| Central | W | L | Pct | GB |
| St. Louis | 83 | 78 | .516 | -- |
| Houston | 82 | 80 | .506 | 1.5 |
| Cincinnati | 80 | 82 | .494 | 3.5 |
| Milwaukee | 75 | 87 | .463 | 8.5 |
| Pittsburgh | 67 | 95 | .414 | 16.5 |
| Chi Cubs | 66 | 96 | .407 | 17.5 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2006-04-03 | Carlos Zambrano | R | 25 | W 16-7 | @ CIN | 1 | 114 | - | 4.2 | 7 | 5 | 5 | 2 | 5 | 5 | 104 | 47 | 57 | 55% | 0-0 | 9.00 | 2.40 |
| 2006-04-05 | Glendon Rusch | L | 31 | L 6-8 | @ CIN | 1 | 203 | L | 4.0 | 6 | 4 | 4 | 2 | 2 | 2 | 88 | 40 | 48 | 55% | 0-1 | 9.00 | 2.00 |
| 2006-04-07 | Greg Maddux | R | 40 | L 5-1 | vs SLN | 1 | 640 | W | 6.1 | 4 | 1 | 1 | 1 | 2 | 1 | 87 | 35 | 52 | 60% | 1-0 | 1.50 | 1.00 |
| 2006-04-08 | Carlos Zambrano | R | 25 | L 3-2 | vs SLN | 2 | 115 | - | 6.0 | 4 | 2 | 0 | 0 | 4 | 5 | 111 | 46 | 65 | 59% | 0-0 | 4.09 | 1.82 |
| 2006-04-09 | Sean Marshall | L | 24 | L 8-4 | vs SLN | 1 | 1 | - | 4.1 | 4 | 4 | 4 | 1 | 1 | 2 | 65 | 23 | 42 | 65% | 0-0 | 9.00 | 1.25 |
| 2006-04-11 | Glendon Rusch | L | 31 | W 2-9 | vs CIN | 2 | 204 | L | 5.0 | 5 | 4 | 4 | 4 | 1 | 4 | 96 | 41 | 55 | 57% | 0-2 | 8.00 | 1.56 |
| 2006-04-12 | Greg Maddux | R | 40 | L 4-1 | vs CIN | 2 | 641 | W | 6.0 | 3 | 1 | 1 | 0 | 2 | 7 | 86 | 29 | 57 | 66% | 2-0 | 1.50 | 0.92 |
| 2006-04-13 | Carlos Zambrano | R | 25 | W 3-8 | vs CIN | 3 | 116 | L | 6.0 | 4 | 5 | 4 | 2 | 3 | 8 | 101 | 41 | 60 | 59% | 0-1 | 4.76 | 1.59 |
| 2006-04-14 | Sean Marshall | L | 24 | W 11-6 | @ PIT | 2 | 2 | W | 5.0 | 5 | 4 | 4 | 1 | 1 | 2 | 87 | 31 | 56 | 64% | 1-0 | 8.00 | 1.22 |
| 2006-04-15 | Jerome Williams | R | 24 | L 1-2 | @ PIT | 1 | 64 | L | 6.0 | 4 | 2 | 1 | 0 | 4 | 3 | 103 | 42 | 61 | 59% | 0-1 | 2.45 | 1.64 |
| 2006-04-16 | Glendon Rusch | L | 31 | W 7-3 | @ PIT | 3 | 205 | W | 6.0 | 5 | 3 | 3 | 1 | 1 | 5 | 88 | 26 | 62 | 70% | 1-2 | 6.60 | 1.33 |
| 2006-04-17 | Greg Maddux | R | 40 | W 4-1 | @ LAN | 3 | 642 | W | 8.0 | 3 | 1 | 1 | 0 | 0 | 6 | 86 | 28 | 58 | 67% | 3-0 | 1.35 | 0.70 |
| 2006-04-18 | Carlos Zambrano | R | 25 | L 1-2 | @ LAN | 4 | 117 | - | 6.0 | 4 | 1 | 1 | 0 | 5 | 3 | 112 | 49 | 63 | 56% | 0-1 | 3.91 | 1.57 |
| 2006-04-19 | Sean Marshall | L | 24 | W 5-4 | @ LAN | 3 | 3 | - | 5.0 | 2 | 2 | 2 | 1 | 3 | 4 | 86 | 35 | 51 | 59% | 1-0 | 6.43 | 1.14 |
| 2006-04-21 | Jerome Williams | R | 24 | L 3-9 | @ SLN | 2 | 65 | L | 1.1 | 6 | 7 | 7 | 1 | 2 | 0 | 53 | 21 | 32 | 60% | 0-2 | 7.50 | 2.17 |
| 2006-04-22 | Glendon Rusch | L | 31 | L 1-4 | @ SLN | 4 | 206 | L | 4.2 | 2 | 3 | 3 | 0 | 4 | 3 | 95 | 37 | 58 | 61% | 1-3 | 6.30 | 1.30 |
| 2006-04-23 | Greg Maddux | R | 40 | W 7-3 | @ SLN | 4 | 643 | W | 7.0 | 5 | 0 | 0 | 0 | 1 | 4 | 94 | 28 | 66 | 70% | 4-0 | 1.00 | 0.74 |
| 2006-04-24 | Carlos Zambrano | R | 25 | L 6-3 | vs FLO | 5 | 118 | - | 7.0 | 6 | 3 | 3 | 1 | 3 | 12 | 114 | 45 | 69 | 61% | 0-1 | 3.90 | 1.50 |
| 2006-04-25 | Sean Marshall | L | 24 | L 3-1 | vs FLO | 4 | 4 | W | 7.0 | 2 | 0 | 0 | 0 | 2 | 7 | 96 | 38 | 58 | 60% | 2-0 | 4.29 | 0.95 |
| 2006-04-26 | Angel Guzman | R | 24 | W 5-7 | vs FLO | 1 | 1 | - | 5.0 | 6 | 3 | 3 | 1 | 4 | 5 | 87 | 35 | 52 | 60% | 0-0 | 5.40 | 2.00 |
| 2006-04-28 | Greg Maddux | R | 40 | L 6-2 | vs MIL | 5 | 644 | W | 6.0 | 8 | 2 | 2 | 0 | 1 | 6 | 88 | 31 | 57 | 65% | 5-0 | 1.36 | 0.88 |
| 2006-04-29 | Glendon Rusch | L | 31 | W 2-16 | vs MIL | 5 | 207 | L | 2.2 | 6 | 7 | 7 | 4 | 3 | 0 | 81 | 38 | 43 | 53% | 1-4 | 8.59 | 1.59 |
| 2006-04-30 | Carlos Zambrano | R | 25 | W 0-9 | vs MIL | 6 | 119 | L | 4.0 | 8 | 7 | 7 | 1 | 5 | 5 | 103 | 44 | 59 | 57% | 0-2 | 5.29 | 1.71 |
| 2006-05-01 | Sean Marshall | L | 24 | L 2-1 | vs PIT | 5 | 5 | - | 7.1 | 4 | 1 | 1 | 0 | 1 | 5 | 89 | 33 | 56 | 63% | 2-0 | 3.41 | 0.86 |
| 2006-05-02 | Angel Guzman | R | 24 | W 0-8 | vs PIT | 2 | 2 | L | 5.2 | 6 | 6 | 4 | 1 | 3 | 7 | 104 | 34 | 70 | 67% | 0-1 | 5.73 | 1.73 |
| 2006-05-03 | Greg Maddux | R | 40 | L 1-5 | @ ARI | 6 | 645 | L | 5.0 | 10 | 5 | 5 | 1 | 0 | 5 | 87 | 32 | 55 | 63% | 5-1 | 2.37 | 1.03 |
| 2006-05-04 | Rich Hill | L | 26 | L 0-6 | @ ARI | 1 | 5 | L | 4.0 | 6 | 5 | 5 | 2 | 2 | 1 | 70 | 26 | 44 | 63% | 0-1 | 11.25 | 2.00 |
| 2006-05-05 | Carlos Zambrano | R | 25 | L 0-1 | @ SDN | 7 | 120 | - | 7.0 | 4 | 0 | 0 | 0 | 3 | 10 | 106 | 35 | 71 | 67% | 0-2 | 4.39 | 1.59 |
| 2006-05-06 | Sean Marshall | L | 24 | L 1-2 | @ SDN | 6 | 6 | - | 6.0 | 3 | 1 | 1 | 0 | 3 | 6 | 94 | 44 | 50 | 53% | 2-0 | 3.09 | 0.89 |
| 2006-05-07 | Angel Guzman | R | 24 | L 3-6 | @ SDN | 3 | 3 | L | 4.1 | 5 | 5 | 5 | 0 | 4 | 4 | 106 | 50 | 56 | 53% | 0-2 | 7.20 | 1.87 |
| 2006-05-08 | Greg Maddux | R | 40 | L 3-8 | @ SDN | 7 | 646 | L | 3.2 | 9 | 7 | 7 | 1 | 2 | 4 | 75 | 27 | 48 | 64% | 5-2 | 3.64 | 1.19 |
| 2006-05-09 | Rich Hill | L | 26 | L 1-6 | @ SFN | 2 | 6 | L | 6.0 | 8 | 5 | 5 | 1 | 3 | 4 | 99 | 40 | 59 | 60% | 0-2 | 9.00 | 1.90 |
| 2006-05-10 | Carlos Zambrano | R | 25 | W 8-1 | @ SFN | 8 | 121 | W | 8.0 | 5 | 1 | 1 | 0 | 5 | 6 | 109 | 47 | 62 | 57% | 1-2 | 3.86 | 1.53 |
| 2006-05-11 | Sean Marshall | L | 24 | L 3-9 | @ SFN | 7 | 7 | L | 3.2 | 9 | 9 | 9 | 0 | 5 | 2 | 88 | 40 | 48 | 55% | 2-1 | 4.97 | 1.18 |
| 2006-05-12 | Angel Guzman | R | 24 | W 5-10 | vs SDN | 4 | 4 | - | 3.0 | 3 | 2 | 2 | 0 | 5 | 4 | 87 | 37 | 50 | 57% | 0-2 | 7.00 | 2.00 |
| 2006-05-13 | Greg Maddux | R | 40 | W 3-4 | vs SDN | 8 | 647 | - | 7.1 | 4 | 1 | 0 | 0 | 1 | 3 | 73 | 25 | 48 | 66% | 5-2 | 3.12 | 1.12 |
| 2006-05-14 | Rich Hill | L | 26 | W 0-9 | vs SDN | 3 | 7 | L | 5.1 | 4 | 3 | 3 | 0 | 5 | 4 | 90 | 37 | 53 | 59% | 0-3 | 7.80 | 1.87 |
| 2006-05-16 | Carlos Zambrano | R | 25 | L 4-0 | vs WAS | 9 | 122 | W | 8.0 | 4 | 0 | 0 | 0 | 2 | 8 | 122 | 48 | 74 | 61% | 2-2 | 3.32 | 1.42 |
| 2006-05-17 | Sean Marshall | L | 24 | L 5-0 | vs WAS | 8 | 8 | W | 6.0 | 1 | 0 | 0 | 0 | 4 | 6 | 99 | 44 | 55 | 56% | 3-1 | 4.30 | 1.14 |
| 2006-05-18 | Kerry Wood | R | 29 | W 3-5 | vs WAS | 1 | 175 | L | 5.0 | 5 | 4 | 4 | 3 | 0 | 6 | 70 | 19 | 51 | 73% | 0-1 | 7.20 | 1.00 |
| 2006-05-19 | Greg Maddux | R | 40 | L 1-6 | @ CHA | 9 | 648 | L | 5.2 | 9 | 6 | 6 | 1 | 5 | 1 | 102 | 49 | 53 | 52% | 5-3 | 3.76 | 1.25 |
| 2006-05-20 | Rich Hill | L | 26 | L 0-7 | @ CHA | 4 | 8 | L | 4.0 | 5 | 7 | 7 | 2 | 5 | 2 | 91 | 46 | 45 | 49% | 0-4 | 9.47 | 2.00 |
| 2006-05-21 | Carlos Zambrano | R | 25 | W 7-4 | @ CHA | 10 | 123 | W | 7.0 | 4 | 4 | 4 | 3 | 3 | 9 | 118 | 53 | 65 | 55% | 3-2 | 3.52 | 1.38 |
| 2006-05-22 | Sean Marshall | L | 24 | L 1-9 | @ FLO | 9 | 9 | L | 3.1 | 7 | 7 | 7 | 1 | 4 | 2 | 69 | 34 | 35 | 51% | 3-2 | 5.25 | 1.27 |
| 2006-05-23 | Kerry Wood | R | 29 | L 4-5 | @ FLO | 2 | 176 | - | 5.0 | 2 | 3 | 3 | 1 | 5 | 3 | 91 | 39 | 52 | 57% | 0-1 | 6.30 | 1.20 |
| 2006-05-24 | Greg Maddux | R | 40 | L 3-9 | @ FLO | 10 | 649 | L | 6.0 | 7 | 6 | 1 | 1 | 2 | 4 | 97 | 34 | 63 | 65% | 5-4 | 3.54 | 1.28 |
| 2006-05-26 | Carlos Zambrano | R | 25 | W 5-6 | vs ATL | 11 | 124 | - | 6.2 | 2 | 2 | 2 | 0 | 6 | 8 | 123 | 50 | 73 | 59% | 3-2 | 3.47 | 1.37 |
| 2006-05-27 | Sean Marshall | L | 24 | W 1-2 | vs ATL | 10 | 10 | L | 6.0 | 7 | 2 | 2 | 0 | 2 | 2 | 93 | 34 | 59 | 63% | 3-3 | 5.00 | 1.30 |
| 2006-05-28 | Jae-Kuk Ryu | R | 23 | W 12-13 | vs ATL | 1 | 1 | - | 1.1 | 7 | 6 | 6 | 4 | 0 | 0 | 28 | 8 | 20 | 71% | 0-0 | 31.50 | 5.00 |
| 2006-05-29 | Kerry Wood | R | 29 | L 7-3 | vs CIN | 3 | 177 | W | 6.0 | 5 | 2 | 1 | 0 | 1 | 4 | 85 | 29 | 56 | 66% | 1-1 | 4.50 | 1.13 |
| 2006-05-30 | Greg Maddux | R | 40 | L 8-3 | vs CIN | 11 | 650 | W | 5.2 | 7 | 3 | 3 | 0 | 0 | 1 | 64 | 14 | 50 | 78% | 6-4 | 3.63 | 1.27 |
| 2006-05-31 | Carlos Zambrano | R | 25 | W 2-3 | vs CIN | 12 | 125 | L | 6.0 | 4 | 2 | 2 | 1 | 3 | 6 | 100 | 44 | 56 | 56% | 3-3 | 3.43 | 1.36 |
| 2006-06-02 | Sean Marshall | L | 24 | W 5-4 | @ SLN | 11 | 11 | - | 6.1 | 8 | 2 | 2 | 0 | 1 | 4 | 95 | 37 | 58 | 61% | 3-3 | 4.80 | 1.32 |
| 2006-06-03 | Glendon Rusch | L | 32 | W 8-5 | @ SLN | 6 | 208 | W | 5.0 | 4 | 3 | 3 | 0 | 2 | 5 | 90 | 31 | 59 | 66% | 2-5 | 6.86 | 1.50 |
| 2006-06-04 | Greg Maddux | R | 40 | L 6-9 | @ SLN | 12 | 651 | L | 5.0 | 9 | 6 | 6 | 0 | 2 | 0 | 78 | 29 | 49 | 63% | 6-5 | 4.13 | 1.33 |
| 2006-06-05 | Carlos Zambrano | R | 25 | W 8-0 | @ HOU | 13 | 126 | W | 8.0 | 1 | 0 | 0 | 0 | 2 | 8 | 128 | 55 | 73 | 57% | 4-3 | 3.11 | 1.26 |
| 2006-06-06 | Kerry Wood | R | 29 | L 1-4 | @ HOU | 4 | 178 | L | 3.2 | 7 | 4 | 1 | 1 | 2 | 0 | 75 | 25 | 50 | 67% | 1-2 | 4.05 | 1.35 |
| 2006-06-07 | Sean Marshall | L | 24 | L 0-1 | @ HOU | 12 | 12 | L | 7.0 | 4 | 1 | 1 | 1 | 3 | 5 | 86 | 37 | 49 | 57% | 3-4 | 4.43 | 1.28 |
| 2006-06-08 | Glendon Rusch | L | 32 | L 1-7 | @ CIN | 7 | 209 | L | 3.2 | 7 | 5 | 5 | 3 | 1 | 5 | 78 | 31 | 47 | 60% | 2-6 | 7.24 | 1.54 |
| 2006-06-09 | Greg Maddux | R | 40 | W 6-5 | @ CIN | 13 | 652 | W | 5.1 | 4 | 2 | 2 | 2 | 0 | 2 | 66 | 23 | 43 | 65% | 7-5 | 4.09 | 1.30 |
| 2006-06-10 | Carlos Zambrano | R | 25 | W 4-2 | @ CIN | 14 | 127 | W | 7.2 | 4 | 1 | 1 | 1 | 6 | 4 | 126 | 57 | 69 | 55% | 5-3 | 2.93 | 1.26 |
| 2006-06-11 | Carlos Marmol | R | 24 | W 9-3 | @ CIN | 1 | 1 | W | 6.0 | 2 | 1 | 1 | 1 | 3 | 7 | 98 | 34 | 64 | 65% | 1-0 | 0.90 | 0.80 |
| 2006-06-13 | Sean Marshall | L | 24 | W 2-9 | vs HOU | 13 | 13 | L | 4.0 | 7 | 5 | 5 | 1 | 4 | 1 | 88 | 41 | 47 | 53% | 3-5 | 4.82 | 1.37 |
| 2006-06-14 | Greg Maddux | R | 40 | W 4-5 | vs HOU | 14 | 653 | L | 7.0 | 11 | 5 | 5 | 0 | 0 | 1 | 90 | 24 | 66 | 73% | 7-6 | 4.29 | 1.32 |
| 2006-06-15 | Carlos Zambrano | R | 25 | W 2-3 | vs HOU | 15 | 128 | - | 7.0 | 5 | 1 | 1 | 0 | 2 | 5 | 106 | 39 | 67 | 63% | 5-3 | 2.82 | 1.24 |
| 2006-06-16 | Glendon Rusch | L | 32 | W 3-5 | vs DET | 8 | 210 | L | 1.2 | 6 | 4 | 4 | 1 | 0 | 2 | 54 | 20 | 34 | 63% | 2-7 | 7.85 | 1.64 |
| 2006-06-17 | Carlos Marmol | R | 24 | W 3-9 | vs DET | 2 | 2 | L | 6.0 | 7 | 4 | 4 | 1 | 2 | 4 | 85 | 37 | 48 | 56% | 1-1 | 2.81 | 1.06 |
| 2006-06-18 | Mark Prior | R | 26 | W 3-12 | vs DET | 1 | 98 | L | 3.2 | 7 | 8 | 7 | 4 | 1 | 2 | 88 | 35 | 53 | 60% | 0-1 | 15.75 | 2.00 |
| 2006-06-19 | Sean Marshall | L | 24 | W 12-8 | @ CLE | 14 | 14 | W | 5.0 | 7 | 4 | 4 | 3 | 2 | 2 | 91 | 42 | 49 | 54% | 4-5 | 4.97 | 1.39 |
| 2006-06-20 | Greg Maddux | R | 40 | L 2-4 | @ CLE | 15 | 654 | L | 7.1 | 7 | 4 | 4 | 1 | 1 | 4 | 109 | 35 | 74 | 68% | 7-7 | 4.35 | 1.31 |
| 2006-06-21 | Carlos Zambrano | R | 25 | W 9-2 | @ CLE | 16 | 129 | W | 6.0 | 6 | 2 | 2 | 0 | 3 | 2 | 100 | 37 | 63 | 63% | 6-3 | 2.83 | 1.26 |
| 2006-06-23 | Carlos Marmol | R | 24 | L 2-7 | @ MIN | 3 | 3 | L | 5.2 | 6 | 7 | 7 | 1 | 4 | 3 | 107 | 51 | 56 | 52% | 1-2 | 4.91 | 1.23 |
| 2006-06-24 | Mark Prior | R | 26 | L 0-3 | @ MIN | 2 | 99 | L | 5.2 | 8 | 3 | 3 | 0 | 1 | 4 | 91 | 34 | 57 | 63% | 0-2 | 10.00 | 1.89 |
| 2006-06-25 | Sean Marshall | L | 24 | L 1-8 | @ MIN | 15 | 15 | L | 4.2 | 6 | 5 | 4 | 0 | 3 | 3 | 94 | 40 | 54 | 57% | 4-6 | 5.11 | 1.42 |
| 2006-06-26 | Greg Maddux | R | 40 | W 0-6 | vs MIL | 16 | 655 | L | 7.0 | 7 | 5 | 5 | 3 | 0 | 7 | 89 | 26 | 63 | 71% | 7-8 | 4.50 | 1.29 |
| 2006-06-27 | Carlos Zambrano | R | 25 | W 5-8 | vs MIL | 17 | 130 | - | 8.0 | 6 | 4 | 4 | 1 | 2 | 8 | 119 | 45 | 74 | 62% | 6-3 | 2.95 | 1.24 |
| 2006-06-28 | Carlos Marmol | R | 24 | L 6-3 | vs MIL | 4 | 4 | - | 6.1 | 3 | 1 | 1 | 0 | 2 | 8 | 95 | 43 | 52 | 55% | 1-2 | 4.18 | 1.14 |
| 2006-06-29 | Mark Prior | R | 26 | W 4-5 | vs MIL | 3 | 100 | L | 5.2 | 8 | 5 | 5 | 1 | 4 | 9 | 100 | 42 | 58 | 58% | 0-3 | 9.00 | 1.93 |
| 2006-06-30 | Sean Marshall | L | 24 | W 2-6 | vs CHA | 16 | 16 | L | 6.0 | 8 | 4 | 4 | 0 | 3 | 6 | 98 | 41 | 57 | 58% | 4-7 | 5.17 | 1.45 |
| 2006-07-01 | Greg Maddux | R | 40 | W 6-8 | vs CHA | 17 | 656 | - | 6.0 | 10 | 4 | 4 | 2 | 0 | 3 | 78 | 26 | 52 | 67% | 7-8 | 4.59 | 1.31 |
| 2006-07-02 | Carlos Zambrano | R | 25 | L 15-11 | vs CHA | 18 | 131 | W | 6.0 | 7 | 7 | 7 | 2 | 3 | 6 | 109 | 49 | 60 | 55% | 7-3 | 3.33 | 1.26 |
| 2006-07-03 | Carlos Marmol | R | 24 | L 2-7 | @ HOU | 5 | 5 | L | 4.1 | 5 | 4 | 4 | 2 | 7 | 1 | 90 | 45 | 45 | 50% | 1-3 | 4.78 | 1.38 |
| 2006-07-04 | Mark Prior | R | 26 | L 2-7 | @ HOU | 4 | 101 | L | 6.0 | 4 | 4 | 3 | 0 | 4 | 7 | 112 | 52 | 60 | 54% | 0-4 | 7.71 | 1.76 |
| 2006-07-05 | Sean Marshall | L | 24 | W 1-0 | @ HOU | 17 | 17 | W | 7.0 | 6 | 0 | 0 | 0 | 3 | 2 | 102 | 46 | 56 | 55% | 5-7 | 4.79 | 1.44 |
| 2006-07-06 | Greg Maddux | R | 40 | L 0-2 | @ MIL | 18 | 657 | L | 6.0 | 6 | 2 | 2 | 0 | 1 | 3 | 81 | 29 | 52 | 64% | 7-9 | 4.50 | 1.30 |
| 2006-07-07 | Carlos Zambrano | R | 25 | W 7-2 | @ MIL | 19 | 132 | W | 6.0 | 5 | 1 | 1 | 0 | 3 | 6 | 112 | 38 | 74 | 66% | 8-3 | 3.24 | 1.26 |
| 2006-07-08 | Carlos Marmol | R | 24 | W 3-1 | @ MIL | 6 | 6 | W | 6.0 | 3 | 1 | 1 | 0 | 5 | 4 | 104 | 42 | 62 | 60% | 2-3 | 4.26 | 1.37 |
| 2006-07-09 | Glendon Rusch | L | 32 | W 11-4 | @ MIL | 9 | 211 | W | 5.0 | 4 | 2 | 2 | 1 | 2 | 5 | 83 | 28 | 55 | 66% | 3-7 | 7.81 | 1.68 |
| 2006-07-14 | Greg Maddux | R | 40 | W 3-6 | vs NYN | 19 | 658 | L | 7.0 | 8 | 6 | 5 | 0 | 2 | 6 | 98 | 34 | 64 | 65% | 7-10 | 4.62 | 1.31 |
| 2006-07-15 | Carlos Zambrano | R | 25 | L 9-2 | vs NYN | 20 | 133 | W | 6.0 | 3 | 2 | 2 | 0 | 4 | 7 | 103 | 44 | 59 | 57% | 9-3 | 3.23 | 1.26 |
| 2006-07-16 | Sean Marshall | L | 24 | W 7-13 | vs NYN | 18 | 18 | L | 5.1 | 7 | 7 | 5 | 3 | 1 | 4 | 88 | 23 | 65 | 74% | 5-8 | 5.00 | 1.44 |
| 2006-07-18 | Carlos Marmol | R | 24 | L 4-2 | vs HOU | 7 | 7 | W | 6.0 | 4 | 1 | 1 | 0 | 6 | 6 | 110 | 45 | 65 | 59% | 3-3 | 3.89 | 1.41 |
| 2006-07-19 | Greg Maddux | R | 40 | W 2-4 | vs HOU | 20 | 659 | L | 7.0 | 7 | 3 | 3 | 1 | 0 | 3 | 102 | 32 | 70 | 69% | 7-11 | 4.57 | 1.29 |
| 2006-07-20 | Carlos Zambrano | R | 25 | L 4-1 | vs HOU | 21 | 134 | W | 8.0 | 2 | 1 | 1 | 0 | 4 | 10 | 123 | 51 | 72 | 59% | 10-3 | 3.11 | 1.23 |
| 2006-07-21 | Mark Prior | R | 26 | L 6-7 | @ WAS | 5 | 102 | - | 3.1 | 4 | 4 | 4 | 0 | 3 | 2 | 84 | 41 | 43 | 51% | 0-4 | 8.25 | 1.83 |
| 2006-07-22 | Sean Marshall | L | 24 | L 3-7 | @ WAS | 19 | 19 | - | 4.0 | 6 | 2 | 2 | 1 | 0 | 2 | 63 | 23 | 40 | 63% | 5-8 | 4.98 | 1.45 |
| 2006-07-23 | Carlos Marmol | R | 24 | L 1-7 | @ WAS | 8 | 8 | L | 3.2 | 6 | 5 | 5 | 2 | 4 | 2 | 72 | 37 | 35 | 49% | 3-4 | 4.50 | 1.50 |
| 2006-07-24 | Greg Maddux | R | 40 | W 8-7 | @ NYN | 21 | 660 | W | 6.0 | 10 | 7 | 7 | 0 | 1 | 4 | 88 | 25 | 63 | 72% | 8-11 | 4.85 | 1.32 |
| 2006-07-25 | Carlos Zambrano | R | 25 | W 8-6 | @ NYN | 22 | 135 | W | 7.0 | 8 | 5 | 5 | 2 | 1 | 6 | 100 | 35 | 65 | 65% | 11-3 | 3.27 | 1.23 |
| 2006-07-26 | Mark Prior | R | 26 | L 0-1 | @ NYN | 6 | 103 | - | 5.2 | 0 | 0 | 0 | 0 | 5 | 3 | 105 | 48 | 57 | 54% | 0-4 | 6.60 | 1.63 |
| 2006-07-27 | Rich Hill | L | 26 | L 5-4 | vs SLN | 5 | 9 | - | 3.1 | 6 | 4 | 4 | 1 | 3 | 1 | 82 | 35 | 47 | 57% | 0-4 | 9.39 | 2.04 |
| 2006-07-28 | Carlos Marmol | R | 24 | L 6-5 | vs SLN | 9 | 9 | W | 5.1 | 3 | 3 | 2 | 0 | 7 | 5 | 110 | 54 | 56 | 51% | 4-4 | 4.42 | 1.55 |
| 2006-07-29 | Greg Maddux | R | 40 | L 4-2 | vs SLN | 22 | 661 | W | 6.0 | 5 | 1 | 1 | 0 | 0 | 6 | 84 | 21 | 63 | 75% | 9-11 | 4.70 | 1.29 |
| 2006-07-30 | Carlos Zambrano | R | 25 | L 6-3 | vs SLN | 23 | 136 | W | 6.0 | 5 | 2 | 2 | 0 | 5 | 5 | 110 | 49 | 61 | 55% | 12-3 | 3.26 | 1.25 |
| 2006-07-31 | Mark Prior | R | 26 | W 4-15 | vs ARI | 7 | 104 | L | 5.0 | 6 | 6 | 6 | 3 | 3 | 5 | 106 | 47 | 59 | 56% | 0-5 | 7.20 | 1.66 |
| 2006-08-01 | Rich Hill | L | 26 | L 9-3 | vs ARI | 6 | 10 | W | 8.0 | 6 | 3 | 3 | 1 | 1 | 6 | 109 | 35 | 74 | 68% | 1-4 | 7.84 | 1.74 |
| 2006-08-03 | Carlos Marmol | R | 24 | W 2-10 | vs ARI | 10 | 10 | L | 5.0 | 7 | 7 | 7 | 1 | 3 | 2 | 97 | 42 | 55 | 57% | 4-5 | 5.12 | 1.59 |
| 2006-08-03 | Juan Mateo | R | 24 | L 7-3 | vs ARI | 1 | 1 | W | 5.0 | 6 | 3 | 2 | 0 | 3 | 2 | 88 | 34 | 54 | 61% | 1-0 | 3.60 | 1.80 |
| 2006-08-04 | Carlos Zambrano | R | 25 | W 0-6 | vs PIT | 24 | 137 | L | 6.0 | 9 | 5 | 5 | 1 | 3 | 6 | 117 | 40 | 77 | 66% | 12-4 | 3.42 | 1.28 |
| 2006-08-05 | Mark Prior | R | 26 | L 7-5 | vs PIT | 8 | 105 | W | 5.2 | 5 | 3 | 2 | 1 | 3 | 5 | 103 | 39 | 64 | 62% | 1-5 | 6.59 | 1.61 |
| 2006-08-06 | Rich Hill | L | 26 | L 6-1 | vs PIT | 7 | 11 | W | 7.0 | 5 | 1 | 1 | 1 | 2 | 9 | 103 | 35 | 68 | 66% | 2-4 | 6.63 | 1.61 |
| 2006-08-08 | Carlos Marmol | R | 24 | W 6-3 | @ MIL | 11 | 11 | W | 5.1 | 4 | 3 | 3 | 2 | 4 | 3 | 98 | 45 | 53 | 54% | 5-5 | 5.06 | 1.56 |
| 2006-08-09 | Carlos Zambrano | R | 25 | L 3-6 | @ MIL | 25 | 138 | L | 4.2 | 5 | 6 | 4 | 1 | 4 | 4 | 108 | 42 | 66 | 61% | 12-5 | 3.53 | 1.29 |
| 2006-08-10 | Mark Prior | R | 26 | L 6-8 | @ MIL | 9 | 106 | L | 3.0 | 4 | 6 | 5 | 0 | 4 | 1 | 62 | 28 | 34 | 55% | 1-6 | 7.16 | 1.68 |
| 2006-08-11 | Rich Hill | L | 26 | L 2-10 | @ COL | 8 | 12 | L | 4.2 | 6 | 6 | 6 | 1 | 5 | 2 | 97 | 42 | 55 | 57% | 2-5 | 7.29 | 1.71 |
| 2006-08-12 | Angel Guzman | R | 25 | L 4-8 | @ COL | 5 | 5 | L | 2.2 | 9 | 7 | 7 | 1 | 2 | 1 | 70 | 30 | 40 | 57% | 0-3 | 7.39 | 1.96 |
| 2006-08-13 | Carlos Marmol | R | 24 | W 8-7 | @ COL | 12 | 12 | - | 5.0 | 5 | 6 | 6 | 1 | 8 | 1 | 111 | 56 | 55 | 50% | 5-5 | 5.48 | 1.64 |
| 2006-08-14 | Carlos Zambrano | R | 25 | W 3-0 | @ HOU | 26 | 139 | W | 8.0 | 4 | 0 | 0 | 0 | 7 | 5 | 123 | 57 | 66 | 54% | 13-5 | 3.37 | 1.30 |
| 2006-08-15 | Juan Mateo | R | 24 | W 8-6 | @ HOU | 2 | 2 | - | 5.0 | 4 | 2 | 2 | 0 | 1 | 2 | 78 | 24 | 54 | 69% | 1-0 | 3.00 | 1.50 |
| 2006-08-16 | Ryan O'Malley | L | 26 | W 1-0 | @ HOU | 1 | 1 | W | 8.0 | 5 | 0 | 0 | 0 | 6 | 2 | 109 | 49 | 60 | 55% | 1-0 | 0.00 | 1.38 |
| 2006-08-18 | Carlos Marmol | R | 24 | W 3-11 | vs SLN | 13 | 13 | L | 3.0 | 6 | 4 | 3 | 1 | 0 | 0 | 61 | 24 | 37 | 61% | 5-6 | 5.63 | 1.65 |
| 2006-08-19 | Carlos Zambrano | R | 25 | L 5-4 | vs SLN | 27 | 140 | - | 7.0 | 6 | 2 | 2 | 1 | 2 | 6 | 109 | 41 | 68 | 62% | 13-5 | 3.34 | 1.29 |
| 2006-08-20 | Juan Mateo | R | 24 | W 3-5 | vs SLN | 3 | 3 | L | 7.0 | 7 | 4 | 4 | 2 | 3 | 5 | 101 | 33 | 68 | 67% | 1-1 | 3.79 | 1.47 |
| 2006-08-21 | Rich Hill | L | 26 | W 5-6 | vs PHI | 9 | 13 | L | 6.0 | 5 | 5 | 2 | 2 | 3 | 6 | 112 | 45 | 67 | 60% | 3-6 | 6.48 | 1.62 |
| 2006-08-22 | Ryan O'Malley | L | 26 | W 3-6 | vs PHI | 2 | 2 | L | 4.2 | 5 | 3 | 3 | 0 | 1 | 2 | 75 | 24 | 51 | 68% | 1-1 | 2.08 | 1.31 |
| 2006-08-23 | Angel Guzman | R | 25 | W 1-2 | vs PHI | 6 | 6 | - | 6.0 | 4 | 1 | 1 | 1 | 3 | 8 | 94 | 40 | 54 | 57% | 0-3 | 5.84 | 1.76 |
| 2006-08-24 | Carlos Zambrano | R | 25 | L 11-2 | vs PHI | 28 | 141 | W | 7.0 | 6 | 2 | 2 | 0 | 1 | 7 | 102 | 36 | 66 | 65% | 14-5 | 3.31 | 1.28 |
| 2006-08-25 | Juan Mateo | R | 24 | L 0-2 | @ SLN | 4 | 4 | L | 5.0 | 10 | 2 | 1 | 0 | 1 | 2 | 96 | 38 | 58 | 60% | 1-2 | 3.38 | 1.63 |
| 2006-08-26 | Rich Hill | L | 26 | L 1-2 | @ SLN | 10 | 14 | - | 7.0 | 4 | 1 | 1 | 1 | 0 | 2 | 94 | 33 | 61 | 65% | 3-6 | 5.84 | 1.49 |
| 2006-08-27 | Les Walrond | L | 30 | L 6-10 | @ SLN | 1 | 1 | - | 2.2 | 7 | 5 | 5 | 0 | 3 | 1 | 73 | 39 | 34 | 47% | 0-0 | 15.00 | 3.33 |
| 2006-08-28 | Angel Guzman | R | 25 | L 6-11 | @ PIT | 7 | 7 | L | 3.0 | 10 | 8 | 8 | 1 | 2 | 5 | 98 | 39 | 59 | 60% | 0-4 | 7.20 | 1.93 |
| 2006-08-29 | Carlos Zambrano | R | 25 | L 6-7 | @ PIT | 29 | 142 | - | 7.0 | 7 | 5 | 3 | 0 | 1 | 7 | 110 | 38 | 72 | 65% | 14-5 | 3.33 | 1.28 |
| 2006-08-30 | Juan Mateo | R | 24 | L 9-10 | @ PIT | 5 | 5 | - | 2.0 | 4 | 3 | 3 | 0 | 1 | 2 | 55 | 20 | 35 | 64% | 1-2 | 4.15 | 1.69 |
| 2006-09-01 | Rich Hill | L | 26 | L 6-2 | vs SFN | 11 | 15 | W | 8.0 | 5 | 1 | 1 | 0 | 1 | 6 | 106 | 31 | 75 | 71% | 4-6 | 5.26 | 1.40 |
| 2006-09-02 | Sean Marshall | L | 24 | W 2-4 | vs SFN | 20 | 20 | L | 5.2 | 5 | 4 | 4 | 3 | 2 | 1 | 90 | 38 | 52 | 58% | 5-9 | 5.04 | 1.43 |
| 2006-09-03 | Angel Guzman | R | 25 | W 4-7 | vs SFN | 8 | 8 | - | 4.2 | 3 | 3 | 3 | 0 | 2 | 4 | 78 | 28 | 50 | 64% | 0-4 | 7.00 | 1.82 |
| 2006-09-04 | Carlos Zambrano | R | 25 | W 4-5 | vs PIT | 30 | 143 | L | 1.1 | 4 | 5 | 4 | 0 | 4 | 1 | 43 | 20 | 23 | 53% | 14-6 | 3.50 | 1.31 |
| 2006-09-05 | Juan Mateo | R | 24 | W 5-6 | vs PIT | 6 | 6 | - | 4.0 | 6 | 5 | 5 | 2 | 0 | 7 | 68 | 19 | 49 | 72% | 1-2 | 5.10 | 1.67 |
| 2006-09-06 | Rich Hill | L | 26 | L 7-2 | vs PIT | 12 | 16 | - | 7.1 | 4 | 2 | 1 | 0 | 2 | 11 | 109 | 39 | 70 | 64% | 4-6 | 4.81 | 1.33 |
| 2006-09-07 | Sean Marshall | L | 24 | W 5-7 | vs PIT | 21 | 21 | - | 4.0 | 7 | 5 | 5 | 1 | 2 | 1 | 69 | 26 | 43 | 62% | 5-9 | 5.26 | 1.46 |
| 2006-09-08 | Angel Guzman | R | 25 | L 4-8 | @ ATL | 9 | 9 | L | 4.1 | 7 | 6 | 6 | 3 | 0 | 7 | 79 | 28 | 51 | 65% | 0-5 | 7.53 | 1.82 |
| 2006-09-09 | Wade Miller | R | 30 | L 3-7 | @ ATL | 1 | 140 | L | 3.0 | 5 | 4 | 4 | 2 | 5 | 3 | 73 | 38 | 35 | 48% | 0-1 | 12.00 | 3.33 |
| 2006-09-10 | Juan Mateo | R | 24 | L 1-2 | @ ATL | 7 | 7 | L | 6.0 | 5 | 2 | 2 | 0 | 2 | 6 | 97 | 33 | 64 | 66% | 1-3 | 4.75 | 1.58 |
| 2006-09-11 | Rich Hill | L | 27 | W 8-3 | @ ATL | 13 | 17 | W | 5.2 | 6 | 2 | 1 | 0 | 2 | 6 | 119 | 40 | 79 | 66% | 5-6 | 4.62 | 1.35 |
| 2006-09-12 | Sean Marshall | L | 24 | L 9-8 | vs LAN | 22 | 22 | - | 3.2 | 6 | 7 | 3 | 1 | 4 | 2 | 79 | 35 | 44 | 56% | 5-9 | 5.35 | 1.51 |
| 2006-09-13 | Angel Guzman | R | 25 | W 0-6 | vs LAN | 10 | 10 | L | 4.0 | 8 | 5 | 5 | 1 | 4 | 1 | 81 | 39 | 42 | 52% | 0-6 | 7.81 | 1.91 |
| 2006-09-14 | Wade Miller | R | 30 | L 6-5 | vs LAN | 2 | 141 | - | 5.0 | 1 | 2 | 2 | 1 | 3 | 3 | 81 | 32 | 49 | 60% | 0-1 | 6.75 | 1.75 |
| 2006-09-15 | Juan Mateo | R | 24 | W 0-4 | vs CIN | 8 | 8 | - | 3.0 | 0 | 0 | 0 | 0 | 2 | 3 | 40 | 17 | 23 | 58% | 1-3 | 4.38 | 1.51 |
| 2006-09-16 | Rich Hill | L | 27 | L 4-0 | vs CIN | 14 | 18 | W | 9.0 | 2 | 0 | 0 | 0 | 1 | 10 | 118 | 33 | 85 | 72% | 6-6 | 4.14 | 1.24 |
| 2006-09-17 | Carlos Zambrano | R | 25 | L 11-3 | vs CIN | 31 | 144 | W | 7.0 | 4 | 0 | 0 | 0 | 4 | 6 | 108 | 42 | 66 | 61% | 15-6 | 3.38 | 1.31 |
| 2006-09-18 | Sean Marshall | L | 24 | W 11-6 | @ PHI | 23 | 23 | - | 3.1 | 5 | 6 | 6 | 1 | 2 | 3 | 60 | 29 | 31 | 52% | 5-9 | 5.63 | 1.52 |
| 2006-09-19 | Wade Miller | R | 30 | L 1-4 | @ PHI | 3 | 142 | L | 4.2 | 4 | 2 | 1 | 0 | 4 | 8 | 96 | 47 | 49 | 51% | 0-2 | 4.85 | 1.69 |
| 2006-09-20 | Les Walrond | L | 30 | L 2-6 | @ PHI | 2 | 2 | L | 3.0 | 3 | 2 | 2 | 0 | 5 | 6 | 74 | 37 | 37 | 50% | 0-1 | 7.07 | 2.07 |
| 2006-09-22 | Rich Hill | L | 27 | L 2-4 | @ CIN | 15 | 19 | L | 5.0 | 4 | 4 | 4 | 3 | 2 | 10 | 98 | 35 | 63 | 64% | 6-7 | 4.30 | 1.24 |
| 2006-09-23 | Carlos Zambrano | R | 25 | W 11-4 | @ CIN | 32 | 145 | W | 7.0 | 6 | 4 | 4 | 1 | 3 | 7 | 111 | 46 | 65 | 59% | 16-6 | 3.43 | 1.30 |
| 2006-09-24 | Juan Mateo | R | 24 | L 2-3 | @ CIN | 9 | 9 | - | 5.0 | 3 | 1 | 1 | 0 | 4 | 4 | 86 | 40 | 46 | 53% | 1-3 | 4.09 | 1.50 |
| 2006-09-25 | Wade Miller | R | 30 | L 4-5 | @ CIN | 4 | 143 | - | 5.0 | 3 | 0 | 0 | 0 | 3 | 2 | 85 | 42 | 43 | 51% | 0-2 | 3.50 | 1.56 |
| 2006-09-26 | Sean Marshall | L | 24 | L 14-6 | vs MIL | 24 | 24 | W | 6.0 | 6 | 3 | 3 | 1 | 3 | 3 | 94 | 43 | 51 | 54% | 6-9 | 5.57 | 1.52 |
| 2006-09-27 | Rich Hill | L | 27 | L 3-2 | vs MIL | 16 | 20 | - | 7.0 | 6 | 2 | 2 | 1 | 2 | 7 | 115 | 38 | 77 | 67% | 6-7 | 4.18 | 1.23 |
| 2006-09-29 | Carlos Zambrano | R | 25 | W 2-5 | vs COL | 33 | 146 | L | 7.0 | 3 | 4 | 2 | 0 | 4 | 9 | 128 | 52 | 76 | 59% | 16-7 | 3.41 | 1.29 |
| 2006-09-30 | Juan Mateo | R | 24 | W 9-11 | vs COL | 10 | 10 | - | 1.2 | 4 | 7 | 7 | 2 | 4 | 1 | 62 | 28 | 34 | 55% | 1-3 | 5.28 | 1.61 |
| 2006-10-01 | Wade Miller | R | 30 | L 8-5 | vs COL | 5 | 144 | - | 4.0 | 6 | 4 | 4 | 1 | 3 | 4 | 91 | 38 | 53 | 58% | 0-2 | 4.50 | 1.68 |