| West | W | L | Pct | GB |
| LA Dodgers | 84 | 78 | .519 | -- |
| Arizona | 82 | 80 | .506 | 2.0 |
| Colorado | 74 | 88 | .457 | 10.0 |
| SF Giants | 72 | 90 | .444 | 12.0 |
| San Diego | 63 | 99 | .389 | 21.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2008-03-31 | Brandon Webb | R | 29 | W 4-2 | @ CIN | 1 | 164 | W | 6.0 | 3 | 2 | 2 | 0 | 4 | 6 | 87 | 34 | 53 | 61% | 1-0 | 3.00 | 1.17 |
| 2008-04-02 | Dan Haren | R | 28 | L 5-6 | @ CIN | 1 | 122 | - | 6.0 | 4 | 3 | 3 | 2 | 1 | 4 | 95 | 38 | 57 | 60% | 0-0 | 4.50 | 0.83 |
| 2008-04-03 | Doug Davis | L | 33 | L 2-3 | @ CIN | 1 | 210 | L | 3.2 | 4 | 3 | 2 | 1 | 6 | 4 | 89 | 46 | 43 | 48% | 0-1 | 4.50 | 2.50 |
| 2008-04-04 | Micah Owings | R | 26 | W 8-1 | @ COL | 1 | 28 | W | 6.2 | 2 | 1 | 1 | 1 | 2 | 9 | 95 | 32 | 63 | 66% | 1-0 | 1.29 | 0.57 |
| 2008-04-05 | Brandon Webb | R | 29 | W 7-2 | @ COL | 2 | 165 | W | 7.0 | 5 | 2 | 1 | 1 | 1 | 5 | 96 | 33 | 63 | 66% | 2-0 | 2.08 | 1.00 |
| 2008-04-06 | Edgar Gonzalez | R | 25 | W 5-2 | @ COL | 1 | 30 | - | 5.0 | 6 | 1 | 1 | 0 | 0 | 4 | 93 | 31 | 62 | 67% | 0-0 | 1.80 | 1.20 |
| 2008-04-07 | Dan Haren | R | 28 | L 9-3 | vs LAN | 2 | 123 | W | 6.0 | 6 | 3 | 1 | 1 | 0 | 5 | 91 | 32 | 59 | 65% | 1-0 | 3.00 | 0.92 |
| 2008-04-08 | Doug Davis | L | 33 | L 10-5 | vs LAN | 2 | 211 | W | 6.0 | 6 | 2 | 2 | 0 | 2 | 7 | 102 | 41 | 61 | 60% | 1-1 | 3.60 | 1.80 |
| 2008-04-09 | Micah Owings | R | 26 | L 4-3 | vs LAN | 2 | 29 | W | 7.0 | 7 | 3 | 3 | 1 | 1 | 4 | 95 | 32 | 63 | 66% | 2-0 | 2.57 | 0.86 |
| 2008-04-11 | Brandon Webb | R | 29 | L 8-2 | vs COL | 3 | 166 | W | 8.0 | 4 | 2 | 2 | 0 | 1 | 6 | 104 | 39 | 65 | 63% | 3-0 | 2.14 | 0.86 |
| 2008-04-12 | Dan Haren | R | 28 | L 10-3 | vs COL | 3 | 124 | W | 6.0 | 5 | 1 | 1 | 0 | 2 | 7 | 93 | 29 | 64 | 69% | 2-0 | 2.50 | 1.00 |
| 2008-04-13 | Edgar Gonzalez | R | 25 | W 5-13 | vs COL | 2 | 31 | L | 3.0 | 5 | 3 | 3 | 1 | 2 | 1 | 52 | 23 | 29 | 56% | 0-1 | 4.50 | 1.63 |
| 2008-04-14 | Randy Johnson | L | 45 | L 4-5 | @ SFN | 1 | 557 | - | 5.0 | 3 | 3 | 0 | 0 | 4 | 7 | 92 | 42 | 50 | 54% | 0-0 | 0.00 | 1.40 |
| 2008-04-15 | Micah Owings | R | 26 | W 8-2 | @ SFN | 3 | 30 | W | 6.0 | 3 | 1 | 1 | 0 | 2 | 6 | 98 | 33 | 65 | 66% | 3-0 | 2.25 | 0.85 |
| 2008-04-16 | Brandon Webb | R | 29 | W 4-1 | @ SFN | 4 | 167 | W | 8.0 | 3 | 1 | 1 | 0 | 2 | 5 | 103 | 38 | 65 | 63% | 4-0 | 1.86 | 0.79 |
| 2008-04-18 | Dan Haren | R | 28 | L 9-0 | vs SDN | 4 | 125 | W | 7.0 | 3 | 0 | 0 | 0 | 1 | 3 | 99 | 32 | 67 | 68% | 3-0 | 1.80 | 0.88 |
| 2008-04-19 | Edgar Gonzalez | R | 25 | L 10-3 | vs SDN | 3 | 32 | - | 6.0 | 4 | 3 | 3 | 2 | 4 | 3 | 93 | 39 | 54 | 58% | 0-1 | 4.50 | 1.50 |
| 2008-04-20 | Randy Johnson | L | 45 | W 4-9 | vs SDN | 2 | 558 | L | 5.2 | 6 | 6 | 4 | 1 | 3 | 6 | 102 | 42 | 60 | 59% | 0-1 | 3.27 | 1.45 |
| 2008-04-21 | Micah Owings | R | 26 | L 4-2 | vs SFN | 4 | 31 | W | 6.1 | 5 | 2 | 2 | 1 | 1 | 4 | 96 | 34 | 62 | 65% | 4-0 | 2.42 | 0.88 |
| 2008-04-22 | Brandon Webb | R | 29 | L 5-4 | vs SFN | 5 | 168 | W | 6.0 | 9 | 3 | 3 | 0 | 2 | 7 | 95 | 31 | 64 | 67% | 5-0 | 2.31 | 0.97 |
| 2008-04-23 | Dan Haren | R | 28 | L 3-8 | @ LAN | 5 | 126 | L | 4.2 | 9 | 6 | 5 | 0 | 2 | 5 | 111 | 47 | 64 | 58% | 3-1 | 3.00 | 1.10 |
| 2008-04-24 | Edgar Gonzalez | R | 25 | W 6-4 | @ LAN | 4 | 33 | W | 5.1 | 7 | 3 | 3 | 0 | 2 | 1 | 92 | 41 | 51 | 55% | 1-1 | 4.74 | 1.58 |
| 2008-04-25 | Randy Johnson | L | 45 | W 5-1 | @ SDN | 3 | 559 | W | 6.0 | 3 | 1 | 1 | 0 | 2 | 7 | 93 | 38 | 55 | 59% | 1-1 | 2.65 | 1.24 |
| 2008-04-26 | Micah Owings | R | 26 | L 7-8 | @ SDN | 5 | 32 | - | 5.0 | 5 | 5 | 5 | 1 | 3 | 5 | 92 | 35 | 57 | 62% | 4-0 | 3.48 | 1.00 |
| 2008-04-27 | Brandon Webb | R | 29 | W 2-1 | @ SDN | 6 | 169 | W | 6.0 | 5 | 1 | 0 | 0 | 4 | 5 | 96 | 38 | 58 | 60% | 6-0 | 1.98 | 1.05 |
| 2008-04-28 | Dan Haren | R | 28 | L 5-3 | vs HOU | 6 | 127 | W | 7.2 | 5 | 3 | 3 | 0 | 1 | 5 | 103 | 32 | 71 | 69% | 4-1 | 3.16 | 1.05 |
| 2008-04-29 | Edgar Gonzalez | R | 25 | W 4-6 | vs HOU | 5 | 34 | L | 2.2 | 8 | 6 | 6 | 0 | 2 | 2 | 72 | 27 | 45 | 63% | 1-2 | 6.55 | 1.82 |
| 2008-04-30 | Randy Johnson | L | 45 | L 8-7 | vs HOU | 4 | 560 | - | 4.0 | 9 | 6 | 6 | 1 | 0 | 2 | 72 | 26 | 46 | 64% | 1-1 | 4.71 | 1.43 |
| 2008-05-02 | Micah Owings | R | 26 | W 2-7 | vs NYN | 6 | 33 | L | 5.2 | 10 | 7 | 6 | 2 | 3 | 2 | 107 | 41 | 66 | 62% | 4-1 | 4.38 | 1.19 |
| 2008-05-03 | Brandon Webb | R | 29 | L 10-4 | vs NYN | 7 | 170 | W | 6.0 | 5 | 4 | 4 | 1 | 2 | 3 | 102 | 42 | 60 | 59% | 7-0 | 2.49 | 1.06 |
| 2008-05-04 | Dan Haren | R | 28 | W 2-5 | vs NYN | 7 | 128 | - | 6.0 | 3 | 2 | 2 | 1 | 1 | 7 | 83 | 33 | 50 | 60% | 4-1 | 3.14 | 1.00 |
| 2008-05-05 | Max Scherzer | R | 24 | W 4-11 | vs PHI | 1 | 1 | L | 4.0 | 8 | 5 | 5 | 0 | 2 | 5 | 92 | 34 | 58 | 63% | 0-1 | 5.63 | 1.25 |
| 2008-05-06 | Randy Johnson | L | 45 | L 6-4 | vs PHI | 5 | 561 | W | 6.0 | 6 | 4 | 4 | 2 | 2 | 6 | 97 | 34 | 63 | 65% | 2-1 | 5.00 | 1.41 |
| 2008-05-07 | Micah Owings | R | 26 | W 4-5 | vs PHI | 7 | 34 | - | 7.0 | 4 | 3 | 3 | 1 | 2 | 7 | 95 | 32 | 63 | 66% | 4-1 | 4.30 | 1.14 |
| 2008-05-08 | Brandon Webb | R | 29 | L 8-3 | vs PHI | 8 | 171 | W | 9.0 | 6 | 3 | 2 | 0 | 0 | 4 | 104 | 33 | 71 | 68% | 8-0 | 2.41 | 1.00 |
| 2008-05-09 | Dan Haren | R | 28 | L 1-3 | @ CHN | 8 | 129 | L | 7.0 | 5 | 2 | 2 | 0 | 2 | 5 | 109 | 39 | 70 | 64% | 4-2 | 3.06 | 1.00 |
| 2008-05-10 | Max Scherzer | R | 24 | L 2-7 | @ CHN | 2 | 2 | - | 6.0 | 5 | 1 | 0 | 0 | 1 | 6 | 77 | 29 | 48 | 62% | 0-1 | 3.21 | 1.14 |
| 2008-05-11 | Edgar Gonzalez | R | 25 | L 4-6 | @ CHN | 6 | 35 | - | 5.0 | 5 | 2 | 2 | 1 | 2 | 3 | 89 | 30 | 59 | 66% | 1-2 | 6.60 | 1.87 |
| 2008-05-13 | Randy Johnson | L | 45 | L 8-4 | vs COL | 6 | 562 | W | 5.0 | 9 | 4 | 4 | 1 | 0 | 4 | 89 | 27 | 62 | 70% | 3-1 | 5.34 | 1.47 |
| 2008-05-14 | Micah Owings | R | 26 | L 4-3 | vs COL | 8 | 35 | W | 6.0 | 5 | 0 | 0 | 0 | 2 | 5 | 100 | 35 | 65 | 65% | 5-1 | 3.78 | 1.14 |
| 2008-05-15 | Brandon Webb | R | 29 | L 8-5 | vs COL | 9 | 172 | W | 7.1 | 6 | 3 | 3 | 0 | 1 | 8 | 110 | 34 | 76 | 69% | 9-0 | 2.57 | 1.00 |
| 2008-05-16 | Dan Haren | R | 28 | L 4-3 | vs DET | 9 | 130 | W | 7.0 | 6 | 3 | 3 | 1 | 0 | 4 | 104 | 31 | 73 | 70% | 5-2 | 3.16 | 0.98 |
| 2008-05-17 | Max Scherzer | R | 24 | W 2-3 | vs DET | 3 | 3 | L | 5.0 | 3 | 2 | 0 | 0 | 4 | 5 | 101 | 43 | 58 | 57% | 0-2 | 2.37 | 1.21 |
| 2008-05-18 | Randy Johnson | L | 45 | L 4-0 | vs DET | 7 | 563 | W | 7.0 | 6 | 0 | 0 | 0 | 1 | 5 | 98 | 31 | 67 | 68% | 4-1 | 4.38 | 1.38 |
| 2008-05-20 | Micah Owings | R | 26 | L 2-3 | @ FLO | 9 | 36 | L | 7.0 | 7 | 3 | 3 | 1 | 2 | 10 | 112 | 40 | 72 | 64% | 5-2 | 3.79 | 1.16 |
| 2008-05-21 | Brandon Webb | R | 29 | L 1-3 | @ FLO | 10 | 173 | L | 7.0 | 6 | 3 | 3 | 1 | 0 | 7 | 98 | 36 | 62 | 63% | 9-1 | 2.70 | 0.99 |
| 2008-05-22 | Dan Haren | R | 28 | L 0-4 | @ FLO | 10 | 131 | L | 6.1 | 8 | 4 | 4 | 0 | 0 | 8 | 92 | 27 | 65 | 71% | 5-3 | 3.38 | 1.00 |
| 2008-05-23 | Doug Davis | L | 33 | W 11-1 | @ ATL | 3 | 212 | W | 7.0 | 5 | 1 | 1 | 0 | 2 | 4 | 89 | 36 | 53 | 60% | 2-1 | 2.65 | 1.47 |
| 2008-05-24 | Randy Johnson | L | 45 | L 1-3 | @ ATL | 8 | 564 | - | 6.0 | 5 | 1 | 1 | 0 | 0 | 10 | 82 | 24 | 58 | 71% | 4-1 | 4.00 | 1.31 |
| 2008-05-25 | Micah Owings | R | 26 | W 9-3 | @ ATL | 10 | 37 | W | 6.0 | 6 | 3 | 2 | 0 | 2 | 3 | 104 | 35 | 69 | 66% | 6-2 | 3.71 | 1.17 |
| 2008-05-26 | Brandon Webb | R | 29 | L 3-7 | @ ATL | 11 | 174 | L | 4.1 | 10 | 7 | 4 | 1 | 3 | 8 | 99 | 35 | 64 | 65% | 9-2 | 3.00 | 1.09 |
| 2008-05-27 | Dan Haren | R | 28 | W 3-6 | vs SFN | 11 | 132 | L | 6.0 | 9 | 5 | 5 | 2 | 1 | 7 | 96 | 35 | 61 | 64% | 5-4 | 3.73 | 1.06 |
| 2008-05-28 | Doug Davis | L | 33 | W 3-11 | vs SFN | 4 | 213 | L | 5.0 | 9 | 6 | 6 | 1 | 3 | 5 | 98 | 45 | 53 | 54% | 2-2 | 4.50 | 1.68 |
| 2008-05-29 | Randy Johnson | L | 45 | W 3-4 | vs SFN | 9 | 565 | - | 7.0 | 6 | 2 | 2 | 1 | 2 | 9 | 103 | 35 | 68 | 66% | 4-1 | 3.81 | 1.29 |
| 2008-05-30 | Micah Owings | R | 26 | W 4-7 | vs WAS | 11 | 38 | L | 6.1 | 8 | 6 | 6 | 1 | 0 | 6 | 81 | 21 | 60 | 74% | 6-3 | 4.17 | 1.19 |
| 2008-05-31 | Brandon Webb | R | 29 | L 4-0 | vs WAS | 12 | 175 | W | 9.0 | 6 | 0 | 0 | 0 | 0 | 8 | 112 | 40 | 72 | 64% | 10-2 | 2.68 | 1.05 |
| 2008-06-01 | Dan Haren | R | 28 | L 5-0 | vs WAS | 12 | 133 | W | 7.0 | 4 | 0 | 0 | 0 | 3 | 5 | 105 | 41 | 64 | 61% | 6-4 | 3.39 | 1.05 |
| 2008-06-02 | Doug Davis | L | 33 | L 3-4 | @ MIL | 5 | 214 | - | 6.0 | 6 | 3 | 1 | 0 | 2 | 3 | 102 | 34 | 68 | 67% | 2-2 | 3.86 | 1.61 |
| 2008-06-03 | Randy Johnson | L | 45 | L 1-7 | @ MIL | 10 | 566 | L | 6.1 | 6 | 4 | 3 | 1 | 1 | 8 | 102 | 31 | 71 | 70% | 4-2 | 3.88 | 1.28 |
| 2008-06-04 | Micah Owings | R | 26 | L 1-10 | @ MIL | 12 | 39 | L | 3.0 | 8 | 5 | 4 | 0 | 1 | 3 | 69 | 24 | 45 | 65% | 6-4 | 4.50 | 1.26 |
| 2008-06-06 | Brandon Webb | R | 29 | W 3-1 | @ PIT | 13 | 176 | W | 7.0 | 3 | 1 | 1 | 0 | 0 | 3 | 98 | 35 | 63 | 64% | 11-2 | 2.57 | 1.00 |
| 2008-06-07 | Dan Haren | R | 28 | W 4-3 | @ PIT | 13 | 134 | - | 7.0 | 5 | 3 | 3 | 2 | 1 | 6 | 94 | 39 | 55 | 59% | 6-4 | 3.43 | 1.04 |
| 2008-06-08 | Doug Davis | L | 33 | L 4-6 | @ PIT | 6 | 215 | L | 3.2 | 7 | 5 | 5 | 0 | 4 | 0 | 90 | 36 | 54 | 60% | 2-3 | 4.94 | 1.81 |
| 2008-06-09 | Randy Johnson | L | 45 | L 3-5 | @ PIT | 11 | 567 | L | 5.2 | 6 | 5 | 4 | 0 | 5 | 3 | 108 | 44 | 64 | 59% | 4-3 | 4.08 | 1.33 |
| 2008-06-10 | Micah Owings | R | 26 | W 9-5 | @ NYN | 13 | 40 | - | 4.1 | 8 | 5 | 4 | 1 | 3 | 2 | 87 | 36 | 51 | 59% | 6-4 | 4.74 | 1.34 |
| 2008-06-11 | Brandon Webb | R | 29 | L 3-5 | @ NYN | 14 | 177 | - | 5.0 | 4 | 3 | 1 | 0 | 0 | 4 | 58 | 18 | 40 | 69% | 11-2 | 2.53 | 0.99 |
| 2008-06-12 | Dan Haren | R | 28 | W 5-4 | @ NYN | 14 | 135 | - | 6.0 | 5 | 2 | 2 | 1 | 0 | 5 | 99 | 30 | 69 | 70% | 6-4 | 3.40 | 1.02 |
| 2008-06-13 | Doug Davis | L | 33 | L 1-0 | vs KCA | 7 | 216 | - | 7.0 | 6 | 0 | 0 | 0 | 4 | 7 | 103 | 44 | 59 | 57% | 2-3 | 4.03 | 1.74 |
| 2008-06-14 | Randy Johnson | L | 45 | W 3-12 | vs KCA | 12 | 568 | L | 4.1 | 10 | 8 | 7 | 1 | 0 | 3 | 79 | 24 | 55 | 70% | 4-4 | 4.76 | 1.40 |
| 2008-06-15 | Micah Owings | R | 26 | W 3-8 | vs KCA | 14 | 41 | L | 5.1 | 8 | 7 | 7 | 1 | 2 | 4 | 97 | 36 | 61 | 63% | 6-5 | 5.16 | 1.37 |
| 2008-06-17 | Brandon Webb | R | 29 | W 1-15 | vs OAK | 15 | 178 | L | 3.1 | 9 | 7 | 7 | 2 | 5 | 3 | 83 | 35 | 48 | 58% | 11-3 | 3.09 | 1.10 |
| 2008-06-18 | Dan Haren | R | 28 | L 11-1 | vs OAK | 15 | 136 | W | 7.0 | 4 | 1 | 1 | 0 | 1 | 8 | 112 | 41 | 71 | 63% | 7-4 | 3.25 | 1.00 |
| 2008-06-19 | Doug Davis | L | 33 | L 2-1 | vs OAK | 8 | 217 | - | 6.0 | 3 | 1 | 1 | 0 | 2 | 8 | 102 | 41 | 61 | 60% | 2-3 | 3.68 | 1.61 |
| 2008-06-20 | Randy Johnson | L | 45 | L 2-7 | @ MIN | 13 | 569 | L | 8.0 | 11 | 7 | 7 | 1 | 2 | 1 | 110 | 38 | 72 | 65% | 4-5 | 5.09 | 1.42 |
| 2008-06-21 | Micah Owings | R | 26 | L 1-6 | @ MIN | 15 | 42 | L | 6.1 | 5 | 3 | 3 | 0 | 1 | 3 | 97 | 35 | 62 | 64% | 6-6 | 5.11 | 1.34 |
| 2008-06-22 | Brandon Webb | R | 29 | L 3-5 | @ MIN | 16 | 179 | L | 7.0 | 8 | 5 | 4 | 0 | 1 | 4 | 100 | 34 | 66 | 66% | 11-4 | 3.23 | 1.11 |
| 2008-06-23 | Dan Haren | R | 28 | W 2-1 | @ BOS | 16 | 137 | W | 7.0 | 2 | 0 | 0 | 0 | 1 | 5 | 98 | 37 | 61 | 62% | 8-4 | 3.03 | 0.96 |
| 2008-06-24 | Doug Davis | L | 33 | L 4-5 | @ BOS | 9 | 218 | - | 7.0 | 7 | 3 | 3 | 1 | 1 | 6 | 98 | 33 | 65 | 66% | 2-3 | 3.71 | 1.55 |
| 2008-06-25 | Randy Johnson | L | 45 | L 0-5 | @ BOS | 14 | 570 | L | 6.0 | 8 | 2 | 2 | 0 | 2 | 5 | 109 | 41 | 68 | 62% | 4-6 | 4.94 | 1.44 |
| 2008-06-27 | Micah Owings | R | 26 | L 1-3 | @ FLO | 16 | 43 | L | 4.0 | 4 | 3 | 3 | 1 | 2 | 6 | 88 | 30 | 58 | 66% | 6-7 | 5.18 | 1.35 |
| 2008-06-28 | Brandon Webb | R | 29 | W 6-2 | @ FLO | 17 | 180 | W | 6.0 | 5 | 2 | 2 | 0 | 3 | 8 | 114 | 44 | 70 | 61% | 12-4 | 3.21 | 1.13 |
| 2008-06-29 | Dan Haren | R | 28 | L 3-4 | @ FLO | 17 | 138 | - | 7.0 | 5 | 1 | 0 | 0 | 2 | 7 | 105 | 37 | 68 | 65% | 8-4 | 2.84 | 0.96 |
| 2008-06-30 | Doug Davis | L | 33 | L 6-3 | vs MIL | 10 | 219 | W | 5.2 | 5 | 3 | 3 | 0 | 4 | 3 | 100 | 41 | 59 | 59% | 3-3 | 3.79 | 1.54 |
| 2008-07-01 | Randy Johnson | L | 45 | W 6-8 | vs MIL | 15 | 571 | L | 3.2 | 8 | 7 | 7 | 3 | 3 | 6 | 90 | 36 | 54 | 60% | 4-7 | 5.44 | 1.50 |
| 2008-07-02 | Yusmeiro Petit | R | 24 | W 3-4 | vs MIL | 1 | 12 | - | 6.0 | 2 | 1 | 1 | 0 | 0 | 4 | 77 | 24 | 53 | 69% | 0-1 | 3.21 | 0.79 |
| 2008-07-03 | Brandon Webb | R | 29 | L 6-5 | vs MIL | 18 | 181 | - | 6.0 | 9 | 5 | 5 | 2 | 2 | 6 | 91 | 32 | 59 | 65% | 12-4 | 3.43 | 1.16 |
| 2008-07-04 | Dan Haren | R | 28 | W 1-5 | vs SDN | 18 | 139 | L | 7.0 | 7 | 2 | 2 | 0 | 1 | 7 | 115 | 43 | 72 | 63% | 8-5 | 2.82 | 0.97 |
| 2008-07-05 | Doug Davis | L | 33 | W 2-4 | vs SDN | 11 | 220 | L | 8.0 | 7 | 3 | 3 | 2 | 1 | 7 | 120 | 49 | 71 | 59% | 3-4 | 3.74 | 1.48 |
| 2008-07-06 | Randy Johnson | L | 45 | L 3-2 | vs SDN | 16 | 572 | W | 6.1 | 3 | 1 | 1 | 1 | 0 | 10 | 103 | 33 | 70 | 68% | 5-7 | 5.18 | 1.43 |
| 2008-07-08 | Brandon Webb | R | 29 | W 2-0 | @ WAS | 19 | 182 | W | 6.0 | 6 | 0 | 0 | 0 | 2 | 6 | 112 | 47 | 65 | 58% | 13-4 | 3.27 | 1.17 |
| 2008-07-09 | Micah Owings | R | 26 | L 0-5 | @ WAS | 17 | 44 | L | 5.2 | 1 | 3 | 3 | 0 | 5 | 2 | 89 | 43 | 46 | 52% | 6-8 | 5.14 | 1.33 |
| 2008-07-10 | Dan Haren | R | 28 | W 7-5 | @ WAS | 19 | 140 | - | 8.0 | 3 | 2 | 1 | 0 | 2 | 9 | 113 | 34 | 79 | 70% | 8-5 | 2.71 | 0.95 |
| 2008-07-11 | Doug Davis | L | 33 | L 5-6 | @ PHI | 12 | 221 | - | 6.0 | 5 | 3 | 3 | 1 | 4 | 4 | 106 | 44 | 62 | 58% | 3-4 | 3.80 | 1.48 |
| 2008-07-12 | Randy Johnson | L | 45 | W 10-4 | @ PHI | 17 | 573 | W | 6.0 | 5 | 4 | 4 | 2 | 1 | 3 | 84 | 23 | 61 | 73% | 6-7 | 5.23 | 1.41 |
| 2008-07-13 | Brandon Webb | R | 29 | L 3-6 | @ PHI | 20 | 183 | - | 7.0 | 7 | 2 | 2 | 0 | 0 | 6 | 117 | 40 | 77 | 66% | 13-4 | 3.23 | 1.16 |
| 2008-07-18 | Doug Davis | L | 33 | W 7-8 | vs LAN | 13 | 222 | - | 3.0 | 5 | 5 | 4 | 1 | 3 | 3 | 86 | 39 | 47 | 55% | 3-4 | 4.14 | 1.53 |
| 2008-07-19 | Dan Haren | R | 28 | L 3-2 | vs LAN | 20 | 141 | W | 7.0 | 4 | 0 | 0 | 0 | 2 | 7 | 102 | 37 | 65 | 64% | 9-5 | 2.57 | 0.95 |
| 2008-07-20 | Brandon Webb | R | 29 | W 5-6 | vs LAN | 21 | 184 | - | 8.0 | 6 | 1 | 1 | 0 | 3 | 4 | 108 | 44 | 64 | 59% | 13-4 | 3.11 | 1.16 |
| 2008-07-21 | Randy Johnson | L | 45 | L 2-0 | vs CHN | 18 | 574 | W | 7.0 | 2 | 0 | 0 | 0 | 1 | 4 | 85 | 27 | 58 | 68% | 7-7 | 4.89 | 1.34 |
| 2008-07-22 | Yusmeiro Petit | R | 24 | L 9-2 | vs CHN | 2 | 13 | W | 5.0 | 3 | 1 | 1 | 0 | 4 | 3 | 85 | 36 | 49 | 58% | 1-1 | 2.74 | 0.87 |
| 2008-07-23 | Doug Davis | L | 33 | W 6-10 | vs CHN | 14 | 223 | L | 7.0 | 5 | 4 | 4 | 1 | 2 | 6 | 101 | 37 | 64 | 63% | 3-5 | 4.22 | 1.48 |
| 2008-07-25 | Dan Haren | R | 28 | W 10-2 | @ SFN | 21 | 142 | W | 8.0 | 9 | 2 | 2 | 0 | 0 | 9 | 99 | 28 | 71 | 72% | 10-5 | 2.55 | 0.96 |
| 2008-07-26 | Brandon Webb | R | 29 | W 5-3 | @ SFN | 22 | 185 | W | 7.0 | 4 | 3 | 3 | 0 | 2 | 8 | 117 | 42 | 75 | 64% | 14-4 | 3.14 | 1.14 |
| 2008-07-27 | Randy Johnson | L | 45 | W 7-2 | @ SFN | 19 | 575 | W | 7.0 | 9 | 0 | 0 | 0 | 0 | 2 | 97 | 30 | 67 | 69% | 8-7 | 4.58 | 1.34 |
| 2008-07-28 | Micah Owings | R | 26 | L 5-8 | @ SDN | 18 | 45 | L | 3.0 | 6 | 8 | 8 | 2 | 2 | 2 | 67 | 30 | 37 | 55% | 6-9 | 5.91 | 1.38 |
| 2008-07-29 | Doug Davis | L | 33 | W 3-0 | @ SDN | 15 | 224 | W | 7.2 | 2 | 0 | 0 | 0 | 2 | 8 | 122 | 48 | 74 | 61% | 4-5 | 3.84 | 1.39 |
| 2008-07-30 | Dan Haren | R | 28 | W 7-3 | @ SDN | 22 | 143 | W | 7.0 | 7 | 3 | 3 | 1 | 0 | 6 | 102 | 32 | 70 | 69% | 11-5 | 2.61 | 0.96 |
| 2008-07-31 | Brandon Webb | R | 29 | W 2-1 | @ LAN | 23 | 186 | W | 8.0 | 6 | 1 | 1 | 0 | 1 | 6 | 98 | 29 | 69 | 70% | 15-4 | 3.04 | 1.13 |
| 2008-08-01 | Randy Johnson | L | 45 | W 2-1 | @ LAN | 20 | 576 | W | 6.0 | 5 | 1 | 0 | 0 | 0 | 6 | 75 | 21 | 54 | 72% | 9-7 | 4.35 | 1.31 |
| 2008-08-02 | Yusmeiro Petit | R | 24 | L 2-4 | @ LAN | 3 | 14 | L | 5.0 | 5 | 3 | 3 | 2 | 1 | 1 | 58 | 19 | 39 | 67% | 1-2 | 3.00 | 0.90 |
| 2008-08-03 | Doug Davis | L | 33 | L 3-9 | @ LAN | 16 | 225 | L | 1.2 | 6 | 5 | 5 | 0 | 2 | 1 | 50 | 25 | 25 | 50% | 4-6 | 4.30 | 1.47 |
| 2008-08-04 | Dan Haren | R | 28 | L 13-7 | vs PIT | 23 | 144 | W | 6.0 | 8 | 4 | 4 | 1 | 0 | 8 | 96 | 26 | 70 | 73% | 12-5 | 2.75 | 0.97 |
| 2008-08-05 | Brandon Webb | R | 29 | L 3-1 | vs PIT | 24 | 187 | W | 9.0 | 9 | 1 | 1 | 0 | 0 | 4 | 103 | 36 | 67 | 65% | 16-4 | 2.93 | 1.12 |
| 2008-08-06 | Randy Johnson | L | 45 | W 0-2 | vs PIT | 21 | 577 | L | 7.1 | 7 | 2 | 2 | 1 | 0 | 7 | 109 | 27 | 82 | 75% | 9-8 | 4.25 | 1.30 |
| 2008-08-07 | Yusmeiro Petit | R | 24 | W 4-6 | vs ATL | 4 | 15 | L | 5.0 | 4 | 2 | 2 | 1 | 0 | 6 | 84 | 28 | 56 | 67% | 1-3 | 3.09 | 0.89 |
| 2008-08-08 | Doug Davis | L | 33 | W 6-11 | vs ATL | 17 | 226 | L | 4.1 | 9 | 7 | 7 | 0 | 4 | 2 | 83 | 40 | 43 | 52% | 4-7 | 4.74 | 1.53 |
| 2008-08-09 | Dan Haren | R | 28 | W 4-11 | vs ATL | 24 | 145 | L | 5.1 | 10 | 6 | 6 | 1 | 3 | 5 | 113 | 42 | 71 | 63% | 12-6 | 3.00 | 1.03 |
| 2008-08-10 | Brandon Webb | R | 29 | L 6-1 | vs ATL | 25 | 188 | W | 6.0 | 6 | 1 | 1 | 0 | 2 | 5 | 96 | 34 | 62 | 65% | 17-4 | 2.88 | 1.13 |
| 2008-08-12 | Randy Johnson | L | 45 | W 4-2 | @ COL | 22 | 578 | W | 6.0 | 5 | 2 | 2 | 1 | 1 | 7 | 93 | 25 | 68 | 73% | 10-8 | 4.19 | 1.28 |
| 2008-08-13 | Doug Davis | L | 33 | L 5-6 | @ COL | 18 | 227 | - | 5.0 | 6 | 4 | 3 | 2 | 2 | 4 | 90 | 38 | 52 | 58% | 4-7 | 4.77 | 1.53 |
| 2008-08-14 | Dan Haren | R | 28 | W 6-2 | @ COL | 25 | 146 | W | 8.0 | 7 | 2 | 2 | 1 | 2 | 9 | 127 | 46 | 81 | 64% | 13-6 | 2.96 | 1.03 |
| 2008-08-15 | Brandon Webb | R | 29 | W 12-2 | @ HOU | 26 | 189 | W | 8.0 | 4 | 2 | 2 | 1 | 1 | 6 | 82 | 23 | 59 | 72% | 18-4 | 2.85 | 1.11 |
| 2008-08-16 | Yusmeiro Petit | R | 24 | W 11-5 | @ HOU | 5 | 16 | W | 7.0 | 4 | 2 | 2 | 0 | 1 | 5 | 95 | 28 | 67 | 71% | 2-3 | 3.00 | 0.86 |
| 2008-08-17 | Randy Johnson | L | 45 | L 0-3 | @ HOU | 23 | 579 | L | 7.0 | 8 | 3 | 3 | 1 | 1 | 5 | 106 | 33 | 73 | 69% | 10-9 | 4.17 | 1.28 |
| 2008-08-19 | Doug Davis | L | 33 | L 7-6 | vs SDN | 19 | 228 | W | 6.0 | 7 | 2 | 2 | 0 | 2 | 6 | 99 | 42 | 57 | 58% | 5-7 | 4.67 | 1.53 |
| 2008-08-20 | Dan Haren | R | 28 | L 8-6 | vs SDN | 26 | 147 | W | 6.0 | 11 | 5 | 5 | 1 | 0 | 4 | 81 | 21 | 60 | 74% | 14-6 | 3.12 | 1.06 |
| 2008-08-21 | Brandon Webb | R | 29 | L 4-1 | vs SDN | 27 | 190 | W | 7.0 | 3 | 0 | 0 | 0 | 3 | 8 | 94 | 37 | 57 | 61% | 19-4 | 2.74 | 1.10 |
| 2008-08-22 | Randy Johnson | L | 45 | W 4-5 | vs FLO | 24 | 580 | - | 7.0 | 5 | 3 | 1 | 0 | 3 | 13 | 116 | 40 | 76 | 66% | 10-9 | 4.03 | 1.28 |
| 2008-08-23 | Yusmeiro Petit | R | 24 | L 7-1 | vs FLO | 6 | 17 | W | 6.0 | 2 | 1 | 1 | 1 | 0 | 6 | 75 | 25 | 50 | 67% | 3-3 | 2.81 | 0.79 |
| 2008-08-24 | Doug Davis | L | 33 | W 2-5 | vs FLO | 20 | 229 | L | 7.0 | 7 | 3 | 3 | 1 | 0 | 8 | 110 | 38 | 72 | 65% | 5-8 | 4.62 | 1.50 |
| 2008-08-25 | Dan Haren | R | 28 | L 2-4 | @ SDN | 27 | 148 | - | 7.0 | 9 | 2 | 2 | 0 | 1 | 11 | 99 | 30 | 69 | 70% | 14-6 | 3.10 | 1.07 |
| 2008-08-26 | Brandon Webb | R | 29 | L 2-9 | @ SDN | 28 | 191 | L | 4.2 | 9 | 6 | 6 | 1 | 1 | 4 | 79 | 28 | 51 | 65% | 19-5 | 2.95 | 1.12 |
| 2008-08-27 | Randy Johnson | L | 45 | L 4-5 | @ SDN | 25 | 581 | - | 7.0 | 5 | 3 | 3 | 1 | 1 | 9 | 104 | 37 | 67 | 64% | 10-9 | 4.03 | 1.26 |
| 2008-08-29 | Doug Davis | L | 33 | L 9-3 | vs LAN | 21 | 230 | W | 5.0 | 8 | 2 | 2 | 0 | 3 | 2 | 98 | 43 | 55 | 56% | 6-8 | 4.58 | 1.53 |
| 2008-08-30 | Dan Haren | R | 28 | W 2-6 | vs LAN | 28 | 149 | L | 6.0 | 10 | 5 | 5 | 2 | 0 | 5 | 97 | 28 | 69 | 71% | 14-7 | 3.24 | 1.09 |
| 2008-08-31 | Brandon Webb | R | 29 | W 1-8 | vs LAN | 29 | 192 | L | 3.1 | 8 | 8 | 6 | 2 | 5 | 3 | 89 | 44 | 45 | 51% | 19-6 | 3.19 | 1.17 |
| 2008-09-01 | Randy Johnson | L | 45 | L 8-6 | vs SLN | 26 | 582 | - | 3.2 | 6 | 5 | 5 | 4 | 3 | 8 | 100 | 35 | 65 | 65% | 10-9 | 4.21 | 1.28 |
| 2008-09-02 | Yusmeiro Petit | R | 24 | W 2-8 | vs SLN | 7 | 18 | L | 4.2 | 4 | 5 | 5 | 3 | 3 | 5 | 88 | 36 | 52 | 59% | 3-4 | 3.46 | 0.87 |
| 2008-09-03 | Doug Davis | L | 33 | L 4-3 | vs SLN | 22 | 231 | - | 6.0 | 8 | 3 | 3 | 1 | 1 | 3 | 91 | 35 | 56 | 62% | 6-8 | 4.57 | 1.52 |
| 2008-09-05 | Dan Haren | R | 28 | L 0-7 | @ LAN | 29 | 150 | L | 4.0 | 6 | 5 | 5 | 1 | 4 | 2 | 84 | 39 | 45 | 54% | 14-8 | 3.41 | 1.12 |
| 2008-09-06 | Brandon Webb | R | 29 | L 2-7 | @ LAN | 30 | 193 | L | 5.2 | 5 | 7 | 7 | 1 | 6 | 6 | 98 | 44 | 54 | 55% | 19-7 | 3.41 | 1.19 |
| 2008-09-07 | Max Scherzer | R | 24 | L 3-5 | @ LAN | 4 | 4 | - | 5.0 | 5 | 3 | 3 | 0 | 1 | 11 | 93 | 33 | 60 | 65% | 0-2 | 3.00 | 1.21 |
| 2008-09-08 | Yusmeiro Petit | R | 24 | L 2-6 | @ SFN | 8 | 19 | L | 2.2 | 8 | 5 | 5 | 1 | 3 | 0 | 65 | 26 | 39 | 60% | 3-5 | 4.09 | 1.02 |
| 2008-09-09 | Doug Davis | L | 33 | L 4-5 | @ SFN | 23 | 232 | - | 5.1 | 6 | 2 | 2 | 0 | 2 | 2 | 83 | 35 | 48 | 58% | 6-8 | 4.53 | 1.53 |
| 2008-09-10 | Dan Haren | R | 28 | L 3-4 | @ SFN | 30 | 151 | - | 4.0 | 6 | 2 | 1 | 0 | 3 | 3 | 99 | 36 | 63 | 64% | 14-8 | 3.39 | 1.14 |
| 2008-09-12 | Brandon Webb | R | 29 | L 3-2 | vs CIN | 31 | 194 | W | 8.0 | 5 | 0 | 0 | 0 | 2 | 2 | 96 | 38 | 58 | 60% | 20-7 | 3.28 | 1.18 |
| 2008-09-13 | Randy Johnson | L | 45 | W 2-3 | vs CIN | 27 | 583 | - | 6.0 | 5 | 1 | 1 | 0 | 2 | 3 | 98 | 32 | 66 | 67% | 10-9 | 4.11 | 1.28 |
| 2008-09-14 | Max Scherzer | R | 24 | W 1-2 | vs CIN | 5 | 5 | - | 6.0 | 2 | 1 | 1 | 1 | 3 | 9 | 102 | 34 | 68 | 67% | 0-2 | 2.80 | 1.16 |
| 2008-09-15 | Doug Davis | L | 33 | L 3-1 | vs SFN | 24 | 233 | - | 7.0 | 8 | 1 | 0 | 0 | 0 | 2 | 98 | 28 | 70 | 71% | 6-8 | 4.30 | 1.51 |
| 2008-09-16 | Dan Haren | R | 28 | L 2-0 | vs SFN | 31 | 152 | W | 9.0 | 4 | 0 | 0 | 0 | 2 | 12 | 117 | 34 | 83 | 71% | 15-8 | 3.24 | 1.12 |
| 2008-09-17 | Brandon Webb | R | 29 | L 7-6 | vs SFN | 32 | 195 | W | 7.0 | 8 | 3 | 2 | 0 | 2 | 2 | 88 | 31 | 57 | 65% | 21-7 | 3.25 | 1.19 |
| 2008-09-18 | Randy Johnson | L | 45 | L 3-2 | vs SFN | 28 | 584 | - | 7.0 | 8 | 1 | 1 | 0 | 1 | 4 | 90 | 27 | 63 | 70% | 10-9 | 3.99 | 1.28 |
| 2008-09-19 | Max Scherzer | R | 24 | L 2-3 | @ COL | 6 | 6 | L | 6.0 | 7 | 3 | 3 | 2 | 1 | 8 | 101 | 34 | 67 | 66% | 0-3 | 3.00 | 1.18 |
| 2008-09-20 | Doug Davis | L | 33 | W 5-3 | @ COL | 25 | 234 | - | 6.0 | 6 | 2 | 2 | 1 | 1 | 4 | 87 | 33 | 54 | 62% | 6-8 | 4.25 | 1.49 |
| 2008-09-21 | Dan Haren | R | 28 | W 13-4 | @ COL | 32 | 153 | W | 6.0 | 7 | 3 | 3 | 1 | 0 | 4 | 96 | 31 | 65 | 68% | 16-8 | 3.27 | 1.12 |
| 2008-09-22 | Brandon Webb | R | 29 | W 4-2 | @ SLN | 33 | 196 | W | 7.0 | 8 | 2 | 2 | 0 | 2 | 6 | 133 | 54 | 79 | 59% | 22-7 | 3.23 | 1.20 |
| 2008-09-23 | Randy Johnson | L | 45 | L 4-7 | @ SLN | 29 | 585 | L | 6.0 | 7 | 5 | 5 | 1 | 2 | 1 | 100 | 37 | 63 | 63% | 10-10 | 4.11 | 1.29 |
| 2008-09-24 | Max Scherzer | R | 24 | L 2-4 | @ SLN | 7 | 7 | L | 5.0 | 7 | 4 | 2 | 0 | 2 | 4 | 89 | 37 | 52 | 58% | 0-4 | 3.05 | 1.23 |
| 2008-09-25 | Doug Davis | L | 33 | L 3-12 | @ SLN | 26 | 235 | - | 4.0 | 7 | 3 | 3 | 0 | 5 | 3 | 85 | 40 | 45 | 53% | 6-8 | 4.32 | 1.53 |
| 2008-09-26 | Dan Haren | R | 28 | L 6-4 | vs COL | 33 | 154 | - | 7.0 | 8 | 4 | 4 | 0 | 1 | 9 | 109 | 37 | 72 | 66% | 16-8 | 3.33 | 1.13 |
| 2008-09-27 | Brandon Webb | R | 29 | L 6-4 | vs COL | 34 | 197 | - | 7.0 | 6 | 4 | 4 | 0 | 2 | 7 | 107 | 40 | 67 | 63% | 22-7 | 3.29 | 1.19 |
| 2008-09-28 | Randy Johnson | L | 45 | L 2-1 | vs COL | 30 | 586 | W | 9.0 | 2 | 1 | 0 | 0 | 1 | 9 | 103 | 30 | 73 | 71% | 11-10 | 3.91 | 1.24 |