| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 5 | Matt Holliday | 26 | LF | R | 124 | 155 | 602 | 119 | 196 | 45 | 5 | 34 | 114 | 10 | 5 | 47 | 110 | 15 | 0 | 3 | 3 | 22 | 353 | 667 | 84 | 112 | .326 | .387 | .586 | .973 | .347 | .260 | .351 | 7.05 | 16.49 | 2.34 | 17.71 | 1998- 7- 210-COL | premium | premium | premium | MLB | 2004-2018 | 1998-2018 | 2006 |
| 27 | Garrett Atkins | 26 | 3B | R | 124 | 157 | 602 | 117 | 198 | 48 | 1 | 29 | 120 | 4 | 0 | 79 | 76 | 7 | 0 | 7 | 6 | 24 | 335 | 695 | 78 | 120 | .329 | .409 | .556 | .965 | .365 | .227 | .335 | 11.37 | 10.94 | 0.96 | 20.76 | 2000- 5- 137-COL | premium | premium | premium | MLB | 2003-2010 | 1998-2010 | 2006 |
| 17 | Todd Helton | 32 | 1B | L | 113 | 145 | 546 | 94 | 165 | 40 | 5 | 15 | 81 | 3 | 2 | 91 | 64 | 6 | 0 | 6 | 15 | 10 | 260 | 649 | 60 | 105 | .302 | .404 | .476 | .880 | .342 | .174 | .317 | 14.02 | 9.86 | 0.70 | 36.40 | 1995- 1- 8-COL | premium | premium | premium | MLB | 1997-2013 | 1993-2013 | 2006 |
| 11 | Brad Hawpe | 27 | RF | L | 114 | 150 | 499 | 67 | 146 | 33 | 6 | 22 | 84 | 5 | 5 | 74 | 123 | 0 | 0 | 2 | 11 | 8 | 257 | 575 | 61 | 85 | .293 | .383 | .515 | .898 | .371 | .222 | .348 | 12.87 | 21.39 | 1.66 | 22.68 | 2000- 11- 317-COL | premium | premium | premium | MLB | 2004-2013 | 1999-2013 | 2006 |
| 12 | Clint Barmes | 27 | SS | R | 77 | 131 | 478 | 57 | 105 | 26 | 4 | 7 | 56 | 5 | 4 | 22 | 72 | 9 | 19 | 7 | 6 | 2 | 160 | 535 | 37 | 68 | .220 | .264 | .335 | .599 | .163 | .115 | .241 | 4.11 | 13.46 | 3.27 | 68.29 | 2000- 10- 287-COL | premium | premium | premium | MLB | 2003-2015 | 2000-2016 | 2006 |
| 1 | Jamey Carroll | 32 | 2B | R | 102 | 136 | 463 | 84 | 139 | 23 | 5 | 5 | 36 | 10 | 12 | 56 | 66 | 3 | 9 | 3 | 1 | 10 | 187 | 534 | 33 | 106 | .300 | .377 | .404 | .781 | .220 | .104 | .339 | 10.49 | 12.36 | 1.18 | 92.60 | 1996- 14- 400-MON | premium | premium | premium | MLB | 2002-2013 | 1993-2013 | 2006 |
| 31 | Cory Sullivan | 26 | CF | L | 93 | 126 | 386 | 47 | 103 | 26 | 10 | 2 | 30 | 10 | 6 | 32 | 100 | 1 | 19 | 5 | 3 | 5 | 155 | 443 | 38 | 65 | .267 | .321 | .402 | .723 | .228 | .135 | .349 | 7.22 | 22.57 | 3.13 | 193.00 | 2001- 7- 214-COL | premium | premium | premium | MLB | 2005-2010 | 2000-2012 | 2006 |
| 8 | Yorvit Torrealba | 27 | C | R | 94 | 65 | 223 | 23 | 55 | 16 | 3 | 7 | 43 | 4 | 3 | 11 | 49 | 4 | 2 | 1 | 1 | 7 | 98 | 241 | 26 | 29 | .247 | .293 | .439 | .732 | .247 | .192 | .286 | 4.56 | 20.33 | 4.45 | 31.86 | 1994- UDFA -SFN | premium | premium | premium | MLB | 2001-2013 | 1995-2014 | 2006 |
| 21 | Choo Freeman | 26 | CF | R | 82* | 88 | 173 | 24 | 41 | 6 | 3 | 2 | 18 | 5 | 6 | 14 | 42 | 1 | 3 | 0 | 2 | 1 | 59 | 191 | 11 | 30 | .237 | .298 | .341 | .639 | .179 | .104 | .302 | 7.33 | 21.99 | 3.00 | 86.50 | 1998- 1- 36-COL | premium | premium | premium | MLB | 2004-2006 | 1998-2007 | 2006 |
| 19 | Ryan Spilborghs | 26 | CF-RF | R | 100* | 67 | 167 | 26 | 48 | 6 | 3 | 4 | 21 | 5 | 2 | 14 | 30 | 0 | 2 | 3 | 0 | 7 | 72 | 186 | 13 | 35 | .287 | .337 | .431 | .768 | .246 | .144 | .324 | 7.53 | 16.13 | 2.14 | 41.75 | 2002- 7- 201-COL | premium | premium | premium | MLB | 2005-2011 | 2000-2013 | 2006 |
| 4 | Luis Gonzalez | 27 | 2B | R | 79* | 61 | 149 | 7 | 36 | 9 | 1 | 2 | 14 | 1 | 1 | 4 | 27 | 2 | 0 | 6 | 0 | 3 | 53 | 161 | 12 | 24 | .242 | .261 | .356 | .617 | .141 | .114 | .270 | 2.48 | 16.77 | 6.75 | 74.50 | 1996- UDFA -CLE | premium | premium | premium | MLB | 2004-2006 | 1998-2008 | 2006 |
| 16 | Kazuo Matsui | 30 | 2B | B | 92 | 32 | 113 | 22 | 39 | 6 | 3 | 2 | 19 | 8 | 1 | 10 | 27 | 0 | 4 | 2 | 0 | 0 | 57 | 129 | 11 | 28 | .345 | .392 | .504 | .896 | .310 | .159 | .430 | 7.75 | 20.93 | 2.70 | 56.50 | 2003- UDFA -NYN | premium | premium | premium | MLB | 2004-2010 | 1995-2018 | 2006 |
| 55 | Danny Ardoin | 31 | C | R | 66* | 35 | 109 | 12 | 21 | 5 | 1 | 0 | 2 | 0 | 0 | 8 | 27 | 2 | 1 | 0 | 2 | 2 | 28 | 120 | 6 | 15 | .193 | .261 | .257 | .518 | .138 | .064 | .256 | 6.67 | 22.50 | 3.38 | 0.00 | 1995- 5- 120-OAK | premium | premium | premium | MLB | 2000-2008 | 1995-2009 | 2006 |
| 24 | Jason Smith | 28 | 2B | L | 99* | 49 | 99 | 9 | 26 | 1 | 0 | 5 | 13 | 3 | 0 | 7 | 29 | 2 | 0 | 0 | 1 | 1 | 42 | 108 | 6 | 20 | .263 | .324 | .424 | .748 | .263 | .161 | .323 | 6.48 | 26.85 | 4.14 | 19.80 | 1996- 43-1288-TBA | premium | premium | premium | MLB | 2001-2009 | 1997-2015 | 2006 |
| 7 | JD Closser | 26 | C | B | 78* | 32 | 97 | 10 | 19 | 3 | 1 | 2 | 11 | 0 | 1 | 12 | 23 | 1 | 1 | 1 | 2 | 1 | 30 | 112 | 6 | 13 | .196 | .288 | .309 | .597 | .227 | .113 | .233 | 10.71 | 20.54 | 1.92 | 48.50 | 1998- 5- 163-ARI | premium | premium | premium | MLB | 2004-2006 | 1998-2011 | 2006 |
| 14 | Troy Tulowitzki | 21 | SS | R | 25 | 96 | 15 | 23 | 2 | 0 | 1 | 6 | 3 | 0 | 10 | 25 | 1 | 1 | 0 | 3 | 1 | 28 | 108 | 3 | 20 | .240 | .318 | .292 | .610 | .188 | .052 | .314 | 9.26 | 23.15 | 2.50 | 96.00 | 2005- 1- 7-COL | premium | premium | premium | MLB | 2006-2019 | 2003-2019 | 2006 | |
| 20 | Chris Iannetta | 23 | C | R | 21 | 77 | 12 | 20 | 4 | 0 | 2 | 10 | 0 | 1 | 13 | 17 | 1 | 1 | 1 | 2 | 1 | 30 | 93 | 6 | 14 | .260 | .370 | .390 | .760 | .286 | .130 | .305 | 13.98 | 18.28 | 1.31 | 38.50 | 2004- 4- 110-COL | premium | premium | premium | MLB | 2006-2019 | 2002-2019 | 2006 | |
| 20 | Miguel Ojeda | 31 | C | R | 25 | 74 | 5 | 17 | 3 | 0 | 2 | 11 | 0 | 0 | 8 | 16 | 0 | 0 | 0 | 2 | 6 | 26 | 82 | 5 | 12 | .230 | .305 | .351 | .656 | .230 | .121 | .268 | 9.76 | 19.51 | 2.00 | 37.00 | 1993- UDFA -PIT | premium | premium | premium | MLB | 2003-2006 | 1993-2012 | 2006 | |
| 32 | Jason Jennings | 27 | P | L | 30 | 62 | 3 | 8 | 1 | 0 | 0 | 2 | 0 | 0 | 3 | 12 | 0 | 10 | 0 | 0 | 0 | 9 | 75 | 1 | 7 | .129 | .169 | .145 | .314 | .065 | .016 | .160 | 4.00 | 16.00 | 4.00 | 0.00 | 1999- 1- 16-COL | premium | premium | premium | MLB | 2001-2009 | 1997-2011 | 2006 | |
| 26 | Jeff Francis | 25 | P | L | 31 | 61 | 3 | 7 | 0 | 0 | 0 | 6 | 0 | 0 | 8 | 20 | 0 | 9 | 2 | 0 | 0 | 7 | 80 | 0 | 7 | .115 | .211 | .115 | .326 | .131 | .000 | .163 | 10.00 | 25.00 | 2.50 | 0.00 | 2002- 1- 9-COL | premium | premium | premium | MLB | 2004-2015 | 2002-2015 | 2006 | |
| 16 | Eli Marrero | 32 | 1B-C | R | 102* | 30 | 60 | 7 | 13 | 3 | 0 | 4 | 10 | 3 | 0 | 11 | 16 | 1 | 0 | 0 | 1 | 1 | 28 | 72 | 7 | 6 | .217 | .347 | .467 | .814 | .483 | .250 | .225 | 15.28 | 22.22 | 1.45 | 15.00 | 1993- 3- 88-SLN | premium | premium | premium | MLB | 1997-2006 | 1993-2007 | 2006 |
| 3 | Jorge Piedra | 27 | DH | L | 43 | 59 | 4 | 10 | 2 | 0 | 3 | 10 | 1 | 0 | 3 | 22 | 1 | 0 | 0 | 0 | 2 | 21 | 63 | 5 | 5 | .169 | .222 | .356 | .578 | .254 | .187 | .206 | 4.76 | 34.92 | 7.33 | 19.67 | 1997- UDFA -LAN | premium | premium | premium | MLB | 2004-2006 | 1999-2010 | 2006 | |
| 28 | Aaron Cook | 27 | P | R | 31 | 58 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 21 | 0 | 13 | 0 | 0 | 0 | 3 | 75 | 0 | 3 | .052 | .113 | .052 | .165 | .069 | .000 | .081 | 5.33 | 28.00 | 5.25 | 0.00 | 1997- 2- 70-COL | premium | premium | premium | MLB | 2002-2012 | 1997-2013 | 2006 | |
| 10 | Jeff Baker | 25 | RF | R | 18 | 57 | 13 | 21 | 7 | 2 | 5 | 21 | 2 | 0 | 1 | 14 | 0 | 0 | 0 | 0 | 0 | 47 | 58 | 14 | 7 | .368 | .379 | .825 | 1.204 | .509 | .457 | .421 | 1.72 | 24.14 | 14.00 | 11.40 | 2002- 4- 111-COL | premium | premium | premium | MLB | 2005-2015 | 2000-2015 | 2006 | |
| 15 | Jeff Salazar | 25 | CF | L | 19 | 53 | 13 | 15 | 4 | 0 | 1 | 8 | 2 | 0 | 11 | 16 | 1 | 1 | 1 | 2 | 0 | 22 | 67 | 5 | 10 | .283 | .409 | .415 | .824 | .377 | .132 | .378 | 16.42 | 23.88 | 1.45 | 53.00 | 2002- 8- 231-COL | premium | premium | premium | MLB | 2006-2009 | 2002-2012 | 2006 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 37 | Josh Fogg | 29 | P | R | 32 | 51 | 5 | 5 | 1 | 0 | 0 | 2 | 0 | 0 | 3 | 20 | 1 | 15 | 0 | 0 | 0 | 6 | 70 | 1 | 4 | .098 | .164 | .118 | .282 | .078 | .020 | .161 | 4.29 | 28.57 | 6.67 | 0.00 | 1998- 3- 89-CHA | premium | premium | premium | MLB | 2001-2009 | 1996-2010 | 2006 | |
| 49 | Byung-Hyun Kim | 27 | P | R | 26 | 50 | 4 | 8 | 1 | 0 | 0 | 4 | 0 | 0 | 1 | 15 | 0 | 6 | 0 | 0 | 2 | 9 | 57 | 1 | 7 | .160 | .176 | .180 | .356 | .040 | .020 | .229 | 1.75 | 26.32 | 15.00 | 0.00 | 1999- UDFA -ARI | premium | premium | premium | MLB | 1999-2007 | 1999-2010 | 2006 | |
| 6 | Omar Quintanilla | 24 | SS | L | 11 | 34 | 3 | 6 | 1 | 1 | 0 | 3 | 1 | 1 | 3 | 9 | 0 | 1 | 0 | 1 | 1 | 9 | 38 | 2 | 4 | .176 | .243 | .265 | .508 | .176 | .089 | .240 | 7.89 | 23.68 | 3.00 | 0.00 | 2003- 1- 33-OAK | premium | premium | premium | MLB | 2005-2014 | 2001-2017 | 2006 | |
| 9 | Vinny Castilla | 38 | 1B | R | 76 | 15 | 21 | 2 | 4 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 7 | 22 | 1 | 3 | .190 | .227 | .333 | .560 | .143 | .143 | .176 | 0.00 | 13.64 | 0.00 | 21.00 | 1990- UDFA -ATL | premium | premium | premium | MLB | 1991-2006 | 1990-2006 | 2006 |
| 43 | Ryan Shealy | 26 | 1B | R | 102 | 5 | 9 | 2 | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4 | 9 | 2 | 0 | .222 | .222 | .444 | .666 | .222 | .222 | .400 | 0.00 | 44.44 | 0.00 | 0.00 | 2002- 11- 321-COL | premium | premium | premium | MLB | 2005-2010 | 1999-2011 | 2006 |
| 45 | Zach Day | 28 | P | R | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 1996- 5- 149-NYA | premium | premium | premium | MLB | 2002-2006 | 1996-2008 | 2006 | |
| 55 | Alvin Colina | 24 | C | R | 2 | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 1 | .200 | .200 | .200 | .400 | .000 | .000 | .250 | 0.00 | 20.00 | 0.00 | 0.00 | 1998- UDFA -COL | premium | premium | premium | MLB | 2006-2006 | 2000-2013 | 2006 | |
| 39 | Tom Martin | 36 | P | L | 65 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 25.00 | 0.00 | 0.00 | 1988- 6- 139-BAL | premium | premium | premium | MLB | 1997-2007 | 1989-2009 | 2006 | |
| 61 | Ramon Ramirez | 24 | P | R | 59 | 4 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 2 | 5 | 0 | 2 | .500 | .500 | .500 | 1.000 | .000 | .000 | 1.000 | 0.00 | 40.00 | 0.00 | 0.00 | 1996- UDFA -TEX | premium | premium | premium | MLB | 2006-2014 | 2002-2022 | 2006 | |
| 46 | Miguel Asencio | 25 | P | R | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 66.67 | 0.00 | 0.00 | 1998- UDFA -PHI | premium | premium | premium | MLB | 2002-2006 | 2001-2008 | 2006 | |
| 47 | Justin Hampson | 26 | P | L | 5 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .250 | .000 | .250 | .333 | .000 | .000 | 20.00 | 20.00 | 1.00 | 0.00 | 1999- 28- 850-COL | premium | premium | premium | MLB | 2006-2012 | 2000-2013 | 2006 | |
| 38 | Ubaldo Jimenez | 22 | P | R | 2 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 1 | .333 | .333 | .333 | .666 | .000 | .000 | .500 | 0.00 | 33.33 | 0.00 | 0.00 | 2001- UDFA -COL | premium | premium | premium | MLB | 2006-2017 | 2002-2017 | 2006 | |
| 51 | Sun-Woo Kim | 28 | P | R | 6 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 0 | 1.000 | 1.000 | 2.000 | 3.000 | 1.000 | 1.000 | 1.000 | 0.00 | 0.00 | 0.00 | 0.00 | 1997- UDFA -BOS | premium | premium | premium | MLB | 2001-2006 | 1998-2007 | 2006 | |
| 54 | Denny Bautista | 25 | P | R | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2000- UDFA -MIA | premium | premium | premium | MLB | 2004-2010 | 2000-2015 | 2006 | |
| 47 | Scott Dohmann | 28 | P | R | 25 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2000- 6- 167-COL | premium | premium | premium | MLB | 2004-2008 | 1999-2011 | 2006 | |
| 51 | Juan Morillo | 22 | P | R | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2001- UDFA -COL | premium | premium | premium | MLB | 2006-2025 | 2003-2025 | 2006 | |
| 49 | Jose Mesa | 40 | P | R | 76 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1981- UDFA -TOR | premium | premium | premium | MLB | 1987-2007 | 1982-2007 | 2006 | |
| 41 | Jeremy Affeldt | 27 | P | L | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1997- 3- 91-KCA | premium | premium | premium | MLB | 2002-2015 | 1997-2015 | 2006 | |
| 56 | Ray King | 32 | P | L | 64 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1995- 8- 223-CIN | premium | premium | premium | MLB | 1999-2008 | 1995-2008 | 2006 | |
| Totals: | 2133 | 5562 | 813 | 1504 | 325 | 54 | 157 | 761 | 85 | 50 | 561 | 1108 | 60 | 120 | 50 | 64 | 119 | 2408 | 6353 | 536 | 968 | .270 | .341 | .433 | .774 | .270 | .163 | .310 | 8.83 | 17.44 | 1.98 | 35.43 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 35 | Nate Field | 30 | R | 1 | 1 | 4.00 | 14 | 0 | 0 | 0 | 14 | 1 | 0 | 9.0 | 9 | 4 | 4 | 2 | 5 | 14 | 1 | 0 | 0 | 1.56 | 9.00 | 2.00 | 5.00 | 14.00 | 4.00 | 2.80 | 1998- UDFA -MON | premium | premium | premium | MLB | 2002-2007 | 1998-2009 | 2006 |
| 49 | Jose Mesa | 40 | R | 1 | 5 | 3.86 | 79 | 0 | 0 | 0 | 79 | 26 | 1 | 72.1 | 73 | 32 | 31 | 9 | 36 | 39 | 4 | 1 | 0 | 1.51 | 9.08 | 1.12 | 4.48 | 4.85 | 3.98 | 1.08 | 1981- UDFA -TOR | premium | premium | premium | MLB | 1987-2007 | 1982-2007 | 2006 |
| 46 | Miguel Asencio | 25 | R | 1 | 0 | 4.70 | 3 | 1 | 0 | 0 | 2 | 0 | 0 | 7.2 | 9 | 8 | 4 | 1 | 4 | 7 | 0 | 0 | 1 | 1.70 | 10.57 | 1.17 | 4.70 | 8.22 | 9.39 | 1.75 | 1998- UDFA -PHI | premium | premium | premium | MLB | 2002-2006 | 2001-2008 | 2006 |
| 38 | Ubaldo Jimenez | 22 | R | 0 | 0 | 3.52 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 7.2 | 5 | 4 | 3 | 1 | 3 | 3 | 0 | 0 | 0 | 1.04 | 5.87 | 1.17 | 3.52 | 3.52 | 4.70 | 1.00 | 2001- UDFA -COL | premium | premium | premium | MLB | 2006-2017 | 2002-2017 | 2006 |
| 51 | Sun-Woo Kim | 28 | R | 0 | 0 | 19.29 | 6 | 0 | 0 | 0 | 6 | 1 | 0 | 7.0 | 17 | 15 | 15 | 2 | 8 | 4 | 1 | 0 | 1 | 3.57 | 21.86 | 2.57 | 10.29 | 5.14 | 19.29 | 0.50 | 1997- UDFA -BOS | premium | premium | premium | MLB | 2001-2006 | 1998-2007 | 2006 |
| 61 | Ramon Ramirez | 24 | R | 4 | 3 | 3.46 | 61 | 0 | 0 | 0 | 61 | 14 | 0 | 67.2 | 58 | 28 | 26 | 5 | 27 | 61 | 2 | 0 | 0 | 1.26 | 7.71 | 0.67 | 3.59 | 8.11 | 3.72 | 2.26 | 1996- UDFA -TEX | premium | premium | premium | MLB | 2006-2014 | 2002-2022 | 2006 |
| 40 | Brian Fuentes | 30 | L | 3 | 4 | 3.44 | 66 | 0 | 0 | 0 | 66 | 58 | 30 | 65.1 | 50 | 25 | 25 | 8 | 26 | 73 | 6 | 0 | 6 | 1.16 | 6.89 | 1.10 | 3.58 | 10.06 | 3.44 | 2.81 | 1995- 25- 678-SEA | premium | premium | premium | MLB | 2001-2012 | 1996-2012 | 2006 |
| 39 | Tom Martin | 36 | L | 2 | 0 | 5.07 | 68 | 0 | 0 | 0 | 68 | 9 | 0 | 60.1 | 62 | 37 | 34 | 4 | 25 | 46 | 1 | 0 | 0 | 1.44 | 9.25 | 0.60 | 3.73 | 6.86 | 5.52 | 1.84 | 1988- 6- 139-BAL | premium | premium | premium | MLB | 1997-2007 | 1989-2009 | 2006 |
| 54 | Denny Bautista | 25 | R | 0 | 1 | 5.40 | 4 | 1 | 0 | 0 | 3 | 3 | 0 | 6.2 | 9 | 10 | 4 | 0 | 4 | 5 | 0 | 0 | 0 | 1.95 | 12.15 | 0.00 | 5.40 | 6.75 | 13.50 | 1.25 | 2000- UDFA -MIA | premium | premium | premium | MLB | 2004-2010 | 2000-2015 | 2006 |
| 56 | Ray King | 32 | L | 1 | 4 | 4.43 | 67 | 0 | 0 | 0 | 67 | 7 | 1 | 44.2 | 56 | 26 | 22 | 6 | 20 | 23 | 3 | 0 | 2 | 1.70 | 11.28 | 1.21 | 4.03 | 4.63 | 5.24 | 1.15 | 1995- 8- 223-CIN | premium | premium | premium | MLB | 1999-2008 | 1995-2008 | 2006 |
| 51 | Juan Morillo | 22 | R | 0 | 0 | 15.75 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 4.0 | 8 | 7 | 7 | 3 | 3 | 4 | 0 | 0 | 0 | 2.75 | 18.00 | 6.75 | 6.75 | 9.00 | 15.75 | 1.33 | 2001- UDFA -COL | premium | premium | premium | MLB | 2006-2025 | 2003-2025 | 2006 |
| 60 | Manny Corpas | 23 | R | 1 | 2 | 3.62 | 35 | 0 | 0 | 0 | 35 | 3 | 0 | 32.1 | 36 | 13 | 13 | 3 | 8 | 27 | 2 | 0 | 2 | 1.36 | 10.02 | 0.84 | 2.23 | 7.52 | 3.62 | 3.38 | 1999- UDFA -COL | premium | premium | premium | MLB | 2006-2013 | 2002-2025 | 2006 |
| 45 | Mike Venafro | 32 | L | 1 | 0 | 2.45 | 7 | 0 | 0 | 0 | 7 | 0 | 0 | 3.2 | 3 | 1 | 1 | 0 | 3 | 2 | 0 | 0 | 0 | 1.64 | 7.36 | 0.00 | 7.36 | 4.91 | 2.45 | 0.67 | 1995- 29- 794-TEX | premium | premium | premium | MLB | 1999-2006 | 1992-2007 | 2006 |
| 50 | David Cortes | 32 | R | 3 | 1 | 4.30 | 30 | 0 | 0 | 0 | 30 | 16 | 0 | 29.1 | 35 | 14 | 14 | 3 | 6 | 14 | 0 | 0 | 1 | 1.40 | 10.74 | 0.92 | 1.84 | 4.30 | 4.30 | 2.33 | 1996- UDFA -ATL | premium | premium | premium | MLB | 1999-2006 | 1996-2010 | 2006 |
| 41 | Jeremy Affeldt | 27 | L | 4 | 2 | 6.91 | 27 | 0 | 0 | 0 | 27 | 9 | 1 | 27.1 | 31 | 23 | 21 | 4 | 13 | 20 | 0 | 0 | 1 | 1.61 | 10.21 | 1.32 | 4.28 | 6.59 | 7.57 | 1.54 | 1997- 3- 91-KCA | premium | premium | premium | MLB | 2002-2015 | 1997-2015 | 2006 |
| 47 | Scott Dohmann | 28 | R | 1 | 1 | 6.20 | 27 | 0 | 0 | 0 | 27 | 9 | 1 | 24.2 | 26 | 18 | 17 | 4 | 15 | 22 | 2 | 0 | 2 | 1.66 | 9.49 | 1.46 | 5.47 | 8.03 | 6.57 | 1.47 | 2000- 6- 167-COL | premium | premium | premium | MLB | 2004-2008 | 1999-2011 | 2006 |
| 28 | Aaron Cook | 27 | R | 9 | 15 | 4.23 | 32 | 32 | 0 | 0 | 0 | 0 | 0 | 212.2 | 242 | 107 | 100 | 17 | 55 | 92 | 2 | 0 | 7 | 1.40 | 10.24 | 0.72 | 2.33 | 3.89 | 4.53 | 1.67 | 1997- 2- 70-COL | premium | premium | premium | MLB | 2002-2012 | 1997-2013 | 2006 |
| 32 | Jason Jennings | 27 | R | 9 | 13 | 3.78 | 32 | 32 | 3 | 2 | 0 | 0 | 0 | 212.0 | 206 | 94 | 89 | 17 | 85 | 142 | 10 | 0 | 3 | 1.37 | 8.75 | 0.72 | 3.61 | 6.03 | 3.99 | 1.67 | 1999- 1- 16-COL | premium | premium | premium | MLB | 2001-2009 | 1997-2011 | 2006 |
| 26 | Jeff Francis | 25 | L | 13 | 11 | 4.16 | 32 | 32 | 1 | 1 | 0 | 0 | 0 | 199.0 | 187 | 101 | 92 | 18 | 69 | 117 | 0 | 0 | 13 | 1.29 | 8.46 | 0.81 | 3.12 | 5.29 | 4.57 | 1.70 | 2002- 1- 9-COL | premium | premium | premium | MLB | 2004-2015 | 2002-2015 | 2006 |
| 37 | Josh Fogg | 29 | R | 11 | 9 | 5.49 | 31 | 31 | 1 | 1 | 0 | 0 | 0 | 172.0 | 206 | 115 | 105 | 24 | 60 | 93 | 3 | 0 | 6 | 1.55 | 10.78 | 1.26 | 3.14 | 4.87 | 6.02 | 1.55 | 1998- 3- 89-CHA | premium | premium | premium | MLB | 2001-2009 | 1996-2010 | 2006 |
| 49 | Byung-Hyun Kim | 27 | R | 8 | 12 | 5.57 | 27 | 27 | 0 | 0 | 0 | 0 | 0 | 155.0 | 179 | 103 | 96 | 18 | 61 | 129 | 5 | 1 | 8 | 1.55 | 10.39 | 1.05 | 3.54 | 7.49 | 5.98 | 2.11 | 1999- UDFA -ARI | premium | premium | premium | MLB | 1999-2007 | 1999-2010 | 2006 |
| 45 | Zach Day | 28 | R | 1 | 2 | 10.80 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 13.1 | 22 | 17 | 16 | 3 | 10 | 6 | 0 | 0 | 1 | 2.40 | 14.85 | 2.03 | 6.75 | 4.05 | 11.48 | 0.60 | 1996- 5- 149-NYA | premium | premium | premium | MLB | 2002-2006 | 1996-2008 | 2006 |
| 47 | Justin Hampson | 26 | L | 1 | 0 | 7.50 | 5 | 1 | 0 | 0 | 4 | 0 | 0 | 12.0 | 19 | 10 | 10 | 3 | 5 | 9 | 1 | 0 | 1 | 2.00 | 14.25 | 2.25 | 3.75 | 6.75 | 7.50 | 1.80 | 1999- 28- 850-COL | premium | premium | premium | MLB | 2006-2012 | 2000-2013 | 2006 |
| 18 | Mike DeJean | 35 | R | 1 | 0 | 0.00 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 1.2 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 1.80 | 5.40 | 0.00 | 10.80 | 0.00 | 0.00 | 0.00 | 1992- 24- 662-NYA | premium | premium | premium | MLB | 1997-2006 | 1992-2008 | 2006 |
| Totals: | 76 | 86 | 4.66 | 661 | 162 | 5 | 4 | 157 | 499 | 34 | 1447.1 | 1549 | 812 | 749 | 155 | 553 | 952 | 43 | 2 | 55 | 1.45 | 9.63 | 0.96 | 3.44 | 5.92 | 5.05 | 1.72 | premium | premium | premium |