| 2000 | ANA | Anaheim Angels | MLB-AL | MLB | team page | 162 | 82 | 80 | 9.5 | 864 | 869 | -5 | 3 | 8 | Mike Scioscia | Edison International Field | dnq |
| 2000 | ANA | Edmonton Trappers | PCL | AAA | team page | 141 | 63 | 78 | 26.0 | 695 | 774 | -79 | 3 | 12 | Garry Templeton | Telus Field | dnq |
| 2000 | ANA | Erie SeaWolves | East | AA | team page | 141 | 47 | 94 | 37.5 | 581 | 757 | -176 | 6 | 12 | Don Wakamatsu | Jerry Uht Park | dnq |
| 2000 | ANA | Lake Elsinore Storm | Calif | A+ | team page | 140 | 70 | 70 | 19.0 | 770 | 748 | 22 | 3 | 6 | Mario Mendoza | Lake Elsinore Diamond | Lost in 1st Round |
| 2000 | ANA | Cedar Rapids Kernels | Midw | A | team page | 139 | 53 | 86 | -- | 588 | 747 | -159 | 0 | 13 | Tyrone Boykin, Mitch Seoane | Veterans Field | dnq |
| 2000 | ANA | Boise Hawks | Nwst | A- | team page | 76 | 41 | 35 | -- | 440 | 441 | -1 | 1 | 2 | Tom Kotchman | Memorial Stadium | dnq |
| 2000 | ANA | Butte Copper Kings | Pio | Rk | team page | 76 | 29 | 47 | 17.0 | 486 | 591 | -105 | 4 | 7 | Joe Urso | Alumni Coliseum | dnq |
| 2000 | ARI | Arizona Diamondbacks | MLB-NL | MLB | team page | 162 | 85 | 77 | 12.0 | 792 | 754 | 38 | 3 | 7 | Buck Showalter | Bank One Ballpark | dnq |
| 2000 | ARI | Tucson Sidewinders | PCL | AAA | team page | 141 | 68 | 73 | 20.5 | 752 | 746 | 6 | 3 | 9 | Tom Spencer | Tucson Electric Park | dnq |
| 2000 | ARI | El Paso Diablos | Tex | AA | team page | 140 | 74 | 66 | 9.0 | 759 | 740 | 19 | 3 | 3 | Bobby Dickerson | Cohen Stadium | Lost in Semi-Finals |
| 2000 | ARI | High Desert Mavericks | Calif | A+ | team page | 140 | 48 | 92 | 41.0 | 738 | 987 | -249 | 5 | 10 | Scott Coolbaugh | Mavericks Stadium | dnq |
| 2000 | ARI | South Bend Silver Hawks | Midw | A | team page | 138 | 60 | 78 | -- | 653 | 659 | -6 | 0 | 12 | | Stanley Covelski Regional Stadium | dnq |
| 2000 | ARI | Arizona Diamondbacks | Ariz | Rk | team page | 54 | 27 | 27 | -- | 314 | 358 | -44 | 0 | 5 | Joe Almaraz | Tucson Electric Park | dnq |
| 2000 | ARI | Missoula Osprey | Pio | Rk | team page | 76 | 44 | 32 | -- | 429 | 396 | 33 | 1 | 2 | Chip Hale | Lindborg-Cregg Field | dnq |
| 2000 | ATL | Atlanta Braves | MLB-NL | MLB | team page | 162 | 95 | 67 | -- | 810 | 714 | 96 | 1 | 2 | Bobby Cox | Turner Field | Lost in 1st Round (Cardinals) |
| 2000 | ATL | Richmond Braves | IL | AAA | team page | 143 | 51 | 92 | 30.0 | 626 | 782 | -156 | 4 | 14 | Randy Ingle | The Diamond | dnq |
| 2000 | ATL | Greenville Braves | Sou | AA | team page | 139 | 68 | 71 | 2.5 | 565 | 581 | -16 | 3 | 6 | Paul Runge | Greenville Municipal Stadium | Lost in Semi-Finals |
| 2000 | ATL | Myrtle Beach Pelicans | Caro | A+ | team page | 140 | 88 | 52 | -- | 567 | 395 | 172 | 1 | 1 | Brian Snitker | BB&T Coastal Field | League Champions |
| 2000 | ATL | Macon Braves | SAL | A | team page | 139 | 69 | 70 | -- | 626 | 613 | 13 | 0 | 7 | Jeff Treadway | Luther Williams Field | dnq |
| 2000 | ATL | Jamestown Jammers | NYPL | A- | team page | 75 | 37 | 38 | 10.5 | 383 | 367 | 16 | 3 | 8 | Jim Saul | Russell Diethrick Park | dnq |
| 2000 | ATL | Danville Braves | App | Rk | team page | 66 | 37 | 29 | -- | 341 | 294 | 47 | 1 | 3 | Joe Cannon | American Legion Field | Lost in Finals |
| 2000 | ATL | Gulf Coast Braves | GCL | Rk | team page | 60 | 26 | 34 | 14.0 | 251 | 263 | -12 | 3 | 10 | Rick Albert | Cracker Jack Stadium | dnq |
| 2000 | BAL | Baltimore Orioles | MLB-AL | MLB | team page | 162 | 74 | 88 | 13.5 | 794 | 913 | -119 | 4 | 11 | Mike Hargrove | Oriole Park at Camden Yards | dnq |
| 2000 | BAL | Rochester Red Wings | IL | AAA | team page | 144 | 65 | 79 | 20.5 | 622 | 675 | -53 | 5 | 10 | Marv Foley | Frontier Field | dnq |
| 2000 | BAL | Bowie Baysox | East | AA | team page | 142 | 65 | 77 | 20.0 | 664 | 676 | -12 | 5 | 10 | Andy Etchebarren | Prince George's Stadium | dnq |
| 2000 | BAL | Frederick Keys | Caro | A+ | team page | 137 | 66 | 71 | -- | 658 | 658 | 0 | 1 | 5 | Dave Machemer | Harry Grove Stadium | Lost in Semi-Finals |
| 2000 | BAL | Delmarva Shorebirds | SAL | A | team page | 136 | 74 | 62 | -- | 700 | 603 | 97 | 0 | 3 | Joe Ferguson | Arthur W. Perdue Stadium | League Champions |
| 2000 | BAL | Bluefield Orioles | App | Rk | team page | 63 | 31 | 32 | 4.5 | 344 | 379 | -35 | 3 | 7 | Duffy Dyer | Bowen Field at Peters Park | dnq |
| 2000 | BAL | Gulf Coast Orioles | GCL | Rk | team page | 56 | 25 | 31 | 13.0 | 266 | 307 | -41 | 4 | 9 | Jesus Alfaro | Ed Smith Stadium | dnq |
| 2000 | BOS | Boston Red Sox | MLB-AL | MLB | team page | 162 | 85 | 77 | 2.5 | 792 | 745 | 47 | 2 | 6 | Jimy Williams | Fenway Park | dnq |
| 2000 | BOS | Pawtucket Red Sox | IL | AAA | team page | 143 | 82 | 61 | 3.0 | 713 | 637 | 76 | 3 | 3 | Gary Jones | McCoy Stadium | dnq |
| 2000 | BOS | Trenton Thunder | East | AA | team page | 142 | 67 | 75 | 16.0 | 691 | 698 | -7 | 5 | 9 | Billy Gardner | Mercer County Waterfront Park | dnq |
| 2000 | BOS | Sarasota Red Sox | FSL | A+ | team page | 139 | 60 | 79 | -- | 596 | 684 | -88 | 0 | 12 | | Ed Smith Stadium | dnq |
| 2000 | BOS | Augusta GreenJackets | SAL | A | team page | 141 | 83 | 58 | -- | 692 | 607 | 85 | 0 | 2 | Mike Boulanger | Lake Olmstead Stadium | Lost in Semi-Finals |
| 2000 | BOS | Lowell Spinners | NYPL | A- | team page | 75 | 41 | 34 | 5.0 | 292 | 290 | 2 | 4 | 5 | Arnold Beyeler | Edward A. LeLacheur Park | dnq |
| 2000 | BOS | Gulf Coast Red Sox | GCL | Rk | team page | 55 | 29 | 26 | 8.5 | 297 | 268 | 29 | 3 | 7 | John Sanders | City of Palms Park | dnq |
| 2000 | CHN | Chicago Cubs | MLB-NL | MLB | team page | 162 | 65 | 97 | 30.0 | 764 | 904 | -140 | 6 | 16 | Don Baylor | Wrigley Field | dnq |
| 2000 | CHN | Iowa Cubs | PCL | AAA | team page | 144 | 57 | 87 | 29.0 | 715 | 836 | -121 | 4 | 16 | Dave Trembley | Sec Taylor Stadium II | dnq |
| 2000 | CHN | West Tennessee Diamond Jaxx | Sou | AA | team page | 138 | 80 | 58 | -- | 609 | 493 | 116 | 1 | 1 | Dave Bialas | Pringles Park | League Champions |
| 2000 | CHN | Daytona Cubs | FSL | A+ | team page | 139 | 76 | 63 | -- | 696 | 615 | 81 | 0 | 5 | Joey Cora | Jackie Robinson Ballpark | dnq |
| 2000 | CHN | Lansing Lugnuts | Midw | A | team page | 138 | 70 | 68 | -- | 642 | 678 | -36 | 0 | 8 | Steve McFarland | Oldsmobile Park | dnq |
| 2000 | CHN | Eugene Emeralds | Nwst | A- | team page | 76 | 40 | 36 | -- | 340 | 314 | 26 | 1 | 3 | Danny Sheaffer | Civic Stadium | Lost in Finals |
| 2000 | CHN | Arizona Cubs | Ariz | Rk | team page | 56 | 32 | 24 | -- | 371 | 344 | 27 | 0 | 3 | Carmelo Martinez | Fitch Park | dnq |
| 2000 | CHA | Chicago White Sox | MLB-AL | MLB | team page | 162 | 95 | 67 | -- | 978 | 839 | 139 | 1 | 1 | Jerry Manuel | Comiskey Park II | Lost in 1st Round (Mariners) |
| 2000 | CHA | Charlotte Knights | IL | AAA | team page | 143 | 78 | 65 | 3.0 | 644 | 605 | 39 | 2 | 6 | Nick Leyva | Knights Stadium | dnq |
| 2000 | CHA | Birmingham Barons | Sou | AA | team page | 140 | 77 | 63 | 4.0 | 629 | 547 | 82 | 2 | 2 | Nick Capra | Hoover Metropolitan Stadium | Lost in Semi-Finals |
| 2000 | CHA | Winston-Salem Warthogs | Caro | A+ | team page | 139 | 68 | 71 | 19.5 | 630 | 673 | -43 | 4 | 4 | Brian Dayett | Ernie Shore Field | dnq |
| 2000 | CHA | Burlington Bees | Midw | A | team page | 139 | 51 | 88 | -- | 542 | 718 | -176 | 0 | 14 | Jerry Terrell | Community Field | dnq |
| 2000 | CHA | Bristol White Sox | App | Rk | team page | 67 | 34 | 33 | 13.5 | 319 | 311 | 8 | 4 | 5 | R.J. Reynolds | Devault Memorial Stadium | dnq |
| 2000 | CIN | Cincinnati Reds | MLB-NL | MLB | team page | 162 | 85 | 77 | 10.0 | 825 | 765 | 60 | 2 | 6 | Jack McKeon | Cinergy Field | dnq |
| 2000 | CIN | Louisville RiverBats | IL | AAA | team page | 144 | 71 | 73 | 10.0 | 748 | 698 | 50 | 3 | 9 | Dave Miley | Louisville Slugger Field | dnq |
| 2000 | CIN | Chattanooga Lookouts | Sou | AA | team page | 138 | 70 | 68 | 10.0 | 646 | 617 | 29 | 3 | 3 | Mike Rojas | BellSouth Park | dnq |
| 2000 | CIN | Clinton LumberKings | Midw | A | team page | 140 | 71 | 69 | -- | 655 | 641 | 14 | 0 | 9 | Jay Sorg | Riverview Stadium | dnq |
| 2000 | CIN | Dayton Dragons | Midw | A | team page | 137 | 70 | 67 | -- | 730 | 716 | 14 | 0 | 7 | Freddie Benavides | Fifth Third Field | dnq |
| 2000 | CIN | Billings Mustangs | Pio | Rk | team page | 75 | 39 | 36 | 6.5 | 513 | 504 | 9 | 3 | 5 | Russ Nixon | Cobb Field | dnq |
| 2000 | CIN | Gulf Coast Reds | GCL | Rk | team page | 55 | 14 | 41 | 23.5 | 188 | 350 | -162 | 5 | 13 | Luis Quinones | Ed Smith Stadium | dnq |
| 2000 | CLE | Cleveland Indians | MLB-AL | MLB | team page | 162 | 90 | 72 | 5.0 | 950 | 816 | 134 | 2 | 4 | Charlie Manuel | Jacobs Field | dnq |
| 2000 | CLE | Buffalo Bisons | IL | AAA | team page | 145 | 86 | 59 | -- | 743 | 654 | 89 | 1 | 1 | Joel Skinner | Dunn Tire Park | Lost in Semi-Finals |
| 2000 | CLE | Akron Aeros | East | AA | team page | 143 | 75 | 68 | 10.5 | 656 | 639 | 17 | 3 | 6 | Eric Wedge | Canal Park | dnq |
| 2000 | CLE | Kinston Indians | Caro | A+ | team page | 137 | 68 | 69 | 18.5 | 618 | 624 | -6 | 3 | 3 | Brad Komminsk | Grainger Stadium | dnq |
| 2000 | CLE | Columbus Red Stixx | SAL | A | team page | 137 | 67 | 70 | -- | 651 | 647 | 4 | 0 | 8 | Rick Gutierrez | Golden Park | Lost in Finals |
| 2000 | CLE | Mahoning Valley Scrappers | NYPL | A- | team page | 76 | 48 | 28 | -- | 432 | 328 | 104 | 1 | 1 | Ted Kubiak | Cafaro Field | Lost in Finals |
| 2000 | CLE | Burlington indians | App | Rk | team page | 67 | 21 | 46 | 16.5 | 282 | 416 | -134 | 5 | 10 | Dave Turgeon | Burlington Athletic Stadium | dnq |
| 2000 | COL | Colorado Rockies | MLB-NL | MLB | team page | 162 | 82 | 80 | 15.0 | 968 | 897 | 71 | 4 | 8 | Buddy Bell | Coors Field | dnq |
| 2000 | COL | Colorado Springs Sky Sox | PCL | AAA | team page | 142 | 74 | 68 | 11.0 | 823 | 811 | 12 | 2 | 6 | Chris Cron | Sky Sox Stadium | dnq |
| 2000 | COL | Carolina Mudcats | Sou | AA | team page | 139 | 64 | 75 | 6.5 | 570 | 605 | -35 | 5 | 10 | Ronnie Gideon | Five County Stadium | dnq |
| 2000 | COL | Salem Avalanche | Caro | A+ | team page | 140 | 73 | 67 | 15.0 | 654 | 615 | 39 | 2 | 2 | Alan Cockrell | Salem Memorial Baseball Stadium | dnq |
| 2000 | COL | Asheville Tourists | SAL | A | team page | 135 | 66 | 69 | -- | 560 | 605 | -45 | 0 | 9 | Joe Mikulik | McCormick Field | dnq |
| 2000 | COL | Portland Rockies | Nwst | A- | team page | 76 | 32 | 44 | 8.0 | 317 | 362 | -45 | 4 | 8 | Billy White | Civic Stadium | dnq |
| 2000 | COL | Arizona Rockies | Ariz | Rk | team page | 54 | 35 | 19 | -- | 417 | 271 | 146 | 0 | 2 | P.J. Carey | Hi Corbett Field | Lost in Finals |
| 2000 | DET | Detroit Tigers | MLB-AL | MLB | team page | 162 | 79 | 83 | 16.0 | 823 | 827 | -4 | 3 | 9 | Phil Garner | Comerica Park | dnq |
| 2000 | DET | Toledo Mud Hens | IL | AAA | team page | 141 | 55 | 86 | 24.5 | 657 | 808 | -151 | 4 | 12 | Dave Anderson, Glenn Ezell | Ned Skeldon Stadium | dnq |
| 2000 | DET | Jacksonville Suns | Sou | AA | team page | 140 | 69 | 71 | 2.0 | 594 | 634 | -40 | 2 | 5 | Gene Roof | Sam W. Wolfson Baseball Park | Lost in Finals |
| 2000 | DET | Lakeland Tigers | FSL | A+ | team page | 140 | 52 | 88 | -- | 589 | 708 | -119 | 0 | 14 | Skeeter Barnes | Joker Marchant Stadium | dnq |
| 2000 | DET | West Michigan Whitecaps | Midw | A | team page | 140 | 88 | 52 | -- | 685 | 502 | 183 | 0 | 1 | Bruce Fields | Fifth Third Ballpark | dnq |
| 2000 | DET | Oneonta Tigers | NYPL | A- | team page | 76 | 35 | 41 | 13.0 | 355 | 365 | -10 | 4 | 10 | Gary Green | Damaschke Field | dnq |
| 2000 | DET | Gulf Coast Tigers (East) | GCL | Rk | team page | 60 | 34 | 26 | 6.0 | 265 | 245 | 20 | 2 | 5 | Kevin Bradshaw | Joker Marchant Stadium | dnq |
| 2000 | MIA | Florida Marlins | MLB-NL | MLB | team page | 161 | 79 | 82 | 15.5 | 731 | 797 | -66 | 3 | 9 | John Boles | Pro Player Stadium | dnq |
| 2000 | MIA | Calgary Cannons | PCL | AAA | team page | 142 | 60 | 82 | 29.5 | 768 | 926 | -158 | 4 | 14 | Lynn Jones | Foothills Stadium | dnq |
| 2000 | MIA | Portland Sea Dogs | East | AA | team page | 141 | 71 | 70 | 11.5 | 736 | 714 | 22 | 4 | 8 | Rick Renteria | Hadlock Field | dnq |
| 2000 | MIA | Brevard County Manatees | FSL | A+ | team page | 140 | 66 | 74 | -- | 581 | 645 | -64 | 0 | 10 | Dave Huppert | USSSA Space Coast Complex | dnq |
| 2000 | MIA | Kane County Cougars | Midw | A | team page | 139 | 74 | 65 | -- | 586 | 571 | 15 | 0 | 4 | Russ Morman | Elfstrom Stadium | dnq |
| 2000 | MIA | Utica Blue Sox | NYPL | A- | team page | 75 | 35 | 40 | 12.5 | 361 | 365 | -4 | 5 | 9 | Jon Deeble | Donovan Stadium at Murnane Field | dnq |
| 2000 | MIA | Gulf Coast Marlins | GCL | Rk | team page | 60 | 40 | 20 | -- | 316 | 232 | 84 | 1 | 2 | Kevin Boles | USSSA Space Coast Complex | Lost in Semi-Finals |
| 2000 | HOU | Houston Astros | MLB-NL | MLB | team page | 162 | 72 | 90 | 23.0 | 938 | 944 | -6 | 4 | 12 | Larry Dierker | Enron Field | dnq |
| 2000 | HOU | New Orleans Zephyrs | PCL | AAA | team page | 142 | 68 | 74 | 14.0 | 633 | 688 | -55 | 3 | 10 | Tony Pena | Zephyr Field | dnq |
| 2000 | HOU | Round Rock Express | Tex | AA | team page | 140 | 83 | 57 | -- | 745 | 671 | 74 | 1 | 1 | Jackie Moore | Dell Diamond | League Champions |
| 2000 | HOU | Kissimmee Cobras | FSL | A+ | team page | 139 | 73 | 66 | -- | 627 | 605 | 22 | 0 | 6 | | Osceola County Stadium | dnq |
| 2000 | HOU | Michigan Battle Cats | Midw | A | team page | 138 | 82 | 56 | -- | 747 | 607 | 140 | 0 | 2 | Al Pedrique | C.O. Brown Stadium | dnq |
| 2000 | HOU | Auburn Doubledays | NYPL | A- | team page | 74 | 32 | 42 | 15.0 | 305 | 330 | -25 | 6 | 11 | John Massarelli | Falcon Park II | dnq |
| 2000 | HOU | Martinsville Astros | App | Rk | team page | 66 | 30 | 36 | 7.0 | 317 | 358 | -41 | 4 | 8 | Brad Wellman | Hooker Field | dnq |
| 2000 | KCA | Kansas City Royals | MLB-AL | MLB | team page | 162 | 77 | 85 | 18.0 | 879 | 930 | -51 | 4 | 10 | Tony Muser | Kauffman Stadium | dnq |
| 2000 | KCA | Omaha Golden Spikes | PCL | AAA | team page | 143 | 64 | 79 | 21.5 | 658 | 771 | -113 | 3 | 11 | John Mizerock | Johnny Rosenblatt Stadium | dnq |
| 2000 | KCA | Wichita Wranglers | Tex | AA | team page | 137 | 76 | 61 | 5.5 | 725 | 661 | 64 | 2 | 2 | Keith Bodie | Lawrence-Dumont Stadium | Lost in Finals |
| 2000 | KCA | Wilmington Blue Rocks | Caro | A+ | team page | 139 | 63 | 76 | 4.0 | 584 | 627 | -43 | 3 | 7 | Jeff Garber | Daniel S. Frawley Stadium | dnq |
| 2000 | KCA | Charleston (Wv) AlleyCats | SAL | A | team page | 133 | 53 | 80 | -- | 505 | 628 | -123 | 0 | 14 | Joe Szekely | Walt Powell Park | dnq |
| 2000 | KCA | Spokane Indians | Nwst | A- | team page | 76 | 38 | 38 | 3.0 | 389 | 347 | 42 | 3 | 5 | Tom Poquette | Avista Stadium | dnq |
| 2000 | KCA | Gulf Coast Royals | GCL | Rk | team page | 60 | 20 | 40 | 20.0 | 195 | 287 | -92 | 4 | 11 | Andre David, Ron Karkovice | Baseball City Stadium | dnq |
| 2000 | LAN | Los Angeles Dodgers | MLB-NL | MLB | team page | 162 | 86 | 76 | 11.0 | 798 | 729 | 69 | 2 | 5 | Davey Johnson | Dodger Stadium | dnq |
| 2000 | LAN | Albuquerque Dukes | PCL | AAA | team page | 144 | 86 | 58 | -- | 943 | 754 | 189 | 1 | 3 | Tom Gamboa | Albuquerque Sports Stadium | Lost in Semi-Finals |
| 2000 | LAN | San Antonio Missions | Tex | AA | team page | 140 | 64 | 76 | 19.0 | 612 | 707 | -95 | 6 | 7 | Rick Burleson | Nelson W. Wolff Municipal Stadium | dnq |
| 2000 | LAN | San Bernardino Stampede | Calif | A+ | team page | 140 | 77 | 63 | 12.0 | 713 | 604 | 109 | 2 | 4 | Dino Ebel | Arrowhead Credit Union Park | League Champions |
| 2000 | LAN | Vero Beach Dodgers | FSL | A+ | team page | 137 | 66 | 71 | -- | 661 | 752 | -91 | 0 | 8 | | Holman Stadium | dnq |
| 2000 | LAN | Yakima Bears | Nwst | A- | team page | 76 | 41 | 35 | -- | 326 | 322 | 4 | 2 | 1 | Butch Hughes | Yakima County Stadium | League Champions |
| 2000 | LAN | Great Falls Dodgers | Pio | Rk | team page | 76 | 42 | 34 | 2.0 | 394 | 416 | -22 | 2 | 3 | Juan Bustabad | Legion Field | Lost in Finals |
| 2000 | MIL | Milwaukee Brewers | MLB-NL | MLB | team page | 162 | 73 | 89 | 22.0 | 740 | 826 | -86 | 3 | 11 | Davey Lopes | County Stadium | dnq |
| 2000 | MIL | Indianapolis Indians | IL | AAA | team page | 144 | 81 | 63 | -- | 704 | 644 | 60 | 1 | 5 | Steve Smith | Victory Field | League Champions |
| 2000 | MIL | Huntsville Stars | Sou | AA | team page | 139 | 64 | 75 | 16.5 | 603 | 647 | -44 | 5 | 9 | Carlos Lezcano | Joe W. Davis Stadium | dnq |
| 2000 | MIL | Mudville Nine | Calif | A+ | team page | 140 | 68 | 72 | -- | 604 | 638 | -34 | 4 | 7 | Lonnie Keeter, Barry Moss | Billy Hebert Field | dnq |
| 2000 | MIL | Beloit Snappers | Midw | A | team page | 135 | 71 | 64 | -- | 594 | 586 | 8 | 0 | 5 | Don Money | Harry C. Pohlman Field | dnq |
| 2000 | MIL | Helena Raptors | Pio | Rk | team page | 76 | 26 | 50 | 18.0 | 377 | 513 | -136 | 4 | 8 | Dan Norman | Kindrick Field | dnq |
| 2000 | MIL | Ogden Raptors | Pio | Rk | team page | 75 | 41 | 34 | 4.5 | 531 | 456 | 75 | 2 | 4 | Ed Sedar | Lindquist Field | Lost in Semi-Finals |
| 2000 | MIN | Minnesota Twins | MLB-AL | MLB | team page | 162 | 69 | 93 | 26.0 | 748 | 880 | -132 | 5 | 14 | Tom Kelly | Hubert H. Humphrey Metrodome | dnq |
| 2000 | MIN | Salt Lake Buzz | PCL | AAA | team page | 143 | 90 | 53 | -- | 1016 | 795 | 221 | 1 | 1 | Phil Roof | Franklin Covey Field | Lost in Finals |
| 2000 | MIN | New Britain Rock Cats | East | AA | team page | 142 | 51 | 91 | 32.0 | 631 | 793 | -162 | 6 | 11 | John Russell | New Britain Stadium | dnq |
| 2000 | MIN | Fort Myers Miracle | FSL | A+ | team page | 140 | 83 | 57 | -- | 641 | 536 | 105 | 0 | 2 | Jose Marzan | Hammond Stadium | dnq |
| 2000 | MIN | Quad Cities River Bandits | Midw | A | team page | 139 | 64 | 75 | -- | 581 | 620 | -39 | 0 | 10 | Stan Cliburn | John O'Donnell Stadium | dnq |
| 2000 | MIN | Elizabethton Twins | App | Rk | team page | 64 | 46 | 18 | -- | 378 | 279 | 99 | 1 | 1 | Jeff Carter | Joe O'Brien Field | League Champions |
| 2000 | MIN | Gulf Coast Twins | GCL | Rk | team page | 56 | 33 | 23 | 5.0 | 345 | 236 | 109 | 2 | 4 | Al Newman | Hammond Stadium | dnq |
| 2000 | MON | Montreal Expos | MLB-NL | MLB | team page | 162 | 67 | 95 | 28.0 | 738 | 902 | -164 | 4 | 14 | Felipe Alou | Olympic Stadium | dnq |
| 2000 | MON | Ottawa Lynx | IL | AAA | team page | 141 | 53 | 88 | 31.0 | 599 | 795 | -196 | 6 | 13 | Jeff Cox, Rick Sweet | JetForm Park | dnq |
| 2000 | MON | Harrisburg Senators | East | AA | team page | 143 | 76 | 67 | 9.5 | 644 | 647 | -3 | 2 | 5 | Doug Sisson | Riverside Stadium | Lost in Semi-Finals |
| 2000 | MON | Jupiter Hammerheads | FSL | A+ | team page | 140 | 61 | 79 | -- | 669 | 722 | -53 | 0 | 11 | | Roger Dean Stadium | dnq |
| 2000 | MON | Cape Fear Crocs | SAL | A | team page | 138 | 64 | 74 | -- | 633 | 714 | -81 | 0 | 10 | Billy Masse | J.P. Riddle Stadium | dnq |
| 2000 | MON | Vermont Expos | NYPL | A- | team page | 75 | 45 | 30 | 1.0 | 407 | 325 | 82 | 3 | 4 | Tim Leiper | Centennial Field | dnq |
| 2000 | MON | Gulf Coast Expos | GCL | Rk | team page | 60 | 17 | 43 | 21.0 | 210 | 351 | -141 | 4 | 12 | Steve Phillips | McKechnie Field | dnq |
| 2000 | NYN | New York Mets | MLB-NL | MLB | team page | 162 | 94 | 68 | 1.0 | 807 | 738 | 69 | 2 | 4 | Bobby Valentine | Shea Stadium | Lost World Series (Yankees) |
| 2000 | NYN | Norfolk Tides | IL | AAA | team page | 144 | 65 | 79 | 16.5 | 654 | 647 | 7 | 3 | 11 | John Gibbons | Harbor Park | dnq |
| 2000 | NYN | Binghamton Mets | East | AA | team page | 140 | 82 | 58 | -- | 650 | 609 | 41 | 1 | 2 | Doug Davis | Binghamton Municipal Stadium | Lost in Semi-Finals |
| 2000 | NYN | St. Lucie Mets | FSL | A+ | team page | 139 | 81 | 58 | -- | 702 | 613 | 89 | 0 | 3 | Dave Engle | Thomas J. White Stadium | dnq |
| 2000 | NYN | Columbia Bombers | SAL | A | team page | 137 | 56 | 81 | -- | 533 | 682 | -149 | 0 | 13 | John Stephenson | Capital City Stadium | dnq |
| 2000 | NYN | Pittsfield Mets | NYPL | A- | team page | 75 | 38 | 37 | 8.0 | 336 | 324 | 12 | 5 | 7 | Tony Tijerina | Wahconah Park | dnq |
| 2000 | NYN | Kingsport Mets | App | Rk | team page | 67 | 35 | 32 | 12.5 | 334 | 305 | 29 | 3 | 4 | Edgar Alfonzo | Hunter Wright Stadium | dnq |
| 2000 | NYA | New York Yankees | MLB-AL | MLB | team page | 161 | 87 | 74 | -- | 871 | 814 | 57 | 1 | 5 | Joe Torre | Yankee Stadium I | Won World Series (Mets) |
| 2000 | NYA | Columbus Clippers | IL | AAA | team page | 144 | 75 | 69 | 6.0 | 729 | 720 | 9 | 2 | 8 | Trey Hillman | Cooper Stadium | dnq |
| 2000 | NYA | Norwich Navigators | East | AA | team page | 142 | 76 | 66 | 7.0 | 653 | 632 | 21 | 3 | 4 | Dan Radison | Senator Thomas J. Dodd Memorial Stadium | dnq |
| 2000 | NYA | Tampa Yankees | FSL | A+ | team page | 140 | 70 | 70 | -- | 551 | 548 | 3 | 0 | 7 | Tom Nieto | Legends Field | dnq |
| 2000 | NYA | Greensboro Bats | SAL | A | team page | 137 | 56 | 81 | -- | 630 | 697 | -67 | 0 | 12 | Stan Hough | World War Memorial Stadium | dnq |
| 2000 | NYA | Staten Island Yankees | NYPL | A- | team page | 74 | 46 | 28 | 0.5 | 375 | 258 | 117 | 2 | 2 | Joe Arnold | College of Staten Island Baseball Complex | League Champions |
| 2000 | NYA | Gulf Coast Yankees | GCL | Rk | team page | 60 | 38 | 22 | -- | 311 | 227 | 84 | 1 | 3 | Derek Shelton | Yankee Complex | Lost in Finals |
| 2000 | OAK | Oakland Athletics | MLB-AL | MLB | team page | 161 | 91 | 70 | -- | 947 | 813 | 134 | 1 | 2 | Art Howe | Network Associates Coliseum | Lost in 1st Round (Yankees) |
| 2000 | OAK | Sacramento River Cats | PCL | AAA | team page | 144 | 90 | 54 | -- | 864 | 681 | 183 | 1 | 2 | Bob Geren | Raley Field | Lost in Semi-Finals |
| 2000 | OAK | Midland RockHounds | Tex | AA | team page | 139 | 70 | 69 | 12.5 | 788 | 766 | 22 | 4 | 4 | Tony DeFrancesco | Christensen Stadium | dnq |
| 2000 | OAK | Modesto A's | Calif | A+ | team page | 140 | 76 | 64 | -- | 757 | 668 | 89 | 3 | 5 | Greg Sparks | John Thurman Field | Lost in Semi-Finals |
| 2000 | OAK | Visalia Oaks | Calif | A+ | team page | 140 | 78 | 62 | -- | 754 | 726 | 28 | 2 | 3 | Juan Navarette | Recreation Park | Lost in Finals |
| 2000 | OAK | Vancouver Canadians | Nwst | A- | team page | 76 | 39 | 37 | 1.0 | 344 | 322 | 22 | 2 | 4 | Dave Joppie | Nat Bailey Stadium | dnq |
| 2000 | OAK | Arizona Athletics | Ariz | Rk | team page | 54 | 29 | 25 | -- | 403 | 336 | 67 | 0 | 4 | John Kuehl | Papago Park Sports Facility | dnq |
| 2000 | PHI | Philadelphia Phillies | MLB-NL | MLB | team page | 162 | 65 | 97 | 30.0 | 692 | 830 | -138 | 5 | 15 | Terry Francona | Veterans Stadium | dnq |
| 2000 | PHI | Scranton/Wilkes-Barre Red Barons | IL | AAA | team page | 145 | 85 | 60 | 1.0 | 717 | 567 | 150 | 2 | 2 | Marc Bombard | Lackawanna County Stadium | Lost in Finals |
| 2000 | PHI | Reading Phillies | East | AA | team page | 142 | 85 | 57 | -- | 730 | 596 | 134 | 1 | 1 | Gary Varsho | GPU Stadium | Lost in Finals |
| 2000 | PHI | Clearwater Phillies | FSL | A+ | team page | 135 | 64 | 71 | -- | 562 | 594 | -32 | 0 | 9 | Ken Oberkfell | Jack Russell Memorial Stadium | dnq |
| 2000 | PHI | Piedmont Boll Weevils | SAL | A | team page | 137 | 90 | 47 | -- | 709 | 492 | 217 | 0 | 1 | Greg Legg | Fieldcrest Cannon Stadium | Lost in Semi-Finals |
| 2000 | PHI | Batavia Muckdogs | NYPL | A- | team page | 76 | 39 | 37 | 9.0 | 354 | 356 | -2 | 2 | 6 | Frank Klebe | Dwyer Stadium | Lost in Semi-Finals |
| 2000 | PHI | Gulf Coast Phillies | GCL | Rk | team page | 60 | 31 | 29 | 7.0 | 269 | 252 | 17 | 3 | 8 | Ramon Aviles | Carpenter Complex | dnq |
| 2000 | PIT | Pittsburgh Pirates | MLB-NL | MLB | team page | 162 | 69 | 93 | 26.0 | 793 | 888 | -95 | 5 | 13 | Gene Lamont | Three Rivers Stadium | dnq |
| 2000 | PIT | Nashville Sounds | PCL | AAA | team page | 142 | 63 | 79 | 19.0 | 681 | 758 | -77 | 4 | 13 | Richie Hebner, Trent Jewett | Herschel Greer Stadium | dnq |
| 2000 | PIT | Altoona Curve | East | AA | team page | 142 | 74 | 68 | 11.0 | 682 | 696 | -14 | 4 | 7 | Marty Brown | Blair County Ballpark | dnq |
| 2000 | PIT | Lynchburg Hillcats | Caro | A+ | team page | 138 | 66 | 72 | 0.5 | 594 | 668 | -74 | 2 | 6 | Tracy Woodson | Lynchburg City Stadium | Lost in Finals |
| 2000 | PIT | Hickory Crawdads | SAL | A | team page | 141 | 75 | 66 | -- | 762 | 709 | 53 | 0 | 5 | Jay Loviglio | L. P. Frans Stadium | dnq |
| 2000 | PIT | Williamsport Crosscutters | NYPL | A- | team page | 73 | 29 | 44 | 17.5 | 280 | 369 | -89 | 7 | 13 | Curtis Wilkerson | Bowman Field | dnq |
| 2000 | PIT | Gulf Coast Pirates | GCL | Rk | team page | 60 | 34 | 26 | 4.0 | 295 | 255 | 40 | 2 | 6 | Woody Huyke | Pirate City Stadium | dnq |
| 2000 | SDN | San Diego Padres | MLB-NL | MLB | team page | 162 | 76 | 86 | 21.0 | 752 | 815 | -63 | 5 | 10 | Bruce Bochy | Qualcomm Stadium | dnq |
| 2000 | SDN | Las Vegas Stars | PCL | AAA | team page | 143 | 73 | 70 | 16.5 | 830 | 754 | 76 | 2 | 7 | Duane Espy | Cashman Field | dnq |
| 2000 | SDN | Mobile BayBears | Sou | AA | team page | 139 | 66 | 73 | 14.5 | 591 | 635 | -44 | 4 | 8 | Mike Basso | Hank Aaron Stadium | dnq |
| 2000 | SDN | Rancho Cucamonga Quakes | Calif | A+ | team page | 140 | 61 | 79 | 28.0 | 703 | 808 | -105 | 4 | 8 | Tom LeVasseur | Rancho Cucamonga Epicenter | dnq |
| 2000 | SDN | Fort Wayne Wizards | Midw | A | team page | 137 | 72 | 65 | -- | 598 | 584 | 14 | 0 | 6 | Craig Colbert | Memorial Stadium | dnq |
| 2000 | SDN | Arizona Padres | Ariz | Rk | team page | 55 | 17 | 38 | -- | 252 | 383 | -131 | 0 | 8 | Howard Bushong | Peoria Sports Complex | dnq |
| 2000 | SDN | Idaho Falls Padres | Pio | Rk | team page | 74 | 45 | 29 | -- | 585 | 453 | 132 | 1 | 1 | Don Werner | McDermott Field | League Champions |
| 2000 | SFN | San Francisco Giants | MLB-NL | MLB | team page | 162 | 97 | 65 | -- | 925 | 747 | 178 | 1 | 1 | Dusty Baker | Pacific Bell Park | Lost in 1st Round (Mets) |
| 2000 | SFN | Fresno Grizzlies | PCL | AAA | team page | 141 | 57 | 84 | 31.5 | 692 | 887 | -195 | 4 | 15 | Shane Turner | Pete Beiden Field | dnq |
| 2000 | SFN | Shreveport Captains | Tex | AA | team page | 139 | 58 | 81 | 24.5 | 572 | 631 | -59 | 8 | 8 | Bill Hayes | Fair Grounds Field | Lost in Semi-Finals |
| 2000 | SFN | Bakersfield Blaze | Calif | A+ | team page | 140 | 80 | 60 | -- | 807 | 680 | 127 | 0 | 2 | Lenn Sakata | Sam Lynn Ballpark | Lost in 1st Round |
| 2000 | SFN | San Jose Giants | Calif | A+ | team page | 140 | 53 | 87 | -- | 656 | 855 | -199 | 5 | 9 | Keith Comstock | San Jose Municipal Stadium | dnq |
| 2000 | SFN | Salem-Keizer Volcanoes | Nwst | A- | team page | 76 | 36 | 40 | 4.0 | 361 | 386 | -25 | 3 | 7 | Fred Stanley | Volcanoes Stadium | dnq |
| 2000 | SFN | Arizona Giants | Ariz | Rk | team page | 54 | 22 | 32 | -- | 273 | 354 | -81 | 0 | 7 | Lemmie Miller | Scottsdale Stadium | dnq |
| 2000 | SEA | Seattle Mariners | MLB-AL | MLB | team page | 162 | 91 | 71 | 0.5 | 907 | 780 | 127 | 2 | 3 | Lou Piniella | Safeco Field | Lost ALCS (Yankees) |
| 2000 | SEA | Tacoma Rainiers | PCL | AAA | team page | 143 | 76 | 67 | 14.0 | 696 | 676 | 20 | 2 | 5 | Dave Myers | Cheney Stadium | dnq |
| 2000 | SEA | New Haven Ravens | East | AA | team page | 142 | 82 | 60 | 1.0 | 668 | 529 | 139 | 2 | 3 | Dan Rohn | Yale Field | League Champions |
| 2000 | SEA | Lancaster JetHawks | Calif | A+ | team page | 140 | 89 | 51 | -- | 933 | 721 | 212 | 1 | 1 | Mark Parent | Lancaster Municipal Stadium | Lost in Semi-Finals |
| 2000 | SEA | Wisconsin Timber Rattlers | Midw | A | team page | 138 | 78 | 60 | -- | 689 | 587 | 102 | 0 | 3 | Gary Thurman | Fox Cities Stadium | dnq |
| 2000 | SEA | Everett AquaSox | Nwst | A- | team page | 76 | 37 | 39 | 4.0 | 376 | 399 | -23 | 4 | 6 | Terry Pollreisz | Everett Memorial Stadium | dnq |
| 2000 | SEA | Arizona Mariners | Ariz | Rk | team page | 55 | 39 | 16 | -- | 408 | 276 | 132 | 0 | 1 | Omer Munoz | Peoria Sports Complex | League Champions |
| 2000 | SLN | St. Louis Cardinals | MLB-NL | MLB | team page | 162 | 95 | 67 | -- | 887 | 771 | 116 | 1 | 3 | Tony La Russa | Busch Stadium II | Lost NLCS (Mets) |
| 2000 | SLN | Memphis Redbirds | PCL | AAA | team page | 144 | 83 | 61 | -- | 771 | 659 | 112 | 1 | 4 | Gaylen Pitts | AutoZone Park | League Champions |
| 2000 | SLN | Arkansas Travelers | Tex | AA | team page | 139 | 68 | 71 | 14.5 | 696 | 723 | -27 | 5 | 5 | Chris Maloney | Ray Winder Field | dnq |
| 2000 | SLN | Potomac Cannons | Caro | A+ | team page | 138 | 62 | 76 | 4.5 | 597 | 642 | -45 | 4 | 8 | Joseph Cunningham | G. Richard Pfitzner Stadium | dnq |
| 2000 | SLN | Peoria Chiefs | Midw | A | team page | 137 | 63 | 74 | -- | 590 | 665 | -75 | 0 | 11 | Tom Lawless | Pete Vonachen Stadium at Meinen Field | dnq |
| 2000 | SLN | New Jersey Cardinals | NYPL | A- | team page | 76 | 31 | 45 | 15.5 | 264 | 414 | -150 | 6 | 12 | Jeff Shireman | Skylands Park | dnq |
| 2000 | SLN | Johnson City Cardinals | App | Rk | team page | 68 | 24 | 44 | 24.0 | 335 | 409 | -74 | 5 | 9 | Luis Melendez | Howard Johnson Field | dnq |
| 2000 | TBA | Tampa Bay Devil Rays | MLB-AL | MLB | team page | 161 | 69 | 92 | 18.0 | 733 | 842 | -109 | 5 | 13 | Larry Rothschild | Tropicana Field | dnq |
| 2000 | TBA | Durham Bulls | IL | AAA | team page | 143 | 81 | 62 | -- | 746 | 719 | 27 | 1 | 4 | Billy Evers | Durham Bulls Athletic Park | Lost in Semi-Finals |
| 2000 | TBA | Orlando Rays | Sou | AA | team page | 136 | 65 | 71 | 4.0 | 512 | 549 | -37 | 4 | 7 | Mike Ramsey | Champion Stadium | dnq |
| 2000 | TBA | St. Petersburg Devil Rays | FSL | A+ | team page | 139 | 58 | 81 | -- | 549 | 676 | -127 | 0 | 13 | Julio Garcia | Progress Energy Park | dnq |
| 2000 | TBA | Charleston (sc) RiverDogs | SAL | A | team page | 139 | 73 | 66 | -- | 670 | 648 | 22 | 0 | 6 | Charlie Montoyo | Joseph P. Riley, Jr. Park | dnq |
| 2000 | TBA | Hudson Valley Renegades | NYPL | A- | team page | 75 | 23 | 52 | 23.0 | 298 | 411 | -113 | 7 | 14 | Dave Silvestri | Dutchess Stadium | dnq |
| 2000 | TBA | Princeton Devil Rays | App | Rk | team page | 68 | 34 | 34 | 4.0 | 292 | 327 | -35 | 2 | 6 | Edwin Rodriguez | H.P. Hunnicut Field | dnq |
| 2000 | TEX | Texas Rangers | MLB-AL | MLB | team page | 162 | 71 | 91 | 20.5 | 848 | 974 | -126 | 4 | 12 | Johnny Oates | The Ballpark in Arlington | dnq |
| 2000 | TEX | Oklahoma RedHawks | PCL | AAA | team page | 143 | 69 | 74 | 13.5 | 735 | 756 | -21 | 2 | 8 | DeMarlo Hale | AT&T Bricktown Ballpark | dnq |
| 2000 | TEX | Tulsa Drillers | Tex | AA | team page | 140 | 64 | 76 | 19.0 | 806 | 804 | 2 | 7 | 6 | Bob Jones, Jim Byrd | Drillers Stadium | dnq |
| 2000 | TEX | Charlotte Rangers | FSL | A+ | team page | 139 | 78 | 61 | -- | 748 | 639 | 109 | 0 | 4 | Jim Byrd | Charlotte County Stadium | dnq |
| 2000 | TEX | Savannah Sand Gnats | SAL | A | team page | 139 | 74 | 65 | -- | 585 | 551 | 34 | 0 | 4 | Paul Carey | Grayson Stadium | dnq |
| 2000 | TEX | Gulf Coast Rangers | GCL | Rk | team page | 56 | 38 | 18 | -- | 318 | 253 | 65 | 1 | 1 | Darryl Kennedy | Charlotte County Stadium | League Champions |
| 2000 | TEX | Pulaski Rangers | App | Rk | team page | 68 | 40 | 28 | 8.0 | 412 | 276 | 136 | 2 | 2 | Bruce Crabbe | Calfee Park | dnq |
| 2000 | TOR | Toronto Blue Jays | MLB-AL | MLB | team page | 162 | 83 | 79 | 4.5 | 861 | 908 | -47 | 3 | 7 | Jim Fregosi | SkyDome | dnq |
| 2000 | TOR | Syracuse SkyChiefs | IL | AAA | team page | 140 | 74 | 66 | 9.5 | 632 | 583 | 49 | 4 | 7 | Pat Kelly, Omar Malave, Mel Queen | P&C Stadium | dnq |
| 2000 | TOR | Tennessee Smokies | Sou | AA | team page | 140 | 71 | 69 | -- | 640 | 651 | -11 | 1 | 4 | Rocket Wheeler | Smokies Stadium | dnq |
| 2000 | TOR | Dunedin Blue Jays | FSL | A+ | team page | 138 | 84 | 54 | -- | 760 | 595 | 165 | 0 | 1 | Marty Pevey | Dunedin Stadium | dnq |
| 2000 | TOR | Hagerstown Suns | SAL | A | team page | 137 | 63 | 74 | -- | 621 | 681 | -60 | 0 | 11 | Rolando Pino | Municipal Stadium | dnq |
| 2000 | TOR | Queens Kings | NYPL | A- | team page | 75 | 46 | 29 | -- | 364 | 304 | 60 | 1 | 3 | Eduardo Rodriguez | Jack Kaiser Stadium | Lost in Semi-Finals |
| 2000 | TOR | Medicine Hat Blue Jays | Pio | Rk | team page | 76 | 36 | 40 | 8.0 | 457 | 443 | 14 | 3 | 6 | Paul Elliott | Athletic Park | Lost in Semi-Finals |