| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 38 | Bryan Gonzalez | 19 | LF | R | 99 | 39 | 139 | 28 | 32 | 5 | 1 | 5 | 27 | 8 | 0 | 19 | 54 | 1 | 0 | 2 | 0 | 0 | 54 | 161 | 11 | 21 | .230 | .323 | .388 | .711 | .353 | .158 | .329 | 11.80 | 33.54 | 2.84 | 27.80 | 2018- UDFA -BOS | premium | premium | premium | AA | 2019-2025 | 2021 | |
| 3 | Brainer Bonaci | 18 | SS | B | 108 | 36 | 139 | 27 | 35 | 13 | 1 | 2 | 17 | 12 | 0 | 21 | 37 | 2 | 0 | 0 | 0 | 2 | 56 | 162 | 16 | 19 | .252 | .358 | .403 | .761 | .388 | .151 | .330 | 12.96 | 22.84 | 1.76 | 69.50 | 2018- UDFA -BOS | premium | premium | premium | AA | 2019-2023 | 2021 | |
| 24 | Miguel Ugueto | 18 | RF-LF | R | 120 | 35 | 127 | 26 | 42 | 15 | 2 | 2 | 20 | 7 | 1 | 7 | 26 | 1 | 0 | 0 | 0 | 0 | 67 | 135 | 19 | 23 | .331 | .370 | .528 | .898 | .299 | .197 | .404 | 5.19 | 19.26 | 3.71 | 63.50 | 2019- UDFA -BOS | premium | premium | premium | AA | 2021-2026 | 2021 | |
| 20 | Eddinson Paulino | 18 | 3B-2B | L | 130 | 36 | 113 | 25 | 38 | 16 | 4 | 0 | 13 | 5 | 2 | 15 | 21 | 5 | 0 | 0 | 0 | 0 | 62 | 133 | 20 | 18 | .336 | .436 | .549 | .985 | .372 | .213 | .413 | 11.28 | 15.79 | 1.40 | 0.00 | 2018- UDFA -BOS | premium | premium | premium | AA | 2019-2026 | 2021 | |
| 55 | Freddy Valdez | 19 | RF | R | 95 | 31 | 96 | 18 | 22 | 6 | 2 | 0 | 16 | 0 | 0 | 18 | 27 | 2 | 0 | 2 | 0 | 1 | 32 | 118 | 8 | 14 | .229 | .356 | .333 | .689 | .292 | .104 | .310 | 15.25 | 22.88 | 1.50 | 0.00 | 2018- UDFA -NYN | premium | premium | premium | Rk | 2019-2022 | 2021 | |
| 18 | Marcelo Mayer | 18 | SS | L | 113 | 26 | 91 | 25 | 25 | 4 | 1 | 3 | 17 | 7 | 1 | 15 | 27 | 0 | 0 | 0 | 0 | 1 | 40 | 106 | 8 | 17 | .275 | .377 | .440 | .817 | .396 | .165 | .361 | 14.15 | 25.47 | 1.80 | 30.33 | 2021- 1- 4-BOS | premium | premium | premium | MLB | 2025-2026 | 2021-2026 | 2021 |
| 22 | Karson Simas | 20 | 2B | R | 115 | 30 | 87 | 17 | 27 | 6 | 2 | 1 | 18 | 4 | 0 | 8 | 22 | 2 | 1 | 0 | 0 | 1 | 40 | 98 | 9 | 18 | .310 | .381 | .460 | .841 | .287 | .150 | .406 | 8.16 | 22.45 | 2.75 | 87.00 | 2019- 25- 767-BOS | premium | premium | premium | AAA | 2019-2026 | 2021 | |
| 15 | Eduardo Vaughan | 19 | CF | R | 107 | 28 | 84 | 16 | 19 | 6 | 0 | 3 | 18 | 5 | 0 | 18 | 24 | 1 | 0 | 2 | 0 | 1 | 34 | 105 | 9 | 10 | .226 | .362 | .405 | .767 | .452 | .179 | .271 | 17.14 | 22.86 | 1.33 | 28.00 | 2018- UDFA -BOS | premium | premium | premium | A | 2019-2022 | 2021 | |
| 29 | Darel Belen | 21 | 1B | R | 90 | 25 | 77 | 11 | 16 | 6 | 0 | 0 | 8 | 4 | 2 | 15 | 34 | 2 | 0 | 1 | 0 | 1 | 22 | 95 | 6 | 10 | .208 | .347 | .286 | .633 | .299 | .078 | .364 | 15.79 | 35.79 | 2.27 | 0.00 | 2019- UDFA -BOS | premium | premium | premium | A | 2019-2022 | 2021 | |
| 17 | Danny Diaz | 20 | 1B | R | 79 | 22 | 75 | 10 | 13 | 5 | 0 | 2 | 12 | 1 | 1 | 9 | 25 | 1 | 0 | 2 | 0 | 1 | 24 | 87 | 7 | 6 | .173 | .264 | .320 | .584 | .267 | .147 | .220 | 10.34 | 28.74 | 2.78 | 37.50 | 2017- UDFA -BOS | premium | premium | premium | Rk | 2018-2021 | 2021 | |
| 58 | Phillip Sikes | 22 | CF | R | 144 | 24 | 74 | 18 | 29 | 8 | 0 | 3 | 18 | 5 | 1 | 8 | 24 | 2 | 0 | 0 | 0 | 1 | 46 | 84 | 11 | 18 | .392 | .464 | .622 | 1.086 | .392 | .230 | .553 | 9.52 | 28.57 | 3.00 | 24.67 | 2021- 18- 526-BOS | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 44 | Blaze Jordan | 18 | 3B | R | 138 | 19 | 69 | 12 | 25 | 7 | 1 | 4 | 19 | 1 | 0 | 6 | 13 | 0 | 0 | 1 | 1 | 2 | 46 | 76 | 12 | 13 | .362 | .408 | .667 | 1.075 | .406 | .305 | .396 | 7.89 | 17.11 | 2.17 | 17.25 | 2020- 3- 89-BOS | premium | premium | premium | AAA | 2021-2026 | 2021 | |
| 50 | Tyler Miller | 21 | 3B | L | 118 | 18 | 62 | 9 | 19 | 5 | 1 | 1 | 12 | 2 | 0 | 7 | 16 | 3 | 0 | 0 | 0 | 1 | 29 | 72 | 7 | 12 | .306 | .403 | .468 | .871 | .306 | .162 | .400 | 9.72 | 22.22 | 2.29 | 62.00 | 2021- 9- 256-BOS | premium | premium | premium | AAA | 2020-2025 | 2021 | |
| 37 | Jose Garcia | 23 | C | R | 111 | 19 | 53 | 9 | 14 | 4 | 1 | 1 | 12 | 0 | 0 | 9 | 17 | 3 | 0 | 1 | 0 | 0 | 23 | 66 | 6 | 8 | .264 | .394 | .434 | .828 | .340 | .170 | .361 | 13.64 | 25.76 | 1.89 | 53.00 | 2017- 38-1151-BOS | premium | premium | premium | A+ | 2018-2022 | 2021 | |
| 49 | Cuba Bess | 23 | 1B | L | 126 | 21 | 52 | 12 | 13 | 5 | 2 | 2 | 13 | 1 | 0 | 13 | 20 | 3 | 0 | 1 | 0 | 0 | 28 | 69 | 9 | 4 | .250 | .420 | .538 | .958 | .558 | .288 | .355 | 18.84 | 28.99 | 1.54 | 26.00 | 2016- 39-1160-COL | premium | premium | premium | A+ | 2017-2025 | 2021 | |
| 12 | Albert Feliz | 19 | LF-RF | R | 83 | 20 | 50 | 4 | 9 | 5 | 0 | 0 | 5 | 0 | 1 | 10 | 22 | 0 | 0 | 0 | 0 | 0 | 14 | 60 | 5 | 4 | .180 | .317 | .280 | .597 | .280 | .100 | .321 | 16.67 | 36.67 | 2.20 | 0.00 | 2018- UDFA -BOS | premium | premium | premium | A+ | 2019-2025 | 2021 | |
| 2 | Kier Meredith | 21 | CF-LF | L | 73* | 18 | 45 | 8 | 7 | 0 | 0 | 0 | 0 | 5 | 1 | 8 | 10 | 1 | 0 | 0 | 0 | 0 | 7 | 54 | 0 | 7 | .156 | .296 | .156 | .452 | .267 | .000 | .200 | 14.81 | 18.52 | 1.25 | 0.00 | 2017- 28- 855-CHN | premium | premium | premium | A+ | 2018-2023 | 2021 | |
| 25 | Yorberto Mejicano | 20 | C | R | 141* | 18 | 41 | 11 | 17 | 2 | 0 | 3 | 13 | 0 | 1 | 6 | 10 | 0 | 0 | 3 | 0 | 0 | 28 | 50 | 5 | 12 | .415 | .460 | .683 | 1.143 | .390 | .268 | .452 | 12.00 | 20.00 | 1.67 | 13.67 | 2019- UDFA -BOS | premium | premium | premium | A | 2019-2023 | 2021 | |
| 23 | Juan Montero | 19 | C | R | 97* | 16 | 39 | 6 | 7 | 3 | 0 | 1 | 9 | 1 | 1 | 11 | 13 | 0 | 0 | 0 | 0 | 0 | 13 | 50 | 4 | 3 | .179 | .360 | .333 | .693 | .436 | .154 | .240 | 22.00 | 26.00 | 1.18 | 39.00 | 2020- UDFA -BOS | premium | premium | premium | AA | 2021-2025 | 2021 | |
| 5 | B.J. Vela | 21 | 2B-3B | R | 80* | 11 | 32 | 5 | 7 | 0 | 0 | 1 | 4 | 1 | 0 | 2 | 10 | 0 | 0 | 0 | 0 | 1 | 10 | 34 | 1 | 6 | .219 | .265 | .313 | .578 | .188 | .094 | .286 | 5.88 | 29.41 | 5.00 | 32.00 | 2021- 16- 466-BOS | premium | premium | premium | Rk | 2021-2022 | 2021 | |
| 2 | Antoni Flores | 20 | 2B | R | 87* | 8 | 27 | 4 | 6 | 0 | 0 | 0 | 2 | 0 | 0 | 6 | 9 | 0 | 0 | 0 | 0 | 0 | 6 | 33 | 0 | 6 | .222 | .364 | .222 | .586 | .222 | .000 | .333 | 18.18 | 27.27 | 1.50 | 0.00 | 2017- UDFA -BOS | premium | premium | premium | A+ | 2018-2022 | 2021 | |
| 39 | Naysbel Marcano | 19 | C | R | 13 | 27 | 4 | 8 | 2 | 0 | 0 | 2 | 0 | 0 | 1 | 9 | 1 | 0 | 0 | 1 | 0 | 10 | 29 | 2 | 6 | .296 | .345 | .370 | .715 | .111 | .074 | .444 | 3.45 | 31.03 | 9.00 | 0.00 | 2018- UDFA -BOS | premium | premium | premium | Rk | 2019-2022 | 2021 | ||
| 60 | Daniel McElveny | 18 | 2B | R | 90* | 9 | 23 | 5 | 4 | 1 | 0 | 0 | 1 | 0 | 0 | 3 | 10 | 4 | 1 | 0 | 0 | 1 | 5 | 31 | 1 | 3 | .174 | .367 | .217 | .584 | .174 | .043 | .308 | 9.68 | 32.26 | 3.33 | 0.00 | 2021- 6- 166-BOS | premium | premium | premium | A | 2021-2025 | 2021 | |
| 35 | Niko Kavadas | 22 | 1B | L | 8 | 22 | 4 | 5 | 2 | 0 | 1 | 2 | 0 | 0 | 7 | 6 | 0 | 0 | 0 | 0 | 0 | 10 | 29 | 3 | 2 | .227 | .414 | .455 | .869 | .545 | .228 | .267 | 24.14 | 20.69 | 0.86 | 22.00 | 2021- 11- 316-BOS | premium | premium | premium | MLB | 2024-2025 | 2018-2026 | 2021 | |
| 44 | Nathan Hickey | 21 | C | L | 8 | 20 | 4 | 5 | 2 | 0 | 0 | 1 | 0 | 0 | 6 | 8 | 1 | 0 | 1 | 0 | 0 | 7 | 28 | 2 | 3 | .250 | .429 | .350 | .779 | .400 | .100 | .385 | 21.43 | 28.57 | 1.33 | 0.00 | 2021- 5- 136-BOS | premium | premium | premium | AAA | 2020-2026 | 2021 | ||
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 41 | Jonathan Diaz | 21 | C | L | 6 | 16 | 0 | 4 | 4 | 0 | 0 | 8 | 0 | 1 | 3 | 4 | 0 | 1 | 0 | 0 | 1 | 8 | 20 | 4 | 0 | .250 | .368 | .500 | .868 | .375 | .250 | .333 | 15.00 | 20.00 | 1.33 | 0.00 | 2017- UDFA -BOS | premium | premium | premium | A+ | 2017-2023 | 2021 | ||
| - | Ricardo Cubillan | 23 | 3B | B | 4 | 13 | 3 | 6 | 0 | 0 | 0 | 3 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 6 | 14 | 0 | 6 | .462 | .500 | .462 | .962 | .154 | .000 | .600 | 7.14 | 21.43 | 3.00 | 0.00 | 2014- UDFA -BOS | premium | premium | premium | AAA | 2016-2022 | 2021 | ||
| 1 | Nick Decker | 21 | LF | L | 5 | 13 | 1 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 2 | 17 | 0 | 2 | .154 | .353 | .154 | .507 | .308 | .000 | .222 | 23.53 | 23.53 | 1.00 | 0.00 | 2018- 2- 64-BOS | premium | premium | premium | AA | 2018-2025 | 2021 | ||
| - | Tyler McDonough | 22 | 2B-CF | B | 4 | 13 | 2 | 4 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 7 | 13 | 3 | 1 | .308 | .308 | .538 | .846 | .231 | .230 | .444 | 0.00 | 30.77 | 0.00 | 0.00 | 2021- 3- 75-BOS | premium | premium | premium | AAA | 2019-2026 | 2021 | ||
| 40 | Bramdon Perez | 21 | RF-CF | L | 6 | 13 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 3 | 14 | 1 | 1 | .154 | .214 | .231 | .445 | .154 | .077 | .286 | 7.14 | 42.86 | 6.00 | 0.00 | 2018- 32- 970-BOS | premium | premium | premium | Rk | 2018-2022 | 2021 | ||
| 18 | Angel Maita | 20 | LF-CF | B | 4 | 11 | 2 | 3 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 6 | 11 | 1 | 2 | .273 | .273 | .545 | .818 | .273 | .272 | .333 | 0.00 | 36.36 | 0.00 | 11.00 | 2017- UDFA -BOS | premium | premium | premium | A | 2018-2021 | 2021 | ||
| 10 | Leon Paulino | 20 | RF-LF | B | 5 | 8 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 9 | 0 | 1 | .125 | .222 | .125 | .347 | .125 | .000 | .250 | 11.11 | 44.44 | 4.00 | 0.00 | 2019- 23- 707-BOS | premium | premium | premium | Rk | 2019-2025 | 2021 | ||
| - | Eduardo Lopez | 19 | LF-CF | B | 2 | 6 | 1 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6 | 0 | 2 | .333 | .333 | .333 | .666 | .000 | .000 | .333 | 0.00 | 0.00 | 0.00 | 0.00 | 2018- UDFA -BOS | premium | premium | premium | A+ | 2019-2025 | 2021 | ||
| 54 | Jacob Herbert | 21 | C-P | R | 3 | 5 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3 | 5 | 1 | 1 | .400 | .400 | .600 | 1.000 | .200 | .200 | 1.000 | 0.00 | 60.00 | 0.00 | 0.00 | 2019- 18- 557-BOS | premium | premium | premium | Rk | 2019-2021 | 2021 | ||
| Totals: | 577 | 1762 | 332 | 470 | 137 | 18 | 36 | 299 | 70 | 13 | 258 | 526 | 35 | 3 | 16 | 2 | 16 | 751 | 2074 | 191 | 279 | .267 | .368 | .426 | .795 | .338 | .159 | .357 | 12.44 | 25.36 | 2.04 | 48.94 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 71 | Juan Daniel Encarnacion | 20 | R | 2 | 1 | 2.96 | 12 | 10 | 0 | 0 | 2 | 1 | 0 | 45.2 | 34 | 17 | 15 | 7 | 11 | 56 | 1 | 0 | 3 | 0.99 | 6.70 | 1.38 | 2.17 | 11.04 | 3.35 | 5.09 | 2018- UDFA -BOS | premium | premium | premium | AA | 2019-2024 | 2021 | |
| 46 | Wikelman Gonzalez | 19 | R | 4 | 2 | 3.60 | 8 | 7 | 1 | 0 | 1 | 0 | 0 | 35.0 | 29 | 16 | 14 | 1 | 8 | 46 | 0 | 0 | 3 | 1.06 | 7.46 | 0.26 | 2.06 | 11.83 | 4.11 | 5.75 | 2018- UDFA -BOS | premium | premium | premium | MLB | 2025-2025 | 2019-2026 | 2021 |
| 64 | Henry Nunez | 20 | R | 2 | 2 | 6.23 | 9 | 4 | 0 | 0 | 5 | 0 | 0 | 30.1 | 26 | 23 | 21 | 5 | 20 | 46 | 7 | 1 | 5 | 1.52 | 7.71 | 1.48 | 5.93 | 13.65 | 6.82 | 2.30 | premium | premium | premium | Rk | 2021-2022 | 2021 | ||
| 64 | Angel Bastardo | 19 | R | 1 | 3 | 6.67 | 10 | 6 | 0 | 0 | 4 | 0 | 0 | 29.2 | 45 | 29 | 22 | 1 | 12 | 33 | 8 | 0 | 0 | 1.92 | 13.65 | 0.30 | 3.64 | 10.01 | 8.80 | 2.75 | 2018- UDFA -BOS | premium | premium | premium | AAA | 2019-2026 | 2021 | |
| 56 | Luis De La Rosa | 18 | R | 1 | 0 | 3.04 | 8 | 5 | 0 | 0 | 3 | 1 | 1 | 26.2 | 19 | 9 | 9 | 1 | 9 | 21 | 1 | 1 | 4 | 1.05 | 6.41 | 0.34 | 3.04 | 7.09 | 3.04 | 2.33 | 2018- UDFA -KCA | premium | premium | premium | A | 2019-2024 | 2021 | |
| 30 | Reidis Sena | 20 | R | 1 | 0 | 3.22 | 9 | 3 | 0 | 0 | 6 | 2 | 0 | 22.1 | 22 | 8 | 8 | 1 | 13 | 31 | 2 | 0 | 1 | 1.57 | 8.87 | 0.40 | 5.24 | 12.49 | 3.22 | 2.38 | 2018- UDFA -BOS | premium | premium | premium | AAA | 2019-2026 | 2021 | |
| 59 | Felix Cepeda | 20 | R | 1 | 2 | 4.64 | 6 | 5 | 0 | 0 | 1 | 0 | 0 | 21.1 | 18 | 15 | 11 | 2 | 18 | 26 | 5 | 0 | 2 | 1.69 | 7.59 | 0.84 | 7.59 | 10.97 | 6.33 | 1.44 | 2017- UDFA -BOS | premium | premium | premium | AA | 2018-2026 | 2021 | |
| 67 | Cole Milam | 23 | R | 1 | 0 | 2.14 | 11 | 0 | 0 | 0 | 11 | 3 | 1 | 21.0 | 10 | 9 | 5 | 0 | 13 | 28 | 9 | 2 | 1 | 1.10 | 4.29 | 0.00 | 5.57 | 12.00 | 3.86 | 2.15 | 2020- UDFA -BOS | premium | premium | premium | A | 2017-2021 | 2021 | |
| 62 | Gabriel Jackson | 19 | R | 2 | 0 | 3.57 | 10 | 2 | 0 | 0 | 8 | 1 | 0 | 17.2 | 15 | 9 | 7 | 1 | 11 | 17 | 2 | 0 | 0 | 1.47 | 7.64 | 0.51 | 5.60 | 8.66 | 4.58 | 1.55 | 2018- UDFA -BOS | premium | premium | premium | AAA | 2019-2025 | 2021 | |
| 61 | Jose Larez | 24 | R | 5 | 0 | 2.04 | 9 | 0 | 0 | 0 | 9 | 3 | 0 | 17.2 | 14 | 6 | 4 | 2 | 6 | 24 | 1 | 0 | 0 | 1.13 | 7.13 | 1.02 | 3.06 | 12.23 | 3.06 | 4.00 | 2017- UDFA -BOS | premium | premium | premium | A | 2017-2021 | 2021 | |
| 63 | Merfy Andrew | 24 | R | 4 | 1 | 7.41 | 18 | 0 | 0 | 0 | 18 | 15 | 5 | 17.0 | 19 | 15 | 14 | 1 | 7 | 15 | 6 | 0 | 0 | 1.53 | 10.06 | 0.53 | 3.71 | 7.94 | 7.94 | 2.14 | 2020- UDFA -BOS | premium | premium | premium | A | 2021-2024 | 2021 | |
| 70 | Blake Loubier | 20 | R | 2 | 4 | 9.00 | 8 | 1 | 0 | 0 | 7 | 3 | 0 | 14.0 | 21 | 14 | 14 | 3 | 7 | 16 | 4 | 1 | 1 | 2.00 | 13.50 | 1.93 | 4.50 | 10.29 | 9.00 | 2.29 | 2019- 13- 407-BOS | premium | premium | premium | A | 2019-2024 | 2021 | |
| 51 | Gregori Segovia | 21 | R | 3 | 0 | 3.86 | 13 | 0 | 0 | 0 | 13 | 3 | 0 | 14.0 | 9 | 8 | 6 | 1 | 8 | 15 | 1 | 1 | 0 | 1.21 | 5.79 | 0.64 | 5.14 | 9.64 | 5.14 | 1.88 | premium | premium | premium | Rk | 2018-2021 | 2021 | ||
| 57 | Ryan Zeferjahn | 23 | R | 0 | 0 | 3.21 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 14.0 | 12 | 6 | 5 | 2 | 3 | 18 | 2 | 0 | 1 | 1.07 | 7.71 | 1.29 | 1.93 | 11.57 | 3.86 | 6.00 | 2019- 3- 107-BOS | premium | premium | premium | MLB | 2024-2026 | 2017-2026 | 2021 |
| 32 | Joey Stock | 23 | R | 1 | 0 | 2.70 | 9 | 0 | 0 | 0 | 9 | 6 | 1 | 13.1 | 8 | 5 | 4 | 1 | 3 | 17 | 0 | 0 | 0 | 0.83 | 5.40 | 0.68 | 2.03 | 11.48 | 3.38 | 5.67 | 2020- UDFA -BOS | premium | premium | premium | A+ | 2017-2023 | 2021 | |
| 52 | Maceo Campbell | 22 | R | 1 | 0 | 2.19 | 11 | 0 | 0 | 0 | 11 | 3 | 1 | 12.1 | 7 | 3 | 3 | 0 | 8 | 16 | 2 | 1 | 2 | 1.22 | 5.11 | 0.00 | 5.84 | 11.68 | 2.19 | 2.00 | premium | premium | premium | A+ | 2018-2025 | 2021 | ||
| 48 | Bryan Lucas | 23 | R | 1 | 0 | 2.92 | 7 | 0 | 0 | 0 | 7 | 2 | 1 | 12.1 | 14 | 8 | 4 | 2 | 2 | 15 | 1 | 0 | 1 | 1.30 | 10.22 | 1.46 | 1.46 | 10.95 | 5.84 | 7.50 | 2017- UDFA -BOS | premium | premium | premium | A+ | 2018-2022 | 2021 | |
| 16 | Osvaldo De La Rosa | 23 | R | 0 | 0 | 6.94 | 8 | 0 | 0 | 0 | 8 | 3 | 0 | 11.2 | 14 | 13 | 9 | 5 | 4 | 8 | 2 | 0 | 0 | 1.54 | 10.80 | 3.86 | 3.09 | 6.17 | 10.03 | 2.00 | 2018- UDFA -BOS | premium | premium | premium | A | 2018-2022 | 2021 | |
| 88 | Nate Tellier | 23 | R | 1 | 1 | 2.00 | 6 | 0 | 0 | 0 | 6 | 3 | 1 | 9.0 | 3 | 2 | 2 | 0 | 5 | 14 | 1 | 0 | 1 | 0.89 | 3.00 | 0.00 | 5.00 | 14.00 | 2.00 | 2.80 | 2020- UDFA -BOS | premium | premium | premium | A+ | 2017-2024 | 2021 | |
| 41 | Tyler Uberstine | 22 | R | 0 | 1 | 1.17 | 5 | 1 | 0 | 0 | 4 | 1 | 1 | 7.2 | 4 | 3 | 1 | 0 | 1 | 8 | 0 | 0 | 0 | 0.65 | 4.70 | 0.00 | 1.17 | 9.39 | 3.52 | 8.00 | 2021- 19- 556-BOS | premium | premium | premium | MLB | 2026-2026 | 2020-2026 | 2021 |
| - | Colten Brewer | 28 | R | 1 | 0 | 4.91 | 4 | 1 | 0 | 0 | 3 | 0 | 0 | 7.1 | 7 | 4 | 4 | 0 | 3 | 9 | 2 | 0 | 2 | 1.36 | 8.59 | 0.00 | 3.68 | 11.05 | 4.91 | 3.00 | 2011- 4- 122-PIT | premium | premium | premium | MLB | 2018-2024 | 2012-2025 | 2021 |
| 43 | Nathanael Cruz | 18 | R | 0 | 0 | 3.18 | 4 | 3 | 0 | 0 | 1 | 0 | 0 | 5.2 | 4 | 2 | 2 | 2 | 3 | 8 | 0 | 0 | 1 | 1.24 | 6.35 | 3.18 | 4.76 | 12.71 | 3.18 | 2.67 | 2019- UDFA -BOS | premium | premium | premium | A | 2021-2025 | 2021 | |
| - | Connor Seabold | 25 | R | 0 | 0 | 3.18 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 5.2 | 3 | 2 | 2 | 0 | 3 | 12 | 3 | 0 | 1 | 1.06 | 4.76 | 0.00 | 4.76 | 19.06 | 3.18 | 4.00 | 2017- 3- 83-PHI | premium | premium | premium | MLB | 2021-2026 | 2015-2026 | 2021 |
| 58 | Chih-Jung Liu | 22 | R | 0 | 0 | 3.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 5.0 | 3 | 2 | 2 | 2 | 0 | 6 | 0 | 0 | 0 | 0.60 | 5.40 | 3.60 | 0.00 | 10.80 | 3.60 | 0.00 | 2019- UDFA -BOS | premium | premium | premium | AA | 2021-2024 | 2021 | |
| 88 | Michael Gettys | 25 | R | 1 | 0 | 3.60 | 5 | 0 | 0 | 0 | 5 | 0 | 0 | 5.0 | 5 | 2 | 2 | 1 | 4 | 5 | 1 | 0 | 0 | 1.80 | 9.00 | 1.80 | 7.20 | 9.00 | 3.60 | 1.25 | 2014- 2- 51-SDN | premium | premium | premium | AAA | 2014-2022 | 2021 | |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| - | Miguel Suero | 24 | R | 0 | 0 | 0.00 | 3 | 0 | 0 | 0 | 3 | 2 | 1 | 4.2 | 3 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0.64 | 5.79 | 0.00 | 0.00 | 7.71 | 1.93 | 0.00 | 2017- UDFA -BOS | premium | premium | premium | A | 2018-2022 | 2021 | |
| 28 | Eduard Bazardo | 25 | R | 1 | 0 | 0.00 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 4.0 | 2 | 0 | 0 | 0 | 1 | 9 | 0 | 0 | 0 | 0.75 | 4.50 | 0.00 | 2.25 | 20.25 | 0.00 | 9.00 | 2014- UDFA -BOS | premium | premium | premium | MLB | 2021-2026 | 2015-2026 | 2021 |
| 19 | Adenys Bautista | 22 | R | 0 | 1 | 10.80 | 3 | 0 | 0 | 0 | 3 | 1 | 0 | 3.1 | 5 | 4 | 4 | 1 | 3 | 4 | 1 | 0 | 0 | 2.40 | 13.50 | 2.70 | 8.10 | 10.80 | 10.80 | 1.33 | 2018- UDFA -CLE | premium | premium | premium | A | 2018-2022 | 2021 | |
| - | Chris Sale | 32 | L | 0 | 0 | 0.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 3.0 | 4 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 1.33 | 12.00 | 0.00 | 0.00 | 15.00 | 0.00 | 0.00 | 2010- 1- 13-CHA | premium | premium | premium | MLB | 2010-2026 | 2008-2026 | 2021 |
| 40 | Jhonny Felix | 22 | R | 0 | 1 | 30.00 | 5 | 0 | 0 | 0 | 5 | 1 | 0 | 3.0 | 7 | 10 | 10 | 1 | 6 | 6 | 1 | 0 | 2 | 4.33 | 21.00 | 3.00 | 18.00 | 18.00 | 30.00 | 1.00 | 2019- 21- 621-MIA | premium | premium | premium | A | 2020-2023 | 2021 | |
| - | Zach Schellenger | 25 | R | 1 | 0 | 0.00 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 2.1 | 0 | 0 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 0.43 | 0.00 | 0.00 | 3.86 | 23.14 | 0.00 | 6.00 | 2017- 6- 191-BOS | premium | premium | premium | AA | 2015-2021 | 2021 | |
| - | Jacob Webb | 22 | R | 0 | 0 | 0.00 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 2.0 | 1 | 1 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0.50 | 4.50 | 0.00 | 0.00 | 22.50 | 4.50 | 0.00 | 2021- 14- 406-BOS | premium | premium | premium | AAA | 2019-2026 | 2021 | |
| 80 | Christopher Troye | 22 | R | 0 | 0 | 4.50 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 2.0 | 2 | 1 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | 1.00 | 9.00 | 0.00 | 0.00 | 22.50 | 4.50 | 0.00 | 2021- 12- 346-BOS | premium | premium | premium | AA | 2018-2025 | 2021 | |
| - | Jose De Leon | 28 | R | 0 | 1 | 9.00 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 2.0 | 3 | 2 | 2 | 1 | 0 | 4 | 0 | 0 | 0 | 1.50 | 13.50 | 4.50 | 0.00 | 18.00 | 9.00 | 0.00 | 2013- 24- 724-LAN | premium | premium | premium | MLB | 2016-2025 | 2011-2025 | 2021 |
| 54 | Jacob Herbert | 21 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 6.75 | 0.00 | 0.00 | 2019- 18- 557-BOS | premium | premium | premium | Rk | 2019-2021 | 2021 | |
| 60 | Jose Disla | 25 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.00 | 9.00 | 0.00 | 9.00 | 0.00 | 0.00 | 0.00 | 2013- UDFA -TBA | premium | premium | premium | AA | 2013-2021 | 2021 | |
| - | Wyatt Olds | 21 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 2.00 | 9.00 | 0.00 | 9.00 | 9.00 | 0.00 | 1.00 | 2021- 7- 196-BOS | premium | premium | premium | AAA | 2019-2026 | 2021 | |
| 40 | Bramdon Perez | 21 | R | 0 | 0 | 40.50 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0.2 | 2 | 3 | 3 | 0 | 4 | 0 | 0 | 0 | 0 | 9.00 | 27.00 | 0.00 | 54.00 | 0.00 | 40.50 | 0.00 | 2018- 32- 970-BOS | premium | premium | premium | Rk | 2018-2022 | 2021 | |
| 12 | Albert Feliz | 19 | R | 0 | 0 | 13.50 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0.2 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1.50 | 13.50 | 13.50 | 0.00 | 13.50 | 13.50 | 0.00 | 2018- UDFA -BOS | premium | premium | premium | A+ | 2019-2025 | 2021 | |
| Totals: | 37 | 20 | 4.20 | 225 | 57 | 1 | 0 | 56 | 168 | 13 | 452.1 | 397 | 253 | 211 | 45 | 199 | 561 | 63 | 7 | 31 | 1.32 | 7.90 | 0.90 | 3.96 | 11.16 | 5.03 | 2.82 | premium | premium | premium |