| year | team | league | level | age | pos | g | gs | inn | po | a | e | dp | tc | tsc | sb | cs | sb% | fpct | rfg | rfi | rf9i | tm share | pl share | tm rank |
| 2005 | Detroit Tigers | AL | MLB | 22 | P | 2 | 2 | 11.1 | 2 | 2 | 1 | 0 | 5 | 4 | 0 | 0 | .800 | 2.0 | 0.36 | 3.24 | 1.2 | 100.0 | 22 | |
| 2005 | Erie SeaWolves | East | AA | 22 | P | 7 | 0 | 0.0 | 2 | 6 | 1 | 0 | 9 | 8 | 0 | 0 | .889 | 1.1 | 0.00 | 0.00 | 4.9 | 100.0 | 16 | |
| 2005 | Lakeland Tigers | FSL | A+ | 22 | P | 13 | 0 | 0.0 | 11 | 12 | 2 | 0 | 25 | 23 | 0 | 0 | .920 | 1.8 | 0.00 | 0.00 | 9.8 | 100.0 | 13 | |
| 2006 | Detroit Tigers | AL | MLB | 23 | P | 30 | 30 | 186.0 | 11 | 24 | 3 | 4 | 38 | 35 | 0 | 0 | .921 | 1.2 | 0.19 | 1.71 | 18.5 | 100.0 | 9 | |
| 2007 | Detroit Tigers | AL | MLB | 24 | P | 32 | 32 | 202.2 | 7 | 17 | 0 | 0 | 24 | 24 | 0 | 0 | 1.000 | 0.8 | 0.12 | 1.08 | 19.8 | 100.0 | 8 | |
| 2008 | Detroit Tigers | AL | MLB | 25 | P | 33 | 33 | 201.0 | 7 | 24 | 2 | 1 | 33 | 31 | 0 | 0 | .939 | 0.9 | 0.15 | 1.35 | 20.4 | 100.0 | 7 | |
| 2009 | Detroit Tigers | AL | MLB | 26 | P | 35 | 35 | 240.0 | 14 | 20 | 2 | 4 | 36 | 34 | 0 | 0 | .944 | 1.0 | 0.14 | 1.26 | 21.5 | 100.0 | 7 | |
| 2010 | Detroit Tigers | AL | MLB | 27 | P | 33 | 33 | 224.1 | 15 | 34 | 2 | 3 | 51 | 49 | 0 | 0 | .961 | 1.5 | 0.22 | 1.98 | 20.4 | 100.0 | 6 | |
| 2011 | Detroit Tigers | AL | MLB | 28 | P | 34 | 34 | 251.0 | 12 | 33 | 5 | 2 | 50 | 45 | 0 | 0 | .900 | 1.3 | 0.18 | 1.62 | 21.0 | 100.0 | 7 | |
| 2012 | Detroit Tigers | AL | MLB | 29 | P | 33 | 33 | 238.1 | 25 | 24 | 4 | 3 | 53 | 49 | 16 | 4 | 0.8 | .925 | 1.5 | 0.21 | 1.89 | 20.4 | 100.0 | 6 |
| 2013 | Detroit Tigers | AL | MLB | 30 | P | 34 | 34 | 218.1 | 19 | 17 | 2 | 5 | 38 | 36 | 21 | 4 | 0.84 | .947 | 1.1 | 0.17 | 1.53 | 21.0 | 100.0 | 5 |
| 2014 | Detroit Tigers | AL | MLB | 31 | P | 32 | 32 | 206.0 | 10 | 23 | 6 | 2 | 39 | 33 | 13 | 4 | 0.7647 | .846 | 1.0 | 0.16 | 1.44 | 19.8 | 100.0 | 8 |
| 2015 | Detroit Tigers | AL | MLB | 32 | P | 20 | 20 | 133.1 | 8 | 6 | 3 | 1 | 17 | 14 | 3 | 4 | 0.4286 | .824 | 0.7 | 0.11 | 0.99 | 12.4 | 100.0 | 14 |
| 2015 | Toledo Mud Hens | IL | AAA | 32 | P | 2 | 0 | 0.0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1.000 | 0.5 | 0.00 | 0.00 | 1.4 | 100.0 | 27 | |
| 2016 | Detroit Tigers | AL | MLB | 33 | P | 34 | 34 | 227.2 | 7 | 29 | 1 | 2 | 37 | 36 | 5 | 6 | 0.4545 | .973 | 1.1 | 0.16 | 1.44 | 21.1 | 100.0 | 9 |
| 2017 | Detroit Tigers | AL | MLB | 34 | P | 28 | 28 | 172.0 | 8 | 13 | 1 | 0 | 22 | 21 | 9 | 1 | 0.9 | .955 | 0.8 | 0.12 | 1.08 | 17.3 | 100.0 | 8 |
| 2017 | Houston Astros | AL | MLB | 34 | P | 5 | 5 | 34.0 | 2 | 0 | 0 | 1 | 2 | 2 | 0 | 0 | 1.000 | 0.4 | 0.06 | 0.54 | 3.1 | 100.0 | 22 | |
| 2018 | Houston Astros | AL | MLB | 35 | P | 34 | 34 | 214.0 | 7 | 12 | 1 | 0 | 20 | 19 | 3 | 4 | 0.4286 | .950 | 0.6 | 0.09 | 0.81 | 21.0 | 100.0 | 8 |
| 2019 | Houston Astros | AL | MLB | 36 | P | 34 | 34 | 223.0 | 17 | 10 | 0 | 0 | 27 | 27 | 9 | 3 | 0.75 | 1.000 | 0.8 | 0.12 | 1.08 | 21.0 | 100.0 | 8 |
| 2020 | Houston Astros | AL | MLB | 37 | P | 1 | 1 | 6.0 | 2 | 1 | 0 | 0 | 3 | 3 | 0 | 0 | 1.000 | 3.0 | 0.50 | 4.50 | 1.7 | 100.0 | 26 | |
| 2022 | Houston Astros | AL | MLB | 39 | P | 28 | 28 | 175.0 | 4 | 15 | 1 | 2 | 20 | 19 | 10 | 3 | 0.7692 | .950 | 0.7 | 0.11 | 0.99 | 17.3 | 100.0 | 11 |
| 2023 | New York Mets | NL | MLB | 40 | P | 16 | 16 | 94.1 | 13 | 5 | 0 | 1 | 18 | 18 | 8 | 2 | 0.8 | 1.000 | 1.1 | 0.19 | 1.71 | 9.9 | 100.0 | 15 |
| 2023 | Houston Astros | AL | MLB | 40 | P | 11 | 11 | 68.0 | 11 | 1 | 0 | 0 | 12 | 12 | 3 | 0 | 1 | 1.000 | 1.1 | 0.18 | 1.62 | 6.8 | 100.0 | 17 |
| 2023 | Binghamton Rumble Ponies | East2 | AA | 40 | P | 1 | 0 | 4.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | 0.0 | 0.00 | 0.00 | 0.7 | 100.0 | 39 | |
| 2024 | Houston Astros | AL | MLB | 41 | P | 17 | 17 | 90.1 | 4 | 5 | 0 | 0 | 9 | 9 | 8 | 3 | 0.7273 | 1.000 | 0.5 | 0.10 | 0.90 | 10.6 | 100.0 | 15 |
| 2024 | Sugar Land Space Cowboys | PCL2 | AAA | 41 | P | 2 | 0 | 6.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | 0.0 | 0.00 | 0.00 | 1.3 | 100.0 | 31 | |
| 2024 | Corpus Christi Hooks | Tex2 | AA | 41 | P | 2 | 0 | 8.0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1.000 | 0.5 | 0.13 | 1.17 | 1.5 | 100.0 | 29 | |
| 2025 | San Francisco Giants | NL | MLB | 42 | P | 29 | 29 | 152.0 | 9 | 10 | 1 | 0 | 20 | 19 | 13 | 7 | 0.65 | .950 | 0.7 | 0.13 | 1.17 | 17.9 | 100.0 | 11 |
| Tot: | MLB (20 yrs) | MLB | P | 555 | 555 | 3,566.1 | 214 | 325 | 35 | 31 | 574 | 539 | 121 | 45 | 0.7289 | .939 | 1.0 | 0.15 | 1.36 | |||||
| Tot: | AAA (2 yrs) | AAA | P | 4 | 0 | 6.0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1.000 | 0.3 | 0.17 | 1.50 | ||||||
| Tot: | AA (3 yrs) | AA | P | 10 | 0 | 12.2 | 2 | 7 | 1 | 0 | 10 | 9 | 0 | 0 | .900 | 0.9 | 0.74 | 6.64 | ||||||
| Tot: | A+ (1 yrs) | A+ | P | 13 | 0 | 0.0 | 11 | 12 | 2 | 0 | 25 | 23 | 0 | 0 | .920 | 1.8 |
| year | category | pos P | pos C | pos 1B | pos 2B | pos 3B | pos SS | pos LF | pos CF | pos RF | pos OF | pos DH |
| 2005 | Minor | 20 | - | - | - | - | - | - | - | - | - | - |
| 2005 | MLB | 2 | - | - | - | - | - | - | - | - | - | - |
| 2006 | MLB | 30 | - | - | - | - | - | - | - | - | - | - |
| 2007 | MLB | 32 | - | - | - | - | - | - | - | - | - | - |
| 2008 | MLB | 33 | - | - | - | - | - | - | - | - | - | - |
| 2009 | MLB | 35 | - | - | - | - | - | - | - | - | - | - |
| 2010 | MLB | 33 | - | - | - | - | - | - | - | - | - | - |
| 2011 | MLB | 34 | - | - | - | - | - | - | - | - | - | - |
| 2012 | MLB | 33 | - | - | - | - | - | - | - | - | - | - |
| 2013 | MLB | 34 | - | - | - | - | - | - | - | - | - | - |
| 2014 | MLB | 32 | - | - | - | - | - | - | - | - | - | - |
| 2015 | Minor | 2 | - | - | - | - | - | - | - | - | - | - |
| 2015 | MLB | 20 | - | - | - | - | - | - | - | - | - | - |
| 2016 | MLB | 34 | - | - | - | - | - | - | - | - | - | - |
| 2017 | MLB | 33 | - | - | - | - | - | - | - | - | - | - |
| 2018 | MLB | 34 | - | - | - | - | - | - | - | - | - | - |
| 2019 | MLB | 34 | - | - | - | - | - | - | - | - | - | - |
| 2020 | MLB | 1 | - | - | - | - | - | - | - | - | - | - |
| 2022 | MLB | 28 | - | - | - | - | - | - | - | - | - | - |
| 2023 | Minor | 1 | - | - | - | - | - | - | - | - | - | - |
| 2023 | MLB | 27 | - | - | - | - | - | - | - | - | - | - |
| 2024 | Minor | 4 | - | - | - | - | - | - | - | - | - | - |
| 2024 | MLB | 17 | - | - | - | - | - | - | - | - | - | - |
| 2025 | MLB | 29 | - | - | - | - | - | - | - | - | - | - |