| Central | W | L | Pct | GB |
| Milwaukee | 96 | 66 | .593 | -- |
| St. Louis | 90 | 72 | .556 | 6.0 |
| Cincinnati | 79 | 83 | .488 | 17.0 |
| Pittsburgh | 72 | 90 | .444 | 24.0 |
| Chi Cubs | 71 | 91 | .438 | 25.0 |
| Houston | 56 | 106 | .346 | 40.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2011-04-02 | Jake Westbrook | R | 34 | W 3-11 | vs SDN | 1 | 194 | L | 4.1 | 6 | 8 | 8 | 0 | 5 | 3 | 89 | 37 | 52 | 58% | 0-1 | 18.00 | 2.75 |
| 2011-04-03 | Jaime Garcia | L | 25 | L 2-0 | vs SDN | 1 | 30 | W | 9.0 | 4 | 0 | 0 | 0 | 2 | 9 | 102 | 37 | 65 | 64% | 1-0 | 0.00 | 0.67 |
| 2011-04-04 | Kyle Lohse | R | 32 | W 3-4 | vs PIT | 1 | 269 | L | 7.0 | 6 | 4 | 4 | 1 | 1 | 5 | 93 | 35 | 58 | 62% | 0-1 | 5.14 | 1.00 |
| 2011-04-05 | Kyle McClellan | R | 27 | L 3-2 | vs PIT | 1 | 1 | - | 6.0 | 6 | 2 | 2 | 1 | 1 | 7 | 92 | 35 | 57 | 62% | 0-0 | 3.00 | 1.17 |
| 2011-04-06 | Chris Carpenter | R | 36 | W 1-3 | vs PIT | 2 | 297 | L | 6.0 | 8 | 2 | 1 | 1 | 0 | 6 | 106 | 39 | 67 | 63% | 0-1 | 2.08 | 0.92 |
| 2011-04-08 | Jake Westbrook | R | 34 | L 4-5 | @ SFN | 2 | 195 | - | 5.2 | 8 | 3 | 3 | 2 | 4 | 2 | 108 | 47 | 61 | 56% | 0-1 | 9.90 | 2.30 |
| 2011-04-09 | Jaime Garcia | L | 25 | L 2-3 | @ SFN | 2 | 31 | - | 6.0 | 4 | 1 | 1 | 0 | 1 | 9 | 85 | 27 | 58 | 68% | 1-0 | 0.60 | 0.73 |
| 2011-04-10 | Kyle Lohse | R | 33 | W 6-1 | @ SFN | 2 | 270 | W | 8.0 | 5 | 1 | 1 | 0 | 0 | 5 | 95 | 31 | 64 | 67% | 1-1 | 3.00 | 0.80 |
| 2011-04-11 | Kyle McClellan | R | 27 | W 8-2 | @ ARI | 2 | 2 | W | 6.0 | 7 | 1 | 1 | 0 | 4 | 4 | 98 | 44 | 54 | 55% | 1-0 | 2.25 | 1.50 |
| 2011-04-12 | Chris Carpenter | R | 36 | L 8-13 | @ ARI | 3 | 298 | L | 4.0 | 8 | 8 | 8 | 2 | 3 | 4 | 82 | 38 | 44 | 54% | 0-2 | 5.82 | 1.35 |
| 2011-04-13 | Jake Westbrook | R | 34 | W 15-5 | @ ARI | 3 | 196 | W | 5.1 | 9 | 5 | 2 | 1 | 2 | 3 | 101 | 36 | 65 | 64% | 1-1 | 7.80 | 2.27 |
| 2011-04-14 | Jaime Garcia | L | 25 | W 9-5 | @ LAN | 3 | 32 | W | 5.0 | 8 | 3 | 2 | 0 | 2 | 2 | 94 | 36 | 58 | 62% | 2-0 | 1.35 | 1.05 |
| 2011-04-15 | Kyle Lohse | R | 33 | W 11-2 | @ LAN | 3 | 271 | W | 7.1 | 6 | 2 | 2 | 0 | 1 | 6 | 109 | 37 | 72 | 66% | 2-1 | 2.86 | 0.86 |
| 2011-04-16 | Kyle McClellan | R | 27 | W 9-2 | @ LAN | 3 | 3 | W | 7.0 | 6 | 1 | 1 | 0 | 0 | 2 | 93 | 31 | 62 | 67% | 2-0 | 1.89 | 1.26 |
| 2011-04-17 | Chris Carpenter | R | 36 | L 1-2 | @ LAN | 4 | 299 | - | 7.0 | 5 | 0 | 0 | 0 | 0 | 6 | 102 | 33 | 69 | 68% | 0-2 | 4.13 | 1.17 |
| 2011-04-20 | Jake Westbrook | R | 34 | W 6-8 | vs WAS | 4 | 197 | L | 3.0 | 7 | 7 | 7 | 0 | 2 | 1 | 68 | 28 | 40 | 59% | 1-2 | 10.00 | 2.39 |
| 2011-04-20 | Jaime Garcia | L | 25 | L 5-3 | vs WAS | 4 | 33 | W | 5.0 | 4 | 3 | 1 | 0 | 2 | 4 | 98 | 39 | 59 | 60% | 3-0 | 1.44 | 1.08 |
| 2011-04-21 | Kyle Lohse | R | 33 | L 5-0 | vs WAS | 4 | 272 | W | 9.0 | 2 | 0 | 0 | 0 | 2 | 6 | 110 | 39 | 71 | 65% | 3-1 | 2.03 | 0.74 |
| 2011-04-22 | Miguel Batista | R | 40 | L 4-2 | vs CIN | 1 | 239 | - | 0.0 | 0 | 0 | 0 | 0 | 1 | 0 | 4 | 4 | 0 | 0% | 1-0 | 1.29 | 1.57 |
| 2011-04-23 | Chris Carpenter | R | 36 | W 3-5 | vs CIN | 5 | 300 | - | 6.0 | 2 | 2 | 2 | 1 | 3 | 6 | 103 | 44 | 59 | 57% | 0-2 | 3.90 | 1.10 |
| 2011-04-24 | Jake Westbrook | R | 34 | L 3-0 | vs CIN | 5 | 198 | W | 6.0 | 3 | 0 | 0 | 0 | 3 | 4 | 87 | 39 | 48 | 55% | 2-2 | 7.50 | 2.04 |
| 2011-04-26 | Jaime Garcia | L | 25 | L 5-6 | @ HOU | 5 | 34 | - | 5.1 | 6 | 4 | 3 | 1 | 2 | 6 | 93 | 35 | 58 | 62% | 3-0 | 2.10 | 1.17 |
| 2011-04-27 | Kyle Lohse | R | 33 | W 6-5 | @ HOU | 5 | 273 | W | 7.0 | 4 | 0 | 0 | 0 | 1 | 2 | 97 | 31 | 66 | 68% | 4-1 | 1.66 | 0.74 |
| 2011-04-28 | Kyle McClellan | R | 27 | W 11-7 | @ HOU | 4 | 4 | W | 5.2 | 8 | 5 | 5 | 1 | 2 | 2 | 83 | 32 | 51 | 61% | 4-0 | 3.19 | 1.42 |
| 2011-04-29 | Chris Carpenter | R | 36 | W 5-3 | @ ATL | 6 | 301 | - | 7.0 | 10 | 3 | 3 | 2 | 2 | 3 | 108 | 48 | 60 | 56% | 0-2 | 3.89 | 1.22 |
| 2011-04-30 | Jake Westbrook | R | 34 | W 3-2 | @ ATL | 6 | 199 | - | 6.0 | 5 | 2 | 2 | 0 | 3 | 1 | 110 | 43 | 67 | 61% | 2-2 | 6.60 | 1.90 |
| 2011-05-01 | Jaime Garcia | L | 25 | L 5-6 | @ ATL | 6 | 35 | - | 6.0 | 5 | 4 | 3 | 1 | 1 | 6 | 97 | 38 | 59 | 61% | 3-0 | 2.50 | 1.14 |
| 2011-05-02 | Kyle Lohse | R | 33 | W 5-6 | vs FLO | 6 | 274 | - | 6.0 | 6 | 5 | 5 | 2 | 3 | 2 | 103 | 32 | 71 | 69% | 4-1 | 2.45 | 0.84 |
| 2011-05-03 | Kyle McClellan | R | 27 | L 7-5 | vs FLO | 5 | 5 | - | 5.0 | 6 | 4 | 4 | 0 | 2 | 2 | 75 | 32 | 43 | 57% | 4-0 | 3.75 | 1.44 |
| 2011-05-04 | Chris Carpenter | R | 36 | W 7-8 | vs FLO | 7 | 302 | - | 6.0 | 10 | 6 | 4 | 0 | 3 | 4 | 110 | 43 | 67 | 61% | 0-2 | 4.19 | 1.35 |
| 2011-05-05 | Jake Westbrook | R | 34 | L 6-3 | vs FLO | 7 | 200 | - | 6.1 | 7 | 3 | 3 | 0 | 0 | 8 | 98 | 28 | 70 | 71% | 2-2 | 6.08 | 1.73 |
| 2011-05-06 | Jaime Garcia | L | 25 | L 6-0 | vs MIL | 7 | 36 | W | 9.0 | 2 | 0 | 0 | 0 | 1 | 8 | 101 | 36 | 65 | 64% | 4-0 | 2.00 | 0.98 |
| 2011-05-07 | Kyle Lohse | R | 33 | W 0-4 | vs MIL | 7 | 275 | L | 8.0 | 6 | 1 | 1 | 0 | 2 | 3 | 105 | 35 | 70 | 67% | 4-2 | 2.25 | 0.87 |
| 2011-05-08 | Kyle McClellan | R | 27 | L 3-1 | vs MIL | 6 | 6 | W | 8.0 | 4 | 1 | 1 | 0 | 3 | 3 | 106 | 44 | 62 | 58% | 5-0 | 3.27 | 1.34 |
| 2011-05-10 | Chris Carpenter | R | 36 | W 6-4 | @ CHN | 8 | 303 | W | 7.0 | 13 | 4 | 4 | 0 | 2 | 4 | 116 | 37 | 79 | 68% | 1-2 | 4.32 | 1.46 |
| 2011-05-11 | Jake Westbrook | R | 34 | L 4-11 | @ CHN | 8 | 201 | L | 2.1 | 6 | 5 | 5 | 0 | 1 | 1 | 57 | 26 | 31 | 54% | 2-3 | 6.92 | 1.82 |
| 2011-05-12 | Jaime Garcia | L | 25 | W 9-1 | @ CHN | 8 | 37 | W | 7.0 | 9 | 1 | 1 | 0 | 1 | 4 | 84 | 23 | 61 | 73% | 5-0 | 1.90 | 1.04 |
| 2011-05-13 | Kyle Lohse | R | 33 | L 5-6 | @ CIN | 8 | 276 | - | 6.0 | 7 | 2 | 2 | 0 | 2 | 4 | 96 | 40 | 56 | 58% | 4-2 | 2.33 | 0.93 |
| 2011-05-14 | Kyle McClellan | R | 27 | L 3-7 | @ CIN | 7 | 7 | L | 6.0 | 7 | 4 | 4 | 3 | 3 | 1 | 93 | 35 | 58 | 62% | 5-1 | 3.60 | 1.38 |
| 2011-05-15 | Chris Carpenter | R | 36 | L 7-9 | @ CIN | 9 | 304 | L | 6.1 | 9 | 8 | 7 | 1 | 2 | 5 | 107 | 35 | 72 | 67% | 1-3 | 4.98 | 1.50 |
| 2011-05-16 | Jake Westbrook | R | 34 | L 3-1 | vs PHI | 9 | 202 | W | 7.0 | 4 | 1 | 1 | 0 | 3 | 1 | 109 | 45 | 64 | 59% | 3-3 | 6.07 | 1.70 |
| 2011-05-17 | Jaime Garcia | L | 25 | L 2-1 | vs PHI | 9 | 38 | - | 8.0 | 5 | 1 | 0 | 0 | 1 | 5 | 102 | 33 | 69 | 68% | 5-0 | 1.65 | 1.00 |
| 2011-05-18 | Kyle Lohse | R | 33 | L 5-1 | vs HOU | 9 | 277 | W | 8.0 | 6 | 1 | 1 | 0 | 1 | 3 | 102 | 32 | 70 | 69% | 5-2 | 2.18 | 0.92 |
| 2011-05-19 | Kyle McClellan | R | 27 | L 4-2 | vs HOU | 8 | 8 | W | 8.0 | 5 | 2 | 2 | 0 | 0 | 5 | 90 | 28 | 62 | 69% | 6-1 | 3.41 | 1.28 |
| 2011-05-20 | Chris Carpenter | R | 36 | L 0-3 | @ KCA | 10 | 305 | L | 6.1 | 9 | 3 | 3 | 0 | 0 | 5 | 87 | 23 | 64 | 74% | 1-4 | 4.86 | 1.48 |
| 2011-05-21 | Jake Westbrook | R | 34 | W 3-0 | @ KCA | 10 | 203 | W | 8.0 | 4 | 0 | 0 | 0 | 3 | 3 | 104 | 40 | 64 | 62% | 4-3 | 5.17 | 1.57 |
| 2011-05-22 | Jaime Garcia | L | 25 | W 9-8 | @ KCA | 10 | 39 | - | 5.0 | 7 | 3 | 3 | 1 | 0 | 4 | 83 | 26 | 57 | 69% | 5-0 | 1.94 | 1.03 |
| 2011-05-23 | Kyle Lohse | R | 33 | W 3-1 | @ SDN | 10 | 278 | W | 8.0 | 5 | 1 | 1 | 0 | 1 | 5 | 117 | 39 | 78 | 67% | 6-2 | 2.07 | 0.91 |
| 2011-05-24 | Kyle McClellan | R | 27 | W 3-2 | @ SDN | 9 | 9 | - | 6.0 | 2 | 2 | 0 | 1 | 0 | 4 | 74 | 23 | 51 | 69% | 6-1 | 3.09 | 1.19 |
| 2011-05-25 | Chris Carpenter | R | 36 | L 1-3 | @ SDN | 11 | 306 | L | 8.0 | 8 | 3 | 2 | 1 | 0 | 6 | 105 | 36 | 69 | 66% | 1-5 | 4.56 | 1.42 |
| 2011-05-27 | Jake Westbrook | R | 34 | W 10-3 | @ COL | 11 | 204 | W | 5.0 | 5 | 3 | 3 | 0 | 2 | 4 | 93 | 36 | 57 | 61% | 5-3 | 5.19 | 1.56 |
| 2011-05-28 | Jaime Garcia | L | 25 | L 4-15 | @ COL | 11 | 40 | L | 3.1 | 11 | 12 | 11 | 1 | 4 | 6 | 110 | 46 | 64 | 58% | 5-1 | 3.26 | 1.19 |
| 2011-05-29 | Kyle Lohse | R | 33 | W 4-3 | @ COL | 11 | 279 | W | 6.0 | 6 | 2 | 2 | 0 | 1 | 6 | 81 | 26 | 55 | 68% | 7-2 | 2.14 | 0.93 |
| 2011-05-30 | Kyle McClellan | R | 27 | W 3-7 | vs SFN | 10 | 10 | L | 4.0 | 7 | 7 | 7 | 2 | 2 | 2 | 75 | 30 | 45 | 60% | 6-2 | 3.84 | 1.25 |
| 2011-05-31 | Chris Carpenter | R | 36 | L 4-3 | vs SFN | 12 | 307 | - | 5.0 | 7 | 2 | 2 | 0 | 2 | 8 | 102 | 39 | 63 | 62% | 1-5 | 4.50 | 1.45 |
| 2011-06-01 | Jake Westbrook | R | 34 | W 5-7 | vs SFN | 12 | 205 | - | 5.2 | 9 | 3 | 3 | 0 | 2 | 4 | 99 | 37 | 62 | 63% | 5-3 | 5.12 | 1.58 |
| 2011-06-02 | Lance Lynn | R | 24 | W 7-12 | vs SFN | 1 | 1 | L | 5.1 | 4 | 5 | 5 | 1 | 0 | 5 | 63 | 22 | 41 | 65% | 0-1 | 9.00 | 0.80 |
| 2011-06-03 | Jaime Garcia | L | 25 | L 6-1 | vs CHN | 12 | 41 | W | 8.0 | 4 | 1 | 1 | 0 | 1 | 8 | 93 | 25 | 68 | 73% | 6-1 | 3.04 | 1.13 |
| 2011-06-04 | Kyle Lohse | R | 33 | L 5-4 | vs CHN | 12 | 280 | - | 5.2 | 11 | 4 | 4 | 1 | 0 | 5 | 88 | 23 | 65 | 74% | 7-2 | 2.41 | 0.99 |
| 2011-06-05 | Chris Carpenter | R | 36 | L 3-2 | vs CHN | 13 | 308 | - | 9.0 | 7 | 2 | 2 | 0 | 2 | 6 | 118 | 34 | 84 | 71% | 1-5 | 4.24 | 1.40 |
| 2011-06-07 | Jake Westbrook | R | 34 | W 7-4 | @ HOU | 13 | 206 | W | 5.1 | 8 | 3 | 2 | 1 | 3 | 3 | 99 | 37 | 62 | 63% | 6-3 | 5.01 | 1.63 |
| 2011-06-08 | Jaime Garcia | L | 25 | L 1-4 | @ HOU | 13 | 42 | L | 5.0 | 7 | 3 | 3 | 0 | 2 | 1 | 100 | 42 | 58 | 58% | 6-2 | 3.18 | 1.17 |
| 2011-06-09 | Lance Lynn | R | 24 | W 9-2 | @ HOU | 2 | 2 | W | 5.0 | 6 | 1 | 1 | 0 | 3 | 3 | 101 | 40 | 61 | 60% | 1-1 | 5.40 | 1.30 |
| 2011-06-10 | Kyle Lohse | R | 33 | L 0-8 | @ MIL | 13 | 281 | L | 5.0 | 5 | 4 | 4 | 1 | 3 | 1 | 81 | 35 | 46 | 57% | 7-3 | 2.67 | 1.02 |
| 2011-06-11 | Chris Carpenter | R | 36 | L 3-5 | @ MIL | 14 | 309 | L | 6.0 | 5 | 5 | 5 | 2 | 2 | 4 | 91 | 40 | 51 | 56% | 1-6 | 4.45 | 1.38 |
| 2011-06-12 | Jake Westbrook | R | 34 | L 3-4 | @ MIL | 14 | 207 | L | 5.0 | 8 | 4 | 4 | 1 | 1 | 0 | 78 | 31 | 47 | 60% | 6-4 | 5.16 | 1.64 |
| 2011-06-14 | Jaime Garcia | L | 25 | L 6-8 | @ WAS | 14 | 43 | - | 6.0 | 8 | 2 | 2 | 0 | 1 | 7 | 106 | 35 | 71 | 67% | 6-2 | 3.17 | 1.19 |
| 2011-06-15 | Kyle McClellan | R | 27 | L 0-10 | @ WAS | 11 | 11 | L | 5.0 | 7 | 5 | 3 | 1 | 0 | 3 | 77 | 26 | 51 | 66% | 6-3 | 3.95 | 1.26 |
| 2011-06-16 | Kyle Lohse | R | 33 | L 4-7 | @ WAS | 14 | 282 | - | 6.0 | 7 | 4 | 4 | 3 | 1 | 3 | 100 | 33 | 67 | 67% | 7-3 | 2.88 | 1.04 |
| 2011-06-17 | Chris Carpenter | R | 36 | W 4-5 | vs KCA | 15 | 310 | L | 8.0 | 10 | 5 | 4 | 0 | 1 | 7 | 122 | 41 | 81 | 66% | 1-7 | 4.45 | 1.38 |
| 2011-06-18 | Jake Westbrook | R | 34 | L 5-4 | vs KCA | 15 | 208 | - | 7.0 | 8 | 4 | 4 | 2 | 1 | 4 | 121 | 47 | 74 | 61% | 6-4 | 5.16 | 1.61 |
| 2011-06-19 | Jaime Garcia | L | 25 | L 5-4 | vs KCA | 15 | 44 | - | 5.1 | 7 | 3 | 2 | 0 | 1 | 5 | 90 | 31 | 59 | 66% | 6-2 | 3.19 | 1.22 |
| 2011-06-21 | Kyle McClellan | R | 27 | W 2-10 | vs PHI | 12 | 12 | - | 7.0 | 5 | 1 | 1 | 0 | 4 | 2 | 89 | 38 | 51 | 57% | 6-3 | 3.71 | 1.26 |
| 2011-06-22 | Kyle Lohse | R | 33 | W 0-4 | vs PHI | 15 | 283 | L | 8.0 | 7 | 3 | 3 | 2 | 0 | 0 | 90 | 34 | 56 | 62% | 7-4 | 2.91 | 1.03 |
| 2011-06-23 | Chris Carpenter | R | 36 | L 12-2 | vs PHI | 16 | 311 | W | 7.0 | 5 | 1 | 1 | 0 | 1 | 7 | 124 | 44 | 80 | 65% | 2-7 | 4.25 | 1.35 |
| 2011-06-24 | Jake Westbrook | R | 34 | W 4-5 | vs TOR | 16 | 209 | - | 4.1 | 10 | 4 | 4 | 0 | 1 | 3 | 99 | 39 | 60 | 61% | 6-4 | 5.34 | 1.66 |
| 2011-06-25 | Jaime Garcia | L | 25 | W 3-6 | vs TOR | 16 | 45 | L | 7.0 | 5 | 5 | 1 | 1 | 4 | 4 | 94 | 41 | 53 | 56% | 6-3 | 3.06 | 1.22 |
| 2011-06-26 | Kyle McClellan | R | 27 | W 0-5 | vs TOR | 13 | 13 | L | 5.1 | 8 | 5 | 5 | 1 | 3 | 4 | 92 | 35 | 57 | 62% | 6-4 | 4.02 | 1.32 |
| 2011-06-28 | Kyle Lohse | R | 33 | W 6-2 | @ BAL | 16 | 284 | W | 5.0 | 4 | 0 | 0 | 0 | 1 | 2 | 69 | 22 | 47 | 68% | 8-4 | 2.78 | 1.03 |
| 2011-06-29 | Chris Carpenter | R | 36 | W 5-1 | @ BAL | 17 | 312 | W | 9.0 | 7 | 1 | 1 | 0 | 1 | 5 | 132 | 41 | 91 | 69% | 3-7 | 3.99 | 1.31 |
| 2011-06-30 | Jaime Garcia | L | 25 | W 9-6 | @ BAL | 17 | 46 | W | 5.1 | 10 | 5 | 5 | 2 | 1 | 3 | 89 | 32 | 57 | 64% | 7-3 | 3.34 | 1.27 |
| 2011-07-01 | Jake Westbrook | R | 34 | W 5-3 | @ TBA | 17 | 210 | W | 7.0 | 2 | 0 | 0 | 0 | 3 | 7 | 112 | 43 | 69 | 62% | 7-4 | 4.94 | 1.59 |
| 2011-07-02 | Kyle McClellan | R | 27 | L 1-5 | @ TBA | 14 | 14 | L | 5.2 | 8 | 5 | 5 | 1 | 2 | 4 | 86 | 31 | 55 | 64% | 6-5 | 4.25 | 1.34 |
| 2011-07-03 | Kyle Lohse | R | 33 | L 3-8 | @ TBA | 17 | 285 | L | 5.1 | 7 | 4 | 4 | 0 | 0 | 2 | 82 | 27 | 55 | 67% | 8-5 | 2.97 | 1.04 |
| 2011-07-04 | Chris Carpenter | R | 36 | L 1-0 | vs CIN | 18 | 313 | W | 8.0 | 6 | 0 | 0 | 0 | 1 | 3 | 119 | 43 | 76 | 64% | 4-7 | 3.73 | 1.28 |
| 2011-07-05 | Jaime Garcia | L | 25 | L 8-1 | vs CIN | 18 | 47 | W | 6.0 | 2 | 1 | 1 | 0 | 3 | 4 | 93 | 40 | 53 | 57% | 8-3 | 3.24 | 1.24 |
| 2011-07-06 | Jake Westbrook | R | 34 | W 8-9 | vs CIN | 18 | 211 | - | 4.1 | 8 | 7 | 7 | 3 | 1 | 0 | 70 | 28 | 42 | 60% | 7-4 | 5.33 | 1.60 |
| 2011-07-07 | Kyle McClellan | R | 27 | W 1-4 | vs ARI | 15 | 15 | L | 7.0 | 6 | 4 | 3 | 1 | 2 | 1 | 96 | 41 | 55 | 57% | 6-6 | 4.22 | 1.33 |
| 2011-07-08 | Kyle Lohse | R | 33 | W 6-7 | vs ARI | 18 | 286 | L | 6.2 | 7 | 7 | 7 | 1 | 2 | 3 | 120 | 46 | 74 | 62% | 8-6 | 3.32 | 1.06 |
| 2011-07-09 | Chris Carpenter | R | 36 | L 7-6 | vs ARI | 19 | 314 | - | 6.0 | 9 | 5 | 4 | 0 | 4 | 3 | 100 | 38 | 62 | 62% | 4-7 | 3.84 | 1.33 |
| 2011-07-10 | Jaime Garcia | L | 25 | L 4-2 | vs ARI | 19 | 48 | W | 6.0 | 7 | 2 | 2 | 1 | 2 | 5 | 88 | 31 | 57 | 65% | 9-3 | 3.23 | 1.26 |
| 2011-07-15 | Jake Westbrook | R | 34 | L 5-6 | @ CIN | 19 | 212 | - | 5.0 | 5 | 2 | 2 | 2 | 0 | 5 | 78 | 31 | 47 | 60% | 7-4 | 5.24 | 1.57 |
| 2011-07-16 | Chris Carpenter | R | 36 | W 4-1 | @ CIN | 20 | 315 | W | 8.0 | 7 | 1 | 1 | 0 | 3 | 7 | 116 | 44 | 72 | 62% | 5-7 | 3.68 | 1.32 |
| 2011-07-17 | Jaime Garcia | L | 25 | L 1-3 | @ CIN | 20 | 49 | L | 7.0 | 6 | 2 | 1 | 0 | 0 | 6 | 106 | 37 | 69 | 65% | 9-4 | 3.12 | 1.23 |
| 2011-07-19 | Kyle Lohse | R | 33 | L 2-4 | @ NYN | 19 | 287 | L | 5.2 | 10 | 4 | 4 | 0 | 3 | 1 | 102 | 41 | 61 | 60% | 8-7 | 3.45 | 1.11 |
| 2011-07-20 | Kyle McClellan | R | 27 | L 5-6 | @ NYN | 16 | 16 | - | 6.0 | 6 | 4 | 4 | 1 | 2 | 2 | 95 | 42 | 53 | 56% | 6-6 | 4.33 | 1.33 |
| 2011-07-21 | Jake Westbrook | R | 34 | W 6-2 | @ NYN | 20 | 213 | W | 8.0 | 4 | 2 | 2 | 0 | 1 | 3 | 90 | 35 | 55 | 61% | 8-4 | 5.03 | 1.50 |
| 2011-07-22 | Chris Carpenter | R | 36 | W 6-4 | @ PIT | 21 | 316 | W | 8.0 | 10 | 4 | 4 | 0 | 1 | 4 | 107 | 41 | 66 | 62% | 6-7 | 3.72 | 1.32 |
| 2011-07-23 | Jaime Garcia | L | 25 | W 9-1 | @ PIT | 21 | 50 | W | 7.1 | 8 | 1 | 1 | 0 | 1 | 5 | 95 | 34 | 61 | 64% | 10-4 | 3.00 | 1.23 |
| 2011-07-24 | Kyle Lohse | R | 33 | L 3-4 | @ PIT | 20 | 288 | - | 5.0 | 4 | 2 | 2 | 0 | 0 | 4 | 68 | 21 | 47 | 69% | 8-7 | 3.45 | 1.10 |
| 2011-07-25 | Kyle McClellan | R | 27 | L 10-5 | vs HOU | 17 | 17 | W | 7.0 | 6 | 1 | 1 | 0 | 0 | 5 | 90 | 33 | 57 | 63% | 7-6 | 4.14 | 1.30 |
| 2011-07-26 | Jake Westbrook | R | 34 | L 3-1 | vs HOU | 21 | 214 | W | 6.0 | 7 | 1 | 1 | 0 | 1 | 3 | 97 | 38 | 59 | 61% | 9-4 | 4.85 | 1.50 |
| 2011-07-27 | Chris Carpenter | R | 36 | W 2-4 | vs HOU | 22 | 317 | - | 7.0 | 8 | 2 | 2 | 1 | 1 | 8 | 101 | 30 | 71 | 70% | 6-7 | 3.67 | 1.32 |
| 2011-07-28 | Jaime Garcia | L | 25 | W 3-5 | vs HOU | 22 | 51 | L | 6.0 | 8 | 5 | 4 | 1 | 2 | 3 | 96 | 34 | 62 | 65% | 10-5 | 3.13 | 1.25 |
| 2011-07-29 | Edwin Jackson | R | 28 | L 9-2 | vs CHN | 20 | 162 | W | 7.0 | 7 | 1 | 1 | 0 | 2 | 4 | 95 | 29 | 66 | 69% | 8-7 | 3.77 | 1.41 |
| 2011-07-30 | Kyle Lohse | R | 33 | L 13-5 | vs CHN | 21 | 289 | W | 5.0 | 2 | 5 | 0 | 1 | 2 | 3 | 69 | 24 | 45 | 65% | 9-7 | 3.33 | 1.09 |
| 2011-07-31 | Jake Westbrook | R | 34 | W 3-6 | vs CHN | 22 | 215 | L | 6.0 | 3 | 4 | 4 | 0 | 3 | 3 | 77 | 31 | 46 | 60% | 9-5 | 4.90 | 1.47 |
| 2011-08-01 | Chris Carpenter | R | 36 | L 2-6 | @ MIL | 23 | 318 | L | 5.0 | 7 | 5 | 5 | 0 | 2 | 6 | 97 | 38 | 59 | 61% | 6-8 | 3.84 | 1.34 |
| 2011-08-02 | Jaime Garcia | L | 25 | W 8-7 | @ MIL | 23 | 52 | - | 5.0 | 10 | 7 | 3 | 1 | 0 | 6 | 84 | 24 | 60 | 71% | 10-5 | 3.21 | 1.27 |
| 2011-08-03 | Edwin Jackson | R | 28 | L 5-10 | @ MIL | 21 | 163 | L | 7.0 | 14 | 10 | 8 | 4 | 1 | 6 | 120 | 43 | 77 | 64% | 8-8 | 4.10 | 1.45 |
| 2011-08-04 | Kyle Lohse | R | 33 | W 7-4 | @ FLO | 22 | 290 | - | 3.0 | 7 | 3 | 3 | 0 | 3 | 1 | 74 | 33 | 41 | 55% | 9-7 | 3.45 | 1.13 |
| 2011-08-05 | Jake Westbrook | R | 34 | W 3-2 | @ FLO | 23 | 216 | - | 6.0 | 6 | 2 | 2 | 0 | 3 | 4 | 110 | 44 | 66 | 60% | 9-5 | 4.81 | 1.47 |
| 2011-08-06 | Chris Carpenter | R | 36 | W 2-1 | @ FLO | 24 | 319 | W | 6.2 | 5 | 1 | 1 | 0 | 2 | 7 | 118 | 40 | 78 | 66% | 7-8 | 3.75 | 1.33 |
| 2011-08-07 | Jaime Garcia | L | 25 | W 8-4 | @ FLO | 24 | 53 | - | 5.0 | 6 | 2 | 2 | 0 | 3 | 5 | 99 | 48 | 51 | 52% | 10-5 | 3.22 | 1.29 |
| 2011-08-09 | Edwin Jackson | R | 28 | W 3-5 | vs MIL | 22 | 164 | - | 6.0 | 6 | 3 | 2 | 1 | 2 | 2 | 97 | 37 | 60 | 62% | 8-8 | 4.06 | 1.44 |
| 2011-08-10 | Jake Westbrook | R | 34 | W 1-5 | vs MIL | 24 | 217 | L | 8.0 | 6 | 3 | 3 | 0 | 5 | 4 | 116 | 48 | 68 | 59% | 9-6 | 4.73 | 1.47 |
| 2011-08-11 | Chris Carpenter | R | 36 | L 5-2 | vs MIL | 25 | 320 | W | 8.0 | 10 | 2 | 2 | 0 | 3 | 4 | 119 | 45 | 74 | 62% | 8-8 | 3.68 | 1.35 |
| 2011-08-12 | Kyle Lohse | R | 33 | L 6-1 | vs COL | 23 | 291 | W | 6.1 | 4 | 1 | 1 | 1 | 3 | 3 | 89 | 31 | 58 | 65% | 10-7 | 3.37 | 1.14 |
| 2011-08-13 | Jaime Garcia | L | 25 | W 1-6 | vs COL | 25 | 54 | L | 5.0 | 6 | 5 | 5 | 1 | 4 | 3 | 83 | 35 | 48 | 58% | 10-6 | 3.41 | 1.31 |
| 2011-08-14 | Edwin Jackson | R | 28 | L 6-2 | vs COL | 23 | 165 | W | 5.1 | 8 | 2 | 2 | 1 | 3 | 4 | 95 | 39 | 56 | 59% | 9-8 | 4.04 | 1.47 |
| 2011-08-15 | Jake Westbrook | R | 34 | L 2-6 | @ PIT | 25 | 218 | L | 5.2 | 9 | 5 | 4 | 2 | 1 | 3 | 110 | 37 | 73 | 66% | 9-7 | 4.82 | 1.49 |
| 2011-08-16 | Chris Carpenter | R | 36 | L 4-5 | @ PIT | 26 | 321 | - | 7.0 | 5 | 3 | 3 | 1 | 1 | 10 | 98 | 32 | 66 | 67% | 8-8 | 3.69 | 1.33 |
| 2011-08-17 | Kyle Lohse | R | 33 | W 7-2 | @ PIT | 24 | 292 | W | 7.0 | 5 | 2 | 2 | 1 | 1 | 7 | 100 | 30 | 70 | 70% | 11-7 | 3.33 | 1.12 |
| 2011-08-19 | Jaime Garcia | L | 25 | L 4-5 | @ CHN | 26 | 55 | - | 6.1 | 9 | 3 | 3 | 1 | 2 | 1 | 92 | 30 | 62 | 67% | 10-6 | 3.45 | 1.33 |
| 2011-08-20 | Edwin Jackson | R | 28 | L 0-3 | @ CHN | 24 | 166 | L | 7.0 | 5 | 3 | 3 | 1 | 1 | 6 | 97 | 31 | 66 | 68% | 9-9 | 4.03 | 1.44 |
| 2011-08-21 | Jake Westbrook | R | 34 | W 6-2 | @ CHN | 26 | 219 | W | 7.0 | 7 | 2 | 2 | 0 | 2 | 3 | 100 | 39 | 61 | 61% | 10-7 | 4.71 | 1.48 |
| 2011-08-22 | Chris Carpenter | R | 36 | W 1-2 | vs LAN | 27 | 322 | - | 8.0 | 5 | 1 | 1 | 0 | 1 | 7 | 99 | 30 | 69 | 70% | 8-8 | 3.58 | 1.30 |
| 2011-08-23 | Kyle Lohse | R | 33 | W 2-13 | vs LAN | 25 | 293 | L | 3.0 | 8 | 8 | 8 | 2 | 1 | 3 | 63 | 21 | 42 | 67% | 11-8 | 3.73 | 1.16 |
| 2011-08-24 | Jaime Garcia | L | 25 | W 4-9 | vs LAN | 27 | 56 | L | 5.0 | 9 | 7 | 7 | 1 | 2 | 3 | 97 | 38 | 59 | 61% | 10-7 | 3.73 | 1.36 |
| 2011-08-25 | Edwin Jackson | R | 28 | L 8-4 | vs PIT | 25 | 167 | W | 6.0 | 6 | 4 | 1 | 0 | 3 | 2 | 105 | 41 | 64 | 61% | 10-9 | 3.94 | 1.44 |
| 2011-08-26 | Jake Westbrook | R | 34 | L 5-4 | vs PIT | 27 | 220 | - | 6.0 | 7 | 4 | 4 | 0 | 5 | 3 | 110 | 49 | 61 | 55% | 10-7 | 4.76 | 1.50 |
| 2011-08-27 | Chris Carpenter | R | 36 | W 0-7 | vs PIT | 28 | 323 | L | 5.0 | 9 | 6 | 6 | 1 | 2 | 5 | 85 | 30 | 55 | 65% | 8-9 | 3.77 | 1.32 |
| 2011-08-28 | Kyle Lohse | R | 33 | L 7-4 | vs PIT | 26 | 294 | W | 5.0 | 6 | 4 | 2 | 0 | 2 | 4 | 99 | 38 | 61 | 62% | 12-8 | 3.72 | 1.17 |
| 2011-08-30 | Edwin Jackson | R | 28 | W 2-1 | @ MIL | 26 | 168 | W | 7.0 | 6 | 1 | 1 | 0 | 0 | 3 | 94 | 27 | 67 | 71% | 11-9 | 3.83 | 1.42 |
| 2011-08-31 | Jake Westbrook | R | 34 | W 8-3 | @ MIL | 28 | 221 | W | 5.0 | 8 | 3 | 2 | 1 | 0 | 1 | 68 | 22 | 46 | 68% | 11-7 | 4.73 | 1.50 |
| 2011-09-01 | Brandon Dickson | R | 27 | W 8-4 | @ MIL | 1 | 1 | - | 3.1 | 6 | 3 | 3 | 2 | 1 | 3 | 53 | 17 | 36 | 68% | 0-0 | 3.86 | 1.57 |
| 2011-09-02 | Chris Carpenter | R | 36 | W 8-11 | vs CIN | 29 | 324 | - | 6.0 | 8 | 6 | 6 | 1 | 1 | 5 | 102 | 30 | 72 | 71% | 8-9 | 3.93 | 1.33 |
| 2011-09-03 | Jaime Garcia | L | 25 | L 6-4 | vs CIN | 28 | 57 | W | 6.0 | 7 | 2 | 1 | 0 | 1 | 6 | 95 | 33 | 62 | 65% | 11-7 | 3.65 | 1.36 |
| 2011-09-04 | Edwin Jackson | R | 28 | W 2-3 | vs CIN | 27 | 169 | - | 7.0 | 8 | 2 | 2 | 1 | 2 | 8 | 110 | 43 | 67 | 61% | 11-9 | 3.78 | 1.42 |
| 2011-09-05 | Jake Westbrook | R | 34 | W 1-4 | vs MIL | 29 | 222 | L | 6.0 | 9 | 3 | 2 | 1 | 1 | 9 | 107 | 38 | 69 | 64% | 11-8 | 4.66 | 1.51 |
| 2011-09-06 | Kyle Lohse | R | 33 | L 4-2 | vs MIL | 27 | 295 | W | 6.0 | 4 | 0 | 0 | 0 | 3 | 6 | 91 | 26 | 65 | 71% | 13-8 | 3.59 | 1.17 |
| 2011-09-07 | Chris Carpenter | R | 36 | L 2-0 | vs MIL | 30 | 325 | W | 9.0 | 4 | 0 | 0 | 0 | 2 | 5 | 97 | 33 | 64 | 66% | 9-9 | 3.76 | 1.30 |
| 2011-09-09 | Edwin Jackson | R | 28 | L 4-3 | vs ATL | 28 | 170 | - | 6.0 | 7 | 2 | 2 | 0 | 2 | 5 | 98 | 35 | 63 | 64% | 11-9 | 3.75 | 1.42 |
| 2011-09-10 | Jaime Garcia | L | 25 | L 4-3 | vs ATL | 29 | 58 | W | 6.0 | 8 | 3 | 3 | 1 | 0 | 4 | 73 | 21 | 52 | 71% | 12-7 | 3.68 | 1.36 |
| 2011-09-11 | Jake Westbrook | R | 34 | L 6-3 | vs ATL | 30 | 223 | W | 5.1 | 5 | 2 | 2 | 0 | 1 | 4 | 89 | 29 | 60 | 67% | 12-8 | 4.60 | 1.49 |
| 2011-09-12 | Kyle Lohse | R | 33 | L 5-6 | @ PIT | 28 | 296 | - | 6.0 | 8 | 3 | 3 | 0 | 1 | 3 | 99 | 36 | 63 | 64% | 13-8 | 3.62 | 1.18 |
| 2011-09-13 | Chris Carpenter | R | 36 | W 6-4 | @ PIT | 31 | 326 | - | 7.0 | 10 | 4 | 4 | 2 | 1 | 6 | 117 | 34 | 83 | 71% | 9-9 | 3.80 | 1.31 |
| 2011-09-14 | Edwin Jackson | R | 28 | W 3-2 | @ PIT | 29 | 171 | W | 6.2 | 8 | 2 | 2 | 0 | 0 | 5 | 100 | 33 | 67 | 67% | 12-9 | 3.71 | 1.41 |
| 2011-09-16 | Jaime Garcia | L | 25 | W 4-2 | @ PHI | 30 | 59 | - | 7.0 | 5 | 1 | 1 | 0 | 2 | 4 | 106 | 36 | 70 | 66% | 12-7 | 3.59 | 1.34 |
| 2011-09-17 | Jake Westbrook | R | 34 | L 2-9 | @ PHI | 31 | 224 | L | 3.1 | 5 | 2 | 1 | 0 | 5 | 1 | 71 | 34 | 37 | 52% | 12-9 | 4.58 | 1.52 |
| 2011-09-18 | Chris Carpenter | R | 36 | W 5-0 | @ PHI | 32 | 327 | W | 8.0 | 8 | 0 | 0 | 0 | 1 | 5 | 115 | 43 | 72 | 63% | 10-9 | 3.67 | 1.30 |
| 2011-09-19 | Kyle Lohse | R | 33 | W 4-3 | @ PHI | 29 | 297 | W | 7.1 | 7 | 1 | 0 | 0 | 1 | 5 | 111 | 40 | 71 | 64% | 14-8 | 3.48 | 1.18 |
| 2011-09-20 | Edwin Jackson | R | 28 | L 11-6 | vs NYN | 30 | 172 | - | 5.0 | 9 | 5 | 5 | 0 | 4 | 4 | 94 | 40 | 54 | 57% | 12-9 | 3.84 | 1.44 |
| 2011-09-21 | Jaime Garcia | L | 25 | L 6-5 | vs NYN | 31 | 60 | W | 7.2 | 6 | 4 | 0 | 0 | 0 | 5 | 90 | 34 | 56 | 62% | 13-7 | 3.44 | 1.32 |
| 2011-09-22 | Jake Westbrook | R | 34 | W 6-8 | vs NYN | 32 | 225 | - | 6.0 | 3 | 1 | 1 | 0 | 4 | 4 | 81 | 31 | 50 | 62% | 12-9 | 4.48 | 1.51 |
| 2011-09-23 | Chris Carpenter | R | 36 | W 1-5 | vs CHN | 33 | 328 | - | 7.0 | 5 | 1 | 1 | 0 | 2 | 5 | 93 | 31 | 62 | 67% | 10-9 | 3.59 | 1.29 |
| 2011-09-24 | Kyle Lohse | R | 33 | L 2-1 | vs CHN | 30 | 298 | - | 7.0 | 6 | 1 | 1 | 0 | 0 | 8 | 94 | 24 | 70 | 74% | 14-8 | 3.40 | 1.17 |
| 2011-09-25 | Edwin Jackson | R | 28 | L 3-2 | vs CHN | 31 | 173 | - | 7.0 | 5 | 2 | 2 | 0 | 3 | 2 | 107 | 42 | 65 | 61% | 12-9 | 3.80 | 1.43 |
| 2011-09-26 | Jaime Garcia | L | 25 | L 4-5 | @ HOU | 32 | 61 | - | 4.0 | 4 | 4 | 4 | 1 | 1 | 5 | 66 | 23 | 43 | 65% | 13-7 | 3.55 | 1.32 |
| 2011-09-27 | Jake Westbrook | R | 34 | W 13-6 | @ HOU | 33 | 226 | - | 2.1 | 7 | 5 | 5 | 0 | 1 | 2 | 45 | 16 | 29 | 64% | 12-9 | 4.67 | 1.54 |
| 2011-09-28 | Chris Carpenter | R | 36 | W 8-0 | @ HOU | 34 | 329 | W | 9.0 | 2 | 0 | 0 | 0 | 1 | 11 | 104 | 31 | 73 | 70% | 11-9 | 3.46 | 1.26 |