| Central | W | L | Pct | GB |
| Milwaukee | 96 | 66 | .593 | -- |
| St. Louis | 90 | 72 | .556 | 6.0 |
| Cincinnati | 79 | 83 | .488 | 17.0 |
| Pittsburgh | 72 | 90 | .444 | 24.0 |
| Chi Cubs | 71 | 91 | .438 | 25.0 |
| Houston | 56 | 106 | .346 | 40.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2011-03-31 | Edinson Volquez | R | 28 | L 7-6 | vs MIL | 1 | 71 | - | 6.0 | 7 | 5 | 5 | 3 | 2 | 5 | 91 | 28 | 63 | 69% | 0-0 | 7.50 | 1.50 |
| 2011-04-02 | Travis Wood | L | 24 | L 4-2 | vs MIL | 1 | 18 | W | 7.0 | 4 | 1 | 1 | 1 | 0 | 7 | 83 | 17 | 66 | 80% | 1-0 | 1.29 | 0.57 |
| 2011-04-03 | Bronson Arroyo | R | 34 | L 12-3 | vs MIL | 1 | 260 | W | 7.0 | 6 | 3 | 3 | 2 | 0 | 5 | 86 | 22 | 64 | 74% | 1-0 | 3.86 | 0.86 |
| 2011-04-05 | Mike Leake | R | 23 | L 8-2 | vs HOU | 1 | 23 | W | 6.0 | 3 | 2 | 2 | 0 | 2 | 4 | 94 | 35 | 59 | 63% | 1-0 | 3.00 | 0.83 |
| 2011-04-06 | Edinson Volquez | R | 28 | L 12-4 | vs HOU | 2 | 72 | W | 5.0 | 5 | 4 | 4 | 0 | 5 | 8 | 99 | 41 | 58 | 59% | 1-0 | 7.36 | 1.73 |
| 2011-04-07 | Sam LeCure | R | 27 | W 2-3 | vs HOU | 1 | 7 | - | 5.0 | 3 | 2 | 2 | 0 | 2 | 6 | 82 | 33 | 49 | 60% | 0-0 | 3.00 | 0.83 |
| 2011-04-08 | Travis Wood | L | 24 | L 2-13 | @ ARI | 2 | 19 | L | 5.0 | 7 | 6 | 6 | 0 | 2 | 4 | 79 | 29 | 50 | 63% | 1-1 | 5.25 | 1.08 |
| 2011-04-09 | Bronson Arroyo | R | 34 | W 6-1 | @ ARI | 2 | 261 | W | 6.0 | 8 | 1 | 0 | 0 | 0 | 6 | 95 | 34 | 61 | 64% | 2-0 | 2.08 | 1.08 |
| 2011-04-10 | Mike Leake | R | 23 | L 8-10 | @ ARI | 2 | 24 | - | 4.2 | 9 | 6 | 6 | 1 | 2 | 4 | 85 | 31 | 54 | 64% | 1-0 | 6.55 | 1.45 |
| 2011-04-11 | Edinson Volquez | R | 28 | W 3-2 | @ SDN | 3 | 73 | W | 6.0 | 3 | 2 | 2 | 0 | 3 | 5 | 93 | 39 | 54 | 58% | 2-0 | 5.82 | 1.47 |
| 2011-04-12 | Sam LeCure | R | 27 | W 8-2 | @ SDN | 2 | 8 | - | 6.0 | 1 | 1 | 1 | 0 | 2 | 8 | 86 | 33 | 53 | 62% | 0-0 | 2.25 | 0.67 |
| 2011-04-13 | Travis Wood | L | 24 | L 2-3 | @ SDN | 3 | 20 | - | 6.2 | 5 | 1 | 1 | 0 | 3 | 5 | 98 | 44 | 54 | 55% | 1-1 | 3.79 | 1.11 |
| 2011-04-15 | Bronson Arroyo | R | 34 | W 1-6 | vs PIT | 3 | 262 | L | 4.0 | 9 | 5 | 5 | 2 | 2 | 4 | 90 | 30 | 60 | 67% | 2-1 | 4.24 | 1.47 |
| 2011-04-16 | Mike Leake | R | 23 | L 11-2 | vs PIT | 3 | 25 | W | 6.0 | 4 | 2 | 2 | 0 | 4 | 6 | 102 | 45 | 57 | 56% | 2-0 | 5.29 | 1.41 |
| 2011-04-17 | Edinson Volquez | R | 28 | W 6-7 | vs PIT | 4 | 74 | - | 5.2 | 5 | 6 | 6 | 3 | 6 | 6 | 108 | 48 | 60 | 56% | 2-0 | 6.65 | 1.57 |
| 2011-04-18 | Travis Wood | L | 24 | W 3-9 | vs PIT | 4 | 21 | L | 3.1 | 8 | 6 | 6 | 0 | 1 | 3 | 83 | 27 | 56 | 67% | 1-2 | 5.73 | 1.36 |
| 2011-04-19 | Sam LeCure | R | 27 | W 4-5 | vs ARI | 3 | 9 | L | 5.1 | 9 | 5 | 5 | 4 | 0 | 3 | 88 | 36 | 52 | 59% | 0-1 | 4.24 | 1.00 |
| 2011-04-20 | Bronson Arroyo | R | 34 | W 1-3 | vs ARI | 4 | 263 | L | 6.1 | 5 | 3 | 3 | 0 | 1 | 8 | 108 | 40 | 68 | 63% | 2-2 | 4.30 | 1.35 |
| 2011-04-21 | Mike Leake | R | 23 | L 7-4 | vs ARI | 4 | 26 | W | 7.0 | 4 | 3 | 3 | 1 | 2 | 6 | 96 | 35 | 61 | 64% | 3-0 | 4.88 | 1.25 |
| 2011-04-22 | Matt Maloney | L | 27 | L 2-4 | @ SLN | 1 | 10 | L | 2.0 | 8 | 3 | 3 | 0 | 1 | 1 | 72 | 28 | 44 | 61% | 0-1 | 8.25 | 2.00 |
| 2011-04-23 | Travis Wood | L | 24 | W 5-3 | @ SLN | 5 | 22 | - | 6.1 | 8 | 3 | 3 | 1 | 1 | 5 | 93 | 37 | 56 | 60% | 1-2 | 5.46 | 1.39 |
| 2011-04-24 | Edinson Volquez | R | 28 | L 0-3 | @ SLN | 5 | 75 | L | 5.2 | 6 | 3 | 3 | 1 | 3 | 7 | 109 | 45 | 64 | 59% | 2-1 | 6.43 | 1.61 |
| 2011-04-25 | Bronson Arroyo | R | 34 | W 9-5 | @ MIL | 5 | 264 | W | 6.1 | 6 | 2 | 1 | 0 | 2 | 4 | 103 | 39 | 64 | 62% | 3-2 | 3.60 | 1.30 |
| 2011-04-26 | Mike Leake | R | 23 | L 2-3 | @ MIL | 5 | 27 | - | 7.0 | 7 | 2 | 2 | 2 | 0 | 6 | 101 | 40 | 61 | 60% | 3-0 | 4.35 | 1.19 |
| 2011-04-27 | Sam LeCure | R | 27 | W 7-6 | @ MIL | 4 | 10 | - | 4.1 | 6 | 4 | 3 | 0 | 1 | 2 | 73 | 24 | 49 | 67% | 0-1 | 4.50 | 1.09 |
| 2011-04-29 | Travis Wood | L | 24 | W 6-7 | vs FLO | 6 | 23 | L | 3.1 | 8 | 7 | 7 | 1 | 2 | 3 | 91 | 34 | 57 | 63% | 1-3 | 6.75 | 1.53 |
| 2011-04-30 | Edinson Volquez | R | 28 | L 4-3 | vs FLO | 6 | 76 | - | 5.0 | 2 | 1 | 1 | 0 | 5 | 4 | 101 | 44 | 57 | 56% | 2-1 | 5.73 | 1.58 |
| 2011-05-01 | Bronson Arroyo | R | 34 | W 5-9 | vs FLO | 6 | 265 | L | 7.0 | 7 | 5 | 5 | 3 | 2 | 3 | 99 | 33 | 66 | 67% | 3-3 | 4.14 | 1.30 |
| 2011-05-03 | Mike Leake | R | 23 | W 4-10 | vs HOU | 6 | 28 | L | 3.2 | 7 | 7 | 7 | 1 | 1 | 5 | 71 | 24 | 47 | 66% | 3-1 | 5.82 | 1.32 |
| 2011-05-04 | Travis Wood | L | 24 | L 3-2 | vs HOU | 7 | 24 | - | 6.0 | 5 | 2 | 2 | 0 | 4 | 7 | 104 | 39 | 65 | 63% | 1-3 | 6.16 | 1.53 |
| 2011-05-05 | Homer Bailey | R | 25 | L 10-4 | vs HOU | 1 | 57 | W | 6.0 | 4 | 1 | 1 | 0 | 1 | 7 | 95 | 33 | 62 | 65% | 1-0 | 1.50 | 0.83 |
| 2011-05-06 | Edinson Volquez | R | 28 | W 5-4 | @ CHN | 7 | 77 | W | 5.0 | 6 | 4 | 3 | 0 | 4 | 3 | 108 | 47 | 61 | 56% | 3-1 | 5.68 | 1.63 |
| 2011-05-07 | Bronson Arroyo | R | 34 | L 2-3 | @ CHN | 7 | 266 | - | 7.1 | 7 | 1 | 1 | 1 | 2 | 3 | 95 | 26 | 69 | 73% | 3-3 | 3.68 | 1.30 |
| 2011-05-08 | Johnny Cueto | R | 25 | W 2-0 | @ CHN | 1 | 93 | W | 6.0 | 5 | 0 | 0 | 0 | 1 | 4 | 105 | 40 | 65 | 62% | 1-0 | 0.00 | 1.00 |
| 2011-05-09 | Travis Wood | L | 24 | W 6-1 | @ HOU | 8 | 25 | W | 6.2 | 6 | 0 | 0 | 0 | 1 | 6 | 106 | 35 | 71 | 67% | 2-3 | 5.32 | 1.48 |
| 2011-05-10 | Homer Bailey | R | 25 | W 7-3 | @ HOU | 2 | 58 | W | 7.0 | 5 | 0 | 0 | 0 | 0 | 5 | 93 | 32 | 61 | 66% | 2-0 | 0.69 | 0.77 |
| 2011-05-11 | Edinson Volquez | R | 28 | L 3-4 | @ HOU | 8 | 78 | - | 4.0 | 3 | 3 | 3 | 0 | 5 | 3 | 87 | 41 | 46 | 53% | 3-1 | 5.79 | 1.67 |
| 2011-05-13 | Bronson Arroyo | R | 34 | L 6-5 | vs SLN | 8 | 267 | - | 6.0 | 6 | 4 | 3 | 0 | 3 | 3 | 102 | 38 | 64 | 63% | 3-3 | 3.78 | 1.32 |
| 2011-05-14 | Johnny Cueto | R | 25 | L 7-3 | vs SLN | 2 | 94 | W | 7.2 | 3 | 3 | 0 | 1 | 2 | 5 | 100 | 38 | 62 | 62% | 2-0 | 0.00 | 0.79 |
| 2011-05-15 | Travis Wood | L | 24 | L 9-7 | vs SLN | 9 | 26 | W | 6.0 | 7 | 2 | 2 | 2 | 1 | 3 | 103 | 39 | 64 | 62% | 3-3 | 5.04 | 1.46 |
| 2011-05-16 | Homer Bailey | R | 25 | L 7-4 | vs CHN | 3 | 59 | W | 6.0 | 6 | 4 | 3 | 1 | 3 | 4 | 106 | 40 | 66 | 62% | 3-0 | 1.89 | 1.00 |
| 2011-05-17 | Edinson Volquez | R | 28 | L 7-5 | vs CHN | 9 | 79 | - | 6.0 | 3 | 3 | 3 | 1 | 1 | 9 | 97 | 33 | 64 | 66% | 3-1 | 5.63 | 1.54 |
| 2011-05-18 | Bronson Arroyo | R | 34 | W 0-5 | vs PIT | 9 | 268 | L | 7.0 | 7 | 5 | 5 | 2 | 2 | 4 | 107 | 43 | 64 | 60% | 3-4 | 4.11 | 1.32 |
| 2011-05-19 | Johnny Cueto | R | 25 | W 3-5 | vs PIT | 3 | 95 | L | 5.0 | 5 | 3 | 3 | 0 | 3 | 5 | 94 | 36 | 58 | 62% | 2-1 | 1.42 | 1.00 |
| 2011-05-20 | Travis Wood | L | 24 | L 4-5 | @ CLE | 10 | 27 | - | 5.1 | 3 | 4 | 4 | 0 | 2 | 3 | 94 | 41 | 53 | 56% | 3-3 | 5.14 | 1.39 |
| 2011-05-21 | Homer Bailey | R | 25 | L 1-2 | @ CLE | 4 | 60 | L | 7.0 | 4 | 2 | 2 | 1 | 0 | 4 | 105 | 36 | 69 | 66% | 3-1 | 2.08 | 0.88 |
| 2011-05-22 | Edinson Volquez | R | 28 | L 4-12 | @ CLE | 10 | 80 | L | 2.2 | 7 | 7 | 6 | 1 | 4 | 3 | 83 | 37 | 46 | 55% | 3-2 | 6.35 | 1.67 |
| 2011-05-23 | Bronson Arroyo | R | 34 | L 3-10 | @ PHI | 10 | 269 | L | 2.2 | 10 | 9 | 9 | 2 | 1 | 2 | 78 | 32 | 46 | 59% | 3-5 | 5.25 | 1.43 |
| 2011-05-24 | Johnny Cueto | R | 25 | W 6-3 | @ PHI | 4 | 96 | - | 6.0 | 7 | 3 | 3 | 0 | 2 | 1 | 108 | 39 | 69 | 64% | 2-1 | 2.16 | 1.12 |
| 2011-05-25 | Travis Wood | L | 24 | L 4-5 | @ PHI | 11 | 28 | - | 6.0 | 6 | 3 | 3 | 1 | 3 | 2 | 101 | 45 | 56 | 55% | 3-3 | 5.08 | 1.40 |
| 2011-05-26 | Homer Bailey | R | 25 | L 4-10 | @ PHI | 5 | 61 | - | 4.0 | 5 | 4 | 4 | 1 | 1 | 2 | 70 | 25 | 45 | 64% | 3-1 | 3.00 | 0.97 |
| 2011-05-27 | Mike Leake | R | 24 | W 5-1 | @ ATL | 7 | 29 | W | 6.0 | 7 | 1 | 1 | 0 | 3 | 2 | 96 | 41 | 55 | 57% | 4-2 | 5.14 | 1.43 |
| 2011-05-28 | Bronson Arroyo | R | 34 | L 6-7 | @ ATL | 11 | 270 | - | 3.0 | 9 | 5 | 5 | 2 | 1 | 0 | 62 | 22 | 40 | 65% | 3-5 | 5.71 | 1.52 |
| 2011-05-29 | Johnny Cueto | R | 25 | L 1-2 | @ ATL | 5 | 97 | L | 8.0 | 5 | 2 | 2 | 1 | 3 | 5 | 116 | 52 | 64 | 55% | 2-2 | 2.18 | 1.09 |
| 2011-05-30 | Travis Wood | L | 24 | L 7-3 | vs MIL | 12 | 29 | W | 6.0 | 7 | 3 | 3 | 2 | 0 | 2 | 95 | 30 | 65 | 68% | 4-3 | 5.03 | 1.38 |
| 2011-05-31 | Chad Reineke | R | 29 | W 2-7 | vs MIL | 1 | 5 | L | 6.1 | 5 | 6 | 5 | 2 | 5 | 2 | 99 | 47 | 52 | 53% | 0-1 | 7.50 | 1.67 |
| 2011-06-01 | Mike Leake | R | 24 | L 4-3 | vs MIL | 8 | 30 | - | 6.0 | 7 | 3 | 3 | 1 | 0 | 3 | 84 | 28 | 56 | 67% | 4-2 | 5.06 | 1.40 |
| 2011-06-03 | Bronson Arroyo | R | 34 | L 2-1 | vs LAN | 12 | 271 | W | 6.0 | 5 | 1 | 1 | 0 | 1 | 2 | 110 | 40 | 70 | 64% | 4-5 | 5.35 | 1.48 |
| 2011-06-04 | Johnny Cueto | R | 25 | W 8-11 | vs LAN | 6 | 98 | - | 7.0 | 5 | 2 | 2 | 1 | 1 | 3 | 85 | 31 | 54 | 64% | 2-2 | 2.25 | 1.05 |
| 2011-06-05 | Travis Wood | L | 24 | W 6-9 | vs LAN | 13 | 30 | L | 4.2 | 8 | 8 | 8 | 2 | 5 | 3 | 106 | 47 | 59 | 56% | 4-4 | 5.75 | 1.49 |
| 2011-06-06 | Mike Leake | R | 24 | L 8-2 | vs CHN | 9 | 31 | W | 8.0 | 10 | 2 | 2 | 0 | 1 | 3 | 114 | 40 | 74 | 65% | 5-2 | 4.66 | 1.39 |
| 2011-06-07 | Edinson Volquez | R | 28 | L 8-2 | vs CHN | 11 | 81 | W | 7.0 | 7 | 1 | 1 | 0 | 2 | 5 | 105 | 44 | 61 | 58% | 4-2 | 5.74 | 1.62 |
| 2011-06-08 | Bronson Arroyo | R | 34 | W 1-4 | vs CHN | 13 | 272 | L | 6.1 | 8 | 4 | 3 | 2 | 1 | 3 | 98 | 33 | 65 | 66% | 4-6 | 5.28 | 1.48 |
| 2011-06-09 | Johnny Cueto | R | 25 | W 3-0 | @ SFN | 7 | 99 | W | 7.0 | 4 | 0 | 0 | 0 | 2 | 8 | 113 | 48 | 65 | 58% | 3-2 | 1.91 | 1.02 |
| 2011-06-10 | Travis Wood | L | 24 | L 2-3 | @ SFN | 14 | 31 | - | 8.0 | 11 | 2 | 2 | 0 | 3 | 4 | 107 | 47 | 60 | 56% | 4-4 | 5.40 | 1.51 |
| 2011-06-11 | Mike Leake | R | 24 | W 10-2 | @ SFN | 10 | 32 | W | 8.0 | 4 | 0 | 0 | 0 | 1 | 8 | 113 | 41 | 72 | 64% | 6-2 | 4.08 | 1.30 |
| 2011-06-12 | Edinson Volquez | R | 28 | L 2-4 | @ SFN | 12 | 82 | - | 6.0 | 5 | 2 | 2 | 0 | 3 | 5 | 101 | 43 | 58 | 57% | 4-2 | 5.48 | 1.59 |
| 2011-06-13 | Bronson Arroyo | R | 34 | W 6-4 | @ LAN | 14 | 273 | W | 7.2 | 6 | 4 | 4 | 0 | 0 | 1 | 96 | 30 | 66 | 69% | 5-6 | 5.20 | 1.41 |
| 2011-06-14 | Johnny Cueto | R | 25 | W 3-2 | @ LAN | 8 | 100 | W | 7.0 | 5 | 1 | 0 | 0 | 1 | 5 | 103 | 31 | 72 | 70% | 4-2 | 1.67 | 1.00 |
| 2011-06-15 | Travis Wood | L | 24 | W 7-2 | @ LAN | 15 | 32 | W | 6.0 | 5 | 1 | 1 | 0 | 5 | 2 | 114 | 50 | 64 | 56% | 5-4 | 5.13 | 1.52 |
| 2011-06-17 | Mike Leake | R | 24 | W 2-3 | vs TOR | 11 | 33 | L | 7.0 | 5 | 3 | 3 | 1 | 0 | 3 | 85 | 30 | 55 | 65% | 6-3 | 4.06 | 1.24 |
| 2011-06-18 | Edinson Volquez | R | 28 | W 0-4 | vs TOR | 13 | 83 | L | 5.0 | 7 | 4 | 4 | 1 | 2 | 8 | 88 | 33 | 55 | 63% | 4-3 | 5.61 | 1.61 |
| 2011-06-19 | Bronson Arroyo | R | 34 | L 2-1 | vs TOR | 15 | 274 | W | 8.0 | 5 | 1 | 1 | 1 | 1 | 5 | 102 | 34 | 68 | 67% | 6-6 | 4.85 | 1.35 |
| 2011-06-20 | Travis Wood | L | 24 | W 3-5 | vs NYA | 16 | 33 | L | 7.0 | 8 | 4 | 4 | 0 | 1 | 6 | 106 | 33 | 73 | 69% | 5-5 | 5.13 | 1.51 |
| 2011-06-22 | Mike Leake | R | 24 | W 2-4 | vs NYA | 12 | 34 | L | 6.0 | 5 | 4 | 4 | 1 | 1 | 4 | 111 | 38 | 73 | 66% | 6-4 | 4.21 | 1.22 |
| 2011-06-22 | Johnny Cueto | R | 25 | L 10-2 | vs NYA | 9 | 101 | W | 7.0 | 2 | 1 | 1 | 1 | 3 | 6 | 102 | 41 | 61 | 60% | 5-2 | 1.62 | 0.97 |
| 2011-06-24 | Edinson Volquez | R | 28 | L 4-5 | @ BAL | 14 | 84 | - | 4.1 | 7 | 4 | 4 | 1 | 5 | 4 | 102 | 45 | 57 | 56% | 4-3 | 5.79 | 1.68 |
| 2011-06-25 | Bronson Arroyo | R | 34 | W 10-5 | @ BAL | 16 | 275 | W | 6.1 | 9 | 5 | 5 | 4 | 3 | 6 | 107 | 40 | 67 | 63% | 7-6 | 5.01 | 1.39 |
| 2011-06-26 | Homer Bailey | R | 25 | L 5-7 | @ BAL | 6 | 62 | L | 5.0 | 9 | 5 | 5 | 2 | 2 | 5 | 90 | 34 | 56 | 62% | 3-2 | 3.86 | 1.14 |
| 2011-06-27 | Mike Leake | R | 24 | W 5-0 | @ TBA | 13 | 35 | W | 6.0 | 4 | 0 | 0 | 0 | 2 | 3 | 99 | 42 | 57 | 58% | 7-4 | 3.90 | 1.20 |
| 2011-06-28 | Johnny Cueto | R | 25 | L 3-4 | @ TBA | 10 | 102 | - | 7.2 | 4 | 3 | 3 | 1 | 1 | 6 | 99 | 37 | 62 | 63% | 5-2 | 1.85 | 0.94 |
| 2011-06-29 | Edinson Volquez | R | 28 | W 4-3 | @ TBA | 15 | 85 | W | 6.1 | 4 | 3 | 3 | 1 | 3 | 7 | 98 | 39 | 59 | 60% | 5-3 | 5.63 | 1.63 |
| 2011-07-01 | Bronson Arroyo | R | 34 | W 2-8 | vs CLE | 17 | 276 | L | 4.2 | 9 | 8 | 8 | 3 | 0 | 2 | 91 | 26 | 65 | 71% | 7-7 | 5.47 | 1.41 |
| 2011-07-02 | Homer Bailey | R | 25 | W 1-3 | vs CLE | 7 | 63 | L | 7.0 | 8 | 3 | 2 | 1 | 1 | 7 | 104 | 28 | 76 | 73% | 3-3 | 3.64 | 1.17 |
| 2011-07-03 | Mike Leake | R | 24 | L 7-5 | vs CLE | 14 | 36 | W | 6.0 | 4 | 4 | 4 | 1 | 2 | 8 | 93 | 31 | 62 | 67% | 8-4 | 4.04 | 1.19 |
| 2011-07-04 | Johnny Cueto | R | 25 | L 0-1 | @ SLN | 11 | 103 | L | 8.0 | 6 | 1 | 1 | 0 | 3 | 0 | 108 | 44 | 64 | 59% | 5-3 | 1.78 | 0.96 |
| 2011-07-05 | Edinson Volquez | R | 28 | L 1-8 | @ SLN | 16 | 86 | L | 5.1 | 7 | 7 | 6 | 3 | 2 | 3 | 94 | 39 | 55 | 59% | 5-4 | 5.93 | 1.64 |
| 2011-07-06 | Bronson Arroyo | R | 34 | W 9-8 | @ SLN | 18 | 277 | - | 6.1 | 6 | 5 | 5 | 1 | 1 | 2 | 93 | 33 | 60 | 65% | 7-7 | 5.58 | 1.40 |
| 2011-07-07 | Homer Bailey | R | 25 | L 4-5 | @ MIL | 8 | 64 | L | 6.0 | 8 | 5 | 5 | 1 | 2 | 1 | 90 | 32 | 58 | 64% | 3-4 | 4.13 | 1.23 |
| 2011-07-08 | Mike Leake | R | 24 | L 7-8 | @ MIL | 15 | 37 | - | 5.1 | 7 | 5 | 5 | 2 | 1 | 3 | 78 | 24 | 54 | 69% | 8-4 | 4.26 | 1.20 |
| 2011-07-09 | Johnny Cueto | R | 25 | W 8-4 | @ MIL | 12 | 104 | - | 6.1 | 6 | 3 | 3 | 0 | 4 | 2 | 113 | 50 | 63 | 56% | 5-3 | 1.95 | 1.00 |
| 2011-07-10 | Dontrelle Willis | L | 29 | L 3-4 | @ MIL | 1 | 190 | - | 6.0 | 4 | 2 | 2 | 0 | 4 | 4 | 97 | 38 | 59 | 61% | 0-0 | 3.00 | 1.33 |
| 2011-07-15 | Johnny Cueto | R | 25 | L 6-5 | vs SLN | 13 | 105 | - | 7.0 | 5 | 3 | 2 | 0 | 2 | 2 | 85 | 32 | 53 | 62% | 5-3 | 2.00 | 1.00 |
| 2011-07-16 | Bronson Arroyo | R | 34 | W 1-4 | vs SLN | 19 | 278 | L | 6.2 | 8 | 4 | 4 | 1 | 2 | 5 | 97 | 35 | 62 | 64% | 7-8 | 5.56 | 1.40 |
| 2011-07-17 | Homer Bailey | R | 25 | L 3-1 | vs SLN | 9 | 65 | W | 7.1 | 3 | 1 | 1 | 1 | 3 | 4 | 85 | 37 | 48 | 56% | 4-4 | 3.76 | 1.18 |
| 2011-07-18 | Dontrelle Willis | L | 30 | L 0-2 | @ PIT | 2 | 191 | L | 4.2 | 5 | 2 | 2 | 0 | 1 | 5 | 69 | 18 | 51 | 74% | 0-1 | 3.27 | 1.27 |
| 2011-07-19 | Mike Leake | R | 24 | L 0-1 | @ PIT | 16 | 38 | L | 6.0 | 2 | 1 | 1 | 0 | 2 | 4 | 92 | 36 | 56 | 61% | 8-5 | 4.10 | 1.17 |
| 2011-07-20 | Johnny Cueto | R | 25 | W 3-1 | @ PIT | 14 | 106 | W | 6.0 | 4 | 1 | 1 | 0 | 2 | 4 | 97 | 36 | 61 | 63% | 6-3 | 1.97 | 1.00 |
| 2011-07-22 | Bronson Arroyo | R | 34 | W 4-6 | vs ATL | 20 | 279 | - | 6.2 | 9 | 4 | 4 | 3 | 2 | 2 | 85 | 34 | 51 | 60% | 7-8 | 5.58 | 1.42 |
| 2011-07-23 | Homer Bailey | R | 25 | L 11-2 | vs ATL | 10 | 66 | W | 6.0 | 5 | 2 | 2 | 0 | 3 | 3 | 108 | 47 | 61 | 56% | 5-4 | 3.69 | 1.20 |
| 2011-07-24 | Dontrelle Willis | L | 30 | L 4-3 | vs ATL | 3 | 192 | - | 6.1 | 7 | 3 | 3 | 1 | 3 | 3 | 88 | 31 | 57 | 65% | 0-1 | 3.71 | 1.41 |
| 2011-07-25 | Mike Leake | R | 24 | W 2-4 | vs NYN | 17 | 39 | L | 6.1 | 8 | 2 | 2 | 0 | 2 | 3 | 112 | 40 | 72 | 64% | 8-6 | 4.04 | 1.20 |
| 2011-07-26 | Johnny Cueto | R | 25 | W 6-8 | vs NYN | 15 | 107 | L | 5.0 | 7 | 6 | 0 | 0 | 1 | 5 | 110 | 43 | 67 | 61% | 6-4 | 1.87 | 1.03 |
| 2011-07-27 | Bronson Arroyo | R | 34 | W 2-8 | vs NYN | 21 | 280 | L | 6.0 | 7 | 5 | 4 | 1 | 3 | 3 | 96 | 34 | 62 | 65% | 7-9 | 5.60 | 1.43 |
| 2011-07-28 | Homer Bailey | R | 25 | W 9-10 | vs NYN | 11 | 67 | L | 4.0 | 12 | 9 | 9 | 0 | 2 | 2 | 74 | 23 | 51 | 69% | 5-5 | 4.71 | 1.34 |
| 2011-07-29 | Dontrelle Willis | L | 30 | L 4-3 | vs SFN | 4 | 193 | - | 6.0 | 6 | 2 | 2 | 0 | 2 | 3 | 103 | 38 | 65 | 63% | 0-1 | 3.52 | 1.39 |
| 2011-07-30 | Mike Leake | R | 24 | L 7-2 | vs SFN | 18 | 40 | W | 6.1 | 8 | 2 | 1 | 1 | 0 | 7 | 109 | 35 | 74 | 68% | 9-6 | 3.90 | 1.20 |
| 2011-07-31 | Johnny Cueto | R | 25 | L 9-0 | vs SFN | 16 | 108 | W | 9.0 | 3 | 0 | 0 | 0 | 1 | 6 | 109 | 29 | 80 | 73% | 7-4 | 1.72 | 0.98 |
| 2011-08-01 | Bronson Arroyo | R | 34 | L 3-4 | @ HOU | 22 | 281 | - | 8.0 | 6 | 3 | 3 | 0 | 2 | 3 | 94 | 31 | 63 | 67% | 7-9 | 5.47 | 1.41 |
| 2011-08-02 | Homer Bailey | R | 25 | W 5-1 | @ HOU | 12 | 68 | W | 8.0 | 5 | 1 | 1 | 0 | 3 | 4 | 99 | 36 | 63 | 64% | 6-5 | 4.32 | 1.30 |
| 2011-08-03 | Dontrelle Willis | L | 30 | L 4-5 | @ HOU | 5 | 194 | - | 6.0 | 8 | 2 | 2 | 1 | 1 | 2 | 78 | 30 | 48 | 62% | 0-1 | 3.41 | 1.41 |
| 2011-08-05 | Mike Leake | R | 24 | L 3-4 | @ CHN | 19 | 41 | L | 6.0 | 6 | 3 | 3 | 2 | 3 | 5 | 108 | 45 | 63 | 58% | 9-7 | 3.93 | 1.22 |
| 2011-08-06 | Johnny Cueto | R | 25 | L 4-11 | @ CHN | 17 | 109 | L | 3.2 | 7 | 5 | 5 | 1 | 3 | 2 | 84 | 40 | 44 | 52% | 7-5 | 2.07 | 1.04 |
| 2011-08-07 | Bronson Arroyo | R | 34 | W 8-7 | @ CHN | 23 | 282 | - | 6.0 | 5 | 4 | 4 | 2 | 3 | 4 | 108 | 40 | 68 | 63% | 7-9 | 5.49 | 1.40 |
| 2011-08-08 | Homer Bailey | R | 25 | W 7-10 | vs COL | 13 | 69 | - | 3.0 | 6 | 5 | 5 | 2 | 0 | 2 | 62 | 23 | 39 | 63% | 6-5 | 4.74 | 1.33 |
| 2011-08-09 | Dontrelle Willis | L | 30 | W 2-3 | vs COL | 6 | 195 | L | 8.0 | 5 | 3 | 3 | 1 | 1 | 10 | 107 | 35 | 72 | 67% | 0-2 | 3.41 | 1.27 |
| 2011-08-10 | Mike Leake | R | 24 | L 3-2 | vs COL | 20 | 42 | W | 7.1 | 11 | 2 | 2 | 1 | 1 | 5 | 99 | 34 | 65 | 66% | 10-7 | 3.83 | 1.24 |
| 2011-08-11 | Johnny Cueto | R | 25 | L 2-1 | vs COL | 18 | 110 | W | 7.0 | 3 | 0 | 0 | 0 | 2 | 9 | 119 | 44 | 75 | 63% | 8-5 | 1.95 | 1.03 |
| 2011-08-12 | Bronson Arroyo | R | 34 | L 5-3 | vs SDN | 24 | 283 | - | 6.0 | 6 | 2 | 1 | 1 | 2 | 6 | 120 | 46 | 74 | 62% | 7-9 | 5.33 | 1.40 |
| 2011-08-13 | Homer Bailey | R | 25 | L 13-1 | vs SDN | 14 | 70 | W | 7.0 | 6 | 1 | 1 | 1 | 1 | 7 | 116 | 37 | 79 | 68% | 7-5 | 4.45 | 1.30 |
| 2011-08-14 | Dontrelle Willis | L | 30 | W 3-7 | vs SDN | 7 | 196 | L | 2.2 | 6 | 4 | 4 | 0 | 2 | 1 | 63 | 27 | 36 | 57% | 0-3 | 4.05 | 1.38 |
| 2011-08-16 | Mike Leake | R | 24 | L 4-6 | @ WAS | 21 | 43 | L | 6.0 | 7 | 6 | 5 | 2 | 1 | 5 | 89 | 33 | 56 | 63% | 10-8 | 3.99 | 1.24 |
| 2011-08-17 | Johnny Cueto | R | 26 | W 2-1 | @ WAS | 19 | 111 | W | 8.0 | 6 | 1 | 1 | 1 | 0 | 5 | 103 | 36 | 67 | 65% | 9-5 | 1.90 | 1.01 |
| 2011-08-18 | Bronson Arroyo | R | 34 | L 1-3 | @ WAS | 25 | 284 | L | 6.0 | 7 | 3 | 3 | 1 | 2 | 3 | 101 | 40 | 61 | 60% | 7-10 | 5.29 | 1.41 |
| 2011-08-19 | Homer Bailey | R | 25 | W 11-8 | @ PIT | 15 | 71 | - | 5.0 | 6 | 3 | 3 | 0 | 3 | 6 | 95 | 33 | 62 | 65% | 7-5 | 4.50 | 1.33 |
| 2011-08-20 | Dontrelle Willis | L | 30 | L 3-5 | @ PIT | 8 | 197 | - | 6.0 | 8 | 3 | 3 | 0 | 3 | 5 | 101 | 36 | 65 | 64% | 0-3 | 4.11 | 1.43 |
| 2011-08-21 | Mike Leake | R | 24 | W 5-4 | @ PIT | 22 | 44 | - | 6.0 | 5 | 4 | 4 | 2 | 1 | 5 | 89 | 34 | 55 | 62% | 10-8 | 4.08 | 1.23 |
| 2011-08-23 | Johnny Cueto | R | 26 | W 8-6 | @ FLO | 20 | 112 | - | 5.0 | 4 | 3 | 3 | 0 | 6 | 3 | 105 | 45 | 60 | 57% | 9-5 | 2.03 | 1.05 |
| 2011-08-24 | Homer Bailey | R | 25 | L 5-6 | @ FLO | 16 | 72 | - | 7.0 | 5 | 3 | 3 | 2 | 0 | 4 | 102 | 35 | 67 | 66% | 7-5 | 4.45 | 1.28 |
| 2011-08-24 | Bronson Arroyo | R | 34 | W 3-2 | @ FLO | 26 | 285 | W | 8.0 | 6 | 0 | 0 | 0 | 0 | 1 | 107 | 39 | 68 | 64% | 8-10 | 5.03 | 1.37 |
| 2011-08-26 | Dontrelle Willis | L | 30 | L 4-3 | vs WAS | 9 | 198 | - | 7.0 | 6 | 3 | 3 | 1 | 5 | 4 | 123 | 52 | 71 | 58% | 0-3 | 4.08 | 1.45 |
| 2011-08-27 | Mike Leake | R | 24 | L 6-3 | vs WAS | 23 | 45 | W | 6.0 | 6 | 2 | 2 | 2 | 1 | 4 | 103 | 39 | 64 | 62% | 11-8 | 4.03 | 1.23 |
| 2011-08-28 | Johnny Cueto | R | 26 | L 5-4 | vs WAS | 21 | 113 | - | 7.0 | 9 | 2 | 2 | 0 | 1 | 11 | 118 | 45 | 73 | 62% | 9-5 | 2.06 | 1.06 |
| 2011-08-29 | Homer Bailey | R | 25 | W 2-3 | vs PHI | 17 | 73 | L | 8.0 | 6 | 3 | 3 | 1 | 0 | 9 | 100 | 27 | 73 | 73% | 7-6 | 4.37 | 1.24 |
| 2011-08-30 | Bronson Arroyo | R | 35 | W 0-9 | vs PHI | 27 | 286 | L | 5.1 | 8 | 6 | 5 | 2 | 2 | 2 | 91 | 29 | 62 | 68% | 8-11 | 5.12 | 1.38 |
| 2011-08-31 | Dontrelle Willis | L | 30 | W 0-3 | vs PHI | 10 | 199 | L | 6.2 | 5 | 3 | 3 | 1 | 5 | 6 | 119 | 54 | 65 | 55% | 0-4 | 4.12 | 1.47 |
| 2011-09-01 | Mike Leake | R | 24 | W 4-6 | vs PHI | 24 | 46 | L | 6.0 | 7 | 4 | 4 | 1 | 1 | 3 | 97 | 36 | 61 | 63% | 11-9 | 4.11 | 1.23 |
| 2011-09-02 | Johnny Cueto | R | 26 | W 11-8 | @ SLN | 22 | 114 | - | 5.0 | 8 | 5 | 5 | 1 | 2 | 2 | 78 | 26 | 52 | 67% | 9-5 | 2.30 | 1.10 |
| 2011-09-03 | Homer Bailey | R | 25 | L 4-6 | @ SLN | 18 | 74 | L | 3.0 | 6 | 5 | 4 | 0 | 1 | 3 | 69 | 25 | 44 | 64% | 7-7 | 4.58 | 1.27 |
| 2011-09-04 | Bronson Arroyo | R | 35 | W 3-2 | @ SLN | 28 | 287 | - | 8.0 | 10 | 2 | 2 | 1 | 0 | 5 | 111 | 37 | 74 | 67% | 8-11 | 4.99 | 1.38 |
| 2011-09-05 | Dontrelle Willis | L | 30 | L 3-4 | @ CHN | 11 | 200 | L | 7.0 | 6 | 4 | 4 | 0 | 5 | 8 | 108 | 38 | 70 | 65% | 0-5 | 4.23 | 1.48 |
| 2011-09-06 | Mike Leake | R | 24 | W 4-2 | @ CHN | 25 | 47 | - | 9.0 | 3 | 2 | 2 | 1 | 0 | 6 | 92 | 27 | 65 | 71% | 11-9 | 3.99 | 1.18 |
| 2011-09-07 | Johnny Cueto | R | 26 | L 3-6 | @ CHN | 23 | 115 | - | 7.0 | 7 | 3 | 3 | 0 | 0 | 3 | 105 | 36 | 69 | 66% | 9-5 | 2.37 | 1.09 |
| 2011-09-09 | Homer Bailey | R | 25 | W 4-1 | @ COL | 19 | 75 | W | 7.2 | 6 | 1 | 1 | 1 | 1 | 6 | 115 | 41 | 74 | 64% | 8-7 | 4.34 | 1.25 |
| 2011-09-10 | Bronson Arroyo | R | 35 | L 7-12 | @ COL | 29 | 288 | - | 1.0 | 7 | 6 | 6 | 3 | 0 | 1 | 42 | 13 | 29 | 69% | 8-11 | 5.27 | 1.41 |
| 2011-09-11 | Edinson Volquez | R | 28 | L 1-4 | @ COL | 17 | 87 | L | 5.0 | 4 | 2 | 2 | 1 | 4 | 3 | 108 | 50 | 58 | 54% | 5-5 | 5.80 | 1.63 |
| 2011-09-12 | Dontrelle Willis | L | 30 | W 8-12 | vs CHN | 12 | 201 | L | 3.1 | 9 | 8 | 8 | 1 | 3 | 0 | 73 | 27 | 46 | 63% | 0-6 | 5.01 | 1.57 |
| 2011-09-13 | Mike Leake | R | 24 | L 2-1 | vs CHN | 26 | 48 | W | 8.0 | 6 | 1 | 1 | 0 | 2 | 2 | 91 | 29 | 62 | 68% | 12-9 | 3.86 | 1.17 |
| 2011-09-14 | Johnny Cueto | R | 26 | L 7-2 | vs CHN | 24 | 116 | - | 3.2 | 3 | 0 | 0 | 0 | 1 | 2 | 46 | 16 | 30 | 65% | 9-5 | 2.31 | 1.09 |
| 2011-09-15 | Homer Bailey | R | 25 | L 8-6 | vs CHN | 20 | 76 | - | 6.0 | 6 | 4 | 4 | 2 | 3 | 9 | 103 | 37 | 66 | 64% | 8-7 | 4.43 | 1.26 |
| 2011-09-16 | Bronson Arroyo | R | 35 | W 3-6 | vs MIL | 30 | 289 | L | 6.1 | 5 | 5 | 5 | 4 | 3 | 2 | 114 | 43 | 71 | 62% | 8-12 | 5.34 | 1.41 |
| 2011-09-17 | Edinson Volquez | R | 28 | W 1-10 | vs MIL | 18 | 88 | L | 6.2 | 6 | 5 | 5 | 1 | 3 | 6 | 117 | 42 | 75 | 64% | 5-6 | 5.85 | 1.61 |
| 2011-09-18 | Matt Maloney | L | 28 | W 1-8 | vs MIL | 2 | 11 | L | 1.2 | 9 | 7 | 6 | 2 | 0 | 0 | 49 | 18 | 31 | 63% | 0-3 | 9.00 | 2.11 |
| 2011-09-19 | Travis Wood | L | 25 | W 2-3 | vs HOU | 17 | 34 | - | 5.0 | 4 | 0 | 0 | 0 | 2 | 2 | 69 | 25 | 44 | 64% | 6-5 | 4.63 | 1.45 |
| 2011-09-20 | Homer Bailey | R | 25 | L 6-4 | vs HOU | 21 | 77 | W | 7.0 | 6 | 2 | 2 | 1 | 2 | 5 | 119 | 42 | 77 | 65% | 9-7 | 4.32 | 1.25 |
| 2011-09-21 | Bronson Arroyo | R | 35 | L 2-0 | vs HOU | 31 | 290 | W | 9.0 | 6 | 0 | 0 | 0 | 0 | 2 | 91 | 27 | 64 | 70% | 9-12 | 5.09 | 1.37 |
| 2011-09-23 | Edinson Volquez | R | 28 | L 3-4 | @ PIT | 19 | 89 | - | 5.0 | 6 | 3 | 3 | 1 | 2 | 5 | 95 | 37 | 58 | 61% | 5-6 | 5.82 | 1.61 |
| 2011-09-24 | Travis Wood | L | 25 | L 3-4 | @ PIT | 18 | 35 | L | 2.2 | 7 | 4 | 4 | 0 | 2 | 2 | 68 | 24 | 44 | 65% | 6-6 | 4.84 | 1.49 |
| 2011-09-25 | Dontrelle Willis | L | 30 | W 5-4 | @ PIT | 13 | 202 | W | 6.0 | 3 | 3 | 3 | 0 | 2 | 6 | 104 | 44 | 60 | 58% | 1-6 | 4.97 | 1.51 |
| 2011-09-26 | Homer Bailey | R | 25 | W 6-5 | @ NYN | 22 | 78 | - | 5.0 | 9 | 4 | 4 | 0 | 1 | 7 | 103 | 39 | 64 | 62% | 9-7 | 4.43 | 1.28 |
| 2011-09-27 | Bronson Arroyo | R | 35 | W 5-4 | @ NYN | 32 | 291 | - | 8.0 | 9 | 4 | 4 | 2 | 1 | 6 | 125 | 45 | 80 | 64% | 9-12 | 5.07 | 1.37 |
| 2011-09-28 | Edinson Volquez | R | 28 | L 0-3 | @ NYN | 20 | 90 | L | 7.0 | 6 | 3 | 3 | 1 | 1 | 5 | 98 | 26 | 72 | 73% | 5-7 | 5.70 | 1.57 |