| team | player | lineup | pos | age | season | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | bavg | obp | slg | ops | career | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | bavg | obp | slg | ops |
| CHA | Pablo Ozuna | 1 | lf | 32.011 | season | 84 | 159 | 22 | 54 | 9 | 2 | 2 | 17 | 1 | 5 | 5 | 16 | .340 | .371 | .459 | .830 | career | 219 | 473 | 60 | 139 | 20 | 6 | 2 | 33 | 19 | 11 | 15 | 53 | .294 | .329 | .374 | .703 |
| CHA | Tadahito Iguchi | 2 | 2b | 31.275 | season | 118 | 487 | 82 | 138 | 19 | 0 | 14 | 56 | 8 | 2 | 45 | 96 | .283 | .346 | .409 | .755 | career | 253 | 998 | 156 | 280 | 44 | 6 | 29 | 127 | 23 | 6 | 92 | 210 | .281 | .344 | .424 | .768 |
| CHA | Joe Crede | 3 | 3b | 28.132 | season | 133 | 487 | 72 | 146 | 30 | 0 | 29 | 91 | 0 | 1 | 20 | 51 | .300 | .331 | .540 | .871 | career | 637 | 2209 | 292 | 585 | 119 | 3 | 103 | 342 | 4 | 5 | 122 | 327 | .265 | .309 | .461 | .771 |
| CHA | Jim Thome | 4 | dh | 36.009 | season | 121 | 422 | 96 | 123 | 22 | 0 | 38 | 95 | 0 | 0 | 86 | 124 | .291 | .413 | .614 | 1.027 | career | 1857 | 6341 | 1247 | 1788 | 346 | 24 | 468 | 1288 | 18 | 11 | 1343 | 1886 | .282 | .409 | .566 | .974 |
| CHA | Paul Konerko | 5 | 1b | 30.184 | season | 132 | 491 | 86 | 150 | 27 | 0 | 30 | 97 | 1 | 0 | 55 | 94 | .305 | .378 | .544 | .922 | career | 1255 | 4486 | 666 | 1265 | 223 | 5 | 240 | 789 | 5 | 1 | 455 | 703 | .282 | .352 | .494 | .847 |
| CHA | A.J. Pierzynski | 6 | c | 29.249 | season | 123 | 447 | 58 | 130 | 19 | 0 | 13 | 52 | 0 | 0 | 19 | 59 | .291 | .331 | .421 | .751 | career | 812 | 2806 | 348 | 806 | 174 | 14 | 68 | 378 | 6 | 9 | 121 | 347 | .287 | .330 | .432 | .762 |
| CHA | Brian Anderson | 7 | cf | 24.178 | season | 127 | 309 | 43 | 70 | 19 | 1 | 7 | 32 | 4 | 4 | 29 | 78 | .227 | .299 | .362 | .661 | career | 140 | 343 | 46 | 76 | 20 | 1 | 9 | 35 | 5 | 4 | 29 | 90 | .222 | .288 | .364 | .652 |
| CHA | Juan Uribe | 8 | ss | 27.167 | season | 115 | 396 | 43 | 93 | 24 | 2 | 16 | 60 | 0 | 1 | 13 | 68 | .235 | .261 | .427 | .688 | career | 709 | 2534 | 329 | 654 | 137 | 32 | 79 | 340 | 32 | 20 | 138 | 476 | .258 | .299 | .431 | .729 |
| CHA | Ryan Sweeney | 9 | rf-cf | 21.197 | season | 5 | 3 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | .667 | .667 | .667 | 1.333 | career | 5 | 3 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | .667 | .667 | .667 | 1.333 |
| CHA | Ross Gload | 7 | ph-rf | 30.153 | season | 75 | 127 | 17 | 41 | 6 | 1 | 2 | 16 | 3 | 0 | 6 | 12 | .323 | .356 | .433 | .789 | career | 257 | 465 | 55 | 137 | 25 | 2 | 11 | 72 | 3 | 3 | 34 | 75 | .295 | .343 | .428 | .771 |
| CHA | Alex Cintron | 8 | ph-ss | 27.262 | season | 80 | 246 | 32 | 67 | 7 | 3 | 4 | 34 | 8 | 3 | 9 | 32 | .272 | .301 | .374 | .675 | career | 519 | 1670 | 205 | 465 | 89 | 19 | 29 | 186 | 14 | 9 | 93 | 170 | .278 | .317 | .407 | .724 |
| team | player | lineup | pos | age | season | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | bavg | obp | slg | ops | career | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | bavg | obp | slg | ops |
| BOS | Kevin Youkilis | 1 | 1b | 27.174 | season | 132 | 513 | 91 | 146 | 36 | 1 | 13 | 65 | 5 | 1 | 81 | 105 | .285 | .385 | .435 | .820 | career | 248 | 800 | 140 | 222 | 54 | 1 | 21 | 109 | 5 | 2 | 128 | 169 | .278 | .382 | .426 | .808 |
| BOS | Mark Loretta | 2 | 2b | 35.022 | season | 132 | 552 | 64 | 162 | 29 | 0 | 4 | 51 | 3 | 1 | 42 | 56 | .293 | .353 | .368 | .720 | career | 1362 | 4827 | 659 | 1447 | 259 | 20 | 67 | 517 | 44 | 20 | 455 | 506 | .300 | .364 | .403 | .767 |
| BOS | David Ortiz | 3 | dh | 30.291 | season | 129 | 488 | 99 | 139 | 25 | 1 | 47 | 121 | 1 | 0 | 92 | 102 | .285 | .399 | .629 | 1.028 | career | 1021 | 3596 | 606 | 1016 | 259 | 10 | 224 | 747 | 6 | 1 | 513 | 781 | .283 | .371 | .547 | .918 |
| BOS | Manny Ramirez | 4 | lf | 34.098 | season | 125 | 435 | 78 | 141 | 27 | 1 | 34 | 100 | 0 | 1 | 97 | 97 | .324 | .442 | .625 | 1.067 | career | 1812 | 6561 | 1257 | 2063 | 438 | 16 | 469 | 1514 | 34 | 23 | 1051 | 1446 | .314 | .411 | .601 | 1.012 |
| BOS | Trot Nixon | 5 | rf | 32.147 | season | 94 | 315 | 53 | 93 | 21 | 0 | 7 | 48 | 0 | 1 | 50 | 40 | .295 | .398 | .429 | .826 | career | 962 | 3219 | 541 | 903 | 201 | 28 | 132 | 519 | 28 | 11 | 444 | 605 | .281 | .369 | .483 | .852 |
| BOS | Mike Lowell | 6 | 3b | 32.193 | season | 133 | 493 | 66 | 142 | 40 | 1 | 17 | 67 | 2 | 0 | 39 | 51 | .288 | .342 | .477 | .819 | career | 1122 | 4062 | 544 | 1111 | 281 | 4 | 160 | 645 | 23 | 4 | 393 | 580 | .274 | .339 | .463 | .802 |
| BOS | Coco Crisp | 7 | cf | 26.308 | season | 98 | 380 | 53 | 99 | 18 | 2 | 7 | 29 | 19 | 4 | 29 | 61 | .261 | .315 | .374 | .688 | career | 513 | 2006 | 288 | 566 | 108 | 16 | 42 | 205 | 73 | 29 | 143 | 281 | .282 | .328 | .415 | .743 |
| BOS | Doug Mirabelli | 8 | c | 35.322 | season | 68 | 159 | 11 | 29 | 6 | 0 | 6 | 22 | 0 | 0 | 13 | 48 | .182 | .257 | .333 | .590 | career | 513 | 1318 | 151 | 308 | 74 | 2 | 53 | 187 | 3 | 0 | 152 | 363 | .234 | .320 | .414 | .733 |
| BOS | Alex Gonzalez | 9 | ss | 29.202 | season | 100 | 351 | 44 | 93 | 20 | 2 | 9 | 43 | 1 | 0 | 21 | 59 | .265 | .311 | .410 | .721 | career | 995 | 3572 | 407 | 881 | 203 | 25 | 90 | 418 | 24 | 11 | 191 | 731 | .247 | .293 | .393 | .686 |
| team | player | seq | role | age | season | w | l | g | gs | cg | sho | gf | sv | ip | h | r | er | hr | bb | so | era | whip | career | w | l | g | gs | cg | sho | gf | sv | ip | h | r | er | hr | bb | so | era | whip |
| CHA | Javier Vazquez | 1 | Starter | 30.042 | season | 11 | 9 | 28 | 27 | 1 | 0 | 0 | 0 | 170.2 | 176 | 91 | 91 | 19 | 49 | 138 | 4.80 | 1.32 | career | 100 | 102 | 285 | 283 | 20 | 7 | 1 | 0 | 1,814.0 | 1829 | 873 | 873 | 242 | 486 | 1556 | 4.33 | 1.28 |
| team | player | seq | role | age | season | w | l | g | gs | cg | sho | gf | sv | ip | h | r | er | hr | bb | so | era | whip | career | w | l | g | gs | cg | sho | gf | sv | ip | h | r | er | hr | bb | so | era | whip |
| BOS | Kason Gabbard | 1 | Starter | 24.150 | season | 1 | 3 | 5 | 3 | 0 | 0 | 1 | 0 | 18.1 | 19 | 8 | 8 | 0 | 10 | 11 | 3.93 | 1.58 | career | 1 | 3 | 5 | 3 | 0 | 0 | 1 | 0 | 18.0 | 19 | 8 | 8 | 0 | 10 | 11 | 4.00 | 1.61 |
| BOS | Mike Timlin | 2 | Reliever | 40.179 | season | 6 | 4 | 58 | 0 | 0 | 0 | 15 | 4 | 55.0 | 61 | 23 | 23 | 6 | 15 | 25 | 3.76 | 1.38 | career | 69 | 66 | 951 | 4 | 0 | 0 | 415 | 134 | 1,091.0 | 1045 | 426 | 426 | 101 | 343 | 804 | 3.51 | 1.27 |