| East | W | L | Pct | GB |
| NY Yankees | 101 | 61 | .623 | -- |
| Boston | 98 | 64 | .605 | 3.0 |
| Baltimore | 78 | 84 | .481 | 23.0 |
| Tampa Bay | 70 | 91 | .435 | 30.5 |
| Toronto | 67 | 94 | .416 | 33.5 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2004-04-04 | Pedro Martinez | R | 32 | L 2-7 | @ BAL | 1 | 289 | L | 6.0 | 7 | 3 | 2 | 1 | 1 | 5 | 97 | 38 | 59 | 61% | 0-1 | 3.00 | 1.33 |
| 2004-04-06 | Curt Schilling | R | 37 | W 4-1 | @ BAL | 1 | 339 | W | 6.0 | 6 | 1 | 1 | 0 | 1 | 7 | 111 | 35 | 76 | 68% | 1-0 | 1.50 | 1.17 |
| 2004-04-07 | Derek Lowe | R | 31 | W 10-3 | @ BAL | 1 | 88 | W | 6.0 | 7 | 2 | 2 | 0 | 2 | 3 | 95 | 36 | 59 | 62% | 1-0 | 3.00 | 1.50 |
| 2004-04-08 | Tim Wakefield | R | 38 | L 2-3 | @ BAL | 1 | 254 | - | 5.1 | 3 | 2 | 2 | 0 | 5 | 5 | 107 | 49 | 58 | 54% | 0-0 | 3.60 | 1.60 |
| 2004-04-09 | Bronson Arroyo | R | 27 | W 5-10 | vs TOR | 1 | 30 | - | 6.0 | 8 | 4 | 4 | 0 | 3 | 4 | 97 | 37 | 60 | 62% | 0-0 | 6.00 | 1.83 |
| 2004-04-10 | Pedro Martinez | R | 32 | L 4-1 | vs TOR | 2 | 290 | W | 7.2 | 4 | 1 | 1 | 1 | 2 | 7 | 106 | 35 | 71 | 67% | 1-1 | 1.93 | 1.00 |
| 2004-04-11 | Curt Schilling | R | 37 | L 6-4 | vs TOR | 2 | 340 | - | 8.0 | 6 | 4 | 4 | 1 | 0 | 10 | 116 | 35 | 81 | 70% | 1-0 | 3.21 | 0.93 |
| 2004-04-15 | Pedro Martinez | R | 32 | W 7-12 | vs BAL | 3 | 291 | - | 5.0 | 8 | 7 | 7 | 2 | 4 | 3 | 103 | 42 | 61 | 59% | 1-1 | 4.74 | 1.37 |
| 2004-04-16 | Tim Wakefield | R | 38 | L 6-2 | vs NYA | 2 | 255 | W | 7.0 | 4 | 2 | 1 | 1 | 4 | 4 | 106 | 42 | 64 | 60% | 1-0 | 2.25 | 1.33 |
| 2004-04-17 | Curt Schilling | R | 37 | L 5-2 | vs NYA | 3 | 341 | W | 6.1 | 6 | 1 | 1 | 1 | 4 | 8 | 121 | 39 | 82 | 68% | 2-0 | 2.70 | 1.15 |
| 2004-04-18 | Derek Lowe | R | 31 | W 3-7 | vs NYA | 2 | 89 | L | 2.2 | 8 | 7 | 7 | 0 | 4 | 2 | 75 | 32 | 43 | 57% | 1-1 | 9.00 | 2.33 |
| 2004-04-19 | Bronson Arroyo | R | 27 | L 5-4 | vs NYA | 2 | 31 | - | 6.1 | 8 | 4 | 4 | 1 | 1 | 5 | 99 | 29 | 70 | 71% | 0-1 | 6.92 | 1.85 |
| 2004-04-20 | Pedro Martinez | R | 32 | W 4-2 | @ TOR | 4 | 292 | W | 7.0 | 5 | 2 | 1 | 0 | 2 | 6 | 104 | 37 | 67 | 64% | 2-1 | 3.81 | 1.27 |
| 2004-04-21 | Tim Wakefield | R | 38 | W 4-2 | @ TOR | 3 | 256 | W | 6.2 | 6 | 2 | 2 | 0 | 2 | 4 | 112 | 42 | 70 | 63% | 2-0 | 2.37 | 1.26 |
| 2004-04-22 | Curt Schilling | R | 37 | L 3-7 | @ TOR | 4 | 342 | L | 7.2 | 13 | 7 | 7 | 1 | 1 | 6 | 125 | 36 | 89 | 71% | 2-1 | 4.18 | 1.32 |
| 2004-04-23 | Derek Lowe | R | 31 | W 11-2 | @ NYA | 3 | 90 | W | 6.0 | 6 | 2 | 2 | 1 | 2 | 2 | 99 | 43 | 56 | 57% | 2-1 | 6.60 | 1.93 |
| 2004-04-24 | Bronson Arroyo | R | 27 | W 3-2 | @ NYA | 3 | 32 | - | 6.0 | 4 | 2 | 2 | 1 | 2 | 4 | 85 | 36 | 49 | 58% | 0-1 | 5.68 | 1.58 |
| 2004-04-25 | Pedro Martinez | R | 33 | W 2-0 | @ NYA | 5 | 293 | W | 7.0 | 4 | 0 | 0 | 0 | 1 | 7 | 110 | 38 | 72 | 65% | 3-1 | 3.00 | 1.15 |
| 2004-04-28 | Curt Schilling | R | 37 | L 6-0 | vs TBA | 5 | 343 | W | 7.1 | 5 | 0 | 0 | 0 | 0 | 8 | 106 | 30 | 76 | 72% | 3-1 | 3.34 | 1.20 |
| 2004-04-29 | Byung-Hyun Kim | R | 25 | L 4-0 | vs TBA | 1 | 14 | W | 5.0 | 1 | 0 | 0 | 0 | 1 | 2 | 69 | 26 | 43 | 62% | 1-0 | 0.00 | 0.40 |
| 2004-04-29 | Derek Lowe | R | 31 | L 7-3 | vs TBA | 4 | 91 | W | 7.0 | 9 | 3 | 1 | 0 | 1 | 3 | 100 | 33 | 67 | 67% | 3-1 | 4.91 | 1.77 |
| 2004-05-01 | Bronson Arroyo | R | 27 | L 3-4 | @ TEX | 4 | 33 | - | 6.0 | 3 | 2 | 2 | 0 | 2 | 5 | 85 | 33 | 52 | 61% | 0-1 | 5.04 | 1.40 |
| 2004-05-01 | Pedro Martinez | R | 33 | L 5-8 | @ TEX | 6 | 294 | L | 4.0 | 9 | 6 | 6 | 1 | 1 | 3 | 90 | 41 | 49 | 54% | 3-2 | 4.14 | 1.30 |
| 2004-05-02 | Tim Wakefield | R | 38 | L 1-4 | @ TEX | 4 | 257 | L | 7.0 | 5 | 2 | 2 | 1 | 0 | 4 | 101 | 37 | 64 | 63% | 2-1 | 2.25 | 1.11 |
| 2004-05-03 | Curt Schilling | R | 37 | L 1-2 | @ CLE | 6 | 344 | L | 7.0 | 7 | 2 | 2 | 1 | 1 | 6 | 103 | 32 | 71 | 69% | 3-2 | 3.21 | 1.19 |
| 2004-05-04 | Derek Lowe | R | 31 | L 6-7 | @ CLE | 5 | 92 | L | 5.0 | 10 | 7 | 2 | 0 | 2 | 2 | 78 | 28 | 50 | 64% | 3-2 | 4.67 | 1.89 |
| 2004-05-05 | Byung-Hyun Kim | R | 25 | W 9-5 | @ CLE | 2 | 15 | - | 3.1 | 6 | 5 | 4 | 1 | 1 | 2 | 68 | 24 | 44 | 65% | 1-0 | 4.50 | 1.13 |
| 2004-05-06 | Pedro Martinez | R | 33 | W 5-2 | @ CLE | 7 | 295 | W | 7.0 | 4 | 2 | 2 | 1 | 3 | 8 | 92 | 30 | 62 | 67% | 4-2 | 3.89 | 1.25 |
| 2004-05-07 | Tim Wakefield | R | 38 | L 7-6 | vs KCA | 5 | 258 | - | 8.0 | 9 | 6 | 4 | 0 | 2 | 3 | 113 | 43 | 70 | 62% | 2-1 | 2.75 | 1.17 |
| 2004-05-08 | Curt Schilling | R | 37 | L 9-1 | vs KCA | 7 | 345 | W | 9.0 | 5 | 1 | 1 | 1 | 0 | 8 | 120 | 35 | 85 | 71% | 4-2 | 2.82 | 1.08 |
| 2004-05-09 | Derek Lowe | R | 31 | W 4-8 | vs KCA | 6 | 93 | L | 5.2 | 5 | 6 | 4 | 0 | 5 | 3 | 103 | 46 | 57 | 55% | 3-3 | 5.06 | 1.91 |
| 2004-05-10 | Byung-Hyun Kim | R | 25 | W 6-10 | vs CLE | 3 | 16 | L | 3.1 | 5 | 6 | 4 | 0 | 3 | 0 | 80 | 36 | 44 | 55% | 1-1 | 6.00 | 1.42 |
| 2004-05-11 | Pedro Martinez | R | 33 | L 5-3 | vs CLE | 8 | 296 | - | 7.0 | 5 | 2 | 2 | 0 | 2 | 11 | 115 | 44 | 71 | 62% | 4-2 | 3.71 | 1.22 |
| 2004-05-12 | Tim Wakefield | R | 38 | W 4-6 | vs CLE | 6 | 259 | L | 6.0 | 8 | 6 | 6 | 1 | 1 | 6 | 91 | 26 | 65 | 71% | 2-2 | 3.64 | 1.21 |
| 2004-05-13 | Curt Schilling | R | 37 | L 6-12 | @ TOR | 8 | 346 | L | 5.0 | 8 | 3 | 3 | 0 | 2 | 3 | 103 | 38 | 65 | 63% | 4-3 | 3.05 | 1.16 |
| 2004-05-14 | Derek Lowe | R | 31 | W 9-3 | @ TOR | 7 | 94 | - | 5.2 | 4 | 3 | 2 | 0 | 4 | 2 | 103 | 44 | 59 | 57% | 3-3 | 4.74 | 1.82 |
| 2004-05-15 | Bronson Arroyo | R | 27 | W 4-0 | @ TOR | 5 | 34 | W | 8.0 | 3 | 0 | 0 | 0 | 0 | 6 | 100 | 30 | 70 | 70% | 2-1 | 3.50 | 1.08 |
| 2004-05-16 | Pedro Martinez | R | 33 | L 1-3 | @ TOR | 9 | 297 | L | 7.0 | 6 | 3 | 3 | 1 | 1 | 6 | 109 | 40 | 69 | 63% | 4-3 | 3.72 | 1.19 |
| 2004-05-18 | Tim Wakefield | R | 38 | W 7-3 | @ TBA | 7 | 260 | W | 7.0 | 3 | 1 | 1 | 0 | 2 | 2 | 106 | 34 | 72 | 68% | 3-2 | 3.31 | 1.14 |
| 2004-05-19 | Curt Schilling | R | 38 | W 4-1 | @ TBA | 9 | 347 | W | 7.0 | 5 | 1 | 1 | 0 | 1 | 5 | 113 | 34 | 79 | 70% | 5-3 | 2.86 | 1.13 |
| 2004-05-20 | Derek Lowe | R | 31 | L 6-9 | @ TBA | 8 | 95 | L | 2.1 | 8 | 7 | 7 | 0 | 0 | 1 | 59 | 15 | 44 | 75% | 3-4 | 6.08 | 1.93 |
| 2004-05-21 | Bronson Arroyo | R | 27 | L 11-5 | vs TOR | 6 | 35 | - | 6.0 | 7 | 5 | 5 | 3 | 1 | 2 | 98 | 36 | 62 | 63% | 2-1 | 4.07 | 1.12 |
| 2004-05-22 | Pedro Martinez | R | 33 | L 5-2 | vs TOR | 10 | 298 | - | 6.0 | 5 | 2 | 2 | 0 | 1 | 7 | 106 | 37 | 69 | 65% | 4-3 | 3.66 | 1.17 |
| 2004-05-23 | Tim Wakefield | R | 38 | L 7-2 | vs TOR | 8 | 261 | W | 7.0 | 7 | 2 | 2 | 0 | 1 | 4 | 89 | 31 | 58 | 65% | 4-2 | 3.21 | 1.14 |
| 2004-05-25 | Curt Schilling | R | 38 | L 12-2 | vs OAK | 10 | 348 | W | 7.0 | 9 | 2 | 2 | 0 | 0 | 5 | 113 | 36 | 77 | 68% | 6-3 | 2.83 | 1.14 |
| 2004-05-26 | Derek Lowe | R | 31 | L 9-6 | vs OAK | 9 | 96 | W | 6.0 | 9 | 5 | 5 | 1 | 1 | 3 | 96 | 38 | 58 | 60% | 4-4 | 6.26 | 1.89 |
| 2004-05-27 | Bronson Arroyo | R | 27 | W 2-15 | vs OAK | 7 | 36 | L | 3.1 | 7 | 9 | 6 | 1 | 2 | 2 | 72 | 28 | 44 | 61% | 2-2 | 5.00 | 1.24 |
| 2004-05-28 | Pedro Martinez | R | 33 | L 8-4 | vs SEA | 11 | 299 | W | 7.0 | 8 | 4 | 4 | 2 | 0 | 9 | 111 | 37 | 74 | 67% | 5-3 | 3.80 | 1.17 |
| 2004-05-29 | Tim Wakefield | R | 38 | W 4-5 | vs SEA | 9 | 262 | L | 6.2 | 10 | 5 | 5 | 1 | 3 | 2 | 103 | 29 | 74 | 72% | 4-3 | 3.57 | 1.22 |
| 2004-05-30 | Curt Schilling | R | 38 | L 9-7 | vs SEA | 11 | 349 | - | 7.2 | 5 | 4 | 4 | 0 | 1 | 4 | 101 | 30 | 71 | 70% | 6-3 | 3.00 | 1.10 |
| 2004-05-31 | Derek Lowe | R | 31 | W 4-13 | vs BAL | 10 | 97 | L | 5.0 | 8 | 7 | 7 | 1 | 4 | 0 | 85 | 33 | 52 | 61% | 4-5 | 6.88 | 1.94 |
| 2004-06-01 | Bronson Arroyo | R | 27 | L 6-7 | @ ANA | 8 | 37 | L | 5.2 | 8 | 6 | 5 | 0 | 2 | 5 | 114 | 39 | 75 | 66% | 2-3 | 5.29 | 1.29 |
| 2004-06-02 | Pedro Martinez | R | 33 | L 7-10 | @ ANA | 12 | 300 | - | 5.0 | 11 | 7 | 7 | 1 | 2 | 4 | 107 | 29 | 78 | 73% | 5-3 | 4.38 | 1.26 |
| 2004-06-04 | Tim Wakefield | R | 38 | L 2-5 | @ KCA | 10 | 263 | L | 6.2 | 9 | 5 | 4 | 0 | 4 | 4 | 125 | 49 | 76 | 61% | 4-4 | 3.78 | 1.30 |
| 2004-06-05 | Curt Schilling | R | 38 | W 8-4 | @ KCA | 12 | 350 | W | 7.0 | 6 | 3 | 3 | 1 | 1 | 3 | 104 | 35 | 69 | 66% | 7-3 | 3.07 | 1.09 |
| 2004-06-06 | Derek Lowe | R | 31 | W 5-3 | @ KCA | 11 | 98 | W | 5.0 | 3 | 3 | 2 | 1 | 1 | 4 | 83 | 36 | 47 | 57% | 5-5 | 6.59 | 1.84 |
| 2004-06-08 | Pedro Martinez | R | 33 | L 1-0 | vs SDN | 13 | 301 | W | 8.0 | 2 | 0 | 0 | 0 | 1 | 8 | 114 | 41 | 73 | 64% | 6-3 | 3.96 | 1.18 |
| 2004-06-09 | Bronson Arroyo | R | 27 | W 1-8 | vs SDN | 9 | 38 | L | 5.0 | 6 | 2 | 1 | 0 | 2 | 1 | 90 | 30 | 60 | 67% | 2-4 | 4.98 | 1.32 |
| 2004-06-10 | Curt Schilling | R | 38 | L 9-3 | vs SDN | 13 | 351 | W | 7.0 | 6 | 2 | 2 | 0 | 2 | 8 | 90 | 29 | 61 | 68% | 8-3 | 3.03 | 1.10 |
| 2004-06-11 | Derek Lowe | R | 31 | L 2-1 | vs LAN | 12 | 99 | - | 7.0 | 5 | 0 | 0 | 0 | 4 | 4 | 103 | 46 | 57 | 55% | 5-5 | 5.86 | 1.78 |
| 2004-06-12 | Tim Wakefield | R | 38 | W 5-14 | vs LAN | 11 | 264 | L | 4.1 | 10 | 8 | 8 | 2 | 3 | 2 | 96 | 41 | 55 | 57% | 4-5 | 4.44 | 1.40 |
| 2004-06-13 | Pedro Martinez | R | 33 | L 4-1 | vs LAN | 14 | 302 | W | 7.0 | 7 | 1 | 1 | 0 | 2 | 5 | 112 | 38 | 74 | 66% | 7-3 | 3.76 | 1.19 |
| 2004-06-15 | Bronson Arroyo | R | 27 | L 3-6 | @ COL | 10 | 39 | L | 6.0 | 7 | 4 | 3 | 1 | 1 | 4 | 90 | 29 | 61 | 68% | 2-5 | 4.94 | 1.32 |
| 2004-06-16 | Curt Schilling | R | 38 | L 6-7 | @ COL | 14 | 352 | L | 6.0 | 9 | 7 | 5 | 0 | 4 | 7 | 113 | 38 | 75 | 66% | 8-4 | 3.31 | 1.16 |
| 2004-06-17 | Derek Lowe | R | 31 | W 11-0 | @ COL | 13 | 100 | W | 7.0 | 4 | 0 | 0 | 0 | 4 | 3 | 92 | 35 | 57 | 62% | 6-5 | 5.27 | 1.71 |
| 2004-06-18 | Tim Wakefield | R | 38 | W 14-9 | @ SFN | 12 | 265 | - | 4.0 | 4 | 7 | 6 | 2 | 4 | 3 | 76 | 30 | 46 | 61% | 4-5 | 4.90 | 1.43 |
| 2004-06-19 | Pedro Martinez | R | 33 | L 4-6 | @ SFN | 15 | 303 | - | 6.0 | 6 | 4 | 4 | 1 | 2 | 6 | 99 | 37 | 62 | 63% | 7-3 | 3.90 | 1.20 |
| 2004-06-20 | Bronson Arroyo | R | 27 | L 0-4 | @ SFN | 11 | 40 | L | 6.1 | 4 | 2 | 2 | 0 | 5 | 7 | 126 | 52 | 74 | 59% | 2-6 | 4.76 | 1.34 |
| 2004-06-22 | Curt Schilling | R | 38 | L 9-2 | vs MIN | 15 | 353 | W | 7.0 | 4 | 1 | 1 | 0 | 0 | 5 | 99 | 28 | 71 | 72% | 9-4 | 3.17 | 1.12 |
| 2004-06-23 | Derek Lowe | R | 31 | W 2-4 | vs MIN | 14 | 101 | L | 7.0 | 7 | 4 | 4 | 1 | 1 | 7 | 107 | 35 | 72 | 67% | 6-6 | 5.26 | 1.66 |
| 2004-06-24 | Tim Wakefield | R | 38 | W 3-4 | vs MIN | 13 | 266 | - | 7.2 | 8 | 3 | 1 | 0 | 1 | 4 | 91 | 27 | 64 | 70% | 4-5 | 4.60 | 1.42 |
| 2004-06-25 | Pedro Martinez | R | 33 | L 12-1 | vs PHI | 16 | 304 | W | 7.0 | 2 | 1 | 1 | 1 | 2 | 2 | 98 | 33 | 65 | 66% | 8-3 | 3.72 | 1.15 |
| 2004-06-26 | Bronson Arroyo | R | 27 | W 2-9 | vs PHI | 12 | 41 | L | 5.0 | 7 | 7 | 2 | 1 | 3 | 5 | 98 | 35 | 63 | 64% | 2-7 | 4.68 | 1.38 |
| 2004-06-27 | Curt Schilling | R | 38 | L 12-3 | vs PHI | 16 | 354 | W | 6.0 | 8 | 3 | 3 | 2 | 2 | 7 | 108 | 38 | 70 | 65% | 10-4 | 3.24 | 1.15 |
| 2004-06-29 | Derek Lowe | R | 31 | L 3-11 | @ NYA | 15 | 102 | L | 5.0 | 9 | 9 | 5 | 2 | 1 | 1 | 104 | 41 | 63 | 61% | 6-7 | 5.49 | 1.68 |
| 2004-06-30 | Tim Wakefield | R | 38 | L 2-4 | @ NYA | 14 | 267 | - | 6.1 | 3 | 2 | 0 | 0 | 2 | 3 | 101 | 45 | 56 | 55% | 4-5 | 4.26 | 1.37 |
| 2004-07-01 | Pedro Martinez | R | 33 | L 4-5 | @ NYA | 17 | 305 | - | 7.0 | 4 | 3 | 3 | 2 | 3 | 8 | 110 | 40 | 70 | 64% | 8-3 | 3.73 | 1.14 |
| 2004-07-02 | Bronson Arroyo | R | 27 | L 3-6 | @ ATL | 13 | 42 | - | 7.0 | 5 | 2 | 2 | 2 | 2 | 5 | 90 | 34 | 56 | 62% | 2-7 | 4.50 | 1.35 |
| 2004-07-03 | Curt Schilling | R | 38 | W 6-1 | @ ATL | 17 | 355 | W | 9.0 | 6 | 1 | 1 | 0 | 1 | 10 | 112 | 29 | 83 | 74% | 11-4 | 3.08 | 1.13 |
| 2004-07-04 | Derek Lowe | R | 31 | L 4-10 | @ ATL | 16 | 103 | L | 4.1 | 8 | 8 | 8 | 1 | 2 | 1 | 81 | 32 | 49 | 60% | 6-8 | 6.00 | 1.70 |
| 2004-07-06 | Tim Wakefield | R | 38 | L 11-0 | vs OAK | 15 | 268 | W | 7.0 | 3 | 0 | 0 | 0 | 1 | 6 | 96 | 31 | 65 | 68% | 5-5 | 3.96 | 1.31 |
| 2004-07-07 | Pedro Martinez | R | 33 | L 11-3 | vs OAK | 18 | 306 | W | 7.0 | 5 | 3 | 2 | 0 | 1 | 7 | 102 | 32 | 70 | 69% | 9-3 | 3.66 | 1.13 |
| 2004-07-08 | Curt Schilling | R | 38 | L 8-7 | vs OAK | 18 | 356 | - | 5.1 | 11 | 3 | 3 | 1 | 0 | 8 | 119 | 36 | 83 | 70% | 11-4 | 3.17 | 1.17 |
| 2004-07-09 | Bronson Arroyo | R | 27 | L 7-0 | vs TEX | 14 | 43 | W | 8.0 | 3 | 0 | 0 | 0 | 1 | 7 | 108 | 38 | 70 | 65% | 3-7 | 4.09 | 1.27 |
| 2004-07-10 | Derek Lowe | R | 31 | L 14-6 | vs TEX | 17 | 104 | W | 7.0 | 4 | 6 | 0 | 1 | 3 | 5 | 112 | 39 | 73 | 65% | 7-8 | 5.55 | 1.65 |
| 2004-07-11 | Tim Wakefield | R | 38 | W 5-6 | vs TEX | 16 | 269 | - | 6.0 | 12 | 5 | 5 | 3 | 1 | 5 | 109 | 33 | 76 | 70% | 5-5 | 4.16 | 1.36 |
| 2004-07-15 | Derek Lowe | R | 31 | L 1-8 | @ ANA | 18 | 105 | L | 4.2 | 9 | 4 | 4 | 0 | 3 | 4 | 118 | 47 | 71 | 60% | 7-9 | 5.69 | 1.70 |
| 2004-07-16 | Pedro Martinez | R | 33 | W 4-2 | @ ANA | 19 | 307 | W | 6.0 | 5 | 2 | 2 | 1 | 4 | 8 | 119 | 54 | 65 | 55% | 10-3 | 3.63 | 1.15 |
| 2004-07-17 | Tim Wakefield | R | 38 | L 3-8 | @ ANA | 17 | 270 | L | 4.0 | 8 | 5 | 5 | 2 | 1 | 4 | 79 | 24 | 55 | 70% | 5-6 | 4.42 | 1.39 |
| 2004-07-18 | Curt Schilling | R | 38 | W 6-2 | @ ANA | 19 | 357 | W | 8.0 | 3 | 1 | 1 | 1 | 0 | 7 | 118 | 38 | 80 | 68% | 12-4 | 3.05 | 1.12 |
| 2004-07-19 | Bronson Arroyo | R | 27 | L 4-8 | @ SEA | 15 | 44 | - | 7.0 | 3 | 1 | 1 | 0 | 2 | 12 | 106 | 37 | 69 | 65% | 3-7 | 3.88 | 1.23 |
| 2004-07-20 | Derek Lowe | R | 31 | W 9-7 | @ SEA | 19 | 106 | W | 5.0 | 9 | 4 | 4 | 0 | 2 | 2 | 109 | 48 | 61 | 56% | 8-9 | 5.77 | 1.73 |
| 2004-07-21 | Pedro Martinez | R | 33 | W 5-10 | vs BAL | 20 | 308 | L | 6.2 | 9 | 8 | 8 | 1 | 1 | 7 | 110 | 40 | 70 | 64% | 10-4 | 4.02 | 1.17 |
| 2004-07-22 | Abe Alvarez | L | 22 | W 3-8 | vs BAL | 1 | 1 | L | 5.0 | 8 | 5 | 5 | 2 | 5 | 2 | 95 | 46 | 49 | 52% | 0-1 | 9.00 | 2.60 |
| 2004-07-22 | Tim Wakefield | R | 38 | L 4-0 | vs BAL | 18 | 271 | W | 7.0 | 8 | 0 | 0 | 0 | 0 | 4 | 108 | 29 | 79 | 73% | 6-6 | 4.15 | 1.38 |
| 2004-07-23 | Curt Schilling | R | 38 | W 7-8 | vs NYA | 20 | 358 | - | 5.1 | 10 | 7 | 7 | 1 | 2 | 3 | 112 | 38 | 74 | 66% | 12-4 | 3.37 | 1.16 |
| 2004-07-24 | Bronson Arroyo | R | 27 | L 11-10 | vs NYA | 16 | 45 | - | 5.2 | 10 | 8 | 6 | 0 | 0 | 4 | 103 | 36 | 67 | 65% | 3-7 | 4.19 | 1.26 |
| 2004-07-25 | Derek Lowe | R | 31 | L 9-6 | vs NYA | 20 | 107 | W | 6.2 | 7 | 4 | 2 | 0 | 3 | 5 | 118 | 47 | 71 | 60% | 9-9 | 5.56 | 1.71 |
| 2004-07-26 | Pedro Martinez | R | 33 | W 12-5 | @ BAL | 21 | 309 | W | 6.1 | 7 | 5 | 5 | 1 | 2 | 5 | 105 | 34 | 71 | 68% | 11-4 | 4.14 | 1.18 |
| 2004-07-28 | Curt Schilling | R | 38 | L 1-4 | @ BAL | 21 | 359 | L | 7.0 | 7 | 4 | 4 | 2 | 0 | 2 | 85 | 21 | 64 | 75% | 12-5 | 3.45 | 1.15 |
| 2004-07-30 | Bronson Arroyo | R | 27 | W 8-2 | @ MIN | 17 | 46 | W | 7.1 | 8 | 2 | 2 | 0 | 0 | 8 | 99 | 29 | 70 | 71% | 4-7 | 4.08 | 1.25 |
| 2004-07-31 | Derek Lowe | R | 31 | L 4-5 | @ MIN | 21 | 108 | - | 7.1 | 8 | 4 | 4 | 1 | 3 | 4 | 99 | 32 | 67 | 68% | 9-9 | 5.54 | 1.70 |
| 2004-08-01 | Pedro Martinez | R | 33 | L 3-4 | @ MIN | 22 | 310 | - | 7.0 | 7 | 2 | 2 | 0 | 1 | 11 | 108 | 39 | 69 | 64% | 11-4 | 4.06 | 1.17 |
| 2004-08-02 | Tim Wakefield | R | 38 | W 6-3 | @ TBA | 19 | 272 | W | 7.0 | 4 | 3 | 3 | 1 | 4 | 3 | 111 | 48 | 63 | 57% | 7-6 | 4.14 | 1.36 |
| 2004-08-03 | Curt Schilling | R | 38 | W 5-2 | @ TBA | 22 | 360 | W | 9.0 | 6 | 2 | 2 | 1 | 1 | 7 | 117 | 32 | 85 | 73% | 13-5 | 3.37 | 1.13 |
| 2004-08-04 | Bronson Arroyo | R | 27 | L 4-5 | @ TBA | 18 | 47 | L | 7.0 | 6 | 5 | 4 | 1 | 2 | 5 | 120 | 43 | 77 | 64% | 4-8 | 4.15 | 1.24 |
| 2004-08-06 | Derek Lowe | R | 31 | L 3-4 | @ DET | 22 | 109 | L | 7.0 | 9 | 4 | 4 | 0 | 2 | 3 | 107 | 48 | 59 | 55% | 9-10 | 5.52 | 1.69 |
| 2004-08-07 | Pedro Martinez | R | 33 | W 7-4 | @ DET | 23 | 311 | W | 7.0 | 5 | 2 | 1 | 0 | 2 | 11 | 117 | 39 | 78 | 67% | 12-4 | 3.93 | 1.17 |
| 2004-08-08 | Tim Wakefield | R | 38 | W 11-9 | @ DET | 20 | 273 | W | 5.0 | 8 | 7 | 7 | 6 | 0 | 2 | 78 | 23 | 55 | 71% | 8-6 | 4.47 | 1.37 |
| 2004-08-09 | Curt Schilling | R | 38 | W 3-8 | vs TBA | 23 | 361 | L | 5.0 | 10 | 6 | 6 | 3 | 2 | 3 | 99 | 30 | 69 | 70% | 13-6 | 3.60 | 1.17 |
| 2004-08-10 | Bronson Arroyo | R | 27 | L 8-4 | vs TBA | 19 | 48 | W | 6.2 | 7 | 3 | 3 | 0 | 2 | 6 | 99 | 38 | 61 | 62% | 5-8 | 4.13 | 1.25 |
| 2004-08-11 | Derek Lowe | R | 31 | L 14-4 | vs TBA | 23 | 110 | W | 5.2 | 8 | 3 | 1 | 0 | 1 | 4 | 89 | 29 | 60 | 67% | 10-10 | 5.33 | 1.68 |
| 2004-08-12 | Pedro Martinez | R | 33 | L 6-0 | vs TBA | 24 | 312 | W | 9.0 | 6 | 0 | 0 | 0 | 0 | 10 | 109 | 37 | 72 | 66% | 13-4 | 3.71 | 1.14 |
| 2004-08-13 | Tim Wakefield | R | 38 | W 7-8 | vs CHA | 21 | 274 | L | 6.1 | 6 | 6 | 6 | 2 | 1 | 3 | 100 | 31 | 69 | 69% | 8-7 | 4.67 | 1.36 |
| 2004-08-14 | Curt Schilling | R | 38 | L 4-3 | vs CHA | 24 | 362 | W | 8.0 | 5 | 3 | 3 | 2 | 2 | 3 | 106 | 36 | 70 | 66% | 14-6 | 3.59 | 1.15 |
| 2004-08-15 | Bronson Arroyo | R | 27 | W 4-5 | vs CHA | 20 | 49 | L | 7.0 | 6 | 3 | 3 | 0 | 0 | 3 | 100 | 38 | 62 | 62% | 5-9 | 4.12 | 1.22 |
| 2004-08-16 | Derek Lowe | R | 31 | L 8-4 | vs TOR | 24 | 111 | W | 7.0 | 5 | 4 | 3 | 0 | 1 | 7 | 103 | 35 | 68 | 66% | 11-10 | 5.26 | 1.64 |
| 2004-08-17 | Pedro Martinez | R | 33 | L 5-4 | vs TOR | 25 | 313 | - | 7.0 | 8 | 4 | 4 | 2 | 0 | 6 | 105 | 31 | 74 | 70% | 13-4 | 3.77 | 1.14 |
| 2004-08-18 | Tim Wakefield | R | 38 | L 6-4 | vs TOR | 22 | 275 | W | 8.0 | 5 | 2 | 2 | 0 | 1 | 5 | 103 | 34 | 69 | 67% | 9-7 | 4.53 | 1.33 |
| 2004-08-20 | Curt Schilling | R | 38 | W 10-1 | @ CHA | 25 | 363 | W | 7.0 | 3 | 0 | 0 | 0 | 0 | 6 | 80 | 20 | 60 | 75% | 15-6 | 3.45 | 1.13 |
| 2004-08-21 | Bronson Arroyo | R | 27 | W 10-7 | @ CHA | 21 | 50 | W | 5.2 | 7 | 5 | 5 | 1 | 3 | 4 | 102 | 36 | 66 | 65% | 6-9 | 4.30 | 1.25 |
| 2004-08-22 | Derek Lowe | R | 31 | W 6-5 | @ CHA | 25 | 112 | - | 6.2 | 7 | 5 | 5 | 2 | 2 | 3 | 108 | 35 | 73 | 68% | 11-10 | 5.31 | 1.63 |
| 2004-08-23 | Pedro Martinez | R | 33 | L 0-3 | @ TOR | 26 | 314 | L | 7.0 | 4 | 3 | 3 | 1 | 3 | 10 | 115 | 40 | 75 | 65% | 13-5 | 3.78 | 1.13 |
| 2004-08-24 | Tim Wakefield | R | 38 | W 5-4 | @ TOR | 23 | 276 | W | 5.0 | 10 | 3 | 3 | 1 | 2 | 4 | 109 | 42 | 67 | 61% | 10-7 | 4.56 | 1.36 |
| 2004-08-25 | Curt Schilling | R | 38 | W 11-5 | @ TOR | 26 | 364 | W | 6.1 | 7 | 1 | 1 | 0 | 0 | 9 | 101 | 29 | 72 | 71% | 16-6 | 3.38 | 1.13 |
| 2004-08-26 | Bronson Arroyo | R | 28 | L 4-1 | vs DET | 22 | 51 | W | 7.1 | 6 | 1 | 0 | 0 | 2 | 8 | 103 | 34 | 69 | 67% | 7-9 | 4.06 | 1.24 |
| 2004-08-27 | Derek Lowe | R | 31 | L 5-3 | vs DET | 26 | 113 | W | 8.0 | 7 | 3 | 3 | 1 | 0 | 7 | 103 | 30 | 73 | 71% | 12-10 | 5.21 | 1.59 |
| 2004-08-28 | Pedro Martinez | R | 33 | L 5-1 | vs DET | 27 | 315 | W | 7.0 | 4 | 1 | 1 | 0 | 2 | 8 | 99 | 36 | 63 | 64% | 14-5 | 3.68 | 1.12 |
| 2004-08-29 | Tim Wakefield | R | 38 | L 6-1 | vs DET | 24 | 277 | W | 8.0 | 3 | 1 | 1 | 1 | 1 | 7 | 98 | 27 | 71 | 72% | 11-7 | 4.38 | 1.32 |
| 2004-08-31 | Curt Schilling | R | 38 | L 10-7 | vs ANA | 27 | 365 | W | 7.2 | 9 | 3 | 3 | 0 | 0 | 4 | 102 | 28 | 74 | 73% | 17-6 | 3.38 | 1.13 |
| 2004-09-01 | Bronson Arroyo | R | 28 | L 12-7 | vs ANA | 23 | 52 | - | 2.2 | 6 | 5 | 4 | 0 | 4 | 2 | 67 | 30 | 37 | 55% | 7-9 | 4.25 | 1.29 |
| 2004-09-02 | Derek Lowe | R | 31 | L 4-3 | vs ANA | 27 | 114 | W | 7.1 | 7 | 3 | 3 | 0 | 1 | 6 | 114 | 40 | 74 | 65% | 13-10 | 5.15 | 1.57 |
| 2004-09-03 | Pedro Martinez | R | 33 | L 2-0 | vs TEX | 28 | 316 | W | 7.0 | 4 | 0 | 0 | 0 | 1 | 9 | 109 | 32 | 77 | 71% | 15-5 | 3.54 | 1.11 |
| 2004-09-04 | Tim Wakefield | R | 38 | W 6-8 | vs TEX | 25 | 278 | L | 6.0 | 8 | 8 | 8 | 2 | 2 | 4 | 96 | 29 | 67 | 70% | 11-8 | 4.67 | 1.33 |
| 2004-09-05 | Curt Schilling | R | 38 | L 6-5 | vs TEX | 28 | 366 | W | 8.1 | 5 | 3 | 3 | 2 | 0 | 10 | 103 | 31 | 72 | 70% | 18-6 | 3.38 | 1.11 |
| 2004-09-06 | Bronson Arroyo | R | 28 | W 8-3 | @ OAK | 24 | 53 | W | 6.2 | 7 | 3 | 3 | 2 | 0 | 2 | 87 | 26 | 61 | 70% | 8-9 | 4.23 | 1.28 |
| 2004-09-07 | Derek Lowe | R | 31 | W 7-1 | @ OAK | 28 | 115 | W | 6.1 | 5 | 1 | 1 | 0 | 4 | 1 | 107 | 49 | 58 | 54% | 14-10 | 5.02 | 1.56 |
| 2004-09-08 | Pedro Martinez | R | 33 | W 8-3 | @ OAK | 29 | 317 | W | 6.0 | 2 | 0 | 0 | 0 | 3 | 6 | 83 | 30 | 53 | 64% | 16-5 | 3.43 | 1.10 |
| 2004-09-09 | Tim Wakefield | R | 38 | L 1-7 | @ SEA | 26 | 279 | L | 4.2 | 7 | 7 | 2 | 1 | 3 | 2 | 107 | 44 | 63 | 59% | 11-9 | 4.63 | 1.35 |
| 2004-09-10 | Curt Schilling | R | 38 | W 13-2 | @ SEA | 29 | 367 | W | 7.0 | 4 | 2 | 2 | 1 | 0 | 5 | 90 | 26 | 64 | 71% | 19-6 | 3.35 | 1.09 |
| 2004-09-11 | Bronson Arroyo | R | 28 | W 9-0 | @ SEA | 25 | 54 | W | 7.0 | 4 | 0 | 0 | 0 | 0 | 6 | 84 | 26 | 58 | 69% | 9-9 | 4.04 | 1.25 |
| 2004-09-12 | Derek Lowe | R | 31 | L 0-2 | @ SEA | 29 | 116 | L | 7.0 | 5 | 2 | 2 | 1 | 1 | 6 | 107 | 42 | 65 | 61% | 14-11 | 4.92 | 1.53 |
| 2004-09-14 | Pedro Martinez | R | 33 | W 2-5 | vs TBA | 30 | 318 | L | 6.0 | 3 | 2 | 2 | 2 | 5 | 10 | 113 | 44 | 69 | 61% | 16-6 | 3.42 | 1.11 |
| 2004-09-15 | Tim Wakefield | R | 38 | L 8-6 | vs TBA | 27 | 280 | - | 5.0 | 6 | 4 | 4 | 0 | 3 | 2 | 96 | 36 | 60 | 63% | 11-9 | 4.71 | 1.37 |
| 2004-09-16 | Curt Schilling | R | 38 | L 11-4 | vs TBA | 30 | 368 | W | 7.2 | 8 | 4 | 4 | 1 | 2 | 6 | 104 | 29 | 75 | 72% | 20-6 | 3.40 | 1.09 |
| 2004-09-17 | Bronson Arroyo | R | 28 | W 3-2 | @ NYA | 26 | 55 | - | 6.0 | 4 | 2 | 2 | 1 | 1 | 3 | 89 | 34 | 55 | 62% | 9-9 | 4.01 | 1.23 |
| 2004-09-18 | Derek Lowe | R | 31 | L 4-14 | @ NYA | 30 | 117 | L | 1.0 | 4 | 7 | 6 | 0 | 3 | 1 | 48 | 23 | 25 | 52% | 14-12 | 5.20 | 1.57 |
| 2004-09-19 | Pedro Martinez | R | 33 | L 1-11 | @ NYA | 31 | 319 | L | 5.0 | 8 | 8 | 8 | 3 | 3 | 4 | 96 | 35 | 61 | 64% | 16-7 | 3.69 | 1.13 |
| 2004-09-20 | Tim Wakefield | R | 38 | W 6-9 | vs BAL | 28 | 281 | L | 4.1 | 5 | 8 | 7 | 1 | 5 | 7 | 102 | 46 | 56 | 55% | 11-10 | 4.96 | 1.39 |
| 2004-09-21 | Curt Schilling | R | 38 | L 3-2 | vs BAL | 31 | 369 | - | 8.0 | 3 | 0 | 0 | 0 | 1 | 14 | 111 | 24 | 87 | 78% | 20-6 | 3.27 | 1.07 |
| 2004-09-22 | Bronson Arroyo | R | 28 | L 7-6 | vs BAL | 27 | 56 | - | 5.1 | 6 | 5 | 5 | 1 | 2 | 7 | 99 | 34 | 65 | 66% | 9-9 | 4.15 | 1.24 |
| 2004-09-23 | Derek Lowe | R | 31 | W 7-9 | vs BAL | 31 | 118 | - | 5.0 | 9 | 5 | 4 | 1 | 1 | 4 | 99 | 31 | 68 | 69% | 14-12 | 5.26 | 1.58 |
| 2004-09-24 | Pedro Martinez | R | 33 | W 4-6 | vs NYA | 32 | 320 | L | 7.1 | 9 | 5 | 5 | 1 | 2 | 5 | 117 | 43 | 74 | 63% | 16-8 | 3.78 | 1.15 |
| 2004-09-25 | Tim Wakefield | R | 38 | L 12-5 | vs NYA | 29 | 282 | - | 6.1 | 5 | 5 | 3 | 1 | 2 | 1 | 88 | 32 | 56 | 64% | 11-10 | 4.95 | 1.38 |
| 2004-09-26 | Curt Schilling | R | 38 | L 11-4 | vs NYA | 32 | 370 | W | 7.0 | 1 | 2 | 2 | 0 | 4 | 6 | 101 | 44 | 57 | 56% | 21-6 | 3.25 | 1.06 |
| 2004-09-27 | Bronson Arroyo | R | 28 | W 7-3 | @ TBA | 28 | 57 | W | 6.1 | 6 | 2 | 2 | 0 | 1 | 4 | 93 | 29 | 64 | 69% | 10-9 | 4.09 | 1.23 |
| 2004-09-28 | Derek Lowe | R | 31 | W 10-8 | @ TBA | 32 | 119 | - | 2.1 | 8 | 5 | 5 | 0 | 2 | 0 | 44 | 21 | 23 | 52% | 14-12 | 5.42 | 1.61 |
| 2004-09-29 | Pedro Martinez | R | 33 | L 4-9 | @ TBA | 33 | 321 | L | 5.0 | 10 | 5 | 5 | 0 | 1 | 5 | 115 | 40 | 75 | 65% | 16-9 | 3.90 | 1.17 |
| 2004-10-01 | Tim Wakefield | R | 38 | W 8-3 | @ BAL | 30 | 283 | W | 6.0 | 6 | 2 | 2 | 0 | 2 | 5 | 100 | 41 | 59 | 59% | 12-10 | 4.88 | 1.38 |
| 2004-10-02 | Bronson Arroyo | R | 28 | W 7-5 | @ BAL | 29 | 58 | - | 3.0 | 1 | 0 | 0 | 0 | 0 | 1 | 48 | 19 | 29 | 60% | 10-9 | 4.02 | 1.22 |
| 2004-10-02 | Pedro Astacio | R | 35 | W 7-5 | @ BAL | 1 | 304 | - | 4.0 | 7 | 4 | 4 | 1 | 0 | 4 | 70 | 22 | 48 | 69% | 0-0 | 9.00 | 1.89 |
| 2004-10-03 | Derek Lowe | R | 31 | L 2-3 | @ BAL | 33 | 120 | - | 2.0 | 3 | 1 | 1 | 0 | 1 | 2 | 53 | 23 | 30 | 57% | 14-12 | 5.41 | 1.61 |