| Central | W | L | Pct | GB |
| Detroit | 88 | 74 | .543 | -- |
| Chi White Sox | 85 | 77 | .525 | 3.0 |
| KC Royals | 72 | 90 | .444 | 16.0 |
| Cleveland | 68 | 94 | .420 | 20.0 |
| Minnesota | 66 | 96 | .407 | 22.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2012-04-06 | Carl Pavano | R | 36 | L 2-4 | @ BAL | 1 | 274 | L | 7.0 | 5 | 4 | 4 | 1 | 2 | 1 | 93 | 40 | 53 | 57% | 0-1 | 5.14 | 1.00 |
| 2012-04-07 | Francisco Liriano | L | 28 | L 2-8 | @ BAL | 1 | 114 | L | 4.0 | 8 | 6 | 5 | 1 | 2 | 4 | 74 | 29 | 45 | 61% | 0-1 | 11.25 | 2.50 |
| 2012-04-08 | Anthony Swarzak | R | 27 | L 1-3 | @ BAL | 1 | 24 | L | 5.0 | 4 | 1 | 1 | 1 | 2 | 1 | 82 | 33 | 49 | 60% | 0-1 | 1.80 | 1.20 |
| 2012-04-09 | Nick Blackburn | R | 30 | W 1-5 | vs ANA | 1 | 119 | L | 6.0 | 5 | 5 | 5 | 0 | 2 | 3 | 97 | 39 | 58 | 60% | 0-1 | 7.50 | 1.17 |
| 2012-04-11 | Carl Pavano | R | 36 | L 6-5 | vs ANA | 2 | 275 | - | 6.2 | 7 | 5 | 5 | 1 | 0 | 3 | 100 | 28 | 72 | 72% | 0-1 | 5.79 | 1.00 |
| 2012-04-12 | Francisco Liriano | L | 28 | L 10-9 | vs ANA | 2 | 115 | - | 5.0 | 7 | 6 | 5 | 1 | 3 | 2 | 91 | 35 | 56 | 62% | 0-1 | 10.00 | 2.22 |
| 2012-04-13 | Anthony Swarzak | R | 27 | W 1-4 | vs TEX | 2 | 25 | L | 7.0 | 9 | 4 | 4 | 1 | 0 | 3 | 95 | 29 | 66 | 69% | 0-2 | 3.75 | 1.25 |
| 2012-04-14 | Nick Blackburn | R | 30 | W 2-6 | vs TEX | 2 | 120 | - | 5.1 | 7 | 2 | 2 | 1 | 1 | 3 | 75 | 26 | 49 | 65% | 0-1 | 5.73 | 1.36 |
| 2012-04-15 | Liam Hendriks | R | 23 | W 3-4 | vs TEX | 1 | 5 | - | 6.0 | 7 | 1 | 1 | 1 | 0 | 4 | 84 | 27 | 57 | 68% | 0-0 | 1.50 | 1.17 |
| 2012-04-16 | Carl Pavano | R | 36 | W 7-3 | @ NYA | 3 | 276 | W | 7.0 | 7 | 3 | 3 | 2 | 1 | 6 | 97 | 38 | 59 | 61% | 1-1 | 5.14 | 1.05 |
| 2012-04-17 | Francisco Liriano | L | 28 | L 3-8 | @ NYA | 3 | 116 | L | 2.1 | 7 | 5 | 5 | 0 | 4 | 2 | 78 | 41 | 37 | 47% | 0-2 | 12.27 | 2.82 |
| 2012-04-18 | Jason Marquis | R | 34 | W 6-5 | @ NYA | 1 | 268 | W | 5.0 | 7 | 4 | 4 | 1 | 2 | 3 | 87 | 37 | 50 | 57% | 1-0 | 7.20 | 1.80 |
| 2012-04-19 | Anthony Swarzak | R | 27 | L 6-7 | @ NYA | 3 | 26 | L | 2.2 | 8 | 6 | 6 | 3 | 1 | 3 | 64 | 24 | 40 | 63% | 0-3 | 6.60 | 1.60 |
| 2012-04-20 | Liam Hendriks | R | 23 | W 5-4 | @ TBA | 2 | 6 | - | 5.2 | 5 | 4 | 4 | 2 | 2 | 1 | 107 | 50 | 57 | 53% | 0-0 | 3.75 | 1.17 |
| 2012-04-21 | Carl Pavano | R | 36 | L 1-4 | @ TBA | 4 | 277 | L | 6.0 | 7 | 3 | 2 | 0 | 2 | 7 | 109 | 40 | 69 | 63% | 1-2 | 4.67 | 1.15 |
| 2012-04-22 | Francisco Liriano | L | 28 | L 2-6 | @ TBA | 4 | 117 | L | 5.0 | 3 | 5 | 5 | 1 | 4 | 4 | 86 | 40 | 46 | 53% | 0-3 | 11.25 | 2.38 |
| 2012-04-23 | Jason Marquis | R | 34 | W 5-6 | vs BOS | 2 | 269 | - | 6.1 | 11 | 5 | 5 | 2 | 0 | 3 | 107 | 38 | 69 | 64% | 1-0 | 7.36 | 1.82 |
| 2012-04-24 | Nick Blackburn | R | 30 | W 2-11 | vs BOS | 3 | 121 | L | 3.0 | 8 | 5 | 5 | 1 | 1 | 2 | 71 | 27 | 44 | 62% | 0-2 | 7.71 | 1.71 |
| 2012-04-25 | Liam Hendriks | R | 23 | W 6-7 | vs BOS | 3 | 7 | L | 4.0 | 9 | 7 | 7 | 1 | 2 | 3 | 87 | 30 | 57 | 66% | 0-1 | 6.75 | 1.56 |
| 2012-04-27 | Carl Pavano | R | 36 | W 6-7 | vs KCA | 5 | 278 | - | 6.1 | 6 | 5 | 4 | 2 | 1 | 0 | 83 | 28 | 55 | 66% | 1-2 | 4.91 | 1.15 |
| 2012-04-29 | Jason Marquis | R | 34 | L 7-4 | vs KCA | 3 | 270 | W | 6.0 | 6 | 3 | 3 | 1 | 0 | 1 | 80 | 31 | 49 | 61% | 2-0 | 6.35 | 1.53 |
| 2012-04-30 | Nick Blackburn | R | 30 | L 3-4 | @ ANA | 4 | 122 | L | 6.0 | 7 | 3 | 3 | 1 | 1 | 2 | 84 | 35 | 49 | 58% | 0-3 | 6.75 | 1.60 |
| 2012-05-01 | Francisco Liriano | L | 29 | L 0-4 | @ ANA | 5 | 118 | L | 5.1 | 7 | 4 | 4 | 2 | 3 | 5 | 98 | 44 | 54 | 55% | 0-4 | 9.82 | 2.18 |
| 2012-05-02 | Liam Hendriks | R | 23 | L 0-9 | @ ANA | 4 | 8 | L | 2.1 | 9 | 6 | 6 | 1 | 0 | 1 | 60 | 26 | 34 | 57% | 0-2 | 9.00 | 1.89 |
| 2012-05-04 | Carl Pavano | R | 36 | W 3-2 | @ SEA | 6 | 279 | W | 6.0 | 8 | 2 | 2 | 0 | 0 | 2 | 67 | 23 | 44 | 66% | 2-2 | 4.62 | 1.18 |
| 2012-05-05 | Jason Marquis | R | 34 | L 0-7 | @ SEA | 4 | 271 | L | 6.0 | 4 | 2 | 2 | 0 | 6 | 1 | 94 | 47 | 47 | 50% | 2-1 | 5.48 | 1.57 |
| 2012-05-06 | Nick Blackburn | R | 30 | L 2-5 | @ SEA | 5 | 123 | L | 6.0 | 7 | 5 | 5 | 1 | 3 | 4 | 97 | 39 | 58 | 60% | 0-4 | 6.92 | 1.62 |
| 2012-05-07 | Francisco Liriano | L | 29 | W 3-8 | vs ANA | 6 | 119 | L | 5.0 | 5 | 4 | 4 | 1 | 3 | 4 | 90 | 40 | 50 | 56% | 0-5 | 9.33 | 2.07 |
| 2012-05-08 | Scott Diamond | L | 26 | L 5-0 | vs ANA | 1 | 8 | W | 7.0 | 4 | 0 | 0 | 0 | 1 | 6 | 102 | 40 | 62 | 61% | 1-0 | 0.00 | 0.71 |
| 2012-05-09 | Carl Pavano | R | 36 | W 2-6 | vs ANA | 7 | 280 | L | 4.0 | 10 | 5 | 4 | 0 | 0 | 1 | 62 | 18 | 44 | 71% | 2-3 | 5.02 | 1.30 |
| 2012-05-10 | Jason Marquis | R | 34 | W 2-6 | vs TOR | 5 | 272 | L | 4.0 | 7 | 6 | 5 | 0 | 3 | 2 | 86 | 39 | 47 | 55% | 2-2 | 6.33 | 1.70 |
| 2012-05-11 | Nick Blackburn | R | 30 | L 7-6 | vs TOR | 6 | 124 | W | 5.0 | 6 | 5 | 5 | 3 | 3 | 3 | 81 | 34 | 47 | 58% | 1-4 | 7.26 | 1.65 |
| 2012-05-12 | P.J. Walters | R | 27 | W 1-2 | vs TOR | 1 | 5 | L | 6.0 | 6 | 2 | 2 | 1 | 0 | 5 | 93 | 32 | 61 | 66% | 0-1 | 3.00 | 1.00 |
| 2012-05-13 | Scott Diamond | L | 26 | L 4-3 | vs TOR | 2 | 9 | W | 7.0 | 5 | 0 | 0 | 0 | 0 | 4 | 100 | 38 | 62 | 62% | 2-0 | 0.00 | 0.71 |
| 2012-05-14 | Carl Pavano | R | 36 | W 4-5 | vs CLE | 8 | 281 | - | 6.0 | 6 | 4 | 4 | 1 | 0 | 3 | 72 | 24 | 48 | 67% | 2-3 | 5.14 | 1.27 |
| 2012-05-15 | Jason Marquis | R | 34 | W 0-5 | vs CLE | 6 | 273 | L | 5.0 | 9 | 5 | 5 | 3 | 2 | 2 | 95 | 36 | 59 | 62% | 2-3 | 6.75 | 1.78 |
| 2012-05-16 | Nick Blackburn | R | 30 | W 11-7 | @ DET | 7 | 125 | - | 2.0 | 6 | 6 | 6 | 0 | 2 | 2 | 53 | 20 | 33 | 62% | 1-4 | 8.45 | 1.79 |
| 2012-05-17 | P.J. Walters | R | 27 | W 4-3 | @ DET | 2 | 6 | W | 6.1 | 4 | 3 | 3 | 3 | 3 | 2 | 87 | 37 | 50 | 57% | 1-1 | 3.75 | 1.08 |
| 2012-05-18 | Scott Diamond | L | 26 | W 11-3 | @ MIL | 3 | 10 | W | 5.1 | 8 | 3 | 3 | 1 | 1 | 3 | 92 | 31 | 61 | 66% | 3-0 | 1.42 | 1.00 |
| 2012-05-19 | Carl Pavano | R | 36 | W 5-4 | @ MIL | 9 | 282 | - | 6.0 | 5 | 2 | 2 | 0 | 1 | 6 | 93 | 30 | 63 | 68% | 2-3 | 4.91 | 1.24 |
| 2012-05-20 | Jason Marquis | R | 34 | L 4-16 | @ MIL | 7 | 274 | L | 1.2 | 8 | 8 | 8 | 2 | 1 | 0 | 48 | 22 | 26 | 54% | 2-4 | 8.47 | 1.94 |
| 2012-05-22 | P.J. Walters | R | 27 | W 9-2 | @ CHA | 3 | 7 | W | 9.0 | 5 | 2 | 2 | 1 | 2 | 8 | 110 | 41 | 69 | 63% | 2-1 | 3.00 | 0.95 |
| 2012-05-23 | Scott Diamond | L | 26 | L 0-6 | @ CHA | 4 | 11 | L | 6.0 | 9 | 5 | 2 | 1 | 1 | 4 | 94 | 33 | 61 | 65% | 3-1 | 1.80 | 1.16 |
| 2012-05-24 | Cole Devries | R | 27 | L 8-11 | @ CHA | 1 | 1 | L | 5.0 | 6 | 6 | 3 | 3 | 1 | 4 | 96 | 36 | 60 | 63% | 0-1 | 5.40 | 1.40 |
| 2012-05-25 | Anthony Swarzak | R | 27 | W 6-10 | vs DET | 4 | 27 | L | 3.2 | 9 | 6 | 6 | 0 | 1 | 3 | 60 | 19 | 41 | 68% | 0-4 | 5.75 | 1.33 |
| 2012-05-26 | Carl Pavano | R | 36 | W 3-6 | vs DET | 10 | 283 | L | 4.1 | 10 | 6 | 6 | 0 | 0 | 2 | 69 | 19 | 50 | 72% | 2-4 | 5.49 | 1.32 |
| 2012-05-27 | P.J. Walters | R | 27 | W 3-4 | vs DET | 4 | 8 | - | 6.0 | 7 | 2 | 2 | 0 | 5 | 4 | 92 | 43 | 49 | 53% | 2-1 | 3.00 | 1.19 |
| 2012-05-28 | Scott Diamond | L | 26 | L 5-4 | vs OAK | 5 | 12 | - | 6.1 | 9 | 3 | 3 | 2 | 1 | 4 | 98 | 36 | 62 | 63% | 3-1 | 2.25 | 1.22 |
| 2012-05-29 | Cole Devries | R | 27 | L 3-2 | vs OAK | 2 | 2 | - | 5.0 | 2 | 0 | 0 | 0 | 5 | 1 | 92 | 41 | 51 | 55% | 0-1 | 2.70 | 1.40 |
| 2012-05-30 | Francisco Liriano | L | 29 | L 4-0 | vs OAK | 7 | 120 | W | 6.0 | 3 | 0 | 0 | 0 | 2 | 9 | 87 | 37 | 50 | 57% | 1-5 | 7.20 | 1.88 |
| 2012-06-01 | Carl Pavano | R | 36 | L 1-7 | @ CLE | 11 | 284 | L | 3.2 | 9 | 7 | 6 | 2 | 1 | 2 | 75 | 25 | 50 | 67% | 2-5 | 6.00 | 1.40 |
| 2012-06-02 | P.J. Walters | R | 27 | W 7-4 | @ CLE | 5 | 9 | - | 4.1 | 8 | 4 | 4 | 0 | 3 | 2 | 101 | 38 | 63 | 62% | 2-1 | 3.66 | 1.34 |
| 2012-06-03 | Scott Diamond | L | 26 | W 6-3 | @ CLE | 6 | 13 | W | 7.0 | 7 | 3 | 0 | 0 | 0 | 2 | 93 | 32 | 61 | 66% | 4-1 | 1.85 | 1.18 |
| 2012-06-04 | Cole Devries | R | 27 | W 10-7 | @ KCA | 3 | 3 | W | 5.0 | 6 | 5 | 4 | 1 | 0 | 4 | 79 | 25 | 54 | 68% | 1-1 | 4.20 | 1.33 |
| 2012-06-05 | Francisco Liriano | L | 29 | L 0-1 | @ KCA | 8 | 121 | L | 6.0 | 4 | 1 | 1 | 0 | 1 | 8 | 97 | 37 | 60 | 62% | 1-6 | 6.46 | 1.74 |
| 2012-06-06 | Nick Blackburn | R | 30 | W 4-2 | @ KCA | 8 | 126 | W | 5.0 | 5 | 2 | 2 | 1 | 2 | 1 | 92 | 41 | 51 | 55% | 2-4 | 7.82 | 1.74 |
| 2012-06-08 | P.J. Walters | R | 27 | L 8-7 | vs CHN | 6 | 10 | - | 5.0 | 8 | 5 | 5 | 2 | 1 | 2 | 84 | 31 | 53 | 63% | 2-1 | 4.38 | 1.41 |
| 2012-06-09 | Scott Diamond | L | 26 | L 11-3 | vs CHN | 7 | 14 | W | 6.0 | 7 | 0 | 0 | 0 | 0 | 5 | 87 | 25 | 62 | 71% | 5-1 | 1.60 | 1.18 |
| 2012-06-10 | Francisco Liriano | L | 29 | W 2-8 | vs CHN | 9 | 122 | L | 5.2 | 4 | 4 | 4 | 0 | 3 | 6 | 89 | 35 | 54 | 61% | 1-7 | 6.40 | 1.67 |
| 2012-06-12 | Nick Blackburn | R | 30 | L 11-7 | vs PHI | 9 | 127 | W | 5.0 | 8 | 4 | 4 | 0 | 2 | 1 | 95 | 39 | 56 | 59% | 3-4 | 7.74 | 1.77 |
| 2012-06-13 | P.J. Walters | R | 27 | W 8-9 | vs PHI | 7 | 11 | L | 0.0 | 4 | 4 | 4 | 0 | 0 | 0 | 15 | 5 | 10 | 67% | 2-2 | 5.35 | 1.51 |
| 2012-06-14 | Scott Diamond | L | 26 | W 1-6 | vs PHI | 8 | 15 | L | 6.0 | 5 | 4 | 4 | 2 | 2 | 1 | 100 | 35 | 65 | 65% | 5-2 | 2.12 | 1.18 |
| 2012-06-15 | Francisco Liriano | L | 29 | W 3-5 | vs MIL | 10 | 123 | - | 6.0 | 1 | 3 | 3 | 1 | 4 | 6 | 100 | 40 | 60 | 60% | 1-7 | 6.21 | 1.59 |
| 2012-06-16 | Liam Hendriks | R | 23 | W 2-6 | vs MIL | 5 | 9 | L | 5.0 | 8 | 5 | 2 | 3 | 1 | 5 | 87 | 34 | 53 | 61% | 0-3 | 7.83 | 1.87 |
| 2012-06-17 | Nick Blackburn | R | 30 | L 5-4 | vs MIL | 10 | 128 | - | 6.0 | 9 | 4 | 4 | 1 | 2 | 3 | 100 | 39 | 61 | 61% | 3-4 | 7.53 | 1.78 |
| 2012-06-19 | Scott Diamond | L | 26 | L 2-7 | @ PIT | 9 | 16 | L | 5.1 | 8 | 4 | 4 | 1 | 2 | 1 | 101 | 44 | 57 | 56% | 5-3 | 2.57 | 1.25 |
| 2012-06-20 | Francisco Liriano | L | 29 | W 2-1 | @ PIT | 11 | 124 | - | 6.2 | 4 | 1 | 1 | 0 | 2 | 6 | 96 | 37 | 59 | 61% | 1-7 | 5.77 | 1.53 |
| 2012-06-21 | Liam Hendriks | R | 23 | L 1-9 | @ PIT | 6 | 10 | L | 5.0 | 8 | 6 | 3 | 1 | 0 | 3 | 93 | 35 | 58 | 62% | 0-4 | 7.39 | 1.82 |
| 2012-06-22 | Nick Blackburn | R | 30 | W 5-4 | @ CIN | 11 | 129 | W | 5.0 | 5 | 4 | 4 | 2 | 2 | 2 | 69 | 23 | 46 | 67% | 4-4 | 7.50 | 1.74 |
| 2012-06-23 | Brian Duensing | L | 29 | L 0-6 | @ CIN | 1 | 51 | L | 3.0 | 4 | 4 | 4 | 1 | 2 | 1 | 63 | 23 | 40 | 63% | 1-3 | 3.79 | 1.13 |
| 2012-06-24 | Scott Diamond | L | 26 | W 4-3 | @ CIN | 10 | 17 | W | 8.0 | 8 | 3 | 3 | 1 | 1 | 7 | 82 | 17 | 65 | 79% | 6-3 | 2.67 | 1.23 |
| 2012-06-25 | Francisco Liriano | L | 29 | L 4-1 | vs CHA | 12 | 125 | W | 7.0 | 4 | 1 | 1 | 0 | 2 | 5 | 104 | 45 | 59 | 57% | 2-7 | 5.32 | 1.46 |
| 2012-06-26 | Liam Hendriks | R | 23 | W 2-3 | vs CHA | 7 | 11 | L | 6.1 | 5 | 3 | 3 | 1 | 1 | 5 | 91 | 31 | 60 | 66% | 0-5 | 6.88 | 1.68 |
| 2012-06-27 | Nick Blackburn | R | 30 | W 5-12 | vs CHA | 12 | 130 | L | 5.0 | 9 | 6 | 6 | 2 | 0 | 3 | 70 | 20 | 50 | 71% | 4-5 | 7.78 | 1.75 |
| 2012-06-29 | Brian Duensing | L | 29 | W 3-4 | vs KCA | 2 | 52 | L | 4.0 | 8 | 3 | 3 | 1 | 0 | 1 | 66 | 21 | 45 | 68% | 1-4 | 4.07 | 1.21 |
| 2012-06-30 | Scott Diamond | L | 26 | L 7-2 | vs KCA | 11 | 18 | W | 8.0 | 6 | 2 | 2 | 0 | 2 | 4 | 101 | 36 | 65 | 64% | 7-3 | 2.63 | 1.21 |
| 2012-06-30 | Cole Devries | R | 27 | L 5-1 | vs KCA | 4 | 4 | W | 6.0 | 5 | 1 | 1 | 1 | 1 | 6 | 93 | 28 | 65 | 70% | 2-1 | 3.43 | 1.24 |
| 2012-07-01 | Francisco Liriano | L | 29 | L 10-8 | vs KCA | 13 | 126 | - | 5.1 | 5 | 5 | 4 | 0 | 4 | 6 | 107 | 44 | 63 | 59% | 2-7 | 5.38 | 1.47 |
| 2012-07-02 | Liam Hendriks | R | 23 | W 6-4 | @ DET | 8 | 12 | - | 4.0 | 6 | 4 | 4 | 0 | 4 | 1 | 80 | 37 | 43 | 54% | 0-5 | 7.11 | 1.76 |
| 2012-07-03 | Nick Blackburn | R | 30 | W 8-6 | @ DET | 13 | 131 | - | 4.0 | 8 | 6 | 6 | 2 | 1 | 1 | 75 | 27 | 48 | 64% | 4-5 | 8.14 | 1.78 |
| 2012-07-04 | Brian Duensing | L | 29 | L 1-5 | @ DET | 3 | 53 | L | 4.1 | 4 | 2 | 2 | 0 | 1 | 2 | 64 | 25 | 39 | 61% | 1-5 | 4.11 | 1.22 |
| 2012-07-05 | Scott Diamond | L | 26 | L 3-7 | @ DET | 12 | 19 | - | 7.0 | 5 | 2 | 2 | 0 | 1 | 4 | 90 | 31 | 59 | 66% | 7-3 | 2.62 | 1.18 |
| 2012-07-06 | Francisco Liriano | L | 29 | W 5-1 | @ TEX | 14 | 127 | W | 6.2 | 5 | 1 | 1 | 0 | 6 | 6 | 111 | 53 | 58 | 52% | 3-7 | 5.10 | 1.49 |
| 2012-07-07 | Samuel Deduno | R | 29 | L 3-4 | @ TEX | 1 | 1 | - | 5.1 | 6 | 3 | 3 | 2 | 3 | 3 | 86 | 39 | 47 | 55% | 0-0 | 5.40 | 1.80 |
| 2012-07-08 | Cole Devries | R | 27 | L 3-4 | @ TEX | 5 | 5 | - | 7.0 | 3 | 0 | 0 | 0 | 1 | 5 | 84 | 25 | 59 | 70% | 2-1 | 3.00 | 1.10 |
| 2012-07-13 | Francisco Liriano | L | 29 | W 3-6 | vs OAK | 15 | 128 | L | 8.0 | 4 | 4 | 3 | 1 | 1 | 15 | 112 | 37 | 75 | 67% | 3-8 | 4.95 | 1.42 |
| 2012-07-14 | Cole Devries | R | 27 | W 3-9 | vs OAK | 6 | 6 | L | 5.0 | 6 | 7 | 7 | 3 | 0 | 3 | 85 | 24 | 61 | 72% | 2-2 | 4.37 | 1.11 |
| 2012-07-15 | Brian Duensing | L | 29 | W 4-9 | vs OAK | 4 | 54 | L | 2.0 | 7 | 6 | 6 | 3 | 2 | 3 | 67 | 23 | 44 | 66% | 1-6 | 5.06 | 1.35 |
| 2012-07-16 | Scott Diamond | L | 26 | L 19-7 | vs BAL | 13 | 20 | W | 6.0 | 9 | 5 | 5 | 1 | 1 | 3 | 100 | 33 | 67 | 67% | 8-3 | 2.96 | 1.21 |
| 2012-07-17 | Samuel Deduno | R | 29 | L 6-4 | vs BAL | 2 | 2 | - | 4.1 | 6 | 4 | 3 | 1 | 5 | 5 | 98 | 42 | 56 | 57% | 0-0 | 5.40 | 2.00 |
| 2012-07-18 | Francisco Liriano | L | 29 | W 1-2 | vs BAL | 16 | 129 | L | 6.0 | 4 | 2 | 2 | 1 | 3 | 10 | 99 | 42 | 57 | 58% | 3-9 | 4.82 | 1.40 |
| 2012-07-19 | Cole Devries | R | 27 | W 3-4 | vs BAL | 7 | 7 | - | 6.0 | 5 | 1 | 1 | 1 | 1 | 5 | 94 | 38 | 56 | 60% | 2-2 | 3.95 | 1.10 |
| 2012-07-20 | Nick Blackburn | R | 30 | W 2-1 | @ KCA | 14 | 132 | - | 6.2 | 7 | 1 | 1 | 0 | 0 | 2 | 103 | 25 | 78 | 76% | 4-5 | 7.46 | 1.70 |
| 2012-07-21 | Scott Diamond | L | 26 | L 3-7 | @ KCA | 14 | 21 | L | 6.0 | 10 | 4 | 4 | 0 | 2 | 2 | 96 | 34 | 62 | 65% | 8-4 | 3.16 | 1.26 |
| 2012-07-22 | Samuel Deduno | R | 29 | W 7-5 | @ KCA | 3 | 3 | W | 6.1 | 6 | 1 | 1 | 0 | 3 | 4 | 105 | 31 | 74 | 70% | 1-0 | 3.94 | 1.81 |
| 2012-07-23 | Francisco Liriano | L | 29 | L 4-7 | @ CHA | 17 | 130 | L | 2.2 | 7 | 7 | 7 | 3 | 1 | 2 | 57 | 17 | 40 | 70% | 3-10 | 5.31 | 1.44 |
| 2012-07-24 | Cole Devries | R | 27 | L 4-11 | @ CHA | 8 | 8 | - | 6.0 | 7 | 2 | 1 | 1 | 0 | 4 | 94 | 37 | 57 | 61% | 2-2 | 3.64 | 1.11 |
| 2012-07-25 | Nick Blackburn | R | 30 | L 2-8 | @ CHA | 15 | 133 | L | 4.1 | 10 | 8 | 8 | 2 | 1 | 1 | 87 | 31 | 56 | 64% | 4-6 | 8.03 | 1.76 |
| 2012-07-27 | Scott Diamond | L | 26 | L 11-0 | vs CLE | 15 | 22 | W | 9.0 | 3 | 0 | 0 | 0 | 0 | 6 | 98 | 31 | 67 | 68% | 9-4 | 2.88 | 1.18 |
| 2012-07-28 | Samuel Deduno | R | 29 | L 12-5 | vs CLE | 4 | 4 | W | 7.0 | 2 | 1 | 1 | 0 | 5 | 6 | 105 | 43 | 62 | 59% | 2-0 | 3.13 | 1.57 |
| 2012-07-29 | Brian Duensing | L | 29 | L 5-1 | vs CLE | 5 | 55 | W | 6.0 | 5 | 1 | 1 | 0 | 0 | 2 | 69 | 21 | 48 | 70% | 2-6 | 4.50 | 1.32 |
| 2012-07-30 | Cole Devries | R | 27 | L 7-6 | vs CHA | 9 | 9 | - | 5.0 | 7 | 5 | 4 | 1 | 1 | 3 | 99 | 35 | 64 | 65% | 2-2 | 3.98 | 1.15 |
| 2012-07-31 | Nick Blackburn | R | 30 | W 3-4 | vs CHA | 16 | 134 | - | 8.0 | 5 | 2 | 2 | 0 | 1 | 2 | 106 | 33 | 73 | 69% | 4-6 | 7.46 | 1.66 |
| 2012-08-01 | Scott Diamond | L | 26 | W 2-3 | vs CHA | 16 | 23 | L | 7.1 | 8 | 3 | 3 | 0 | 0 | 3 | 93 | 30 | 63 | 68% | 9-5 | 2.94 | 1.18 |
| 2012-08-02 | Samuel Deduno | R | 29 | W 5-0 | @ BOS | 5 | 5 | W | 6.0 | 2 | 0 | 0 | 0 | 4 | 1 | 101 | 51 | 50 | 50% | 3-0 | 2.48 | 1.45 |
| 2012-08-03 | Brian Duensing | L | 29 | W 6-5 | @ BOS | 6 | 56 | - | 6.0 | 10 | 5 | 2 | 1 | 0 | 3 | 93 | 32 | 61 | 66% | 2-6 | 4.36 | 1.35 |
| 2012-08-04 | Cole Devries | R | 27 | W 6-4 | @ BOS | 10 | 10 | - | 7.0 | 4 | 2 | 2 | 1 | 2 | 5 | 109 | 37 | 72 | 66% | 2-2 | 3.81 | 1.12 |
| 2012-08-05 | Nick Blackburn | R | 30 | L 4-6 | @ BOS | 17 | 135 | L | 5.0 | 9 | 4 | 4 | 1 | 0 | 4 | 97 | 30 | 67 | 69% | 4-7 | 7.45 | 1.67 |
| 2012-08-06 | Scott Diamond | L | 26 | W 14-3 | @ CLE | 17 | 24 | W | 7.0 | 7 | 3 | 2 | 1 | 1 | 3 | 105 | 45 | 60 | 57% | 10-5 | 2.92 | 1.18 |
| 2012-08-07 | Samuel Deduno | R | 29 | W 7-5 | @ CLE | 6 | 6 | - | 4.0 | 5 | 4 | 4 | 1 | 5 | 3 | 90 | 38 | 52 | 58% | 3-0 | 3.27 | 1.58 |
| 2012-08-08 | Brian Duensing | L | 29 | L 2-6 | @ CLE | 7 | 57 | L | 7.0 | 11 | 6 | 4 | 0 | 1 | 3 | 107 | 34 | 73 | 68% | 2-7 | 4.44 | 1.38 |
| 2012-08-10 | Cole Devries | R | 27 | W 6-12 | vs TBA | 11 | 11 | L | 1.1 | 7 | 8 | 7 | 1 | 0 | 1 | 40 | 14 | 26 | 65% | 2-3 | 4.80 | 1.22 |
| 2012-08-11 | Nick Blackburn | R | 30 | W 2-4 | vs TBA | 18 | 136 | L | 6.0 | 11 | 4 | 4 | 3 | 1 | 2 | 91 | 30 | 61 | 67% | 4-8 | 7.35 | 1.69 |
| 2012-08-12 | Scott Diamond | L | 26 | W 3-7 | vs TBA | 18 | 25 | - | 7.0 | 8 | 3 | 3 | 2 | 2 | 6 | 95 | 31 | 64 | 67% | 10-5 | 2.98 | 1.19 |
| 2012-08-13 | Samuel Deduno | R | 29 | L 9-3 | vs DET | 7 | 7 | W | 7.0 | 5 | 3 | 3 | 0 | 5 | 6 | 102 | 45 | 57 | 56% | 4-0 | 3.38 | 1.55 |
| 2012-08-14 | Brian Duensing | L | 29 | W 4-8 | vs DET | 8 | 58 | L | 6.0 | 8 | 5 | 5 | 1 | 2 | 4 | 88 | 31 | 57 | 65% | 2-8 | 4.67 | 1.41 |
| 2012-08-15 | Cole Devries | R | 28 | W 1-5 | vs DET | 12 | 12 | L | 4.0 | 8 | 4 | 4 | 2 | 2 | 3 | 83 | 34 | 49 | 59% | 2-4 | 5.06 | 1.30 |
| 2012-08-17 | Nick Blackburn | R | 30 | L 3-5 | @ SEA | 19 | 137 | L | 5.1 | 11 | 5 | 5 | 2 | 1 | 1 | 86 | 30 | 56 | 65% | 4-9 | 7.36 | 1.71 |
| 2012-08-18 | Scott Diamond | L | 26 | L 2-3 | @ SEA | 19 | 26 | - | 6.2 | 9 | 2 | 2 | 1 | 0 | 2 | 100 | 36 | 64 | 64% | 10-5 | 2.95 | 1.20 |
| 2012-08-19 | Samuel Deduno | R | 29 | L 1-5 | @ SEA | 8 | 8 | L | 6.0 | 5 | 2 | 2 | 0 | 6 | 2 | 104 | 46 | 58 | 56% | 4-1 | 3.33 | 1.59 |
| 2012-08-20 | Brian Duensing | L | 29 | W 7-2 | @ OAK | 9 | 59 | W | 6.0 | 5 | 2 | 1 | 0 | 1 | 7 | 106 | 40 | 66 | 62% | 3-8 | 4.45 | 1.38 |
| 2012-08-21 | Cole Devries | R | 28 | L 1-4 | @ OAK | 13 | 13 | L | 5.2 | 6 | 2 | 2 | 0 | 3 | 3 | 111 | 44 | 67 | 60% | 2-5 | 4.89 | 1.31 |
| 2012-08-22 | Liam Hendriks | R | 24 | L 1-5 | @ OAK | 9 | 13 | L | 5.0 | 6 | 4 | 4 | 0 | 3 | 2 | 101 | 42 | 59 | 58% | 0-6 | 7.12 | 1.77 |
| 2012-08-23 | Scott Diamond | L | 26 | L 6-10 | @ TEX | 20 | 27 | - | 2.1 | 3 | 2 | 2 | 0 | 2 | 1 | 53 | 23 | 30 | 57% | 10-5 | 3.05 | 1.22 |
| 2012-08-24 | Samuel Deduno | R | 29 | L 0-8 | @ TEX | 9 | 9 | L | 5.0 | 11 | 7 | 7 | 1 | 1 | 0 | 85 | 33 | 52 | 61% | 4-2 | 4.24 | 1.67 |
| 2012-08-25 | Brian Duensing | L | 30 | L 3-9 | @ TEX | 10 | 60 | L | 2.1 | 10 | 9 | 9 | 2 | 1 | 3 | 76 | 32 | 44 | 58% | 3-9 | 5.28 | 1.47 |
| 2012-08-26 | Cole Devries | R | 28 | W 6-5 | @ TEX | 14 | 14 | W | 5.0 | 3 | 2 | 1 | 0 | 0 | 5 | 102 | 33 | 69 | 68% | 3-5 | 4.68 | 1.27 |
| 2012-08-27 | Liam Hendriks | R | 24 | W 0-1 | vs SEA | 10 | 14 | L | 9.0 | 3 | 1 | 1 | 1 | 3 | 6 | 103 | 38 | 65 | 63% | 0-7 | 6.06 | 1.58 |
| 2012-08-28 | Scott Diamond | L | 26 | W 2-5 | vs SEA | 21 | 28 | L | 7.0 | 7 | 5 | 5 | 1 | 1 | 2 | 96 | 23 | 73 | 76% | 10-6 | 3.22 | 1.21 |
| 2012-08-29 | Samuel Deduno | R | 29 | L 10-0 | vs SEA | 10 | 10 | W | 7.0 | 2 | 0 | 0 | 0 | 0 | 9 | 98 | 30 | 68 | 69% | 5-2 | 3.72 | 1.50 |
| 2012-08-30 | Brian Duensing | L | 30 | W 4-5 | vs SEA | 11 | 61 | L | 5.1 | 4 | 4 | 3 | 0 | 2 | 3 | 70 | 28 | 42 | 60% | 3-10 | 5.28 | 1.46 |
| 2012-09-01 | Cole Devries | R | 28 | W 3-1 | @ KCA | 15 | 15 | W | 6.2 | 7 | 1 | 1 | 0 | 0 | 3 | 94 | 36 | 58 | 62% | 4-5 | 4.39 | 1.24 |
| 2012-09-01 | Liam Hendriks | R | 24 | W 8-7 | @ KCA | 11 | 15 | - | 3.2 | 10 | 5 | 3 | 0 | 0 | 5 | 81 | 27 | 54 | 67% | 0-7 | 6.11 | 1.64 |
| 2012-09-02 | Esmerling Vasquez | R | 29 | L 4-6 | @ KCA | 1 | 1 | L | 5.2 | 7 | 5 | 5 | 0 | 3 | 2 | 79 | 27 | 52 | 66% | 0-1 | 7.50 | 1.67 |
| 2012-09-03 | Samuel Deduno | R | 29 | L 2-4 | @ CHA | 11 | 11 | L | 6.0 | 6 | 2 | 2 | 1 | 3 | 3 | 98 | 42 | 56 | 57% | 5-3 | 3.66 | 1.50 |
| 2012-09-04 | Scott Diamond | L | 26 | W 18-9 | @ CHA | 22 | 29 | W | 5.0 | 7 | 4 | 4 | 0 | 2 | 4 | 89 | 32 | 57 | 64% | 11-6 | 3.36 | 1.23 |
| 2012-09-05 | P.J. Walters | R | 27 | L 2-6 | @ CHA | 8 | 12 | L | 5.0 | 5 | 6 | 6 | 2 | 3 | 4 | 101 | 43 | 58 | 57% | 2-3 | 6.00 | 1.52 |
| 2012-09-07 | Liam Hendriks | R | 24 | W 6-7 | vs CLE | 12 | 16 | - | 5.0 | 8 | 4 | 4 | 1 | 3 | 2 | 108 | 43 | 65 | 60% | 0-7 | 6.20 | 1.69 |
| 2012-09-08 | Cole Devries | R | 28 | L 3-0 | vs CLE | 16 | 16 | W | 6.0 | 3 | 0 | 0 | 0 | 1 | 2 | 84 | 37 | 47 | 56% | 5-5 | 4.09 | 1.20 |
| 2012-09-09 | Esmerling Vasquez | R | 29 | L 8-7 | vs CLE | 2 | 2 | - | 3.0 | 3 | 4 | 4 | 1 | 5 | 2 | 67 | 36 | 31 | 46% | 0-1 | 9.00 | 2.00 |
| 2012-09-10 | Samuel Deduno | R | 29 | L 7-2 | vs CLE | 12 | 12 | W | 7.0 | 3 | 2 | 2 | 1 | 3 | 6 | 108 | 36 | 72 | 67% | 6-3 | 3.55 | 1.44 |
| 2012-09-11 | Scott Diamond | L | 26 | W 1-9 | vs KCA | 23 | 30 | L | 6.0 | 10 | 4 | 4 | 0 | 3 | 2 | 98 | 35 | 63 | 64% | 11-7 | 3.47 | 1.27 |
| 2012-09-12 | P.J. Walters | R | 28 | W 5-10 | vs KCA | 9 | 13 | L | 4.0 | 7 | 6 | 6 | 1 | 2 | 3 | 71 | 27 | 44 | 62% | 2-4 | 6.65 | 1.59 |
| 2012-09-13 | Liam Hendriks | R | 24 | L 4-3 | vs KCA | 13 | 17 | - | 5.0 | 7 | 3 | 3 | 0 | 2 | 3 | 98 | 34 | 64 | 65% | 0-7 | 6.14 | 1.70 |
| 2012-09-14 | Esmerling Vasquez | R | 29 | W 0-6 | vs CHA | 3 | 3 | L | 5.2 | 3 | 3 | 3 | 0 | 4 | 4 | 112 | 43 | 69 | 62% | 0-2 | 7.71 | 1.79 |
| 2012-09-15 | Samuel Deduno | R | 29 | W 3-5 | vs CHA | 13 | 13 | L | 4.0 | 3 | 4 | 4 | 1 | 5 | 6 | 84 | 46 | 38 | 45% | 6-4 | 3.84 | 1.47 |
| 2012-09-16 | Scott Diamond | L | 26 | W 2-9 | vs CHA | 24 | 31 | L | 5.1 | 7 | 6 | 6 | 2 | 1 | 2 | 92 | 33 | 59 | 64% | 11-8 | 3.68 | 1.27 |
| 2012-09-18 | P.J. Walters | R | 28 | W 6-5 | @ CLE | 10 | 14 | - | 5.0 | 8 | 4 | 2 | 1 | 1 | 3 | 89 | 37 | 52 | 58% | 2-4 | 6.35 | 1.61 |
| 2012-09-19 | Liam Hendriks | R | 24 | W 6-4 | @ CLE | 14 | 18 | W | 6.0 | 2 | 2 | 2 | 1 | 2 | 2 | 101 | 41 | 60 | 59% | 1-7 | 5.88 | 1.61 |
| 2012-09-20 | Esmerling Vasquez | R | 29 | L 3-4 | @ CLE | 4 | 4 | - | 5.2 | 6 | 3 | 3 | 0 | 3 | 0 | 91 | 37 | 54 | 59% | 0-2 | 6.75 | 1.70 |
| 2012-09-22 | Samuel Deduno | R | 29 | L 0-8 | @ DET | 14 | 14 | L | 2.1 | 7 | 7 | 7 | 2 | 3 | 1 | 58 | 24 | 34 | 59% | 6-5 | 4.56 | 1.56 |
| 2012-09-23 | Scott Diamond | L | 26 | W 10-4 | @ DET | 25 | 32 | W | 7.0 | 4 | 2 | 2 | 0 | 3 | 5 | 103 | 43 | 60 | 58% | 12-8 | 3.63 | 1.26 |
| 2012-09-23 | P.J. Walters | R | 28 | W 2-1 | @ DET | 11 | 15 | - | 6.0 | 5 | 1 | 1 | 0 | 1 | 4 | 90 | 37 | 53 | 59% | 2-4 | 5.84 | 1.54 |
| 2012-09-24 | Liam Hendriks | R | 24 | W 3-6 | vs NYA | 15 | 19 | L | 6.1 | 8 | 6 | 6 | 4 | 1 | 4 | 92 | 27 | 65 | 71% | 1-8 | 6.12 | 1.60 |
| 2012-09-25 | Esmerling Vasquez | R | 29 | L 5-4 | vs NYA | 5 | 5 | - | 6.0 | 7 | 2 | 2 | 1 | 1 | 5 | 101 | 39 | 62 | 61% | 0-2 | 5.88 | 1.62 |
| 2012-09-26 | Samuel Deduno | R | 29 | W 2-8 | vs NYA | 15 | 15 | - | 1.2 | 0 | 0 | 0 | 0 | 2 | 2 | 30 | 15 | 15 | 50% | 6-5 | 4.44 | 1.54 |
| 2012-09-28 | Scott Diamond | L | 26 | L 4-2 | vs DET | 26 | 33 | - | 7.1 | 6 | 2 | 1 | 1 | 0 | 1 | 86 | 28 | 58 | 67% | 12-8 | 3.54 | 1.24 |
| 2012-09-29 | P.J. Walters | R | 28 | W 4-6 | vs DET | 12 | 16 | L | 5.0 | 4 | 2 | 2 | 1 | 1 | 5 | 92 | 32 | 60 | 65% | 2-5 | 5.66 | 1.50 |
| 2012-09-30 | Liam Hendriks | R | 24 | W 1-2 | vs DET | 16 | 20 | - | 7.0 | 5 | 0 | 0 | 0 | 2 | 3 | 99 | 31 | 68 | 69% | 1-8 | 5.61 | 1.55 |
| 2012-10-01 | Esmerling Vasquez | R | 29 | L 5-6 | @ TOR | 6 | 6 | - | 5.2 | 6 | 3 | 3 | 0 | 3 | 1 | 93 | 38 | 55 | 59% | 0-2 | 5.63 | 1.59 |
| 2012-10-02 | Anthony Swarzak | R | 27 | L 3-4 | @ TOR | 5 | 28 | L | 5.0 | 5 | 4 | 4 | 1 | 3 | 2 | 69 | 29 | 40 | 58% | 3-6 | 5.01 | 1.41 |
| 2012-10-03 | Scott Diamond | L | 26 | L 1-2 | @ TOR | 27 | 34 | L | 5.0 | 5 | 2 | 2 | 0 | 1 | 3 | 87 | 33 | 54 | 62% | 12-9 | 3.54 | 1.24 |