| Central | W | L | Pct | GB |
| Detroit | 95 | 67 | .586 | -- |
| Cleveland | 80 | 82 | .494 | 15.0 |
| Chi White Sox | 79 | 83 | .488 | 16.0 |
| KC Royals | 71 | 91 | .438 | 24.0 |
| Minnesota | 63 | 99 | .389 | 32.0 |
| # | Player | Pos | Rk | Age | Drafted | HiLvl | G | AB | R | H | 2B | 3B | HR | RBI | SB | CS | BB | SO | HBP | IBB | SH | SF | DP | AVG | OBP | SLG | OPS | TB | PA | OUT | RC | RC/G | babip |
| 1 | Juan Pierre | lf | 14 | 33 | 1998-13-390 | MLB | 158 | 639 | 80 | 178 | 17 | 4 | 2 | 50 | 27 | 17 | 43 | 41 | 7 | 0 | 19 | 3 | 7 | .279 | .329 | .327 | 657 | 209 | 711 | 507 | 78 | 4.1 | .294 |
| 10 | Alexei Ramirez | ss | 38 | 29 | - | MLB | 158 | 614 | 81 | 165 | 31 | 2 | 15 | 70 | 7 | 5 | 51 | 84 | 6 | 1 | 8 | 5 | 19 | .269 | .328 | .399 | 727 | 245 | 684 | 486 | 85 | 4.7 | .288 |
| 14 | Paul Konerko | 1b | 9 | 35 | 1994-1-13 | MLB | 149 | 543 | 69 | 163 | 25 | 0 | 31 | 105 | 1 | 1 | 77 | 89 | 8 | 17 | 0 | 11 | 14 | .300 | .388 | .517 | 906 | 281 | 639 | 406 | 116 | 7.7 | .304 |
| 51 | Alex Rios | rf | - | 30 | 1999-1-19 | MLB | 145 | 537 | 64 | 122 | 22 | 2 | 13 | 44 | 11 | 6 | 27 | 68 | 2 | 4 | 0 | 4 | 20 | .227 | .265 | .348 | 613 | 187 | 570 | 445 | 48 | 2.9 | .237 |
| 15 | Gordon Beckham | 2b | 40 | 24 | 2008-1-8 | MLB | 150 | 499 | 60 | 115 | 23 | 0 | 10 | 44 | 5 | 3 | 35 | 111 | 13 | 0 | 7 | 3 | 6 | .230 | .296 | .337 | 633 | 168 | 557 | 403 | 50 | 3.3 | .276 |
| 12 | A.J. Pierzynski | c | 90 | 34 | 1994-3-71 | MLB | 129 | 464 | 38 | 133 | 29 | 1 | 8 | 48 | 0 | 0 | 23 | 33 | 5 | 6 | 2 | 6 | 19 | .287 | .323 | .405 | 728 | 188 | 500 | 358 | 66 | 4.9 | .291 |
| 20 | Carlos Quentin | lf | 55 | 28 | 2003-1-29 | MLB | 118 | 421 | 53 | 107 | 31 | 0 | 24 | 77 | 1 | 1 | 34 | 84 | 23 | 0 | 0 | 5 | 7 | .254 | .340 | .499 | 838 | 210 | 483 | 327 | 79 | 6.5 | .261 |
| 32 | Adam Dunn | dh-1b | 49 | 31 | 1998-2-50 | MLB | 122 | 415 | 36 | 66 | 16 | 0 | 11 | 42 | 0 | 1 | 75 | 177 | 4 | 0 | 0 | 2 | 10 | .159 | .292 | .277 | 569 | 115 | 496 | 362 | 23 | 1.7 | .240 |
| 22 | Brent Morel | 3b | - | 24 | 2008-3-86 | MLB | 126 | 413 | 44 | 101 | 18 | 1 | 10 | 41 | 5 | 4 | 22 | 57 | 3 | 0 | 5 | 1 | 8 | .245 | .287 | .366 | 653 | 151 | 444 | 330 | 45 | 3.7 | .262 |
| 18 | Brent Lillibridge | 1b-ss | - | 27 | 2005-4-121 | MLB | 97 | 186 | 38 | 48 | 5 | 1 | 13 | 29 | 10 | 6 | 17 | 62 | 7 | 1 | 4 | 2 | 2 | .258 | .340 | .505 | 845 | 94 | 216 | 152 | 31 | 5.5 | .310 |
| 11 | Omar Vizquel | 2b-3b | - | 44 | UDFA: 1984 | MLB | 58 | 167 | 18 | 42 | 7 | 1 | 0 | 8 | 1 | 2 | 9 | 18 | 0 | 0 | 4 | 2 | 2 | .251 | .287 | .305 | 592 | 51 | 182 | 135 | 15 | 3.1 | .278 |
| 30 | Alejandro De Aza | cf | - | 27 | UDFA: 2001 | MLB | 54 | 152 | 29 | 50 | 11 | 3 | 4 | 23 | 12 | 5 | 17 | 34 | 1 | 1 | 1 | 0 | 2 | .329 | .400 | .520 | 920 | 79 | 171 | 110 | 33 | 8.1 | .404 |
| 23 | Mark Teahen | 1b | - | 29 | 2002-1-39 | MLB | 51 | 118 | 11 | 24 | 3 | 0 | 3 | 11 | 0 | 1 | 12 | 28 | 0 | 1 | 0 | 0 | 3 | .203 | .277 | .305 | 582 | 36 | 130 | 98 | 8 | 2.2 | .241 |
| 17 | Tyler Flowers | c | - | 25 | 2005-33-1007 | MLB | 38 | 110 | 13 | 23 | 5 | 1 | 5 | 16 | 0 | 1 | 14 | 38 | 3 | 0 | 0 | 2 | 2 | .209 | .310 | .409 | 719 | 45 | 129 | 92 | 13 | 3.9 | .261 |
| 24 | Dayan Viciedo | lf | - | 22 | UDFA: 2009 | MLB | 29 | 102 | 11 | 26 | 3 | 0 | 1 | 6 | 1 | 0 | 9 | 23 | 2 | 0 | 0 | 0 | 4 | .255 | .327 | .314 | 641 | 32 | 113 | 80 | 9 | 3.2 | .321 |
| 27 | Ramon Castro | c | - | 35 | 1994-1-17 | MLB | 23 | 68 | 6 | 16 | 3 | 0 | 4 | 10 | 0 | 0 | 7 | 23 | 0 | 0 | 0 | 0 | 0 | .235 | .307 | .456 | 763 | 31 | 75 | 52 | 9 | 4.9 | .293 |
| 45 | Dallas McPherson | 3b | - | 30 | 2001-2-57 | MLB | 11 | 15 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | .133 | .133 | .133 | 267 | 2 | 15 | 13 | -1 | -2.1 | .250 |
| 55 | Donny Lucy | c | - | 28 | 2004-2-59 | MLB | 6 | 10 | 1 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | .200 | .273 | .300 | 573 | 3 | 11 | 8 | 1 | 1.9 | .400 |
| 62 | Eduardo Escobar | 3b-2b | - | 22 | UDFA: 2008 | MLB | 9 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | .286 | .286 | .286 | 571 | 2 | 7 | 5 | 1 | 2.8 | .333 |
| 41 | Philip Humber | p | - | 28 | 2004-1-3 | MLB | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 6 | 6 | - | - | .000 |
| 33 | Edwin Jackson | p | - | 27 | 2001-6-190 | MLB | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 4 | 4 | - | - | .000 |
| 5 | Lastings Milledge | lf-rf | - | 26 | 2003-1-12 | MLB | 2 | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | .250 | .250 | .500 | 750 | 2 | 4 | 3 | 1 | 5.8 | .333 |
| 34 | Gavin Floyd | p | - | 28 | 2001-1-4 | MLB | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | .000 | .250 | .000 | 250 | 0 | 5 | 4 | 0 | -0.4 | .000 |
| 50 | John Danks | p | - | 26 | 2003-1-9 | MLB | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 3 | 3 | - | - | .000 |
| 56 | Mark Buehrle | p | - | 32 | 1998-38-1139 | MLB | 1 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | .500 | .500 | 1.000 | 1500 | 2 | 2 | 1 | 1 | 24.6 | 1.000 |
| 44 | Jake Peavy | p | - | 30 | 1999-15-472 | MLB | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .500 | .000 | 500 | 0 | 2 | 1 | 0 | 6.1 | .000 |
| Totals: (26 players) | 162 | 5502 | 654 | 1387 | 252 | 16 | 154 | 625 | 81 | 53 | 475 | 989 | 84 | 31 | 52 | 46 | 125 | .252 | .319 | .388 | 707 | 2133 | 6159 | 4391 | 706 | 4.3 | .280 | ||||||
| # | Player | Rk | Age | Drafted | HiLvl | W | L | ERA | G | GS | CG | SH | GF | SV | IP | H | R | ER | HR | BB | SO | WP | Bk | WHIP | H9 | HR9 | BB9 | SO9 | BB/SO | BABIP | GB/FB |
| 56 | Mark Buehrle | 36 | 32 | 1998-38-1139 | MLB | 13 | 9 | 3.59 | 31 | 31 | 0 | 0 | 0 | 0 | 205.1 | 221 | 93 | 82 | 21 | 45 | 109 | 1 | 0 | 1.30 | 9.69 | 0.92 | 1.97 | 4.78 | 0.41 | .299 | 0.87 |
| 34 | Gavin Floyd | 31 | 28 | 2001-1-4 | MLB | 12 | 13 | 4.37 | 31 | 30 | 1 | 0 | 1 | 0 | 193.2 | 180 | 97 | 94 | 22 | 45 | 151 | 12 | 1 | 1.16 | 8.36 | 1.02 | 2.09 | 7.02 | 0.30 | .284 | 0.84 |
| 50 | John Danks | 52 | 26 | 2003-1-9 | MLB | 8 | 12 | 4.33 | 27 | 27 | 2 | 1 | 0 | 0 | 170.1 | 182 | 89 | 82 | 19 | 46 | 135 | 6 | 0 | 1.34 | 9.62 | 1.00 | 2.43 | 7.13 | 0.34 | .319 | 0.84 |
| 41 | Philip Humber | 41 | 28 | 2004-1-3 | MLB | 9 | 9 | 3.75 | 28 | 26 | 0 | 0 | 0 | 0 | 163.0 | 151 | 71 | 68 | 14 | 41 | 116 | 9 | 1 | 1.18 | 8.34 | 0.77 | 2.26 | 6.40 | 0.35 | .278 | 0.94 |
| 33 | Edwin Jackson | 74 | 27 | 2001-6-190 | MLB | 7 | 7 | 3.92 | 19 | 19 | 1 | 1 | 0 | 0 | 121.2 | 134 | 55 | 53 | 8 | 39 | 97 | 7 | 1 | 1.42 | 9.91 | 0.59 | 2.88 | 7.18 | 0.40 | .342 | 0.94 |
| 44 | Jake Peavy | 88 | 30 | 1999-15-472 | MLB | 7 | 7 | 4.92 | 19 | 18 | 1 | 1 | 0 | 0 | 111.2 | 117 | 61 | 61 | 10 | 24 | 95 | 4 | 0 | 1.26 | 9.43 | 0.81 | 1.93 | 7.66 | 0.25 | .322 | 0.67 |
| 49 | Chris Sale | 87 | 22 | 2010-1-13 | MLB | 2 | 2 | 2.79 | 58 | 0 | 0 | 0 | 17 | 8 | 71.0 | 52 | 22 | 22 | 6 | 27 | 79 | 2 | 0 | 1.11 | 6.59 | 0.76 | 3.42 | 10.01 | 0.34 | .269 | 1.07 |
| 26 | Jesse Crain | 72 | 29 | 2002-2-61 | MLB | 8 | 3 | 2.62 | 67 | 0 | 0 | 0 | 11 | 1 | 65.1 | 50 | 20 | 19 | 7 | 31 | 70 | 0 | 1 | 1.24 | 6.89 | 0.96 | 4.27 | 9.64 | 0.44 | .276 | 0.56 |
| 46 | Sergio Santos | 45 | 27 | 2002-1-27 | MLB | 4 | 5 | 3.55 | 63 | 0 | 0 | 0 | 50 | 30 | 63.1 | 41 | 25 | 25 | 6 | 29 | 92 | 5 | 0 | 1.11 | 5.83 | 0.85 | 4.12 | 13.07 | 0.32 | .273 | 0.74 |
| 37 | Matt Thornton | - | 34 | 1998-1-22 | MLB | 2 | 5 | 3.32 | 62 | 0 | 0 | 0 | 20 | 3 | 59.2 | 60 | 34 | 22 | 3 | 21 | 63 | 2 | 0 | 1.36 | 9.05 | 0.45 | 3.17 | 9.50 | 0.33 | .337 | 0.96 |
| 77 | Will Ohman | - | 33 | 1998-8-226 | MLB | 1 | 3 | 4.22 | 59 | 0 | 0 | 0 | 15 | 0 | 53.1 | 53 | 26 | 25 | 8 | 17 | 54 | 1 | 0 | 1.31 | 8.94 | 1.35 | 2.87 | 9.11 | 0.31 | .308 | 0.73 |
| 48 | Zach Stewart | - | 24 | 2008-3-84 | MLB | 2 | 5 | 6.22 | 10 | 8 | 1 | 1 | 1 | 0 | 50.2 | 64 | 35 | 35 | 9 | 13 | 35 | 1 | 0 | 1.52 | 11.37 | 1.60 | 2.31 | 6.22 | 0.37 | .344 | 1.09 |
| 57 | Tony Pena | - | 29 | UDFA: 2002 | MLB | 1 | 1 | 6.20 | 17 | 0 | 0 | 0 | 10 | 0 | 20.1 | 25 | 15 | 14 | 2 | 10 | 17 | 0 | 0 | 1.72 | 11.07 | 0.89 | 4.43 | 7.52 | 0.59 | .359 | 0.94 |
| 40 | Brian Bruney | - | 29 | 2000-12-369 | MLB | 1 | 0 | 6.86 | 23 | 0 | 0 | 0 | 6 | 0 | 19.2 | 26 | 15 | 15 | 4 | 12 | 16 | 0 | 0 | 1.93 | 11.90 | 1.83 | 5.49 | 7.32 | 0.75 | .386 | 0.76 |
| 3 | Dylan Axelrod | - | 25 | 2007-30-927 | MLB | 1 | 0 | 2.89 | 4 | 3 | 0 | 0 | 1 | 0 | 18.2 | 18 | 6 | 6 | 1 | 9 | 19 | 0 | 0 | 1.45 | 8.68 | 0.48 | 4.34 | 9.16 | 0.47 | .340 | 0.77 |
| 58 | Jason Frasor | - | 33 | 1999-33-987 | MLB | 1 | 2 | 5.09 | 20 | 0 | 0 | 0 | 4 | 0 | 17.2 | 20 | 10 | 10 | 3 | 11 | 20 | 1 | 0 | 1.75 | 10.19 | 1.53 | 5.60 | 10.19 | 0.55 | -- | 0.55 |
| 52 | Josh Kinney | - | 32 | UDFA: 2001 | MLB | 0 | 0 | 6.62 | 13 | 0 | 0 | 0 | 8 | 0 | 17.2 | 23 | 13 | 13 | 1 | 7 | 20 | 1 | 0 | 1.70 | 11.72 | 0.51 | 3.57 | 10.19 | 0.35 | .431 | 1.36 |
| 60 | Jeff Gray | - | 29 | 2004-32-967 | MLB | 0 | 0 | 2.70 | 6 | 0 | 0 | 0 | 5 | 0 | 13.1 | 13 | 4 | 4 | 1 | 4 | 7 | 1 | 0 | 1.28 | 8.78 | 0.68 | 2.70 | 4.73 | 0.57 | .279 | 0.73 |
| 43 | Addison Reed | - | 22 | 2010-3-95 | MLB | 0 | 0 | 3.68 | 6 | 0 | 0 | 0 | 2 | 0 | 7.1 | 10 | 3 | 3 | 1 | 1 | 12 | 0 | 0 | 1.50 | 12.27 | 1.23 | 1.23 | 14.73 | 0.08 | .474 | 0.25 |
| 66 | Shane Lindsay | - | 26 | UDFA: 2003 | MLB | 0 | 0 | 12.00 | 4 | 0 | 0 | 0 | 2 | 0 | 6.0 | 11 | 8 | 8 | 1 | 5 | 6 | 1 | 0 | 2.67 | 16.50 | 1.50 | 7.50 | 9.00 | 0.83 | .455 | 0.53 |
| 60 | Hector Santiago | - | 23 | 2006-30-915 | MLB | 0 | 0 | 0.00 | 2 | 0 | 0 | 0 | 1 | 0 | 5.1 | 1 | 0 | 0 | 0 | 1 | 2 | 1 | 0 | 0.38 | 1.69 | 0.00 | 1.69 | 3.38 | 0.50 | .067 | 1.50 |
| 58 | Lucas Harrell | - | 26 | 2004-4-119 | MLB | 0 | 0 | 7.20 | 3 | 0 | 0 | 0 | 2 | 0 | 5.0 | 11 | 4 | 4 | 0 | 1 | 5 | 0 | 0 | 2.40 | 19.80 | 0.00 | 1.80 | 9.00 | 0.20 | .550 | 1.50 |
| Totals: (26 players) | 79 | 83 | 4.10 | 162 | 162 | 6 | 4 | 156 | 42 | 1,460 | 1463 | 706 | 665 | 154 | 439 | 1220 | 55 | 4 | 1.28 | 9.02 | 0.91 | 2.71 | 7.52 | 0.36 | .314 | ||||||
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| A.J. Pierzynski | c | 120 | 1008 | 817 | 65 | 4 | 4 | .995 | 7.88 | |
| Tyler Flowers | c | 31 | 256 | 243 | 15 | 2 | 1 | .992 | 9.06 | |
| Ramon Castro | c | 21 | 174 | 117 | 4 | 1 | 0 | .992 | 6.26 | |
| Donny Lucy | c | 3 | 21 | 23 | 1 | 0 | 1 | 1.000 | 10.29 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Paul Konerko | 1b | 111 | 963 | 975 | 68 | 5 | 89 | .995 | 9.75 | |
| Adam Dunn | 1b | 35 | 284 | 259 | 24 | 4 | 21 | .986 | 8.96 | |
| Brent Lillibridge | 1b | 22 | 127 | 114 | 11 | 2 | 9 | .984 | 8.86 | |
| Mark Teahen | 1b | 11 | 32 | 40 | 1 | 0 | 1 | 1.000 | 11.53 | |
| Dallas McPherson | 1b | 6 | 8 | 7 | 0 | 0 | 0 | 1.000 | 7.88 | |
| Dayan Viciedo | 1b | 4 | 21 | 18 | 1 | 0 | 1 | 1.000 | 8.14 | |
| Tyler Flowers | 1b | 3 | 21 | 17 | 4 | 0 | 2 | 1.000 | 9.00 | |
| Omar Vizquel | 1b | 1 | 3 | 1 | 1 | 0 | 0 | 1.000 | 6.00 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Gordon Beckham | 2b | 149 | 1307 | 272 | 443 | 8 | 84 | .989 | 4.92 | |
| Omar Vizquel | 2b | 16 | 130 | 23 | 37 | 1 | 7 | .984 | 4.15 | |
| Brent Lillibridge | 2b | 6 | 19 | 5 | 4 | 0 | 2 | 1.000 | 4.26 | |
| Eduardo Escobar | 2b | 2 | 3 | 2 | 1 | 0 | 1 | 1.000 | 9.00 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Brent Morel | 3b | 125 | 1058 | 72 | 211 | 14 | 13 | .953 | 2.41 | |
| Omar Vizquel | 3b | 29 | 182 | 13 | 31 | 0 | 2 | 1.000 | 2.18 | |
| Mark Teahen | 3b | 28 | 191 | 17 | 38 | 0 | 1 | 1.000 | 2.59 | |
| Dallas McPherson | 3b | 5 | 28 | 2 | 9 | 0 | 0 | 1.000 | 3.52 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Alexei Ramirez | ss | 155 | 1382 | 217 | 457 | 16 | 99 | .977 | 4.39 | |
| Omar Vizquel | ss | 9 | 72 | 8 | 18 | 0 | 3 | 1.000 | 3.25 | |
| Eduardo Escobar | ss | 3 | 6 | 0 | 4 | 0 | 0 | 1.000 | 6.00 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Juan Pierre | lf | 155 | 1365 | 278 | 5 | 7 | 1 | .976 | 1.87 | |
| Brent Lillibridge | lf | 9 | 60 | 16 | 0 | 0 | 0 | 1.000 | 2.40 | |
| Alejandro De Aza | lf | 4 | 21 | 9 | 0 | 0 | 0 | 1.000 | 3.86 | |
| Mark Teahen | lf | 3 | 3 | 0 | 0 | 1 | 0 | .000 | 0.00 | |
| Lastings Milledge | lf | 2 | 11 | 7 | 0 | 0 | 0 | 1.000 | 5.73 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Alex Rios | cf | 143 | 1230 | 349 | 5 | 3 | 3 | .992 | 2.59 | |
| Alejandro De Aza | cf | 19 | 153 | 49 | 0 | 1 | 0 | .980 | 2.88 | |
| Brent Lillibridge | cf | 11 | 76 | 26 | 0 | 0 | 0 | 1.000 | 3.07 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Carlos Quentin | rf | 102 | 854 | 177 | 2 | 1 | 0 | .994 | 1.89 | |
| Brent Lillibridge | rf | 43 | 203 | 45 | 0 | 0 | 0 | 1.000 | 2.00 | |
| Alejandro De Aza | rf | 31 | 202 | 46 | 2 | 0 | 0 | 1.000 | 2.14 | |
| Dayan Viciedo | rf | 21 | 163 | 26 | 2 | 0 | 1 | 1.000 | 1.55 | |
| Mark Teahen | rf | 6 | 23 | 2 | 0 | 0 | 0 | 1.000 | 0.78 | |
| Adam Dunn | rf | 2 | 14 | 1 | 0 | 0 | 0 | 1.000 | 0.64 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Jesse Crain | p | 67 | 65 | 3 | 11 | 1 | 1 | .933 | 1.94 | |
| Sergio Santos | p | 63 | 63 | 5 | 4 | 0 | 3 | 1.000 | 1.28 | |
| Matt Thornton | p | 62 | 59 | 5 | 7 | 0 | 0 | 1.000 | 1.82 | |
| Will Ohman | p | 59 | 53 | 1 | 6 | 0 | 0 | 1.000 | 1.19 | |
| Chris Sale | p | 58 | 71 | 5 | 15 | 0 | 0 | 1.000 | 2.54 | |
| Mark Buehrle | p | 31 | 205 | 15 | 40 | 1 | 4 | .982 | 2.41 | |
| Gavin Floyd | p | 31 | 193 | 13 | 21 | 1 | 6 | .971 | 1.58 | |
| Philip Humber | p | 28 | 163 | 12 | 15 | 1 | 0 | .964 | 1.49 | |
| John Danks | p | 27 | 170 | 4 | 30 | 0 | 1 | 1.000 | 1.80 | |
| Brian Bruney | p | 23 | 19 | 1 | 3 | 0 | 0 | 1.000 | 1.88 | |
| Jason Frasor | p | 20 | 17 | 0 | 3 | 0 | 0 | 1.000 | 1.57 | |
| Edwin Jackson | p | 19 | 121 | 4 | 18 | 2 | 0 | .917 | 1.63 | |
| Jake Peavy | p | 19 | 111 | 9 | 6 | 1 | 0 | .937 | 1.21 | |
| Tony Pena | p | 17 | 20 | 0 | 2 | 0 | 0 | 1.000 | 0.90 | |
| Josh Kinney | p | 13 | 17 | 0 | 4 | 0 | 1 | 1.000 | 2.09 | |
| Zach Stewart | p | 10 | 50 | 4 | 9 | 2 | 0 | .867 | 2.33 | |
| Jeff Gray | p | 6 | 13 | 1 | 3 | 0 | 1 | 1.000 | 2.75 | |
| Addison Reed | p | 6 | 7 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Dylan Axelrod | p | 4 | 18 | 3 | 4 | 0 | 2 | 1.000 | 3.46 | |
| Shane Lindsay | p | 4 | 6 | 1 | 1 | 0 | 0 | 1.000 | 3.00 | |
| Lucas Harrell | p | 3 | 5 | 1 | 0 | 0 | 0 | 1.000 | 1.80 | |
| Hector Santiago | p | 2 | 5 | 0 | 1 | 0 | 0 | 1.000 | 1.76 |