| East | W | L | Pct | GB |
| Boston | 96 | 66 | .593 | -- |
| NY Yankees | 94 | 68 | .580 | 2.0 |
| Toronto | 83 | 79 | .512 | 13.0 |
| Baltimore | 69 | 93 | .426 | 27.0 |
| Tampa Bay | 66 | 96 | .407 | 30.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2007-04-02 | Scott Kazmir | L | 23 | L 5-9 | @ NYA | 1 | 64 | - | 5.0 | 6 | 5 | 5 | 1 | 4 | 5 | 106 | 44 | 62 | 58% | 0-0 | 9.00 | 2.00 |
| 2007-04-05 | Jae-Wong Seo | R | 30 | W 7-6 | @ NYA | 1 | 93 | - | 6.1 | 11 | 5 | 5 | 0 | 1 | 2 | 99 | 39 | 60 | 61% | 0-0 | 7.50 | 2.00 |
| 2007-04-06 | James Shields | R | 25 | L 6-5 | vs TOR | 1 | 22 | - | 6.2 | 6 | 3 | 3 | 0 | 2 | 3 | 103 | 36 | 67 | 65% | 0-0 | 3.86 | 1.14 |
| 2007-04-07 | Casey Fossum | L | 29 | W 5-8 | vs TOR | 1 | 111 | L | 3.2 | 8 | 7 | 7 | 1 | 1 | 3 | 76 | 30 | 46 | 61% | 0-1 | 15.75 | 2.25 |
| 2007-04-08 | Scott Kazmir | L | 23 | W 3-6 | vs TOR | 2 | 65 | L | 7.0 | 6 | 4 | 4 | 2 | 2 | 10 | 110 | 31 | 79 | 72% | 0-1 | 6.75 | 1.50 |
| 2007-04-09 | Edwin Jackson | R | 24 | L 4-8 | @ TEX | 1 | 16 | L | 5.2 | 8 | 4 | 4 | 0 | 1 | 4 | 113 | 47 | 66 | 58% | 0-1 | 6.00 | 1.50 |
| 2007-04-10 | Jae-Wong Seo | R | 30 | L 9-12 | @ TEX | 2 | 94 | L | 3.0 | 8 | 10 | 5 | 3 | 3 | 3 | 90 | 40 | 50 | 56% | 0-1 | 10.00 | 2.56 |
| 2007-04-11 | James Shields | R | 25 | W 6-5 | @ TEX | 2 | 23 | W | 7.0 | 5 | 5 | 4 | 3 | 1 | 8 | 99 | 34 | 65 | 66% | 1-0 | 4.50 | 1.00 |
| 2007-04-12 | Casey Fossum | L | 29 | L 2-3 | @ MIN | 2 | 112 | - | 7.0 | 6 | 2 | 2 | 1 | 0 | 2 | 91 | 34 | 57 | 63% | 0-1 | 7.36 | 1.36 |
| 2007-04-13 | Scott Kazmir | L | 23 | W 4-2 | @ MIN | 3 | 66 | W | 8.0 | 6 | 2 | 2 | 1 | 0 | 6 | 115 | 38 | 77 | 67% | 1-1 | 4.95 | 1.20 |
| 2007-04-14 | Edwin Jackson | R | 24 | L 5-12 | @ MIN | 2 | 17 | L | 3.0 | 3 | 5 | 4 | 0 | 5 | 0 | 69 | 34 | 35 | 51% | 0-2 | 8.00 | 1.89 |
| 2007-04-15 | Jae-Wong Seo | R | 30 | W 6-4 | @ MIN | 3 | 95 | - | 7.0 | 9 | 4 | 4 | 0 | 0 | 4 | 92 | 28 | 64 | 70% | 0-1 | 7.88 | 2.00 |
| 2007-04-16 | James Shields | R | 25 | W 7-9 | vs BAL | 3 | 24 | - | 6.1 | 9 | 5 | 5 | 2 | 2 | 5 | 107 | 38 | 69 | 64% | 1-0 | 5.40 | 1.25 |
| 2007-04-17 | Casey Fossum | L | 29 | L 6-4 | vs BAL | 3 | 113 | W | 7.0 | 5 | 3 | 3 | 0 | 1 | 4 | 88 | 29 | 59 | 67% | 1-1 | 6.00 | 1.17 |
| 2007-04-18 | Scott Kazmir | L | 23 | W 4-6 | vs BAL | 4 | 67 | - | 4.0 | 6 | 3 | 3 | 0 | 4 | 3 | 100 | 41 | 59 | 59% | 1-1 | 5.25 | 1.42 |
| 2007-04-20 | Edwin Jackson | R | 24 | W 3-4 | vs CLE | 3 | 18 | - | 6.0 | 5 | 3 | 3 | 1 | 5 | 5 | 108 | 47 | 61 | 56% | 0-2 | 6.60 | 1.80 |
| 2007-04-21 | Jae-Wong Seo | R | 30 | L 6-5 | vs CLE | 4 | 96 | W | 6.0 | 8 | 5 | 5 | 1 | 2 | 2 | 97 | 36 | 61 | 63% | 1-1 | 7.77 | 1.91 |
| 2007-04-22 | James Shields | R | 25 | W 4-6 | vs CLE | 4 | 25 | - | 8.0 | 2 | 2 | 2 | 1 | 1 | 12 | 102 | 37 | 65 | 64% | 1-0 | 4.50 | 1.00 |
| 2007-04-23 | Casey Fossum | L | 29 | L 10-8 | vs NYA | 4 | 114 | W | 5.2 | 10 | 6 | 6 | 2 | 1 | 2 | 82 | 31 | 51 | 62% | 2-1 | 7.04 | 1.39 |
| 2007-04-24 | Scott Kazmir | L | 23 | L 6-4 | vs NYA | 5 | 68 | - | 6.2 | 5 | 3 | 1 | 1 | 2 | 5 | 107 | 49 | 58 | 54% | 1-1 | 4.35 | 1.32 |
| 2007-04-25 | Edwin Jackson | R | 24 | L 1-9 | @ ANA | 4 | 19 | L | 6.0 | 8 | 6 | 3 | 0 | 1 | 4 | 99 | 35 | 64 | 65% | 0-3 | 6.00 | 1.71 |
| 2007-04-26 | Jae-Wong Seo | R | 30 | L 3-11 | @ ANA | 5 | 97 | L | 1.1 | 7 | 6 | 6 | 1 | 2 | 1 | 54 | 24 | 30 | 56% | 1-2 | 9.38 | 2.13 |
| 2007-04-27 | James Shields | R | 25 | W 4-1 | @ OAK | 5 | 26 | W | 8.0 | 4 | 1 | 1 | 1 | 1 | 9 | 111 | 36 | 75 | 68% | 2-0 | 3.75 | 0.92 |
| 2007-04-28 | Casey Fossum | L | 29 | L 5-12 | @ OAK | 5 | 115 | L | 5.0 | 9 | 9 | 9 | 2 | 3 | 5 | 96 | 37 | 59 | 61% | 2-2 | 8.68 | 1.57 |
| 2007-04-29 | Scott Kazmir | L | 23 | W 5-3 | @ OAK | 6 | 69 | W | 7.0 | 6 | 2 | 2 | 2 | 2 | 1 | 105 | 42 | 63 | 60% | 2-1 | 4.03 | 1.29 |
| 2007-05-01 | Edwin Jackson | R | 24 | W 1-9 | vs MIN | 5 | 20 | L | 1.1 | 5 | 6 | 4 | 0 | 2 | 1 | 49 | 20 | 29 | 59% | 0-4 | 7.36 | 1.95 |
| 2007-05-02 | Jae-Wong Seo | R | 30 | L 4-3 | vs MIN | 6 | 98 | - | 6.0 | 7 | 2 | 2 | 1 | 1 | 3 | 91 | 33 | 58 | 64% | 1-2 | 8.10 | 1.97 |
| 2007-05-03 | James Shields | R | 25 | L 6-4 | vs MIN | 6 | 27 | W | 7.1 | 9 | 3 | 3 | 0 | 2 | 8 | 107 | 40 | 67 | 63% | 3-0 | 3.77 | 1.02 |
| 2007-05-04 | Casey Fossum | L | 29 | W 2-5 | vs OAK | 6 | 116 | - | 6.0 | 5 | 1 | 1 | 0 | 3 | 4 | 98 | 39 | 59 | 60% | 2-2 | 7.41 | 1.53 |
| 2007-05-05 | Scott Kazmir | L | 23 | L 3-2 | vs OAK | 7 | 70 | - | 6.0 | 5 | 1 | 1 | 0 | 3 | 8 | 105 | 40 | 65 | 62% | 2-1 | 3.68 | 1.30 |
| 2007-05-06 | Edwin Jackson | R | 24 | W 3-5 | vs OAK | 6 | 21 | L | 6.1 | 6 | 4 | 4 | 1 | 4 | 6 | 114 | 46 | 68 | 60% | 0-5 | 7.07 | 1.89 |
| 2007-05-08 | Jae-Wong Seo | R | 30 | L 3-8 | @ BAL | 7 | 99 | L | 3.0 | 6 | 5 | 5 | 1 | 1 | 1 | 64 | 22 | 42 | 66% | 1-3 | 8.73 | 2.00 |
| 2007-05-09 | James Shields | R | 25 | L 0-1 | @ BAL | 7 | 28 | - | 9.0 | 3 | 0 | 0 | 0 | 1 | 4 | 107 | 42 | 65 | 61% | 3-0 | 3.12 | 0.92 |
| 2007-05-10 | Casey Fossum | L | 29 | L 6-11 | @ BAL | 7 | 117 | L | 5.2 | 9 | 8 | 5 | 1 | 3 | 2 | 95 | 36 | 59 | 62% | 2-3 | 7.43 | 1.60 |
| 2007-05-11 | Scott Kazmir | L | 23 | L 1-5 | @ TOR | 8 | 71 | L | 6.1 | 9 | 5 | 4 | 1 | 3 | 6 | 122 | 47 | 75 | 61% | 2-2 | 3.96 | 1.38 |
| 2007-05-12 | Edwin Jackson | R | 24 | L 4-5 | @ TOR | 7 | 22 | - | 6.0 | 6 | 4 | 4 | 2 | 2 | 9 | 104 | 42 | 62 | 60% | 0-5 | 6.88 | 1.79 |
| 2007-05-13 | Jae-Wong Seo | R | 30 | W 2-1 | @ TOR | 8 | 100 | W | 7.0 | 2 | 0 | 0 | 0 | 2 | 7 | 101 | 41 | 60 | 59% | 2-3 | 7.20 | 1.75 |
| 2007-05-15 | James Shields | R | 25 | L 4-3 | vs TEX | 8 | 29 | - | 8.0 | 6 | 3 | 3 | 1 | 0 | 5 | 98 | 35 | 63 | 64% | 3-0 | 3.15 | 0.90 |
| 2007-05-16 | Casey Fossum | L | 29 | L 11-8 | vs TEX | 8 | 118 | W | 5.0 | 9 | 6 | 6 | 3 | 0 | 4 | 83 | 31 | 52 | 63% | 3-3 | 7.80 | 1.62 |
| 2007-05-17 | Scott Kazmir | L | 23 | L 8-6 | vs TEX | 9 | 72 | - | 4.0 | 3 | 3 | 1 | 0 | 6 | 9 | 107 | 46 | 61 | 57% | 2-2 | 3.83 | 1.44 |
| 2007-05-18 | Edwin Jackson | R | 24 | W 4-8 | vs FLO | 8 | 23 | L | 2.2 | 7 | 7 | 6 | 1 | 3 | 2 | 61 | 28 | 33 | 54% | 0-6 | 7.78 | 1.92 |
| 2007-05-19 | Jae-Wong Seo | R | 30 | W 2-7 | vs FLO | 9 | 101 | L | 5.1 | 8 | 7 | 7 | 3 | 3 | 2 | 86 | 33 | 53 | 62% | 2-4 | 7.80 | 1.80 |
| 2007-05-20 | James Shields | R | 25 | W 3-4 | vs FLO | 9 | 30 | - | 7.0 | 5 | 1 | 1 | 0 | 3 | 8 | 101 | 35 | 66 | 65% | 3-0 | 2.96 | 0.93 |
| 2007-05-22 | Scott Kazmir | L | 23 | W 2-5 | vs SEA | 10 | 73 | - | 5.0 | 4 | 2 | 2 | 0 | 3 | 4 | 96 | 37 | 59 | 61% | 2-2 | 3.81 | 1.44 |
| 2007-05-23 | Casey Fossum | L | 29 | W 1-5 | vs SEA | 9 | 119 | L | 5.1 | 5 | 3 | 1 | 0 | 4 | 3 | 103 | 49 | 54 | 52% | 3-4 | 7.20 | 1.64 |
| 2007-05-24 | Jae-Wong Seo | R | 30 | L 13-12 | vs SEA | 10 | 102 | W | 5.0 | 13 | 7 | 6 | 0 | 1 | 1 | 82 | 31 | 51 | 62% | 3-4 | 8.10 | 1.90 |
| 2007-05-25 | James Shields | R | 25 | L 4-5 | @ CHA | 10 | 31 | - | 7.0 | 10 | 4 | 4 | 1 | 3 | 2 | 115 | 45 | 70 | 61% | 3-0 | 3.16 | 1.01 |
| 2007-05-27 | Scott Kazmir | L | 23 | W 11-5 | @ CHA | 11 | 74 | W | 7.0 | 8 | 4 | 4 | 0 | 3 | 7 | 107 | 40 | 67 | 63% | 3-2 | 3.95 | 1.45 |
| 2007-05-28 | Edwin Jackson | R | 24 | L 6-5 | vs DET | 9 | 24 | - | 6.0 | 8 | 3 | 2 | 1 | 2 | 9 | 113 | 42 | 71 | 63% | 0-6 | 7.12 | 1.88 |
| 2007-05-29 | Casey Fossum | L | 29 | W 2-14 | vs DET | 10 | 120 | L | 1.0 | 7 | 5 | 5 | 1 | 0 | 1 | 31 | 11 | 20 | 65% | 3-5 | 7.94 | 1.75 |
| 2007-05-30 | James Shields | R | 25 | L 5-3 | vs DET | 11 | 32 | W | 9.0 | 7 | 3 | 3 | 0 | 1 | 5 | 104 | 35 | 69 | 66% | 4-0 | 3.14 | 1.00 |
| 2007-06-01 | Scott Kazmir | L | 23 | W 1-4 | vs KCA | 12 | 75 | L | 7.0 | 8 | 3 | 3 | 0 | 1 | 7 | 103 | 34 | 69 | 67% | 3-3 | 3.95 | 1.44 |
| 2007-06-02 | Edwin Jackson | R | 24 | W 4-9 | vs KCA | 10 | 25 | L | 3.1 | 6 | 6 | 6 | 0 | 4 | 4 | 91 | 36 | 55 | 60% | 0-7 | 7.83 | 1.98 |
| 2007-06-03 | J.P. Howell | L | 24 | L 5-1 | vs KCA | 1 | 24 | W | 8.0 | 5 | 1 | 1 | 1 | 0 | 7 | 98 | 37 | 61 | 62% | 1-0 | 1.13 | 0.63 |
| 2007-06-04 | James Shields | R | 25 | L 4-2 | vs KCA | 12 | 33 | W | 7.1 | 4 | 2 | 2 | 2 | 1 | 5 | 101 | 31 | 70 | 69% | 5-0 | 3.07 | 0.97 |
| 2007-06-05 | Andy Sonnanstine | R | 24 | L 11-12 | @ TOR | 1 | 1 | - | 7.0 | 8 | 6 | 6 | 1 | 0 | 5 | 92 | 24 | 68 | 74% | 0-0 | 7.71 | 1.14 |
| 2007-06-06 | Scott Kazmir | L | 23 | W 6-2 | @ TOR | 13 | 76 | W | 5.0 | 6 | 2 | 2 | 0 | 5 | 4 | 103 | 38 | 65 | 63% | 4-3 | 3.92 | 1.49 |
| 2007-06-07 | Edwin Jackson | R | 24 | W 5-3 | @ TOR | 11 | 26 | - | 6.0 | 4 | 3 | 3 | 1 | 2 | 6 | 100 | 40 | 60 | 60% | 0-7 | 7.44 | 1.87 |
| 2007-06-08 | J.P. Howell | L | 24 | L 8-14 | @ FLO | 2 | 25 | - | 5.0 | 8 | 6 | 6 | 1 | 3 | 9 | 103 | 42 | 61 | 59% | 1-0 | 4.85 | 1.23 |
| 2007-06-09 | James Shields | R | 25 | W 7-2 | @ FLO | 13 | 34 | W | 7.0 | 6 | 2 | 2 | 1 | 0 | 9 | 113 | 38 | 75 | 66% | 6-0 | 3.03 | 0.96 |
| 2007-06-10 | Andy Sonnanstine | R | 24 | W 9-4 | @ FLO | 2 | 2 | W | 7.0 | 7 | 2 | 2 | 2 | 0 | 10 | 98 | 28 | 70 | 71% | 1-0 | 5.14 | 1.07 |
| 2007-06-12 | Scott Kazmir | L | 23 | L 11-4 | vs SDN | 14 | 77 | - | 6.0 | 9 | 4 | 4 | 0 | 2 | 11 | 116 | 37 | 79 | 68% | 4-3 | 4.07 | 1.51 |
| 2007-06-13 | Edwin Jackson | R | 24 | W 0-9 | vs SDN | 12 | 27 | L | 0.1 | 5 | 5 | 5 | 2 | 2 | 1 | 42 | 19 | 23 | 55% | 0-8 | 8.15 | 1.96 |
| 2007-06-14 | J.P. Howell | L | 24 | W 1-7 | vs SDN | 3 | 26 | L | 7.0 | 4 | 2 | 1 | 0 | 3 | 2 | 94 | 39 | 55 | 59% | 1-1 | 3.60 | 1.15 |
| 2007-06-15 | James Shields | R | 25 | L 2-12 | @ COL | 14 | 35 | L | 6.0 | 6 | 5 | 5 | 2 | 1 | 2 | 85 | 34 | 51 | 60% | 6-1 | 3.29 | 0.97 |
| 2007-06-16 | Andy Sonnanstine | R | 24 | L 5-10 | @ COL | 3 | 3 | L | 5.0 | 6 | 7 | 7 | 3 | 2 | 5 | 98 | 38 | 60 | 61% | 1-1 | 7.11 | 1.21 |
| 2007-06-17 | Scott Kazmir | L | 23 | W 7-4 | @ COL | 15 | 78 | W | 6.0 | 6 | 3 | 3 | 2 | 4 | 5 | 119 | 54 | 65 | 55% | 5-3 | 4.10 | 1.52 |
| 2007-06-18 | Edwin Jackson | R | 24 | W 10-2 | @ ARI | 13 | 28 | - | 4.2 | 4 | 2 | 2 | 0 | 4 | 1 | 96 | 44 | 52 | 54% | 0-8 | 7.89 | 1.96 |
| 2007-06-19 | J.P. Howell | L | 24 | L 8-10 | @ ARI | 4 | 27 | - | 5.1 | 9 | 4 | 4 | 1 | 4 | 4 | 107 | 42 | 65 | 61% | 1-1 | 4.32 | 1.44 |
| 2007-06-20 | James Shields | R | 25 | L 4-7 | @ ARI | 15 | 36 | L | 5.0 | 10 | 6 | 6 | 2 | 0 | 4 | 80 | 26 | 54 | 68% | 6-2 | 3.63 | 1.02 |
| 2007-06-22 | Andy Sonnanstine | R | 24 | W 3-6 | vs LAN | 4 | 4 | L | 7.0 | 10 | 4 | 4 | 1 | 1 | 1 | 97 | 34 | 63 | 65% | 1-2 | 6.58 | 1.31 |
| 2007-06-23 | Scott Kazmir | L | 23 | L 4-3 | vs LAN | 16 | 79 | - | 6.0 | 7 | 3 | 3 | 0 | 5 | 5 | 116 | 48 | 68 | 59% | 5-3 | 4.13 | 1.55 |
| 2007-06-24 | Edwin Jackson | R | 24 | L 9-4 | vs LAN | 14 | 29 | W | 6.0 | 9 | 2 | 2 | 1 | 1 | 2 | 89 | 40 | 49 | 55% | 1-8 | 7.43 | 1.94 |
| 2007-06-25 | J.P. Howell | L | 24 | W 4-5 | vs CHA | 5 | 28 | - | 5.0 | 8 | 3 | 3 | 0 | 3 | 7 | 110 | 44 | 66 | 60% | 1-1 | 4.50 | 1.57 |
| 2007-06-26 | James Shields | R | 26 | W 1-6 | vs CHA | 16 | 37 | L | 7.0 | 9 | 5 | 5 | 2 | 0 | 11 | 110 | 35 | 75 | 68% | 6-3 | 3.80 | 1.03 |
| 2007-06-27 | Andy Sonnanstine | R | 24 | W 3-5 | vs CHA | 5 | 5 | - | 6.1 | 6 | 2 | 2 | 0 | 0 | 6 | 103 | 33 | 70 | 68% | 1-2 | 5.91 | 1.25 |
| 2007-06-28 | Scott Kazmir | L | 23 | W 1-5 | vs CHA | 17 | 80 | L | 5.1 | 6 | 4 | 4 | 2 | 3 | 9 | 111 | 41 | 70 | 63% | 5-4 | 4.28 | 1.56 |
| 2007-06-29 | Edwin Jackson | R | 24 | L 1-2 | @ CLE | 15 | 30 | - | 6.0 | 6 | 1 | 1 | 0 | 2 | 6 | 102 | 37 | 65 | 64% | 1-8 | 6.91 | 1.88 |
| 2007-06-30 | J.P. Howell | L | 24 | L 6-8 | @ CLE | 6 | 29 | L | 4.1 | 8 | 5 | 5 | 1 | 1 | 5 | 97 | 40 | 57 | 59% | 1-2 | 5.14 | 1.60 |
| 2007-07-01 | James Shields | R | 26 | L 2-3 | @ CLE | 17 | 38 | L | 6.1 | 6 | 3 | 2 | 1 | 0 | 10 | 116 | 39 | 77 | 66% | 6-4 | 3.76 | 1.03 |
| 2007-07-02 | Andy Sonnanstine | R | 24 | L 2-10 | @ CLE | 6 | 6 | L | 6.0 | 7 | 3 | 3 | 1 | 2 | 3 | 99 | 41 | 58 | 59% | 1-3 | 5.68 | 1.29 |
| 2007-07-03 | Scott Kazmir | L | 23 | L 1-4 | @ BOS | 18 | 81 | L | 6.0 | 6 | 4 | 3 | 0 | 3 | 6 | 113 | 38 | 75 | 66% | 5-5 | 4.29 | 1.56 |
| 2007-07-04 | Edwin Jackson | R | 24 | L 5-7 | @ BOS | 16 | 31 | L | 5.0 | 9 | 7 | 7 | 1 | 1 | 5 | 102 | 38 | 64 | 63% | 1-9 | 7.30 | 1.89 |
| 2007-07-05 | J.P. Howell | L | 24 | L 4-15 | @ BOS | 7 | 30 | L | 0.2 | 6 | 6 | 6 | 1 | 2 | 1 | 43 | 21 | 22 | 51% | 1-3 | 6.69 | 1.83 |
| 2007-07-06 | James Shields | R | 26 | W 6-5 | @ KCA | 18 | 39 | W | 7.2 | 7 | 4 | 4 | 0 | 0 | 6 | 112 | 36 | 76 | 68% | 7-4 | 3.81 | 1.02 |
| 2007-07-07 | Andy Sonnanstine | R | 24 | L 7-8 | @ KCA | 7 | 7 | - | 7.0 | 6 | 4 | 3 | 1 | 1 | 5 | 102 | 33 | 69 | 68% | 1-3 | 5.40 | 1.24 |
| 2007-07-08 | Scott Kazmir | L | 23 | L 4-12 | @ KCA | 19 | 82 | L | 5.0 | 7 | 5 | 4 | 0 | 3 | 4 | 111 | 48 | 63 | 57% | 5-6 | 4.42 | 1.58 |
| 2007-07-12 | James Shields | R | 26 | W 3-7 | vs NYA | 19 | 40 | L | 6.0 | 9 | 6 | 5 | 3 | 1 | 2 | 92 | 32 | 60 | 65% | 7-5 | 3.97 | 1.05 |
| 2007-07-13 | Scott Kazmir | L | 23 | L 6-4 | vs NYA | 20 | 83 | W | 6.0 | 4 | 1 | 0 | 0 | 4 | 7 | 116 | 46 | 70 | 60% | 6-6 | 4.19 | 1.57 |
| 2007-07-14 | Andy Sonnanstine | R | 24 | W 4-6 | vs NYA | 8 | 8 | L | 6.1 | 9 | 5 | 5 | 2 | 1 | 3 | 104 | 40 | 64 | 62% | 1-4 | 5.54 | 1.27 |
| 2007-07-15 | Edwin Jackson | R | 24 | W 6-7 | vs NYA | 17 | 32 | - | 6.0 | 6 | 4 | 4 | 1 | 2 | 6 | 110 | 43 | 67 | 61% | 1-9 | 7.11 | 1.84 |
| 2007-07-17 | James Shields | R | 26 | L 8-3 | vs ANA | 20 | 41 | W | 7.0 | 7 | 2 | 2 | 0 | 1 | 2 | 107 | 37 | 70 | 65% | 8-5 | 3.90 | 1.06 |
| 2007-07-18 | Scott Kazmir | L | 23 | L 7-2 | vs ANA | 21 | 84 | W | 7.0 | 3 | 1 | 1 | 0 | 1 | 6 | 94 | 29 | 65 | 69% | 7-6 | 4.03 | 1.51 |
| 2007-07-19 | Andy Sonnanstine | R | 24 | W 0-3 | vs ANA | 9 | 9 | L | 7.0 | 8 | 3 | 3 | 0 | 0 | 6 | 103 | 25 | 78 | 76% | 1-5 | 5.34 | 1.25 |
| 2007-07-20 | Edwin Jackson | R | 24 | W 14-4 | @ NYA | 18 | 33 | W | 6.0 | 4 | 0 | 0 | 0 | 4 | 4 | 101 | 43 | 58 | 57% | 2-9 | 6.62 | 1.80 |
| 2007-07-21 | Jason Hammel | R | 25 | L 3-7 | @ NYA | 1 | 10 | - | 4.0 | 3 | 2 | 2 | 1 | 3 | 1 | 70 | 31 | 39 | 56% | 1-0 | 5.73 | 1.82 |
| 2007-07-21 | J.P. Howell | L | 24 | L 5-17 | @ NYA | 8 | 31 | L | 5.0 | 10 | 7 | 7 | 0 | 1 | 2 | 104 | 44 | 60 | 58% | 1-4 | 7.43 | 1.88 |
| 2007-07-22 | James Shields | R | 26 | L 4-21 | @ NYA | 21 | 42 | L | 3.1 | 10 | 10 | 10 | 1 | 4 | 1 | 79 | 31 | 48 | 61% | 8-6 | 4.44 | 1.13 |
| 2007-07-24 | Scott Kazmir | L | 23 | L 0-3 | @ BAL | 22 | 85 | L | 6.2 | 7 | 3 | 3 | 0 | 3 | 8 | 115 | 43 | 72 | 63% | 7-7 | 4.02 | 1.51 |
| 2007-07-25 | Andy Sonnanstine | R | 24 | L 1-6 | @ BAL | 10 | 10 | L | 6.0 | 7 | 5 | 5 | 0 | 3 | 4 | 105 | 38 | 67 | 64% | 1-6 | 5.54 | 1.29 |
| 2007-07-26 | Edwin Jackson | R | 24 | L 7-10 | @ BAL | 19 | 34 | L | 3.1 | 7 | 6 | 6 | 0 | 3 | 2 | 85 | 39 | 46 | 54% | 2-10 | 7.00 | 1.86 |
| 2007-07-27 | Jason Hammel | R | 25 | W 1-7 | vs BOS | 2 | 11 | L | 5.1 | 1 | 2 | 2 | 0 | 2 | 4 | 88 | 32 | 56 | 64% | 1-1 | 5.33 | 1.59 |
| 2007-07-28 | James Shields | R | 26 | W 6-12 | vs BOS | 22 | 43 | - | 5.0 | 6 | 3 | 3 | 0 | 1 | 7 | 93 | 33 | 60 | 65% | 8-6 | 4.47 | 1.14 |
| 2007-07-29 | Scott Kazmir | L | 24 | L 5-2 | vs BOS | 23 | 86 | - | 6.0 | 6 | 0 | 0 | 0 | 1 | 8 | 95 | 32 | 63 | 66% | 7-7 | 3.85 | 1.49 |
| 2007-07-30 | Andy Sonnanstine | R | 24 | L 5-4 | vs TOR | 11 | 11 | - | 6.2 | 6 | 4 | 4 | 0 | 3 | 3 | 93 | 33 | 60 | 65% | 1-6 | 5.58 | 1.31 |
| 2007-07-31 | Edwin Jackson | R | 24 | W 0-2 | vs TOR | 20 | 35 | L | 6.0 | 5 | 1 | 0 | 0 | 1 | 5 | 102 | 37 | 65 | 64% | 2-11 | 6.56 | 1.80 |
| 2007-08-01 | Jason Hammel | R | 25 | L 6-2 | vs TOR | 3 | 12 | - | 3.0 | 3 | 2 | 2 | 0 | 1 | 1 | 51 | 21 | 30 | 59% | 1-1 | 5.40 | 1.57 |
| 2007-08-03 | James Shields | R | 26 | W 1-3 | vs BAL | 23 | 44 | L | 6.2 | 6 | 3 | 3 | 1 | 3 | 6 | 105 | 40 | 65 | 62% | 8-7 | 4.44 | 1.15 |
| 2007-08-04 | Scott Kazmir | L | 24 | L 9-2 | vs BAL | 24 | 87 | W | 7.0 | 7 | 1 | 1 | 0 | 2 | 9 | 107 | 36 | 71 | 66% | 8-7 | 3.72 | 1.48 |
| 2007-08-05 | Andy Sonnanstine | R | 24 | W 3-11 | vs BAL | 12 | 12 | L | 3.2 | 8 | 7 | 7 | 1 | 2 | 1 | 74 | 24 | 50 | 68% | 1-7 | 6.12 | 1.37 |
| 2007-08-06 | Edwin Jackson | R | 24 | L 4-6 | @ DET | 21 | 36 | - | 6.0 | 7 | 2 | 2 | 0 | 4 | 2 | 111 | 46 | 65 | 59% | 2-11 | 6.35 | 1.80 |
| 2007-08-07 | Jason Hammel | R | 25 | L 6-9 | @ DET | 4 | 13 | - | 4.0 | 10 | 5 | 5 | 0 | 1 | 3 | 78 | 34 | 44 | 56% | 1-1 | 6.09 | 1.71 |
| 2007-08-08 | James Shields | R | 26 | W 7-1 | @ DET | 24 | 45 | W | 7.0 | 5 | 1 | 1 | 1 | 0 | 9 | 104 | 36 | 68 | 65% | 9-7 | 4.31 | 1.13 |
| 2007-08-09 | Scott Kazmir | L | 24 | W 8-1 | @ DET | 25 | 88 | W | 6.0 | 3 | 0 | 0 | 0 | 1 | 7 | 94 | 36 | 58 | 62% | 9-7 | 3.58 | 1.45 |
| 2007-08-10 | Andy Sonnanstine | R | 24 | L 4-7 | @ TEX | 13 | 13 | L | 4.1 | 7 | 5 | 5 | 1 | 1 | 3 | 78 | 27 | 51 | 65% | 1-8 | 6.38 | 1.41 |
| 2007-08-11 | Edwin Jackson | R | 24 | W 3-0 | @ TEX | 22 | 37 | W | 9.0 | 4 | 0 | 0 | 0 | 1 | 8 | 110 | 37 | 73 | 66% | 3-11 | 5.84 | 1.70 |
| 2007-08-12 | Jason Hammel | R | 25 | L 1-9 | @ TEX | 5 | 14 | L | 4.0 | 7 | 5 | 5 | 1 | 4 | 1 | 94 | 41 | 53 | 56% | 1-2 | 6.63 | 1.82 |
| 2007-08-13 | James Shields | R | 26 | L 0-3 | @ BOS | 25 | 46 | L | 6.0 | 5 | 1 | 1 | 0 | 0 | 5 | 104 | 40 | 64 | 62% | 9-8 | 4.21 | 1.12 |
| 2007-08-14 | Scott Kazmir | L | 24 | L 1-2 | @ BOS | 26 | 89 | - | 6.0 | 4 | 0 | 0 | 0 | 3 | 8 | 94 | 40 | 54 | 57% | 9-7 | 3.44 | 1.44 |
| 2007-08-15 | Andy Sonnanstine | R | 24 | W 6-5 | @ BOS | 14 | 14 | W | 6.2 | 4 | 3 | 3 | 1 | 2 | 3 | 107 | 43 | 64 | 60% | 2-8 | 6.17 | 1.36 |
| 2007-08-17 | Edwin Jackson | R | 24 | W 1-2 | vs CLE | 23 | 38 | L | 6.0 | 7 | 2 | 2 | 0 | 5 | 4 | 100 | 40 | 60 | 60% | 3-12 | 5.69 | 1.72 |
| 2007-08-18 | Jason Hammel | R | 25 | W 1-8 | vs CLE | 6 | 15 | L | 5.0 | 8 | 4 | 4 | 2 | 0 | 4 | 105 | 36 | 69 | 66% | 1-3 | 6.70 | 1.79 |
| 2007-08-19 | James Shields | R | 26 | L 4-3 | vs CLE | 26 | 47 | - | 6.0 | 6 | 2 | 2 | 0 | 1 | 6 | 103 | 32 | 71 | 69% | 9-8 | 4.17 | 1.12 |
| 2007-08-20 | Scott Kazmir | L | 24 | W 0-6 | vs BOS | 27 | 90 | L | 5.2 | 7 | 6 | 6 | 1 | 4 | 8 | 107 | 44 | 63 | 59% | 9-8 | 3.64 | 1.45 |
| 2007-08-21 | Andy Sonnanstine | R | 24 | W 6-8 | vs BOS | 15 | 15 | L | 5.0 | 8 | 7 | 7 | 0 | 0 | 5 | 99 | 32 | 67 | 68% | 2-9 | 6.53 | 1.37 |
| 2007-08-22 | Edwin Jackson | R | 24 | L 2-1 | vs BOS | 24 | 39 | W | 6.0 | 5 | 1 | 1 | 0 | 5 | 3 | 103 | 47 | 56 | 54% | 4-12 | 5.49 | 1.72 |
| 2007-08-23 | Jason Hammel | R | 25 | W 2-12 | vs OAK | 7 | 16 | L | 3.0 | 5 | 6 | 6 | 1 | 5 | 2 | 78 | 34 | 44 | 56% | 1-4 | 7.43 | 1.89 |
| 2007-08-24 | James Shields | R | 26 | L 12-2 | vs OAK | 27 | 48 | W | 8.1 | 9 | 2 | 2 | 1 | 1 | 8 | 112 | 33 | 79 | 71% | 10-8 | 4.09 | 1.12 |
| 2007-08-25 | Scott Kazmir | L | 24 | L 14-3 | vs OAK | 28 | 91 | W | 8.0 | 5 | 3 | 3 | 1 | 0 | 13 | 105 | 30 | 75 | 71% | 10-8 | 3.63 | 1.42 |
| 2007-08-26 | Andy Sonnanstine | R | 24 | L 7-4 | vs OAK | 16 | 16 | W | 5.0 | 5 | 2 | 2 | 0 | 2 | 7 | 95 | 39 | 56 | 59% | 3-9 | 6.38 | 1.38 |
| 2007-08-27 | Edwin Jackson | R | 24 | L 4-5 | @ CHA | 25 | 40 | - | 6.0 | 9 | 4 | 4 | 3 | 1 | 2 | 104 | 37 | 67 | 64% | 4-12 | 5.51 | 1.71 |
| 2007-08-28 | Jason Hammel | R | 25 | W 15-8 | @ BAL | 8 | 17 | - | 6.0 | 6 | 5 | 5 | 3 | 1 | 3 | 107 | 38 | 69 | 64% | 1-4 | 7.44 | 1.81 |
| 2007-08-29 | James Shields | R | 26 | W 5-4 | @ BAL | 28 | 49 | - | 8.0 | 10 | 4 | 4 | 1 | 2 | 6 | 112 | 42 | 70 | 63% | 10-8 | 4.10 | 1.14 |
| 2007-08-30 | Scott Kazmir | L | 24 | W 8-6 | @ BAL | 29 | 92 | W | 5.0 | 7 | 5 | 4 | 2 | 3 | 5 | 98 | 35 | 63 | 64% | 11-8 | 3.73 | 1.43 |
| 2007-08-31 | Andy Sonnanstine | R | 24 | W 9-1 | @ NYA | 17 | 17 | W | 8.0 | 2 | 1 | 0 | 0 | 0 | 5 | 103 | 31 | 72 | 70% | 4-9 | 5.88 | 1.29 |
| 2007-09-01 | Edwin Jackson | R | 24 | L 6-9 | @ NYA | 26 | 41 | L | 3.1 | 5 | 7 | 6 | 1 | 5 | 2 | 86 | 40 | 46 | 53% | 4-13 | 5.80 | 1.75 |
| 2007-09-02 | Jason Hammel | R | 25 | W 8-2 | @ NYA | 9 | 18 | W | 5.0 | 5 | 1 | 1 | 0 | 0 | 7 | 100 | 36 | 64 | 64% | 2-4 | 6.95 | 1.74 |
| 2007-09-03 | James Shields | R | 26 | L 9-7 | vs BAL | 29 | 50 | W | 7.0 | 7 | 4 | 1 | 0 | 1 | 6 | 96 | 31 | 65 | 68% | 11-8 | 4.01 | 1.14 |
| 2007-09-04 | Scott Kazmir | L | 24 | W 4-8 | vs BAL | 30 | 93 | - | 7.0 | 9 | 4 | 4 | 2 | 1 | 5 | 103 | 28 | 75 | 73% | 11-8 | 3.79 | 1.43 |
| 2007-09-05 | Andy Sonnanstine | R | 24 | L 17-2 | vs BAL | 18 | 18 | W | 6.0 | 9 | 2 | 2 | 0 | 0 | 6 | 82 | 25 | 57 | 70% | 5-9 | 5.73 | 1.30 |
| 2007-09-07 | Edwin Jackson | R | 24 | W 2-7 | vs TOR | 27 | 42 | L | 5.2 | 7 | 7 | 7 | 1 | 3 | 6 | 103 | 39 | 64 | 62% | 4-14 | 6.00 | 1.75 |
| 2007-09-08 | Jason Hammel | R | 25 | L 5-4 | vs TOR | 10 | 19 | - | 6.0 | 5 | 2 | 2 | 1 | 2 | 1 | 98 | 37 | 61 | 62% | 2-4 | 6.57 | 1.68 |
| 2007-09-09 | James Shields | R | 26 | L 3-2 | vs TOR | 30 | 51 | W | 7.0 | 4 | 2 | 2 | 1 | 0 | 5 | 106 | 36 | 70 | 66% | 12-8 | 3.96 | 1.12 |
| 2007-09-10 | Scott Kazmir | L | 24 | W 1-0 | @ BOS | 31 | 94 | W | 7.0 | 5 | 0 | 0 | 0 | 2 | 10 | 121 | 40 | 81 | 67% | 12-8 | 3.65 | 1.42 |
| 2007-09-11 | Andy Sonnanstine | R | 24 | L 10-16 | @ BOS | 19 | 19 | - | 3.1 | 8 | 5 | 5 | 1 | 1 | 3 | 80 | 30 | 50 | 63% | 5-9 | 5.97 | 1.35 |
| 2007-09-12 | Edwin Jackson | R | 24 | L 4-5 | @ BOS | 28 | 43 | - | 6.0 | 8 | 3 | 3 | 1 | 3 | 6 | 107 | 45 | 62 | 58% | 4-14 | 5.94 | 1.75 |
| 2007-09-13 | Jason Hammel | R | 25 | L 7-8 | @ SEA | 11 | 20 | - | 6.0 | 5 | 1 | 1 | 0 | 0 | 6 | 97 | 35 | 62 | 64% | 2-4 | 6.13 | 1.61 |
| 2007-09-14 | James Shields | R | 26 | L 1-2 | @ SEA | 31 | 52 | - | 8.0 | 4 | 1 | 1 | 0 | 2 | 5 | 99 | 36 | 63 | 64% | 12-8 | 3.85 | 1.11 |
| 2007-09-15 | Scott Kazmir | L | 24 | W 6-2 | @ SEA | 32 | 95 | W | 6.0 | 3 | 1 | 0 | 0 | 2 | 11 | 97 | 32 | 65 | 67% | 13-8 | 3.54 | 1.40 |
| 2007-09-16 | Andy Sonnanstine | R | 24 | W 9-2 | @ SEA | 20 | 20 | W | 7.0 | 6 | 1 | 1 | 1 | 2 | 8 | 97 | 28 | 69 | 71% | 6-9 | 5.70 | 1.33 |
| 2007-09-17 | Edwin Jackson | R | 24 | L 7-10 | @ ANA | 29 | 44 | L | 4.2 | 14 | 7 | 4 | 0 | 1 | 2 | 99 | 34 | 65 | 66% | 4-15 | 5.98 | 1.79 |
| 2007-09-18 | Jason Hammel | R | 25 | L 1-2 | @ ANA | 12 | 21 | L | 6.0 | 7 | 2 | 2 | 0 | 2 | 3 | 106 | 41 | 65 | 61% | 2-5 | 5.88 | 1.60 |
| 2007-09-19 | J.P. Howell | L | 24 | L 1-2 | @ ANA | 9 | 32 | L | 6.0 | 5 | 2 | 2 | 1 | 1 | 8 | 102 | 38 | 64 | 63% | 1-5 | 6.85 | 1.76 |
| 2007-09-21 | Scott Kazmir | L | 24 | W 1-8 | vs BOS | 33 | 96 | L | 5.0 | 4 | 3 | 2 | 0 | 4 | 9 | 90 | 37 | 53 | 59% | 13-9 | 3.54 | 1.40 |
| 2007-09-22 | Andy Sonnanstine | R | 25 | W 6-8 | vs BOS | 21 | 21 | - | 5.1 | 8 | 5 | 5 | 1 | 2 | 1 | 94 | 41 | 53 | 56% | 6-9 | 5.79 | 1.35 |
| 2007-09-23 | Edwin Jackson | R | 24 | L 5-4 | vs BOS | 30 | 45 | W | 5.1 | 5 | 3 | 3 | 0 | 3 | 5 | 105 | 39 | 66 | 63% | 5-15 | 5.96 | 1.79 |
| 2007-09-25 | Jason Hammel | R | 25 | L 7-6 | vs NYA | 13 | 22 | - | 5.0 | 7 | 5 | 5 | 1 | 3 | 4 | 101 | 47 | 54 | 53% | 2-5 | 6.08 | 1.63 |
| 2007-09-26 | J.P. Howell | L | 24 | W 4-12 | vs NYA | 10 | 33 | L | 4.2 | 6 | 9 | 8 | 2 | 3 | 4 | 93 | 38 | 55 | 59% | 1-6 | 7.59 | 1.76 |
| 2007-09-27 | Scott Kazmir | L | 24 | W 1-3 | vs NYA | 34 | 97 | - | 6.0 | 3 | 1 | 1 | 0 | 0 | 10 | 99 | 28 | 71 | 72% | 13-9 | 3.48 | 1.38 |
| 2007-09-28 | Andy Sonnanstine | R | 25 | L 4-5 | @ TOR | 22 | 22 | L | 5.0 | 6 | 4 | 4 | 1 | 1 | 4 | 80 | 25 | 55 | 69% | 6-10 | 5.84 | 1.35 |
| 2007-09-29 | Edwin Jackson | R | 24 | L 3-5 | @ TOR | 31 | 46 | - | 7.0 | 3 | 1 | 1 | 1 | 5 | 6 | 102 | 40 | 62 | 61% | 5-15 | 5.76 | 1.76 |
| 2007-09-30 | Jason Hammel | R | 25 | W 8-5 | @ TOR | 14 | 23 | W | 5.0 | 7 | 4 | 4 | 0 | 2 | 6 | 99 | 37 | 62 | 63% | 3-5 | 6.14 | 1.64 |