| year | team | league | level | age | pos | g | gs | inn | po | a | e | dp | tc | tsc | sb | cs | sb% | fpct | rfg | rfi | rf9i | tm share | pl share | tm rank |
| 1999 | Burlington Bees | Midw | A | 20 | P | 20 | 0 | 0.0 | 9 | 23 | 4 | 0 | 36 | 32 | 0 | 0 | .889 | 1.6 | 0.00 | 0.00 | 14.4 | 100.0 | 9 | |
| 2000 | Chicago White Sox | AL | MLB | 21 | P | 28 | 3 | 51.1 | 1 | 9 | 1 | 2 | 11 | 10 | 1 | 3 | 0.25 | .909 | 0.4 | 0.20 | 1.80 | 17.3 | 100.0 | 10 |
| 2000 | Birmingham Barons | Sou | AA | 21 | P | 16 | 0 | 0.0 | 5 | 38 | 2 | 3 | 45 | 43 | 0 | 0 | .956 | 2.7 | 0.00 | 0.00 | 11.4 | 100.0 | 13 | |
| 2001 | Chicago White Sox | AL | MLB | 22 | P | 32 | 32 | 221.1 | 11 | 49 | 3 | 5 | 63 | 60 | 6 | 6 | 0.5 | .952 | 1.9 | 0.27 | 2.43 | 19.8 | 100.0 | 9 |
| 2002 | Chicago White Sox | AL | MLB | 23 | P | 34 | 34 | 239.0 | 6 | 46 | 2 | 2 | 54 | 52 | 4 | 10 | 0.2857 | .963 | 1.5 | 0.22 | 1.98 | 21.0 | 100.0 | 8 |
| 2003 | Chicago White Sox | AL | MLB | 24 | P | 35 | 35 | 230.1 | 15 | 38 | 0 | 3 | 53 | 53 | 0 | 0 | 1.000 | 1.5 | 0.23 | 2.07 | 21.6 | 100.0 | 5 | |
| 2004 | Chicago White Sox | AL | MLB | 25 | P | 35 | 35 | 245.1 | 16 | 51 | 4 | 3 | 71 | 67 | 0 | 0 | .944 | 1.9 | 0.27 | 2.43 | 21.6 | 100.0 | 7 | |
| 2005 | Chicago White Sox | AL | MLB | 26 | P | 33 | 33 | 236.2 | 13 | 45 | 2 | 2 | 60 | 58 | 0 | 0 | .967 | 1.8 | 0.25 | 2.25 | 20.4 | 100.0 | 6 | |
| 2006 | Chicago White Sox | AL | MLB | 27 | P | 32 | 32 | 204.0 | 9 | 35 | 1 | 3 | 45 | 44 | 0 | 0 | .978 | 1.4 | 0.22 | 1.98 | 19.8 | 100.0 | 9 | |
| 2007 | Chicago White Sox | AL | MLB | 28 | P | 30 | 30 | 201.0 | 13 | 34 | 1 | 3 | 48 | 47 | 0 | 0 | .979 | 1.6 | 0.23 | 2.07 | 18.5 | 100.0 | 10 | |
| 2008 | Chicago White Sox | AL | MLB | 29 | P | 34 | 34 | 218.0 | 18 | 34 | 0 | 5 | 52 | 52 | 0 | 0 | 1.000 | 1.5 | 0.24 | 2.16 | 20.9 | 100.0 | 6 | |
| 2009 | Chicago White Sox | AL | MLB | 30 | P | 33 | 33 | 213.1 | 13 | 41 | 1 | 5 | 55 | 54 | 0 | 0 | .982 | 1.6 | 0.25 | 2.25 | 20.4 | 100.0 | 7 | |
| 2010 | Chicago White Sox | AL | MLB | 31 | P | 33 | 33 | 210.1 | 4 | 46 | 0 | 4 | 50 | 50 | 0 | 0 | 1.000 | 1.5 | 0.24 | 2.16 | 20.4 | 100.0 | 7 | |
| 2011 | Chicago White Sox | AL | MLB | 32 | P | 31 | 31 | 205.1 | 15 | 40 | 1 | 4 | 56 | 55 | 0 | 0 | .982 | 1.8 | 0.27 | 2.43 | 19.1 | 100.0 | 6 | |
| 2012 | Miami Marlins | NL | MLB | 33 | P | 31 | 31 | 202.1 | 13 | 47 | 0 | 5 | 60 | 60 | 5 | 3 | 0.625 | 1.000 | 1.9 | 0.30 | 2.70 | 19.1 | 100.0 | 9 |
| 2013 | Toronto Blue Jays | AL | MLB | 34 | P | 33 | 33 | 203.2 | 12 | 35 | 2 | 1 | 49 | 47 | 4 | 5 | 0.4444 | .959 | 1.4 | 0.23 | 2.07 | 20.4 | 100.0 | 9 |
| 2014 | Toronto Blue Jays | AL | MLB | 35 | P | 32 | 32 | 202.0 | 12 | 29 | 1 | 2 | 42 | 41 | 1 | 3 | 0.25 | .976 | 1.3 | 0.20 | 1.80 | 19.8 | 100.0 | 7 |
| 2015 | Toronto Blue Jays | AL | MLB | 36 | P | 32 | 32 | 198.2 | 11 | 29 | 3 | 4 | 43 | 40 | 0 | 2 | 0 | .930 | 1.3 | 0.20 | 1.80 | 19.8 | 100.0 | 8 |
| Tot: | MLB (16 yrs) | MLB | P | 518 | 493 | 3,279.4 | 182 | 608 | 22 | 53 | 812 | 790 | 21 | 32 | 0.3962 | .973 | 1.5 | 0.24 | 2.17 | |||||
| Tot: | AA (1 yrs) | AA | P | 16 | 0 | 0.0 | 5 | 38 | 2 | 3 | 45 | 43 | 0 | 0 | .956 | 2.7 | ||||||||
| Tot: | A (1 yrs) | A | P | 20 | 0 | 0.0 | 9 | 23 | 4 | 0 | 36 | 32 | 0 | 0 | .889 | 1.6 |
| year | category | pos P | pos C | pos 1B | pos 2B | pos 3B | pos SS | pos LF | pos CF | pos RF | pos OF | pos DH |
| 1999 | Minor | 20 | - | - | - | - | - | - | - | - | - | - |
| 2000 | Minor | 16 | - | - | - | - | - | - | - | - | - | - |
| 2000 | MLB | 28 | - | - | - | - | - | - | - | - | - | - |
| 2001 | MLB | 32 | - | - | - | - | - | - | - | - | - | - |
| 2002 | MLB | 34 | - | - | - | - | - | - | - | - | - | - |
| 2003 | MLB | 35 | - | - | - | - | - | - | - | - | - | - |
| 2004 | MLB | 35 | - | - | - | - | - | - | - | - | - | - |
| 2005 | MLB | 33 | - | - | - | - | - | - | - | - | - | - |
| 2006 | MLB | 32 | - | - | - | - | - | - | - | - | - | - |
| 2007 | MLB | 30 | - | - | - | - | - | - | - | - | - | - |
| 2008 | MLB | 34 | - | - | - | - | - | - | - | - | - | - |
| 2009 | MLB | 33 | - | - | - | - | - | - | - | - | - | - |
| 2010 | MLB | 33 | - | - | - | - | - | - | - | - | - | - |
| 2011 | MLB | 31 | - | - | - | - | - | - | - | - | - | - |
| 2012 | MLB | 31 | - | - | - | - | - | - | - | - | - | - |
| 2013 | MLB | 33 | - | - | - | - | - | - | - | - | - | - |
| 2014 | MLB | 32 | - | - | - | - | - | - | - | - | - | - |
| 2015 | MLB | 32 | - | - | - | - | - | - | - | - | - | - |