| West | W | L | Pct | GB |
| LA Dodgers | 88 | 74 | .543 | -- |
| San Diego | 88 | 74 | .543 | -- |
| SF Giants | 76 | 85 | .472 | 11.5 |
| Arizona | 76 | 86 | .469 | 12.0 |
| Colorado | 76 | 86 | .469 | 12.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2006-04-03 | Derek Lowe | R | 33 | W 10-11 | vs ATL | 1 | 156 | L | 5.0 | 9 | 8 | 7 | 2 | 1 | 2 | 69 | 19 | 50 | 72% | 0-1 | 12.60 | 2.00 |
| 2006-04-04 | Brad Penny | R | 28 | L 5-4 | vs ATL | 1 | 163 | W | 5.0 | 5 | 1 | 1 | 1 | 0 | 8 | 92 | 30 | 62 | 67% | 1-0 | 1.80 | 1.00 |
| 2006-04-05 | Odalis Perez | L | 28 | W 8-9 | vs ATL | 1 | 146 | - | 3.0 | 9 | 7 | 7 | 1 | 0 | 3 | 52 | 17 | 35 | 67% | 0-0 | 21.00 | 3.00 |
| 2006-04-07 | Brett Tomko | R | 33 | W 5-3 | @ PHI | 1 | 217 | W | 6.0 | 8 | 3 | 3 | 2 | 1 | 4 | 94 | 34 | 60 | 64% | 1-0 | 4.50 | 1.50 |
| 2006-04-09 | Derek Lowe | R | 33 | L 3-6 | @ PHI | 2 | 157 | - | 6.0 | 4 | 2 | 2 | 0 | 3 | 0 | 82 | 37 | 45 | 55% | 0-1 | 7.36 | 1.55 |
| 2006-04-09 | Brad Penny | R | 28 | W 6-2 | @ PHI | 2 | 164 | W | 7.0 | 4 | 1 | 1 | 0 | 1 | 6 | 111 | 42 | 69 | 62% | 2-0 | 1.50 | 0.83 |
| 2006-04-10 | Odalis Perez | L | 28 | W 8-3 | @ PIT | 2 | 147 | W | 5.1 | 6 | 1 | 1 | 0 | 2 | 3 | 85 | 28 | 57 | 67% | 1-0 | 9.00 | 2.13 |
| 2006-04-11 | Jae-Wong Seo | R | 29 | L 6-7 | @ PIT | 1 | 67 | - | 5.0 | 7 | 5 | 5 | 3 | 1 | 4 | 89 | 30 | 59 | 66% | 0-0 | 9.00 | 1.38 |
| 2006-04-12 | Brett Tomko | R | 33 | L 5-9 | @ PIT | 2 | 218 | - | 5.0 | 9 | 5 | 5 | 3 | 1 | 4 | 91 | 32 | 59 | 65% | 1-0 | 6.55 | 1.73 |
| 2006-04-13 | Derek Lowe | R | 33 | W 13-5 | @ PIT | 3 | 158 | W | 6.0 | 6 | 4 | 2 | 1 | 3 | 5 | 111 | 41 | 70 | 63% | 1-1 | 5.82 | 1.53 |
| 2006-04-14 | Brad Penny | R | 28 | W 1-2 | vs SFN | 3 | 165 | - | 6.0 | 2 | 1 | 1 | 1 | 0 | 4 | 77 | 27 | 50 | 65% | 2-0 | 1.50 | 0.67 |
| 2006-04-15 | Odalis Perez | L | 28 | L 3-1 | vs SFN | 3 | 148 | W | 7.0 | 3 | 1 | 1 | 0 | 3 | 2 | 94 | 37 | 57 | 61% | 2-0 | 5.40 | 1.53 |
| 2006-04-16 | Jae-Wong Seo | R | 29 | W 0-2 | vs SFN | 2 | 68 | L | 6.0 | 6 | 2 | 2 | 0 | 1 | 3 | 85 | 31 | 54 | 64% | 0-1 | 6.43 | 1.29 |
| 2006-04-17 | Brett Tomko | R | 33 | W 1-4 | vs CHN | 3 | 219 | L | 6.0 | 7 | 4 | 3 | 1 | 1 | 2 | 88 | 30 | 58 | 66% | 1-1 | 5.82 | 1.59 |
| 2006-04-18 | Derek Lowe | R | 33 | L 2-1 | vs CHN | 4 | 159 | - | 7.0 | 5 | 1 | 1 | 0 | 1 | 6 | 100 | 34 | 66 | 66% | 1-1 | 4.50 | 1.33 |
| 2006-04-19 | Brad Penny | R | 28 | W 4-5 | vs CHN | 4 | 166 | - | 6.0 | 9 | 2 | 2 | 0 | 1 | 7 | 95 | 34 | 61 | 64% | 2-0 | 1.88 | 0.92 |
| 2006-04-21 | Odalis Perez | L | 28 | L 6-3 | vs ARI | 4 | 149 | W | 6.0 | 4 | 1 | 1 | 0 | 1 | 4 | 102 | 40 | 62 | 61% | 3-0 | 4.29 | 1.33 |
| 2006-04-22 | Jae-Wong Seo | R | 29 | W 4-5 | vs ARI | 3 | 69 | L | 3.2 | 9 | 5 | 5 | 1 | 1 | 2 | 77 | 27 | 50 | 65% | 0-2 | 7.50 | 1.56 |
| 2006-04-23 | Brett Tomko | R | 33 | L 6-4 | vs ARI | 4 | 220 | W | 6.0 | 4 | 2 | 1 | 0 | 3 | 4 | 114 | 45 | 69 | 61% | 2-1 | 4.70 | 1.48 |
| 2006-04-24 | Derek Lowe | R | 33 | W 6-2 | @ HOU | 5 | 160 | - | 7.0 | 4 | 1 | 1 | 0 | 2 | 4 | 104 | 42 | 62 | 60% | 1-1 | 3.77 | 1.23 |
| 2006-04-25 | Brad Penny | R | 28 | L 3-4 | @ HOU | 5 | 167 | - | 7.0 | 5 | 3 | 3 | 0 | 3 | 1 | 105 | 39 | 66 | 63% | 2-0 | 2.32 | 0.97 |
| 2006-04-26 | Odalis Perez | L | 28 | L 5-8 | @ HOU | 5 | 150 | L | 4.1 | 11 | 7 | 6 | 1 | 1 | 3 | 94 | 31 | 63 | 67% | 3-1 | 5.54 | 1.54 |
| 2006-04-28 | Jae-Wong Seo | R | 29 | W 3-0 | @ SDN | 4 | 70 | W | 6.0 | 2 | 0 | 0 | 0 | 4 | 4 | 93 | 37 | 56 | 60% | 1-2 | 5.63 | 1.42 |
| 2006-04-29 | Brett Tomko | R | 33 | W 4-2 | @ SDN | 5 | 221 | W | 7.0 | 5 | 2 | 2 | 0 | 0 | 2 | 94 | 35 | 59 | 63% | 3-1 | 4.20 | 1.30 |
| 2006-04-30 | Derek Lowe | R | 33 | L 5-6 | @ SDN | 6 | 161 | - | 6.0 | 2 | 0 | 0 | 0 | 3 | 3 | 87 | 37 | 50 | 57% | 1-1 | 3.16 | 1.16 |
| 2006-05-01 | Brad Penny | R | 28 | L 2-3 | @ ARI | 6 | 168 | L | 6.0 | 8 | 3 | 3 | 0 | 2 | 0 | 96 | 42 | 54 | 56% | 2-1 | 2.68 | 1.08 |
| 2006-05-02 | Odalis Perez | L | 28 | L 8-10 | @ ARI | 6 | 151 | - | 4.1 | 8 | 7 | 7 | 2 | 3 | 2 | 71 | 25 | 46 | 65% | 3-1 | 6.90 | 1.70 |
| 2006-05-03 | Jae-Wong Seo | R | 29 | W 5-11 | vs SDN | 5 | 71 | - | 6.0 | 5 | 1 | 1 | 0 | 3 | 4 | 101 | 38 | 63 | 62% | 1-2 | 4.80 | 1.40 |
| 2006-05-04 | Brett Tomko | R | 33 | W 0-3 | vs SDN | 6 | 222 | - | 7.0 | 5 | 0 | 0 | 0 | 2 | 9 | 123 | 48 | 75 | 61% | 3-1 | 3.41 | 1.24 |
| 2006-05-05 | Derek Lowe | R | 33 | L 4-3 | vs MIL | 7 | 162 | - | 7.1 | 7 | 2 | 2 | 1 | 1 | 6 | 101 | 34 | 67 | 66% | 1-1 | 3.07 | 1.16 |
| 2006-05-06 | Brad Penny | R | 28 | L 5-4 | vs MIL | 7 | 169 | - | 5.1 | 7 | 3 | 3 | 0 | 6 | 4 | 114 | 49 | 65 | 57% | 2-1 | 3.00 | 1.26 |
| 2006-05-07 | Aaron Sele | R | 36 | L 10-2 | vs MIL | 1 | 338 | W | 6.2 | 5 | 1 | 1 | 0 | 1 | 2 | 94 | 38 | 56 | 60% | 1-0 | 1.29 | 0.86 |
| 2006-05-09 | Jae-Wong Seo | R | 29 | L 12-7 | vs HOU | 6 | 72 | - | 3.1 | 8 | 6 | 6 | 3 | 1 | 3 | 60 | 20 | 40 | 67% | 1-2 | 6.00 | 1.55 |
| 2006-05-10 | Brett Tomko | R | 33 | L 9-6 | vs HOU | 7 | 223 | W | 6.0 | 1 | 0 | 0 | 0 | 3 | 3 | 102 | 44 | 58 | 57% | 4-1 | 2.93 | 1.16 |
| 2006-05-11 | Derek Lowe | R | 33 | W 2-4 | vs HOU | 8 | 163 | L | 7.0 | 6 | 4 | 2 | 0 | 1 | 0 | 93 | 32 | 61 | 66% | 1-2 | 3.00 | 1.14 |
| 2006-05-12 | Brad Penny | R | 28 | W 6-1 | @ SFN | 8 | 170 | W | 5.0 | 2 | 0 | 0 | 0 | 3 | 3 | 87 | 38 | 49 | 56% | 3-1 | 2.68 | 1.23 |
| 2006-05-13 | Aaron Sele | R | 36 | L 5-6 | @ SFN | 2 | 339 | - | 7.0 | 5 | 2 | 2 | 0 | 2 | 3 | 86 | 35 | 51 | 59% | 1-0 | 1.93 | 0.93 |
| 2006-05-14 | Jae-Wong Seo | R | 29 | W 6-3 | @ SFN | 7 | 73 | - | 6.0 | 3 | 1 | 1 | 0 | 2 | 2 | 84 | 35 | 49 | 58% | 1-2 | 5.31 | 1.44 |
| 2006-05-15 | Brett Tomko | R | 33 | W 5-4 | @ COL | 8 | 224 | W | 7.0 | 5 | 3 | 2 | 1 | 1 | 3 | 100 | 35 | 65 | 65% | 5-1 | 2.88 | 1.12 |
| 2006-05-16 | Derek Lowe | R | 33 | L 1-5 | @ COL | 9 | 164 | L | 6.0 | 9 | 5 | 5 | 1 | 0 | 0 | 76 | 20 | 56 | 74% | 1-3 | 3.47 | 1.18 |
| 2006-05-17 | Brad Penny | R | 28 | W 3-2 | @ COL | 9 | 171 | W | 6.0 | 6 | 1 | 1 | 0 | 0 | 7 | 108 | 34 | 74 | 69% | 4-1 | 2.55 | 1.21 |
| 2006-05-19 | Aaron Sele | R | 36 | L 16-3 | vs ANA | 3 | 340 | W | 6.0 | 6 | 2 | 2 | 1 | 1 | 3 | 80 | 32 | 48 | 60% | 2-0 | 2.25 | 1.00 |
| 2006-05-20 | Brett Tomko | R | 33 | L 8-4 | vs ANA | 9 | 225 | - | 6.0 | 10 | 4 | 4 | 1 | 0 | 4 | 106 | 30 | 76 | 72% | 5-1 | 3.21 | 1.18 |
| 2006-05-21 | Derek Lowe | R | 33 | L 7-0 | vs ANA | 10 | 165 | W | 7.0 | 3 | 0 | 0 | 0 | 3 | 7 | 116 | 45 | 71 | 61% | 2-3 | 3.09 | 1.14 |
| 2006-05-22 | Jae-Wong Seo | R | 29 | L 6-1 | vs COL | 8 | 74 | W | 7.0 | 6 | 1 | 0 | 0 | 1 | 2 | 84 | 25 | 59 | 70% | 2-2 | 4.50 | 1.37 |
| 2006-05-23 | Brad Penny | R | 28 | L 8-1 | vs COL | 10 | 172 | W | 5.0 | 4 | 0 | 0 | 0 | 1 | 5 | 102 | 40 | 62 | 61% | 5-1 | 2.33 | 1.19 |
| 2006-05-24 | Aaron Sele | R | 36 | L 7-1 | vs COL | 4 | 341 | W | 7.0 | 3 | 0 | 0 | 0 | 1 | 5 | 89 | 32 | 57 | 64% | 3-0 | 1.67 | 0.89 |
| 2006-05-26 | Brett Tomko | R | 33 | L 4-10 | @ WAS | 10 | 226 | L | 4.2 | 9 | 6 | 6 | 0 | 2 | 5 | 105 | 41 | 64 | 61% | 5-2 | 3.84 | 1.26 |
| 2006-05-27 | Derek Lowe | R | 33 | W 3-1 | @ WAS | 11 | 166 | W | 7.0 | 5 | 1 | 1 | 0 | 1 | 3 | 99 | 31 | 68 | 69% | 3-3 | 2.92 | 1.11 |
| 2006-05-28 | Jae-Wong Seo | R | 29 | L 4-10 | @ WAS | 9 | 75 | L | 2.2 | 7 | 6 | 6 | 1 | 3 | 3 | 62 | 25 | 37 | 60% | 2-3 | 5.33 | 1.49 |
| 2006-05-29 | Brad Penny | R | 28 | W 12-5 | @ ATL | 11 | 173 | - | 4.1 | 9 | 5 | 5 | 0 | 0 | 1 | 70 | 25 | 45 | 64% | 5-1 | 2.86 | 1.24 |
| 2006-05-30 | Aaron Sele | R | 36 | W 8-3 | @ ATL | 5 | 342 | - | 6.0 | 7 | 3 | 3 | 1 | 3 | 3 | 112 | 46 | 66 | 59% | 3-0 | 2.18 | 1.03 |
| 2006-05-31 | Brett Tomko | R | 33 | L 3-9 | @ ATL | 11 | 227 | L | 3.0 | 6 | 7 | 5 | 2 | 2 | 4 | 71 | 32 | 39 | 55% | 5-3 | 4.36 | 1.33 |
| 2006-06-01 | Derek Lowe | R | 33 | L 7-2 | vs PHI | 12 | 167 | W | 6.0 | 5 | 0 | 0 | 0 | 2 | 3 | 99 | 41 | 58 | 59% | 4-3 | 2.69 | 1.12 |
| 2006-06-02 | Jae-Wong Seo | R | 29 | W 6-8 | vs PHI | 10 | 76 | - | 4.0 | 5 | 3 | 3 | 2 | 1 | 4 | 79 | 32 | 47 | 59% | 2-3 | 5.43 | 1.49 |
| 2006-06-03 | Brad Penny | R | 28 | L 8-2 | vs PHI | 12 | 174 | W | 6.0 | 1 | 0 | 0 | 0 | 4 | 7 | 109 | 42 | 67 | 61% | 6-1 | 2.61 | 1.20 |
| 2006-06-04 | Aaron Sele | R | 36 | W 4-6 | vs PHI | 6 | 343 | - | 6.0 | 6 | 3 | 2 | 1 | 0 | 6 | 92 | 36 | 56 | 61% | 3-0 | 2.31 | 1.03 |
| 2006-06-05 | Brett Tomko | R | 33 | W 1-4 | vs NYN | 12 | 228 | L | 5.1 | 9 | 4 | 4 | 2 | 1 | 0 | 92 | 31 | 61 | 66% | 5-4 | 4.57 | 1.38 |
| 2006-06-06 | Derek Lowe | R | 33 | L 8-5 | vs NYN | 13 | 168 | W | 6.0 | 5 | 2 | 2 | 0 | 4 | 3 | 107 | 42 | 65 | 61% | 5-3 | 2.71 | 1.14 |
| 2006-06-07 | Odalis Perez | L | 28 | W 7-9 | vs NYN | 7 | 152 | L | 3.2 | 11 | 7 | 7 | 0 | 1 | 4 | 68 | 16 | 52 | 76% | 4-2 | 7.07 | 1.83 |
| 2006-06-09 | Brad Penny | R | 28 | W 3-0 | @ COL | 13 | 175 | W | 8.1 | 5 | 0 | 0 | 0 | 2 | 5 | 120 | 34 | 86 | 72% | 7-1 | 2.34 | 1.17 |
| 2006-06-10 | Brett Tomko | R | 33 | L 9-12 | @ COL | 13 | 229 | L | 3.2 | 6 | 7 | 7 | 1 | 2 | 2 | 73 | 28 | 45 | 62% | 5-5 | 5.18 | 1.41 |
| 2006-06-11 | Derek Lowe | R | 33 | W 6-5 | @ COL | 14 | 169 | - | 5.2 | 8 | 3 | 3 | 0 | 2 | 3 | 98 | 32 | 66 | 67% | 5-3 | 2.83 | 1.18 |
| 2006-06-13 | Aaron Sele | R | 36 | L 1-9 | @ SDN | 7 | 344 | L | 4.0 | 6 | 5 | 1 | 0 | 5 | 0 | 89 | 39 | 50 | 56% | 3-1 | 2.30 | 1.19 |
| 2006-06-14 | Brad Penny | R | 28 | L 3-5 | @ SDN | 14 | 176 | - | 6.0 | 5 | 3 | 3 | 1 | 1 | 5 | 113 | 40 | 73 | 65% | 7-1 | 2.49 | 1.16 |
| 2006-06-15 | Chad Billingsley | R | 22 | W 7-3 | @ SDN | 1 | 1 | - | 5.1 | 6 | 2 | 2 | 0 | 2 | 3 | 100 | 39 | 61 | 61% | 0-0 | 3.60 | 1.60 |
| 2006-06-16 | Brett Tomko | R | 33 | L 3-7 | @ OAK | 14 | 230 | L | 5.0 | 9 | 5 | 5 | 1 | 1 | 0 | 97 | 33 | 64 | 66% | 5-6 | 5.42 | 1.45 |
| 2006-06-17 | Derek Lowe | R | 33 | L 4-5 | @ OAK | 15 | 170 | - | 7.2 | 5 | 4 | 4 | 0 | 5 | 3 | 103 | 41 | 62 | 60% | 5-3 | 2.97 | 1.19 |
| 2006-06-18 | Aaron Sele | R | 36 | L 2-5 | @ OAK | 8 | 345 | L | 4.0 | 7 | 5 | 5 | 0 | 3 | 0 | 75 | 37 | 38 | 51% | 3-2 | 3.06 | 1.30 |
| 2006-06-20 | Brad Penny | R | 28 | W 4-9 | vs SEA | 15 | 177 | L | 6.0 | 10 | 5 | 5 | 2 | 0 | 2 | 78 | 25 | 53 | 68% | 7-2 | 2.83 | 1.19 |
| 2006-06-21 | Chad Billingsley | R | 22 | W 5-8 | vs SEA | 2 | 2 | - | 5.0 | 5 | 2 | 2 | 1 | 4 | 1 | 97 | 39 | 58 | 60% | 0-0 | 3.60 | 1.70 |
| 2006-06-22 | Derek Lowe | R | 33 | L 4-2 | vs SEA | 16 | 171 | W | 9.0 | 7 | 2 | 2 | 2 | 0 | 6 | 116 | 43 | 73 | 63% | 6-3 | 2.89 | 1.15 |
| 2006-06-23 | Brett Tomko | R | 33 | L 10-4 | vs PIT | 15 | 231 | W | 5.0 | 2 | 0 | 0 | 0 | 0 | 1 | 68 | 24 | 44 | 65% | 6-6 | 5.10 | 1.39 |
| 2006-06-24 | Aaron Sele | R | 36 | L 7-0 | vs PIT | 9 | 346 | W | 6.0 | 5 | 0 | 0 | 0 | 1 | 4 | 88 | 31 | 57 | 65% | 4-2 | 2.72 | 1.26 |
| 2006-06-25 | Brad Penny | R | 28 | L 7-4 | vs PIT | 16 | 178 | W | 5.0 | 6 | 4 | 4 | 1 | 2 | 5 | 90 | 33 | 57 | 63% | 8-2 | 3.06 | 1.21 |
| 2006-06-26 | Chad Billingsley | R | 22 | L 2-8 | @ MIN | 3 | 3 | L | 5.2 | 7 | 6 | 6 | 0 | 7 | 2 | 103 | 48 | 55 | 53% | 0-1 | 5.63 | 1.94 |
| 2006-06-27 | Derek Lowe | R | 33 | L 2-9 | @ MIN | 17 | 172 | L | 5.1 | 12 | 9 | 9 | 0 | 2 | 3 | 100 | 39 | 61 | 61% | 6-4 | 3.49 | 1.23 |
| 2006-06-28 | Odalis Perez | L | 28 | L 3-6 | @ MIN | 8 | 153 | L | 4.1 | 11 | 6 | 6 | 1 | 0 | 0 | 75 | 26 | 49 | 65% | 4-3 | 6.79 | 1.81 |
| 2006-06-30 | Brad Penny | R | 28 | W 6-1 | @ ANA | 17 | 179 | W | 7.0 | 7 | 1 | 1 | 0 | 0 | 6 | 104 | 28 | 76 | 73% | 9-2 | 2.94 | 1.20 |
| 2006-07-01 | Mark Hendrickson | L | 32 | L 2-9 | @ ANA | 14 | 109 | L | 5.0 | 7 | 5 | 1 | 1 | 2 | 2 | 82 | 28 | 54 | 66% | 4-9 | 3.69 | 1.31 |
| 2006-07-02 | Chad Billingsley | R | 22 | L 0-4 | @ ANA | 4 | 4 | L | 6.0 | 4 | 4 | 2 | 1 | 4 | 3 | 91 | 38 | 53 | 58% | 0-2 | 4.91 | 1.77 |
| 2006-07-03 | Derek Lowe | R | 33 | L 10-4 | vs ARI | 18 | 173 | W | 5.0 | 7 | 2 | 2 | 0 | 2 | 2 | 93 | 35 | 58 | 62% | 7-4 | 3.49 | 1.25 |
| 2006-07-04 | Aaron Sele | R | 36 | L 11-3 | vs ARI | 10 | 347 | W | 6.0 | 7 | 2 | 2 | 1 | 1 | 5 | 101 | 38 | 63 | 62% | 5-2 | 3.05 | 1.32 |
| 2006-07-05 | Brad Penny | R | 28 | L 5-4 | vs ARI | 18 | 180 | W | 7.0 | 7 | 2 | 2 | 1 | 1 | 6 | 105 | 37 | 68 | 65% | 10-2 | 2.92 | 1.19 |
| 2006-07-06 | Mark Hendrickson | L | 32 | W 4-5 | vs SFN | 15 | 110 | L | 6.0 | 9 | 5 | 5 | 0 | 1 | 3 | 88 | 23 | 65 | 74% | 4-10 | 3.92 | 1.33 |
| 2006-07-07 | Chad Billingsley | R | 22 | L 9-7 | vs SFN | 5 | 5 | - | 5.1 | 6 | 5 | 4 | 2 | 4 | 5 | 96 | 46 | 50 | 52% | 0-2 | 5.33 | 1.81 |
| 2006-07-08 | Derek Lowe | R | 33 | W 7-11 | vs SFN | 19 | 174 | L | 4.2 | 8 | 7 | 7 | 2 | 3 | 2 | 102 | 39 | 63 | 62% | 7-5 | 3.87 | 1.29 |
| 2006-07-09 | Aaron Sele | R | 36 | L 3-1 | vs SFN | 11 | 348 | W | 6.0 | 4 | 1 | 1 | 0 | 2 | 7 | 97 | 32 | 65 | 67% | 6-2 | 2.91 | 1.29 |
| 2006-07-13 | Chad Billingsley | R | 22 | L 2-3 | @ SLN | 6 | 6 | - | 5.0 | 6 | 0 | 0 | 0 | 5 | 4 | 101 | 48 | 53 | 52% | 0-2 | 4.50 | 1.88 |
| 2006-07-14 | Derek Lowe | R | 33 | L 0-5 | @ SLN | 20 | 175 | L | 6.0 | 11 | 4 | 4 | 1 | 1 | 5 | 101 | 42 | 59 | 58% | 7-6 | 3.97 | 1.32 |
| 2006-07-15 | Mark Hendrickson | L | 32 | L 1-2 | @ SLN | 16 | 111 | - | 6.2 | 5 | 1 | 1 | 1 | 2 | 4 | 109 | 46 | 63 | 58% | 4-10 | 3.79 | 1.32 |
| 2006-07-16 | Brad Penny | R | 28 | L 3-11 | @ SLN | 19 | 181 | L | 5.0 | 10 | 6 | 6 | 0 | 1 | 5 | 99 | 36 | 63 | 64% | 10-3 | 3.27 | 1.26 |
| 2006-07-17 | Aaron Sele | R | 36 | L 3-8 | @ ARI | 12 | 349 | L | 5.0 | 9 | 5 | 5 | 0 | 1 | 4 | 106 | 41 | 65 | 61% | 6-3 | 3.34 | 1.34 |
| 2006-07-18 | Chad Billingsley | R | 22 | W 4-1 | @ ARI | 7 | 7 | W | 7.0 | 6 | 0 | 0 | 0 | 2 | 4 | 104 | 41 | 63 | 61% | 1-2 | 3.69 | 1.74 |
| 2006-07-19 | Derek Lowe | R | 33 | L 0-8 | @ ARI | 21 | 176 | L | 4.1 | 11 | 5 | 5 | 1 | 0 | 2 | 76 | 24 | 52 | 68% | 7-7 | 4.19 | 1.37 |
| 2006-07-20 | Mark Hendrickson | L | 32 | L 2-5 | @ ARI | 17 | 112 | L | 5.1 | 9 | 5 | 5 | 1 | 2 | 2 | 105 | 39 | 66 | 63% | 4-11 | 3.98 | 1.35 |
| 2006-07-21 | Brad Penny | R | 28 | W 0-2 | vs SLN | 20 | 182 | L | 6.2 | 6 | 2 | 2 | 1 | 3 | 2 | 101 | 41 | 60 | 59% | 10-4 | 3.23 | 1.26 |
| 2006-07-22 | Aaron Sele | R | 36 | W 1-6 | vs SLN | 13 | 350 | L | 4.0 | 6 | 5 | 5 | 2 | 2 | 0 | 82 | 33 | 49 | 60% | 6-4 | 3.77 | 1.38 |
| 2006-07-23 | Chad Billingsley | R | 22 | W 1-6 | vs SLN | 8 | 8 | L | 5.0 | 6 | 6 | 5 | 2 | 5 | 1 | 98 | 45 | 53 | 54% | 1-3 | 4.30 | 1.80 |
| 2006-07-24 | Derek Lowe | R | 33 | W 6-7 | vs SDN | 22 | 177 | - | 6.2 | 7 | 5 | 3 | 0 | 1 | 6 | 99 | 33 | 66 | 67% | 7-7 | 4.17 | 1.36 |
| 2006-07-25 | Mark Hendrickson | L | 32 | W 3-7 | vs SDN | 18 | 113 | L | 6.0 | 8 | 4 | 4 | 1 | 1 | 3 | 90 | 35 | 55 | 61% | 4-12 | 4.08 | 1.35 |
| 2006-07-26 | Brad Penny | R | 28 | W 3-10 | vs SDN | 21 | 183 | L | 5.0 | 9 | 6 | 6 | 1 | 1 | 3 | 73 | 26 | 47 | 64% | 10-5 | 3.53 | 1.29 |
| 2006-07-28 | Chad Billingsley | R | 22 | L 13-1 | vs WAS | 9 | 9 | W | 6.0 | 4 | 1 | 1 | 0 | 5 | 5 | 110 | 52 | 58 | 53% | 2-3 | 3.96 | 1.76 |
| 2006-07-29 | Derek Lowe | R | 33 | L 7-5 | vs WAS | 23 | 178 | W | 5.0 | 7 | 4 | 4 | 1 | 1 | 8 | 102 | 32 | 70 | 69% | 8-7 | 4.28 | 1.36 |
| 2006-07-30 | Mark Hendrickson | L | 32 | L 4-3 | vs WAS | 19 | 114 | - | 6.0 | 6 | 3 | 3 | 0 | 7 | 3 | 107 | 47 | 60 | 56% | 4-12 | 4.10 | 1.39 |
| 2006-08-01 | Aaron Sele | R | 36 | W 10-4 | @ CIN | 14 | 351 | W | 6.0 | 8 | 4 | 4 | 2 | 0 | 2 | 85 | 31 | 54 | 64% | 7-4 | 3.95 | 1.38 |
| 2006-08-02 | Brad Penny | R | 28 | W 5-3 | @ CIN | 22 | 184 | W | 6.0 | 3 | 2 | 2 | 2 | 2 | 6 | 103 | 34 | 69 | 67% | 11-5 | 3.50 | 1.27 |
| 2006-08-03 | Greg Maddux | R | 40 | W 3-0 | @ CIN | 23 | 662 | W | 6.0 | 0 | 0 | 0 | 0 | 3 | 3 | 72 | 31 | 41 | 57% | 10-11 | 4.50 | 1.26 |
| 2006-08-04 | Derek Lowe | R | 33 | W 6-2 | @ FLO | 24 | 179 | W | 7.0 | 5 | 1 | 1 | 0 | 0 | 5 | 92 | 34 | 58 | 63% | 9-7 | 4.14 | 1.33 |
| 2006-08-05 | Chad Billingsley | R | 22 | W 10-2 | @ FLO | 10 | 10 | W | 6.0 | 3 | 1 | 1 | 0 | 3 | 7 | 107 | 42 | 65 | 61% | 3-3 | 3.70 | 1.68 |
| 2006-08-06 | Mark Hendrickson | L | 32 | W 7-3 | @ FLO | 20 | 115 | W | 6.0 | 6 | 3 | 3 | 0 | 2 | 4 | 101 | 38 | 63 | 62% | 5-12 | 4.12 | 1.39 |
| 2006-08-07 | Brad Penny | R | 28 | L 7-2 | vs COL | 23 | 185 | W | 8.0 | 5 | 2 | 2 | 2 | 0 | 4 | 105 | 33 | 72 | 69% | 12-5 | 3.43 | 1.23 |
| 2006-08-08 | Greg Maddux | R | 40 | L 4-2 | vs COL | 24 | 663 | - | 6.0 | 7 | 2 | 2 | 0 | 1 | 2 | 79 | 26 | 53 | 67% | 10-11 | 4.44 | 1.26 |
| 2006-08-09 | Derek Lowe | R | 33 | W 1-3 | vs COL | 25 | 180 | L | 8.2 | 6 | 3 | 3 | 1 | 0 | 6 | 107 | 36 | 71 | 66% | 9-8 | 4.10 | 1.30 |
| 2006-08-10 | Chad Billingsley | R | 22 | L 4-3 | vs COL | 11 | 11 | - | 5.0 | 3 | 1 | 1 | 1 | 6 | 3 | 96 | 47 | 49 | 51% | 3-3 | 3.54 | 1.69 |
| 2006-08-11 | Mark Hendrickson | L | 32 | L 3-2 | vs SFN | 21 | 116 | - | 7.0 | 10 | 2 | 2 | 0 | 4 | 3 | 108 | 47 | 61 | 56% | 5-12 | 4.04 | 1.42 |
| 2006-08-12 | Brad Penny | R | 28 | L 6-5 | vs SFN | 24 | 186 | W | 6.0 | 7 | 4 | 3 | 0 | 0 | 7 | 103 | 37 | 66 | 64% | 13-5 | 3.48 | 1.23 |
| 2006-08-13 | Greg Maddux | R | 40 | L 1-0 | vs SFN | 25 | 664 | - | 8.0 | 2 | 0 | 0 | 0 | 0 | 4 | 68 | 18 | 50 | 74% | 10-11 | 4.21 | 1.21 |
| 2006-08-14 | Derek Lowe | R | 33 | L 4-2 | vs FLO | 26 | 181 | W | 7.0 | 4 | 1 | 1 | 0 | 2 | 2 | 106 | 43 | 63 | 59% | 10-8 | 3.98 | 1.28 |
| 2006-08-15 | Chad Billingsley | R | 22 | L 4-0 | vs FLO | 12 | 12 | W | 7.0 | 3 | 0 | 0 | 0 | 1 | 9 | 105 | 38 | 67 | 64% | 4-3 | 3.18 | 1.57 |
| 2006-08-16 | Mark Hendrickson | L | 32 | W 4-15 | vs FLO | 22 | 117 | L | 2.1 | 5 | 5 | 5 | 0 | 3 | 1 | 47 | 18 | 29 | 62% | 5-13 | 4.31 | 1.46 |
| 2006-08-18 | Brad Penny | R | 28 | L 3-7 | @ SFN | 25 | 187 | L | 6.0 | 6 | 6 | 6 | 2 | 3 | 3 | 106 | 47 | 59 | 56% | 13-6 | 3.70 | 1.24 |
| 2006-08-19 | Greg Maddux | R | 40 | W 14-7 | @ SFN | 26 | 665 | W | 6.0 | 6 | 6 | 4 | 1 | 0 | 6 | 80 | 23 | 57 | 71% | 11-11 | 4.28 | 1.20 |
| 2006-08-20 | Derek Lowe | R | 33 | W 5-2 | @ SFN | 27 | 182 | W | 8.0 | 5 | 2 | 1 | 0 | 1 | 6 | 105 | 37 | 68 | 65% | 11-8 | 3.85 | 1.26 |
| 2006-08-21 | Chad Billingsley | R | 22 | L 2-4 | @ SDN | 13 | 13 | - | 5.0 | 6 | 2 | 1 | 0 | 1 | 5 | 101 | 42 | 59 | 58% | 4-3 | 3.08 | 1.56 |
| 2006-08-22 | Mark Hendrickson | L | 32 | L 0-1 | @ SDN | 23 | 118 | L | 6.0 | 5 | 1 | 1 | 0 | 0 | 4 | 90 | 33 | 57 | 63% | 5-14 | 4.19 | 1.43 |
| 2006-08-23 | Brad Penny | R | 28 | L 2-7 | @ SDN | 26 | 188 | L | 4.0 | 7 | 6 | 6 | 0 | 4 | 5 | 105 | 45 | 60 | 57% | 13-7 | 3.95 | 1.28 |
| 2006-08-25 | Greg Maddux | R | 40 | L 7-9 | @ ARI | 27 | 666 | - | 5.0 | 10 | 4 | 2 | 0 | 2 | 0 | 78 | 32 | 46 | 59% | 11-11 | 4.26 | 1.24 |
| 2006-08-26 | Derek Lowe | R | 33 | W 4-3 | @ ARI | 28 | 183 | - | 3.2 | 5 | 1 | 1 | 0 | 0 | 0 | 50 | 16 | 34 | 68% | 11-8 | 3.81 | 1.26 |
| 2006-08-27 | Chad Billingsley | R | 22 | W 6-3 | @ ARI | 14 | 14 | W | 7.0 | 9 | 2 | 2 | 0 | 1 | 1 | 92 | 36 | 56 | 61% | 5-3 | 3.04 | 1.55 |
| 2006-08-28 | Brad Penny | R | 28 | L 6-5 | vs CIN | 27 | 189 | W | 5.0 | 4 | 1 | 1 | 0 | 5 | 3 | 103 | 41 | 62 | 60% | 14-7 | 3.88 | 1.29 |
| 2006-08-29 | Mark Hendrickson | L | 32 | L 6-5 | vs CIN | 24 | 119 | - | 4.0 | 9 | 4 | 4 | 2 | 0 | 3 | 76 | 23 | 53 | 70% | 5-14 | 4.32 | 1.45 |
| 2006-08-30 | Greg Maddux | R | 40 | L 7-3 | vs CIN | 28 | 667 | W | 7.0 | 8 | 2 | 2 | 1 | 0 | 3 | 77 | 23 | 54 | 70% | 12-11 | 4.19 | 1.24 |
| 2006-09-01 | Derek Lowe | R | 33 | L 6-3 | vs COL | 29 | 184 | W | 5.0 | 7 | 3 | 3 | 0 | 3 | 1 | 82 | 38 | 44 | 54% | 13-8 | 3.79 | 1.26 |
| 2006-09-02 | Brad Penny | R | 28 | L 14-5 | vs COL | 28 | 190 | W | 5.1 | 9 | 5 | 4 | 0 | 0 | 2 | 79 | 23 | 56 | 71% | 15-7 | 3.98 | 1.31 |
| 2006-09-03 | Aaron Sele | R | 36 | W 5-12 | vs COL | 15 | 352 | L | 4.1 | 9 | 6 | 6 | 0 | 0 | 2 | 68 | 24 | 44 | 65% | 7-6 | 4.50 | 1.45 |
| 2006-09-04 | Greg Maddux | R | 40 | L 3-6 | @ MIL | 29 | 668 | L | 5.1 | 10 | 6 | 6 | 0 | 3 | 2 | 95 | 34 | 61 | 64% | 12-12 | 4.35 | 1.27 |
| 2006-09-05 | Mark Hendrickson | L | 32 | L 0-9 | @ MIL | 25 | 120 | L | 4.0 | 7 | 5 | 4 | 1 | 1 | 4 | 83 | 33 | 50 | 60% | 5-15 | 4.41 | 1.46 |
| 2006-09-06 | Derek Lowe | R | 33 | W 2-1 | @ MIL | 30 | 185 | W | 8.0 | 3 | 1 | 0 | 0 | 1 | 1 | 78 | 30 | 48 | 62% | 14-8 | 3.64 | 1.23 |
| 2006-09-07 | Brad Penny | R | 28 | L 0-7 | @ NYN | 29 | 191 | L | 5.2 | 10 | 7 | 7 | 2 | 1 | 4 | 119 | 41 | 78 | 66% | 15-8 | 4.21 | 1.33 |
| 2006-09-08 | Hong-chih Kuo | L | 25 | W 5-0 | @ NYN | 1 | 1 | W | 6.0 | 3 | 0 | 0 | 0 | 3 | 7 | 91 | 35 | 56 | 62% | 1-4 | 4.50 | 1.61 |
| 2006-09-09 | Greg Maddux | R | 40 | L 2-3 | @ NYN | 30 | 669 | L | 5.1 | 5 | 3 | 3 | 1 | 1 | 3 | 71 | 26 | 45 | 63% | 12-13 | 4.38 | 1.26 |
| 2006-09-10 | Eric Stults | L | 27 | W 9-1 | @ NYN | 1 | 1 | W | 6.0 | 2 | 1 | 1 | 1 | 2 | 3 | 86 | 32 | 54 | 63% | 1-0 | 4.00 | 1.11 |
| 2006-09-12 | Derek Lowe | R | 33 | L 8-9 | @ CHN | 31 | 186 | - | 5.0 | 10 | 5 | 5 | 0 | 1 | 2 | 91 | 37 | 54 | 59% | 14-8 | 3.77 | 1.26 |
| 2006-09-13 | Brad Penny | R | 28 | W 6-0 | @ CHN | 30 | 192 | W | 7.0 | 7 | 0 | 0 | 0 | 0 | 6 | 104 | 38 | 66 | 63% | 16-8 | 4.04 | 1.31 |
| 2006-09-14 | Hong-chih Kuo | L | 25 | L 5-6 | @ CHN | 2 | 2 | - | 6.0 | 7 | 2 | 2 | 0 | 0 | 6 | 93 | 28 | 65 | 70% | 1-4 | 4.29 | 1.55 |
| 2006-09-15 | Greg Maddux | R | 40 | L 3-1 | vs SDN | 31 | 670 | W | 7.0 | 1 | 0 | 0 | 0 | 3 | 1 | 68 | 25 | 43 | 63% | 13-13 | 4.22 | 1.24 |
| 2006-09-16 | Chad Billingsley | R | 22 | W 2-11 | vs SDN | 15 | 15 | L | 1.0 | 3 | 3 | 3 | 0 | 2 | 1 | 40 | 22 | 18 | 45% | 5-4 | 3.33 | 1.59 |
| 2006-09-17 | Derek Lowe | R | 33 | W 1-2 | vs SDN | 32 | 187 | - | 7.0 | 7 | 1 | 1 | 1 | 1 | 9 | 114 | 39 | 75 | 66% | 14-8 | 3.69 | 1.25 |
| 2006-09-18 | Brad Penny | R | 28 | L 11-10 | vs SDN | 31 | 193 | - | 5.0 | 7 | 4 | 4 | 0 | 3 | 6 | 105 | 39 | 66 | 63% | 16-8 | 4.13 | 1.33 |
| 2006-09-19 | Hong-chih Kuo | L | 25 | W 6-10 | vs PIT | 3 | 3 | L | 5.1 | 6 | 5 | 5 | 1 | 2 | 8 | 95 | 35 | 60 | 63% | 1-5 | 4.69 | 1.52 |
| 2006-09-20 | Greg Maddux | R | 40 | W 4-6 | vs PIT | 32 | 671 | L | 5.0 | 7 | 3 | 3 | 1 | 1 | 5 | 87 | 26 | 61 | 70% | 13-14 | 4.25 | 1.25 |
| 2006-09-21 | Chad Billingsley | R | 22 | L 5-2 | vs PIT | 16 | 16 | W | 5.0 | 6 | 2 | 2 | 0 | 3 | 4 | 96 | 36 | 60 | 63% | 6-4 | 3.35 | 1.60 |
| 2006-09-22 | Derek Lowe | R | 33 | L 2-0 | vs ARI | 33 | 188 | W | 7.0 | 5 | 0 | 0 | 0 | 3 | 3 | 95 | 41 | 54 | 57% | 15-8 | 3.57 | 1.25 |
| 2006-09-23 | Brad Penny | R | 28 | W 3-9 | vs ARI | 32 | 194 | L | 5.0 | 9 | 5 | 4 | 1 | 1 | 7 | 105 | 40 | 65 | 62% | 16-9 | 4.21 | 1.35 |
| 2006-09-24 | Hong-chih Kuo | L | 25 | L 5-1 | vs ARI | 4 | 4 | - | 7.0 | 4 | 1 | 0 | 0 | 2 | 8 | 100 | 29 | 71 | 71% | 1-5 | 4.09 | 1.44 |
| 2006-09-26 | Greg Maddux | R | 40 | W 11-4 | @ COL | 33 | 672 | W | 6.0 | 7 | 3 | 3 | 1 | 0 | 3 | 76 | 28 | 48 | 63% | 14-14 | 4.26 | 1.25 |
| 2006-09-27 | Derek Lowe | R | 33 | W 6-4 | @ COL | 34 | 189 | W | 6.0 | 10 | 4 | 4 | 0 | 1 | 4 | 91 | 33 | 58 | 64% | 16-8 | 3.63 | 1.27 |
| 2006-09-28 | Brad Penny | R | 28 | W 19-11 | @ COL | 33 | 195 | - | 1.0 | 4 | 3 | 3 | 1 | 2 | 3 | 35 | 15 | 20 | 57% | 16-9 | 4.33 | 1.38 |
| 2006-09-29 | Hong-chih Kuo | L | 25 | W 4-3 | @ SFN | 5 | 5 | - | 5.0 | 8 | 3 | 3 | 0 | 0 | 6 | 80 | 22 | 58 | 73% | 1-5 | 4.20 | 1.45 |
| 2006-09-30 | Greg Maddux | R | 40 | W 4-2 | @ SFN | 34 | 673 | W | 7.0 | 3 | 2 | 2 | 1 | 0 | 4 | 71 | 16 | 55 | 77% | 15-14 | 4.20 | 1.22 |
| 2006-10-01 | Eric Stults | L | 27 | W 4-3 | @ SFN | 2 | 2 | - | 5.0 | 4 | 3 | 2 | 0 | 2 | 1 | 63 | 25 | 38 | 60% | 1-0 | 5.50 | 1.33 |