| team | player | lineup | pos | age | season | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | bavg | obp | slg | ops | career | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | bavg | obp | slg | ops |
| TBA | Julio Lugo | 1 | ss | 30.191 | season | 22 | 83 | 13 | 24 | 7 | 0 | 1 | 4 | 8 | 0 | 1 | 13 | .289 | .306 | .410 | .716 | career | 820 | 3034 | 465 | 839 | 157 | 23 | 57 | 303 | 123 | 40 | 271 | 575 | .277 | .339 | .400 | .738 |
| TBA | Carl Crawford | 2 | lf | 24.294 | season | 48 | 183 | 32 | 55 | 6 | 2 | 4 | 21 | 19 | 3 | 14 | 23 | .301 | .352 | .421 | .773 | career | 570 | 2342 | 340 | 678 | 94 | 51 | 37 | 241 | 188 | 38 | 111 | 331 | .289 | .322 | .421 | .743 |
| TBA | Jonny Gomes | 3 | dh | 25.185 | season | 49 | 168 | 30 | 45 | 8 | 1 | 14 | 39 | 1 | 4 | 31 | 56 | .268 | .382 | .577 | .959 | career | 163 | 545 | 92 | 146 | 22 | 7 | 35 | 94 | 10 | 9 | 71 | 181 | .268 | .365 | .527 | .892 |
| TBA | Ty Wigginton | 4 | 2b | 28.227 | season | 46 | 175 | 19 | 47 | 8 | 0 | 11 | 37 | 1 | 0 | 11 | 40 | .269 | .307 | .503 | .810 | career | 449 | 1513 | 193 | 397 | 91 | 9 | 52 | 217 | 22 | 3 | 124 | 295 | .262 | .322 | .438 | .759 |
| TBA | Toby Hall | 5 | c | 30.217 | season | 43 | 146 | 12 | 41 | 10 | 0 | 6 | 16 | 0 | 2 | 5 | 10 | .281 | .312 | .473 | .784 | career | 565 | 1975 | 191 | 528 | 109 | 1 | 42 | 244 | 2 | 7 | 90 | 173 | .267 | .304 | .387 | .691 |
| TBA | Aubrey Huff | 6 | 3b | 29.157 | season | 27 | 91 | 9 | 15 | 2 | 1 | 1 | 8 | 0 | 0 | 14 | 11 | .165 | .274 | .242 | .515 | career | 763 | 2889 | 383 | 820 | 159 | 9 | 121 | 429 | 20 | 9 | 237 | 398 | .284 | .340 | .471 | .811 |
| TBA | Damon Hollins | 7 | rf | 31.348 | season | 46 | 133 | 15 | 33 | 9 | 0 | 5 | 8 | 2 | 1 | 6 | 21 | .248 | .281 | .429 | .709 | career | 181 | 512 | 63 | 129 | 28 | 1 | 18 | 61 | 10 | 2 | 29 | 91 | .252 | .292 | .416 | .708 |
| TBA | Travis Lee | 8 | 1b | 31.000 | season | 50 | 136 | 11 | 27 | 6 | 0 | 4 | 11 | 1 | 1 | 11 | 35 | .199 | .262 | .331 | .593 | career | 1035 | 3533 | 452 | 908 | 186 | 14 | 108 | 468 | 55 | 13 | 426 | 666 | .257 | .336 | .409 | .745 |
| TBA | Joey Gathright | 9 | cf | 25.029 | season | 47 | 126 | 23 | 25 | 4 | 0 | 0 | 7 | 10 | 3 | 19 | 25 | .198 | .313 | .230 | .543 | career | 142 | 381 | 63 | 94 | 11 | 3 | 0 | 21 | 33 | 8 | 31 | 78 | .247 | .315 | .291 | .606 |
| team | player | lineup | pos | age | season | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | bavg | obp | slg | ops | career | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | bavg | obp | slg | ops |
| BOS | Willie Harris | 8 | cf | 27.338 | season | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | career | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||||||
| BOS | Kevin Youkilis | 1 | 1b | 27.072 | season | 43 | 167 | 33 | 53 | 13 | 1 | 5 | 24 | 1 | 0 | 32 | 36 | .317 | .431 | .497 | .928 | career | 159 | 454 | 82 | 129 | 31 | 1 | 13 | 68 | 1 | 1 | 79 | 100 | .284 | .397 | .443 | .839 |
| BOS | Mark Loretta | 2 | 2b | 34.285 | season | 46 | 191 | 24 | 58 | 10 | 0 | 1 | 21 | 2 | 1 | 15 | 11 | .304 | .357 | .372 | .729 | career | 1276 | 4466 | 619 | 1343 | 240 | 20 | 64 | 487 | 43 | 20 | 428 | 461 | .301 | .365 | .406 | .771 |
| BOS | David Ortiz | 3 | dh | 30.189 | season | 46 | 180 | 29 | 49 | 11 | 0 | 14 | 46 | 0 | 0 | 23 | 37 | .272 | .354 | .567 | .921 | career | 938 | 3288 | 536 | 926 | 245 | 9 | 191 | 672 | 5 | 1 | 444 | 716 | .282 | .366 | .536 | .902 |
| BOS | Manny Ramirez | 4 | lf | 33.361 | season | 46 | 161 | 27 | 50 | 6 | 1 | 11 | 29 | 0 | 0 | 36 | 42 | .311 | .435 | .565 | 1.000 | career | 1733 | 6287 | 1206 | 1972 | 417 | 16 | 446 | 1443 | 34 | 22 | 990 | 1391 | .314 | .410 | .598 | 1.007 |
| BOS | Jason Varitek | 5 | c | 34.045 | season | 41 | 135 | 21 | 32 | 6 | 1 | 4 | 21 | 1 | 1 | 20 | 20 | .237 | .333 | .385 | .719 | career | 1006 | 3313 | 454 | 897 | 218 | 9 | 123 | 509 | 24 | 13 | 380 | 713 | .271 | .350 | .453 | .803 |
| BOS | Mike Lowell | 6 | 3b | 32.091 | season | 43 | 168 | 29 | 56 | 22 | 1 | 7 | 29 | 1 | 0 | 15 | 15 | .333 | .386 | .601 | .987 | career | 1032 | 3737 | 507 | 1025 | 263 | 4 | 150 | 607 | 22 | 4 | 369 | 544 | .274 | .341 | .467 | .808 |
| BOS | Trot Nixon | 7 | rf | 32.045 | season | 41 | 133 | 27 | 40 | 8 | 0 | 3 | 22 | 0 | 0 | 25 | 15 | .301 | .420 | .429 | .848 | career | 909 | 3037 | 515 | 850 | 188 | 28 | 128 | 493 | 28 | 10 | 419 | 580 | .280 | .368 | .487 | .855 |
| BOS | Wily Mo Pena | 8 | cf | 24.123 | season | 37 | 112 | 12 | 36 | 6 | 0 | 4 | 18 | 0 | 0 | 10 | 37 | .321 | .370 | .482 | .852 | career | 339 | 942 | 120 | 242 | 39 | 2 | 55 | 152 | 8 | 3 | 64 | 325 | .257 | .312 | .478 | .789 |
| BOS | Alex Gonzalez | 9 | ss | 29.100 | season | 40 | 128 | 13 | 29 | 6 | 0 | 2 | 14 | 1 | 0 | 12 | 23 | .227 | .297 | .320 | .617 | career | 935 | 3349 | 376 | 817 | 189 | 23 | 83 | 389 | 24 | 11 | 182 | 695 | .244 | .291 | .388 | .680 |
| team | player | seq | role | age | season | w | l | g | gs | cg | sho | gf | sv | ip | h | r | er | hr | bb | so | era | whip | career | w | l | g | gs | cg | sho | gf | sv | ip | h | r | er | hr | bb | so | era | whip |
| TBA | Scott Kazmir | 1 | Starter | 22.122 | season | 7 | 3 | 11 | 11 | 0 | 0 | 0 | 0 | 69.1 | 69 | 23 | 22 | 7 | 23 | 73 | 2.86 | 1.33 | career | 19 | 15 | 51 | 50 | 0 | 0 | 0 | 0 | 289.0 | 274 | 122 | 121 | 23 | 143 | 288 | 3.77 | 1.44 |
| TBA | Brian Meadows | 2 | Reliever | 30.186 | season | 1 | 0 | 11 | 0 | 0 | 0 | 3 | 0 | 15.1 | 23 | 11 | 11 | 2 | 4 | 8 | 6.46 | 1.76 | career | 45 | 56 | 294 | 122 | 3 | 0 | 38 | 2 | 906.0 | 1079 | 510 | 510 | 127 | 248 | 427 | 5.07 | 1.46 |
| TBA | Chad Orvella | 3 | Reliever | 25.237 | season | 1 | 4 | 14 | 0 | 0 | 0 | 4 | 0 | 16.0 | 21 | 11 | 11 | 2 | 15 | 14 | 6.19 | 2.25 | career | 4 | 7 | 51 | 0 | 0 | 0 | 13 | 1 | 66.0 | 68 | 31 | 31 | 6 | 37 | 57 | 4.23 | 1.59 |
| team | player | seq | role | age | season | w | l | g | gs | cg | sho | gf | sv | ip | h | r | er | hr | bb | so | era | whip | career | w | l | g | gs | cg | sho | gf | sv | ip | h | r | er | hr | bb | so | era | whip |
| BOS | David Wells | 1 | Starter | 43.006 | season | 0 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 8.1 | 15 | 8 | 8 | 4 | 1 | 1 | 8.64 | 1.92 | career | 227 | 144 | 620 | 449 | 54 | 12 | 65 | 13 | 3,215.0 | 3352 | 1454 | 1454 | 378 | 667 | 2082 | 4.07 | 1.25 |
| BOS | Julian Tavarez | 2 | Reliever | 33.004 | season | 1 | 0 | 19 | 0 | 0 | 0 | 1 | 0 | 21.1 | 25 | 11 | 11 | 3 | 6 | 13 | 4.64 | 1.45 | career | 73 | 55 | 661 | 79 | 1 | 0 | 148 | 21 | 1,103.0 | 1197 | 531 | 531 | 86 | 419 | 639 | 4.33 | 1.47 |
| BOS | Keith Foulke | 3 | Reliever | 33.219 | season | 2 | 1 | 24 | 0 | 0 | 0 | 9 | 0 | 26.2 | 27 | 14 | 14 | 5 | 3 | 20 | 4.73 | 1.13 | career | 40 | 34 | 568 | 8 | 0 | 0 | 390 | 190 | 733.0 | 599 | 267 | 267 | 83 | 177 | 679 | 3.28 | 1.06 |
| BOS | Rudy Seanez | 4 | Reliever | 37.218 | season | 0 | 0 | 16 | 0 | 0 | 0 | 7 | 0 | 18.2 | 21 | 11 | 11 | 4 | 8 | 21 | 5.30 | 1.55 | career | 27 | 20 | 396 | 0 | 0 | 0 | 111 | 11 | 412.0 | 362 | 191 | 191 | 42 | 209 | 438 | 4.17 | 1.39 |
| BOS | Jonathan Papelbon | 5 | Reliever | 25.184 | season | 0 | 1 | 24 | 0 | 0 | 0 | 22 | 17 | 25.0 | 12 | 1 | 1 | 0 | 3 | 23 | 0.36 | 0.60 | career | 3 | 2 | 41 | 3 | 0 | 0 | 26 | 17 | 59.0 | 45 | 11 | 11 | 4 | 20 | 57 | 1.68 | 1.10 |