| Central | W | L | Pct | GB |
| Minnesota | 87 | 76 | .534 | -- |
| Detroit | 86 | 77 | .528 | 1.0 |
| Chi White Sox | 79 | 83 | .488 | 7.5 |
| Cleveland | 65 | 97 | .401 | 21.5 |
| KC Royals | 65 | 97 | .401 | 21.5 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2009-04-07 | Mark Buehrle | L | 30 | L 4-2 | vs KCA | 1 | 269 | - | 5.0 | 6 | 2 | 2 | 1 | 3 | 3 | 95 | 39 | 56 | 59% | 0-0 | 3.60 | 1.80 |
| 2009-04-08 | Gavin Floyd | R | 26 | W 0-2 | vs KCA | 1 | 63 | L | 7.0 | 6 | 2 | 2 | 0 | 2 | 9 | 96 | 40 | 56 | 58% | 0-1 | 2.57 | 1.14 |
| 2009-04-09 | John Danks | L | 24 | W 1-2 | vs KCA | 1 | 60 | - | 6.0 | 3 | 0 | 0 | 0 | 3 | 5 | 95 | 40 | 55 | 58% | 0-0 | 0.00 | 1.00 |
| 2009-04-10 | Jose Contreras | R | 37 | W 5-12 | vs MIN | 1 | 153 | L | 5.0 | 7 | 4 | 4 | 1 | 3 | 3 | 84 | 35 | 49 | 58% | 0-1 | 7.20 | 2.00 |
| 2009-04-11 | Bartolo Colon | R | 34 | L 8-0 | vs MIN | 1 | 314 | W | 6.0 | 3 | 0 | 0 | 0 | 2 | 2 | 92 | 34 | 58 | 63% | 1-0 | 0.00 | 0.83 |
| 2009-04-12 | Mark Buehrle | L | 30 | L 6-1 | vs MIN | 2 | 270 | W | 6.1 | 2 | 1 | 1 | 1 | 0 | 5 | 95 | 34 | 61 | 64% | 1-0 | 2.45 | 1.00 |
| 2009-04-13 | Gavin Floyd | R | 26 | W 10-6 | @ DET | 2 | 64 | W | 5.0 | 5 | 6 | 6 | 1 | 7 | 2 | 101 | 51 | 50 | 50% | 1-1 | 6.00 | 1.67 |
| 2009-04-15 | Jose Contreras | R | 37 | L 0-9 | @ DET | 2 | 154 | L | 5.1 | 5 | 5 | 4 | 1 | 2 | 4 | 99 | 40 | 59 | 60% | 0-2 | 7.20 | 1.70 |
| 2009-04-16 | John Danks | L | 24 | W 3-2 | @ TBA | 2 | 61 | W | 6.0 | 2 | 1 | 1 | 1 | 4 | 8 | 101 | 42 | 59 | 58% | 1-0 | 0.75 | 1.00 |
| 2009-04-17 | Bartolo Colon | R | 34 | L 5-6 | @ TBA | 2 | 315 | - | 5.2 | 6 | 5 | 5 | 1 | 1 | 4 | 91 | 37 | 54 | 59% | 1-0 | 3.75 | 1.00 |
| 2009-04-18 | Mark Buehrle | L | 30 | W 8-3 | @ TBA | 3 | 271 | W | 6.2 | 8 | 3 | 3 | 0 | 3 | 5 | 104 | 38 | 66 | 63% | 2-0 | 3.00 | 1.22 |
| 2009-04-19 | Gavin Floyd | R | 26 | W 12-2 | @ TBA | 3 | 65 | W | 7.0 | 6 | 2 | 2 | 1 | 0 | 7 | 94 | 33 | 61 | 65% | 2-1 | 4.74 | 1.37 |
| 2009-04-21 | Jose Contreras | R | 37 | L 3-10 | @ BAL | 3 | 155 | L | 5.1 | 7 | 6 | 6 | 1 | 6 | 2 | 105 | 45 | 60 | 57% | 0-3 | 7.88 | 1.88 |
| 2009-04-22 | John Danks | L | 24 | W 8-2 | @ BAL | 3 | 62 | W | 7.0 | 4 | 1 | 1 | 1 | 0 | 3 | 107 | 34 | 73 | 68% | 2-0 | 0.95 | 0.84 |
| 2009-04-23 | Bartolo Colon | R | 34 | L 2-6 | @ BAL | 3 | 316 | L | 3.0 | 8 | 5 | 5 | 0 | 2 | 0 | 63 | 24 | 39 | 62% | 1-1 | 6.00 | 1.47 |
| 2009-04-24 | Gavin Floyd | R | 26 | W 0-14 | vs TOR | 4 | 66 | L | 4.1 | 9 | 6 | 5 | 0 | 5 | 5 | 93 | 38 | 55 | 59% | 2-2 | 5.87 | 1.74 |
| 2009-04-25 | Mark Buehrle | L | 30 | L 10-2 | vs TOR | 4 | 272 | W | 6.0 | 6 | 2 | 2 | 0 | 3 | 4 | 92 | 39 | 53 | 58% | 3-0 | 3.00 | 1.29 |
| 2009-04-26 | Jose Contreras | R | 37 | W 3-4 | vs TOR | 4 | 156 | - | 7.0 | 8 | 3 | 3 | 0 | 1 | 2 | 96 | 33 | 63 | 66% | 0-3 | 6.65 | 1.70 |
| 2009-04-28 | Bartolo Colon | R | 34 | L 2-1 | vs SEA | 4 | 317 | W | 7.0 | 4 | 1 | 0 | 0 | 1 | 6 | 95 | 30 | 65 | 68% | 2-1 | 4.09 | 1.23 |
| 2009-04-28 | John Danks | L | 24 | W 1-9 | vs SEA | 4 | 63 | L | 4.0 | 8 | 5 | 5 | 1 | 1 | 2 | 74 | 27 | 47 | 64% | 2-1 | 2.74 | 1.09 |
| 2009-04-29 | Gavin Floyd | R | 26 | L 6-3 | vs SEA | 5 | 67 | - | 6.0 | 10 | 3 | 3 | 0 | 2 | 3 | 108 | 40 | 68 | 63% | 2-2 | 5.59 | 1.79 |
| 2009-05-01 | Mark Buehrle | L | 30 | W 4-3 | @ TEX | 5 | 273 | W | 6.0 | 7 | 3 | 3 | 1 | 0 | 2 | 79 | 28 | 51 | 65% | 4-0 | 3.30 | 1.27 |
| 2009-05-02 | Jose Contreras | R | 37 | L 6-9 | @ TEX | 5 | 157 | L | 3.1 | 7 | 7 | 7 | 1 | 2 | 3 | 63 | 26 | 37 | 59% | 0-4 | 8.31 | 1.85 |
| 2009-05-03 | John Danks | L | 24 | L 1-5 | @ TEX | 5 | 64 | L | 5.1 | 10 | 5 | 5 | 1 | 1 | 3 | 106 | 38 | 68 | 64% | 2-2 | 3.86 | 1.29 |
| 2009-05-04 | Bartolo Colon | R | 34 | L 0-3 | @ KCA | 5 | 318 | L | 5.0 | 7 | 3 | 2 | 1 | 3 | 7 | 98 | 40 | 58 | 59% | 2-2 | 4.00 | 1.37 |
| 2009-05-05 | Gavin Floyd | R | 26 | L 7-8 | @ KCA | 6 | 68 | - | 5.0 | 6 | 6 | 6 | 2 | 2 | 2 | 86 | 39 | 47 | 55% | 2-2 | 6.35 | 1.76 |
| 2009-05-07 | Mark Buehrle | L | 30 | L 6-0 | vs DET | 6 | 274 | W | 8.0 | 1 | 0 | 0 | 0 | 2 | 5 | 109 | 42 | 67 | 61% | 5-0 | 2.61 | 1.08 |
| 2009-05-08 | Jose Contreras | R | 37 | W 0-6 | vs TEX | 6 | 158 | L | 3.2 | 6 | 5 | 3 | 0 | 2 | 3 | 81 | 34 | 47 | 58% | 0-5 | 8.10 | 1.87 |
| 2009-05-09 | John Danks | L | 24 | L 3-2 | vs TEX | 6 | 65 | - | 6.0 | 4 | 1 | 1 | 0 | 1 | 10 | 96 | 31 | 65 | 68% | 2-2 | 3.44 | 1.21 |
| 2009-05-10 | Bartolo Colon | R | 34 | W 1-7 | vs TEX | 6 | 319 | L | 4.2 | 5 | 5 | 5 | 2 | 3 | 4 | 93 | 41 | 52 | 56% | 2-3 | 4.94 | 1.45 |
| 2009-05-11 | Gavin Floyd | R | 26 | L 4-9 | @ CLE | 7 | 69 | L | 5.0 | 11 | 8 | 8 | 0 | 3 | 3 | 109 | 51 | 58 | 53% | 2-3 | 7.38 | 1.90 |
| 2009-05-12 | Clayton Richard | L | 26 | W 7-4 | @ CLE | 1 | 9 | - | 3.1 | 6 | 4 | 4 | 0 | 3 | 2 | 83 | 40 | 43 | 52% | 0-0 | 5.40 | 1.85 |
| 2009-05-13 | Mark Buehrle | L | 30 | L 0-4 | @ CLE | 7 | 275 | L | 7.0 | 7 | 4 | 4 | 2 | 1 | 6 | 98 | 30 | 68 | 69% | 5-1 | 3.00 | 1.09 |
| 2009-05-15 | John Danks | L | 24 | L 3-8 | @ TOR | 7 | 66 | L | 3.0 | 9 | 7 | 7 | 1 | 1 | 3 | 62 | 22 | 40 | 65% | 2-3 | 4.86 | 1.38 |
| 2009-05-16 | Bartolo Colon | R | 34 | L 1-2 | @ TOR | 7 | 320 | - | 5.0 | 5 | 0 | 0 | 0 | 2 | 2 | 62 | 26 | 36 | 58% | 2-3 | 4.25 | 1.44 |
| 2009-05-17 | Gavin Floyd | R | 26 | L 2-8 | @ TOR | 8 | 70 | L | 5.0 | 7 | 6 | 6 | 2 | 2 | 4 | 76 | 29 | 47 | 62% | 2-4 | 7.77 | 1.89 |
| 2009-05-18 | Clayton Richard | L | 26 | L 2-3 | @ TOR | 2 | 10 | - | 7.0 | 3 | 2 | 1 | 1 | 3 | 3 | 95 | 43 | 52 | 55% | 0-0 | 4.33 | 1.59 |
| 2009-05-19 | Mark Buehrle | L | 30 | L 6-2 | vs MIN | 8 | 276 | W | 7.0 | 8 | 2 | 1 | 1 | 0 | 3 | 100 | 39 | 61 | 61% | 6-1 | 2.77 | 1.10 |
| 2009-05-20 | John Danks | L | 24 | L 7-4 | vs MIN | 8 | 67 | W | 5.2 | 5 | 4 | 2 | 1 | 3 | 7 | 108 | 41 | 67 | 62% | 3-3 | 4.60 | 1.37 |
| 2009-05-21 | Bartolo Colon | R | 34 | W 1-20 | vs MIN | 8 | 321 | L | 2.0 | 7 | 8 | 1 | 2 | 2 | 1 | 61 | 26 | 35 | 57% | 2-4 | 4.26 | 1.61 |
| 2009-05-22 | Gavin Floyd | R | 26 | L 2-0 | vs PIT | 9 | 71 | W | 8.0 | 2 | 0 | 0 | 0 | 2 | 8 | 103 | 37 | 66 | 64% | 3-4 | 6.58 | 1.67 |
| 2009-05-23 | Clayton Richard | L | 26 | L 4-0 | vs PIT | 3 | 11 | W | 6.0 | 4 | 0 | 0 | 0 | 3 | 8 | 106 | 44 | 62 | 58% | 1-0 | 3.55 | 1.52 |
| 2009-05-24 | Mark Buehrle | L | 30 | W 3-4 | vs PIT | 9 | 277 | - | 7.0 | 12 | 1 | 1 | 0 | 0 | 3 | 106 | 38 | 68 | 64% | 6-1 | 2.59 | 1.17 |
| 2009-05-25 | John Danks | L | 24 | W 17-3 | @ ANA | 9 | 68 | W | 6.0 | 4 | 3 | 3 | 0 | 6 | 4 | 113 | 55 | 58 | 51% | 4-3 | 4.59 | 1.41 |
| 2009-05-26 | Bartolo Colon | R | 34 | W 4-2 | @ ANA | 9 | 322 | W | 6.2 | 4 | 1 | 1 | 1 | 0 | 3 | 85 | 33 | 52 | 61% | 3-4 | 3.80 | 1.44 |
| 2009-05-27 | Gavin Floyd | R | 26 | L 1-3 | @ ANA | 10 | 72 | L | 8.0 | 7 | 3 | 3 | 0 | 2 | 8 | 100 | 31 | 69 | 69% | 3-5 | 6.15 | 1.60 |
| 2009-05-29 | Clayton Richard | L | 26 | W 11-2 | @ KCA | 4 | 12 | W | 7.0 | 5 | 2 | 2 | 1 | 1 | 7 | 92 | 30 | 62 | 67% | 2-0 | 3.38 | 1.40 |
| 2009-05-30 | Mark Buehrle | L | 30 | W 5-3 | @ KCA | 10 | 278 | - | 7.1 | 7 | 3 | 3 | 1 | 0 | 6 | 95 | 28 | 67 | 71% | 6-1 | 2.73 | 1.15 |
| 2009-05-31 | John Danks | L | 24 | W 7-4 | @ KCA | 10 | 69 | - | 5.1 | 9 | 4 | 4 | 0 | 2 | 5 | 99 | 33 | 66 | 67% | 4-3 | 4.83 | 1.48 |
| 2009-06-01 | Gavin Floyd | R | 26 | L 6-2 | vs OAK | 11 | 73 | - | 7.0 | 4 | 2 | 2 | 1 | 3 | 8 | 107 | 42 | 65 | 61% | 3-5 | 5.78 | 1.54 |
| 2009-06-02 | Bartolo Colon | R | 34 | W 0-5 | vs OAK | 10 | 323 | L | 5.1 | 6 | 5 | 2 | 1 | 3 | 4 | 81 | 31 | 50 | 62% | 3-5 | 3.78 | 1.48 |
| 2009-06-03 | Clayton Richard | L | 26 | W 3-5 | vs OAK | 5 | 13 | L | 5.1 | 7 | 5 | 5 | 3 | 4 | 4 | 90 | 38 | 52 | 58% | 2-1 | 4.00 | 1.49 |
| 2009-06-04 | Mark Buehrle | L | 30 | W 0-7 | vs OAK | 11 | 279 | L | 8.0 | 5 | 4 | 4 | 1 | 3 | 4 | 99 | 39 | 60 | 61% | 6-2 | 2.92 | 1.14 |
| 2009-06-05 | John Danks | L | 24 | W 0-6 | vs CLE | 11 | 70 | L | 5.2 | 6 | 5 | 5 | 3 | 2 | 4 | 100 | 41 | 59 | 59% | 4-4 | 5.10 | 1.47 |
| 2009-06-06 | Gavin Floyd | R | 26 | L 4-2 | vs CLE | 12 | 74 | W | 6.2 | 5 | 2 | 1 | 0 | 1 | 7 | 105 | 36 | 69 | 66% | 4-5 | 5.35 | 1.47 |
| 2009-06-07 | Bartolo Colon | R | 34 | W 4-8 | vs CLE | 11 | 324 | L | 5.0 | 8 | 6 | 5 | 4 | 1 | 3 | 88 | 33 | 55 | 63% | 3-6 | 4.25 | 1.51 |
| 2009-06-08 | Clayton Richard | L | 26 | W 4-5 | vs DET | 6 | 14 | - | 4.2 | 5 | 3 | 3 | 0 | 5 | 4 | 100 | 43 | 57 | 57% | 2-1 | 4.14 | 1.54 |
| 2009-06-08 | Jose Contreras | R | 38 | L 6-1 | vs DET | 7 | 159 | W | 8.0 | 1 | 0 | 0 | 0 | 1 | 3 | 114 | 46 | 68 | 60% | 1-5 | 6.39 | 1.53 |
| 2009-06-09 | Mark Buehrle | L | 30 | W 6-7 | vs DET | 12 | 280 | - | 6.1 | 4 | 5 | 5 | 1 | 4 | 4 | 94 | 38 | 56 | 60% | 6-2 | 3.22 | 1.14 |
| 2009-06-10 | John Danks | L | 24 | W 1-2 | vs DET | 12 | 71 | L | 7.1 | 5 | 2 | 2 | 1 | 2 | 7 | 98 | 34 | 64 | 65% | 4-5 | 4.84 | 1.42 |
| 2009-06-11 | Gavin Floyd | R | 26 | L 4-3 | vs DET | 13 | 75 | - | 8.0 | 5 | 1 | 1 | 1 | 0 | 5 | 111 | 34 | 77 | 69% | 4-5 | 4.94 | 1.39 |
| 2009-06-12 | Clayton Richard | L | 26 | L 2-7 | @ MIL | 7 | 15 | - | 5.0 | 4 | 1 | 0 | 0 | 3 | 3 | 102 | 41 | 61 | 60% | 2-1 | 3.76 | 1.53 |
| 2009-06-13 | Jose Contreras | R | 38 | W 7-1 | @ MIL | 8 | 160 | W | 8.0 | 2 | 0 | 0 | 0 | 2 | 8 | 106 | 40 | 66 | 62% | 2-5 | 5.28 | 1.35 |
| 2009-06-14 | Mark Buehrle | L | 30 | W 5-4 | @ MIL | 13 | 281 | - | 6.0 | 7 | 4 | 4 | 3 | 1 | 5 | 114 | 41 | 73 | 64% | 6-2 | 3.41 | 1.15 |
| 2009-06-17 | John Danks | L | 24 | W 4-1 | @ CHN | 13 | 72 | W | 7.0 | 5 | 1 | 1 | 0 | 0 | 9 | 96 | 28 | 68 | 71% | 5-5 | 4.50 | 1.35 |
| 2009-06-18 | Gavin Floyd | R | 26 | L 5-6 | @ CHN | 14 | 76 | - | 7.0 | 4 | 1 | 1 | 0 | 3 | 2 | 91 | 32 | 59 | 65% | 4-5 | 4.65 | 1.36 |
| 2009-06-19 | Jose Contreras | R | 38 | L 3-4 | @ CIN | 9 | 161 | L | 6.0 | 9 | 3 | 3 | 1 | 0 | 2 | 100 | 37 | 63 | 63% | 2-6 | 5.19 | 1.37 |
| 2009-06-20 | Clayton Richard | L | 26 | W 10-8 | @ CIN | 8 | 16 | - | 3.0 | 6 | 5 | 3 | 1 | 1 | 4 | 74 | 23 | 51 | 69% | 2-1 | 4.03 | 1.57 |
| 2009-06-21 | Mark Buehrle | L | 30 | W 4-1 | @ CIN | 14 | 282 | W | 7.0 | 5 | 0 | 0 | 0 | 1 | 3 | 103 | 36 | 67 | 65% | 7-2 | 3.16 | 1.13 |
| 2009-06-23 | John Danks | L | 24 | W 2-5 | vs LAN | 14 | 73 | L | 7.0 | 3 | 3 | 3 | 1 | 2 | 5 | 103 | 39 | 64 | 62% | 5-6 | 4.44 | 1.30 |
| 2009-06-24 | Gavin Floyd | R | 26 | L 10-7 | vs LAN | 15 | 77 | W | 6.0 | 6 | 3 | 1 | 0 | 2 | 3 | 108 | 33 | 75 | 69% | 5-5 | 4.45 | 1.36 |
| 2009-06-25 | Clayton Richard | L | 26 | L 6-5 | vs LAN | 9 | 17 | - | 4.1 | 6 | 4 | 4 | 0 | 1 | 1 | 85 | 36 | 49 | 58% | 2-1 | 4.35 | 1.58 |
| 2009-06-26 | Jose Contreras | R | 38 | W 4-5 | vs CHN | 10 | 162 | L | 7.1 | 7 | 5 | 4 | 2 | 1 | 8 | 102 | 38 | 64 | 63% | 2-7 | 5.19 | 1.34 |
| 2009-06-27 | Mark Buehrle | L | 30 | L 8-7 | vs CHN | 15 | 283 | - | 5.2 | 6 | 5 | 3 | 0 | 3 | 3 | 107 | 43 | 64 | 60% | 7-2 | 3.27 | 1.16 |
| 2009-06-28 | John Danks | L | 24 | L 6-0 | vs CHN | 15 | 74 | W | 7.0 | 4 | 0 | 0 | 0 | 4 | 5 | 109 | 48 | 61 | 56% | 6-6 | 4.09 | 1.28 |
| 2009-06-29 | Gavin Floyd | R | 26 | W 6-3 | @ CLE | 16 | 78 | W | 7.2 | 5 | 0 | 0 | 0 | 2 | 5 | 94 | 36 | 58 | 62% | 6-5 | 4.11 | 1.32 |
| 2009-06-30 | Clayton Richard | L | 26 | W 11-4 | @ CLE | 10 | 18 | W | 6.0 | 4 | 4 | 4 | 1 | 1 | 6 | 79 | 23 | 56 | 71% | 3-1 | 4.50 | 1.51 |
| 2009-07-01 | Jose Contreras | R | 38 | W 6-2 | @ CLE | 11 | 163 | W | 8.0 | 5 | 2 | 2 | 0 | 1 | 8 | 109 | 36 | 73 | 67% | 3-7 | 4.84 | 1.27 |
| 2009-07-02 | Mark Buehrle | L | 30 | W 4-1 | @ KCA | 16 | 284 | W | 8.1 | 6 | 1 | 1 | 0 | 0 | 1 | 100 | 32 | 68 | 68% | 8-2 | 3.08 | 1.12 |
| 2009-07-03 | John Danks | L | 24 | W 5-0 | @ KCA | 16 | 75 | W | 7.1 | 5 | 0 | 0 | 0 | 0 | 5 | 105 | 33 | 72 | 69% | 7-6 | 3.75 | 1.23 |
| 2009-07-04 | Gavin Floyd | R | 26 | L 4-6 | @ KCA | 17 | 79 | L | 5.1 | 4 | 5 | 5 | 0 | 3 | 4 | 106 | 48 | 58 | 55% | 6-6 | 4.33 | 1.32 |
| 2009-07-05 | Clayton Richard | L | 26 | L 3-6 | @ KCA | 11 | 19 | L | 3.2 | 8 | 4 | 4 | 0 | 0 | 3 | 84 | 32 | 52 | 62% | 3-2 | 4.75 | 1.54 |
| 2009-07-07 | Mark Buehrle | L | 30 | L 10-6 | vs CLE | 17 | 285 | W | 7.0 | 7 | 3 | 3 | 2 | 1 | 3 | 107 | 35 | 72 | 67% | 9-2 | 3.13 | 1.12 |
| 2009-07-08 | Jose Contreras | R | 38 | L 5-1 | vs CLE | 12 | 164 | W | 6.1 | 6 | 1 | 1 | 1 | 1 | 9 | 104 | 46 | 58 | 56% | 4-7 | 4.56 | 1.26 |
| 2009-07-09 | Clayton Richard | L | 26 | W 8-10 | vs CLE | 12 | 20 | L | 1.0 | 4 | 6 | 6 | 1 | 3 | 1 | 44 | 20 | 24 | 55% | 3-3 | 5.42 | 1.62 |
| 2009-07-10 | John Danks | L | 24 | L 4-6 | @ MIN | 17 | 76 | - | 5.2 | 4 | 4 | 4 | 0 | 5 | 4 | 118 | 45 | 73 | 62% | 7-6 | 3.92 | 1.26 |
| 2009-07-11 | Gavin Floyd | R | 26 | W 8-7 | @ MIN | 18 | 80 | W | 7.2 | 8 | 5 | 5 | 2 | 0 | 7 | 100 | 31 | 69 | 69% | 7-6 | 4.42 | 1.30 |
| 2009-07-12 | Mark Buehrle | L | 30 | L 7-13 | @ MIN | 18 | 286 | L | 3.1 | 10 | 8 | 8 | 3 | 1 | 1 | 65 | 21 | 44 | 68% | 9-3 | 3.66 | 1.19 |
| 2009-07-17 | John Danks | L | 24 | L 12-8 | vs BAL | 18 | 77 | W | 5.0 | 7 | 3 | 3 | 1 | 3 | 3 | 96 | 35 | 61 | 64% | 8-6 | 3.99 | 1.29 |
| 2009-07-18 | Mark Buehrle | L | 30 | L 4-3 | vs BAL | 19 | 287 | W | 7.1 | 8 | 1 | 1 | 0 | 0 | 4 | 109 | 37 | 72 | 66% | 10-3 | 3.53 | 1.18 |
| 2009-07-19 | Jose Contreras | R | 38 | W 2-10 | vs BAL | 13 | 165 | L | 4.1 | 5 | 5 | 4 | 0 | 4 | 1 | 99 | 41 | 58 | 59% | 4-8 | 4.73 | 1.29 |
| 2009-07-20 | Gavin Floyd | R | 26 | L 4-3 | vs TBA | 19 | 81 | W | 7.0 | 3 | 3 | 3 | 3 | 2 | 7 | 98 | 40 | 58 | 59% | 8-6 | 4.39 | 1.27 |
| 2009-07-21 | Clayton Richard | L | 26 | W 2-3 | vs TBA | 13 | 21 | - | 8.0 | 4 | 1 | 1 | 0 | 2 | 7 | 113 | 45 | 68 | 60% | 3-3 | 5.00 | 1.53 |
| 2009-07-22 | Carlos Torres | R | 27 | L 4-3 | vs TBA | 1 | 1 | - | 6.0 | 6 | 3 | 3 | 2 | 3 | 3 | 95 | 42 | 53 | 56% | 0-0 | 4.50 | 1.50 |
| 2009-07-23 | Mark Buehrle | L | 30 | L 5-0 | vs TBA | 20 | 288 | W | 9.0 | 0 | 0 | 0 | 0 | 0 | 6 | 114 | 40 | 74 | 65% | 11-3 | 3.29 | 1.10 |
| 2009-07-24 | Jose Contreras | R | 38 | L 1-5 | @ DET | 14 | 166 | L | 6.2 | 9 | 4 | 4 | 0 | 1 | 8 | 125 | 49 | 76 | 61% | 4-9 | 4.82 | 1.32 |
| 2009-07-24 | Bartolo Colon | R | 34 | L 3-4 | @ DET | 12 | 325 | - | 7.0 | 6 | 3 | 3 | 1 | 1 | 2 | 86 | 28 | 58 | 67% | 3-6 | 4.21 | 1.45 |
| 2009-07-25 | Gavin Floyd | R | 26 | L 3-4 | @ DET | 20 | 82 | - | 6.2 | 6 | 2 | 1 | 0 | 3 | 7 | 115 | 44 | 71 | 62% | 8-6 | 4.26 | 1.28 |
| 2009-07-26 | Clayton Richard | L | 26 | W 5-1 | @ DET | 14 | 22 | W | 8.0 | 5 | 1 | 1 | 0 | 2 | 3 | 114 | 42 | 72 | 63% | 4-3 | 4.65 | 1.47 |
| 2009-07-27 | John Danks | L | 24 | L 3-4 | @ MIN | 19 | 78 | L | 7.0 | 6 | 4 | 2 | 1 | 2 | 3 | 112 | 43 | 69 | 62% | 8-7 | 3.90 | 1.28 |
| 2009-07-28 | Mark Buehrle | L | 30 | L 3-5 | @ MIN | 21 | 289 | L | 6.1 | 5 | 5 | 5 | 0 | 1 | 3 | 97 | 32 | 65 | 67% | 11-4 | 3.45 | 1.09 |
| 2009-07-29 | Jose Contreras | R | 38 | L 2-3 | @ MIN | 15 | 167 | L | 5.2 | 6 | 3 | 3 | 0 | 5 | 4 | 118 | 57 | 61 | 52% | 4-10 | 4.80 | 1.36 |
| 2009-07-30 | Gavin Floyd | R | 27 | L 3-2 | vs NYA | 21 | 83 | - | 7.2 | 4 | 1 | 1 | 0 | 1 | 10 | 103 | 40 | 63 | 61% | 8-6 | 4.07 | 1.24 |
| 2009-07-31 | D.J. Carrasco | R | 32 | L 10-5 | vs NYA | 1 | 23 | - | 4.0 | 9 | 5 | 5 | 1 | 1 | 2 | 67 | 25 | 42 | 63% | 3-1 | 4.08 | 1.50 |
| 2009-08-01 | John Danks | L | 24 | L 14-4 | vs NYA | 20 | 79 | W | 6.0 | 7 | 4 | 4 | 0 | 4 | 5 | 98 | 37 | 61 | 62% | 9-7 | 4.01 | 1.31 |
| 2009-08-02 | Mark Buehrle | L | 30 | W 5-8 | vs NYA | 22 | 290 | L | 4.1 | 12 | 7 | 7 | 1 | 1 | 0 | 75 | 20 | 55 | 73% | 11-5 | 3.79 | 1.15 |
| 2009-08-04 | Jose Contreras | R | 38 | L 5-4 | vs ANA | 16 | 168 | - | 2.2 | 1 | 3 | 3 | 0 | 5 | 3 | 66 | 30 | 36 | 55% | 4-10 | 4.94 | 1.38 |
| 2009-08-05 | Gavin Floyd | R | 27 | L 6-2 | vs ANA | 22 | 84 | W | 8.0 | 6 | 2 | 1 | 0 | 1 | 6 | 104 | 40 | 64 | 62% | 9-6 | 3.91 | 1.22 |
| 2009-08-06 | John Danks | L | 24 | W 5-9 | vs ANA | 21 | 80 | L | 6.1 | 9 | 7 | 6 | 3 | 3 | 5 | 106 | 44 | 62 | 58% | 9-8 | 4.21 | 1.33 |
| 2009-08-07 | Mark Buehrle | L | 30 | W 2-6 | vs CLE | 23 | 291 | L | 7.2 | 11 | 6 | 5 | 2 | 2 | 2 | 115 | 42 | 73 | 63% | 11-6 | 3.88 | 1.18 |
| 2009-08-08 | Carlos Torres | R | 27 | L 8-5 | vs CLE | 2 | 2 | - | 3.1 | 3 | 4 | 4 | 0 | 6 | 5 | 72 | 39 | 33 | 46% | 0-0 | 7.00 | 2.00 |
| 2009-08-09 | Jose Contreras | R | 38 | W 4-8 | vs CLE | 17 | 169 | L | 4.2 | 6 | 4 | 4 | 0 | 2 | 2 | 87 | 33 | 54 | 62% | 4-11 | 5.10 | 1.40 |
| 2009-08-10 | Gavin Floyd | R | 27 | L 4-6 | @ SEA | 23 | 85 | L | 5.2 | 7 | 5 | 5 | 1 | 3 | 4 | 118 | 48 | 70 | 59% | 9-7 | 4.05 | 1.24 |
| 2009-08-11 | John Danks | L | 24 | W 3-1 | @ SEA | 22 | 81 | W | 8.0 | 7 | 1 | 1 | 0 | 1 | 8 | 98 | 30 | 68 | 69% | 10-8 | 4.03 | 1.31 |
| 2009-08-12 | Mark Buehrle | L | 30 | L 0-1 | @ SEA | 24 | 292 | - | 8.0 | 6 | 0 | 0 | 0 | 1 | 3 | 108 | 41 | 67 | 62% | 11-6 | 3.69 | 1.16 |
| 2009-08-14 | Jose Contreras | R | 38 | W 8-7 | @ OAK | 18 | 170 | - | 4.1 | 8 | 7 | 6 | 1 | 0 | 4 | 84 | 28 | 56 | 67% | 4-11 | 5.38 | 1.41 |
| 2009-08-15 | Gavin Floyd | R | 27 | W 8-1 | @ OAK | 24 | 86 | W | 7.0 | 8 | 1 | 1 | 0 | 2 | 8 | 99 | 31 | 68 | 69% | 10-7 | 3.93 | 1.25 |
| 2009-08-16 | John Danks | L | 24 | L 2-3 | @ OAK | 23 | 82 | - | 7.1 | 8 | 2 | 2 | 0 | 1 | 3 | 94 | 32 | 62 | 66% | 10-8 | 3.96 | 1.31 |
| 2009-08-17 | Mark Buehrle | L | 30 | L 8-7 | vs KCA | 25 | 293 | - | 6.0 | 9 | 4 | 4 | 1 | 2 | 0 | 96 | 34 | 62 | 65% | 11-6 | 3.77 | 1.19 |
| 2009-08-18 | Freddy Garcia | R | 33 | W 4-5 | vs KCA | 1 | 266 | L | 4.1 | 7 | 5 | 5 | 1 | 1 | 3 | 91 | 38 | 53 | 58% | 0-1 | 11.25 | 2.00 |
| 2009-08-19 | Jose Contreras | R | 38 | L 4-2 | vs KCA | 19 | 171 | W | 7.0 | 3 | 1 | 1 | 1 | 1 | 8 | 97 | 33 | 64 | 66% | 5-11 | 5.12 | 1.36 |
| 2009-08-21 | Gavin Floyd | R | 27 | W 1-5 | vs BAL | 25 | 87 | L | 7.1 | 7 | 4 | 4 | 2 | 2 | 7 | 113 | 45 | 68 | 60% | 10-8 | 3.98 | 1.25 |
| 2009-08-22 | John Danks | L | 24 | L 4-1 | vs BAL | 24 | 83 | W | 6.1 | 3 | 1 | 1 | 0 | 6 | 3 | 99 | 43 | 56 | 57% | 11-8 | 3.86 | 1.32 |
| 2009-08-23 | Mark Buehrle | L | 30 | W 4-5 | vs BAL | 26 | 294 | L | 5.1 | 11 | 5 | 5 | 2 | 0 | 4 | 102 | 31 | 71 | 70% | 11-7 | 3.92 | 1.22 |
| 2009-08-24 | Jose Contreras | R | 38 | L 8-12 | @ BOS | 20 | 172 | L | 2.2 | 4 | 7 | 1 | 1 | 3 | 1 | 93 | 43 | 50 | 54% | 5-12 | 5.11 | 1.40 |
| 2009-08-25 | Freddy Garcia | R | 33 | L 3-6 | @ BOS | 2 | 267 | - | 6.1 | 5 | 3 | 3 | 0 | 1 | 5 | 94 | 37 | 57 | 61% | 0-1 | 6.55 | 1.27 |
| 2009-08-26 | Gavin Floyd | R | 27 | L 2-3 | @ BOS | 26 | 88 | - | 6.0 | 5 | 2 | 2 | 2 | 1 | 4 | 107 | 39 | 68 | 64% | 10-8 | 3.95 | 1.24 |
| 2009-08-27 | John Danks | L | 24 | W 9-5 | @ BOS | 25 | 84 | W | 6.0 | 6 | 2 | 2 | 2 | 1 | 6 | 108 | 38 | 70 | 65% | 12-8 | 3.82 | 1.31 |
| 2009-08-28 | Mark Buehrle | L | 30 | L 2-5 | @ NYA | 27 | 295 | - | 6.0 | 8 | 2 | 2 | 2 | 2 | 1 | 99 | 41 | 58 | 59% | 11-7 | 3.89 | 1.23 |
| 2009-08-29 | Jose Contreras | R | 38 | L 0-10 | @ NYA | 21 | 173 | L | 3.1 | 9 | 8 | 6 | 0 | 2 | 3 | 78 | 29 | 49 | 63% | 5-13 | 5.40 | 1.44 |
| 2009-08-30 | Freddy Garcia | R | 33 | L 3-8 | @ NYA | 3 | 268 | L | 6.0 | 4 | 3 | 3 | 1 | 3 | 5 | 96 | 39 | 57 | 59% | 0-2 | 5.82 | 1.24 |
| 2009-08-31 | Gavin Floyd | R | 27 | L 1-4 | @ MIN | 27 | 89 | L | 6.0 | 9 | 3 | 3 | 2 | 0 | 4 | 109 | 39 | 70 | 64% | 10-9 | 3.97 | 1.25 |
| 2009-09-01 | John Danks | L | 24 | L 3-4 | @ MIN | 26 | 85 | - | 7.0 | 6 | 3 | 3 | 2 | 2 | 2 | 95 | 33 | 62 | 65% | 12-8 | 3.83 | 1.31 |
| 2009-09-02 | Mark Buehrle | L | 30 | W 4-2 | @ MIN | 28 | 296 | - | 6.0 | 7 | 2 | 2 | 0 | 1 | 2 | 81 | 27 | 54 | 67% | 11-7 | 3.86 | 1.23 |
| 2009-09-03 | Carlos Torres | R | 27 | W 5-0 | @ CHN | 3 | 3 | W | 7.0 | 5 | 0 | 0 | 0 | 0 | 6 | 98 | 33 | 65 | 66% | 1-0 | 3.94 | 1.44 |
| 2009-09-04 | Freddy Garcia | R | 33 | L 12-2 | vs BOS | 4 | 269 | W | 6.0 | 7 | 1 | 1 | 0 | 1 | 5 | 82 | 30 | 52 | 63% | 1-2 | 4.70 | 1.26 |
| 2009-09-05 | Gavin Floyd | R | 27 | L 5-1 | vs BOS | 28 | 90 | W | 8.0 | 3 | 1 | 1 | 1 | 0 | 11 | 106 | 39 | 67 | 63% | 11-9 | 3.84 | 1.21 |
| 2009-09-06 | John Danks | L | 24 | W 1-6 | vs BOS | 27 | 86 | L | 6.0 | 7 | 3 | 3 | 1 | 1 | 4 | 105 | 36 | 69 | 66% | 12-9 | 3.85 | 1.31 |
| 2009-09-07 | Mark Buehrle | L | 30 | L 5-1 | vs BOS | 29 | 297 | W | 7.0 | 8 | 1 | 1 | 0 | 2 | 4 | 104 | 34 | 70 | 67% | 12-7 | 3.77 | 1.24 |
| 2009-09-08 | Carlos Torres | R | 27 | W 3-11 | vs OAK | 4 | 4 | L | 0.2 | 4 | 5 | 5 | 2 | 1 | 1 | 22 | 6 | 16 | 73% | 1-1 | 6.35 | 1.65 |
| 2009-09-09 | Freddy Garcia | R | 33 | L 4-3 | vs OAK | 5 | 270 | - | 6.0 | 5 | 2 | 2 | 0 | 3 | 5 | 87 | 34 | 53 | 61% | 1-2 | 4.34 | 1.28 |
| 2009-09-11 | Gavin Floyd | R | 27 | L 1-7 | @ ANA | 29 | 91 | L | 5.0 | 6 | 5 | 5 | 0 | 2 | 2 | 98 | 36 | 62 | 63% | 11-10 | 3.98 | 1.22 |
| 2009-09-12 | John Danks | L | 24 | W 4-3 | @ ANA | 28 | 87 | - | 6.0 | 6 | 0 | 0 | 0 | 2 | 5 | 108 | 43 | 65 | 60% | 12-9 | 3.72 | 1.31 |
| 2009-09-13 | Mark Buehrle | L | 30 | L 2-3 | @ ANA | 30 | 298 | L | 7.0 | 5 | 3 | 2 | 1 | 2 | 3 | 99 | 35 | 64 | 65% | 12-8 | 3.73 | 1.23 |
| 2009-09-15 | Freddy Garcia | R | 33 | W 6-3 | @ SEA | 6 | 271 | W | 6.0 | 7 | 3 | 3 | 1 | 1 | 1 | 100 | 39 | 61 | 61% | 2-2 | 4.37 | 1.29 |
| 2009-09-16 | Gavin Floyd | R | 27 | L 1-4 | @ SEA | 30 | 92 | L | 3.0 | 4 | 3 | 3 | 0 | 1 | 1 | 42 | 14 | 28 | 67% | 11-11 | 4.06 | 1.23 |
| 2009-09-17 | John Danks | L | 24 | L 3-4 | @ SEA | 29 | 88 | - | 8.0 | 4 | 1 | 1 | 1 | 2 | 3 | 98 | 34 | 64 | 65% | 12-9 | 3.60 | 1.28 |
| 2009-09-18 | Mark Buehrle | L | 30 | W 0-11 | vs KCA | 31 | 299 | L | 6.0 | 7 | 5 | 5 | 1 | 4 | 4 | 99 | 43 | 56 | 57% | 12-9 | 3.84 | 1.25 |
| 2009-09-19 | Jake Peavy | R | 28 | L 13-3 | vs KCA | 14 | 213 | W | 5.0 | 3 | 3 | 3 | 1 | 2 | 5 | 72 | 26 | 46 | 64% | 7-6 | 4.03 | 1.17 |
| 2009-09-20 | Freddy Garcia | R | 33 | W 1-2 | vs KCA | 7 | 272 | L | 8.0 | 5 | 2 | 2 | 0 | 1 | 3 | 90 | 24 | 66 | 73% | 2-3 | 3.98 | 1.19 |
| 2009-09-21 | Daniel Hudson | R | 23 | W 0-7 | vs MIN | 1 | 1 | L | 5.0 | 4 | 3 | 1 | 0 | 4 | 4 | 98 | 34 | 64 | 65% | 0-1 | 3.27 | 1.27 |
| 2009-09-22 | John Danks | L | 24 | W 6-8 | vs MIN | 30 | 89 | L | 6.0 | 8 | 7 | 7 | 3 | 3 | 2 | 98 | 40 | 58 | 59% | 12-10 | 3.82 | 1.30 |
| 2009-09-23 | Mark Buehrle | L | 31 | W 6-8 | vs MIN | 32 | 300 | L | 3.1 | 8 | 5 | 4 | 0 | 1 | 0 | 57 | 19 | 38 | 67% | 12-10 | 3.96 | 1.28 |
| 2009-09-25 | Jake Peavy | R | 28 | L 2-0 | vs DET | 15 | 214 | W | 7.0 | 6 | 0 | 0 | 0 | 2 | 8 | 93 | 27 | 66 | 71% | 8-6 | 3.73 | 1.17 |
| 2009-09-26 | Freddy Garcia | R | 33 | W 5-12 | vs DET | 8 | 273 | L | 6.1 | 10 | 7 | 7 | 1 | 0 | 3 | 87 | 25 | 62 | 71% | 2-4 | 4.78 | 1.24 |
| 2009-09-27 | Daniel Hudson | R | 23 | L 8-4 | vs DET | 2 | 2 | W | 6.0 | 3 | 2 | 2 | 1 | 5 | 4 | 95 | 43 | 52 | 55% | 1-1 | 3.18 | 1.29 |
| 2009-09-28 | John Danks | L | 24 | W 6-1 | @ CLE | 31 | 90 | W | 9.0 | 3 | 1 | 1 | 1 | 1 | 7 | 114 | 43 | 71 | 62% | 13-10 | 3.69 | 1.26 |
| 2009-09-30 | Carlos Torres | R | 27 | L 1-5 | @ CLE | 5 | 5 | L | 6.0 | 6 | 5 | 5 | 1 | 4 | 4 | 113 | 49 | 64 | 57% | 1-2 | 6.33 | 1.67 |
| 2009-09-30 | Mark Buehrle | L | 31 | W 1-0 | @ CLE | 33 | 301 | W | 6.0 | 3 | 0 | 0 | 0 | 0 | 3 | 81 | 27 | 54 | 67% | 13-10 | 3.85 | 1.25 |
| 2009-10-02 | Jake Peavy | R | 28 | W 8-0 | @ DET | 16 | 215 | W | 8.0 | 2 | 0 | 0 | 0 | 2 | 5 | 106 | 37 | 69 | 65% | 9-6 | 3.44 | 1.12 |
| 2009-10-03 | Freddy Garcia | R | 33 | W 5-1 | @ DET | 9 | 274 | W | 7.0 | 6 | 1 | 1 | 0 | 1 | 7 | 98 | 33 | 65 | 66% | 3-4 | 4.34 | 1.21 |
| 2009-10-04 | John Danks | L | 24 | L 3-5 | @ DET | 32 | 91 | L | 5.0 | 7 | 4 | 4 | 2 | 4 | 1 | 89 | 36 | 53 | 60% | 13-11 | 3.78 | 1.29 |