| Central | W | L | Pct | GB |
| Minnesota | 96 | 66 | .593 | -- |
| Detroit | 95 | 67 | .586 | 1.0 |
| Chi White Sox | 90 | 72 | .556 | 6.0 |
| Cleveland | 78 | 84 | .481 | 18.0 |
| KC Royals | 62 | 100 | .383 | 34.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2006-04-03 | Kenny Rogers | L | 41 | W 3-1 | @ KCA | 1 | 401 | W | 6.0 | 3 | 1 | 1 | 0 | 0 | 5 | 81 | 27 | 54 | 67% | 1-0 | 1.50 | 0.50 |
| 2006-04-05 | Jeremy Bonderman | R | 23 | W 14-3 | @ KCA | 1 | 90 | W | 6.2 | 3 | 1 | 1 | 0 | 0 | 8 | 92 | 28 | 64 | 70% | 1-0 | 1.29 | 0.43 |
| 2006-04-06 | Nate Robertson | R | 29 | W 10-6 | @ TEX | 1 | 73 | W | 5.1 | 8 | 3 | 3 | 1 | 0 | 4 | 77 | 30 | 47 | 61% | 1-0 | 5.40 | 1.60 |
| 2006-04-07 | Mike Maroth | L | 29 | W 5-2 | @ TEX | 1 | 122 | W | 5.1 | 8 | 1 | 1 | 1 | 1 | 0 | 84 | 35 | 49 | 58% | 1-0 | 1.80 | 1.80 |
| 2006-04-08 | Justin Verlander | R | 23 | W 7-0 | @ TEX | 1 | 3 | W | 7.0 | 2 | 0 | 0 | 0 | 2 | 7 | 88 | 31 | 57 | 65% | 1-0 | 0.00 | 0.57 |
| 2006-04-09 | Kenny Rogers | L | 41 | L 3-5 | @ TEX | 2 | 402 | L | 5.1 | 12 | 5 | 5 | 0 | 1 | 5 | 99 | 37 | 62 | 63% | 1-1 | 4.91 | 1.45 |
| 2006-04-10 | Jeremy Bonderman | R | 23 | W 3-5 | vs CHA | 2 | 91 | L | 7.0 | 6 | 4 | 4 | 2 | 2 | 8 | 101 | 36 | 65 | 64% | 1-1 | 3.21 | 0.79 |
| 2006-04-12 | Nate Robertson | R | 29 | W 3-4 | vs CHA | 2 | 74 | L | 7.0 | 5 | 4 | 3 | 1 | 3 | 6 | 101 | 39 | 62 | 61% | 1-1 | 4.50 | 1.33 |
| 2006-04-13 | Justin Verlander | R | 23 | W 9-13 | vs CHA | 2 | 4 | L | 2.2 | 7 | 7 | 7 | 2 | 1 | 0 | 63 | 25 | 38 | 60% | 1-1 | 6.30 | 1.20 |
| 2006-04-14 | Kenny Rogers | L | 41 | L 5-1 | vs CLE | 3 | 403 | W | 8.0 | 7 | 1 | 1 | 0 | 3 | 5 | 110 | 43 | 67 | 61% | 2-1 | 3.32 | 1.37 |
| 2006-04-15 | Jeremy Bonderman | R | 23 | W 2-7 | vs CLE | 3 | 92 | L | 3.2 | 8 | 7 | 7 | 1 | 1 | 4 | 70 | 24 | 46 | 66% | 1-2 | 6.35 | 1.18 |
| 2006-04-16 | Mike Maroth | L | 29 | L 1-0 | vs CLE | 2 | 123 | W | 7.0 | 3 | 0 | 0 | 0 | 2 | 5 | 99 | 39 | 60 | 61% | 2-0 | 0.75 | 1.17 |
| 2006-04-17 | Nate Robertson | R | 29 | W 2-10 | vs CLE | 3 | 75 | L | 2.1 | 8 | 7 | 6 | 1 | 1 | 0 | 49 | 16 | 33 | 67% | 1-2 | 7.20 | 1.67 |
| 2006-04-18 | Justin Verlander | R | 23 | L 3-4 | @ OAK | 3 | 5 | L | 7.0 | 5 | 4 | 3 | 2 | 3 | 7 | 118 | 51 | 67 | 57% | 1-2 | 5.29 | 1.18 |
| 2006-04-19 | Kenny Rogers | L | 41 | W 11-4 | @ OAK | 4 | 404 | W | 7.1 | 3 | 3 | 3 | 1 | 2 | 1 | 108 | 41 | 67 | 62% | 3-1 | 3.33 | 1.15 |
| 2006-04-20 | Jeremy Bonderman | R | 23 | W 4-3 | @ OAK | 4 | 93 | - | 7.0 | 5 | 3 | 3 | 0 | 2 | 1 | 98 | 37 | 61 | 62% | 1-2 | 5.63 | 1.13 |
| 2006-04-21 | Mike Maroth | L | 29 | W 2-1 | @ SEA | 3 | 124 | W | 6.0 | 4 | 0 | 0 | 0 | 3 | 3 | 103 | 48 | 55 | 53% | 3-0 | 0.50 | 1.17 |
| 2006-04-22 | Nate Robertson | R | 29 | W 2-0 | @ SEA | 4 | 76 | W | 7.0 | 2 | 0 | 0 | 0 | 2 | 4 | 88 | 33 | 55 | 63% | 2-2 | 4.91 | 1.32 |
| 2006-04-23 | Justin Verlander | R | 23 | W 6-4 | @ SEA | 4 | 6 | W | 7.0 | 4 | 1 | 1 | 0 | 2 | 3 | 95 | 31 | 64 | 67% | 2-2 | 4.13 | 1.08 |
| 2006-04-24 | Kenny Rogers | L | 41 | L 0-3 | @ ANA | 5 | 405 | L | 7.0 | 4 | 2 | 2 | 1 | 3 | 3 | 97 | 41 | 56 | 58% | 3-2 | 3.18 | 1.12 |
| 2006-04-25 | Jeremy Bonderman | R | 23 | W 5-2 | @ ANA | 5 | 94 | W | 6.0 | 3 | 2 | 2 | 0 | 1 | 6 | 97 | 30 | 67 | 69% | 2-2 | 5.10 | 1.03 |
| 2006-04-26 | Mike Maroth | L | 29 | L 0-4 | @ ANA | 4 | 125 | L | 6.0 | 9 | 4 | 4 | 1 | 3 | 2 | 92 | 38 | 54 | 59% | 3-1 | 1.88 | 1.38 |
| 2006-04-28 | Nate Robertson | R | 29 | L 9-0 | vs MIN | 5 | 77 | W | 7.0 | 5 | 0 | 0 | 0 | 1 | 7 | 99 | 34 | 65 | 66% | 3-2 | 3.72 | 1.21 |
| 2006-04-29 | Justin Verlander | R | 23 | L 18-1 | vs MIN | 5 | 7 | W | 7.0 | 6 | 1 | 1 | 0 | 2 | 4 | 102 | 37 | 65 | 64% | 3-2 | 3.48 | 1.10 |
| 2006-04-30 | Kenny Rogers | L | 41 | L 6-0 | vs MIN | 6 | 406 | W | 8.0 | 2 | 0 | 0 | 0 | 1 | 4 | 90 | 32 | 58 | 64% | 4-2 | 2.57 | 0.98 |
| 2006-05-01 | Jeremy Bonderman | R | 24 | L 3-2 | vs KCA | 6 | 95 | W | 8.0 | 4 | 0 | 0 | 0 | 1 | 9 | 94 | 32 | 62 | 66% | 3-2 | 4.03 | 0.95 |
| 2006-05-02 | Mike Maroth | L | 29 | L 4-1 | vs KCA | 5 | 126 | W | 6.0 | 4 | 1 | 1 | 0 | 1 | 2 | 87 | 35 | 52 | 60% | 4-1 | 1.80 | 1.27 |
| 2006-05-03 | Nate Robertson | R | 29 | L 2-1 | vs ANA | 6 | 78 | - | 7.1 | 4 | 1 | 1 | 0 | 2 | 6 | 85 | 29 | 56 | 66% | 3-2 | 3.25 | 1.14 |
| 2006-05-04 | Justin Verlander | R | 23 | W 2-7 | vs ANA | 6 | 8 | L | 6.0 | 9 | 4 | 3 | 2 | 1 | 2 | 76 | 26 | 50 | 66% | 3-3 | 3.65 | 1.19 |
| 2006-05-05 | Kenny Rogers | L | 41 | W 9-6 | @ MIN | 7 | 407 | W | 5.0 | 8 | 5 | 5 | 1 | 2 | 0 | 86 | 36 | 50 | 58% | 5-2 | 3.26 | 1.09 |
| 2006-05-06 | Jeremy Bonderman | R | 24 | L 6-7 | @ MIN | 7 | 96 | - | 6.2 | 10 | 5 | 5 | 0 | 3 | 3 | 86 | 33 | 53 | 62% | 3-2 | 4.40 | 1.09 |
| 2006-05-07 | Mike Maroth | L | 29 | L 2-4 | @ MIN | 6 | 127 | L | 5.0 | 9 | 4 | 4 | 1 | 3 | 3 | 99 | 43 | 56 | 57% | 4-2 | 2.57 | 1.43 |
| 2006-05-09 | Nate Robertson | R | 29 | L 6-7 | @ BAL | 7 | 79 | - | 5.1 | 6 | 4 | 2 | 2 | 5 | 1 | 104 | 45 | 59 | 57% | 3-2 | 3.29 | 1.27 |
| 2006-05-10 | Justin Verlander | R | 23 | W 6-3 | @ BAL | 7 | 9 | W | 6.1 | 7 | 3 | 3 | 0 | 3 | 4 | 98 | 40 | 58 | 59% | 4-3 | 3.77 | 1.26 |
| 2006-05-12 | Kenny Rogers | L | 42 | W 5-4 | @ CLE | 8 | 408 | W | 6.1 | 8 | 2 | 2 | 1 | 1 | 4 | 104 | 39 | 65 | 63% | 6-2 | 3.23 | 1.13 |
| 2006-05-13 | Jeremy Bonderman | R | 24 | W 3-0 | @ CLE | 8 | 97 | W | 8.0 | 3 | 0 | 0 | 0 | 3 | 8 | 102 | 40 | 62 | 61% | 4-2 | 3.74 | 1.04 |
| 2006-05-14 | Mike Maroth | L | 29 | W 3-2 | @ CLE | 7 | 128 | W | 6.0 | 7 | 1 | 0 | 0 | 1 | 2 | 85 | 32 | 53 | 62% | 5-2 | 2.20 | 1.41 |
| 2006-05-16 | Nate Robertson | R | 29 | L 7-4 | vs MIN | 8 | 80 | W | 5.0 | 7 | 3 | 3 | 0 | 3 | 1 | 75 | 28 | 47 | 63% | 4-2 | 3.52 | 1.35 |
| 2006-05-17 | Justin Verlander | R | 23 | L 2-0 | vs MIN | 8 | 10 | W | 8.0 | 6 | 0 | 0 | 0 | 0 | 0 | 103 | 39 | 64 | 62% | 5-3 | 3.18 | 1.18 |
| 2006-05-18 | Kenny Rogers | L | 42 | L 5-3 | vs MIN | 9 | 409 | W | 5.2 | 5 | 2 | 0 | 0 | 2 | 4 | 82 | 32 | 50 | 61% | 7-2 | 2.90 | 1.14 |
| 2006-05-19 | Jeremy Bonderman | R | 24 | W 4-9 | vs CIN | 9 | 98 | L | 3.0 | 6 | 6 | 7 | 1 | 3 | 3 | 66 | 29 | 37 | 56% | 4-3 | 4.66 | 1.14 |
| 2006-05-20 | Mike Maroth | L | 29 | L 7-6 | vs CIN | 8 | 129 | - | 6.1 | 6 | 3 | 3 | 2 | 1 | 5 | 90 | 39 | 51 | 57% | 5-2 | 2.44 | 1.35 |
| 2006-05-21 | Nate Robertson | R | 29 | L 1-0 | vs CIN | 9 | 81 | - | 7.1 | 3 | 0 | 0 | 0 | 5 | 7 | 116 | 52 | 64 | 55% | 4-2 | 3.00 | 1.30 |
| 2006-05-22 | Justin Verlander | R | 23 | W 8-0 | @ KCA | 9 | 11 | W | 9.0 | 5 | 0 | 0 | 0 | 1 | 7 | 113 | 35 | 78 | 69% | 6-3 | 2.70 | 1.10 |
| 2006-05-23 | Kenny Rogers | L | 42 | W 8-5 | @ KCA | 10 | 410 | - | 6.1 | 10 | 5 | 5 | 4 | 1 | 1 | 88 | 32 | 56 | 64% | 7-2 | 3.32 | 1.20 |
| 2006-05-24 | Jeremy Bonderman | R | 24 | W 6-3 | @ KCA | 10 | 99 | W | 7.0 | 10 | 3 | 3 | 1 | 1 | 3 | 89 | 28 | 61 | 69% | 5-3 | 4.57 | 1.19 |
| 2006-05-25 | Mike Maroth | L | 29 | W 13-8 | @ KCA | 9 | 130 | - | 0.1 | 6 | 6 | 6 | 3 | 0 | 0 | 27 | 9 | 18 | 67% | 5-2 | 3.56 | 1.48 |
| 2006-05-26 | Nate Robertson | R | 29 | L 8-3 | vs CLE | 10 | 82 | W | 6.0 | 7 | 3 | 2 | 1 | 1 | 2 | 91 | 37 | 54 | 59% | 5-2 | 3.00 | 1.30 |
| 2006-05-27 | Justin Verlander | R | 23 | L 3-1 | vs CLE | 10 | 12 | W | 7.0 | 7 | 1 | 1 | 1 | 1 | 5 | 97 | 32 | 65 | 67% | 7-3 | 2.55 | 1.10 |
| 2006-05-28 | Kenny Rogers | L | 42 | W 0-9 | vs CLE | 11 | 411 | L | 4.1 | 6 | 5 | 5 | 1 | 3 | 2 | 89 | 39 | 50 | 56% | 7-3 | 3.78 | 1.26 |
| 2006-05-29 | Jeremy Bonderman | R | 24 | W 0-4 | vs NYA | 11 | 100 | L | 7.1 | 9 | 4 | 4 | 0 | 2 | 5 | 113 | 38 | 75 | 66% | 5-4 | 4.63 | 1.23 |
| 2006-05-30 | Roman Colon | R | 27 | W 6-11 | vs NYA | 1 | 8 | - | 2.1 | 7 | 5 | 5 | 0 | 0 | 2 | 43 | 13 | 30 | 70% | 0-0 | 6.75 | 1.83 |
| 2006-05-31 | Nate Robertson | R | 29 | W 1-6 | vs NYA | 11 | 83 | L | 8.2 | 10 | 6 | 6 | 0 | 2 | 7 | 117 | 42 | 75 | 64% | 5-3 | 3.44 | 1.32 |
| 2006-06-01 | Justin Verlander | R | 23 | L 7-6 | vs NYA | 11 | 13 | - | 5.0 | 7 | 6 | 6 | 1 | 4 | 4 | 94 | 39 | 55 | 59% | 7-3 | 3.13 | 1.18 |
| 2006-06-02 | Kenny Rogers | L | 42 | W 2-3 | vs BOS | 12 | 412 | - | 7.0 | 5 | 1 | 1 | 0 | 1 | 7 | 105 | 38 | 67 | 64% | 7-3 | 3.55 | 1.22 |
| 2006-06-03 | Jeremy Bonderman | R | 24 | L 6-2 | vs BOS | 12 | 101 | W | 7.2 | 4 | 2 | 2 | 0 | 2 | 6 | 99 | 38 | 61 | 62% | 6-4 | 4.38 | 1.18 |
| 2006-06-04 | Zach Miner | R | 24 | W 3-8 | vs BOS | 1 | 1 | L | 4.0 | 7 | 3 | 3 | 2 | 2 | 2 | 87 | 40 | 47 | 54% | 0-1 | 6.75 | 2.25 |
| 2006-06-06 | Nate Robertson | R | 29 | L 3-4 | @ CHA | 12 | 84 | - | 6.1 | 6 | 1 | 1 | 1 | 3 | 4 | 108 | 51 | 57 | 53% | 5-3 | 3.24 | 1.32 |
| 2006-06-07 | Justin Verlander | R | 23 | L 3-4 | @ CHA | 12 | 14 | L | 6.0 | 7 | 4 | 4 | 2 | 2 | 4 | 104 | 40 | 64 | 62% | 7-4 | 3.35 | 1.21 |
| 2006-06-08 | Kenny Rogers | L | 42 | W 6-2 | @ CHA | 13 | 413 | W | 7.0 | 6 | 2 | 2 | 1 | 0 | 5 | 94 | 33 | 61 | 65% | 8-3 | 3.47 | 1.19 |
| 2006-06-09 | Jeremy Bonderman | R | 24 | L 5-10 | @ TOR | 13 | 102 | - | 6.0 | 6 | 2 | 2 | 0 | 3 | 6 | 103 | 39 | 64 | 62% | 6-4 | 4.29 | 1.20 |
| 2006-06-10 | Zach Miner | R | 24 | W 5-3 | @ TOR | 2 | 2 | W | 6.0 | 4 | 2 | 2 | 1 | 2 | 5 | 100 | 37 | 63 | 63% | 1-1 | 4.50 | 1.50 |
| 2006-06-11 | Nate Robertson | R | 29 | W 10-5 | @ TOR | 13 | 85 | W | 5.0 | 5 | 4 | 4 | 3 | 3 | 8 | 106 | 47 | 59 | 56% | 6-3 | 3.49 | 1.34 |
| 2006-06-12 | Justin Verlander | R | 23 | L 4-3 | vs TBA | 13 | 15 | - | 6.0 | 3 | 2 | 2 | 1 | 3 | 2 | 97 | 42 | 55 | 57% | 7-4 | 3.32 | 1.19 |
| 2006-06-13 | Kenny Rogers | L | 42 | L 7-1 | vs TBA | 14 | 414 | W | 8.0 | 4 | 1 | 1 | 0 | 1 | 9 | 106 | 35 | 71 | 67% | 9-3 | 3.26 | 1.14 |
| 2006-06-14 | Jeremy Bonderman | R | 24 | W 1-5 | vs TBA | 14 | 103 | - | 8.0 | 6 | 1 | 1 | 0 | 1 | 12 | 111 | 41 | 70 | 63% | 6-4 | 4.01 | 1.17 |
| 2006-06-15 | Zach Miner | R | 24 | L 6-2 | vs TBA | 3 | 3 | W | 7.0 | 3 | 2 | 0 | 0 | 1 | 1 | 107 | 37 | 70 | 65% | 2-1 | 2.65 | 1.12 |
| 2006-06-16 | Nate Robertson | R | 29 | W 5-3 | @ CHN | 14 | 86 | W | 7.0 | 5 | 2 | 2 | 1 | 2 | 2 | 107 | 39 | 68 | 64% | 7-3 | 3.41 | 1.31 |
| 2006-06-17 | Justin Verlander | R | 23 | W 9-3 | @ CHN | 14 | 16 | W | 5.2 | 9 | 1 | 1 | 0 | 3 | 4 | 103 | 39 | 64 | 62% | 8-4 | 3.20 | 1.24 |
| 2006-06-18 | Kenny Rogers | L | 42 | W 12-3 | @ CHN | 15 | 415 | W | 8.0 | 4 | 2 | 2 | 2 | 1 | 2 | 101 | 38 | 63 | 62% | 10-3 | 3.18 | 1.10 |
| 2006-06-19 | Jeremy Bonderman | R | 24 | W 3-1 | @ MIL | 15 | 104 | W | 7.0 | 4 | 1 | 1 | 1 | 3 | 12 | 100 | 31 | 69 | 69% | 7-4 | 3.82 | 1.16 |
| 2006-06-20 | Zach Miner | R | 24 | W 10-1 | @ MIL | 4 | 4 | W | 9.0 | 5 | 1 | 1 | 0 | 2 | 5 | 112 | 45 | 67 | 60% | 3-1 | 2.08 | 1.00 |
| 2006-06-21 | Nate Robertson | R | 29 | L 3-4 | @ MIL | 15 | 87 | - | 6.2 | 7 | 3 | 2 | 0 | 0 | 7 | 92 | 32 | 60 | 65% | 7-3 | 3.39 | 1.30 |
| 2006-06-23 | Justin Verlander | R | 23 | L 10-6 | vs SLN | 15 | 17 | W | 6.0 | 7 | 4 | 4 | 0 | 3 | 5 | 108 | 38 | 70 | 65% | 9-4 | 3.38 | 1.27 |
| 2006-06-24 | Kenny Rogers | L | 42 | L 7-6 | vs SLN | 16 | 416 | - | 5.1 | 7 | 6 | 5 | 0 | 3 | 2 | 101 | 42 | 59 | 58% | 10-3 | 3.43 | 1.13 |
| 2006-06-25 | Jeremy Bonderman | R | 24 | L 4-1 | vs SLN | 16 | 105 | - | 7.0 | 7 | 1 | 1 | 0 | 1 | 8 | 115 | 36 | 79 | 69% | 7-4 | 3.65 | 1.16 |
| 2006-06-26 | Zach Miner | R | 24 | L 10-4 | vs HOU | 5 | 5 | W | 5.1 | 10 | 3 | 3 | 0 | 2 | 5 | 105 | 44 | 61 | 58% | 4-1 | 2.61 | 1.23 |
| 2006-06-27 | Nate Robertson | R | 29 | L 4-0 | vs HOU | 16 | 88 | W | 7.0 | 6 | 0 | 0 | 0 | 3 | 4 | 105 | 45 | 60 | 57% | 8-3 | 3.15 | 1.30 |
| 2006-06-28 | Justin Verlander | R | 23 | L 5-0 | vs HOU | 16 | 18 | W | 8.0 | 3 | 0 | 0 | 0 | 0 | 7 | 95 | 30 | 65 | 68% | 10-4 | 3.12 | 1.20 |
| 2006-06-30 | Kenny Rogers | L | 42 | W 7-6 | @ PIT | 17 | 417 | - | 4.1 | 8 | 5 | 5 | 1 | 0 | 2 | 73 | 25 | 48 | 66% | 10-3 | 3.72 | 1.17 |
| 2006-07-01 | Jeremy Bonderman | R | 24 | L 2-9 | @ PIT | 17 | 106 | - | 5.0 | 7 | 2 | 2 | 0 | 1 | 5 | 72 | 23 | 49 | 68% | 7-4 | 3.65 | 1.18 |
| 2006-07-02 | Zach Miner | R | 24 | W 9-8 | @ PIT | 6 | 6 | W | 5.2 | 6 | 2 | 2 | 0 | 1 | 5 | 91 | 36 | 55 | 60% | 5-1 | 2.68 | 1.22 |
| 2006-07-03 | Nate Robertson | R | 29 | L 3-5 | @ OAK | 17 | 89 | L | 7.0 | 7 | 5 | 5 | 1 | 4 | 3 | 106 | 44 | 62 | 58% | 8-4 | 3.36 | 1.32 |
| 2006-07-04 | Justin Verlander | R | 23 | L 1-2 | @ OAK | 17 | 19 | - | 7.0 | 3 | 1 | 1 | 0 | 2 | 4 | 102 | 36 | 66 | 65% | 10-4 | 3.00 | 1.17 |
| 2006-07-05 | Kenny Rogers | L | 42 | W 10-4 | @ OAK | 18 | 418 | W | 5.2 | 8 | 4 | 4 | 2 | 2 | 4 | 99 | 38 | 61 | 62% | 11-3 | 3.83 | 1.19 |
| 2006-07-07 | Jeremy Bonderman | R | 24 | W 6-1 | @ SEA | 18 | 107 | W | 8.2 | 6 | 1 | 1 | 0 | 0 | 4 | 109 | 27 | 82 | 75% | 8-4 | 3.45 | 1.14 |
| 2006-07-08 | Zach Miner | R | 24 | W 2-1 | @ SEA | 7 | 7 | W | 5.0 | 3 | 1 | 1 | 1 | 3 | 6 | 99 | 41 | 58 | 59% | 6-1 | 2.57 | 1.21 |
| 2006-07-09 | Nate Robertson | R | 29 | L 2-3 | @ SEA | 18 | 90 | L | 8.0 | 9 | 3 | 3 | 1 | 1 | 5 | 103 | 31 | 72 | 70% | 8-5 | 3.37 | 1.31 |
| 2006-07-13 | Jeremy Bonderman | R | 24 | L 6-4 | vs KCA | 19 | 108 | W | 5.2 | 7 | 4 | 4 | 2 | 5 | 8 | 108 | 39 | 69 | 64% | 9-4 | 3.60 | 1.19 |
| 2006-07-14 | Kenny Rogers | L | 42 | L 10-9 | vs KCA | 19 | 419 | - | 4.0 | 6 | 5 | 5 | 2 | 1 | 3 | 76 | 29 | 47 | 62% | 11-3 | 4.08 | 1.21 |
| 2006-07-15 | Justin Verlander | R | 23 | L 6-0 | vs KCA | 18 | 20 | W | 7.0 | 2 | 0 | 0 | 0 | 2 | 6 | 99 | 37 | 62 | 63% | 11-4 | 2.82 | 1.14 |
| 2006-07-16 | Zach Miner | R | 24 | W 6-9 | vs KCA | 8 | 8 | L | 4.1 | 8 | 5 | 5 | 0 | 2 | 1 | 94 | 37 | 57 | 61% | 6-2 | 3.33 | 1.33 |
| 2006-07-18 | Nate Robertson | R | 29 | W 1-7 | vs CHA | 19 | 91 | L | 6.2 | 9 | 6 | 6 | 2 | 1 | 6 | 105 | 37 | 68 | 65% | 8-6 | 3.61 | 1.32 |
| 2006-07-19 | Jeremy Bonderman | R | 24 | L 5-2 | vs CHA | 20 | 109 | W | 7.1 | 4 | 2 | 2 | 2 | 1 | 6 | 105 | 36 | 69 | 66% | 10-4 | 3.52 | 1.16 |
| 2006-07-20 | Kenny Rogers | L | 42 | L 2-1 | vs CHA | 20 | 420 | - | 6.0 | 6 | 1 | 1 | 0 | 3 | 3 | 87 | 32 | 55 | 63% | 11-3 | 3.96 | 1.22 |
| 2006-07-21 | Justin Verlander | R | 23 | L 7-4 | vs OAK | 19 | 21 | W | 6.0 | 7 | 1 | 1 | 0 | 1 | 5 | 103 | 39 | 64 | 62% | 12-4 | 2.76 | 1.15 |
| 2006-07-22 | Zach Miner | R | 24 | W 5-9 | vs OAK | 9 | 9 | - | 2.1 | 7 | 5 | 5 | 1 | 0 | 0 | 58 | 19 | 39 | 67% | 6-2 | 4.04 | 1.39 |
| 2006-07-23 | Nate Robertson | R | 29 | L 8-4 | vs OAK | 20 | 92 | W | 7.0 | 5 | 4 | 4 | 2 | 0 | 3 | 87 | 34 | 53 | 61% | 9-6 | 3.70 | 1.29 |
| 2006-07-24 | Jeremy Bonderman | R | 24 | W 9-7 | @ CLE | 21 | 110 | W | 5.0 | 5 | 4 | 4 | 2 | 2 | 7 | 93 | 38 | 55 | 59% | 11-4 | 3.65 | 1.17 |
| 2006-07-25 | Kenny Rogers | L | 42 | L 7-12 | @ CLE | 21 | 421 | L | 0.2 | 5 | 7 | 7 | 0 | 3 | 2 | 48 | 21 | 27 | 56% | 11-4 | 4.46 | 1.29 |
| 2006-07-26 | Justin Verlander | R | 23 | W 4-1 | @ CLE | 20 | 22 | W | 6.2 | 5 | 1 | 1 | 1 | 0 | 8 | 97 | 35 | 62 | 64% | 13-4 | 2.70 | 1.13 |
| 2006-07-28 | Zach Miner | R | 24 | W 3-2 | @ MIN | 10 | 10 | - | 6.0 | 4 | 2 | 2 | 0 | 2 | 5 | 108 | 43 | 65 | 60% | 6-2 | 3.93 | 1.35 |
| 2006-07-29 | Nate Robertson | R | 29 | W 8-6 | @ MIN | 21 | 93 | W | 6.0 | 9 | 5 | 5 | 2 | 1 | 4 | 91 | 33 | 58 | 64% | 10-6 | 3.87 | 1.30 |
| 2006-07-30 | Jeremy Bonderman | R | 24 | L 4-6 | @ MIN | 22 | 111 | L | 7.2 | 6 | 6 | 3 | 0 | 2 | 8 | 119 | 42 | 77 | 65% | 11-5 | 3.66 | 1.17 |
| 2006-07-31 | Kenny Rogers | L | 42 | L 3-7 | @ TBA | 22 | 422 | L | 5.0 | 5 | 6 | 5 | 2 | 4 | 3 | 108 | 49 | 59 | 55% | 11-5 | 4.64 | 1.31 |
| 2006-08-01 | Justin Verlander | R | 23 | W 10-4 | @ TBA | 21 | 23 | W | 5.0 | 8 | 3 | 3 | 0 | 2 | 4 | 91 | 33 | 58 | 64% | 14-4 | 2.80 | 1.16 |
| 2006-08-02 | Zach Miner | R | 24 | W 8-3 | @ TBA | 11 | 11 | - | 5.2 | 4 | 3 | 3 | 0 | 3 | 2 | 106 | 45 | 61 | 58% | 6-2 | 4.05 | 1.35 |
| 2006-08-03 | Nate Robertson | R | 29 | L 1-2 | @ TBA | 22 | 94 | L | 6.1 | 5 | 2 | 2 | 0 | 3 | 5 | 95 | 40 | 55 | 58% | 10-7 | 3.83 | 1.30 |
| 2006-08-04 | Jeremy Bonderman | R | 24 | L 7-6 | vs CLE | 23 | 112 | - | 5.2 | 7 | 5 | 5 | 1 | 3 | 6 | 111 | 42 | 69 | 62% | 11-5 | 3.81 | 1.19 |
| 2006-08-05 | Kenny Rogers | L | 42 | L 4-3 | vs CLE | 23 | 423 | - | 7.0 | 4 | 3 | 3 | 2 | 2 | 3 | 110 | 46 | 64 | 58% | 11-5 | 4.60 | 1.28 |
| 2006-08-06 | Wil Ledezma | L | 26 | L 1-0 | vs CLE | 1 | 27 | W | 5.2 | 6 | 0 | 0 | 0 | 2 | 5 | 92 | 33 | 59 | 64% | 2-1 | 3.00 | 1.43 |
| 2006-08-07 | Zach Miner | R | 24 | L 9-3 | vs MIN | 12 | 12 | W | 6.1 | 7 | 3 | 3 | 1 | 0 | 3 | 81 | 27 | 54 | 67% | 7-2 | 4.03 | 1.31 |
| 2006-08-08 | Nate Robertson | R | 29 | W 2-4 | vs MIN | 23 | 95 | L | 7.0 | 7 | 3 | 3 | 0 | 3 | 2 | 116 | 46 | 70 | 60% | 10-8 | 3.83 | 1.31 |
| 2006-08-09 | Jeremy Bonderman | R | 24 | W 3-4 | vs MIN | 24 | 113 | - | 7.0 | 8 | 2 | 2 | 0 | 2 | 5 | 95 | 33 | 62 | 65% | 11-5 | 3.76 | 1.20 |
| 2006-08-11 | Justin Verlander | R | 23 | L 0-5 | @ CHA | 22 | 24 | L | 5.0 | 13 | 5 | 4 | 2 | 0 | 4 | 100 | 34 | 66 | 66% | 14-5 | 2.96 | 1.21 |
| 2006-08-12 | Kenny Rogers | L | 42 | L 3-4 | @ CHA | 24 | 424 | L | 7.0 | 4 | 4 | 0 | 0 | 0 | 2 | 95 | 36 | 59 | 62% | 11-6 | 4.38 | 1.25 |
| 2006-08-13 | Zach Miner | R | 24 | L 3-7 | @ CHA | 13 | 13 | L | 5.1 | 5 | 4 | 4 | 0 | 3 | 2 | 119 | 49 | 70 | 59% | 7-3 | 4.25 | 1.33 |
| 2006-08-14 | Nate Robertson | R | 29 | W 7-4 | @ BOS | 24 | 96 | W | 6.0 | 5 | 3 | 3 | 1 | 2 | 5 | 102 | 41 | 61 | 60% | 11-8 | 3.86 | 1.31 |
| 2006-08-15 | Jeremy Bonderman | R | 24 | W 3-2 | @ BOS | 25 | 114 | - | 7.2 | 5 | 2 | 2 | 1 | 1 | 8 | 102 | 40 | 62 | 61% | 11-5 | 3.69 | 1.17 |
| 2006-08-16 | Justin Verlander | R | 23 | L 4-6 | @ BOS | 23 | 25 | L | 6.0 | 6 | 5 | 5 | 1 | 7 | 2 | 104 | 47 | 57 | 55% | 14-6 | 3.14 | 1.25 |
| 2006-08-17 | Kenny Rogers | L | 42 | L 4-2 | vs TEX | 25 | 425 | W | 5.0 | 5 | 2 | 2 | 0 | 4 | 1 | 81 | 32 | 49 | 60% | 12-6 | 4.35 | 1.27 |
| 2006-08-18 | Zach Miner | R | 24 | W 1-2 | vs TEX | 14 | 14 | L | 6.0 | 8 | 2 | 2 | 1 | 1 | 3 | 100 | 39 | 61 | 61% | 7-4 | 4.15 | 1.35 |
| 2006-08-19 | Nate Robertson | R | 29 | W 1-3 | vs TEX | 25 | 97 | L | 8.0 | 2 | 3 | 1 | 1 | 2 | 3 | 106 | 37 | 69 | 65% | 11-9 | 3.72 | 1.27 |
| 2006-08-20 | Jeremy Bonderman | R | 24 | W 6-7 | vs TEX | 26 | 115 | - | 4.2 | 11 | 6 | 5 | 0 | 2 | 4 | 101 | 30 | 71 | 70% | 11-5 | 3.86 | 1.22 |
| 2006-08-21 | Justin Verlander | R | 23 | L 7-1 | vs CHA | 24 | 26 | W | 7.0 | 5 | 1 | 1 | 1 | 2 | 2 | 103 | 41 | 62 | 60% | 15-6 | 3.06 | 1.24 |
| 2006-08-22 | Kenny Rogers | L | 42 | L 4-0 | vs CHA | 26 | 426 | W | 7.0 | 4 | 0 | 0 | 0 | 1 | 2 | 96 | 29 | 67 | 70% | 13-6 | 4.15 | 1.24 |
| 2006-08-23 | Zach Miner | R | 24 | W 5-7 | vs CHA | 15 | 15 | L | 1.1 | 4 | 6 | 6 | 2 | 2 | 1 | 40 | 18 | 22 | 55% | 7-5 | 4.78 | 1.41 |
| 2006-08-24 | Nate Robertson | R | 29 | W 0-10 | vs CHA | 26 | 98 | L | 6.2 | 9 | 10 | 10 | 3 | 2 | 6 | 87 | 29 | 58 | 67% | 11-10 | 4.10 | 1.28 |
| 2006-08-25 | Jeremy Bonderman | R | 24 | L 2-4 | @ CLE | 27 | 116 | L | 6.1 | 7 | 4 | 4 | 0 | 2 | 9 | 116 | 45 | 71 | 61% | 11-6 | 3.92 | 1.23 |
| 2006-08-26 | Justin Verlander | R | 24 | L 5-8 | @ CLE | 25 | 27 | L | 4.2 | 10 | 8 | 8 | 0 | 1 | 6 | 103 | 36 | 67 | 65% | 15-7 | 3.42 | 1.27 |
| 2006-08-27 | Kenny Rogers | L | 42 | W 7-1 | @ CLE | 27 | 427 | W | 7.0 | 4 | 1 | 1 | 0 | 3 | 3 | 106 | 45 | 61 | 58% | 14-6 | 4.03 | 1.23 |
| 2006-08-30 | Nate Robertson | R | 29 | L 0-2 | @ NYA | 27 | 99 | L | 7.0 | 10 | 2 | 2 | 1 | 2 | 4 | 107 | 36 | 71 | 66% | 11-11 | 4.04 | 1.30 |
| 2006-08-30 | Wil Ledezma | L | 26 | W 5-3 | @ NYA | 2 | 28 | - | 5.1 | 2 | 2 | 2 | 0 | 1 | 2 | 68 | 27 | 41 | 60% | 2-1 | 2.25 | 1.25 |
| 2006-08-31 | Jeremy Bonderman | R | 24 | L 4-6 | @ NYA | 28 | 117 | L | 5.1 | 11 | 4 | 4 | 0 | 3 | 5 | 109 | 47 | 62 | 57% | 11-7 | 4.01 | 1.27 |
| 2006-09-01 | Kenny Rogers | L | 42 | L 9-0 | vs ANA | 28 | 428 | W | 7.0 | 4 | 0 | 0 | 0 | 2 | 2 | 106 | 44 | 62 | 58% | 15-6 | 3.86 | 1.22 |
| 2006-09-02 | Justin Verlander | R | 24 | W 2-7 | vs ANA | 26 | 28 | - | 7.0 | 4 | 0 | 0 | 0 | 4 | 6 | 126 | 51 | 75 | 60% | 15-7 | 3.27 | 1.27 |
| 2006-09-03 | Wil Ledezma | L | 26 | W 1-2 | vs ANA | 3 | 29 | L | 6.0 | 3 | 2 | 2 | 1 | 3 | 2 | 69 | 27 | 42 | 61% | 2-2 | 2.36 | 1.21 |
| 2006-09-04 | Nate Robertson | R | 29 | L 6-2 | vs SEA | 28 | 100 | W | 7.0 | 8 | 1 | 1 | 0 | 2 | 4 | 100 | 31 | 69 | 69% | 12-11 | 3.93 | 1.30 |
| 2006-09-05 | Jeremy Bonderman | R | 24 | W 3-4 | vs SEA | 29 | 118 | - | 4.0 | 6 | 3 | 2 | 0 | 1 | 4 | 60 | 23 | 37 | 62% | 11-7 | 4.02 | 1.28 |
| 2006-09-06 | Kenny Rogers | L | 42 | W 4-5 | vs SEA | 29 | 429 | - | 7.0 | 8 | 4 | 4 | 0 | 1 | 1 | 92 | 38 | 54 | 59% | 15-6 | 3.92 | 1.22 |
| 2006-09-07 | Justin Verlander | R | 24 | W 7-2 | @ MIN | 27 | 29 | W | 7.0 | 8 | 1 | 1 | 1 | 2 | 5 | 109 | 39 | 70 | 64% | 16-7 | 3.19 | 1.27 |
| 2006-09-08 | Wil Ledezma | L | 26 | L 5-9 | @ MIN | 4 | 30 | L | 4.1 | 9 | 5 | 5 | 0 | 1 | 1 | 76 | 22 | 54 | 71% | 2-3 | 3.13 | 1.33 |
| 2006-09-09 | Nate Robertson | R | 29 | L 1-2 | @ MIN | 29 | 101 | L | 7.0 | 6 | 2 | 1 | 0 | 1 | 5 | 102 | 37 | 65 | 64% | 12-12 | 3.84 | 1.29 |
| 2006-09-10 | Jeremy Bonderman | R | 24 | L 1-12 | @ MIN | 30 | 119 | L | 5.2 | 8 | 7 | 6 | 0 | 3 | 6 | 116 | 46 | 70 | 60% | 11-8 | 4.17 | 1.30 |
| 2006-09-12 | Kenny Rogers | L | 42 | L 3-2 | vs TEX | 30 | 430 | - | 7.0 | 10 | 2 | 2 | 1 | 2 | 2 | 95 | 35 | 60 | 63% | 15-6 | 3.86 | 1.24 |
| 2006-09-13 | Justin Verlander | R | 24 | W 3-11 | vs TEX | 28 | 30 | L | 4.1 | 10 | 6 | 6 | 1 | 1 | 2 | 80 | 31 | 49 | 61% | 16-8 | 3.43 | 1.31 |
| 2006-09-15 | Jeremy Bonderman | R | 24 | L 17-2 | vs BAL | 31 | 120 | W | 6.0 | 7 | 2 | 2 | 2 | 2 | 7 | 92 | 36 | 56 | 61% | 12-8 | 4.14 | 1.30 |
| 2006-09-16 | Nate Robertson | R | 29 | L 2-0 | vs BAL | 30 | 102 | W | 8.0 | 6 | 0 | 0 | 0 | 1 | 5 | 93 | 28 | 65 | 70% | 13-12 | 3.68 | 1.27 |
| 2006-09-17 | Wil Ledezma | L | 26 | W 8-12 | vs BAL | 5 | 31 | - | 3.2 | 7 | 5 | 5 | 3 | 1 | 2 | 68 | 21 | 47 | 69% | 2-3 | 3.78 | 1.38 |
| 2006-09-18 | Kenny Rogers | L | 42 | W 8-2 | @ CHA | 31 | 431 | W | 6.0 | 4 | 0 | 0 | 0 | 4 | 2 | 101 | 45 | 56 | 55% | 16-6 | 3.74 | 1.24 |
| 2006-09-19 | Justin Verlander | R | 24 | L 0-7 | @ CHA | 29 | 31 | L | 4.2 | 6 | 6 | 6 | 3 | 3 | 2 | 94 | 42 | 52 | 55% | 16-9 | 3.63 | 1.32 |
| 2006-09-20 | Jeremy Bonderman | R | 24 | W 6-2 | @ CHA | 32 | 121 | W | 6.0 | 5 | 2 | 2 | 2 | 1 | 2 | 89 | 35 | 54 | 61% | 13-8 | 4.10 | 1.29 |
| 2006-09-21 | Nate Robertson | R | 29 | L 3-4 | @ BAL | 31 | 103 | - | 6.0 | 5 | 2 | 2 | 0 | 5 | 5 | 105 | 45 | 60 | 57% | 13-12 | 3.66 | 1.28 |
| 2006-09-22 | Wil Ledezma | L | 26 | W 7-3 | @ KCA | 6 | 32 | W | 5.2 | 4 | 3 | 1 | 0 | 3 | 4 | 103 | 48 | 55 | 53% | 3-3 | 3.60 | 1.38 |
| 2006-09-23 | Kenny Rogers | L | 42 | W 15-4 | @ KCA | 32 | 432 | W | 8.0 | 5 | 1 | 1 | 1 | 1 | 3 | 89 | 28 | 61 | 69% | 17-6 | 3.64 | 1.22 |
| 2006-09-24 | Justin Verlander | R | 24 | W 11-4 | @ KCA | 30 | 32 | W | 5.0 | 6 | 2 | 2 | 0 | 2 | 3 | 86 | 31 | 55 | 64% | 17-9 | 3.63 | 1.33 |
| 2006-09-26 | Jeremy Bonderman | R | 24 | L 4-3 | vs TOR | 33 | 122 | W | 6.0 | 3 | 1 | 0 | 0 | 3 | 4 | 102 | 45 | 57 | 56% | 14-8 | 3.99 | 1.29 |
| 2006-09-27 | Nate Robertson | R | 29 | W 4-7 | vs TOR | 32 | 104 | L | 4.2 | 10 | 6 | 6 | 4 | 1 | 2 | 89 | 29 | 60 | 67% | 13-13 | 3.83 | 1.31 |
| 2006-09-28 | Kenny Rogers | L | 42 | W 6-8 | vs TOR | 33 | 433 | L | 3.2 | 8 | 7 | 5 | 0 | 1 | 2 | 70 | 25 | 45 | 64% | 17-7 | 3.79 | 1.24 |
| 2006-09-29 | Wil Ledezma | L | 26 | W 7-9 | vs KCA | 7 | 33 | - | 5.0 | 6 | 2 | 2 | 0 | 1 | 3 | 69 | 25 | 44 | 64% | 3-3 | 3.60 | 1.38 |
| 2006-09-30 | Zach Miner | R | 25 | W 6-9 | vs KCA | 16 | 16 | L | 0.1 | 5 | 5 | 5 | 1 | 0 | 0 | 32 | 13 | 19 | 59% | 7-6 | 4.84 | 1.42 |
| 2006-10-01 | Jeremy Bonderman | R | 24 | W 8-10 | vs KCA | 34 | 123 | - | 4.1 | 7 | 4 | 4 | 0 | 1 | 2 | 68 | 25 | 43 | 63% | 14-8 | 4.08 | 1.30 |