| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 3 | Jeromy Burnitz | 36 | RF | L | 100 | 160 | 605 | 84 | 156 | 31 | 2 | 24 | 87 | 5 | 4 | 57 | 109 | 3 | 1 | 5 | 3 | 12 | 263 | 671 | 57 | 99 | .258 | .322 | .435 | .757 | .273 | .177 | .277 | 8.49 | 16.24 | 1.91 | 25.21 | 1990- 1- 17-NYN | premium | premium | premium | MLB | 1993-2006 | 1988-2006 | 2005 |
| 25 | Derrek Lee | 29 | 1B | R | 138 | 158 | 594 | 120 | 199 | 50 | 3 | 46 | 107 | 15 | 3 | 85 | 109 | 5 | 0 | 7 | 23 | 12 | 393 | 691 | 99 | 100 | .335 | .418 | .662 | 1.080 | .490 | .327 | .343 | 12.30 | 15.77 | 1.28 | 12.91 | 1993- 1- 14-SDN | premium | premium | premium | MLB | 1997-2011 | 1993-2011 | 2005 |
| 13 | Neifi Perez | 32 | SS | B | 90 | 154 | 572 | 59 | 157 | 33 | 1 | 9 | 54 | 8 | 4 | 18 | 47 | 3 | 12 | 4 | 3 | 22 | 219 | 609 | 43 | 114 | .274 | .298 | .383 | .681 | .147 | .109 | .285 | 2.96 | 7.72 | 2.61 | 63.56 | 1992- UDFA -COL | premium | premium | premium | MLB | 1996-2007 | 1993-2007 | 2005 |
| 16 | Aramis Ramirez | 27 | 3B | R | 121 | 123 | 463 | 72 | 140 | 30 | 0 | 31 | 92 | 0 | 1 | 35 | 60 | 6 | 0 | 2 | 4 | 15 | 263 | 506 | 61 | 79 | .302 | .358 | .568 | .926 | .339 | .266 | .291 | 6.92 | 11.86 | 1.71 | 14.94 | 1994- UDFA -PIT | premium | premium | premium | MLB | 1998-2015 | 1996-2015 | 2005 |
| 20 | Corey Patterson | 25 | CF | L | 81 | 126 | 451 | 47 | 97 | 15 | 3 | 13 | 34 | 15 | 5 | 23 | 118 | 1 | 5 | 1 | 3 | 5 | 157 | 481 | 31 | 66 | .215 | .254 | .348 | .602 | .206 | .133 | .262 | 4.78 | 24.53 | 5.13 | 34.69 | 1998- 1- 3-CHN | premium | premium | premium | MLB | 2000-2011 | 1999-2013 | 2005 |
| 8 | Michael Barrett | 28 | C | R | 108 | 133 | 424 | 48 | 117 | 32 | 3 | 16 | 61 | 0 | 3 | 40 | 61 | 7 | 2 | 4 | 3 | 7 | 203 | 477 | 51 | 66 | .276 | .345 | .479 | .824 | .290 | .203 | .288 | 8.39 | 12.79 | 1.53 | 26.50 | 1995- 1- 28-MON | premium | premium | premium | MLB | 1998-2009 | 1995-2010 | 2005 |
| 7 | Todd Walker | 32 | 2B | L | 110 | 110 | 397 | 50 | 121 | 25 | 3 | 12 | 40 | 1 | 1 | 31 | 40 | 1 | 2 | 2 | 1 | 8 | 188 | 433 | 40 | 81 | .305 | .355 | .474 | .829 | .247 | .169 | .314 | 7.16 | 9.24 | 1.29 | 33.08 | 1994- 1- 8-MIN | premium | premium | premium | MLB | 1996-2007 | 1992-2007 | 2005 |
| 15 | Jerry Hairston | 29 | CF-2B | R | 95 | 114 | 380 | 51 | 99 | 25 | 2 | 4 | 30 | 8 | 9 | 31 | 46 | 12 | 7 | 0 | 0 | 5 | 140 | 430 | 31 | 68 | .261 | .336 | .368 | .704 | .187 | .107 | .288 | 7.21 | 10.70 | 1.48 | 95.00 | 1997- 11- 345-BAL | premium | premium | premium | MLB | 1998-2013 | 1996-2013 | 2005 |
| 28 | Todd Hollandsworth | 32 | LF | L | 89 | 107 | 268 | 23 | 68 | 17 | 2 | 5 | 35 | 4 | 4 | 18 | 53 | 1 | 1 | 2 | 1 | 4 | 104 | 290 | 24 | 44 | .254 | .301 | .388 | .689 | .201 | .134 | .297 | 6.21 | 18.28 | 2.94 | 53.60 | 1991- 3- 80-LAN | premium | premium | premium | MLB | 1995-2006 | 1991-2006 | 2005 |
| 5 | Nomar Garciaparra | 31 | 3B-SS | R | 102 | 62 | 230 | 28 | 65 | 12 | 0 | 9 | 30 | 0 | 0 | 12 | 24 | 2 | 0 | 3 | 0 | 6 | 104 | 247 | 21 | 44 | .283 | .320 | .452 | .772 | .222 | .169 | .280 | 4.86 | 9.72 | 2.00 | 25.56 | 1994- 1- 12-BOS | premium | premium | premium | MLB | 1996-2009 | 1992-2009 | 2005 |
| 1 | Jose Macias | 33 | 3B-2B | B | 79* | 112 | 177 | 15 | 45 | 8 | 0 | 1 | 13 | 4 | 3 | 6 | 24 | 0 | 4 | 3 | 0 | 6 | 56 | 190 | 9 | 36 | .254 | .274 | .316 | .590 | .102 | .062 | .284 | 3.16 | 12.63 | 4.00 | 177.00 | 1992- UDFA -MON | premium | premium | premium | MLB | 1999-2005 | 1994-2010 | 2005 |
| 9,24 | Henry Blanco | 33 | C | R | 90* | 54 | 161 | 16 | 39 | 6 | 0 | 6 | 25 | 0 | 0 | 11 | 24 | 0 | 4 | 2 | 1 | 6 | 63 | 178 | 12 | 27 | .242 | .287 | .391 | .678 | .217 | .149 | .248 | 6.18 | 13.48 | 2.18 | 26.83 | 1989- UDFA -LAN | premium | premium | premium | MLB | 1997-2013 | 1990-2013 | 2005 |
| 4 | Jason Dubois | 26 | LF | R | 97 | 52 | 142 | 15 | 34 | 12 | 0 | 7 | 22 | 0 | 1 | 7 | 49 | 3 | 0 | 0 | 1 | 3 | 67 | 152 | 19 | 15 | .239 | .289 | .472 | .761 | .275 | .233 | .314 | 4.61 | 32.24 | 7.00 | 20.29 | 2000- 14- 403-CHN | premium | premium | premium | MLB | 2004-2005 | 1999-2010 | 2005 |
| 19 | Matt Murton | 23 | LF | R | 117* | 51 | 140 | 19 | 45 | 3 | 2 | 7 | 14 | 2 | 1 | 16 | 22 | 0 | 2 | 2 | 4 | 4 | 73 | 160 | 12 | 33 | .321 | .386 | .521 | .907 | .321 | .200 | .336 | 10.00 | 13.75 | 1.38 | 20.00 | 2003- 1- 32-BOS | premium | premium | premium | MLB | 2005-2009 | 2001-2017 | 2005 |
| 38 | Carlos Zambrano | 24 | P | B | 34 | 80 | 8 | 24 | 6 | 2 | 1 | 6 | 0 | 0 | 0 | 25 | 0 | 4 | 0 | 0 | 2 | 37 | 84 | 9 | 15 | .300 | .300 | .463 | .763 | .163 | .163 | .426 | 0.00 | 29.76 | 0.00 | 80.00 | 1997- UDFA -CHN | premium | premium | premium | MLB | 2001-2012 | 1998-2019 | 2005 | |
| 11 | Ronny Cedeno | 22 | SS | R | 41 | 80 | 13 | 24 | 3 | 0 | 1 | 6 | 1 | 0 | 5 | 11 | 2 | 2 | 0 | 1 | 4 | 30 | 89 | 4 | 20 | .300 | .356 | .375 | .731 | .150 | .075 | .338 | 5.62 | 12.36 | 2.20 | 80.00 | 1999- UDFA -CHN | premium | premium | premium | MLB | 2005-2014 | 2001-2015 | 2005 | |
| 50 | Matt Lawton | 33 | LF | L | 103 | 19 | 78 | 8 | 19 | 2 | 0 | 1 | 5 | 1 | 0 | 4 | 8 | 1 | 0 | 0 | 0 | 3 | 24 | 83 | 3 | 16 | .244 | .289 | .308 | .597 | .128 | .064 | .261 | 4.82 | 9.64 | 2.00 | 78.00 | 1991- 13- 336-MIN | premium | premium | premium | MLB | 1995-2006 | 1992-2006 | 2005 |
| 31 | Greg Maddux | 39 | P | R | 35 | 76 | 4 | 13 | 0 | 0 | 1 | 5 | 1 | 0 | 0 | 15 | 0 | 7 | 0 | 0 | 4 | 16 | 83 | 1 | 12 | .171 | .171 | .211 | .382 | .053 | .040 | .200 | 0.00 | 18.07 | 0.00 | 76.00 | 1984- 2- 31-CHN | premium | premium | premium | MLB | 1986-2008 | 1984-2008 | 2005 | |
| 22 | Mark Prior | 24 | P | R | 27 | 48 | 5 | 11 | 2 | 0 | 0 | 3 | 0 | 0 | 2 | 14 | 0 | 6 | 0 | 0 | 0 | 13 | 56 | 2 | 9 | .229 | .260 | .271 | .531 | .083 | .042 | .324 | 3.57 | 25.00 | 7.00 | 0.00 | 2001- 1- 2-CHN | premium | premium | premium | MLB | 2002-2006 | 1999-2013 | 2005 | |
| 33 | Glendon Rusch | 30 | P | L | 46 | 41 | 2 | 6 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 9 | 1 | 0 | 0 | 0 | 2 | 8 | 43 | 2 | 4 | .146 | .186 | .195 | .381 | .073 | .049 | .188 | 2.33 | 20.93 | 9.00 | 0.00 | 1993- 17- 469-KCA | premium | premium | premium | MLB | 1997-2009 | 1993-2009 | 2005 | |
| 32 | Jerome Williams | 23 | P | R | 18 | 30 | 1 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 16 | 0 | 6 | 0 | 0 | 0 | 4 | 36 | 1 | 2 | .100 | .100 | .133 | .233 | .033 | .033 | .214 | 0.00 | 44.44 | 0.00 | 0.00 | 1999- 1- 39-SFN | premium | premium | premium | MLB | 2003-2016 | 1999-2018 | 2005 | |
| 19 | Enrique Wilson | 31 | 2B-SS | B | 15 | 22 | 1 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 5 | 25 | 2 | 1 | .136 | .240 | .227 | .467 | .227 | .091 | .143 | 12.00 | 4.00 | 0.33 | 0.00 | 1992- UDFA -MIN | premium | premium | premium | MLB | 1997-2005 | 1992-2006 | 2005 | |
| 4 | Ben Grieve | 29 | LF | L | 23 | 20 | 1 | 5 | 0 | 0 | 0 | 1 | 0 | 0 | 5 | 7 | 0 | 0 | 0 | 1 | 0 | 5 | 25 | 0 | 5 | .250 | .400 | .250 | .650 | .250 | .000 | .385 | 20.00 | 28.00 | 1.40 | 0.00 | 1994- 1- 2-OAK | premium | premium | premium | MLB | 1997-2005 | 1994-2005 | 2005 | |
| 34 | Kerry Wood | 28 | P | R | 21 | 18 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 0 | 1 | 6 | 0 | 2 | 0 | 0 | 0 | 4 | 21 | 2 | 0 | .111 | .158 | .222 | .380 | .167 | .111 | .167 | 4.76 | 28.57 | 6.00 | 0.00 | 1995- 1- 4-CHN | premium | premium | premium | MLB | 1998-2012 | 1995-2012 | 2005 | |
| 46 | Ryan Dempster | 28 | P | R | 63 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 14 | 0 | 1 | .071 | .071 | .071 | .142 | .000 | .000 | .111 | 0.00 | 35.71 | 0.00 | 0.00 | 1995- 3- 66-TEX | premium | premium | premium | MLB | 1998-2013 | 1995-2013 | 2005 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 29 | Jody Gerut | 27 | LF | L | 92* | 11 | 14 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 2 | 16 | 1 | 0 | .071 | .188 | .143 | .331 | .214 | .072 | .091 | 12.50 | 18.75 | 1.50 | 0.00 | 1998- 2- 71-COL | premium | premium | premium | MLB | 2003-2010 | 1996-2010 | 2005 |
| 9 | Scott McClain | 33 | 1B-3B | R | 13 | 14 | 1 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 1 | 3 | 16 | 1 | 1 | .143 | .250 | .214 | .464 | .214 | .071 | .167 | 12.50 | 12.50 | 1.00 | 0.00 | 1990- 22- 604-BAL | premium | premium | premium | MLB | 1998-2008 | 1990-2009 | 2005 | |
| 55 | Ryan Theriot | 25 | 2B | R | 9 | 13 | 3 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 3 | 14 | 1 | 1 | .154 | .214 | .231 | .445 | .154 | .077 | .182 | 7.14 | 14.29 | 2.00 | 0.00 | 2001- 3- 78-CHN | premium | premium | premium | MLB | 2005-2012 | 1999-2012 | 2005 | |
| 52 | Sergio Mitre | 24 | P | R | 21 | 11 | 2 | 4 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 5 | 12 | 1 | 3 | .364 | .364 | .455 | .819 | .091 | .091 | .400 | 0.00 | 8.33 | 0.00 | 0.00 | 2001- 7- 198-CHN | premium | premium | premium | MLB | 2003-2011 | 2001-2019 | 2005 | |
| 53 | Rich Hill | 25 | P | L | 10 | 6 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 6 | 0 | 2 | .333 | .333 | .333 | .666 | .000 | .000 | .500 | 0.00 | 33.33 | 0.00 | 0.00 | 2002- 4- 112-CHN | premium | premium | premium | MLB | 2005-2025 | 2000-2025 | 2005 | |
| 49 | John Koronka | 24 | P | L | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .200 | .000 | .200 | .250 | .000 | .000 | 20.00 | 60.00 | 3.00 | 0.00 | 1998- 12- 350-CIN | premium | premium | premium | MLB | 2005-2009 | 1998-2011 | 2005 | |
| 40 | Todd Wellemeyer | 26 | P | R | 22 | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .250 | .250 | .250 | .500 | .000 | .000 | .500 | 0.00 | 50.00 | 0.00 | 0.00 | 2000- 4- 103-CHN | premium | premium | premium | MLB | 2003-2010 | 2000-2011 | 2005 | |
| 29 | Mike Fontenot | 25 | 2B | L | 7 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .600 | .000 | .600 | 1.000 | .000 | .000 | 40.00 | 0.00 | 0.00 | 0.00 | 2001- 1- 19-BAL | premium | premium | premium | MLB | 2005-2012 | 2000-2014 | 2005 | |
| 43 | Michael Wuertz | 26 | P | R | 75 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1997- 11- 334-CHN | premium | premium | premium | MLB | 2004-2011 | 1998-2014 | 2005 | |
| 58 | Geovany Soto | 22 | C | R | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2001- 11- 318-CHN | premium | premium | premium | MLB | 2005-2017 | 2001-2017 | 2005 | |
| 44 | Roberto Novoa | 25 | P | R | 49 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1999- UDFA -PIT | premium | premium | premium | MLB | 2004-2006 | 2001-2014 | 2005 | |
| 56 | Cliff Bartosh | 25 | P | L | 19 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1.000 | 1.000 | 1.000 | 2.000 | .000 | .000 | 1.000 | 0.00 | 0.00 | 0.00 | 0.00 | 1998- 29- 862-SDN | premium | premium | premium | MLB | 2004-2005 | 1998-2005 | 2005 | |
| 51 | Jon Leicester | 26 | P | R | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2000- 11- 313-CHN | premium | premium | premium | MLB | 2004-2007 | 1998-2016 | 2005 | |
| 17 | Adam Greenberg | 24 | OF | L | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | 1.000 | .000 | 1.000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2002- 9- 273-CHN | premium | premium | premium | MLB | 2005-2012 | 2000-2013 | 2005 | |
| Totals: | 2106 | 5584 | 703 | 1506 | 323 | 23 | 194 | 674 | 65 | 39 | 419 | 920 | 50 | 69 | 37 | 49 | 131 | 2457 | 6159 | 540 | 966 | .270 | .324 | .440 | .764 | .250 | .170 | .291 | 6.80 | 14.94 | 2.20 | 28.78 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 46 | Ryan Dempster | 28 | R | 5 | 3 | 3.13 | 63 | 6 | 0 | 0 | 57 | 53 | 33 | 92.0 | 83 | 35 | 32 | 4 | 49 | 89 | 4 | 0 | 4 | 1.43 | 8.12 | 0.39 | 4.79 | 8.71 | 3.42 | 1.82 | 1995- 3- 66-TEX | premium | premium | premium | MLB | 1998-2013 | 1995-2013 | 2005 |
| 51 | Jon Leicester | 26 | R | 0 | 2 | 9.00 | 6 | 1 | 0 | 0 | 5 | 2 | 0 | 9.0 | 11 | 10 | 9 | 2 | 9 | 7 | 1 | 0 | 2 | 2.22 | 11.00 | 2.00 | 9.00 | 7.00 | 10.00 | 0.78 | 2000- 11- 313-CHN | premium | premium | premium | MLB | 2004-2007 | 1998-2016 | 2005 |
| 47 | Chad Fox | 34 | R | 0 | 0 | 6.75 | 11 | 0 | 0 | 0 | 11 | 4 | 1 | 8.0 | 8 | 6 | 6 | 2 | 8 | 11 | 0 | 0 | 0 | 2.00 | 9.00 | 2.25 | 9.00 | 12.38 | 6.75 | 1.38 | 1992- 23- 633-CIN | premium | premium | premium | MLB | 1997-2009 | 1992-2009 | 2005 |
| 43 | Michael Wuertz | 26 | R | 6 | 2 | 3.81 | 75 | 0 | 0 | 0 | 75 | 12 | 0 | 75.2 | 60 | 36 | 32 | 6 | 40 | 89 | 7 | 0 | 0 | 1.32 | 7.14 | 0.71 | 4.76 | 10.59 | 4.28 | 2.23 | 1997- 11- 334-CHN | premium | premium | premium | MLB | 2004-2011 | 1998-2014 | 2005 |
| 34 | Kerry Wood | 28 | R | 3 | 4 | 4.23 | 21 | 10 | 0 | 0 | 11 | 4 | 0 | 66.0 | 52 | 32 | 31 | 14 | 26 | 77 | 0 | 0 | 2 | 1.18 | 7.09 | 1.91 | 3.55 | 10.50 | 4.36 | 2.96 | 1995- 1- 4-CHN | premium | premium | premium | MLB | 1998-2012 | 1995-2012 | 2005 |
| 52 | Sergio Mitre | 24 | R | 2 | 5 | 5.37 | 21 | 7 | 1 | 1 | 14 | 7 | 0 | 60.1 | 62 | 37 | 36 | 11 | 23 | 37 | 5 | 0 | 3 | 1.41 | 9.25 | 1.64 | 3.43 | 5.52 | 5.52 | 1.61 | 2001- 7- 198-CHN | premium | premium | premium | MLB | 2003-2011 | 2001-2019 | 2005 |
| 37 | Jermaine Van Buren | 24 | R | 0 | 2 | 3.00 | 6 | 0 | 0 | 0 | 6 | 1 | 0 | 6.0 | 2 | 2 | 2 | 0 | 9 | 3 | 0 | 0 | 0 | 1.83 | 3.00 | 0.00 | 13.50 | 4.50 | 3.00 | 0.33 | 1998- 2- 60-COL | premium | premium | premium | MLB | 2005-2006 | 1998-2010 | 2005 |
| 44 | Roberto Novoa | 25 | R | 4 | 5 | 4.43 | 49 | 0 | 0 | 0 | 49 | 11 | 0 | 44.2 | 47 | 22 | 22 | 4 | 25 | 47 | 4 | 1 | 0 | 1.61 | 9.47 | 0.81 | 5.04 | 9.47 | 4.43 | 1.88 | 1999- UDFA -PIT | premium | premium | premium | MLB | 2004-2006 | 2001-2014 | 2005 |
| 45,50 | Will Ohman | 27 | L | 2 | 2 | 2.91 | 69 | 0 | 0 | 0 | 69 | 13 | 0 | 43.1 | 32 | 14 | 14 | 6 | 24 | 45 | 6 | 1 | 3 | 1.29 | 6.65 | 1.25 | 4.98 | 9.35 | 2.91 | 1.88 | 1998- 8- 226-CHN | premium | premium | premium | MLB | 2000-2012 | 1998-2012 | 2005 |
| 37 | Mike Remlinger | 39 | L | 0 | 3 | 4.91 | 35 | 0 | 0 | 0 | 35 | 7 | 0 | 33.0 | 31 | 19 | 18 | 5 | 12 | 30 | 0 | 0 | 2 | 1.30 | 8.45 | 1.36 | 3.27 | 8.18 | 5.18 | 2.50 | 1987- 1- 16-SFN | premium | premium | premium | MLB | 1991-2006 | 1987-2006 | 2005 |
| 40 | Todd Wellemeyer | 26 | R | 2 | 1 | 6.12 | 22 | 0 | 0 | 0 | 22 | 6 | 1 | 32.1 | 32 | 23 | 22 | 7 | 22 | 32 | 3 | 0 | 0 | 1.67 | 8.91 | 1.95 | 6.12 | 8.91 | 6.40 | 1.45 | 2000- 4- 103-CHN | premium | premium | premium | MLB | 2003-2010 | 2000-2011 | 2005 |
| 53 | Rich Hill | 25 | L | 0 | 2 | 9.13 | 10 | 4 | 0 | 0 | 6 | 1 | 0 | 23.2 | 25 | 24 | 24 | 3 | 17 | 21 | 0 | 0 | 1 | 1.77 | 9.51 | 1.14 | 6.46 | 7.99 | 9.13 | 1.24 | 2002- 4- 112-CHN | premium | premium | premium | MLB | 2005-2025 | 2000-2025 | 2005 |
| 31 | Greg Maddux | 39 | R | 13 | 15 | 4.24 | 35 | 35 | 3 | 0 | 0 | 0 | 0 | 225.0 | 239 | 112 | 106 | 29 | 36 | 136 | 8 | 0 | 7 | 1.22 | 9.56 | 1.16 | 1.44 | 5.44 | 4.48 | 3.78 | 1984- 2- 31-CHN | premium | premium | premium | MLB | 1986-2008 | 1984-2008 | 2005 |
| 38 | Carlos Zambrano | 24 | R | 14 | 6 | 3.26 | 33 | 33 | 2 | 0 | 0 | 0 | 0 | 223.1 | 170 | 88 | 81 | 21 | 86 | 202 | 7 | 0 | 8 | 1.15 | 6.85 | 0.85 | 3.47 | 8.14 | 3.55 | 2.35 | 1997- UDFA -CHN | premium | premium | premium | MLB | 2001-2012 | 1998-2019 | 2005 |
| 56 | Cliff Bartosh | 25 | L | 0 | 2 | 5.49 | 19 | 0 | 0 | 0 | 19 | 7 | 0 | 19.2 | 23 | 13 | 12 | 7 | 11 | 15 | 0 | 0 | 2 | 1.73 | 10.53 | 3.20 | 5.03 | 6.86 | 5.95 | 1.36 | 1998- 29- 862-SDN | premium | premium | premium | MLB | 2004-2005 | 1998-2005 | 2005 |
| 32 | LaTroy Hawkins | 32 | R | 1 | 4 | 3.32 | 21 | 0 | 0 | 0 | 21 | 12 | 4 | 19.0 | 18 | 9 | 7 | 4 | 7 | 13 | 0 | 0 | 0 | 1.32 | 8.53 | 1.89 | 3.32 | 6.16 | 4.26 | 1.86 | 1991- 7- 180-MIN | premium | premium | premium | MLB | 1995-2015 | 1991-2015 | 2005 |
| 22 | Mark Prior | 24 | R | 11 | 7 | 3.67 | 27 | 27 | 1 | 0 | 0 | 0 | 0 | 166.2 | 143 | 73 | 68 | 25 | 59 | 188 | 4 | 1 | 4 | 1.21 | 7.72 | 1.35 | 3.19 | 10.15 | 3.94 | 3.19 | 2001- 1- 2-CHN | premium | premium | premium | MLB | 2002-2006 | 1999-2013 | 2005 |
| 49 | John Koronka | 24 | L | 1 | 2 | 7.47 | 4 | 3 | 0 | 0 | 1 | 1 | 0 | 15.2 | 19 | 13 | 13 | 2 | 8 | 10 | 1 | 2 | 0 | 1.72 | 10.91 | 1.15 | 4.60 | 5.74 | 7.47 | 1.25 | 1998- 12- 350-CIN | premium | premium | premium | MLB | 2005-2009 | 1998-2011 | 2005 |
| 33 | Glendon Rusch | 30 | L | 9 | 8 | 4.52 | 46 | 19 | 1 | 1 | 27 | 6 | 0 | 145.1 | 175 | 79 | 73 | 14 | 53 | 111 | 1 | 1 | 1 | 1.57 | 10.84 | 0.87 | 3.28 | 6.87 | 4.89 | 2.09 | 1993- 17- 469-KCA | premium | premium | premium | MLB | 1997-2009 | 1993-2009 | 2005 |
| 48 | Scott Williamson | 29 | R | 0 | 0 | 5.65 | 17 | 0 | 0 | 0 | 17 | 4 | 0 | 14.1 | 15 | 9 | 9 | 3 | 6 | 23 | 4 | 1 | 2 | 1.47 | 9.42 | 1.88 | 3.77 | 14.44 | 5.65 | 3.83 | 1997- 9- 278-CIN | premium | premium | premium | MLB | 1999-2007 | 1995-2011 | 2005 |
| 48 | Joe Borowski | 34 | R | 0 | 0 | 6.55 | 11 | 0 | 0 | 0 | 11 | 3 | 0 | 11.0 | 12 | 8 | 8 | 5 | 1 | 11 | 0 | 0 | 0 | 1.18 | 9.82 | 4.09 | 0.82 | 9.00 | 6.55 | 11.00 | 1989- 32- 823-CHA | premium | premium | premium | MLB | 1995-2008 | 1990-2008 | 2005 |
| 32 | Jerome Williams | 23 | R | 6 | 8 | 3.91 | 18 | 17 | 0 | 0 | 1 | 0 | 0 | 106.0 | 98 | 50 | 46 | 12 | 45 | 59 | 2 | 0 | 9 | 1.35 | 8.32 | 1.02 | 3.82 | 5.01 | 4.25 | 1.31 | 1999- 1- 39-SFN | premium | premium | premium | MLB | 2003-2016 | 1999-2018 | 2005 |
| Totals: | 79 | 83 | 4.19 | 619 | 162 | 8 | 2 | 154 | 457 | 39 | 1440.0 | 1357 | 714 | 671 | 186 | 576 | 1256 | 57 | 7 | 50 | 1.34 | 8.48 | 1.16 | 3.60 | 7.85 | 4.46 | 2.18 | premium | premium | premium |