| East | W | L | Pct | GB |
| NY Yankees | 103 | 59 | .636 | -- |
| Boston | 95 | 67 | .586 | 8.0 |
| Tampa Bay | 84 | 78 | .519 | 19.0 |
| Toronto | 75 | 87 | .463 | 28.0 |
| Baltimore | 64 | 98 | .395 | 39.0 |
| # | Player | Pos | Rk | Age | Drafted | HiLvl | G | AB | R | H | 2B | 3B | HR | RBI | SB | CS | BB | SO | HBP | IBB | SH | SF | DP | AVG | OBP | SLG | OPS | TB | PA | OUT | RC | RC/G | babip |
| 15 | Dustin Pedroia | 2b | 22 | 25 | 2004-2-65 | MLB | 154 | 626 | 115 | 185 | 48 | 1 | 15 | 72 | 20 | 8 | 74 | 45 | 5 | 3 | 3 | 6 | 19 | .296 | .371 | .447 | 819 | 280 | 714 | 477 | 119 | 6.7 | .297 |
| 46 | Jacoby Ellsbury | cf | 25 | 25 | 2005-1-23 | MLB | 153 | 624 | 94 | 188 | 27 | 10 | 8 | 60 | 70 | 12 | 49 | 74 | 6 | 3 | 6 | 6 | 13 | .301 | .355 | .415 | 770 | 259 | 691 | 473 | 107 | 6.1 | .328 |
| 34 | David Ortiz | dh | 53 | 33 | UDFA: 1992 | MLB | 150 | 541 | 77 | 129 | 35 | 1 | 28 | 99 | 0 | 2 | 74 | 134 | 5 | 5 | 0 | 7 | 9 | .238 | .332 | .462 | 794 | 250 | 627 | 430 | 88 | 5.5 | .262 |
| 44 | Jason Bay | lf | 5 | 30 | 2000-22-645 | MLB | 151 | 531 | 103 | 142 | 29 | 3 | 36 | 119 | 13 | 3 | 94 | 162 | 9 | 4 | 0 | 4 | 9 | .267 | .384 | .537 | 921 | 285 | 638 | 405 | 114 | 7.6 | .315 |
| 20 | Kevin Youkilis | 3b | 15 | 30 | 2001-8-243 | MLB | 136 | 491 | 99 | 150 | 36 | 1 | 27 | 94 | 7 | 2 | 77 | 125 | 16 | 6 | 0 | 4 | 9 | .305 | .413 | .548 | 961 | 269 | 588 | 356 | 116 | 8.8 | .359 |
| 7 | J.D. Drew | rf | 34 | 33 | 1998-1-5 | MLB | 137 | 452 | 84 | 126 | 30 | 4 | 24 | 68 | 2 | 6 | 82 | 109 | 3 | 5 | 1 | 1 | 6 | .279 | .392 | .522 | 914 | 236 | 539 | 340 | 97 | 7.7 | .319 |
| 25 | Mike Lowell | 3b | - | 35 | 1995-20-562 | MLB | 119 | 445 | 54 | 129 | 29 | 1 | 17 | 75 | 2 | 1 | 33 | 61 | 1 | 5 | 0 | 5 | 24 | .290 | .337 | .474 | 811 | 211 | 484 | 346 | 72 | 5.6 | .301 |
| 33 | Jason Varitek | c | 100 | 37 | 1994-1-14 | MLB | 109 | 364 | 41 | 76 | 24 | 0 | 14 | 51 | 0 | 0 | 54 | 90 | 3 | 6 | 0 | 4 | 6 | .209 | .313 | .390 | 703 | 142 | 425 | 298 | 48 | 4.3 | .235 |
| 22 | Nick Green | 2b-ss | 93 | 30 | 1999-32-971 | MLB | 103 | 276 | 35 | 65 | 18 | 0 | 6 | 35 | 1 | 4 | 20 | 69 | 8 | 1 | 2 | 3 | 10 | .236 | .303 | .366 | 669 | 101 | 309 | 230 | 28 | 3.2 | .289 |
| 41 | Victor Martinez | dh | 31 | 30 | UDFA: 1996 | MLB | 56 | 211 | 32 | 71 | 12 | 0 | 8 | 41 | 1 | 0 | 24 | 23 | 1 | 0 | 0 | 1 | 6 | .336 | .405 | .507 | 912 | 107 | 237 | 147 | 46 | 8.5 | .348 |
| 5 | Rocco Baldelli | cf | - | 27 | 2000-1-6 | MLB | 62 | 150 | 23 | 38 | 4 | 1 | 7 | 23 | 1 | 0 | 11 | 37 | 2 | 0 | 0 | 1 | 6 | .253 | .311 | .433 | 744 | 65 | 164 | 119 | 19 | 4.3 | .290 |
| 3 | Alex Gonzalez | ss | - | 32 | UDFA: 1994 | MLB | 44 | 148 | 26 | 42 | 10 | 0 | 5 | 15 | 2 | 0 | 5 | 29 | 2 | 0 | 4 | 0 | 4 | .284 | .316 | .453 | 769 | 67 | 159 | 114 | 22 | 5.2 | .325 |
| 23 | Julio Lugo | ss-3b | - | 33 | 1994-43-1193 | MLB | 37 | 109 | 16 | 31 | 4 | 1 | 1 | 8 | 3 | 0 | 12 | 18 | 0 | 0 | 1 | 1 | 0 | .284 | .352 | .367 | 719 | 40 | 123 | 80 | 16 | 5.5 | .330 |
| 16 | George Kottaras | c | - | 26 | 2002-20-595 | MLB | 45 | 93 | 15 | 22 | 11 | 0 | 1 | 10 | 0 | 0 | 11 | 25 | 0 | 0 | 0 | 3 | 1 | .237 | .308 | .387 | 696 | 36 | 107 | 75 | 12 | 4.5 | .300 |
| 11 | Casey Kotchman | 1b | - | 26 | 2001-1-13 | MLB | 39 | 87 | 9 | 19 | 3 | 0 | 1 | 7 | 1 | 0 | 7 | 14 | 1 | 0 | 0 | 0 | 4 | .218 | .284 | .287 | 572 | 25 | 95 | 72 | 6 | 2.3 | .250 |
| 55 | Jeff Bailey | 1b | - | 30 | 1997-2-64 | MLB | 26 | 77 | 14 | 16 | 3 | 2 | 3 | 9 | 0 | 0 | 10 | 21 | 4 | 0 | 0 | 0 | 5 | .208 | .330 | .416 | 745 | 32 | 91 | 66 | 10 | 4.1 | .245 |
| 11 | Mark Kotsay | lf | - | 33 | 1996-1-9 | MLB | 27 | 74 | 4 | 19 | 2 | 0 | 1 | 5 | 2 | 1 | 4 | 12 | 0 | 1 | 0 | 1 | 1 | .257 | .291 | .324 | 615 | 24 | 79 | 58 | 7 | 3.2 | .290 |
| 12 | Jed Lowrie | ss | - | 25 | 2005-1-45 | MLB | 32 | 68 | 5 | 10 | 2 | 0 | 2 | 11 | 0 | 0 | 6 | 20 | 0 | 0 | 0 | 2 | 0 | .147 | .211 | .265 | 475 | 18 | 76 | 60 | 3 | 1.2 | .167 |
| 68 | Josh Reddick | rf | - | 22 | 2006-17-523 | MLB | 27 | 59 | 5 | 10 | 4 | 0 | 2 | 4 | 0 | 0 | 2 | 17 | 1 | 0 | 0 | 0 | 0 | .169 | .210 | .339 | 549 | 20 | 62 | 49 | 4 | 2.1 | .200 |
| 23 | Adam LaRoche | 1b | - | 29 | 2000-29-880 | MLB | 6 | 19 | 2 | 5 | 2 | 0 | 1 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | .263 | .263 | .526 | 789 | 10 | 19 | 15 | 3 | 5.2 | .250 |
| 32 | Brian Anderson | p | - | 27 | 2003-1-15 | MLB | 21 | 17 | 7 | 5 | 0 | 0 | 2 | 5 | 0 | 0 | 3 | 5 | 0 | 0 | 0 | 1 | 2 | .294 | .381 | .647 | 1028 | 11 | 21 | 15 | 4 | 6.5 | .273 |
| 23 | Joey Gathright | cf | - | 27 | 2001-32-949 | MLB | 17 | 16 | 7 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 2 | .312 | .353 | .312 | 665 | 5 | 17 | 13 | 1 | 2.6 | .357 |
| 30 | Chris Woodward | 3b | - | 33 | 1994-54-1437 | MLB | 13 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 2 | 0 | 0 | 0 | 0 | .083 | .312 | .083 | 396 | 1 | 16 | 11 | 0 | 0.7 | .125 |
| 50 | Aaron Bates | 1b | - | 25 | 2006-3-83 | MLB | 5 | 11 | 2 | 4 | 2 | 0 | 0 | 2 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | .364 | .417 | .545 | 962 | 6 | 12 | 7 | 3 | 9.7 | .571 |
| 30 | Jon Van Every | of | - | 29 | 2000-29-876 | MLB | 7 | 11 | 1 | 4 | 0 | 0 | 1 | 3 | 0 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | .364 | .462 | .636 | 1098 | 7 | 13 | 7 | 3 | 11.1 | .600 |
| 19 | Josh Beckett | p | - | 29 | 1999-1-2 | MLB | 2 | 5 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | .200 | .200 | .800 | 1000 | 4 | 5 | 4 | 1 | 6.0 | .000 |
| 54 | Chris Carter | lf-rf | - | 26 | 2004-17-506 | MLB | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | .000 | .000 | .000 | 0 | 0 | 6 | 6 | - | - | .000 |
| 36 | Brad Penny | p | - | 31 | 1996-5-155 | MLB | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 5 | 5 | - | - | .000 |
| 31 | Jon Lester | p | - | 25 | 2002-2-57 | MLB | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 5 | 5 | - | - | .000 |
| 50 | Dusty Brown | c | - | 27 | 2000-35-1052 | MLB | 6 | 3 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .333 | .500 | 1.333 | 1833 | 4 | 4 | 2 | 2 | 26.0 | .000 |
| 29 | John Smoltz | p | - | 42 | 1985-22-574 | MLB | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 2 | 2 | - | - | .000 |
| 18 | Daisuke Matsuzaka | p | - | 28 | UDFA: 2008 | MLB | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 2 | 2 | - | - | .000 |
| 51 | Gil Velazquez | ss | - | 29 | 1998-14-424 | MLB | 6 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | .000 | .333 | .000 | 333 | 0 | 3 | 2 | 0 | 1.6 | .000 |
| 49 | Tim Wakefield | p | - | 42 | 1988-8-200 | MLB | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | .500 | .500 | .500 | 1000 | 1 | 2 | 1 | 0 | 9.9 | 1.000 |
| 56 | Ramon Ramirez | p | - | 27 | UDFA: 2003 | MLB | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 1 | 1 | - | - | .000 |
| 37 | Hideki Okajima | p | - | 33 | UDFA: 2010 | MLB | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 1 | 1 | - | - | .000 |
| Totals: (36 players) | 162 | 5543 | 872 | 1495 | 335 | 25 | 212 | 822 | 126 | 39 | 659 | 1120 | 70 | 39 | 19 | 51 | 137 | .270 | .352 | .454 | 806 | 2516 | 6342 | 4294 | 945 | 5.9 | .301 | ||||||
| # | Player | Rk | Age | Drafted | HiLvl | W | L | ERA | G | GS | CG | SH | GF | SV | IP | H | R | ER | HR | BB | SO | WP | Bk | WHIP | H9 | HR9 | BB9 | SO9 | BB/SO | BABIP | GB/FB |
| 19 | Josh Beckett | 6 | 29 | 1999-1-2 | MLB | 17 | 6 | 3.86 | 32 | 32 | 4 | 2 | 0 | 0 | 212.1 | 198 | 99 | 91 | 25 | 55 | 199 | 3 | 1 | 1.19 | 8.39 | 1.06 | 2.33 | 8.43 | 0.28 | .295 | 0.93 |
| 31 | Jon Lester | 8 | 25 | 2002-2-57 | MLB | 15 | 8 | 3.41 | 32 | 32 | 2 | 0 | 0 | 0 | 203.1 | 186 | 80 | 77 | 20 | 64 | 225 | 6 | 0 | 1.23 | 8.23 | 0.89 | 2.83 | 9.96 | 0.28 | .317 | 0.95 |
| 36 | Brad Penny | - | 31 | 1996-5-155 | MLB | 7 | 8 | 5.61 | 24 | 24 | 0 | 0 | 0 | 0 | 131.2 | 160 | 89 | 82 | 17 | 42 | 89 | 4 | 0 | 1.53 | 10.94 | 1.16 | 2.87 | 6.08 | 0.47 | .333 | 0.71 |
| 49 | Tim Wakefield | 62 | 42 | 1988-8-200 | MLB | 11 | 5 | 4.58 | 21 | 21 | 2 | 0 | 0 | 0 | 129.2 | 137 | 67 | 66 | 12 | 50 | 72 | 4 | 0 | 1.44 | 9.51 | 0.83 | 3.47 | 5.00 | 0.69 | .296 | 0.60 |
| 61 | Clay Buchholz | - | 24 | 2005-1-42 | MLB | 7 | 4 | 4.21 | 16 | 16 | 0 | 0 | 0 | 0 | 92.0 | 91 | 44 | 43 | 13 | 36 | 68 | 1 | 0 | 1.38 | 8.90 | 1.27 | 3.52 | 6.65 | 0.53 | .284 | 1.17 |
| 18 | Justin Masterson | - | 24 | 2006-2-71 | MLB | 3 | 3 | 4.50 | 31 | 6 | 0 | 0 | 4 | 0 | 72.0 | 72 | 38 | 36 | 7 | 25 | 67 | 3 | 0 | 1.35 | 9.00 | 0.88 | 3.13 | 8.38 | 0.37 | .339 | 1.14 |
| 56 | Ramon Ramirez | 73 | 27 | UDFA: 2003 | MLB | 7 | 4 | 2.84 | 70 | 0 | 0 | 0 | 16 | 0 | 69.2 | 61 | 26 | 22 | 7 | 32 | 52 | 2 | 2 | 1.33 | 7.88 | 0.90 | 4.13 | 6.72 | 0.62 | .266 | 0.58 |
| 58 | Jonathan Papelbon | 33 | 28 | 2003-4-114 | MLB | 1 | 1 | 1.85 | 66 | 0 | 0 | 0 | 59 | 38 | 68.0 | 54 | 15 | 14 | 5 | 24 | 76 | 0 | 0 | 1.15 | 7.15 | 0.66 | 3.18 | 10.06 | 0.32 | .283 | 0.39 |
| 37 | Hideki Okajima | 84 | 33 | UDFA: 2010 | MLB | 6 | 0 | 3.39 | 68 | 0 | 0 | 0 | 6 | 0 | 61.0 | 56 | 23 | 23 | 8 | 21 | 53 | 0 | 0 | 1.26 | 8.26 | 1.18 | 3.10 | 7.82 | 0.40 | .282 | 0.50 |
| 17 | Manny Delcarmen | - | 27 | 2000-2-62 | MLB | 5 | 2 | 4.53 | 64 | 0 | 0 | 0 | 6 | 0 | 59.2 | 64 | 34 | 30 | 5 | 34 | 44 | 1 | 0 | 1.64 | 9.65 | 0.75 | 5.13 | 6.64 | 0.77 | .314 | 0.77 |
| 18 | Daisuke Matsuzaka | - | 28 | UDFA: 2008 | MLB | 4 | 6 | 5.76 | 12 | 12 | 0 | 0 | 0 | 0 | 59.1 | 81 | 38 | 38 | 10 | 30 | 54 | 8 | 0 | 1.87 | 12.29 | 1.52 | 4.55 | 8.19 | 0.56 | .384 | 0.54 |
| 24 | Takashi Saito | 74 | 39 | UDFA: 2010 | MLB | 3 | 3 | 2.43 | 56 | 0 | 0 | 0 | 30 | 2 | 55.2 | 50 | 16 | 15 | 6 | 25 | 52 | 1 | 0 | 1.35 | 8.08 | 0.97 | 4.04 | 8.41 | 0.48 | .299 | 0.53 |
| 60 | Daniel Bard | - | 24 | 2006-1-28 | MLB | 2 | 2 | 3.65 | 49 | 0 | 0 | 0 | 12 | 1 | 49.1 | 41 | 24 | 20 | 5 | 22 | 63 | 1 | 1 | 1.28 | 7.48 | 0.91 | 4.01 | 11.49 | 0.35 | .321 | 0.91 |
| 29 | John Smoltz | - | 42 | 1985-22-574 | MLB | 2 | 5 | 8.32 | 8 | 8 | 0 | 0 | 0 | 0 | 40.0 | 59 | 37 | 37 | 8 | 9 | 33 | 0 | 0 | 1.70 | 13.27 | 1.80 | 2.02 | 7.43 | 0.27 | .389 | 0.74 |
| 36 | Paul Byrd | - | 38 | 1991-4-113 | MLB | 1 | 3 | 5.82 | 7 | 6 | 0 | 0 | 0 | 0 | 34.0 | 47 | 22 | 22 | 4 | 11 | 11 | 0 | 0 | 1.71 | 12.44 | 1.06 | 2.91 | 2.91 | 1.00 | .339 | 0.60 |
| 63 | Junichi Tazawa | - | 23 | UDFA: 2009 | MLB | 2 | 3 | 7.46 | 6 | 4 | 0 | 0 | 1 | 0 | 25.1 | 43 | 23 | 21 | 4 | 9 | 13 | 0 | 0 | 2.05 | 15.28 | 1.42 | 3.20 | 4.62 | 0.69 | .398 | 0.30 |
| 64 | Mike Bowden | - | 22 | 2005-1-47 | MLB | 1 | 1 | 9.56 | 8 | 1 | 0 | 0 | 3 | 0 | 16.0 | 23 | 17 | 17 | 3 | 6 | 12 | 3 | 0 | 1.81 | 12.94 | 1.69 | 3.38 | 6.75 | 0.50 | .370 | 0.73 |
| 13 | Billy Wagner | - | 37 | 1993-1-12 | MLB | 1 | 1 | 1.98 | 15 | 0 | 0 | 0 | 2 | 0 | 13.2 | 8 | 5 | 3 | 1 | 7 | 22 | 1 | 0 | 1.10 | 5.27 | 0.66 | 4.61 | 14.49 | 0.32 | .304 | 0.44 |
| 62 | Hunter Jones | - | 25 | UDFA: 2005 | MLB | 0 | 0 | 9.24 | 11 | 0 | 0 | 0 | 1 | 0 | 12.2 | 16 | 13 | 13 | 3 | 7 | 9 | 2 | 0 | 1.82 | 11.37 | 2.13 | 4.97 | 6.39 | 0.78 | .317 | 0.44 |
| 48 | Javier Lopez | - | 31 | 1998-4-133 | MLB | 0 | 2 | 9.26 | 14 | 0 | 0 | 0 | 5 | 0 | 11.2 | 20 | 13 | 12 | 1 | 9 | 5 | 1 | 0 | 2.49 | 15.43 | 0.77 | 6.94 | 3.86 | 1.80 | .422 | 1.00 |
| 53 | Fernando Cabrera | - | 27 | 1999-10-317 | MLB | 0 | 0 | 8.44 | 6 | 0 | 0 | 0 | 3 | 0 | 5.1 | 7 | 5 | 5 | 0 | 4 | 8 | 0 | 0 | 2.06 | 11.81 | 0.00 | 6.75 | 13.50 | 0.50 | .467 | 0.67 |
| 51 | Enrique Gonzalez | - | 26 | UDFA: 1998 | MLB | 0 | 0 | 4.91 | 2 | 0 | 0 | 0 | 2 | 0 | 3.2 | 5 | 2 | 2 | 1 | 2 | 1 | 0 | 0 | 1.91 | 12.27 | 2.45 | 4.91 | 2.45 | 2.00 | .286 | 0.50 |
| 40 | Billy Traber | - | 29 | 2000-1-16 | MLB | 0 | 0 | 12.27 | 1 | 0 | 0 | 0 | 0 | 0 | 3.2 | 9 | 5 | 5 | 2 | 1 | 1 | 0 | 0 | 2.73 | 22.09 | 4.91 | 2.45 | 2.45 | 1.00 | .437 | 0.64 |
| 54 | Dustin Richardson | - | 25 | 2006-5-163 | MLB | 0 | 0 | 0.00 | 3 | 0 | 0 | 0 | 1 | 0 | 3.1 | 3 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1.20 | 8.10 | 0.00 | 2.70 | 0.00 | -- | .250 | 0.63 |
| 22 | Nick Green | - | 30 | 1999-32-971 | MLB | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 2.0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 1.50 | 0.00 | 0.00 | 13.50 | 0.00 | -- | .000 | 1.00 |
| 50 | Dusty Brown | - | 27 | 2000-35-1052 | MLB | 0 | 0 | 9.00 | 1 | 0 | 0 | 0 | 1 | 0 | 1.0 | 2 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 2.00 | 18.00 | 0.00 | 0.00 | 9.00 | 0.00 | .500 | 0.33 |
| 30 | Jon Van Every | - | 29 | 2000-29-876 | MLB | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 0 | 0 | 0.2 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 3.00 | 13.50 | 0.00 | 13.50 | 0.00 | -- | .333 | 0.00 |
| Totals: (36 players) | 95 | 67 | 4.35 | 162 | 162 | 8 | 2 | 154 | 41 | 1,437 | 1494 | 736 | 695 | 212 | 530 | 1230 | 42 | 5 | 1.50 | 9.36 | 1.05 | 3.32 | 7.71 | 0.43 | .309 | ||||||
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Jason Varitek | C | 108 | 924 | 856 | 37 | 3 | 4 | .997 | 8.70 | |
| George Kottaras | C | 39 | 243 | 196 | 8 | 1 | 1 | .995 | 7.55 | |
| Victor Martinez | C | 33 | 257 | 215 | 8 | 4 | 1 | .982 | 7.81 | |
| Dusty Brown | C | 6 | 12 | 6 | 2 | 0 | 0 | 1.000 | 6.00 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Kevin Youkilis | 1B | 78 | 647 | 565 | 52 | 1 | 56 | .998 | 8.58 | |
| Casey Kotchman | 1B | 29 | 190 | 185 | 19 | 0 | 12 | 1.000 | 9.66 | |
| Jeff Bailey | 1B | 23 | 180 | 158 | 11 | 2 | 13 | .988 | 8.45 | |
| Victor Martinez | 1B | 23 | 189 | 160 | 3 | 0 | 14 | 1.000 | 7.76 | |
| Mark Kotsay | 1B | 19 | 125 | 103 | 11 | 0 | 9 | 1.000 | 8.20 | |
| David Ortiz | 1B | 6 | 39 | 42 | 6 | 1 | 2 | .980 | 11.08 | |
| Aaron Bates | 1B | 5 | 30 | 35 | 0 | 1 | 3 | .972 | 10.50 | |
| Adam LaRoche | 1B | 4 | 36 | 29 | 6 | 0 | 1 | 1.000 | 8.75 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Dustin Pedroia | 2B | 154 | 1346 | 253 | 404 | 6 | 93 | .991 | 4.39 | |
| Nick Green | 2B | 7 | 58 | 12 | 17 | 0 | 2 | 1.000 | 4.50 | |
| Chris Woodward | 2B | 6 | 27 | 5 | 6 | 0 | 0 | 1.000 | 3.67 | |
| Jed Lowrie | 2B | 2 | 5 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Mike Lowell | 3B | 107 | 895 | 82 | 174 | 9 | 14 | .966 | 2.57 | |
| Kevin Youkilis | 3B | 63 | 494 | 52 | 99 | 4 | 5 | .974 | 2.75 | |
| Nick Green | 3B | 9 | 19 | 4 | 4 | 1 | 0 | .889 | 3.77 | |
| Jed Lowrie | 3B | 4 | 10 | 1 | 4 | 0 | 0 | 1.000 | 4.50 | |
| Chris Woodward | 3B | 3 | 7 | 1 | 1 | 0 | 0 | 1.000 | 2.57 | |
| Gil Velazquez | 3B | 2 | 4 | 0 | 3 | 1 | 0 | .750 | 6.75 | |
| Rocco Baldelli | 3B | 1 | 3 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| George Kottaras | 3B | 1 | 4 | 0 | 2 | 0 | 0 | 1.000 | 4.50 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Nick Green | SS | 81 | 644 | 104 | 198 | 14 | 41 | .956 | 4.22 | |
| Alex Gonzalez | SS | 44 | 361 | 51 | 107 | 1 | 17 | .994 | 3.94 | |
| Julio Lugo | SS | 32 | 243 | 39 | 51 | 7 | 8 | .928 | 3.33 | |
| Jed Lowrie | SS | 26 | 163 | 22 | 52 | 1 | 16 | .987 | 4.08 | |
| Gil Velazquez | SS | 4 | 11 | 3 | 3 | 0 | 1 | 1.000 | 4.82 | |
| Chris Woodward | SS | 4 | 12 | 0 | 2 | 1 | 0 | .667 | 1.48 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Jason Bay | LF | 150 | 1279 | 310 | 15 | 0 | 2 | 1.000 | 2.29 | |
| Josh Reddick | LF | 12 | 81 | 20 | 0 | 0 | 0 | 1.000 | 2.22 | |
| Joey Gathright | LF | 7 | 12 | 4 | 0 | 0 | 0 | 1.000 | 3.00 | |
| Brian Anderson | LF | 4 | 11 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Nick Green | LF | 3 | 7 | 3 | 0 | 1 | 0 | .750 | 3.86 | |
| Jeff Bailey | LF | 2 | 13 | 2 | 0 | 0 | 0 | 1.000 | 1.38 | |
| Rocco Baldelli | LF | 2 | 11 | 3 | 0 | 0 | 0 | 1.000 | 2.45 | |
| Mark Kotsay | LF | 2 | 8 | 2 | 0 | 0 | 0 | 1.000 | 2.25 | |
| Kevin Youkilis | LF | 2 | 14 | 3 | 1 | 1 | 0 | .800 | 2.57 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Jacoby Ellsbury | CF | 153 | 1302 | 357 | 4 | 2 | 1 | .994 | 2.50 | |
| Rocco Baldelli | CF | 8 | 51 | 14 | 1 | 0 | 1 | 1.000 | 2.65 | |
| Brian Anderson | CF | 6 | 12 | 2 | 0 | 0 | 0 | 1.000 | 1.50 | |
| Joey Gathright | CF | 4 | 20 | 5 | 0 | 0 | 0 | 1.000 | 2.25 | |
| Mark Kotsay | CF | 4 | 28 | 5 | 0 | 0 | 0 | 1.000 | 1.61 | |
| Josh Reddick | CF | 2 | 8 | 1 | 0 | 0 | 0 | 1.000 | 1.13 | |
| Jon Van Every | CF | 2 | 15 | 2 | 0 | 0 | 0 | 1.000 | 1.20 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| J.D. Drew | RF | 131 | 1083 | 242 | 5 | 2 | 2 | .992 | 2.05 | |
| Rocco Baldelli | RF | 35 | 228 | 49 | 2 | 3 | 0 | .944 | 2.01 | |
| Brian Anderson | RF | 11 | 41 | 4 | 0 | 0 | 0 | 1.000 | 0.88 | |
| Josh Reddick | RF | 10 | 35 | 9 | 0 | 1 | 0 | .900 | 2.31 | |
| Mark Kotsay | RF | 4 | 8 | 1 | 0 | 0 | 0 | 1.000 | 1.10 | |
| Jon Van Every | RF | 4 | 14 | 4 | 0 | 0 | 0 | 1.000 | 2.55 | |
| Joey Gathright | RF | 2 | 11 | 4 | 0 | 0 | 0 | 1.000 | 3.27 | |
| Jeff Bailey | RF | 1 | 8 | 2 | 0 | 0 | 0 | 1.000 | 2.25 | |
| Chris Carter | RF | 1 | 6 | 2 | 0 | 0 | 0 | 1.000 | 3.00 | |
| Javier Lopez | RF | 1 | 0 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Ramon Ramirez | P | 70 | 69 | 7 | 4 | 1 | 1 | .917 | 1.43 | |
| Hideki Okajima | P | 68 | 61 | 3 | 6 | 1 | 0 | .900 | 1.33 | |
| Jonathan Papelbon | P | 66 | 68 | 1 | 4 | 1 | 0 | .833 | 0.66 | |
| Manny Delcarmen | P | 64 | 59 | 2 | 4 | 1 | 0 | .857 | 0.91 | |
| Takashi Saito | P | 56 | 55 | 3 | 7 | 1 | 1 | .909 | 1.63 | |
| Daniel Bard | P | 49 | 49 | 4 | 2 | 2 | 1 | .750 | 1.10 | |
| Josh Beckett | P | 32 | 212 | 11 | 14 | 2 | 2 | .926 | 1.06 | |
| Jon Lester | P | 32 | 203 | 7 | 24 | 2 | 1 | .939 | 1.37 | |
| Justin Masterson | P | 31 | 72 | 2 | 15 | 1 | 0 | .944 | 2.13 | |
| Brad Penny | P | 24 | 131 | 9 | 8 | 0 | 0 | 1.000 | 1.17 | |
| Tim Wakefield | P | 21 | 129 | 10 | 11 | 0 | 1 | 1.000 | 1.46 | |
| Clay Buchholz | P | 16 | 92 | 8 | 8 | 1 | 0 | .941 | 1.57 | |
| Billy Wagner | P | 15 | 13 | 0 | 2 | 0 | 0 | 1.000 | 1.36 | |
| Javier Lopez | P | 14 | 11 | 2 | 2 | 1 | 0 | .800 | 3.21 | |
| Daisuke Matsuzaka | P | 12 | 59 | 2 | 5 | 0 | 2 | 1.000 | 1.07 | |
| Hunter Jones | P | 11 | 12 | 0 | 1 | 0 | 0 | 1.000 | 0.74 | |
| Mike Bowden | P | 8 | 16 | 1 | 1 | 0 | 0 | 1.000 | 1.13 | |
| John Smoltz | P | 8 | 40 | 4 | 7 | 0 | 1 | 1.000 | 2.48 | |
| Paul Byrd | P | 7 | 34 | 2 | 5 | 0 | 1 | 1.000 | 1.85 | |
| Fernando Cabrera | P | 6 | 5 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Junichi Tazawa | P | 6 | 25 | 0 | 1 | 0 | 0 | 1.000 | 0.36 | |
| Dustin Richardson | P | 3 | 3 | 1 | 0 | 0 | 0 | 1.000 | 2.90 | |
| Enrique Gonzalez | P | 2 | 3 | 2 | 0 | 0 | 0 | 1.000 | 5.63 | |
| Dusty Brown | P | 1 | 1 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Nick Green | P | 1 | 2 | 0 | 2 | 0 | 0 | 1.000 | 9.00 | |
| Billy Traber | P | 1 | 3 | 0 | 1 | 0 | 0 | 1.000 | 2.81 | |
| Jon Van Every | P | 1 | 0 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| David Ortiz | DH | 138 | .000 | 0.00 | ||||||
| Mike Lowell | DH | 8 | .000 | 0.00 | ||||||
| Rocco Baldelli | DH | 4 | .000 | 0.00 | ||||||
| Jason Bay | DH | 1 | .000 | 0.00 | ||||||
| J.D. Drew | DH | 1 | .000 | 0.00 | ||||||
| Julio Lugo | DH | 1 | .000 | 0.00 |