| 1980 | ATL | Atlanta Braves | MLB-NL | MLB | team page | 161 | 81 | 80 | 11.0 | 630 | 660 | -30 | 4 | 7 | Bobby Cox | Atlanta-Fulton County Stadium | dnq |
| 1980 | ATL | Richmond Braves | IL | AAA | team page | 140 | 69 | 71 | 14.0 | 550 | 557 | -7 | 4 | 4 | Fred Hatfield | Parker Field | Lost in Semi-Finals |
| 1980 | ATL | Savannah Braves | Sou | AA | team page | 144 | 77 | 67 | -- | 553 | 565 | -12 | 1 | 3 | Eddie Haas | Grayson Stadium | Lost in Semi-Finals |
| 1980 | ATL | Durham Bulls | Caro | A+ | team page | 140 | 84 | 56 | -- | 744 | 635 | 109 | 1 | 2 | Al Gallagher | Durham Athletic Park | Lost in Finals |
| 1980 | ATL | Anderson Braves | SAL | A | team page | 140 | 64 | 76 | 14.5 | 751 | 693 | 58 | 3 | 6 | Sonny Jackson | Anderson Memorial Stadium | dnq |
| 1980 | ATL | Gulf Coast Braves | GCL | Rk | team page | 62 | 37 | 25 | 2.5 | 261 | 254 | 7 | 3 | 3 | Pedro Gonzalez | West Palm Beach Municipal Stadium | dnq |
| 1980 | BAL | Baltimore Orioles | MLB-AL | MLB | team page | 162 | 100 | 62 | 3.0 | 805 | 640 | 165 | 2 | 2 | Earl Weaver | Memorial Stadium | dnq |
| 1980 | BAL | Rochester Red Wings | IL | AAA | team page | 139 | 74 | 65 | 8.5 | 592 | 579 | 13 | 3 | 3 | Doc Edwards | Silver Stadium | Lost in Semi-Finals |
| 1980 | BAL | Charlotte O's | Sou | AA | team page | 144 | 72 | 72 | 5.0 | 602 | 604 | -2 | 3 | 5 | Jimmy Williams | Crockett Park | League Champions |
| 1980 | BAL | Miami Orioles | FSL | A+ | team page | 136 | 51 | 85 | 31.5 | 520 | 621 | -101 | 5 | 10 | | Miami Stadium | dnq |
| 1980 | BAL | Bluefield Orioles | App | Rk | team page | 68 | 29 | 39 | 16.0 | 361 | 373 | -12 | 5 | 5 | Grady Little | Bowen Field at Peters Park | dnq |
| 1980 | BOS | Boston Red Sox | MLB-AL | MLB | team page | 160 | 83 | 77 | 19.0 | 757 | 767 | -10 | 4 | 5 | Don Zimmer, Johnny Pesky | Fenway Park | dnq |
| 1980 | BOS | Pawtucket Red Sox | IL | AAA | team page | 139 | 62 | 77 | 20.5 | 523 | 566 | -43 | 7 | 7 | Joe Morgan | McCoy Stadium | dnq |
| 1980 | BOS | Bristol Red Sox | East | AA | team page | 139 | 79 | 60 | -- | 607 | 596 | 11 | 1 | 1 | Tony Torchia | Muzzy Field | dnq |
| 1980 | BOS | Winston-Salem Red Sox | Caro | A+ | team page | 140 | 76 | 64 | 8.0 | 706 | 599 | 107 | 2 | 4 | Buddy Hunter | Ernie Shore Field | dnq |
| 1980 | BOS | Winter Haven Red Sox | FSL | A+ | team page | 140 | 60 | 80 | 27.5 | 518 | 653 | -135 | 4 | 8 | Rac Slider | Chain of Lakes Park | dnq |
| 1980 | BOS | Elmira Pioneers | NYPL | A- | team page | 74 | 39 | 35 | 10.0 | 398 | 371 | 27 | 3 | 4 | Dick Berardino | Dunn Field | dnq |
| 1980 | CAL | California Angels | MLB-AL | MLB | team page | 160 | 65 | 95 | 31.0 | 698 | 797 | -99 | 6 | 13 | Jim Fregosi | Anaheim Stadium | dnq |
| 1980 | CAL | Salt Lake Gulls | PCL | AAA | team page | 142 | 77 | 65 | 8.0 | 718 | 728 | -10 | 3 | 4 | Moose Stubing | Derks Field | dnq |
| 1980 | CAL | El Paso Diablos | Tex | AA | team page | 136 | 50 | 86 | 27.0 | 740 | 873 | -133 | 4 | 7 | Jim Saul | Dudley Field | dnq |
| 1980 | CAL | Salinas Angels | Calif | A+ | team page | 140 | 61 | 79 | 13.0 | 504 | 708 | -204 | 4 | 7 | Tommy Zimmer | Salinas Municipal Stadium | dnq |
| 1980 | CAL | Idaho Falls Angels | Pio | Rk | team page | 70 | 34 | 36 | 10.0 | 382 | 440 | -58 | 2 | 4 | Reuben Rodriguez | McDermott Field | dnq |
| 1980 | CHN | Chicago Cubs | MLB-NL | MLB | team page | 162 | 64 | 98 | 27.0 | 614 | 728 | -114 | 6 | 12 | Preston Gomez, Joey Amalfitano | Wrigley Field | dnq |
| 1980 | CHN | Wichita Aeros | Amer | AAA | team page | 135 | 61 | 74 | 30.5 | 638 | 675 | -37 | 4 | 6 | Jack Hiatt | Lawrence-Dumont Stadium | dnq |
| 1980 | CHN | Midland Cubs | Tex | AA | team page | 136 | 64 | 72 | 13.0 | 814 | 824 | -10 | 3 | 6 | George Enright, Randy Hundley, Les Moss | Cubs Stadium | dnq |
| 1980 | CHN | Quad Cities Cubs | Midw | A | team page | 139 | 74 | 65 | -- | 657 | 546 | 111 | 1 | 4 | Jim Napier | John O'Donnell Stadium | Lost in Finals |
| 1980 | CHN | Geneva Cubs | NYPL | A- | team page | 74 | 48 | 26 | -- | 408 | 270 | 138 | 1 | 2 | Bob Hartsfield | McDonough Park | Lost in Semi-Finals |
| 1980 | CHN | Gulf Coast Cubs | GCL | Rk | team page | 62 | 33 | 29 | 6.5 | 288 | 302 | -14 | 6 | 6 | Rich Morales | Sarasota | dnq |
| 1980 | CHA | Chicago White Sox | MLB-AL | MLB | team page | 160 | 70 | 90 | 26.0 | 587 | 722 | -135 | 5 | 11 | Tony La Russa | Comiskey Park | dnq |
| 1980 | CHA | Iowa Oaks | Amer | AAA | team page | 136 | 59 | 77 | 16.0 | 583 | 687 | -104 | 3 | 7 | Sam Ewing | Sec Taylor Stadium | dnq |
| 1980 | CHA | Glens Falls White Sox | East | AA | team page | 137 | 63 | 74 | 14.0 | 738 | 770 | -32 | 4 | 7 | Mike Pazik | East Field Stadium | dnq |
| 1980 | CHA | Appleton Foxes | Midw | A | team page | 139 | 76 | 63 | 9.0 | 691 | 580 | 111 | 3 | 2 | Gordy Lund | Goodland Field | dnq |
| 1980 | CHA | Gulf Coast White Sox | GCL | Rk | team page | 63 | 22 | 41 | 18.0 | 277 | 356 | -79 | 9 | 10 | Duane Shaffer | Payne Park | dnq |
| 1980 | CIN | Cincinnati Reds | MLB-NL | MLB | team page | 162 | 89 | 73 | 3.5 | 707 | 670 | 37 | 3 | 5 | John McNamara | Riverfront Stadium | dnq |
| 1980 | CIN | Indianapolis Indians | Amer | AAA | team page | 135 | 58 | 77 | 16.5 | 506 | 624 | -118 | 4 | 8 | Jim Beauchamp | Bush Stadium | dnq |
| 1980 | CIN | Waterbury Reds | East | AA | team page | 139 | 75 | 64 | 4.0 | 515 | 484 | 31 | 3 | 4 | Mike Compton | Municipal Stadium | Lost in Finals |
| 1980 | CIN | Tampa Tarpons | FSL | A+ | team page | 131 | 64 | 67 | 19.0 | 432 | 444 | -12 | 3 | 5 | | Al Lopez Field | dnq |
| 1980 | CIN | Cedar Rapids Reds | Midw | A | team page | 140 | 59 | 81 | 15.5 | 516 | 639 | -123 | 4 | 7 | Jim Lett | Veterans Field | dnq |
| 1980 | CIN | Eugene Emeralds | Nwst | A- | team page | 70 | 37 | 33 | -- | 448 | 410 | 38 | 1 | 3 | Greg Riddoch | Civic Stadium | Co-League Champions |
| 1980 | CIN | Billings Mustangs | Pio | Rk | team page | 70 | 44 | 26 | -- | 455 | 344 | 111 | 1 | 3 | Jim Hoff | Cobb Field | Lost in Finals |
| 1980 | CLE | Cleveland Indians | MLB-AL | MLB | team page | 160 | 79 | 81 | 23.0 | 738 | 807 | -69 | 6 | 8 | Dave Garcia | Cleveland Stadium | dnq |
| 1980 | CLE | Tacoma Tigers | PCL | AAA | team page | 148 | 74 | 74 | 9.5 | 740 | 724 | 16 | 3 | 6 | Gene Dusan | Cheney Stadium | dnq |
| 1980 | CLE | Chattanooga Lookouts | Sou | AA | team page | 144 | 61 | 83 | 36.5 | 679 | 710 | -31 | 5 | 9 | Woody Smith | Engel Stadium | dnq |
| 1980 | CLE | Waterloo Indians | Midw | A | team page | 141 | 86 | 55 | -- | 799 | 641 | 158 | 1 | 1 | Cal Emery | Municipal Stadium | League Champions |
| 1980 | CLE | Batavia Trojans | NYPL | A- | team page | 73 | 31 | 42 | 16.5 | 363 | 416 | -53 | 2 | 5 | Rick Colzie | Dwyer Stadium | dnq |
| 1980 | DET | Detroit Tigers | MLB-AL | MLB | team page | 162 | 84 | 78 | 19.0 | 830 | 757 | 73 | 5 | 6 | Sparky Anderson | Tiger Stadium | dnq |
| 1980 | DET | Evansville Triplets | Amer | AAA | team page | 135 | 61 | 74 | 13.5 | 575 | 656 | -81 | 2 | 5 | Jim Leyland | Bosse Field | dnq |
| 1980 | DET | Montgomery Rebels | Sou | AA | team page | 144 | 68 | 76 | 29.5 | 576 | 639 | -63 | 3 | 6 | Roy Majtyka | Paterson Field | dnq |
| 1980 | DET | Lakeland Tigers | FSL | A+ | team page | 133 | 56 | 77 | 28.0 | 591 | 633 | -42 | 5 | 9 | | Joker Marchant Stadium | dnq |
| 1980 | DET | Bristol Tigers | App | Rk | team page | 69 | 36 | 33 | 9.5 | 312 | 352 | -40 | 2 | 2 | Tom Kotchman | Devault Memorial Stadium | dnq |
| 1980 | HOU | Houston Astros | MLB-NL | MLB | team page | 163 | 93 | 70 | -- | 637 | 589 | 48 | 1 | 1 | Bill Virdon | Astrodome | Lost NLCS (Phillies) |
| 1980 | HOU | Tucson Toros | PCL | AAA | team page | 146 | 87 | 59 | -- | 793 | 722 | 71 | 1 | 1 | Jimmy Johnson | Hi Corbett Field | Lost in Semi-Finals |
| 1980 | HOU | Columbus Astros | Sou | AA | team page | 144 | 76 | 68 | 1.0 | 660 | 600 | 60 | 2 | 4 | Matt Galante | Golden Park | dnq |
| 1980 | HOU | Daytona Astros | FSL | A+ | team page | 137 | 86 | 51 | -- | 684 | 485 | 199 | 1 | 1 | Carlos Alfonso | Jackie Robinson Ballpark | dnq |
| 1980 | HOU | Gulf Coast Astros Blue | GCL | Rk | team page | 62 | 38 | 24 | 1.5 | 305 | 242 | 63 | 2 | 2 | Eric Swanson | Saraosta | dnq |
| 1980 | HOU | Gulf Coast Astros Orange | GCL | Rk | team page | 62 | 34 | 28 | 5.5 | 296 | 251 | 45 | 5 | 5 | Fernando Tatis | Saraosta | dnq |
| 1980 | KCA | Kansas City Royals | MLB-AL | MLB | team page | 162 | 97 | 65 | -- | 809 | 694 | 115 | 1 | 3 | Jim Frey | Royals Stadium | Lost World Series (Phillies) |
| 1980 | KCA | Omaha Royals | Amer | AAA | team page | 136 | 66 | 70 | 26.0 | 637 | 677 | -40 | 3 | 4 | Joe Sparks | Johnny Rosenblatt Stadium | dnq |
| 1980 | KCA | Jacksonville Suns | Sou | AA | team page | 144 | 63 | 81 | 34.5 | 664 | 740 | -76 | 4 | 8 | Gene Lamont | Sam W. Wolfson Baseball Park | dnq |
| 1980 | KCA | Fort Myers Royals | FSL | A+ | team page | 136 | 66 | 70 | 16.5 | 645 | 596 | 49 | 3 | 6 | | Terry Park Ballfield | dnq |
| 1980 | KCA | Charleston (sc) Royals | SAL | A | team page | 139 | 78 | 61 | -- | 708 | 707 | 1 | 1 | 2 | Ron Mihal | College Park | Lost in Finals |
| 1980 | KCA | Gulf Coast Royals Blue | GCL | Rk | team page | 63 | 40 | 23 | -- | 349 | 247 | 102 | 1 | 1 | Joe Jones | Baseball City Stadium | League Champions |
| 1980 | KCA | Gulf Coast Royals Gold | GCL | Rk | team page | 62 | 22 | 40 | 17.5 | 241 | 301 | -60 | 10 | 9 | Roy Tanner | Baseball City Stadium | dnq |
| 1980 | LAN | Los Angeles Dodgers | MLB-NL | MLB | team page | 163 | 92 | 71 | 1.0 | 663 | 591 | 72 | 2 | 2 | Tommy Lasorda | Dodger Stadium | dnq |
| 1980 | LAN | Albuquerque Dukes | PCL | AAA | team page | 147 | 85 | 62 | 2.5 | 785 | 696 | 89 | 2 | 2 | Del Crandall | Albuquerque Sports Stadium | League Champions |
| 1980 | LAN | San Antonio Dodgers | Tex | AA | team page | 136 | 74 | 62 | 3.0 | 705 | 586 | 119 | 2 | 4 | Don LeJohn | V.J. Keefe Memorial Stadium | Lost in Finals |
| 1980 | LAN | Lodi Dodgers | Calif | A+ | team page | 140 | 57 | 83 | 32.5 | 695 | 878 | -183 | 4 | 8 | Stan Wasiak | Lawrence Park | dnq |
| 1980 | LAN | Vero Beach Dodgers | FSL | A+ | team page | 141 | 82 | 59 | 3.0 | 667 | 589 | 78 | 2 | 3 | Stan Wasiak | Holman Stadium | dnq |
| 1980 | LAN | Lethbridge Dodgers | Pio | Rk | team page | 70 | 52 | 18 | -- | 537 | 315 | 222 | 1 | 1 | Gail Henley | Henderson Stadium | League Champions |
| 1980 | MIL | Milwaukee Brewers | MLB-AL | MLB | team page | 162 | 86 | 76 | 17.0 | 811 | 682 | 129 | 3 | 4 | George Bamberger, Buck Rodgers | County Stadium | dnq |
| 1980 | MIL | Vancouver Canadians | PCL | AAA | team page | 139 | 79 | 60 | -- | 620 | 539 | 81 | 1 | 3 | Bob Didier | Nat Bailey Stadium | Lost in Semi-Finals |
| 1980 | MIL | Holyoke Millers | East | AA | team page | 139 | 78 | 61 | -- | 586 | 527 | 59 | 1 | 2 | Jim Saul | Mackenzie Stadium | League Champions |
| 1980 | MIL | Stockton Ports | Calif | A+ | team page | 141 | 90 | 51 | -- | 704 | 551 | 153 | 1 | 1 | Tony Muser | Billy Hebert Field | League Champions |
| 1980 | MIL | Burlington Bees | Midw | A | team page | 142 | 70 | 72 | 5.5 | 620 | 669 | -49 | 2 | 5 | Duane Espy | Community Field | Lost in Semi-Finals |
| 1980 | MIL | Butte Copper Kings | Pio | Rk | team page | 69 | 29 | 40 | 14.5 | 498 | 507 | -9 | 4 | 6 | Ken Richardson | Alumni Coliseum | dnq |
| 1980 | MIN | Minnesota Twins | MLB-AL | MLB | team page | 161 | 77 | 84 | 19.5 | 670 | 724 | -54 | 3 | 9 | Gene Mauch, Johnny Goryl | Metropolitan Stadium | dnq |
| 1980 | MIN | Toledo Mud Hens | IL | AAA | team page | 140 | 77 | 63 | 6.0 | 631 | 542 | 89 | 2 | 2 | Cal Ermer | Lucas County Stadium | Lost in Finals |
| 1980 | MIN | Orlando Twins | Sou | AA | team page | 143 | 65 | 78 | 11.5 | 603 | 687 | -84 | 4 | 7 | Roy McMillan | Tinker Field | dnq |
| 1980 | MIN | Visalia Oaks | Calif | A+ | team page | 140 | 71 | 69 | 3.0 | 628 | 689 | -61 | 3 | 6 | Tom Kelly | Recreation Park | Lost in Finals |
| 1980 | MIN | Wisconsin Rapids Twins | Midw | A | team page | 141 | 77 | 64 | 9.0 | 701 | 598 | 103 | 2 | 3 | Rick Stelmaszek | Witter Field | Lost in Semi-Finals |
| 1980 | MIN | Elizabethton Twins | App | Rk | team page | 68 | 32 | 36 | 13.0 | 378 | 370 | 8 | 4 | 4 | Fred Waters | Joe O'Brien Field | dnq |
| 1980 | MON | Montreal Expos | MLB-NL | MLB | team page | 162 | 90 | 72 | 1.0 | 694 | 629 | 65 | 2 | 4 | Dick Williams | Olympic Stadium | dnq |
| 1980 | MON | Denver Bears | Amer | AAA | team page | 136 | 92 | 44 | -- | 842 | 575 | 267 | 1 | 1 | Billy Gardner | Mile High Stadium | Lost in Finals |
| 1980 | MON | Memphis Chicks | Sou | AA | team page | 144 | 83 | 61 | 14.5 | 768 | 598 | 170 | 2 | 2 | Larry Bearnarth | Tim McCarver Stadium | Lost in Finals |
| 1980 | MON | West Palm Beach Expos | FSL | A+ | team page | 137 | 64 | 73 | 19.0 | 627 | 633 | -6 | 4 | 7 | | West Palm Beach Municipal Stadium | dnq |
| 1980 | MON | Jamestown Expos | NYPL | A- | team page | 71 | 29 | 42 | 17.5 | 321 | 359 | -38 | 4 | 6 | Pat Daugherty | College Stadium | dnq |
| 1980 | MON | Calgary Expos | Pio | Rk | team page | 69 | 23 | 46 | 28.5 | 341 | 422 | -81 | 3 | 7 | Steve Boros | Burns Stadium | dnq |
| 1980 | NYN | New York Mets | MLB-NL | MLB | team page | 162 | 67 | 95 | 24.0 | 611 | 702 | -91 | 5 | 11 | Joe Torre | Shea Stadium | dnq |
| 1980 | NYN | Tidewater Tides | IL | AAA | team page | 139 | 67 | 72 | 15.5 | 512 | 516 | -4 | 6 | 6 | Frank Verdi | Met Park | dnq |
| 1980 | NYN | Jackson Mets | Tex | AA | team page | 136 | 74 | 62 | 7.0 | 601 | 487 | 114 | 3 | 5 | Bob Wellman | Smith-Wills Stadium | Lost in Semi-Finals |
| 1980 | NYN | Lynchburg Mets | Caro | A+ | team page | 139 | 71 | 68 | 28.5 | 634 | 622 | 12 | 3 | 5 | Jack Aker | Lynchburg City Stadium | dnq |
| 1980 | NYN | Grays Harbor Loggers | Nwst | A- | team page | 69 | 33 | 36 | 11.5 | 388 | 377 | 11 | 4 | 6 | Bill Bryk | Olympic Stadium | dnq |
| 1980 | NYN | Little Falls Mets | NYPL | A- | team page | 73 | 40 | 33 | 8.5 | 389 | 368 | 21 | 2 | 3 | Dan Monzon | Little Falls Veterans Memorial Park | dnq |
| 1980 | NYN | Kingsport Mets | App | Rk | team page | 70 | 35 | 35 | 11.0 | 356 | 370 | -14 | 3 | 3 | Chuck Hiller | Dobyns-Bennett | dnq |
| 1980 | NYA | New York Yankees | MLB-AL | MLB | team page | 162 | 103 | 59 | -- | 820 | 662 | 158 | 1 | 1 | Dick Howser | Yankee Stadium I | Lost ALCS (Royals) |
| 1980 | NYA | Columbus Clippers | IL | AAA | team page | 140 | 83 | 57 | -- | 590 | 477 | 113 | 1 | 1 | Joe Altobelli | Cooper Stadium | League Champions |
| 1980 | NYA | Nashville Sounds | Sou | AA | team page | 143 | 97 | 46 | -- | 753 | 550 | 203 | 1 | 1 | Stump Merrill | Herschel Greer Stadium | Lost in Semi-Finals |
| 1980 | NYA | Fort Lauderdale Yankees | FSL | A+ | team page | 137 | 83 | 54 | -- | 552 | 490 | 62 | 1 | 2 | | Fort Lauderdale Stadium | dnq |
| 1980 | NYA | Greensboro Hornets | SAL | A | team page | 139 | 82 | 57 | -- | 765 | 626 | 139 | 1 | 1 | Bob Schaefer | World War Memorial Stadium | League Champions |
| 1980 | NYA | Oneonta Yankees | NYPL | A- | team page | 74 | 49 | 25 | -- | 366 | 263 | 103 | 1 | 1 | Art Mazmanian | Damaschke Field | Lost in Finals |
| 1980 | NYA | Gulf Coast Yankees | GCL | Rk | team page | 62 | 27 | 35 | 12.5 | 248 | 289 | -41 | 7 | 7 | Carlos Tosca | Yankee Complex | dnq |
| 1980 | NYA | Paintsville Yankees | App | Rk | team page | 70 | 46 | 24 | -- | 459 | 313 | 146 | 1 | 1 | Mike Easom | Paul G. Fyffe Field | dnq |
| 1980 | OAK | Oakland Athletics | MLB-AL | MLB | team page | 162 | 83 | 79 | 14.0 | 686 | 642 | 44 | 2 | 7 | Billy Martin | Oakland-Alameda County Coliseum | dnq |
| 1980 | OAK | Ogden A's | PCL | AAA | team page | 142 | 59 | 83 | 26.0 | 759 | 855 | -96 | 4 | 9 | Jose Pagan | John Affleck park | dnq |
| 1980 | OAK | West Haven Whitecaps | East | AA | team page | 139 | 47 | 92 | 32.0 | 512 | 731 | -219 | 4 | 8 | Edward Nottle | Quigley Stadium | dnq |
| 1980 | OAK | Modesto A's | Calif | A+ | team page | 139 | 74 | 65 | 15.0 | 729 | 641 | 88 | 3 | 2 | Keith Lieppman | Del Webb Field | dnq |
| 1980 | OAK | Medford A's | Nwst | A- | team page | 70 | 22 | 48 | 15.0 | 377 | 518 | -141 | 4 | 8 | Bradley Fischer | Miles Field | dnq |
| 1980 | PHI | Philadelphia Phillies | MLB-NL | MLB | team page | 162 | 91 | 71 | -- | 728 | 639 | 89 | 1 | 3 | Dallas Green | Veterans Stadium | Won World Series (Royals) |
| 1980 | PHI | Oklahoma City 89ers | Amer | AAA | team page | 135 | 70 | 65 | 21.5 | 697 | 684 | 13 | 2 | 3 | Jim Snyder | All Sports Stadium | dnq |
| 1980 | PHI | Reading Phillies | East | AA | team page | 139 | 78 | 61 | 1.0 | 780 | 615 | 165 | 2 | 3 | Ron Clark | Reading Municipal Memorial Stadium | Lost in Semi-Finals |
| 1980 | PHI | Peninsula Pilots | Caro | A+ | team page | 140 | 100 | 40 | -- | 783 | 469 | 314 | 1 | 1 | Bill Dancy | War Memorial Stadium | League Champions |
| 1980 | PHI | Spartanburg Phillies | SAL | A | team page | 138 | 73 | 65 | 4.5 | 653 | 641 | 12 | 2 | 3 | Tom Harmon | Duncan Park | Lost in Semi-Finals |
| 1980 | PHI | Central Oregon Phillies | Nwst | A- | team page | 70 | 31 | 39 | 6.0 | 418 | 436 | -18 | 3 | 7 | P.J. Carey | Vince Genna Stadium | dnq |
| 1980 | PHI | Helena Phillies | Pio | Rk | team page | 70 | 32 | 38 | 12.0 | 335 | 413 | -78 | 3 | 5 | Roly De Armas | Kindrick Field | dnq |
| 1980 | PIT | Pittsburgh Pirates | MLB-NL | MLB | team page | 162 | 83 | 79 | 8.0 | 666 | 646 | 20 | 3 | 6 | Chuck Tanner | Three Rivers Stadium | dnq |
| 1980 | PIT | Portland Beavers | PCL | AAA | team page | 145 | 69 | 76 | 13.0 | 683 | 611 | 72 | 4 | 7 | Jim Mahoney | Civic Stadium | dnq |
| 1980 | PIT | Buffalo Bisons | East | AA | team page | 137 | 67 | 70 | 10.0 | 745 | 674 | 71 | 2 | 5 | Steve Demeter | War Memorial Stadium | Lost in Semi-Finals |
| 1980 | PIT | Salem Pirates | Caro | A+ | team page | 139 | 79 | 60 | 20.5 | 686 | 614 | 72 | 2 | 3 | Johnny Lipon | Salem Municipal Stadium | dnq |
| 1980 | PIT | Shelby Pirates | SAL | A | team page | 138 | 58 | 80 | 23.5 | 617 | 762 | -145 | 4 | 8 | Joe Frisina | Veterans Field | dnq |
| 1980 | PIT | Gulf Coast Pirates | GCL | Rk | team page | 63 | 24 | 39 | 16.0 | 245 | 332 | -87 | 8 | 8 | Woody Huyke | Pirate City Stadium | dnq |
| 1980 | SDN | San Diego Padres | MLB-NL | MLB | team page | 162 | 73 | 89 | 19.5 | 591 | 654 | -63 | 6 | 10 | Jerry Coleman | Jack Murphy Stadium | dnq |
| 1980 | SDN | Hawaii Islanders | PCL | AAA | team page | 141 | 76 | 65 | 4.0 | 620 | 561 | 59 | 2 | 5 | Doug Rader | Aloha Stadium | Lost in Finals |
| 1980 | SDN | Amarillo Gold Sox | Tex | AA | team page | 136 | 77 | 59 | -- | 686 | 692 | -6 | 1 | 2 | Eddie Watt | Potter County Memorial Stadium | Lost in Semi-Finals |
| 1980 | SDN | Reno Silver Sox | Calif | A+ | team page | 141 | 75 | 66 | 15.0 | 804 | 728 | 76 | 2 | 3 | Jack Maloof | Moana Stadium | dnq |
| 1980 | SDN | Walla Walla Padres | Nwst | A- | team page | 69 | 35 | 34 | 9.5 | 407 | 435 | -28 | 3 | 4 | Curt Daniels | Borleske Stadium | dnq |
| 1980 | SFN | San Francisco Giants | MLB-NL | MLB | team page | 161 | 75 | 86 | 17.0 | 573 | 634 | -61 | 5 | 8 | Dave Bristol | Candlestick Park | dnq |
| 1980 | SFN | Phoenix Giants | PCL | AAA | team page | 148 | 53 | 95 | 35.0 | 722 | 869 | -147 | 5 | 10 | Rocky Bridges | Phoenix Municipal Stadium | dnq |
| 1980 | SFN | Shreveport Captains | Tex | AA | team page | 136 | 49 | 87 | 32.0 | 452 | 587 | -135 | 4 | 8 | Andy Gilbert | SPAR Stadium | dnq |
| 1980 | SFN | Fresno Giants | Calif | A+ | team page | 140 | 74 | 66 | -- | 664 | 581 | 83 | 1 | 4 | Jack Mull | Euless Ballpark | Lost in Semi-Finals |
| 1980 | SFN | Clinton Giants | Midw | A | team page | 141 | 62 | 79 | 13.0 | 548 | 678 | -130 | 3 | 6 | Wayne Cato | Riverview Stadium | dnq |
| 1980 | SFN | Great Falls Giants | Pio | Rk | team page | 70 | 49 | 21 | 3.0 | 510 | 354 | 156 | 2 | 2 | Ernie Rodriguez | Legion Field | dnq |
| 1980 | SEA | Seattle Mariners | MLB-AL | MLB | team page | 162 | 59 | 103 | 38.0 | 610 | 793 | -183 | 7 | 14 | Darrell Johnson, Maury Wills | The Kingdome | dnq |
| 1980 | SEA | Spokane Indians | PCL | AAA | team page | 140 | 60 | 80 | 19.5 | 588 | 691 | -103 | 5 | 8 | Rene Lachemann | Avista Stadium | dnq |
| 1980 | SEA | Lynn Sailors | East | AA | team page | 137 | 66 | 71 | 11.0 | 601 | 685 | -84 | 3 | 6 | Bobby Floyd | Fraser Field | dnq |
| 1980 | SEA | San Jose Missions | Calif | A+ | team page | 139 | 73 | 66 | 0.5 | 746 | 631 | 115 | 2 | 5 | Bill Plummer | San Jose Municipal Stadium | dnq |
| 1980 | SEA | Bellingham Mariners | Nwst | A- | team page | 70 | 45 | 25 | -- | 451 | 335 | 116 | 1 | 1 | Jeff Scott | Joe Martin Field | Co-League Champions |
| 1980 | SLN | St. Louis Cardinals | MLB-NL | MLB | team page | 162 | 74 | 88 | 17.0 | 738 | 710 | 28 | 4 | 9 | Whitey Herzog, Ken Boyer, Red Schoendienst, Busch Stadium II | dnq |
| 1980 | SLN | Springfield Redbirds | Amer | AAA | team page | 136 | 75 | 61 | -- | 640 | 550 | 90 | 1 | 2 | Hal Lanier | Lanphier Park | League Champions |
| 1980 | SLN | Arkansas Travelers | Tex | AA | team page | 136 | 81 | 55 | -- | 629 | 528 | 101 | 1 | 1 | Sonny Ruberto | Ray Winder Field | League Champions |
| 1980 | SLN | St. Petersburg Cardinals | FSL | A+ | team page | 136 | 70 | 66 | 15.5 | 531 | 558 | -27 | 2 | 4 | Tommy Thompson | Al Lang Field | dnq |
| 1980 | SLN | Gastonia Cardinals | SAL | A | team page | 140 | 74 | 66 | 8.5 | 713 | 673 | 40 | 2 | 4 | Nick Leyva | Sims Legion Park | Lost in Semi-Finals |
| 1980 | SLN | Johnson City Cardinals | App | Rk | team page | 69 | 29 | 40 | 16.5 | 332 | 404 | -72 | 6 | 6 | Johnny Lewis | Howard Johnson Field | dnq |
| 1980 | TEX | Texas Rangers | MLB-AL | MLB | team page | 161 | 76 | 85 | 20.5 | 756 | 752 | 4 | 4 | 10 | Pat Corrales | Arlington Stadium | dnq |
| 1980 | TEX | Charleston Charlies | IL | AAA | team page | 138 | 67 | 71 | 15.0 | 537 | 606 | -69 | 5 | 5 | Tom Burgess | Walt Powell Park | dnq |
| 1980 | TEX | Tulsa Drillers | Tex | AA | team page | 136 | 75 | 61 | 6.0 | 700 | 656 | 44 | 2 | 3 | Wayne Terwilliger | Oiler Park | dnq |
| 1980 | TEX | Asheville Tourists | SAL | A | team page | 140 | 69 | 71 | 13.5 | 735 | 764 | -29 | 3 | 5 | Tom Robson | McCormick Field | dnq |
| 1980 | TEX | Gulf Coast Rangers | GCL | Rk | team page | 63 | 35 | 28 | 5.0 | 310 | 246 | 64 | 4 | 4 | Andy Hancock | Payne Park | dnq |
| 1980 | TOR | Toronto Blue Jays | MLB-AL | MLB | team page | 162 | 67 | 95 | 36.0 | 624 | 762 | -138 | 7 | 12 | Bobby Mattick | Exhibition Stadium | dnq |
| 1980 | TOR | Syracuse Chiefs | IL | AAA | team page | 139 | 58 | 81 | 24.5 | 540 | 591 | -51 | 8 | 8 | Harry Werner | MacArthur Stadium | dnq |
| 1980 | TOR | Knoxville Blue Jays | Sou | AA | team page | 144 | 57 | 87 | 20.0 | 565 | 714 | -149 | 5 | 10 | Duane Larson | Bill Meyer Stadium | dnq |
| 1980 | TOR | Kinston Eagles | Caro | A+ | team page | 138 | 69 | 69 | 14.0 | 645 | 616 | 29 | 3 | 6 | Dennis Holmberg | Grainger Stadium | dnq |
| 1980 | TOR | Utica Blue Jays | NYPL | A- | team page | 71 | 27 | 44 | 20.5 | 370 | 474 | -104 | 4 | 8 | Larry Hardy | Donovan Stadium at Murnane Field | dnq |
| 1980 | TOR | Medicine Hat Blue Jays | Pio | Rk | team page | 70 | 16 | 54 | 36.0 | 247 | 510 | -263 | 4 | 8 | John McLaren | Athletic Park | dnq |