| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 3 | Josh Anderson | 22 | OF | L | 94 | 127 | 524 | 67 | 148 | 17 | 9 | 1 | 26 | 50 | 19 | 29 | 80 | 8 | 10 | 2 | 2 | 5 | 186 | 573 | 27 | 121 | .282 | .329 | .355 | .684 | .187 | .073 | .330 | 5.06 | 13.96 | 2.76 | 524.00 | 2003- 4- 119-HOU | premium | premium | premium | MLB | 2007-2009 | 2001-2010 | 2005 |
| 8 | Mark Saccomanno | 25 | 3B-1B | R | 99 | 134 | 514 | 66 | 143 | 36 | 1 | 12 | 51 | 5 | 3 | 27 | 108 | 4 | 0 | 1 | 1 | 11 | 217 | 546 | 49 | 94 | .278 | .319 | .422 | .741 | .200 | .144 | .332 | 4.95 | 19.78 | 4.00 | 42.83 | 2003- 23- 689-HOU | premium | premium | premium | MLB | 2008-2008 | 1999-2010 | 2005 |
| 18 | Hector Gimenez | 22 | C | B | 96 | 121 | 454 | 47 | 124 | 19 | 1 | 12 | 58 | 2 | 3 | 32 | 88 | 2 | 7 | 3 | 2 | 8 | 181 | 498 | 32 | 92 | .273 | .322 | .399 | .721 | .194 | .126 | .314 | 6.43 | 17.67 | 2.75 | 37.83 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2006-2013 | 2002-2016 | 2005 |
| 4 | Eric Riggs | 28 | 2B-SS | B | 96 | 130 | 452 | 40 | 118 | 27 | 3 | 7 | 57 | 5 | 7 | 52 | 77 | 4 | 8 | 8 | 2 | 11 | 172 | 524 | 37 | 81 | .261 | .337 | .381 | .718 | .230 | .120 | .295 | 9.92 | 14.69 | 1.48 | 64.57 | 1998- 4- 126-LAN | premium | premium | premium | AAA | 1996-2007 | 2005 | |
| - | Charlton Jimerson | 25 | OF | R | 101 | 115 | 425 | 67 | 110 | 24 | 3 | 16 | 44 | 27 | 10 | 29 | 145 | 8 | 3 | 2 | 4 | 0 | 188 | 467 | 43 | 67 | .259 | .317 | .442 | .759 | .292 | .183 | .353 | 6.21 | 31.05 | 5.00 | 26.56 | 2001- 5- 146-HOU | premium | premium | premium | MLB | 2006-2008 | 1998-2010 | 2005 |
| 9 | Mike Rodriguez | 24 | OF | L | 104 | 116 | 392 | 51 | 110 | 16 | 9 | 5 | 50 | 25 | 7 | 47 | 50 | 4 | 7 | 6 | 3 | 4 | 159 | 456 | 30 | 80 | .281 | .359 | .406 | .765 | .291 | .125 | .306 | 10.31 | 10.96 | 1.06 | 78.40 | 2001- 2- 54-HOU | premium | premium | premium | AAA | 1999-2009 | 2005 | |
| 10 | Dax Norris | 33 | C | R | 87 | 106 | 355 | 28 | 79 | 16 | 0 | 13 | 50 | 0 | 1 | 27 | 42 | 0 | 0 | 5 | 1 | 13 | 134 | 387 | 29 | 50 | .223 | .274 | .377 | .651 | .228 | .154 | .216 | 6.98 | 10.85 | 1.56 | 27.31 | 1996- 23- 692-ATL | premium | premium | premium | AAA | 1995-2006 | 2005 | |
| 40 | Carlos Rodriguez | 21 | OF | B | 85 | 88 | 318 | 30 | 78 | 12 | 1 | 9 | 42 | 3 | 4 | 8 | 71 | 2 | 0 | 1 | 0 | 9 | 119 | 329 | 22 | 56 | .245 | .267 | .374 | .641 | .151 | .129 | .289 | 2.43 | 21.58 | 8.88 | 35.33 | premium | premium | premium | AA | 2001-2005 | 2005 | ||
| 17 | Wade Robinson | 24 | SS | L | 77 | 69 | 219 | 19 | 53 | 4 | 0 | 1 | 16 | 8 | 10 | 20 | 51 | 0 | 10 | 3 | 0 | 4 | 60 | 252 | 5 | 48 | .242 | .302 | .274 | .576 | .114 | .032 | .306 | 7.94 | 20.24 | 2.55 | 219.00 | 2003- 12- 359-HOU | premium | premium | premium | AAA | 2000-2008 | 2005 | |
| - | Ray Navarrete | 27 | 2B-3B | R | 86 | 52 | 194 | 23 | 45 | 12 | 0 | 5 | 16 | 1 | 3 | 7 | 30 | 5 | 1 | 1 | 0 | 5 | 72 | 208 | 17 | 28 | .232 | .275 | .371 | .646 | .165 | .139 | .250 | 3.37 | 14.42 | 4.29 | 38.80 | premium | premium | premium | AAA | 1997-2013 | 2005 | ||
| 25 | John Fagan | 25 | OF | R | 99 | 68 | 173 | 18 | 44 | 4 | 1 | 3 | 15 | 4 | 0 | 22 | 50 | 7 | 0 | 0 | 1 | 1 | 59 | 202 | 8 | 36 | .254 | .361 | .341 | .702 | .237 | .087 | .342 | 10.89 | 24.75 | 2.27 | 57.67 | 2001- 33- 986-HOU | premium | premium | premium | AA | 2000-2006 | 2005 | |
| 45 | J.R. Phillips | 35 | 1B | L | 111 | 43 | 156 | 20 | 46 | 5 | 0 | 8 | 20 | 2 | 2 | 21 | 42 | 0 | 0 | 3 | 3 | 2 | 75 | 180 | 13 | 33 | .295 | .372 | .481 | .853 | .321 | .186 | .349 | 11.67 | 23.33 | 2.00 | 19.50 | 1988- 4- 91-CAL | premium | premium | premium | MLB | 1993-1999 | 1988-2005 | 2005 |
| - | Tommy Whiteman | 25 | SS-3B | R | 90 | 41 | 152 | 13 | 38 | 9 | 0 | 1 | 15 | 3 | 4 | 18 | 40 | 1 | 2 | 0 | 0 | 4 | 50 | 173 | 10 | 28 | .250 | .333 | .329 | .662 | .191 | .079 | .333 | 10.40 | 23.12 | 2.22 | 152.00 | 2000- 6- 187-HOU | premium | premium | premium | AAA | 1999-2006 | 2005 | |
| - | Junior Zamora | 29 | 3B-1B | R | 69* | 45 | 126 | 10 | 25 | 7 | 0 | 0 | 4 | 0 | 0 | 5 | 31 | 3 | 0 | 0 | 0 | 6 | 32 | 134 | 7 | 18 | .198 | .246 | .254 | .500 | .095 | .056 | .263 | 3.73 | 23.13 | 6.20 | 0.00 | premium | premium | premium | AAA | 1995-2007 | 2005 | ||
| - | Alex Eckelman | 30 | SS-3B | R | 91* | 26 | 84 | 6 | 23 | 3 | 0 | 1 | 6 | 0 | 1 | 4 | 9 | 3 | 0 | 1 | 0 | 0 | 29 | 92 | 4 | 19 | .274 | .326 | .345 | .671 | .107 | .071 | .293 | 4.35 | 9.78 | 2.25 | 84.00 | premium | premium | premium | AAA | 1994-2005 | 2005 | ||
| - | Brooks Conrad | 25 | 2B | B | 112* | 22 | 77 | 13 | 18 | 6 | 1 | 2 | 11 | 8 | 0 | 16 | 15 | 1 | 0 | 0 | 1 | 1 | 32 | 94 | 9 | 9 | .234 | .372 | .416 | .788 | .494 | .182 | .267 | 17.02 | 15.96 | 0.94 | 38.50 | 2001- 8- 236-HOU | premium | premium | premium | MLB | 2008-2014 | 1999-2016 | 2005 |
| 7 | Jason Clements | 27 | 2B | B | 15 | 43 | 5 | 13 | 3 | 1 | 0 | 7 | 0 | 0 | 1 | 7 | 0 | 0 | 0 | 0 | 0 | 18 | 44 | 4 | 9 | .302 | .318 | .419 | .737 | .140 | .117 | .361 | 2.27 | 15.91 | 7.00 | 0.00 | 1999- 19- 573-OAK | premium | premium | premium | AAA | 1999-2005 | 2005 | ||
| - | Pat Peavey | 25 | 3B | R | 12 | 31 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 3 | 8 | 2 | 2 | 0 | 0 | 1 | 2 | 38 | 0 | 2 | .065 | .194 | .065 | .259 | .097 | .000 | .087 | 7.89 | 21.05 | 2.67 | 0.00 | 2002- 33-1001-HOU | premium | premium | premium | AA | 2001-2007 | 2005 | ||
| - | Humberto Quintero | 25 | C | R | 4 | 11 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 2 | 3 | 12 | 1 | 1 | .182 | .250 | .273 | .523 | .182 | .091 | .222 | 8.33 | 16.67 | 2.00 | 0.00 | 1997- UDFA -CHA | premium | premium | premium | MLB | 2003-2014 | 1999-2016 | 2005 | |
| 32 | Chris Sampson | 27 | P | R | 11 | 10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 0 | 0 | 0 | 1 | 11 | 0 | 1 | .100 | .100 | .100 | .200 | .000 | .000 | .167 | 0.00 | 36.36 | 0.00 | 0.00 | 1999- 8- 263-HOU | premium | premium | premium | MLB | 2006-2010 | 1999-2011 | 2005 | |
| 46 | Jason Hirsh | 23 | P | R | 4 | 10 | 2 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 7 | 0 | 0 | 0 | 0 | 0 | 1 | 11 | 0 | 1 | .100 | .182 | .100 | .282 | .100 | .000 | .333 | 9.09 | 63.64 | 7.00 | 0.00 | 2003- 2- 59-HOU | premium | premium | premium | MLB | 2006-2008 | 2003-2013 | 2005 | |
| - | Gavin Wright | 26 | OF | R | 4 | 10 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 3 | 12 | 1 | 1 | .200 | .273 | .300 | .573 | .200 | .100 | .222 | 8.33 | 8.33 | 1.00 | 0.00 | 1998- 33- 992-HOU | premium | premium | premium | AA | 1999-2005 | 2005 | ||
| - | Jeff Bagwell | 37 | 1B | R | 3 | 9 | 1 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 1 | 2 | 12 | 0 | 2 | .222 | .417 | .222 | .639 | .333 | .000 | .333 | 25.00 | 25.00 | 1.00 | 0.00 | 1989- 4- 110-BOS | premium | premium | premium | MLB | 1991-2005 | 1988-2005 | 2005 | |
| 14 | Philip Barzilla | 26 | P | L | 8 | 8 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 25.00 | 0.00 | 0.00 | 2001- 4- 116-HOU | premium | premium | premium | MLB | 2006-2006 | 2000-2010 | 2005 | |
| 22 | Tim McClaskey | 29 | P | R | 4 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 25.00 | 0.00 | 0.00 | 1995- 36- 989-MIA | premium | premium | premium | AAA | 1996-2008 | 2005 | ||
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| - | Fernando Nieve | 22 | P | R | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 42.86 | 0.00 | 0.00 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2006-2010 | 2001-2018 | 2005 | |
| 12 | Mark McLemore | 24 | P | L | 4 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .250 | .000 | .250 | .333 | .000 | .000 | 20.00 | 40.00 | 2.00 | 0.00 | 2002- 4- 131-HOU | premium | premium | premium | MLB | 2007-2007 | 2000-2011 | 2005 | |
| - | Brooks Kieschnick | 33 | P | L | 2 | 3 | 1 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 5 | 0 | 2 | .667 | .600 | .667 | 1.267 | .333 | .000 | .500 | 20.00 | 0.00 | 0.00 | 0.00 | 1993- 1- 10-CHN | premium | premium | premium | MLB | 1996-2004 | 1991-2005 | 2005 | |
| - | Scott MacRae | 30 | P | R | 5 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1995- 32- 895-CIN | premium | premium | premium | MLB | 2001-2001 | 1995-2005 | 2005 | |
| 49 | Jamie Merchant | 24 | P | R | 4 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | .500 | .500 | .500 | 1.000 | .000 | .000 | .500 | 0.00 | 0.00 | 0.00 | 0.00 | 2003- 16- 479-HOU | premium | premium | premium | AA | 2000-2007 | 2005 | ||
| 20 | Fernando Rijo | 27 | P | R | 6 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | premium | premium | premium | AAA | 1998-2011 | 2005 | |||
| 39 | Peter Bauer | 26 | P | R | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .500 | .000 | .500 | 1.000 | .000 | .000 | 50.00 | 25.00 | 0.50 | 0.00 | 2000- 2- 45-TOR | premium | premium | premium | AAA | 1998-2006 | 2005 | ||
| 13 | Monte Mansfield | 24 | P | R | 10 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2000- 16- 487-HOU | premium | premium | premium | AA | 2000-2010 | 2005 | ||
| - | Kevin Hodge | 28 | P | R | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1998- 19- 559-MIN | premium | premium | premium | AAA | 1998-2005 | 2005 | ||
| - | Wandy Rodriguez | 26 | P | B | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2005-2015 | 2001-2015 | 2005 | |
| 19 | Jailen Peguero | 24 | P | R | 11 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2000- UDFA -HOU | premium | premium | premium | MLB | 2007-2008 | 2002-2021 | 2005 | |
| 48 | Danny Fatheree | 26 | C | R | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | 1.000 | .000 | 1.000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | premium | premium | premium | AAA | 1997-2005 | 2005 | |||
| 36 | Blake Allen | 23 | P | L | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2002- 8- 244-CLE | premium | premium | premium | AA | 2002-2007 | 2005 | ||
| Totals: | 1423 | 4779 | 530 | 1228 | 222 | 30 | 96 | 495 | 143 | 74 | 378 | 973 | 55 | 56 | 37 | 21 | 88 | 1798 | 5305 | 348 | 880 | .257 | .316 | .376 | .693 | .213 | .119 | .302 | 7.13 | 18.34 | 2.57 | 49.78 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| - | Fernando Nieve | 22 | R | 4 | 3 | 2.65 | 14 | 14 | 0 | 0 | 0 | 0 | 0 | 85.0 | 62 | 27 | 25 | 7 | 29 | 96 | 4 | 0 | 3 | 1.07 | 6.56 | 0.74 | 3.07 | 10.16 | 2.86 | 3.31 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2006-2010 | 2001-2018 | 2005 |
| - | Brooks Kieschnick | 33 | R | 0 | 0 | 1.08 | 5 | 0 | 0 | 0 | 5 | 1 | 0 | 8.1 | 10 | 2 | 1 | 0 | 2 | 5 | 1 | 0 | 1 | 1.44 | 10.80 | 0.00 | 2.16 | 5.40 | 2.16 | 2.50 | 1993- 1- 10-CHN | premium | premium | premium | MLB | 1996-2004 | 1991-2005 | 2005 |
| - | Brandon Backe | 27 | R | 0 | 1 | 2.25 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 8.0 | 4 | 2 | 2 | 1 | 1 | 11 | 1 | 0 | 0 | 0.63 | 4.50 | 1.13 | 1.13 | 12.38 | 2.25 | 11.00 | 1998- 18- 552-TBA | premium | premium | premium | MLB | 2002-2009 | 1998-2009 | 2005 |
| 13 | Monte Mansfield | 24 | R | 3 | 2 | 3.82 | 43 | 0 | 0 | 0 | 43 | 26 | 0 | 75.1 | 65 | 35 | 32 | 7 | 33 | 78 | 6 | 2 | 5 | 1.30 | 7.77 | 0.84 | 3.94 | 9.32 | 4.18 | 2.36 | 2000- 16- 487-HOU | premium | premium | premium | AA | 2000-2010 | 2005 | |
| 12 | Mark McLemore | 24 | L | 5 | 6 | 2.81 | 15 | 15 | 1 | 0 | 0 | 0 | 0 | 73.2 | 59 | 34 | 23 | 5 | 34 | 65 | 1 | 0 | 2 | 1.26 | 7.21 | 0.61 | 4.15 | 7.94 | 4.15 | 1.91 | 2002- 4- 131-HOU | premium | premium | premium | MLB | 2007-2007 | 2000-2011 | 2005 |
| 44 | Josh Miller | 26 | R | 0 | 1 | 7.04 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 7.2 | 9 | 6 | 6 | 1 | 1 | 5 | 0 | 0 | 0 | 1.30 | 10.57 | 1.17 | 1.17 | 5.87 | 7.04 | 5.00 | 2001- 32- 950-PHI | premium | premium | premium | AAA | 2000-2010 | 2005 | |
| 19 | Jailen Peguero | 24 | R | 2 | 2 | 2.94 | 50 | 0 | 0 | 0 | 50 | 36 | 12 | 64.1 | 62 | 25 | 21 | 3 | 25 | 63 | 3 | 0 | 4 | 1.35 | 8.67 | 0.42 | 3.50 | 8.81 | 3.50 | 2.52 | 2000- UDFA -HOU | premium | premium | premium | MLB | 2007-2008 | 2002-2021 | 2005 |
| 20 | Fernando Rijo | 27 | R | 3 | 2 | 4.40 | 34 | 2 | 0 | 0 | 32 | 10 | 1 | 61.1 | 58 | 35 | 30 | 11 | 34 | 44 | 4 | 0 | 2 | 1.50 | 8.51 | 1.61 | 4.99 | 6.46 | 5.14 | 1.29 | premium | premium | premium | AAA | 1998-2011 | 2005 | ||
| 39 | Peter Bauer | 26 | R | 3 | 4 | 3.31 | 11 | 8 | 0 | 0 | 3 | 2 | 1 | 51.2 | 46 | 25 | 19 | 5 | 9 | 39 | 3 | 0 | 1 | 1.06 | 8.01 | 0.87 | 1.57 | 6.79 | 4.35 | 4.33 | 2000- 2- 45-TOR | premium | premium | premium | AAA | 1998-2006 | 2005 | |
| 49 | Jamie Merchant | 24 | R | 3 | 3 | 4.26 | 24 | 1 | 0 | 0 | 23 | 4 | 2 | 50.2 | 43 | 25 | 24 | 7 | 21 | 46 | 0 | 0 | 2 | 1.26 | 7.64 | 1.24 | 3.73 | 8.17 | 4.44 | 2.19 | 2003- 16- 479-HOU | premium | premium | premium | AA | 2000-2007 | 2005 | |
| - | Scott MacRae | 30 | R | 3 | 3 | 2.70 | 16 | 4 | 0 | 0 | 12 | 2 | 1 | 46.2 | 51 | 19 | 14 | 2 | 9 | 29 | 3 | 0 | 0 | 1.29 | 9.84 | 0.39 | 1.74 | 5.59 | 3.66 | 3.22 | 1995- 32- 895-CIN | premium | premium | premium | MLB | 2001-2001 | 1995-2005 | 2005 |
| 36 | Blake Allen | 23 | L | 1 | 3 | 5.36 | 16 | 6 | 0 | 0 | 10 | 3 | 0 | 42.0 | 44 | 28 | 25 | 4 | 18 | 31 | 4 | 0 | 1 | 1.48 | 9.43 | 0.86 | 3.86 | 6.64 | 6.00 | 1.72 | 2002- 8- 244-CLE | premium | premium | premium | AA | 2002-2007 | 2005 | |
| 29 | Aaron Williams | 24 | R | 2 | 1 | 2.64 | 22 | 0 | 0 | 0 | 22 | 12 | 0 | 30.2 | 27 | 10 | 9 | 2 | 15 | 19 | 2 | 1 | 3 | 1.37 | 7.92 | 0.59 | 4.40 | 5.58 | 2.93 | 1.27 | premium | premium | premium | AAA | 2002-2007 | 2005 | ||
| - | Wandy Rodriguez | 26 | L | 0 | 0 | 2.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 3.1 | 3 | 1 | 1 | 0 | 2 | 3 | 0 | 0 | 0 | 1.50 | 8.10 | 0.00 | 5.40 | 8.10 | 2.70 | 1.50 | 1999- UDFA -HOU | premium | premium | premium | MLB | 2005-2015 | 2001-2015 | 2005 |
| - | Roberto Giron | 29 | R | 2 | 3 | 3.07 | 21 | 0 | 0 | 0 | 21 | 14 | 0 | 29.1 | 27 | 11 | 10 | 3 | 6 | 28 | 0 | 0 | 3 | 1.13 | 8.28 | 0.92 | 1.84 | 8.59 | 3.38 | 4.67 | premium | premium | premium | AAA | 1995-2013 | 2005 | ||
| - | Kevin Hodge | 28 | R | 1 | 4 | 5.48 | 14 | 0 | 0 | 0 | 14 | 7 | 2 | 23.0 | 23 | 15 | 14 | 3 | 8 | 25 | 2 | 0 | 1 | 1.35 | 9.00 | 1.17 | 3.13 | 9.78 | 5.87 | 3.13 | 1998- 19- 559-MIN | premium | premium | premium | AAA | 1998-2005 | 2005 | |
| 46 | Jason Hirsh | 23 | R | 13 | 8 | 2.87 | 29 | 29 | 1 | 1 | 0 | 0 | 0 | 172.1 | 137 | 63 | 55 | 12 | 42 | 165 | 7 | 1 | 12 | 1.04 | 7.15 | 0.63 | 2.19 | 8.62 | 3.29 | 3.93 | 2003- 2- 59-HOU | premium | premium | premium | MLB | 2006-2008 | 2003-2013 | 2005 |
| 22 | Tim McClaskey | 29 | R | 8 | 10 | 3.33 | 27 | 26 | 2 | 0 | 1 | 0 | 0 | 159.2 | 141 | 67 | 59 | 16 | 21 | 105 | 2 | 0 | 11 | 1.01 | 7.95 | 0.90 | 1.18 | 5.92 | 3.78 | 5.00 | 1995- 36- 989-MIA | premium | premium | premium | AAA | 1996-2008 | 2005 | |
| 32 | Chris Sampson | 27 | R | 4 | 12 | 3.12 | 32 | 19 | 2 | 1 | 13 | 9 | 4 | 150.0 | 147 | 67 | 52 | 11 | 19 | 92 | 2 | 0 | 4 | 1.11 | 8.82 | 0.66 | 1.14 | 5.52 | 4.02 | 4.84 | 1999- 8- 263-HOU | premium | premium | premium | MLB | 2006-2010 | 1999-2011 | 2005 |
| 14 | Philip Barzilla | 26 | L | 7 | 7 | 3.03 | 41 | 14 | 0 | 0 | 27 | 8 | 0 | 113.0 | 126 | 49 | 38 | 6 | 30 | 87 | 6 | 0 | 4 | 1.38 | 10.04 | 0.48 | 2.39 | 6.93 | 3.90 | 2.90 | 2001- 4- 116-HOU | premium | premium | premium | MLB | 2006-2006 | 2000-2010 | 2005 |
| 4 | Eric Riggs | 28 | R | 0 | 1 | 45.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 3 | 5 | 5 | 0 | 3 | 0 | 0 | 0 | 0 | 6.00 | 27.00 | 0.00 | 27.00 | 0.00 | 45.00 | 0.00 | 1998- 4- 126-LAN | premium | premium | premium | AAA | 1996-2007 | 2005 | |
| Totals: | 64 | 76 | 3.33 | 421 | 141 | 6 | 2 | 135 | 280 | 23 | 1257.0 | 1147 | 551 | 465 | 106 | 362 | 1036 | 51 | 4 | 59 | 1.20 | 8.21 | 0.76 | 2.59 | 7.42 | 3.95 | 2.86 | premium | premium | premium |