| West | W | L | Pct | GB |
| LA Dodgers | 84 | 78 | .519 | -- |
| Arizona | 82 | 80 | .506 | 2.0 |
| Colorado | 74 | 88 | .457 | 10.0 |
| SF Giants | 72 | 90 | .444 | 12.0 |
| San Diego | 63 | 99 | .389 | 21.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2008-03-31 | Barry Zito | L | 30 | L 0-5 | @ LAN | 1 | 256 | L | 5.0 | 8 | 4 | 4 | 1 | 1 | 1 | 85 | 28 | 57 | 67% | 0-1 | 7.20 | 1.80 |
| 2008-04-01 | Matt Cain | R | 23 | L 2-3 | @ LAN | 1 | 71 | - | 5.2 | 3 | 0 | 0 | 0 | 4 | 5 | 116 | 46 | 70 | 60% | 0-0 | 0.00 | 1.17 |
| 2008-04-02 | Merkin Valdez | R | 26 | W 2-1 | @ LAN | 1 | 1 | - | 2.0 | 0 | 0 | 0 | 0 | 0 | 4 | 25 | 8 | 17 | 68% | 0-0 | 3.00 | 1.00 |
| 2008-04-04 | Jonathan Sanchez | L | 25 | L 4-13 | @ MIL | 1 | 9 | L | 4.0 | 7 | 7 | 7 | 1 | 2 | 8 | 93 | 38 | 55 | 59% | 0-1 | 15.75 | 2.25 |
| 2008-04-05 | Kevin Correia | R | 28 | L 4-5 | @ MIL | 1 | 28 | L | 6.0 | 6 | 4 | 4 | 1 | 3 | 4 | 87 | 33 | 54 | 62% | 0-1 | 6.00 | 1.50 |
| 2008-04-06 | Barry Zito | L | 30 | L 0-7 | @ MIL | 2 | 257 | L | 5.0 | 8 | 5 | 3 | 2 | 2 | 3 | 111 | 38 | 73 | 66% | 0-2 | 6.30 | 1.90 |
| 2008-04-07 | Matt Cain | R | 24 | W 4-8 | vs SDN | 2 | 72 | L | 4.1 | 7 | 5 | 4 | 1 | 5 | 5 | 97 | 41 | 56 | 58% | 0-1 | 3.60 | 1.90 |
| 2008-04-08 | Tim Lincecum | R | 24 | L 3-2 | vs SDN | 1 | 25 | - | 6.0 | 7 | 1 | 1 | 0 | 1 | 7 | 96 | 33 | 63 | 66% | 1-0 | 1.80 | 1.60 |
| 2008-04-09 | Jonathan Sanchez | L | 25 | L 1-0 | vs SDN | 2 | 10 | - | 6.0 | 3 | 0 | 0 | 0 | 2 | 10 | 101 | 36 | 65 | 64% | 0-1 | 6.30 | 1.40 |
| 2008-04-10 | Kevin Correia | R | 28 | L 5-1 | vs SLN | 2 | 29 | W | 7.2 | 5 | 0 | 0 | 0 | 2 | 4 | 100 | 39 | 61 | 61% | 1-1 | 2.57 | 1.14 |
| 2008-04-11 | Barry Zito | L | 30 | W 2-8 | vs SLN | 3 | 258 | L | 6.0 | 7 | 4 | 1 | 1 | 1 | 2 | 98 | 31 | 67 | 68% | 0-3 | 4.50 | 1.69 |
| 2008-04-12 | Matt Cain | R | 24 | W 7-8 | vs SLN | 3 | 73 | - | 6.2 | 3 | 2 | 2 | 0 | 3 | 5 | 95 | 39 | 56 | 59% | 0-1 | 3.18 | 1.47 |
| 2008-04-13 | Tim Lincecum | R | 24 | L 7-4 | vs SLN | 2 | 26 | W | 6.0 | 6 | 2 | 2 | 0 | 1 | 11 | 110 | 32 | 78 | 71% | 2-0 | 2.25 | 1.44 |
| 2008-04-14 | Jonathan Sanchez | L | 25 | L 5-4 | vs ARI | 3 | 11 | - | 5.0 | 6 | 4 | 3 | 1 | 2 | 3 | 99 | 43 | 56 | 57% | 0-1 | 6.00 | 1.47 |
| 2008-04-15 | Kevin Correia | R | 28 | W 2-8 | vs ARI | 3 | 30 | L | 6.0 | 5 | 5 | 5 | 2 | 3 | 6 | 83 | 29 | 54 | 65% | 1-2 | 4.05 | 1.20 |
| 2008-04-16 | Barry Zito | L | 30 | W 1-4 | vs ARI | 4 | 259 | L | 6.0 | 5 | 4 | 3 | 0 | 5 | 2 | 105 | 47 | 58 | 55% | 0-4 | 4.50 | 1.68 |
| 2008-04-18 | Matt Cain | R | 24 | L 1-11 | @ SLN | 4 | 74 | L | 3.2 | 8 | 9 | 9 | 2 | 3 | 4 | 78 | 32 | 46 | 59% | 0-2 | 6.75 | 1.80 |
| 2008-04-19 | Tim Lincecum | R | 24 | W 3-0 | @ SLN | 3 | 27 | W | 7.0 | 6 | 0 | 0 | 0 | 3 | 5 | 99 | 38 | 61 | 62% | 3-0 | 1.57 | 1.39 |
| 2008-04-20 | Jonathan Sanchez | L | 25 | W 8-2 | @ SLN | 4 | 12 | W | 5.0 | 2 | 0 | 0 | 0 | 4 | 5 | 101 | 42 | 59 | 58% | 1-1 | 4.50 | 1.40 |
| 2008-04-21 | Kevin Correia | R | 28 | L 2-4 | @ ARI | 4 | 31 | L | 6.0 | 8 | 3 | 3 | 2 | 2 | 2 | 92 | 38 | 54 | 59% | 1-3 | 4.15 | 1.31 |
| 2008-04-22 | Barry Zito | L | 30 | L 4-5 | @ ARI | 5 | 260 | L | 3.2 | 6 | 5 | 5 | 0 | 3 | 2 | 80 | 37 | 43 | 54% | 0-5 | 5.54 | 1.77 |
| 2008-04-23 | Matt Cain | R | 24 | W 3-2 | @ SDN | 5 | 75 | - | 7.0 | 5 | 1 | 1 | 0 | 3 | 7 | 97 | 41 | 56 | 58% | 0-2 | 5.33 | 1.63 |
| 2008-04-24 | Tim Lincecum | R | 24 | W 1-0 | @ SDN | 4 | 28 | W | 6.1 | 4 | 0 | 0 | 0 | 5 | 9 | 121 | 48 | 73 | 60% | 4-0 | 1.24 | 1.41 |
| 2008-04-25 | Jonathan Sanchez | L | 25 | L 3-1 | vs CIN | 5 | 13 | W | 8.0 | 4 | 1 | 1 | 1 | 1 | 10 | 106 | 34 | 72 | 68% | 2-1 | 3.54 | 1.18 |
| 2008-04-26 | Kevin Correia | R | 28 | W 9-10 | vs CIN | 5 | 32 | - | 0.1 | 1 | 1 | 1 | 0 | 0 | 0 | 6 | 1 | 5 | 83% | 1-3 | 4.50 | 1.35 |
| 2008-04-27 | Barry Zito | L | 30 | W 1-10 | vs CIN | 6 | 261 | L | 3.0 | 7 | 8 | 8 | 0 | 3 | 1 | 66 | 28 | 38 | 58% | 0-6 | 7.45 | 1.93 |
| 2008-04-28 | Matt Cain | R | 24 | L 4-0 | vs COL | 6 | 76 | W | 5.1 | 4 | 0 | 0 | 0 | 5 | 3 | 105 | 43 | 62 | 59% | 1-2 | 4.36 | 1.61 |
| 2008-04-29 | Tim Lincecum | R | 24 | W 2-3 | vs COL | 5 | 29 | L | 7.0 | 8 | 3 | 3 | 1 | 1 | 4 | 84 | 31 | 53 | 63% | 4-1 | 1.75 | 1.39 |
| 2008-04-30 | Jonathan Sanchez | L | 25 | L 3-2 | vs COL | 6 | 14 | - | 5.2 | 5 | 2 | 2 | 0 | 5 | 4 | 109 | 47 | 62 | 57% | 2-1 | 3.44 | 1.26 |
| 2008-05-02 | Pat Misch | L | 27 | L 5-6 | @ PHI | 1 | 5 | - | 4.0 | 5 | 4 | 4 | 2 | 2 | 4 | 71 | 26 | 45 | 63% | 0-0 | 5.40 | 1.30 |
| 2008-05-03 | Matt Cain | R | 24 | W 3-2 | @ PHI | 7 | 77 | - | 7.0 | 3 | 2 | 2 | 2 | 1 | 8 | 93 | 33 | 60 | 65% | 1-2 | 4.05 | 1.43 |
| 2008-05-04 | Tim Lincecum | R | 24 | L 5-6 | @ PHI | 6 | 30 | - | 6.0 | 6 | 4 | 0 | 0 | 2 | 5 | 112 | 49 | 63 | 56% | 4-1 | 1.50 | 1.38 |
| 2008-05-06 | Jonathan Sanchez | L | 25 | L 6-12 | @ PIT | 7 | 15 | L | 4.1 | 6 | 7 | 7 | 2 | 3 | 4 | 92 | 40 | 52 | 57% | 2-2 | 4.74 | 1.37 |
| 2008-05-07 | Barry Zito | L | 30 | L 1-3 | @ PIT | 7 | 262 | L | 5.0 | 5 | 2 | 2 | 1 | 2 | 5 | 99 | 41 | 58 | 59% | 0-7 | 6.88 | 1.85 |
| 2008-05-08 | Matt Cain | R | 24 | L 4-5 | @ PIT | 8 | 78 | L | 6.1 | 9 | 5 | 5 | 0 | 1 | 5 | 111 | 39 | 72 | 65% | 1-3 | 4.50 | 1.46 |
| 2008-05-09 | Pat Misch | L | 27 | W 4-7 | vs PHI | 2 | 6 | - | 6.0 | 6 | 4 | 4 | 1 | 3 | 4 | 89 | 33 | 56 | 63% | 0-0 | 5.63 | 1.38 |
| 2008-05-10 | Tim Lincecum | R | 24 | L 8-2 | vs PHI | 7 | 31 | W | 8.0 | 4 | 2 | 2 | 2 | 1 | 8 | 105 | 31 | 74 | 70% | 5-1 | 1.62 | 1.26 |
| 2008-05-11 | Jonathan Sanchez | L | 25 | L 4-3 | vs PHI | 8 | 16 | - | 4.1 | 4 | 3 | 3 | 0 | 5 | 2 | 89 | 42 | 47 | 53% | 2-2 | 4.93 | 1.45 |
| 2008-05-12 | Barry Zito | L | 30 | W 3-7 | vs HOU | 8 | 263 | - | 6.0 | 7 | 3 | 3 | 1 | 1 | 2 | 103 | 38 | 65 | 63% | 0-7 | 6.53 | 1.78 |
| 2008-05-13 | Matt Cain | R | 24 | L 4-2 | vs HOU | 9 | 79 | W | 8.0 | 7 | 2 | 2 | 1 | 4 | 5 | 111 | 40 | 71 | 64% | 2-3 | 4.17 | 1.44 |
| 2008-05-14 | Pat Misch | L | 27 | W 3-6 | vs HOU | 3 | 7 | - | 6.0 | 7 | 3 | 3 | 1 | 0 | 6 | 87 | 27 | 60 | 69% | 0-0 | 5.32 | 1.32 |
| 2008-05-15 | Tim Lincecum | R | 24 | W 7-8 | vs HOU | 8 | 32 | - | 6.0 | 5 | 3 | 3 | 0 | 3 | 10 | 104 | 40 | 64 | 62% | 5-1 | 1.93 | 1.27 |
| 2008-05-16 | Jonathan Sanchez | L | 25 | W 0-2 | vs CHA | 9 | 17 | L | 6.2 | 5 | 2 | 2 | 1 | 3 | 6 | 108 | 46 | 62 | 57% | 2-3 | 4.59 | 1.41 |
| 2008-05-17 | Barry Zito | L | 30 | W 1-3 | vs CHA | 9 | 264 | L | 5.0 | 8 | 2 | 2 | 0 | 6 | 4 | 115 | 51 | 64 | 56% | 0-8 | 6.20 | 1.89 |
| 2008-05-18 | Matt Cain | R | 24 | W 8-13 | vs CHA | 10 | 80 | - | 7.0 | 6 | 6 | 6 | 4 | 3 | 6 | 114 | 43 | 71 | 62% | 2-3 | 4.57 | 1.43 |
| 2008-05-19 | Pat Misch | L | 27 | L 3-4 | @ COL | 4 | 8 | - | 5.1 | 5 | 3 | 3 | 1 | 2 | 3 | 88 | 35 | 53 | 60% | 0-0 | 5.33 | 1.33 |
| 2008-05-20 | Tim Lincecum | R | 24 | W 6-5 | @ COL | 9 | 33 | W | 6.0 | 5 | 3 | 3 | 0 | 4 | 6 | 120 | 56 | 64 | 53% | 6-1 | 2.18 | 1.29 |
| 2008-05-21 | Jonathan Sanchez | L | 26 | W 3-2 | @ COL | 10 | 18 | - | 6.1 | 8 | 2 | 2 | 0 | 3 | 5 | 113 | 44 | 69 | 61% | 2-3 | 4.42 | 1.45 |
| 2008-05-23 | Barry Zito | L | 30 | W 8-2 | @ FLO | 10 | 265 | W | 6.1 | 3 | 1 | 1 | 0 | 4 | 5 | 109 | 50 | 59 | 54% | 1-8 | 5.65 | 1.80 |
| 2008-05-25 | Pat Misch | L | 27 | L 6-8 | @ FLO | 5 | 9 | L | 4.1 | 7 | 7 | 7 | 3 | 4 | 4 | 103 | 44 | 59 | 57% | 0-1 | 6.47 | 1.47 |
| 2008-05-25 | Matt Cain | R | 24 | L 4-5 | @ FLO | 11 | 81 | - | 6.0 | 5 | 2 | 2 | 1 | 2 | 6 | 98 | 37 | 61 | 62% | 2-3 | 4.43 | 1.40 |
| 2008-05-27 | Tim Lincecum | R | 24 | W 6-3 | @ ARI | 10 | 34 | W | 7.1 | 6 | 3 | 3 | 0 | 3 | 7 | 116 | 47 | 69 | 59% | 7-1 | 2.31 | 1.27 |
| 2008-05-28 | Jonathan Sanchez | L | 26 | W 11-3 | @ ARI | 11 | 19 | W | 6.0 | 6 | 2 | 2 | 0 | 3 | 6 | 106 | 45 | 61 | 58% | 3-3 | 4.28 | 1.46 |
| 2008-05-29 | Barry Zito | L | 30 | W 4-3 | @ ARI | 11 | 266 | - | 6.0 | 6 | 3 | 3 | 1 | 3 | 5 | 84 | 35 | 49 | 58% | 1-8 | 5.53 | 1.77 |
| 2008-05-30 | Matt Cain | R | 24 | W 3-7 | vs SDN | 12 | 82 | - | 7.0 | 7 | 3 | 3 | 0 | 1 | 6 | 99 | 31 | 68 | 69% | 2-3 | 4.38 | 1.38 |
| 2008-05-31 | Pat Misch | L | 27 | W 1-5 | vs SDN | 6 | 10 | L | 6.1 | 7 | 5 | 4 | 0 | 3 | 4 | 109 | 43 | 66 | 61% | 0-2 | 6.39 | 1.50 |
| 2008-06-01 | Tim Lincecum | R | 24 | L 4-3 | vs SDN | 11 | 35 | - | 7.0 | 4 | 1 | 1 | 0 | 4 | 2 | 100 | 42 | 58 | 58% | 7-1 | 2.22 | 1.26 |
| 2008-06-02 | Jonathan Sanchez | L | 26 | L 10-2 | vs NYN | 12 | 20 | W | 7.0 | 6 | 2 | 2 | 0 | 3 | 8 | 112 | 42 | 70 | 63% | 4-3 | 4.10 | 1.44 |
| 2008-06-03 | Barry Zito | L | 30 | W 6-9 | vs NYN | 12 | 267 | L | 4.1 | 7 | 6 | 5 | 0 | 5 | 1 | 96 | 42 | 54 | 56% | 1-9 | 5.90 | 1.85 |
| 2008-06-04 | Matt Cain | R | 24 | W 3-5 | vs NYN | 13 | 83 | L | 5.0 | 5 | 5 | 5 | 1 | 4 | 3 | 93 | 38 | 55 | 59% | 2-4 | 4.67 | 1.41 |
| 2008-06-06 | Tim Lincecum | R | 24 | W 10-1 | @ WAS | 12 | 36 | W | 7.0 | 5 | 1 | 1 | 0 | 0 | 5 | 81 | 28 | 53 | 65% | 8-1 | 2.14 | 1.21 |
| 2008-06-07 | Jonathan Sanchez | L | 26 | W 6-0 | @ WAS | 13 | 21 | W | 7.0 | 4 | 0 | 0 | 0 | 2 | 4 | 100 | 43 | 57 | 57% | 5-3 | 3.72 | 1.39 |
| 2008-06-08 | Barry Zito | L | 30 | W 6-3 | @ WAS | 13 | 268 | W | 5.0 | 7 | 3 | 3 | 1 | 4 | 2 | 82 | 32 | 50 | 61% | 2-9 | 5.86 | 1.88 |
| 2008-06-09 | Matt Cain | R | 24 | W 3-2 | @ WAS | 14 | 84 | W | 6.1 | 8 | 1 | 1 | 0 | 1 | 6 | 105 | 31 | 74 | 70% | 3-4 | 4.45 | 1.41 |
| 2008-06-10 | Pat Misch | L | 27 | L 5-10 | @ COL | 7 | 11 | L | 4.0 | 7 | 4 | 4 | 0 | 0 | 3 | 78 | 32 | 46 | 59% | 0-3 | 6.07 | 1.39 |
| 2008-06-11 | Tim Lincecum | R | 24 | L 0-1 | @ COL | 13 | 37 | - | 7.0 | 6 | 0 | 0 | 0 | 3 | 9 | 104 | 41 | 63 | 61% | 8-1 | 1.98 | 1.22 |
| 2008-06-12 | Jonathan Sanchez | L | 26 | W 10-7 | @ COL | 14 | 22 | W | 5.0 | 9 | 7 | 7 | 0 | 3 | 5 | 109 | 43 | 66 | 61% | 6-3 | 4.28 | 1.45 |
| 2008-06-13 | Barry Zito | L | 30 | W 1-5 | vs OAK | 14 | 269 | L | 5.2 | 6 | 4 | 4 | 0 | 4 | 3 | 102 | 38 | 64 | 63% | 2-10 | 5.88 | 1.86 |
| 2008-06-14 | Matt Cain | R | 24 | W 0-4 | vs OAK | 15 | 85 | L | 7.0 | 6 | 3 | 3 | 0 | 1 | 11 | 107 | 35 | 72 | 67% | 3-5 | 4.40 | 1.38 |
| 2008-06-15 | Kevin Correia | R | 28 | W 3-5 | vs OAK | 6 | 33 | L | 5.1 | 7 | 5 | 5 | 0 | 2 | 4 | 85 | 35 | 50 | 59% | 1-4 | 5.23 | 1.42 |
| 2008-06-16 | Tim Lincecum | R | 24 | L 8-6 | vs DET | 14 | 38 | - | 7.0 | 6 | 4 | 4 | 2 | 3 | 3 | 108 | 40 | 68 | 63% | 8-1 | 2.20 | 1.22 |
| 2008-06-17 | Jonathan Sanchez | L | 26 | W 1-5 | vs DET | 15 | 23 | L | 7.0 | 6 | 3 | 3 | 1 | 3 | 8 | 99 | 32 | 67 | 68% | 6-4 | 4.24 | 1.44 |
| 2008-06-18 | Barry Zito | L | 30 | W 2-7 | vs DET | 15 | 270 | L | 2.0 | 5 | 5 | 5 | 0 | 4 | 2 | 57 | 26 | 31 | 54% | 2-11 | 6.32 | 1.93 |
| 2008-06-20 | Matt Cain | R | 24 | W 9-4 | @ KCA | 16 | 86 | W | 8.0 | 5 | 4 | 3 | 0 | 1 | 8 | 112 | 33 | 79 | 71% | 4-5 | 4.32 | 1.33 |
| 2008-06-21 | Kevin Correia | R | 28 | L 3-5 | @ KCA | 7 | 34 | L | 5.0 | 6 | 3 | 3 | 0 | 4 | 2 | 98 | 34 | 64 | 65% | 1-5 | 5.25 | 1.50 |
| 2008-06-22 | Tim Lincecum | R | 24 | L 10-11 | @ KCA | 15 | 39 | - | 5.0 | 6 | 5 | 5 | 0 | 2 | 8 | 120 | 52 | 68 | 57% | 8-1 | 2.53 | 1.24 |
| 2008-06-24 | Jonathan Sanchez | L | 26 | W 3-2 | @ CLE | 16 | 24 | W | 7.2 | 5 | 1 | 1 | 0 | 2 | 8 | 118 | 46 | 72 | 61% | 7-4 | 3.98 | 1.39 |
| 2008-06-25 | Barry Zito | L | 30 | W 4-1 | @ CLE | 16 | 271 | W | 6.2 | 4 | 1 | 1 | 0 | 0 | 4 | 106 | 40 | 66 | 62% | 3-11 | 5.89 | 1.81 |
| 2008-06-26 | Matt Cain | R | 24 | L 1-4 | @ CLE | 17 | 87 | L | 5.0 | 8 | 4 | 4 | 0 | 2 | 4 | 99 | 34 | 65 | 66% | 4-6 | 4.46 | 1.36 |
| 2008-06-27 | Kevin Correia | R | 28 | L 1-4 | @ OAK | 8 | 35 | - | 5.0 | 4 | 1 | 1 | 0 | 2 | 4 | 109 | 46 | 63 | 58% | 1-5 | 4.83 | 1.46 |
| 2008-06-28 | Tim Lincecum | R | 24 | W 1-0 | @ OAK | 16 | 40 | W | 7.0 | 5 | 0 | 0 | 0 | 3 | 11 | 118 | 41 | 77 | 65% | 9-1 | 2.37 | 1.24 |
| 2008-06-29 | Jonathan Sanchez | L | 26 | W 11-1 | @ OAK | 17 | 25 | W | 7.0 | 4 | 1 | 1 | 1 | 1 | 6 | 102 | 35 | 67 | 66% | 8-4 | 3.79 | 1.34 |
| 2008-06-30 | Barry Zito | L | 30 | W 2-9 | vs CHN | 17 | 272 | L | 5.0 | 6 | 5 | 4 | 1 | 5 | 6 | 112 | 45 | 67 | 60% | 3-12 | 5.97 | 1.84 |
| 2008-07-01 | Matt Cain | R | 24 | L 2-1 | vs CHN | 18 | 88 | W | 8.0 | 2 | 0 | 0 | 0 | 3 | 10 | 113 | 42 | 71 | 63% | 5-6 | 4.14 | 1.31 |
| 2008-07-02 | Kevin Correia | R | 28 | W 5-6 | vs CHN | 9 | 36 | - | 6.1 | 7 | 4 | 4 | 1 | 3 | 4 | 103 | 38 | 65 | 63% | 1-5 | 4.88 | 1.46 |
| 2008-07-03 | Tim Lincecum | R | 24 | L 8-3 | vs CHN | 17 | 41 | W | 6.0 | 7 | 3 | 3 | 0 | 1 | 8 | 110 | 38 | 72 | 65% | 10-1 | 2.48 | 1.24 |
| 2008-07-04 | Jonathan Sanchez | L | 26 | W 7-10 | vs LAN | 18 | 26 | - | 5.0 | 5 | 3 | 3 | 1 | 3 | 7 | 109 | 40 | 69 | 63% | 8-4 | 3.87 | 1.36 |
| 2008-07-05 | Barry Zito | L | 30 | L 5-2 | vs LAN | 18 | 273 | W | 7.0 | 6 | 2 | 2 | 0 | 1 | 10 | 107 | 36 | 71 | 66% | 4-12 | 5.71 | 1.77 |
| 2008-07-06 | Matt Cain | R | 24 | W 3-5 | vs LAN | 19 | 89 | L | 6.0 | 8 | 5 | 5 | 0 | 3 | 5 | 92 | 33 | 59 | 64% | 5-7 | 4.31 | 1.34 |
| 2008-07-08 | Tim Lincecum | R | 24 | L 0-7 | @ NYN | 18 | 42 | L | 6.0 | 9 | 4 | 4 | 2 | 2 | 4 | 101 | 38 | 63 | 62% | 10-2 | 2.66 | 1.27 |
| 2008-07-09 | Jonathan Sanchez | L | 26 | L 0-5 | @ NYN | 19 | 27 | L | 4.0 | 3 | 3 | 3 | 1 | 3 | 6 | 83 | 34 | 49 | 59% | 8-5 | 3.97 | 1.36 |
| 2008-07-10 | Barry Zito | L | 30 | L 3-7 | @ NYN | 19 | 274 | - | 5.0 | 4 | 3 | 2 | 0 | 6 | 2 | 105 | 47 | 58 | 55% | 4-12 | 5.60 | 1.79 |
| 2008-07-11 | Matt Cain | R | 24 | L 1-3 | @ CHN | 20 | 90 | - | 7.0 | 3 | 0 | 0 | 0 | 3 | 9 | 119 | 41 | 78 | 66% | 5-7 | 4.07 | 1.31 |
| 2008-07-12 | Kevin Correia | R | 28 | L 7-8 | @ CHN | 10 | 37 | - | 3.2 | 9 | 7 | 7 | 1 | 4 | 4 | 79 | 33 | 46 | 58% | 1-5 | 5.77 | 1.60 |
| 2008-07-13 | Tim Lincecum | R | 24 | W 4-2 | @ CHN | 19 | 43 | W | 8.0 | 6 | 1 | 1 | 0 | 1 | 9 | 118 | 40 | 78 | 66% | 11-2 | 2.56 | 1.25 |
| 2008-07-18 | Matt Cain | R | 24 | W 1-9 | vs MIL | 21 | 91 | L | 6.0 | 7 | 4 | 3 | 0 | 5 | 5 | 110 | 44 | 66 | 60% | 5-8 | 4.09 | 1.34 |
| 2008-07-19 | Jonathan Sanchez | L | 26 | W 5-8 | vs MIL | 20 | 28 | - | 5.1 | 7 | 4 | 4 | 0 | 2 | 8 | 100 | 33 | 67 | 67% | 8-5 | 4.11 | 1.38 |
| 2008-07-20 | Tim Lincecum | R | 24 | W 4-7 | vs MIL | 20 | 44 | L | 6.0 | 6 | 5 | 5 | 2 | 4 | 8 | 121 | 43 | 78 | 64% | 11-3 | 2.78 | 1.26 |
| 2008-07-22 | Barry Zito | L | 30 | L 6-3 | vs WAS | 20 | 275 | W | 6.0 | 7 | 3 | 3 | 1 | 3 | 5 | 109 | 46 | 63 | 58% | 5-12 | 5.54 | 1.78 |
| 2008-07-23 | Kevin Correia | R | 28 | L 6-4 | vs WAS | 11 | 38 | - | 5.2 | 12 | 4 | 3 | 1 | 0 | 3 | 83 | 24 | 59 | 71% | 1-5 | 5.74 | 1.67 |
| 2008-07-24 | Matt Cain | R | 24 | L 1-0 | vs WAS | 22 | 92 | W | 9.0 | 4 | 0 | 0 | 0 | 0 | 4 | 112 | 32 | 80 | 71% | 6-8 | 3.83 | 1.28 |
| 2008-07-25 | Jonathan Sanchez | L | 26 | W 2-10 | vs ARI | 21 | 29 | L | 2.2 | 5 | 6 | 6 | 1 | 4 | 2 | 80 | 35 | 45 | 56% | 8-6 | 4.46 | 1.42 |
| 2008-07-26 | Tim Lincecum | R | 24 | W 3-5 | vs ARI | 21 | 45 | - | 7.0 | 7 | 2 | 2 | 0 | 0 | 13 | 108 | 35 | 73 | 68% | 11-3 | 2.77 | 1.25 |
| 2008-07-27 | Barry Zito | L | 30 | W 2-7 | vs ARI | 21 | 276 | L | 5.0 | 6 | 6 | 6 | 1 | 5 | 4 | 103 | 47 | 56 | 54% | 5-13 | 5.78 | 1.80 |
| 2008-07-28 | Kevin Correia | R | 28 | W 7-6 | @ LAN | 12 | 39 | W | 5.1 | 7 | 6 | 4 | 0 | 0 | 5 | 90 | 31 | 59 | 66% | 2-5 | 5.77 | 1.63 |
| 2008-07-29 | Matt Cain | R | 24 | L 0-2 | @ LAN | 23 | 93 | L | 7.0 | 8 | 2 | 1 | 0 | 0 | 8 | 133 | 35 | 98 | 74% | 6-9 | 3.71 | 1.28 |
| 2008-07-30 | Jonathan Sanchez | L | 26 | L 0-4 | @ LAN | 22 | 30 | L | 4.0 | 5 | 4 | 4 | 0 | 4 | 1 | 85 | 36 | 49 | 58% | 8-7 | 4.61 | 1.45 |
| 2008-08-01 | Tim Lincecum | R | 24 | W 3-2 | @ SDN | 22 | 46 | - | 7.0 | 3 | 1 | 1 | 0 | 3 | 11 | 113 | 43 | 70 | 62% | 11-3 | 2.70 | 1.23 |
| 2008-08-02 | Barry Zito | L | 30 | W 2-0 | @ SDN | 22 | 277 | W | 8.0 | 3 | 0 | 0 | 0 | 4 | 5 | 115 | 43 | 72 | 63% | 6-13 | 5.38 | 1.74 |
| 2008-08-03 | Kevin Correia | R | 28 | L 1-4 | @ SDN | 13 | 40 | L | 6.1 | 3 | 2 | 2 | 0 | 4 | 3 | 96 | 41 | 55 | 57% | 2-6 | 5.53 | 1.59 |
| 2008-08-04 | Matt Cain | R | 24 | L 4-2 | vs ATL | 24 | 94 | W | 6.2 | 5 | 1 | 1 | 0 | 5 | 6 | 106 | 44 | 62 | 58% | 7-9 | 3.60 | 1.28 |
| 2008-08-05 | Jonathan Sanchez | L | 26 | W 4-11 | vs ATL | 23 | 31 | L | 5.0 | 7 | 3 | 3 | 0 | 0 | 5 | 91 | 31 | 60 | 66% | 8-8 | 4.64 | 1.45 |
| 2008-08-06 | Tim Lincecum | R | 24 | L 3-2 | vs ATL | 23 | 47 | W | 8.0 | 5 | 2 | 2 | 0 | 4 | 8 | 117 | 45 | 72 | 62% | 12-3 | 2.68 | 1.23 |
| 2008-08-08 | Barry Zito | L | 30 | W 2-6 | vs LAN | 23 | 278 | L | 5.0 | 6 | 5 | 5 | 1 | 3 | 1 | 92 | 40 | 52 | 57% | 6-14 | 5.53 | 1.74 |
| 2008-08-09 | Kevin Correia | R | 28 | L 3-2 | vs LAN | 14 | 41 | - | 6.0 | 6 | 1 | 1 | 0 | 3 | 5 | 111 | 48 | 63 | 57% | 2-6 | 5.21 | 1.58 |
| 2008-08-10 | Matt Cain | R | 24 | L 5-4 | vs LAN | 25 | 95 | - | 7.0 | 6 | 4 | 4 | 0 | 4 | 4 | 124 | 45 | 79 | 64% | 7-9 | 3.67 | 1.29 |
| 2008-08-11 | Jonathan Sanchez | L | 26 | L 1-3 | @ HOU | 24 | 32 | L | 7.0 | 5 | 2 | 2 | 0 | 1 | 2 | 89 | 28 | 61 | 69% | 8-9 | 4.53 | 1.41 |
| 2008-08-12 | Tim Lincecum | R | 24 | L 4-12 | @ HOU | 24 | 48 | - | 4.1 | 1 | 2 | 1 | 0 | 2 | 7 | 75 | 28 | 47 | 63% | 12-3 | 2.67 | 1.22 |
| 2008-08-13 | Barry Zito | L | 30 | L 2-6 | @ HOU | 24 | 279 | L | 5.2 | 4 | 6 | 6 | 0 | 5 | 6 | 101 | 43 | 58 | 57% | 6-15 | 5.74 | 1.74 |
| 2008-08-14 | Kevin Correia | R | 28 | L 4-7 | @ HOU | 15 | 42 | - | 6.2 | 7 | 4 | 3 | 0 | 1 | 5 | 96 | 38 | 58 | 60% | 2-6 | 5.10 | 1.54 |
| 2008-08-15 | Matt Cain | R | 24 | W 5-1 | @ ATL | 26 | 96 | W | 7.0 | 6 | 1 | 1 | 0 | 1 | 5 | 115 | 40 | 75 | 65% | 8-9 | 3.57 | 1.28 |
| 2008-08-16 | Matt Palmer | R | 29 | L 5-11 | @ ATL | 1 | 1 | L | 2.1 | 7 | 6 | 6 | 0 | 4 | 0 | 66 | 31 | 35 | 53% | 0-1 | 27.00 | 5.50 |
| 2008-08-17 | Tim Lincecum | R | 24 | W 3-1 | @ ATL | 25 | 49 | W | 7.2 | 3 | 1 | 1 | 0 | 4 | 10 | 125 | 56 | 69 | 55% | 13-3 | 2.59 | 1.20 |
| 2008-08-18 | Barry Zito | L | 30 | W 5-0 | @ ATL | 25 | 280 | W | 7.0 | 5 | 0 | 0 | 0 | 2 | 3 | 112 | 47 | 65 | 58% | 7-15 | 5.44 | 1.70 |
| 2008-08-19 | Kevin Correia | R | 28 | W 0-6 | vs FLO | 16 | 43 | L | 4.2 | 7 | 5 | 3 | 0 | 3 | 0 | 99 | 45 | 54 | 55% | 2-7 | 5.17 | 1.59 |
| 2008-08-20 | Matt Cain | R | 24 | L 6-5 | vs FLO | 27 | 97 | - | 7.2 | 5 | 2 | 2 | 1 | 4 | 4 | 124 | 44 | 80 | 65% | 8-9 | 3.51 | 1.27 |
| 2008-08-21 | Matt Palmer | R | 29 | L 4-3 | vs FLO | 2 | 2 | - | 6.0 | 6 | 2 | 2 | 1 | 3 | 2 | 100 | 43 | 57 | 57% | 0-1 | 9.00 | 2.50 |
| 2008-08-22 | Tim Lincecum | R | 24 | L 5-0 | vs SDN | 26 | 50 | W | 8.0 | 4 | 0 | 0 | 0 | 3 | 8 | 115 | 42 | 73 | 63% | 14-3 | 2.48 | 1.19 |
| 2008-08-23 | Barry Zito | L | 30 | L 4-3 | vs SDN | 26 | 281 | W | 8.0 | 4 | 3 | 3 | 0 | 3 | 5 | 102 | 41 | 61 | 60% | 8-15 | 5.32 | 1.65 |
| 2008-08-24 | Kevin Correia | R | 28 | L 7-4 | vs SDN | 17 | 44 | W | 6.0 | 7 | 3 | 3 | 1 | 2 | 4 | 111 | 39 | 72 | 65% | 3-7 | 5.13 | 1.58 |
| 2008-08-25 | Matt Cain | R | 24 | W 2-4 | vs COL | 28 | 98 | L | 6.0 | 6 | 3 | 3 | 1 | 4 | 4 | 112 | 43 | 69 | 62% | 8-10 | 3.54 | 1.28 |
| 2008-08-26 | Matt Palmer | R | 29 | W 2-7 | vs COL | 3 | 3 | L | 4.1 | 4 | 5 | 4 | 0 | 6 | 1 | 86 | 39 | 47 | 55% | 0-2 | 8.31 | 2.31 |
| 2008-08-27 | Tim Lincecum | R | 24 | L 4-1 | vs COL | 27 | 51 | W | 7.2 | 5 | 1 | 1 | 0 | 3 | 10 | 129 | 48 | 81 | 63% | 15-3 | 2.43 | 1.18 |
| 2008-08-29 | Barry Zito | L | 30 | L 7-11 | @ CIN | 27 | 282 | L | 3.1 | 7 | 8 | 7 | 1 | 2 | 2 | 83 | 32 | 51 | 61% | 8-16 | 5.61 | 1.67 |
| 2008-08-30 | Kevin Correia | R | 28 | L 6-7 | @ CIN | 18 | 45 | - | 6.0 | 7 | 6 | 6 | 1 | 2 | 2 | 107 | 46 | 61 | 57% | 3-7 | 5.36 | 1.58 |
| 2008-08-31 | Matt Cain | R | 24 | L 3-9 | @ CIN | 29 | 99 | L | 5.0 | 8 | 5 | 5 | 0 | 5 | 3 | 114 | 49 | 65 | 57% | 8-11 | 3.69 | 1.32 |
| 2008-09-01 | Jonathan Sanchez | L | 26 | L 0-4 | @ COL | 25 | 33 | L | 7.0 | 3 | 3 | 3 | 0 | 3 | 6 | 112 | 45 | 67 | 60% | 8-10 | 4.50 | 1.39 |
| 2008-09-02 | Tim Lincecum | R | 24 | L 5-6 | @ COL | 28 | 52 | - | 5.0 | 5 | 5 | 5 | 1 | 2 | 6 | 102 | 42 | 60 | 59% | 15-3 | 2.61 | 1.19 |
| 2008-09-03 | Barry Zito | L | 30 | W 9-2 | @ COL | 28 | 283 | W | 8.0 | 4 | 2 | 2 | 1 | 2 | 5 | 123 | 48 | 75 | 61% | 9-16 | 5.44 | 1.62 |
| 2008-09-05 | Kevin Correia | R | 28 | W 0-7 | vs PIT | 19 | 46 | L | 4.1 | 7 | 3 | 3 | 0 | 2 | 0 | 74 | 26 | 48 | 65% | 3-8 | 5.37 | 1.59 |
| 2008-09-06 | Matt Cain | R | 24 | L 7-6 | vs PIT | 30 | 100 | - | 6.2 | 10 | 4 | 4 | 0 | 1 | 2 | 111 | 43 | 68 | 61% | 8-11 | 3.76 | 1.34 |
| 2008-09-07 | Jonathan Sanchez | L | 26 | L 11-6 | vs PIT | 26 | 34 | - | 3.0 | 5 | 3 | 2 | 0 | 2 | 5 | 78 | 30 | 48 | 62% | 8-10 | 4.53 | 1.41 |
| 2008-09-08 | Tim Lincecum | R | 24 | L 6-2 | vs ARI | 29 | 53 | W | 8.1 | 7 | 2 | 1 | 0 | 2 | 9 | 127 | 45 | 82 | 65% | 16-3 | 2.53 | 1.18 |
| 2008-09-09 | Barry Zito | L | 30 | L 5-4 | vs ARI | 29 | 284 | - | 6.0 | 5 | 2 | 2 | 0 | 3 | 9 | 111 | 50 | 61 | 55% | 9-16 | 5.34 | 1.61 |
| 2008-09-10 | Brad Hennessey | R | 29 | L 4-3 | vs ARI | 1 | 41 | - | 6.0 | 4 | 1 | 1 | 1 | 3 | 3 | 99 | 39 | 60 | 61% | 1-1 | 9.78 | 2.43 |
| 2008-09-11 | Matt Cain | R | 24 | L 3-11 | @ SDN | 31 | 101 | L | 3.1 | 9 | 6 | 6 | 2 | 1 | 3 | 81 | 27 | 54 | 67% | 8-12 | 3.95 | 1.36 |
| 2008-09-12 | Jonathan Sanchez | L | 26 | W 5-2 | @ SDN | 27 | 35 | W | 6.0 | 6 | 2 | 2 | 1 | 2 | 6 | 107 | 36 | 71 | 66% | 9-10 | 4.47 | 1.40 |
| 2008-09-13 | Tim Lincecum | R | 24 | W 7-0 | @ SDN | 30 | 54 | W | 9.0 | 4 | 0 | 0 | 0 | 3 | 12 | 141 | 54 | 87 | 62% | 17-3 | 2.42 | 1.16 |
| 2008-09-14 | Barry Zito | L | 30 | W 8-6 | @ SDN | 30 | 285 | - | 4.2 | 8 | 6 | 5 | 0 | 5 | 1 | 98 | 45 | 53 | 54% | 9-16 | 5.49 | 1.65 |
| 2008-09-15 | Brad Hennessey | R | 29 | L 1-3 | @ ARI | 2 | 42 | L | 8.0 | 8 | 3 | 3 | 2 | 0 | 2 | 98 | 34 | 64 | 65% | 1-2 | 8.13 | 2.06 |
| 2008-09-16 | Matt Cain | R | 24 | L 0-2 | @ ARI | 32 | 102 | L | 7.0 | 7 | 2 | 2 | 2 | 0 | 7 | 87 | 24 | 63 | 72% | 8-13 | 3.91 | 1.35 |
| 2008-09-17 | Jonathan Sanchez | L | 26 | L 6-7 | @ ARI | 28 | 36 | L | 3.2 | 6 | 6 | 6 | 1 | 3 | 4 | 82 | 29 | 53 | 65% | 9-11 | 4.70 | 1.43 |
| 2008-09-18 | Tim Lincecum | R | 24 | L 2-3 | @ ARI | 31 | 55 | L | 8.0 | 7 | 3 | 3 | 0 | 0 | 6 | 123 | 36 | 87 | 71% | 17-4 | 2.46 | 1.15 |
| 2008-09-19 | Barry Zito | L | 30 | W 7-1 | @ LAN | 31 | 286 | W | 7.2 | 6 | 1 | 1 | 1 | 1 | 6 | 118 | 35 | 83 | 70% | 10-16 | 5.28 | 1.62 |
| 2008-09-20 | Brad Hennessey | R | 29 | L 7-10 | @ LAN | 3 | 43 | - | 3.0 | 5 | 5 | 5 | 2 | 2 | 2 | 61 | 24 | 37 | 61% | 1-2 | 8.74 | 2.09 |
| 2008-09-21 | Matt Cain | R | 24 | W 1-0 | @ LAN | 33 | 103 | - | 6.0 | 5 | 0 | 0 | 0 | 4 | 4 | 108 | 35 | 73 | 68% | 8-13 | 3.80 | 1.35 |
| 2008-09-23 | Tim Lincecum | R | 24 | W 4-9 | vs COL | 32 | 56 | L | 4.1 | 6 | 6 | 6 | 1 | 5 | 9 | 102 | 42 | 60 | 59% | 17-5 | 2.66 | 1.18 |
| 2008-09-24 | Jonathan Sanchez | L | 26 | W 6-15 | vs COL | 29 | 37 | L | 3.1 | 7 | 7 | 7 | 1 | 1 | 3 | 72 | 30 | 42 | 58% | 9-12 | 5.01 | 1.45 |
| 2008-09-25 | Barry Zito | L | 30 | W 1-3 | vs COL | 32 | 287 | L | 8.0 | 6 | 3 | 2 | 1 | 4 | 6 | 111 | 41 | 70 | 63% | 10-17 | 5.15 | 1.60 |
| 2008-09-26 | Brad Hennessey | R | 29 | L 6-5 | vs LAN | 4 | 44 | - | 6.0 | 6 | 2 | 2 | 1 | 2 | 2 | 78 | 27 | 51 | 65% | 1-2 | 7.88 | 1.98 |
| 2008-09-27 | Matt Cain | R | 24 | W 1-2 | vs LAN | 34 | 104 | L | 7.0 | 8 | 2 | 2 | 1 | 4 | 6 | 113 | 43 | 70 | 62% | 8-14 | 3.76 | 1.36 |
| 2008-09-28 | Tim Lincecum | R | 24 | L 3-1 | vs LAN | 33 | 57 | W | 7.0 | 4 | 1 | 1 | 0 | 2 | 13 | 103 | 30 | 73 | 71% | 18-5 | 2.62 | 1.17 |