| 2010 | Topps | | 2 | Buster Posey | RC | player cards | San Francisco Giants | c | Candid - In Dugout | Holding mask,RC |
| 2010 | Topps | | 6 | | Team Card | player cards | Chicago White Sox | | Celebration | Team Card,Hugging |
| 2010 | Topps | | 11 | Orlando Cabrera | | player cards | Minnesota Twins | ss | Action - Throwing | Sunglasses |
| 2010 | Topps | | 13 | Melvin Mora | | player cards | Baltimore Orioles | third base | Action - Throwing | |
| 2010 | Topps | | 18 | Tim Stauffer | | player cards | San Diego Padres | pitcher | Action - Pitching | Scoreboard |
| 2010 | Topps | | 32 |
| Team Card | player cards | Cincinnati Reds | | Celebration | Team Card,Mobbed by teammates |
| 2010 | Topps | | 33 | Adam Moore | RC | player cards | Seattle Mariners | c | Action - Baserunning | RC |
| 2010 | Topps | | 39 | Jeff Baker | | player cards | Chicago Cubs | 2b | Action - Baserunning | |
| 2010 | Topps | | 42 | Prince Fielder Ryan Howard Albert Pujols | NL RBI Leaders | player cards | Milwaukee Brewers Philadelphia Phillies St. Louis Cardinals | | Multiple | RBI Leaders,Leaders |
| 2010 | Topps | | 44 | Howie Kendrick | | player cards | Los Angeles Angels | 2b | Action - Throwing | Off-balance,Sunglasses |
| 2010 | Topps | | 51 | Eric Young Jr. | RC | player cards | Colorado Rockies | of | Action - Sliding | RC,Sliding,Play at the plate |
| 2010 | Topps | | 52 | Billy Butler | | player cards | Kansas City Royals | 1b | Action - Fielding | First base stretch |
| 2010 | Topps | | 56 | Andy Pettitte | | player cards | New York Yankees | p | Action - Pitching | Batter view |
| 2010 | Topps | | 57 | CC Sabathia | | player cards | New York Yankees | p | Action - Pitching | |
| 2010 | Topps | | 58 | Kyle Blanks | | player cards | San Diego Padres | of | Action - Batting | Alternate Uniform,Name visible on back,Swing extension |
| 2010 | Topps | | 64 | Drew Stubbs | RC | player cards | Cincinnati Reds | of | Action - Home Run Trot | Pumping fist,Dropping bat,RC |
| 2010 | Topps | | 67 | Matt LaPorta | | player cards | Cleveland Indians | of | Action - Fielding | Tracking flyball,Outfield fence,Sunglasses |
| 2010 | Topps | | 70 | Cole Hamels | | player cards | Philadelphia Phillies | p | Action - Pitching | Name visible on back |
| 2010 | Topps | | 71 | Mike Hampton | | player cards | Houston Astros | pitcher | Candid - Bullpen | |
| 2010 | Topps | | 72 | | Team card | player cards | Milwaukee Brewers | | Stadium | Team Card,Stadium |
| 2010 | Topps | | 75 | Adrian Gonzalez | | player cards | San Diego Padres | 1b | Action - Sliding | Head-first Slide |
| 2010 | Topps | | 78 | Cesar Izturis | | player cards | Baltimore Orioles | ss | Action - Batting | |
| 2010 | Topps | | 80 | Tim Lincecum | | player cards | San Francisco Giants | p | Action - Pitching | |
| 2010 | Topps | | 85 | Ken Griffey Jr. | | player cards | Seattle Mariners | dh | Action - Batting | |
| 2010 | Topps | | 87 | Darin Erstad | | player cards | Houston Astros | of | Action - Fielding | Scoreboard,Fielding ball in OF,Sunglasses |
| 2010 | Topps | | 112 | Kevin Correia | | player cards | San Diego Padres | p | Action - Pitching | Scoreboard,Alternate Uniform |
| 2010 | Topps | | 128 | Garrett Mock | | player cards | Washington Nationals | p | Action - Pitching | |
| 2010 | Topps | | 133 | Freddy Sanchez | | player cards | San Francisco Giants | 2b | Action - Batting | |
| 2010 | Topps | | 140 | Matt Holliday | | player cards | St. Louis Cardinals | of | Action - Batting | |
| 2010 | Topps | | 146 | Yunel Escobar | | player cards | Atlanta Braves | ss | Action - Fielding | Leaping,Double play |
| 2010 | Topps | | 148 | Cody Ross | | player cards | Florida Marlins | of | Action - Fielding | Diving |
| 2010 | Topps | | 159 | Vernon Wells | | player cards | Toronto Blue Jays | of | Action - Fielding | Catching ball,Sunglasses |
| 2010 | Topps | | 171 | Felix Hernandez CC Sabathia Justin Verlander | Wins Leaders | player cards | Seattle Mariners New York Yankees Detroit Tigers | | Multiple | Wins Leaders,Leaders |
| 2010 | Topps | | 177 | Adam Lind | | player cards | Toronto Blue Jays | of | Action - Batting | |
| 2010 | Topps | | 195 | James Shields | | player cards | Tampa Bay Rays | p | Action - Pitching | |
| 2010 | Topps | | 199 | | Team Card | player cards | Seattle Mariners | | Celebration | Team Card,Mobbed by teammates |
| 2010 | Topps | | 201 |
| Team Card | player cards | Detroit Tigers | | Celebration | Team Card,Slapping hands |
| 2010 | Topps | | 212 | Magglio Ordonez | | player cards | Detroit Tigers | of | Candid - On base | Throwing helmet,Ad-Verizon |
| 2010 | Topps | | 215 | Max Scherzer | | player cards | Arizona Diamondbacks | pitcher | Action - Pitching | Leg kick |
| 2010 | Topps | | 217 | Gio Gonzalez | | player cards | Oakland Athletics | p | Action - Pitching | Scoreboard,Name visible on back |
| 2010 | Topps | | 223 | Ryan Church | | player cards | Atlanta Braves | of | Action - Batting | Swing Follow-Through,Ad-CreditReport.Com |
| 2010 | Topps | | 236 | Andrew Bailey | AL Rookie of the Year | player cards | Oakland Athletics | p | Action - Pitching | Rookie of the Year,Award Winner |
| 2010 | Topps | | 242 | Bobby Jenks | | player cards | Chicago White Sox | p | Action - Pitching | |
| 2010 | Topps | | 250 | Mark Teixeira | | player cards | New York Yankees | 1b | Action - Batting | Swing Follow-Through |
| 2010 | Topps | | 263 | Placido Polanco | | player cards | Detroit Tigers | 2b | Action - Batting | Batting contact |
| 2010 | Topps | | 268 | Juan Pierre | | player cards | Los Angeles Dodgers | of | Action - Sliding | Head-first Slide,Sliding |
| 2010 | Topps | | 275 | Chris Coghlan | NL Rookie of the Year | player cards | Florida Marlins | of | Action - Baserunning | Rookie of the Year,Award Winner |
| 2010 | Topps | | 289 | Lyle Overbay | | player cards | Toronto Blue Jays | 1b | Action - Batting | |
| 2010 | Topps | | 311 | Jose Valverde | | player cards | Houston Astros | p | Action - Pitching | Batter view,Umpire |
| 2010 | Topps | | 325 | Julio Lugo | | player cards | St. Louis Cardinals | ss | Candid - Throwing | |
| 2010 | Topps | | 329 | | Franchise History | player cards | Colorado Rockies | | Stadium | Franchise History |
| 2010 | Topps | | 331 | Ryan Braun | | player cards | Milwaukee Brewers | of | Action - Fielding | Sliding catch,Catching ball |
| 2010 | Topps | | 335 | Jordan Norberto | RC | player cards | Arizona Diamondbacks | p | Pose - Looking at Camera | RC |
| 2010 | Topps | | 336 | C.J. Wilson | | player cards | Texas Rangers | p | Action - Pitching | Leg kick,Ad-Budweiser |
| 2010 | Topps | | 337 | Carlos Zambrano | | player cards | Chicago Cubs | p | Action - Pitching | |
| 2010 | Topps | | 338 | Brett Cecil | | player cards | Toronto Blue Jays | p | Action - Pitching | |
| 2010 | Topps | | 339 | Jose Reyes | | player cards | New York Mets | shortstop | Action - Sliding | Head-first Slide,Umpire |
| 2010 | Topps | | 340 | John Buck | | player cards | Toronto Blue Jays | c | Action - Throwing | Catcher throwing |
| 2010 | Topps | | 341 |
| Franchise History | player cards | Texas Rangers | | Celebration | Franchise History,Arm raised |
| 2010 | Topps | | 343 | Brian Bruney | | player cards | Washington Nationals | p | Action - Pitching | |
| 2010 | Topps | | 345 | Chris Volstad | | player cards | Florida Marlins | p | Action - Pitching | |
| 2010 | Topps | | 346 | Taylor Teagarden | | player cards | Texas Rangers | c | Action - Baserunning | Eye black |
| 2010 | Topps | | 347 | Aaron Harang | | player cards | Cincinnati Reds | p | Action - Pitching | |
| 2010 | Topps | | 348 | Jordan Zimmermann | | player cards | Washington Nationals | p | Action - Pitching | |
| 2010 | Topps | | 349 | Felix Pie | | player cards | Baltimore Orioles | of | Action - Baserunning | |
| 2010 | Topps | | 355 | James Russell | RC | player cards | Chicago Cubs | p | Pose - Pitching | RC |
| 2010 | Topps | | 370 | Robinson Cano | | player cards | New York Yankees | 2b | Action - Throwing | In air |
| 2010 | Topps | | 379 | Phil Hughes | | player cards | New York Yankees | p | Action - Pitching | |
| 2010 | Topps | | 382 | Kyle Davies | | player cards | Kansas City Royals | p | Action - Pitching | |
| 2010 | Topps | | 389 | Troy Tulowitzki | | player cards | Colorado Rockies | ss | Action - Throwing | Leaping,Sunglasses |
| 2010 | Topps | | 394 | Luis Castillo | | player cards | New York Mets | 2b | Action - Throwing | Throwing from knees |
| 2010 | Topps | | 413 | J.J. Hardy | | player cards | Minnesota Twins | ss | Action - Batting | |
| 2010 | Topps | | 424 | David Herndon | RC | player cards | Philadelphia Phillies | p | Pose - Looking at Camera | RC,Pitch grip |
| 2010 | Topps | | 436 |
| Team Card | player cards | New York Mets | | Candid - Teammates | Team Card,Team lineup |
| 2010 | Topps | | 453 | Jesse English | RC | player cards | Washington Nationals | p | Pose - Set Position | RC |
| 2010 | Topps | | 459 | Joel Zumaya | | player cards | Detroit Tigers | p | Action - Pitching | |
| 2010 | Topps | | 465 | Chien-Ming Wang | | player cards | Washington Nationals | p | Action - Pitching | |
| 2010 | Topps | | 471 | Drew Butera | RC | player cards | Minnesota Twins | c | Pose - Catching | RC,Crouched catcher |
| 2010 | Topps | | 475 | Johnny Damon | | player cards | Detroit Tigers | of | Action - Baserunning | Dropping bat |
| 2010 | Topps | | 479 | Chris Carpenter | | player cards | St. Louis Cardinals | p | Action - Pitching | |
| 2010 | Topps | | 486 | Raul Ibanez | | player cards | Philadelphia Phillies | of | Action - Fielding | Diving,Catching ball |
| 2010 | Topps | | 490 | Michael Bourn | | player cards | Houston Astros | of | Pose - Bunting | |
| 2010 | Topps | | 507 | Francisco Rodriguez | | player cards | New York Mets | p | Action - Pitching | |
| 2010 | Topps | | 529 | Carlos Lee | | player cards | Houston Astros | of | Action - Batting | Eye black |
| 2010 | Topps | | 533 | Gary Matthews Jr. | | player cards | New York Mets | of | Action - Fielding | Scoreboard,Sunglasses,Tracking flyball,Calling for ball |
| 2010 | Topps | | 538 | Travis Hafner | | player cards | Cleveland Indians | dh | Candid - Swinging bat | |
| 2010 | Topps | | 542 | Heath Bell | | player cards | San Diego Padres | p | Action - Pitching | |
| 2010 | Topps | | 558 | Ronny Paulino | | player cards | Florida Marlins | c | Action - Batting | |
| 2010 | Topps | | 559 | Nick Markakis | | player cards | Baltimore Orioles | of | Action - Sliding | Sliding,Sunglasses |
| 2010 | Topps | | 571 | Brandon Lyon | | player cards | Houston Astros | p | Action - Pitching | |
| 2010 | Topps | | 598 | Alberto Callaspo | | player cards | Kansas City Royals | 2b | Action - Throwing | Double play,Leaping |
| 2010 | Topps | | 609 | Jeff Suppan | | player cards | Milwaukee Brewers | p | Action - Pitching | |
| 2010 | Topps | | 614 | Kelly Johnson | | player cards | Arizona Diamondbacks | 2b | Action - Fielding | |
| 2010 | Topps | | 624 | Carlos Beltran | | player cards | New York Mets | of | Candid - Batting | Waving bat |
| 2010 | Topps | | 625 | Grady Sizemore | | player cards | Cleveland Indians | of | Action - Fielding | Catching ball,Scoreboard |
| 2010 | Topps | | 635 | Carl Pavano | | player cards | Minnesota Twins | p | Action - Pitching | |
| 2010 | Topps | | 643 | Michael Young | | player cards | Texas Rangers | 3b | Action - Fielding | Fielding grounder,Sunglasses,Ad-Yahoo |
| 2010 | Topps | | 644 | David Purcey | | player cards | Toronto Blue Jays | p | Action - Pitching | |
| 98 record(s) |