| 58 | Scott Diamond | - | 23 | 27 | 27 | 173.0 | 3.54 | 1.24 | 9.57 | 0.88 | 1.61 | 4.68 | 0.34 | 1.18 | 16 | 4 | 671 | .274 | 714 | 3.54 | 35.1 | 64.9 | 7.0 |
| 52 | Brian Duensing | - | 73 | 55 | 11 | 109.0 | 5.12 | 1.40 | 10.40 | 0.83 | 2.23 | 5.70 | 0.39 | 0.91 | 3 | 2 | 438 | .288 | 472 | 3.65 | 36.0 | 64.0 | 8.1 |
| 47 | Francisco Liriano | - | 62 | 22 | 17 | 100.0 | 5.31 | 1.44 | 8.01 | 1.08 | 4.95 | 9.81 | 0.50 | 0.90 | 8 | 4 | 372 | .239 | 440 | 3.89 | 41.2 | 58.8 | 13.6 |
| 53 | Nick Blackburn | - | - | 19 | 19 | 98.2 | 7.39 | 1.71 | 13.04 | 2.10 | 2.37 | 3.83 | 0.62 | 0.87 | 3 | 1 | 421 | .340 | 456 | 3.57 | 36.1 | 63.9 | 5.3 |
| 51 | Anthony Swarzak | - | - | 44 | 5 | 96.2 | 5.03 | 1.42 | 9.87 | 1.40 | 2.89 | 5.77 | 0.50 | 0.80 | 0 | 0 | 373 | .284 | 413 | 3.53 | 36.5 | 63.5 | 7.7 |
| 38 | Cole Devries | - | - | 17 | 16 | 87.2 | 4.11 | 1.21 | 9.03 | 1.64 | 1.85 | 5.95 | 0.31 | 0.50 | 7 | 4 | 349 | .252 | 375 | 3.91 | 36.3 | 63.7 | 7.7 |
| 62 | Liam Hendriks | - | - | 16 | 16 | 85.1 | 5.59 | 1.55 | 11.18 | 1.79 | 2.74 | 5.27 | 0.52 | 0.73 | 5 | 4 | 347 | .305 | 381 | 3.86 | 37.6 | 62.4 | 5.1 |
| 21 | Samuel Deduno | - | - | 15 | 15 | 79.0 | 4.44 | 1.54 | 7.86 | 1.14 | 6.04 | 6.49 | 0.93 | 1.47 | 8 | 5 | 286 | .241 | 347 | 3.90 | 41.5 | 58.5 | 7.7 |
| 31 | Alex Burnett | - | - | 67 | 0 | 71.2 | 3.52 | 1.35 | 8.92 | 0.50 | 3.27 | 4.52 | 0.72 | 1.14 | 0 | 3 | 276 | .257 | 309 | 3.74 | 35.7 | 64.3 | 7.1 |
| 15 | Glen Perkins | - | 51 | 70 | 0 | 70.1 | 2.56 | 1.04 | 7.29 | 1.02 | 2.05 | 9.98 | 0.21 | 0.79 | 0 | 3 | 257 | .222 | 281 | 3.81 | 30.9 | 69.1 | 14.1 |
| 48 | Carl Pavano | - | - | 11 | 11 | 63.0 | 6.00 | 1.40 | 11.43 | 1.29 | 1.14 | 4.71 | 0.24 | 0.74 | 4 | 2 | 256 | .312 | 268 | 3.43 | 34.0 | 66.0 | 6.7 |
| 61 | Jared Burton | - | - | 64 | 0 | 62.0 | 2.18 | 0.92 | 5.95 | 0.73 | 2.32 | 7.98 | 0.29 | 0.93 | 0 | 5 | 221 | .186 | 245 | 3.84 | 33.9 | 66.1 | 13.9 |
| 39 | P.J. Walters | - | - | 12 | 12 | 61.2 | 5.69 | 1.51 | 10.36 | 1.75 | 3.21 | 6.13 | 0.52 | 0.74 | 5 | 3 | 244 | .291 | 271 | 3.78 | 39.3 | 60.7 | 6.4 |
| 60 | Jeff Gray | - | - | 49 | 0 | 52.0 | 5.71 | 1.54 | 10.04 | 1.56 | 3.81 | 4.50 | 0.85 | 0.74 | 0 | 4 | 209 | .278 | 236 | 3.64 | 35.4 | 64.6 | 8.1 |
| 50 | Casey Fien | - | - | 35 | 0 | 35.0 | 2.06 | 0.97 | 6.43 | 0.77 | 2.31 | 8.23 | 0.28 | 0.36 | 0 | 1 | 128 | .195 | 141 | 4.19 | 35.7 | 64.3 | 9.5 |
| 21 | Jason Marquis | - | - | 7 | 7 | 34.0 | 8.47 | 1.94 | 13.76 | 2.38 | 3.71 | 3.18 | 1.17 | 1.22 | 0 | 0 | 0 | -- | 0 | -- | 41.9 | 58.1 | 3.7 |
| 59 | Esmerling Vasquez | - | - | 6 | 6 | 31.2 | 5.68 | 1.61 | 9.09 | 0.57 | 5.40 | 3.98 | 1.36 | 0.51 | 1 | 1 | 117 | .274 | 141 | 3.85 | 40.5 | 59.5 | 8.5 |
| 55 | Matt Capps | - | 71 | 30 | 0 | 29.1 | 3.68 | 1.09 | 8.59 | 1.53 | 1.23 | 5.52 | 0.22 | 0.81 | 0 | 0 | 116 | .241 | 120 | 3.69 | 33.9 | 66.1 | 8.4 |
| 64 | Tyler Robertson | - | - | 40 | 0 | 25.0 | 5.40 | 1.40 | 7.56 | 1.44 | 5.04 | 9.36 | 0.54 | 1.19 | 0 | 1 | 94 | .223 | 111 | 3.95 | 40.5 | 59.5 | 14.1 |
| 49 | Jeff Manship | - | - | 12 | 0 | 21.2 | 7.89 | 1.66 | 12.05 | 1.66 | 2.91 | 4.98 | 0.58 | 1.00 | 0 | 1 | 89 | .326 | 98 | 3.94 | 38.1 | 61.9 | 8.3 |
| 57 | Kyle Waldrop | - | - | 17 | 0 | 21.1 | 2.53 | 1.55 | 11.39 | 0.84 | 2.53 | 2.95 | 0.86 | 2.71 | 0 | 3 | 85 | .318 | 94 | 3.67 | 37.7 | 62.3 | 6.7 |
| 67 | Luis Perdomo | - | - | 15 | 0 | 17.0 | 3.18 | 1.59 | 7.94 | -- | 6.35 | 4.24 | 1.50 | 0.97 | 0 | 2 | 63 | .238 | 78 | 4.04 | 44.4 | 55.6 | 6.0 |
| 44 | Matt Maloney | - | - | 9 | 0 | 11.0 | 8.18 | 1.64 | 13.91 | 1.64 | 0.82 | 4.09 | 0.20 | 0.73 | 0 | 1 | 49 | .347 | 52 | 2.83 | 31.3 | 68.7 | 10.2 |
| 17 | Lester Oliveros | - | - | 1 | 0 | 1.2 | 5.40 | 1.20 | 5.40 | -- | 5.40 | 5.40 | 1.00 | 0.25 | 0 | 0 | 6 | .167 | 7 | 4.57 | 40.6 | 59.4 | 3.1 |
| 41 | Drew Butera | - | - | 1 | 0 | 1.0 | 0.00 | 1.00 | 0.00 | -- | 9.00 | 9.00 | 1.00 | -- | 0 | 0 | 3 | .000 | 4 | 4.50 | 50.0 | 50.0 | 5.6 |