| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 10 | Max Alvis | 27 | 3B | R | 103 | 159 | 604 | 88 | 149 | 24 | 2 | 21 | 61 | 12 | 8 | 47 | 121 | 9 | 5 | 5 | 4 | 9 | 240 | 670 | 47 | 102 | .247 | .308 | .397 | .705 | .235 | .150 | .274 | 7.01 | 18.06 | 2.57 | 28.76 | 1958- UDFA -CLE | premium | premium | premium | MLB | 1962-1970 | 1962-1970 | 1965 |
| 21 | Rocky Colavito | 31 | OF | R | 123 | 162 | 592 | 92 | 170 | 25 | 2 | 26 | 108 | 1 | 1 | 93 | 63 | 3 | 0 | 7 | 11 | 14 | 277 | 695 | 53 | 117 | .287 | .383 | .468 | .851 | .338 | .181 | .282 | 13.38 | 9.06 | 0.68 | 22.77 | premium | premium | premium | MLB | 1955-1968 | 1955-1968 | 1965 | |
| 27 | Leon Wagner | 31 | OF | L | 125 | 144 | 517 | 91 | 152 | 18 | 1 | 28 | 79 | 12 | 2 | 60 | 52 | 3 | 0 | 3 | 8 | 6 | 256 | 583 | 47 | 105 | .294 | .369 | .495 | .864 | .337 | .201 | .282 | 10.29 | 8.92 | 0.87 | 18.46 | 1942- UDFA -NY1 | premium | premium | premium | MLB | 1958-1969 | 1958-1969 | 1965 |
| 25 | Vic Davalillo | 28 | OF | L | 106 | 142 | 505 | 67 | 152 | 19 | 1 | 5 | 40 | 26 | 7 | 35 | 50 | 0 | 6 | 4 | 9 | 4 | 188 | 550 | 25 | 127 | .301 | .344 | .372 | .716 | .178 | .071 | .324 | 6.36 | 9.09 | 1.43 | 101.00 | 1958- UDFA -CIN | premium | premium | premium | MLB | 1963-1980 | 1963-1980 | 1965 |
| 15 | Fred Whitfield | 27 | 1B | L | 117 | 132 | 468 | 49 | 137 | 23 | 1 | 26 | 90 | 2 | 2 | 16 | 42 | 2 | 2 | 4 | 7 | 12 | 240 | 492 | 50 | 87 | .293 | .316 | .513 | .829 | .254 | .220 | .275 | 3.25 | 8.54 | 2.63 | 18.00 | 1956- UDFA -PIT | premium | premium | premium | MLB | 1962-1970 | 1962-1970 | 1965 |
| 16 | Larry Brown | 25 | SS | R | 100 | 124 | 438 | 52 | 111 | 22 | 2 | 8 | 40 | 5 | 7 | 38 | 62 | 2 | 10 | 2 | 0 | 6 | 161 | 490 | 32 | 79 | .253 | .315 | .368 | .683 | .196 | .115 | .278 | 7.76 | 12.65 | 1.63 | 54.75 | 1958- UDFA -CLE | premium | premium | premium | MLB | 1963-1974 | 1963-1974 | 1965 |
| 23 | Chuck Hinton | 31 | OF-1B | R | 116 | 133 | 431 | 59 | 110 | 17 | 6 | 18 | 54 | 17 | 3 | 53 | 65 | 1 | 5 | 3 | 2 | 8 | 193 | 493 | 41 | 69 | .255 | .336 | .448 | .784 | .348 | .193 | .262 | 10.75 | 13.18 | 1.23 | 23.94 | 1956- UDFA -BAL | premium | premium | premium | MLB | 1961-1971 | 1961-1971 | 1965 |
| 24 | Pedro Gonzalez | 27 | 2B | R | 91 | 116 | 400 | 38 | 101 | 14 | 3 | 5 | 39 | 7 | 4 | 18 | 57 | 3 | 8 | 3 | 7 | 7 | 136 | 432 | 22 | 79 | .253 | .288 | .340 | .628 | .140 | .087 | .282 | 4.17 | 13.19 | 3.17 | 80.00 | 1958- UDFA -NYA | premium | premium | premium | MLB | 1963-1967 | 1963-1967 | 1965 |
| 6 | Joe Azcue | 25 | C | R | 82 | 111 | 335 | 16 | 77 | 7 | 0 | 2 | 35 | 2 | 1 | 27 | 54 | 3 | 2 | 4 | 8 | 15 | 90 | 371 | 9 | 68 | .230 | .290 | .269 | .559 | .122 | .039 | .265 | 7.28 | 14.56 | 2.00 | 167.50 | 1956- UDFA -CIN | premium | premium | premium | MLB | 1960-1972 | 1960-1972 | 1965 |
| 18 | Dick Howser | 29 | SS | R | 101 | 107 | 307 | 47 | 72 | 8 | 2 | 1 | 6 | 17 | 4 | 57 | 25 | 1 | 10 | 2 | 0 | 5 | 87 | 377 | 11 | 61 | .235 | .354 | .283 | .637 | .277 | .048 | .251 | 15.12 | 6.63 | 0.44 | 307.00 | 1958- UDFA -KC1 | premium | premium | premium | MLB | 1961-1968 | 1961-1968 | 1965 |
| 17 | Chico Salmon | 24 | 1B-OF | R | 97* | 79 | 120 | 20 | 29 | 8 | 0 | 3 | 12 | 7 | 4 | 5 | 19 | 2 | 5 | 1 | 0 | 2 | 46 | 133 | 11 | 18 | .242 | .281 | .383 | .664 | .208 | .141 | .263 | 3.76 | 14.29 | 3.80 | 40.00 | 1959- UDFA -WS1 | premium | premium | premium | MLB | 1964-1972 | 1964-1972 | 1965 |
| 9 | Duke Sims | 24 | C | L | 89* | 48 | 118 | 9 | 21 | 0 | 0 | 6 | 15 | 0 | 0 | 15 | 33 | 0 | 0 | 0 | 2 | 2 | 39 | 133 | 6 | 15 | .178 | .271 | .331 | .602 | .280 | .153 | .190 | 11.28 | 24.81 | 2.20 | 19.67 | 1959- UDFA -CLE | premium | premium | premium | MLB | 1964-1974 | 1964-1974 | 1965 |
| 48 | Sam McDowell | 22 | P | L | 43 | 95 | 5 | 12 | 1 | 0 | 0 | 4 | 0 | 0 | 1 | 35 | 0 | 5 | 0 | 0 | 0 | 13 | 101 | 1 | 11 | .126 | .135 | .137 | .272 | .021 | .011 | .200 | 0.99 | 34.65 | 35.00 | 0.00 | 1960- UDFA -CLE | premium | premium | premium | MLB | 1961-1975 | 1961-1975 | 1965 | |
| 33 | Luis Tiant | 24 | P | R | 41 | 68 | 2 | 6 | 0 | 0 | 1 | 3 | 0 | 0 | 3 | 30 | 0 | 4 | 0 | 0 | 1 | 9 | 75 | 1 | 5 | .088 | .127 | .132 | .259 | .088 | .044 | .135 | 4.00 | 40.00 | 10.00 | 68.00 | 1962- UDFA -CLE | premium | premium | premium | MLB | 1964-1982 | 1964-1982 | 1965 | |
| 42 | Sonny Siebert | 28 | P | R | 40 | 66 | 2 | 7 | 1 | 0 | 1 | 4 | 0 | 0 | 0 | 18 | 0 | 1 | 1 | 0 | 2 | 11 | 68 | 2 | 5 | .106 | .104 | .167 | .271 | .061 | .061 | .125 | 0.00 | 26.47 | 0.00 | 66.00 | 1958- UDFA -CLE | premium | premium | premium | MLB | 1964-1975 | 1964-1975 | 1965 | |
| 7 | Cam Carreon | 27 | C | R | 19 | 52 | 6 | 12 | 2 | 1 | 1 | 7 | 1 | 1 | 9 | 6 | 0 | 1 | 0 | 3 | 2 | 19 | 62 | 4 | 8 | .231 | .344 | .365 | .709 | .308 | .134 | .244 | 14.52 | 9.68 | 0.67 | 52.00 | 1956- UDFA -CHA | premium | premium | premium | MLB | 1959-1966 | 1959-1966 | 1965 | |
| 7 | Phil Roof | 24 | C | R | 43 | 52 | 3 | 9 | 1 | 0 | 0 | 3 | 0 | 0 | 5 | 13 | 1 | 3 | 0 | 1 | 1 | 10 | 61 | 1 | 8 | .173 | .259 | .192 | .451 | .115 | .019 | .231 | 8.20 | 21.31 | 2.60 | 0.00 | 1959- UDFA -MLN | premium | premium | premium | MLB | 1964-1977 | 1964-1977 | 1965 | |
| 32 | Ralph Terry | 29 | P | R | 30 | 49 | 2 | 7 | 2 | 0 | 1 | 4 | 0 | 0 | 4 | 21 | 1 | 10 | 0 | 0 | 0 | 12 | 64 | 3 | 4 | .143 | .222 | .245 | .467 | .184 | .102 | .222 | 6.25 | 32.81 | 5.25 | 49.00 | premium | premium | premium | MLB | 1956-1967 | 1956-1967 | 1965 | ||
| 22 | Al Luplow | 26 | OF | L | 53 | 45 | 3 | 6 | 2 | 0 | 1 | 4 | 0 | 1 | 3 | 14 | 0 | 0 | 0 | 0 | 1 | 11 | 48 | 3 | 3 | .133 | .188 | .244 | .432 | .156 | .111 | .167 | 6.25 | 29.17 | 4.67 | 45.00 | 1959- UDFA -CLE | premium | premium | premium | MLB | 1961-1967 | 1961-1967 | 1965 | |
| 20 | Lou Clinton | 27 | OF | R | 94 | 12 | 34 | 2 | 6 | 1 | 0 | 1 | 2 | 0 | 0 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 10 | 37 | 2 | 4 | .176 | .243 | .294 | .537 | .206 | .118 | .192 | 8.11 | 18.92 | 2.33 | 34.00 | 1955- UDFA -BOS | premium | premium | premium | MLB | 1960-1967 | 1960-1967 | 1965 |
| 43 | Lee Stange | 28 | P | R | 41 | 28 | 4 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 7 | 12 | 1 | 4 | 0 | 0 | 0 | 3 | 40 | 0 | 3 | .107 | .306 | .107 | .413 | .250 | .000 | .188 | 17.50 | 30.00 | 1.71 | 0.00 | 1957- UDFA -WS1 | premium | premium | premium | MLB | 1961-1970 | 1961-1970 | 1965 | |
| 11 | Billy Moran | 31 | 2B | R | 22 | 24 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5 | 1 | 0 | 0 | 0 | 0 | 3 | 27 | 0 | 3 | .125 | .222 | .125 | .347 | .083 | .000 | .158 | 7.41 | 18.52 | 2.50 | 0.00 | premium | premium | premium | MLB | 1958-1965 | 1958-1965 | 1965 | ||
| 31 | Jack Kralick | 30 | P | L | 30 | 21 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 8 | 0 | 3 | 1 | 0 | 0 | 3 | 25 | 0 | 3 | .143 | .136 | .143 | .279 | .000 | .000 | .214 | 0.00 | 32.00 | 0.00 | 0.00 | 1955- UDFA -CHA | premium | premium | premium | MLB | 1959-1967 | 1959-1967 | 1965 | |
| 34 | Steve Hargan | 22 | P | R | 17 | 19 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 2 | 0 | 0 | 0 | 1 | 21 | 0 | 1 | .053 | .053 | .053 | .106 | .000 | .000 | .077 | 0.00 | 28.57 | 0.00 | 0.00 | 1961- UDFA -CLE | premium | premium | premium | MLB | 1965-1977 | 1965-1978 | 1965 | |
| 39 | Gary Bell | 28 | P | R | 60 | 16 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 7 | 0 | 1 | 0 | 0 | 0 | 4 | 17 | 1 | 0 | .063 | .063 | .250 | .313 | .188 | .187 | .000 | 0.00 | 41.18 | 0.00 | 16.00 | premium | premium | premium | MLB | 1958-1969 | 1958-1969 | 1965 | ||
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 35 | Floyd Weaver | 24 | P | R | 32 | 11 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | 0 | 0 | 2 | 12 | 1 | 0 | .091 | .167 | .182 | .349 | .182 | .091 | .333 | 8.33 | 66.67 | 8.00 | 0.00 | 1961- UDFA -CLE | premium | premium | premium | MLB | 1962-1971 | 1962-1971 | 1965 | |
| 12 | Bill Davis | 23 | 1B | L | 10 | 10 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4 | 10 | 1 | 2 | .300 | .300 | .400 | .700 | .100 | .100 | .333 | 0.00 | 10.00 | 0.00 | 0.00 | 1964- UDFA -CLE | premium | premium | premium | MLB | 1965-1969 | 1965-1969 | 1965 | |
| 44 | Don McMahon | 35 | P | R | 58 | 9 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 1 | 0 | 0 | 0 | 2 | 10 | 0 | 2 | .222 | .222 | .222 | .444 | .000 | .000 | .500 | 0.00 | 50.00 | 0.00 | 0.00 | 1950- UDFA -BSN | premium | premium | premium | MLB | 1957-1974 | 1957-1974 | 1965 | |
| 45 | Tom Kelley | 21 | P | R | 4 | 9 | 1 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 6 | 0 | 1 | 0 | 0 | 0 | 2 | 11 | 0 | 2 | .222 | .300 | .222 | .522 | .111 | .000 | .667 | 9.09 | 54.55 | 6.00 | 0.00 | 1963- UDFA -CLE | premium | premium | premium | MLB | 1964-1973 | 1964-1976 | 1965 | |
| 30 | Dick Donovan | 37 | P | L | 12 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 66.67 | 0.00 | 0.00 | premium | premium | premium | MLB | 1950-1965 | 1950-1965 | 1965 | ||
| 50 | Ray Barker | 29 | 1B | L | 104 | 11 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 8 | 0 | 0 | .000 | .250 | .000 | .250 | .333 | .000 | .000 | 25.00 | 25.00 | 1.00 | 0.00 | 1955- UDFA -BAL | premium | premium | premium | MLB | 1960-1967 | 1960-1967 | 1965 |
| 6 | George Banks | 26 | 3B | R | 4 | 5 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 2 | 6 | 1 | 0 | .200 | .333 | .400 | .733 | .200 | .200 | .500 | 16.67 | 50.00 | 3.00 | 0.00 | 1957- UDFA -NYA | premium | premium | premium | MLB | 1962-1966 | 1962-1966 | 1965 | |
| 49 | Jack Spring | 32 | P | R | 14 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .333 | .333 | .333 | .666 | .000 | .000 | .500 | 0.00 | 25.00 | 0.00 | 0.00 | premium | premium | premium | MLB | 1955-1965 | 1955-1965 | 1965 | ||
| 14 | Tony Martinez | 25 | SS | R | 4 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1960- UDFA -CLE | premium | premium | premium | MLB | 1963-1966 | 1963-1966 | 1965 | |
| 36 | Bobby Tiefenauer | 35 | P | R | 15 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | premium | premium | premium | MLB | 1952-1968 | 1952-1968 | 1965 | ||
| 41 | Mike Hedlund | 18 | P | R | 6 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 1964- UDFA -CLE | premium | premium | premium | MLB | 1965-1972 | 1965-1972 | 1965 | |
| 25,28 | Richie Scheinblum | 22 | OF | B | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1964- UDFA -CLE | premium | premium | premium | MLB | 1965-1974 | 1965-1974 | 1965 | |
| Totals: | 2082 | 5469 | 663 | 1367 | 198 | 21 | 156 | 615 | 109 | 46 | 506 | 857 | 33 | 90 | 40 | 63 | 97 | 2075 | 6138 | 375 | 992 | .250 | .315 | .379 | .695 | .233 | .129 | .269 | 8.24 | 13.96 | 1.69 | 35.06 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 31 | Jack Kralick | 30 | L | 5 | 11 | 4.92 | 30 | 16 | 1 | 0 | 14 | 2 | 0 | 86.0 | 106 | 58 | 47 | 9 | 21 | 34 | 2 | 0 | 2 | 1.48 | 11.09 | 0.94 | 2.20 | 3.56 | 6.07 | 1.62 | 1955- UDFA -CHA | premium | premium | premium | MLB | 1959-1967 | 1959-1967 | 1965 |
| 44 | Don McMahon | 35 | R | 3 | 3 | 3.28 | 58 | 0 | 0 | 0 | 58 | 31 | 11 | 85.0 | 79 | 36 | 31 | 8 | 37 | 60 | 8 | 0 | 1 | 1.36 | 8.36 | 0.85 | 3.92 | 6.35 | 3.81 | 1.62 | 1950- UDFA -BSN | premium | premium | premium | MLB | 1957-1974 | 1957-1974 | 1965 |
| 35 | Floyd Weaver | 24 | R | 2 | 2 | 5.43 | 32 | 1 | 0 | 0 | 31 | 10 | 1 | 61.1 | 61 | 40 | 37 | 10 | 24 | 37 | 2 | 0 | 5 | 1.39 | 8.95 | 1.47 | 3.52 | 5.43 | 5.87 | 1.54 | 1961- UDFA -CLE | premium | premium | premium | MLB | 1962-1971 | 1962-1971 | 1965 |
| 34 | Steve Hargan | 22 | R | 4 | 3 | 3.43 | 17 | 8 | 1 | 0 | 9 | 4 | 2 | 60.1 | 55 | 26 | 23 | 2 | 28 | 37 | 7 | 0 | 1 | 1.38 | 8.20 | 0.30 | 4.18 | 5.52 | 3.88 | 1.32 | 1961- UDFA -CLE | premium | premium | premium | MLB | 1965-1977 | 1965-1978 | 1965 |
| 41 | Mike Hedlund | 18 | R | 0 | 0 | 5.06 | 6 | 0 | 0 | 0 | 6 | 1 | 0 | 5.1 | 6 | 4 | 3 | 0 | 5 | 4 | 1 | 0 | 0 | 2.06 | 10.13 | 0.00 | 8.44 | 6.75 | 6.75 | 0.80 | 1964- UDFA -CLE | premium | premium | premium | MLB | 1965-1972 | 1965-1972 | 1965 |
| 40 | Stan Williams | 28 | R | 0 | 0 | 6.23 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 4.1 | 6 | 4 | 3 | 1 | 3 | 1 | 0 | 0 | 0 | 2.08 | 12.46 | 2.08 | 6.23 | 2.08 | 8.31 | 0.33 | premium | premium | premium | MLB | 1958-1972 | 1958-1972 | 1965 | |
| 45 | Tom Kelley | 21 | R | 2 | 1 | 2.40 | 4 | 4 | 1 | 0 | 0 | 0 | 0 | 30.0 | 19 | 8 | 8 | 3 | 13 | 31 | 2 | 0 | 0 | 1.07 | 5.70 | 0.90 | 3.90 | 9.30 | 2.40 | 2.38 | 1963- UDFA -CLE | premium | premium | premium | MLB | 1964-1973 | 1964-1976 | 1965 |
| 48 | Sam McDowell | 22 | L | 17 | 11 | 2.18 | 42 | 35 | 14 | 3 | 7 | 5 | 4 | 273.0 | 178 | 80 | 66 | 9 | 132 | 325 | 17 | 0 | 6 | 1.14 | 5.87 | 0.30 | 4.35 | 10.71 | 2.64 | 2.46 | 1960- UDFA -CLE | premium | premium | premium | MLB | 1961-1975 | 1961-1975 | 1965 |
| 30 | Dick Donovan | 37 | R | 1 | 3 | 5.96 | 12 | 3 | 0 | 0 | 9 | 2 | 0 | 22.2 | 32 | 15 | 15 | 6 | 6 | 12 | 2 | 0 | 0 | 1.68 | 12.71 | 2.38 | 2.38 | 4.76 | 5.96 | 2.00 | premium | premium | premium | MLB | 1950-1965 | 1950-1965 | 1965 | |
| 36 | Bobby Tiefenauer | 35 | R | 0 | 5 | 4.84 | 15 | 0 | 0 | 0 | 15 | 10 | 4 | 22.1 | 24 | 17 | 12 | 3 | 10 | 13 | 1 | 0 | 1 | 1.52 | 9.67 | 1.21 | 4.03 | 5.24 | 6.85 | 1.30 | premium | premium | premium | MLB | 1952-1968 | 1952-1968 | 1965 | |
| 49 | Jack Spring | 32 | L | 1 | 2 | 3.74 | 14 | 0 | 0 | 0 | 14 | 7 | 0 | 21.2 | 21 | 9 | 9 | 2 | 10 | 9 | 0 | 0 | 0 | 1.43 | 8.72 | 0.83 | 4.15 | 3.74 | 3.74 | 0.90 | premium | premium | premium | MLB | 1955-1965 | 1955-1965 | 1965 | |
| 33 | Luis Tiant | 24 | R | 11 | 11 | 3.53 | 41 | 30 | 10 | 2 | 11 | 4 | 1 | 196.1 | 166 | 88 | 77 | 20 | 66 | 152 | 2 | 0 | 3 | 1.18 | 7.61 | 0.92 | 3.03 | 6.97 | 4.03 | 2.30 | 1962- UDFA -CLE | premium | premium | premium | MLB | 1964-1982 | 1964-1982 | 1965 |
| 42 | Sonny Siebert | 28 | R | 16 | 8 | 2.43 | 39 | 27 | 4 | 1 | 12 | 5 | 1 | 188.2 | 139 | 58 | 51 | 14 | 46 | 191 | 3 | 1 | 5 | 0.98 | 6.63 | 0.67 | 2.19 | 9.11 | 2.77 | 4.15 | 1958- UDFA -CLE | premium | premium | premium | MLB | 1964-1975 | 1964-1975 | 1965 |
| 32 | Ralph Terry | 29 | R | 11 | 6 | 3.69 | 30 | 26 | 6 | 2 | 4 | 1 | 0 | 165.2 | 154 | 77 | 68 | 22 | 23 | 84 | 0 | 0 | 1 | 1.07 | 8.37 | 1.20 | 1.25 | 4.56 | 4.18 | 3.65 | premium | premium | premium | MLB | 1956-1967 | 1956-1967 | 1965 | |
| 43 | Lee Stange | 28 | R | 8 | 4 | 3.34 | 41 | 12 | 4 | 2 | 29 | 6 | 0 | 132.0 | 122 | 50 | 49 | 13 | 26 | 80 | 1 | 0 | 1 | 1.12 | 8.32 | 0.89 | 1.77 | 5.45 | 3.41 | 3.08 | 1957- UDFA -WS1 | premium | premium | premium | MLB | 1961-1970 | 1961-1970 | 1965 |
| 39 | Gary Bell | 28 | R | 6 | 5 | 3.04 | 60 | 0 | 0 | 0 | 60 | 33 | 17 | 103.2 | 86 | 43 | 35 | 7 | 50 | 86 | 2 | 0 | 2 | 1.31 | 7.47 | 0.61 | 4.34 | 7.47 | 3.73 | 1.72 | premium | premium | premium | MLB | 1958-1969 | 1958-1969 | 1965 | |
| Totals: | 87 | 75 | 3.30 | 444 | 162 | 41 | 10 | 121 | 282 | 41 | 1458.1 | 1254 | 613 | 534 | 129 | 500 | 1156 | 50 | 1 | 28 | 1.20 | 7.74 | 0.80 | 3.09 | 7.13 | 3.78 | 2.31 | premium | premium | premium |