | |
| 32 | Chris Sampson | 28 | P | R | 35 | 46 | 9 | 18 | 2 | 0 | 0 | 7 | 1 | 0 | 1 | 12 | 0 | 3 | 0 | 0 | 1 | 20 | 50 | 2 | 16 | .391 | .404 | .435 | .839 | .087 | .044 | .529 | 2.00 | 24.00 | 12.00 | 0.00 | 1999- 8- 263-HOU | premium | premium | premium | MLB | 2006-2010 | 1999-2011 | 2006 | |
| 22 | Jared Gothreaux | 26 | P | R | 21 | 38 | 2 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 18 | 0 | 5 | 0 | 0 | 2 | 2 | 43 | 0 | 2 | .053 | .053 | .053 | .106 | .000 | .000 | .100 | 0.00 | 41.86 | 0.00 | 0.00 | 2002- 16- 491-HOU | premium | premium | premium | AAA | 1999-2010 | 2006 | ||
| - | Eric Munson | 28 | OF-C | L | 9 | 32 | 6 | 8 | 1 | 0 | 2 | 8 | 0 | 0 | 3 | 4 | 2 | 0 | 0 | 0 | 1 | 15 | 37 | 3 | 5 | .250 | .351 | .469 | .820 | .313 | .219 | .231 | 8.11 | 10.81 | 1.33 | 16.00 | 1999- 1- 3-DET | premium | premium | premium | MLB | 2000-2009 | 1997-2011 | 2006 | |
| 48 | Jason Hirsh | 24 | P | R | 15 | 31 | 3 | 4 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 14 | 1 | 3 | 0 | 0 | 0 | 4 | 37 | 0 | 4 | .129 | .206 | .129 | .335 | .065 | .000 | .235 | 5.41 | 37.84 | 7.00 | 0.00 | 2003- 2- 59-HOU | premium | premium | premium | MLB | 2006-2008 | 2003-2013 | 2006 | |
| 14 | Philip Barzilla | 27 | P | L | 19 | 29 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 12 | 0 | 5 | 0 | 0 | 0 | 3 | 34 | 0 | 3 | .103 | .103 | .103 | .206 | -0.034 | .000 | .176 | 0.00 | 35.29 | 0.00 | 0.00 | 2001- 4- 116-HOU | premium | premium | premium | MLB | 2006-2006 | 2000-2010 | 2006 | |
| - | Derek Nicholson | 30 | OF | L | 9 | 26 | 5 | 6 | 1 | 0 | 3 | 6 | 0 | 0 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 16 | 31 | 4 | 2 | .231 | .355 | .615 | .970 | .577 | .384 | .167 | 16.13 | 16.13 | 1.00 | 8.67 | 1998- 16- 482-HOU | premium | premium | premium | AAA | 1997-2009 | 2006 | ||
| 38 | Ezequiel Astacio | 26 | P | R | 18 | 25 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 15 | 0 | 5 | 0 | 0 | 0 | 4 | 30 | 1 | 2 | .120 | .120 | .160 | .280 | .040 | .040 | .300 | 0.00 | 50.00 | 0.00 | 0.00 | 1998- UDFA -PHI | premium | premium | premium | MLB | 2005-2006 | 2001-2011 | 2006 | |
| 45 | Chris Baker | 28 | P | R | 18 | 16 | 1 | 1 | 1 | 0 | 0 | 3 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | 0 | 0 | 2 | 17 | 1 | 0 | .063 | .118 | .125 | .243 | .125 | .062 | .125 | 5.88 | 47.06 | 8.00 | 0.00 | 1999- 29- 883-TOR | premium | premium | premium | AAA | 1999-2007 | 2006 | ||
| - | Morgan Ensberg | 30 | 3B | R | 3 | 12 | 2 | 6 | 2 | 0 | 2 | 7 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 1 | 14 | 15 | 4 | 2 | .500 | .600 | 1.167 | 1.767 | .917 | .667 | .444 | 20.00 | 6.67 | 0.33 | 6.00 | 1998- 9- 272-HOU | premium | premium | premium | MLB | 2000-2008 | 1995-2008 | 2006 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 21 | Mark McLemore | 25 | P | L | 13 | 9 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 12 | 0 | 0 | .000 | .182 | .000 | .182 | .222 | .000 | .000 | 16.67 | 25.00 | 1.50 | 0.00 | 2002- 4- 131-HOU | premium | premium | premium | MLB | 2007-2007 | 2000-2011 | 2006 | |
| - | Chris Burke | 26 | OF-2B | R | 2 | 8 | 2 | 4 | 1 | 0 | 1 | 2 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 8 | 9 | 2 | 2 | .500 | .556 | 1.000 | 1.556 | .750 | .500 | .500 | 11.11 | 11.11 | 1.00 | 8.00 | 2001- 1- 10-HOU | premium | premium | premium | MLB | 2004-2009 | 1999-2010 | 2006 | |
| 39 | Taylor Buchholz | 24 | P | R | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 57.14 | 0.00 | 0.00 | 2000- 6- 175-PHI | premium | premium | premium | MLB | 2006-2011 | 2000-2011 | 2006 | |
| 37 | Roberto Giron | 30 | P | R | 36 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 6 | 0 | 1 | .167 | .167 | .167 | .334 | .000 | .000 | .200 | 0.00 | 16.67 | 0.00 | 0.00 | premium | premium | premium | AAA | 1995-2013 | 2006 | |||
| 50 | Travis Driskill | 34 | P | R | 40 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 1993- 4- 111-CLE | premium | premium | premium | MLB | 2002-2007 | 1991-2007 | 2006 | |
| - | Wandy Rodriguez | 27 | P | B | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 20.00 | 0.00 | 0.00 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2005-2015 | 2001-2015 | 2006 | |
| - | Brandon Backe | 28 | P | R | 3 | 5 | 2 | 3 | 2 | 0 | 0 | 3 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 7 | 2 | 1 | .600 | .714 | 1.000 | 1.714 | .800 | .400 | .600 | 28.57 | 0.00 | 0.00 | 0.00 | 1998- 18- 552-TBA | premium | premium | premium | MLB | 2002-2009 | 1998-2009 | 2006 | |
| 24 | Matt Albers | 23 | P | L | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 16.67 | 0.00 | 0.00 | 2001- 23- 686-HOU | premium | premium | premium | MLB | 2006-2019 | 2002-2019 | 2006 | |
| 31 | David Lee | 33 | P | R | 16 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 1995- 23- 627-COL | premium | premium | premium | MLB | 1999-2004 | 1996-2006 | 2006 | |
| 44 | Brandon Puffer | 30 | P | R | 26 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1994- 27- 743-MIN | premium | premium | premium | MLB | 2002-2005 | 1994-2008 | 2006 | |
| - | Roger Clemens | 43 | P | R | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1983- 1- 19-BOS | premium | premium | premium | MLB | 1984-2007 | 1982-2012 | 2006 | |
| 20 | Mike Gallo | 29 | P | L | 25 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 0 | 1 | .500 | .500 | .500 | 1.000 | .000 | .000 | 1.000 | 0.00 | 33.33 | 0.00 | 0.00 | 1999- 5- 173-HOU | premium | premium | premium | MLB | 2003-2006 | 1997-2010 | 2006 | |
| - | Kevin Orie | 33 | 3B | R | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1993- 1- 29-CHN | premium | premium | premium | MLB | 1997-2002 | 1993-2006 | 2006 | |
| 36 | Joe Valentine | 26 | P | R | 15 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1999- 26- 789-CHA | premium | premium | premium | MLB | 2003-2005 | 1999-2010 | 2006 | |
| 43 | Steve Kent | 27 | P | B | 21 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1999- 9- 275-SEA | premium | premium | premium | MLB | 2002-2002 | 1999-2012 | 2006 | |
| 10 | Jailen Peguero | 25 | P | R | 15 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2000- UDFA -HOU | premium | premium | premium | MLB | 2007-2008 | 2002-2021 | 2006 | |
| Totals: | 1689 | 4881 | 753 | 1323 | 274 | 42 | 170 | 716 | 117 | 43 | 476 | 1162 | 50 | 63 | 44 | 29 | 87 | 2191 | 5514 | 486 | 837 | .271 | .339 | .449 | .788 | .291 | .178 | .321 | 8.63 | 21.07 | 2.44 | 28.71 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 38 | Ezequiel Astacio | 26 | R | 8 | 4 | 4.86 | 21 | 17 | 0 | 0 | 4 | 1 | 0 | 92.2 | 95 | 51 | 50 | 15 | 43 | 76 | 4 | 1 | 0 | 1.49 | 9.23 | 1.46 | 4.18 | 7.38 | 4.95 | 1.77 | 1998- UDFA -PHI | premium | premium | premium | MLB | 2005-2006 | 2001-2011 | 2006 |
| 37 | Roberto Giron | 30 | R | 2 | 5 | 4.78 | 47 | 6 | 0 | 0 | 41 | 29 | 13 | 86.2 | 93 | 48 | 46 | 11 | 32 | 66 | 3 | 1 | 0 | 1.44 | 9.66 | 1.14 | 3.32 | 6.85 | 4.98 | 2.06 | premium | premium | premium | AAA | 1995-2013 | 2006 | ||
| 45 | Chris Baker | 28 | R | 9 | 4 | 2.68 | 26 | 6 | 0 | 0 | 20 | 5 | 1 | 84.0 | 77 | 33 | 25 | 5 | 28 | 40 | 0 | 0 | 0 | 1.25 | 8.25 | 0.54 | 3.00 | 4.29 | 3.54 | 1.43 | 1999- 29- 883-TOR | premium | premium | premium | AAA | 1999-2007 | 2006 | |
| - | Justin Huisman | 27 | R | 0 | 0 | 11.25 | 6 | 0 | 0 | 0 | 6 | 0 | 0 | 8.0 | 11 | 10 | 10 | 0 | 4 | 4 | 0 | 0 | 0 | 1.88 | 12.38 | 0.00 | 4.50 | 4.50 | 11.25 | 1.00 | 2000- 15- 437-COL | premium | premium | premium | MLB | 2004-2004 | 1999-2007 | 2006 |
| - | Aaron Williams | 25 | R | 0 | 1 | 4.70 | 5 | 0 | 0 | 0 | 5 | 2 | 0 | 7.2 | 10 | 4 | 4 | 0 | 3 | 5 | 1 | 0 | 0 | 1.70 | 11.74 | 0.00 | 3.52 | 5.87 | 4.70 | 1.67 | premium | premium | premium | AAA | 2002-2007 | 2006 | ||
| - | Dave Borkowski | 29 | R | 0 | 1 | 2.57 | 6 | 0 | 0 | 0 | 6 | 5 | 3 | 7.0 | 6 | 2 | 2 | 1 | 2 | 6 | 1 | 0 | 0 | 1.14 | 7.71 | 1.29 | 2.57 | 7.71 | 2.57 | 3.00 | 1995- 11- 294-DET | premium | premium | premium | MLB | 1999-2008 | 1995-2009 | 2006 |
| 50 | Travis Driskill | 34 | R | 4 | 8 | 3.20 | 52 | 0 | 0 | 0 | 52 | 38 | 15 | 64.2 | 57 | 29 | 23 | 8 | 13 | 58 | 0 | 0 | 0 | 1.08 | 7.93 | 1.11 | 1.81 | 8.07 | 4.04 | 4.46 | 1993- 4- 111-CLE | premium | premium | premium | MLB | 2002-2007 | 1991-2007 | 2006 |
| 21 | Mark McLemore | 25 | L | 2 | 3 | 2.81 | 21 | 9 | 0 | 0 | 12 | 0 | 0 | 57.2 | 48 | 27 | 18 | 5 | 38 | 52 | 0 | 0 | 0 | 1.49 | 7.49 | 0.78 | 5.93 | 8.12 | 4.21 | 1.37 | 2002- 4- 131-HOU | premium | premium | premium | MLB | 2007-2007 | 2000-2011 | 2006 |
| 44 | Brandon Puffer | 30 | R | 5 | 1 | 4.47 | 37 | 0 | 0 | 0 | 37 | 18 | 4 | 52.1 | 46 | 27 | 26 | 6 | 16 | 37 | 0 | 1 | 0 | 1.18 | 7.91 | 1.03 | 2.75 | 6.36 | 4.64 | 2.31 | 1994- 27- 743-MIN | premium | premium | premium | MLB | 2002-2005 | 1994-2008 | 2006 |
| - | Roger Clemens | 43 | R | 1 | 0 | 4.76 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 5.2 | 5 | 3 | 3 | 0 | 3 | 5 | 0 | 0 | 0 | 1.41 | 7.94 | 0.00 | 4.76 | 7.94 | 4.76 | 1.67 | 1983- 1- 19-BOS | premium | premium | premium | MLB | 1984-2007 | 1982-2012 | 2006 |
| 28 | Fernando Nieve | 23 | R | 0 | 0 | 0.00 | 4 | 0 | 0 | 0 | 4 | 2 | 2 | 5.1 | 2 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 0.38 | 3.38 | 0.00 | 0.00 | 11.81 | 0.00 | 0.00 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2006-2010 | 2001-2018 | 2006 |
| 39 | Taylor Buchholz | 24 | R | 1 | 3 | 4.91 | 7 | 7 | 0 | 0 | 0 | 0 | 0 | 44.0 | 47 | 27 | 24 | 2 | 17 | 37 | 0 | 0 | 0 | 1.45 | 9.61 | 0.41 | 3.48 | 7.57 | 5.52 | 2.18 | 2000- 6- 175-PHI | premium | premium | premium | MLB | 2006-2011 | 2000-2011 | 2006 |
| 20 | Mike Gallo | 29 | L | 2 | 0 | 5.63 | 33 | 0 | 0 | 0 | 33 | 8 | 0 | 40.0 | 46 | 25 | 25 | 4 | 16 | 25 | 1 | 0 | 0 | 1.55 | 10.35 | 0.90 | 3.60 | 5.63 | 5.63 | 1.56 | 1999- 5- 173-HOU | premium | premium | premium | MLB | 2003-2006 | 1997-2010 | 2006 |
| 10 | Jailen Peguero | 25 | R | 1 | 2 | 3.47 | 21 | 0 | 0 | 0 | 21 | 6 | 1 | 36.1 | 34 | 18 | 14 | 3 | 18 | 30 | 4 | 1 | 0 | 1.43 | 8.42 | 0.74 | 4.46 | 7.43 | 4.46 | 1.67 | 2000- UDFA -HOU | premium | premium | premium | MLB | 2007-2008 | 2002-2021 | 2006 |
| 31 | David Lee | 33 | R | 1 | 1 | 4.35 | 22 | 0 | 0 | 0 | 22 | 4 | 0 | 31.0 | 30 | 16 | 15 | 3 | 22 | 34 | 1 | 0 | 0 | 1.68 | 8.71 | 0.87 | 6.39 | 9.87 | 4.65 | 1.55 | 1995- 23- 627-COL | premium | premium | premium | MLB | 1999-2004 | 1996-2006 | 2006 |
| 36 | Joe Valentine | 26 | R | 1 | 2 | 4.70 | 20 | 1 | 0 | 0 | 19 | 2 | 0 | 30.2 | 34 | 19 | 16 | 2 | 21 | 17 | 0 | 0 | 0 | 1.79 | 9.98 | 0.59 | 6.16 | 4.99 | 5.58 | 0.81 | 1999- 26- 789-CHA | premium | premium | premium | MLB | 2003-2005 | 1999-2010 | 2006 |
| 43 | Steve Kent | 27 | L | 1 | 0 | 2.43 | 27 | 0 | 0 | 0 | 27 | 9 | 2 | 29.2 | 24 | 10 | 8 | 4 | 20 | 15 | 0 | 1 | 0 | 1.48 | 7.28 | 1.21 | 6.07 | 4.55 | 3.03 | 0.75 | 1999- 9- 275-SEA | premium | premium | premium | MLB | 2002-2002 | 1999-2012 | 2006 |
| - | Wandy Rodriguez | 27 | L | 2 | 2 | 6.92 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 26.0 | 32 | 21 | 20 | 2 | 13 | 13 | 1 | 0 | 0 | 1.73 | 11.08 | 0.69 | 4.50 | 4.50 | 7.27 | 1.00 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2005-2015 | 2001-2015 | 2006 |
| 24 | Matt Albers | 23 | R | 2 | 1 | 3.96 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 25.0 | 24 | 11 | 11 | 2 | 10 | 26 | 0 | 0 | 0 | 1.36 | 8.64 | 0.72 | 3.60 | 9.36 | 3.96 | 2.60 | 2001- 23- 686-HOU | premium | premium | premium | MLB | 2006-2019 | 2002-2019 | 2006 |
| - | Brandon Backe | 28 | R | 1 | 2 | 5.31 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 20.1 | 23 | 12 | 12 | 1 | 13 | 13 | 1 | 0 | 0 | 1.77 | 10.18 | 0.44 | 5.75 | 5.75 | 5.31 | 1.00 | 1998- 18- 552-TBA | premium | premium | premium | MLB | 2002-2009 | 1998-2009 | 2006 |
| - | Trever Miller | 33 | L | 0 | 0 | 0.00 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 2.0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 13.50 | 0.00 | 0.00 | 1991- 1- 41-DET | premium | premium | premium | MLB | 1996-2011 | 1991-2011 | 2006 |
| 22 | Jared Gothreaux | 26 | R | 9 | 9 | 4.34 | 29 | 27 | 0 | 0 | 2 | 0 | 0 | 143.0 | 164 | 78 | 69 | 19 | 40 | 89 | 3 | 0 | 0 | 1.43 | 10.32 | 1.20 | 2.52 | 5.60 | 4.91 | 2.23 | 2002- 16- 491-HOU | premium | premium | premium | AAA | 1999-2010 | 2006 | |
| 48 | Jason Hirsh | 24 | R | 13 | 2 | 2.10 | 23 | 23 | 1 | 1 | 0 | 0 | 0 | 137.1 | 94 | 37 | 32 | 5 | 51 | 118 | 2 | 0 | 0 | 1.06 | 6.16 | 0.33 | 3.34 | 7.73 | 2.42 | 2.31 | 2003- 2- 59-HOU | premium | premium | premium | MLB | 2006-2008 | 2003-2013 | 2006 |
| 32 | Chris Sampson | 28 | R | 12 | 3 | 2.51 | 27 | 18 | 2 | 0 | 9 | 8 | 4 | 125.2 | 110 | 48 | 35 | 12 | 14 | 68 | 2 | 0 | 0 | 0.99 | 7.88 | 0.86 | 1.00 | 4.87 | 3.44 | 4.86 | 1999- 8- 263-HOU | premium | premium | premium | MLB | 2006-2010 | 1999-2011 | 2006 |
| 14 | Philip Barzilla | 27 | L | 8 | 5 | 3.85 | 25 | 14 | 1 | 1 | 11 | 3 | 1 | 112.1 | 114 | 57 | 48 | 5 | 48 | 80 | 1 | 1 | 0 | 1.44 | 9.13 | 0.40 | 3.85 | 6.41 | 4.57 | 1.67 | 2001- 4- 116-HOU | premium | premium | premium | MLB | 2006-2006 | 2000-2010 | 2006 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| Totals: | 85 | 59 | 3.78 | 475 | 144 | 4 | 2 | 140 | 331 | 46 | 1275.0 | 1226 | 613 | 536 | 115 | 485 | 924 | 25 | 6 | 0 | 1.34 | 8.65 | 0.81 | 3.42 | 6.52 | 4.33 | 1.91 | premium | premium | premium |